Homo sapiens

15 known processes

PAM

peptidylglycine alpha-amidating monooxygenase

(Aliases: PAL,PHM)

PAM biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
circulatory system developmentGO:00723592620.351
cardiovascular system developmentGO:00723582620.287
vasculature developmentGO:00019441810.276
system processGO:00030083490.216
negative regulation of multicellular organismal processGO:00512413170.185
cell developmentGO:00484683280.180
regulation of cell migrationGO:00303342890.156
anatomical structure formation involved in morphogenesisGO:00486462840.150
mesonephric duct developmentGO:007217730.148
blood vessel morphogenesisGO:00485141620.142
blood vessel developmentGO:00015681720.139
regulation of cell differentiationGO:00455953930.133
oogenesisGO:004847720.129
matingGO:000761810.128
segmentationGO:003528240.128
inorganic cation transmembrane transportGO:00986621940.122
cellular calcium ion homeostasisGO:00068741170.122
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.118
vesicle mediated transportGO:00161923710.110
cellular amino acid metabolic processGO:00065201160.104
ion transmembrane transportGO:00342203380.099
proximal tubule developmentGO:007201410.098
epithelial cell proliferationGO:00506731280.096
spinal cord developmentGO:002151040.095
enzyme linked receptor protein signaling pathwayGO:00071673030.088
regulation of system processGO:00440571010.088
calcium ion transmembrane transportGO:0070588760.085
embryonic morphogenesisGO:0048598850.082
regulation of cell motilityGO:20001452990.081
memoryGO:000761330.075
calcium ion homeostasisGO:00550741220.074
membrane organizationGO:00610242920.074
regulation of cellular amino acid metabolic processGO:000652160.073
biological adhesionGO:00226103310.073
post embryonic developmentGO:000979120.072
cell adhesionGO:00071553250.071
cellular cation homeostasisGO:00300031630.070
skeletal system developmentGO:0001501790.069
regulation of kinase activityGO:00435493140.067
secretionGO:00469032540.066
positive regulation of cellular component organizationGO:00511303760.066
positive regulation of phosphorylationGO:00423273940.066
cyclic nucleotide metabolic processGO:0009187820.065
regulation of camp metabolic processGO:0030814520.063
regulation of cellular amine metabolic processGO:0033238110.063
cation transmembrane transportGO:00986552380.063
endothelial cell proliferationGO:0001935650.062
osteoblast differentiationGO:0001649920.062
positive regulation of cell proliferationGO:00082843010.061
nephric duct developmentGO:007217640.060
negative regulation of cell proliferationGO:00082852280.059
regulation of cellular component movementGO:00512703340.058
female gamete generationGO:000729220.058
associative learningGO:000830610.058
organ morphogenesisGO:00098871470.058
metal ion homeostasisGO:00550651690.058
cellular ketone metabolic processGO:0042180800.057
regulation of cellular ketone metabolic processGO:0010565500.057
sodium ion transportGO:0006814610.057
cation transportGO:00068123310.057
camp metabolic processGO:0046058610.056
epithelium developmentGO:00604292270.056
regulation of locomotionGO:00400123290.055
negative regulation of protein metabolic processGO:00512483910.055
response to oxygen containing compoundGO:19017003690.055
regulation of cyclic nucleotide metabolic processGO:0030799630.054
muscle system processGO:0003012810.054
amine metabolic processGO:0009308440.053
cellular component morphogenesisGO:00329893140.052
transmembrane transportGO:00550853990.052
cytoplasmic transportGO:00164823790.052
cellular ion homeostasisGO:00068731680.052
intracellular protein transportGO:00068862700.050
cellular response to endogenous stimulusGO:00714953360.049
angiogenesisGO:00015251470.049
sequestering of metal ionGO:0051238240.049
nervous system developmentGO:00073992930.049
calcium ion transportGO:00068161470.048
divalent inorganic cation transportGO:00725111580.046
cell substrate adhesionGO:00315891320.046
growthGO:00400072020.046
behaviorGO:00076101120.046
blastoderm segmentationGO:000735020.045
apoptotic signaling pathwayGO:00971902680.045
negative regulation of developmental processGO:00510932470.044
