Homo sapiens

182 known processes

TRIM28

tripartite motif containing 28

(Aliases: TIF1B,RNF96,TF1B,KAP1,FLJ29029)

TRIM28 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
covalent chromatin modificationGO:00165692540.998
chromatin organizationGO:00063253510.998
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.997
Mouse
chromatin modificationGO:00165682980.993
histone modificationGO:00165702510.970
protein acetylationGO:00064731160.866
macromolecule methylationGO:0043414970.847
Mouse
regulation of cell cycleGO:00517263930.752
cellular macromolecule catabolic processGO:00442653800.743
protein catabolic processGO:00301633250.687
Human
cellular protein catabolic processGO:00442572610.685
negative regulation of cellular protein metabolic processGO:00322693530.610
gene silencingGO:0016458490.542
positive regulation of developmental processGO:00510943140.538
regulation of multicellular organism growthGO:004001480.530
chromatin assembly or disassemblyGO:0006333780.529
growthGO:00400072020.515
Mouse
protein acylationGO:00435431380.511
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.511
nucleosome organizationGO:0034728660.503
post embryonic developmentGO:000979120.501
mitotic cell cycleGO:00002783260.472
protein dna complex subunit organizationGO:0071824800.445
negative regulation of cell cycleGO:00457861930.401
dna repairGO:00062811980.357
methylationGO:00322591060.350
Mouse
nervous system developmentGO:00073992930.327
Fly
cell developmentGO:00484683280.312
Mouse Fly
determination of adult lifespanGO:000834020.293
negative regulation of mitotic cell cycleGO:00459301020.292
negative regulation of protein metabolic processGO:00512483910.288
cell cycle checkpointGO:00000751170.275
strand invasionGO:004214820.274
methylation dependent chromatin silencingGO:000634630.273
cellular response to dna damage stimulusGO:00069743790.235
proteolysis involved in cellular protein catabolic processGO:00516032440.230
regulation of growthGO:00400081650.218
organelle fissionGO:00482851490.213
response to oxygen containing compoundGO:19017003690.208
rna processingGO:00063962550.208
developmental process involved in reproductionGO:0003006660.207
Mouse
cellular protein complex assemblyGO:00436231880.200
mitotic cell cycle processGO:19030472860.188
regulation of cellular ketone metabolic processGO:0010565500.187
protein alkylationGO:0008213740.184
dna methylation or demethylationGO:0044728190.181
Mouse
oogenesisGO:004847720.178
single organism reproductive processGO:0044702980.176
Mouse
negative regulation of protein modification processGO:00314002000.174
embryo development ending in birth or egg hatchingGO:0009792340.170
Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.163
negative regulation of chromosome organizationGO:2001251480.163
proteasomal protein catabolic processGO:00104981760.160
regulation of cell cycle phase transitionGO:19019871260.159
multicellular organismal agingGO:001025930.155
protein ubiquitinationGO:00165673140.154
negative regulation of cell cycle processGO:00109481210.148
positive regulation of multicellular organism growthGO:004001860.148
peptidyl lysine modificationGO:00182051440.144
negative regulation of intracellular signal transductionGO:19025321830.137
positive regulation of growthGO:0045927580.135
microtubule based processGO:00070172100.135
positive regulation of cellular amine metabolic processGO:003324070.134
dephosphorylationGO:00163112090.128
locomotory behaviorGO:000762610.122
neuron projection developmentGO:00311751060.121
Fly
purine nucleoside triphosphate catabolic processGO:00091463920.120
cellular response to oxygen containing compoundGO:19017012760.117
regulation of cell developmentGO:00602841610.112
chromatin assemblyGO:0031497610.107
response to other organismGO:00517072610.106
chromatin silencingGO:0006342120.105
reproductive processGO:00224141060.102
Mouse
negative regulation of cell cycle phase transitionGO:1901988890.102
regulation of protein acetylationGO:1901983250.101
regulation of chromosome organizationGO:00330441030.101
cellular response to growth factor stimulusGO:00713631970.100
Human
cell agingGO:0007569520.097
internal peptidyl lysine acetylationGO:0018393970.097
spindle organizationGO:0007051530.097
reproductive system developmentGO:0061458560.096
Mouse
negative regulation of mitotic cell cycle phase transitionGO:1901991850.096