neurological system processGO:00508771630.044
long term memoryGO:000761620.044
regulation of cell cycleGO:00517263930.044
regulation of protein kinase activityGO:00458592890.044
ion homeostasisGO:00508012300.043
locomotory behaviorGO:000762610.043
carbohydrate derivative biosynthetic processGO:19011372070.043
organophosphate catabolic processGO:00464344300.042
cell morphogenesisGO:00009022960.042
regulation of protein localizationGO:00328802960.042
cation homeostasisGO:00550801890.042
response to calcium ionGO:0051592460.042
ras protein signal transductionGO:0007265730.042
muscle contractionGO:0006936730.042
positive regulation of developmental processGO:00510943140.041
divalent inorganic cation homeostasisGO:00725071360.041
single organism membrane organizationGO:00448022680.041
secretion by cellGO:00329402260.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.039
regulation of transferase activityGO:00513383550.039
regulation of multi organism processGO:00439001570.039
protein localization to organelleGO:00333652800.039
positive regulation of organelle organizationGO:00106381950.039
regulation of muscle system processGO:0090257530.039
ameboidal type cell migrationGO:00016671350.038
response to abiotic stimulusGO:00096283360.037
tube developmentGO:00352951250.037
cell morphogenesis involved in differentiationGO:00009041440.037
response to biotic stimulusGO:00096072760.037
regulation of epithelial cell migrationGO:0010632930.037
response to external biotic stimulusGO:00432072610.037
positive regulation of hydrolase activityGO:00513453310.037
regulation of proteolysisGO:00301622930.037
ossificationGO:00015031210.036
regenerationGO:003109940.036
embryo developmentGO:00097901230.036
defense responseGO:00069523150.035
cellular chemical homeostasisGO:00550821800.035
epithelial cell migrationGO:00106311190.035
chemical homeostasisGO:00488783060.035
negative regulation of transportGO:00510511760.035
maintenance of locationGO:00512351120.035
somitogenesisGO:000175620.034
single organism cellular localizationGO:19025803320.034
cellular metal ion homeostasisGO:00068751460.034
regulation of ion transportGO:00432691890.034
negative regulation of cellular component movementGO:00512711060.034
determination of adult lifespanGO:000834020.034
negative regulation of programmed cell deathGO:00430693210.034
negative regulation of cellular protein metabolic processGO:00322693530.034
compound eye developmentGO:004874910.034
actin cytoskeleton organizationGO:00300362070.034
inorganic ion transmembrane transportGO:00986602310.033
muscle tissue developmentGO:0060537620.033
response to growth factorGO:00708482050.033
regulation of synaptic plasticityGO:004816730.033
positive regulation of ion transmembrane transporter activityGO:0032414290.033
regulation of cell adhesionGO:00301551660.032
negative regulation of locomotionGO:00400131180.032
regulation of nervous system developmentGO:0051960880.032
cerebral cortex cell migrationGO:002179530.032
regulation of secretionGO:00510461940.032
negative regulation of catalytic activityGO:00430863350.032
actin filament based processGO:00300292240.032
response to other organismGO:00517072610.031
regulation of establishment of protein localizationGO:00702012420.031
oocyte differentiationGO:000999420.030
regulation of cellular response to growth factor stimulusGO:0090287760.030
endocytosisGO:00068971590.030
endomembrane system organizationGO:00102561960.030
metal ion transportGO:00300012720.029
cellular homeostasisGO:00197251960.029
response to bacteriumGO:00096171440.029
regulation of growthGO:00400081650.029
cellular amine metabolic processGO:0044106410.029
tripartite regional subdivisionGO:000735120.029
monocarboxylic acid metabolic processGO:00327871850.029
heart morphogenesisGO:0003007480.028
positive regulation of cellular amine metabolic processGO:003324070.028
regulation of immune responseGO:00507762010.028
cell migration involved in gastrulationGO:004207410.028
positive regulation of transportGO:00510503360.028
mitotic cell cycle processGO:19030472860.028
circulatory system processGO:00030131130.028
negative regulation of phosphate metabolic processGO:00459362670.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
regulation of actin cytoskeleton organizationGO:00329561160.028
reactive nitrogen species metabolic processGO:200105730.028
cellular response to growth factor stimulusGO:00713631970.028
regulation of metal ion transportGO:00109591200.028
negative regulation of cell migrationGO:00303361020.028
regulation of ion transmembrane transportGO:00347651320.028
mitotic cell cycle phase transitionGO:00447721620.028
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.028
regulation of cell developmentGO:00602841610.027
immune responseGO:00069553070.027
regulation of peptidase activityGO:00525471800.027
positive regulation of transferase activityGO:00513472270.027
second messenger mediated signalingGO:0019932780.027
neurogenesisGO:00220081690.027
neuron projection regenerationGO:003110210.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
tube morphogenesisGO:0035239950.026
regulation of reactive oxygen species biosynthetic processGO:190342630.026
organophosphate biosynthetic processGO:00904071630.026
protein maturationGO:00516042330.026
positive regulation of cell adhesionGO:0045785840.026
establishment of protein localization to membraneGO:00901501210.026
bmp signaling pathwayGO:0030509490.026
positive regulation of protein phosphorylationGO:00019343130.026
cellular divalent inorganic cation homeostasisGO:00725031280.026
loop of henle developmentGO:007207020.026
purine ribonucleoside metabolic processGO:00461284370.026
glial cell migrationGO:000834740.025
regulation of osteoblast differentiationGO:0045667380.025
cardiac muscle contractionGO:0060048340.025
nucleoside catabolic processGO:00091644080.025
divalent metal ion transportGO:00708381520.025
cellular modified amino acid metabolic processGO:0006575640.025
regulation of purine nucleotide metabolic processGO:19005422640.025
oocyte maturationGO:000155610.025
positive regulation of cell cycleGO:00457871400.025
wnt signaling pathwayGO:00160551560.024
cell cycle phase transitionGO:00447701730.024
endothelial cell migrationGO:0043542860.024
sequestering of calcium ionGO:0051208170.024
cell projection organizationGO:00300302520.024
cellular response to oxygen containing compoundGO:19017012760.024
retinal ganglion cell axon guidanceGO:003129020.024
potassium ion transmembrane transportGO:0071805600.024
response to virusGO:00096151260.024
regulation of protein maturationGO:19033171500.024
ribonucleotide catabolic processGO:00092614050.024
regulation of intracellular transportGO:00323861950.024
oxidation reduction processGO:00551143960.024
protein processingGO:00164852260.024
embryonic placenta developmentGO:000189210.024
cellular macromolecule catabolic processGO:00442653800.024
reactive oxygen species biosynthetic processGO:190340940.024
neuromuscular junction developmentGO:000752830.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.023
regulation of angiogenesisGO:0045765920.023
neuron projection developmentGO:00311751060.023
mitotic cell cycleGO:00002783260.023
positive regulation of mesenchymal cell proliferationGO:000205320.023
positive regulation of immune system processGO:00026842830.023
regulation of epithelial cell proliferationGO:00506781130.023
protein localization to membraneGO:00726571600.023
salivary gland morphogenesisGO:000743540.023
signal transduction by phosphorylationGO:00230142970.023
cell growthGO:00160491600.023
positive regulation of protein kinase activityGO:00458601900.023
neuron differentiationGO:00301821380.023
negative regulation of intracellular signal transductionGO:19025321830.023
morphogenesis of an epitheliumGO:0002009600.023
cellular response to glucocorticoid stimulusGO:007138540.023
nucleoside phosphate biosynthetic processGO:19012931090.023
negative regulation of cell motilityGO:20001461040.023
regulation of endothelial cell migrationGO:0010594670.022
circadian behaviorGO:004851220.022
positive regulation of cell migrationGO:00303351720.022
positive regulation of reactive oxygen species biosynthetic processGO:190342820.022
regulation of endothelial cell proliferationGO:0001936560.022
interspecies interaction between organismsGO:00444191560.022