ras protein signal transductionGO:0007265730.091
protein modification by small protein conjugationGO:00324463420.089
regulation of dna metabolic processGO:00510521530.087
histone acetylationGO:0016573930.086
nuclear divisionGO:00002801280.085
chromatin remodelingGO:0006338550.085
chromosome segregationGO:00070591140.084
regulation of stress activated protein kinase signaling cascadeGO:0070302850.084
regulation of mitotic cell cycleGO:00073461890.084
response to abiotic stimulusGO:00096283360.083
peptidyl lysine acetylationGO:00183941010.083
regulation of protein modification by small protein conjugation or removalGO:19033201070.077
vesicle mediated transportGO:00161923710.076
regulation of proteolysisGO:00301622930.076
regulation of gene expression epigeneticGO:0040029730.075
Mouse
lens development in camera type eyeGO:000208820.074
generation of neuronsGO:00486991520.073
Fly
regulation of chromatin organizationGO:1902275560.073
cell cycle phase transitionGO:00447701730.073
dna conformation changeGO:00711031130.072
cytoplasmic transportGO:00164823790.072
regulation of cell cycle processGO:00105642660.071
protein methylationGO:0006479740.068
regulation of cellular response to stressGO:00801352440.067
neurogenesisGO:00220081690.067
Fly
female gamete generationGO:000729220.067
dna packagingGO:0006323770.066
multicellular organism growthGO:003526480.066
positive regulation of ubiquitin protein transferase activityGO:0051443180.066
positive regulation of organelle organizationGO:00106381950.063
positive regulation of transferase activityGO:00513472270.061
cellular component morphogenesisGO:00329893140.061
Mouse Fly
peptidyl threonine dephosphorylationGO:003597070.060
behaviorGO:00076101120.060
dna integrity checkpointGO:0031570710.059
microtubule cytoskeleton organizationGO:00002261760.057
protein dephosphorylationGO:0006470810.055
regulation of locomotionGO:00400123290.054
positive regulation of developmental growthGO:0048639160.054
cellular macromolecular complex assemblyGO:00346223240.053
response to biotic stimulusGO:00096072760.053
mitotic nuclear divisionGO:00070671190.053
anatomical structure formation involved in morphogenesisGO:00486462840.052
positive regulation of programmed cell deathGO:00430682490.052
modification dependent protein catabolic processGO:00199412090.051
striated muscle myosin thick filament assemblyGO:007168820.050
dna replicationGO:00062601160.050
mitotic cell cycle phase transitionGO:00447721620.048
mitotic sister chromatid segregationGO:0000070530.048
cell divisionGO:00513011680.047
multicellular organismal reproductive processGO:0048609400.047
positive regulation of hydrolase activityGO:00513453310.047
regulation of histone modificationGO:0031056470.046
embryo developmentGO:00097901230.046
Mouse
amine metabolic processGO:0009308440.045
histone methylationGO:0016571600.045
nucleotide catabolic processGO:00091664080.045
oocyte differentiationGO:000999420.045
rna interferenceGO:001624640.044
mitotic cell cycle checkpointGO:0007093680.043
stress activated protein kinase signaling cascadeGO:0031098940.043
negative regulation of phosphate metabolic processGO:00459362670.042
regulation of chromatin modificationGO:1903308510.042
circulatory system developmentGO:00723592620.042
notch signaling pathwayGO:0007219310.042
regulation of ras protein signal transductionGO:00465781550.042
cellular amino acid metabolic processGO:00065201160.041
positive regulation of chromatin modificationGO:1903310300.041
regulation of developmental growthGO:0048638300.040
maintenance of locationGO:00512351120.039
cellular response to organonitrogen compoundGO:00714171240.039
mrna metabolic processGO:00160711750.039
dna hypermethylationGO:004402610.038
positive regulation of cellular catabolic processGO:00313312840.037
negative regulation of phosphorus metabolic processGO:00105632670.037
positive regulation of protein ubiquitinationGO:0031398530.037
negative regulation of gene expression epigeneticGO:0045814190.037
dna templated transcription elongationGO:0006354250.036
glycosyl compound catabolic processGO:19016584130.036
response to external biotic stimulusGO:00432072610.035
negative regulation of multicellular organismal processGO:00512413170.035
positive regulation of chromosome organizationGO:2001252410.034
negative regulation of proteolysisGO:00458611320.033
translationGO:00064121320.033