nucleotide catabolic processGO:00091664080.022
response to woundingGO:00096111680.022
positive regulation of catabolic processGO:00098963100.022
reactive oxygen species metabolic processGO:0072593750.022
multicellular organismal agingGO:001025930.022
regulation of ion homeostasisGO:2000021730.022
positive regulation of kinase activityGO:00336742040.022
glycosyl compound catabolic processGO:19016584130.021
cellular potassium ion transportGO:0071804600.021
oocyte developmentGO:004859910.021
innate immune responseGO:00450871780.021
positive regulation of ion transportGO:0043270870.021
regulation of protein processingGO:00706131500.021
positive regulation of camp biosynthetic processGO:0030819350.021
regulation of transmembrane transporter activityGO:0022898740.021
generation of neuronsGO:00486991520.021
response to inorganic substanceGO:00100351270.021
protein localization to plasma membraneGO:0072659930.021
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.021
positive regulation of nucleotide metabolic processGO:00459812300.021
tissue morphogenesisGO:0048729960.021
regulation of transporter activityGO:0032409820.021
potassium ion transportGO:0006813620.020
regulation of reactive oxygen species metabolic processGO:2000377410.020
regulation of cytoplasmic transportGO:19036491490.020
ribose phosphate biosynthetic processGO:0046390820.020
neural crest cell migrationGO:000175520.020
small gtpase mediated signal transductionGO:0007264780.020
regulation of homeostatic processGO:00328441210.020
regulation of apoptotic signaling pathwayGO:20012331750.020
response to hormoneGO:00097251750.020
inner ear morphogenesisGO:004247240.020
engulfment of apoptotic cellGO:004365220.020
regulation of circadian sleep wake cycleGO:004274920.020
rhythmic behaviorGO:000762220.020
positive regulation of apoptotic processGO:00430652460.020
negative regulation of protein maturationGO:19033181420.020
sodium ion transmembrane transportGO:0035725590.020
negative regulation of protein modification processGO:00314002000.020
intracellular mrna localizationGO:000829810.020
regulation of defense responseGO:00313471540.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
organonitrogen compound biosynthetic processGO:19015662000.020
negative regulation of angiogenesisGO:0016525390.020
primary neural tube formationGO:001402030.020
purine containing compound catabolic processGO:00725234110.020
positive regulation of programmed cell deathGO:00430682490.019
adult locomotory behaviorGO:000834410.019
camp biosynthetic processGO:0006171470.019
positive regulation of locomotionGO:00400171860.019
anterior posterior axis specificationGO:000994820.019
immune effector processGO:00022521590.019
cytosolic calcium ion homeostasisGO:0051480890.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
glycoprotein metabolic processGO:00091001100.019
positive regulation of cell deathGO:00109422630.019
cell junction organizationGO:0034330790.019
sleepGO:003043120.019
monovalent inorganic cation transportGO:00156721280.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
positive regulation of cellular catabolic processGO:00313312840.019
negative regulation of multi organism processGO:0043901920.019
spinal cord dorsal ventral patterningGO:002151320.019
nucleoside triphosphate catabolic processGO:00091433940.019
cyclic purine nucleotide metabolic processGO:0052652600.019
midgut developmentGO:000749410.019
negative regulation of cell cycleGO:00457861930.019
organelle assemblyGO:00709251760.019
positive regulation of cyclic nucleotide metabolic processGO:0030801490.019
regulation of cell cycle processGO:00105642660.019
cellular response to transforming growth factor beta stimulusGO:0071560940.019
ribonucleoside catabolic processGO:00424544060.019
muscle cell fate commitmentGO:004269340.019
regulation of protein transportGO:00512232130.019
multi organism cellular processGO:00447641560.018
regulation of membrane potentialGO:0042391950.018
negative regulation of smoothened signaling pathwayGO:004587930.018
detection of mechanical stimulusGO:005098240.018
regulation of actin filament based processGO:00329701410.018
regulation of calcium ion transmembrane transporter activityGO:1901019280.018