cardiovascular system developmentGO:00723582620.033
agingGO:0007568660.032
positive regulation of peptidase activityGO:0010952880.032
negative regulation of cellular component organizationGO:00511292350.032
regulation of small gtpase mediated signal transductionGO:00510561560.032
reproductionGO:0000003630.032
regulation of endopeptidase activityGO:00525481700.031
negative regulation of programmed cell deathGO:00430693210.031
regulation of response to external stimulusGO:00321012220.031
regulation of immune responseGO:00507762010.031
negative regulation of protein acetylationGO:1901984110.031
cellular senescenceGO:0090398340.031
positive regulation of histone modificationGO:0031058290.031
nucleoside catabolic processGO:00091644080.031
dna damage checkpointGO:0000077680.030
nucleotide excision repairGO:0006289310.030
regulation of cellular protein catabolic processGO:1903362960.029
regulation of cysteine type endopeptidase activityGO:20001161270.029
purine ribonucleoside metabolic processGO:00461284370.029
osteoblast differentiationGO:0001649920.029
gonad developmentGO:0008406340.028
ncrna processingGO:0034470830.028
sex differentiationGO:0007548450.028
negative regulation of chromatin modificationGO:1903309210.028
internal protein amino acid acetylationGO:00064751010.028
cell cycle arrestGO:0007050710.027
nucleoside phosphate catabolic processGO:19012924120.027
response to organonitrogen compoundGO:00102431560.027
regulation of mitotic cell cycle phase transitionGO:19019901180.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
regulation of bindingGO:00510981110.027
organ morphogenesisGO:00098871470.026
cellular amine metabolic processGO:0044106410.026
regulation of protein ubiquitinationGO:0031396950.026
negative regulation of apoptotic processGO:00430663160.026
regulation of response to dna damage stimulusGO:2001020940.026
regulation of notch signaling pathwayGO:0008593180.026
macromolecule deacylationGO:0098732410.026
dna methylation on cytosineGO:003277630.026
ubiquitin dependent protein catabolic processGO:00065112060.025
system processGO:00030083490.025
response to decreased oxygen levelsGO:0036293960.025
protein import into nucleusGO:00066061040.024
ribonucleoside catabolic processGO:00424544060.024
ncrna metabolic processGO:00346601080.024
signal transduction by p53 class mediatorGO:0072331720.023
response to inorganic substanceGO:00100351270.023
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.023
response to radiationGO:00093141510.023
myosin filament assemblyGO:003103420.023
nuclear transportGO:00511691790.022
cell type specific apoptotic processGO:00972851250.022
regulation of proteasomal protein catabolic processGO:0061136870.022
negative regulation of catabolic processGO:00098951040.022
mitotic dna integrity checkpointGO:0044774300.022
positive regulation of ligase activityGO:0051351190.022
purine nucleoside monophosphate catabolic processGO:00091281580.022
posttranscriptional regulation of gene expressionGO:00106082130.022
Human
protein processingGO:00164852260.022
regulation of immune effector processGO:0002697910.021
protein dna complex assemblyGO:0065004640.021
positive regulation of dna metabolic processGO:0051054730.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
cellular ketone metabolic processGO:0042180800.020
definitive hemopoiesisGO:006021620.019
defense responseGO:00069523150.019
digestive tract developmentGO:0048565750.019
developmental growthGO:0048589480.019
Mouse
nucleoside triphosphate catabolic processGO:00091433940.018
mapk cascadeGO:00001652880.018
nucleocytoplasmic transportGO:00069131760.018
positive regulation of cell deathGO:00109422630.018
brain developmentGO:0007420970.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
microtubule organizing center organizationGO:0031023620.017
regulation of multi organism processGO:00439001570.017
posttranscriptional gene silencingGO:0016441250.017
positive regulation of apoptotic processGO:00430652460.017
regulation of cell activationGO:00508651250.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
negative regulation of cell deathGO:00605483450.017
dna modificationGO:0006304270.017
Mouse
regulation of meiosisGO:004002030.017
cellular response to nitrogen compoundGO:19016991440.016
viral life cycleGO:00190581320.016
regulation of ligase activityGO:0051340290.016