positive regulation of transporter activityGO:0032411320.018
cell activationGO:00017752130.018
response to axon injuryGO:004867810.018
cyclic nucleotide biosynthetic processGO:0009190610.018
regulation of protein catabolic processGO:00421761550.018
digestive system developmentGO:0055123750.018
regulation of transmembrane transportGO:00347621390.018
mapk cascadeGO:00001652880.018
striated muscle contractionGO:0006941520.018
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.018
calcium mediated signalingGO:0019722440.018
purine containing compound biosynthetic processGO:0072522880.018
anterior posterior axis specification embryoGO:000859520.018
dephosphorylationGO:00163112090.018
purine nucleotide catabolic processGO:00061954050.018
nucleoside triphosphate metabolic processGO:00091414220.017
nucleocytoplasmic transportGO:00069131760.017
heart developmentGO:0007507950.017
regulation of cardiac muscle hypertrophy in response to stressGO:190324220.017
establishment of protein localization to plasma membraneGO:0090002680.017
regulation of phagocytosis engulfmentGO:006009920.017
jak stat cascadeGO:0007259460.017
urogenital system developmentGO:0001655650.017
regulation of protein serine threonine kinase activityGO:00719001790.017
distal tubule developmentGO:007201740.017
regulation of neuronal synaptic plasticityGO:004816810.017
regulation of anatomical structure morphogenesisGO:00226032860.017
regulation of wnt signaling pathwayGO:00301111230.017
regulation of cell growthGO:00015581350.017
renal system developmentGO:0072001630.017
nuclear transportGO:00511691790.017
pronephros morphogenesisGO:007211410.017
negative regulation of cellular component organizationGO:00511292350.017
single organism reproductive processGO:0044702980.017
ectoderm developmentGO:000739830.017
protein import into nucleusGO:00066061040.016
negative regulation of phosphorus metabolic processGO:00105632670.016
regulation of nucleotide metabolic processGO:00061402690.016
central nervous system developmentGO:00074171230.016
proteasomal protein catabolic processGO:00104981760.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
carbohydrate metabolic processGO:00059752070.016
regulation of ion transmembrane transporter activityGO:0032412720.016
positive regulation of cellular component movementGO:00512721810.016
positive regulation of cell motilityGO:20001471770.016
negative regulation of bmp signaling pathwayGO:0030514170.016
negative regulation of cell differentiationGO:00455961710.016
response to waterGO:000941520.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
plasma membrane organizationGO:00070091150.016
negative regulation of blood vessel morphogenesisGO:2000181410.016
s shaped body morphogenesisGO:007205040.016
purine nucleotide biosynthetic processGO:0006164840.016
negative regulation of phosphorylationGO:00423261740.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
spermatid differentiationGO:004851540.016
response to cytokineGO:00340972320.016
regulation of ossificationGO:0030278580.016
detection of stimulusGO:0051606850.016
regulation of mapk cascadeGO:00434082620.016
regulation of calcium ion transportGO:0051924790.016
nerve developmentGO:002167540.016
nucleoside phosphate catabolic processGO:19012924120.015
regulation of oocyte developmentGO:006028110.015
regulation of cellular protein catabolic processGO:1903362960.015
single organism cell adhesionGO:00986021790.015
metanephric collecting duct developmentGO:007220520.015
reproductive processGO:00224141060.015
g protein coupled receptor signaling pathwayGO:00071862070.015
tissue migrationGO:00901301190.015
regulation of vasculature developmentGO:1901342970.015
kidney developmentGO:0001822530.015
peripheral nervous system developmentGO:000742220.015
regulation of heart contractionGO:0008016500.015
blood circulationGO:00080151130.015
pharyngeal system developmentGO:006003720.015
viral life cycleGO:00190581320.015
alpha amino acid metabolic processGO:1901605720.015
epithelial cell differentiationGO:00308551410.015
regulation of camp biosynthetic processGO:0030817450.015