negative regulation of developmental processGO:00510932470.016
sensory organ developmentGO:0007423520.016
protein localization to organelleGO:00333652800.016
regulation of jnk cascadeGO:0046328730.016
immune effector processGO:00022521590.016
development of primary sexual characteristicsGO:0045137350.016
actin filament based processGO:00300292240.016
protein localization to nucleusGO:00345041360.016
positive regulation of proteolysisGO:00458621420.016
cell projection organizationGO:00300302520.015
Fly
regulation of mrna metabolic processGO:1903311530.015
organelle assemblyGO:00709251760.015
regulation of cell growthGO:00015581350.015
spermatogenesisGO:0007283220.015
negative regulation of organelle organizationGO:00106391260.015
mrna processingGO:00063971330.015
purine ribonucleoside triphosphate catabolic processGO:00092073910.015
sexual reproductionGO:0019953370.015
regulation of cell divisionGO:00513021160.015
somatic diversification of immunoglobulins involved in immune responseGO:000220830.015
tube morphogenesisGO:0035239950.015
negative regulation of cellular catabolic processGO:0031330830.014
small gtpase mediated signal transductionGO:0007264780.014
purine containing compound catabolic processGO:00725234110.014
tissue morphogenesisGO:0048729960.014
Mouse
ribosome assemblyGO:004225590.014
intracellular protein transportGO:00068862700.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.014
response to ionizing radiationGO:0010212650.014
regulation of neuron deathGO:1901214560.014
mrna splicing via spliceosomeGO:0000398890.014
cellular response to cytokine stimulusGO:00713451810.014
regulation of immunoglobulin productionGO:000263740.014
protein maturationGO:00516042330.014
alcohol catabolic processGO:0046164200.014
positive regulation of spindle checkpointGO:009023270.014
negative regulation of stress activated mapk cascadeGO:0032873190.013
rna splicingGO:00083801310.013
protein polyubiquitinationGO:00002091100.013
base excision repairGO:0006284210.013
cellular response to organic cyclic compoundGO:00714071270.013
Human
myosin filament organizationGO:003103320.013
defense response to other organismGO:00985421290.013
negative regulation of rna splicingGO:0033119150.013
negative regulation of dna metabolic processGO:0051053570.013
Mouse
negative regulation of notch signaling pathwayGO:0045746100.013
multi organism reproductive processGO:0044703540.013
Mouse
single organism carbohydrate metabolic processGO:00447231930.013
response to nutrient levelsGO:0031667810.013
protein deacylationGO:0035601390.012
segmentationGO:003528240.012
regulation of cellular amino acid metabolic processGO:000652160.012
embryonic morphogenesisGO:0048598850.012
Mouse
regulation of cell differentiationGO:00455953930.012
oocyte developmentGO:004859910.012
regulation of protein processingGO:00706131500.012
regulation of gene silencingGO:0060968240.012
metencephalon developmentGO:002203720.012
regulation of spindle checkpointGO:0090231120.012
mitotic dna damage checkpointGO:0044773280.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.011
immune responseGO:00069553070.011
pharyngeal system developmentGO:006003720.011
meiotic nuclear divisionGO:0007126100.011
purine nucleoside catabolic processGO:00061523980.011
histone deacetylationGO:0016575320.011
lymphocyte activationGO:00466491330.011
multicellular organism reproductionGO:0032504420.011
blastocyst developmentGO:000182430.011
central nervous system developmentGO:00074171230.011
response to temperature stimulusGO:0009266220.011
cell part morphogenesisGO:00329901370.010
Fly
regulation of cell migrationGO:00303342890.010
blastoderm segmentationGO:000735020.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.010
protein sumoylationGO:0016925250.010
response to nitrogen compoundGO:19016981840.010
negative regulation of catalytic activityGO:00430863350.010
neuron deathGO:0070997650.010
gamete generationGO:0007276250.010
regulation of secretion by cellGO:19035301770.010
cell activationGO:00017752130.010
head developmentGO:00603221080.010
cellular homeostasisGO:00197251960.010

TRIM28 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.118
Human
disease of cellular proliferationDOID:145661740.118
Human
nervous system diseaseDOID:8634310.111
central nervous system diseaseDOID:3311860.111
organ system cancerDOID:00506861640.083
Human
neurodegenerative diseaseDOID:12891020.047