positive regulation of cellular component biogenesisGO:00440891580.015
actin filament based movementGO:0030048170.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
regulation of cell morphogenesisGO:00226041530.015
nucleotide biosynthetic processGO:00091651090.015
positive regulation of cellular amino acid metabolic processGO:004576430.015
atp metabolic processGO:00460341760.015
positive regulation of reactive oxygen species metabolic processGO:2000379240.015
establishment of protein localization to organelleGO:00725941720.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
positive regulation of adenylate cyclase activityGO:0045762120.015
regulation of cell projection organizationGO:00313441070.015
cellular response to hormone stimulusGO:00328701250.015
response to oxidative stressGO:00069791210.015
metanephric tubule developmentGO:007217030.015
positive regulation of cytosolic calcium ion concentrationGO:0007204820.014
metanephric nephron tubule developmentGO:007223430.014
single organism carbohydrate metabolic processGO:00447231930.014
sensory perceptionGO:00076001030.014
regulation of cellular component biogenesisGO:00440872810.014
cellular component assembly involved in morphogenesisGO:0010927730.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
epithelium migrationGO:00901321190.014
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.014
negative regulation of cell deathGO:00605483450.014
regulation of protein secretionGO:0050708860.014
protein localization to nucleusGO:00345041360.014
positive regulation of transmembrane transportGO:0034764410.014
response to lipidGO:00339932060.014
purine ribonucleotide biosynthetic processGO:0009152790.014
defense response to other organismGO:00985421290.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
regulation of innate immune responseGO:0045088970.014
negative regulation of hydrolase activityGO:00513461820.014
dorsal ventral pattern formationGO:0009953150.014
regulation of oocyte maturationGO:190019310.014
nucleoside monophosphate catabolic processGO:00091251590.014
regulation of neurogenesisGO:0050767820.014
cardiac muscle tissue developmentGO:0048738390.014
positive regulation of cell cycle processGO:00900681060.014
regulation of cell maturationGO:190342930.014
cell chemotaxisGO:00603261120.014
positive regulation of growthGO:0045927580.014
protein catabolic processGO:00301633250.014
cell matrix adhesionGO:0007160850.014
regulation of bmp signaling pathwayGO:0030510270.014
regulation of neuron differentiationGO:0045664700.014
heart processGO:0003015620.014
protein targeting to nucleusGO:00447441040.014
cell cell junction organizationGO:0045216690.014
positive regulation of synaptic transmissionGO:005080640.014
negative regulation of proteolysisGO:00458611320.014
purine ribonucleotide catabolic processGO:00091544040.014
protein importGO:00170381300.013
actin filament organizationGO:00070151280.013
viral processGO:00160321460.013
purine nucleoside catabolic processGO:00061523980.013
cell part morphogenesisGO:00329901370.013
regulation of ras gtpase activityGO:00323181280.013
response to transforming growth factor betaGO:0071559940.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
neural tube closureGO:000184330.013
response to acid chemicalGO:0001101660.013

PAM disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.141
inherited metabolic disorderDOID:6552420.068
musculoskeletal system diseaseDOID:172230.056
nervous system diseaseDOID:8634310.038
sensory system diseaseDOID:00501552030.038
connective tissue diseaseDOID:651090.033
carbohydrate metabolic disorderDOID:2978550.029
glycogen metabolism disorderDOID:0050728100.029
glycogen storage diseaseDOID:2747100.029
organ system cancerDOID:00506861640.028
disease of cellular proliferationDOID:145661740.028
cancerDOID:1621670.028
bone development diseaseDOID:0080006550.028
bone diseaseDOID:0080001880.028
eye and adnexa diseaseDOID:14921500.024
eye diseaseDOID:56141490.024
central nervous system diseaseDOID:3311860.021
endocrine gland cancerDOID:170260.019
acquired metabolic diseaseDOID:0060158580.015
brain diseaseDOID:936730.015
retinal diseaseDOID:56791180.014
retinal degenerationDOID:8466890.014