Homo sapiens

51 known processes

PNKP

polynucleotide kinase 3'-phosphatase

(Aliases: PNK,MCSZ,EIEE10)

PNKP biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna ligation involved in dna repairGO:005110340.971
dna repairGO:00062811980.874
cellular response to dna damage stimulusGO:00069743790.627
double strand break repairGO:00063021010.405
dna recombinationGO:0006310770.311
pro b cell differentiationGO:000232810.257
nucleotide excision repairGO:0006289310.227
base excision repairGO:0006284210.202
dna ligationGO:0006266100.144
non recombinational repairGO:0000726140.142
response to abiotic stimulusGO:00096283360.141
regulation of dna metabolic processGO:00510521530.129
limbic system developmentGO:002176130.103
central nervous system developmentGO:00074171230.080
glycosyl compound catabolic processGO:19016584130.073
negative regulation of dna metabolic processGO:0051053570.063
mitochondrion organizationGO:00070051560.062
response to inorganic substanceGO:00100351270.060
hemopoiesisGO:00300971800.057
single strand break repairGO:000001260.056
negative regulation of cell deathGO:00605483450.054
cellular macromolecule catabolic processGO:00442653800.052
v d j recombinationGO:003315130.052
negative regulation of programmed cell deathGO:00430693210.050
response to hypoxiaGO:0001666960.049
establishment of protein localization to organelleGO:00725941720.047
ribonucleotide catabolic processGO:00092614050.047
dna catabolic processGO:0006308490.047
enzyme linked receptor protein signaling pathwayGO:00071673030.046
negative regulation of apoptotic processGO:00430663160.045
response to drugGO:0042493810.041
hippocampus developmentGO:002176610.040
regulation of cellular amino acid metabolic processGO:000652160.039
response to oxygen containing compoundGO:19017003690.039
t cell differentiation in thymusGO:003307740.038
double strand break repair via nonhomologous end joiningGO:0006303100.038
cytoplasmic transportGO:00164823790.035
negative regulation of dna recombinationGO:004591060.035
cell projection organizationGO:00300302520.035
immune effector processGO:00022521590.035
immune responseGO:00069553070.034
brain developmentGO:0007420970.034
nucleic acid phosphodiester bond hydrolysisGO:00903051020.034
peptidyl tyrosine modificationGO:00182121700.033
regulation of fibroblast proliferationGO:0048145320.030
purine nucleoside triphosphate catabolic processGO:00091463920.028
ras protein signal transductionGO:0007265730.027
nucleotide excision repair dna incisionGO:003368370.027
response to radiationGO:00093141510.027
neurogenesisGO:00220081690.026
organophosphate catabolic processGO:00464344300.025
cellular macromolecular complex assemblyGO:00346223240.025
regulation of cellular ketone metabolic processGO:0010565500.025
regulation of cellular amine metabolic processGO:0033238110.024
response to decreased oxygen levelsGO:0036293960.023
positive regulation of developmental processGO:00510943140.023
negative regulation of cellular protein metabolic processGO:00322693530.023
positive regulation of cellular amino acid metabolic processGO:004576430.022
protein importGO:00170381300.022
endosomal transportGO:00161971290.022
regulation of cell differentiationGO:00455953930.021
positive regulation of cell proliferationGO:00082843010.021
regulation of locomotionGO:00400123290.021
base excision repair dna ligationGO:000628820.021
gtp catabolic processGO:00061842370.020
purine nucleotide catabolic processGO:00061954050.020
nervous system developmentGO:00073992930.020
regulation of response to external stimulusGO:00321012220.019
protein targeting to nucleusGO:00447441040.019
positive regulation of cellular amine metabolic processGO:003324070.019
positive regulation of cytoskeleton organizationGO:0051495830.019
regulation of peptidase activityGO:00525471800.018
head developmentGO:00603221080.018
protein targetingGO:00066051870.018
hematopoietic or lymphoid organ developmentGO:00485341860.018
fibroblast proliferationGO:0048144330.017
neuron differentiationGO:00301821380.017
positive regulation of cell developmentGO:0010720920.017
cellular ketone metabolic processGO:0042180800.016
regulation of secretion by cellGO:19035301770.016
somatic muscle developmentGO:000752510.016
response to cytokineGO:00340972320.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
immune system developmentGO:00025201950.015
cellular amino acid metabolic processGO:00065201160.015
regulation of protein localizationGO:00328802960.015
positive regulation of protein phosphorylationGO:00019343130.015
compound eye developmentGO:004874910.015
positive regulation of cell differentiationGO:00455972110.015
protein autophosphorylationGO:00467771230.015
regulation of protein complex assemblyGO:00432541470.015
purine containing compound catabolic processGO:00725234110.015
positive regulation of nervous system developmentGO:0051962540.015
chemical homeostasisGO:00488783060.015
intracellular protein transportGO:00068862700.015
generation of neuronsGO:00486991520.015
regulation of neurogenesisGO:0050767820.015
defense response to other organismGO:00985421290.014
protein localization to nucleusGO:00345041360.014
nucleoside catabolic processGO:00091644080.014
protein catabolic processGO:00301633250.014
amine metabolic processGO:0009308440.014
positive regulation of neurogenesisGO:0050769490.014
purine ribonucleotide catabolic processGO:00091544040.014
cellular response to cytokine stimulusGO:00713451810.014
negative regulation of transportGO:00510511760.014
regulation of cell developmentGO:00602841610.014
protein localization to organelleGO:00333652800.014
single organism cellular localizationGO:19025803320.014
ribonucleoside triphosphate catabolic processGO:00092033910.014
secretion by cellGO:00329402260.014
purine nucleoside triphosphate metabolic processGO:00091444120.013
regulation of dna recombinationGO:0000018230.013
chromosome segregationGO:00070591140.013
peptidyl tyrosine phosphorylationGO:00181081700.013
protein import into nucleusGO:00066061040.013
forebrain developmentGO:0030900260.013
lymphocyte differentiationGO:0030098350.013
response to reactive oxygen speciesGO:0000302610.013
small gtpase mediated signal transductionGO:0007264780.013
cell activationGO:00017752130.013
guanosine containing compound catabolic processGO:19010692390.013
response to growth factorGO:00708482050.012
cellular homeostasisGO:00197251960.012
regulation of proteolysisGO:00301622930.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
positive regulation of locomotionGO:00400171860.012
carbohydrate metabolic processGO:00059752070.012
regulation of nervous system developmentGO:0051960880.012
cell morphogenesisGO:00009022960.012
negative regulation of catalytic activityGO:00430863350.012
regulation of homeostatic processGO:00328441210.012
positive regulation of cellular component organizationGO:00511303760.011
ribonucleoside catabolic processGO:00424544060.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
regulation of growthGO:00400081650.011
nucleotide catabolic processGO:00091664080.011
protein modification by small protein conjugationGO:00324463420.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
microtubule cytoskeleton organizationGO:00002261760.011
protein ubiquitinationGO:00165673140.011
nucleocytoplasmic transportGO:00069131760.011
single organism nuclear importGO:19025931040.011
response to oxidative stressGO:00069791210.011
post embryonic developmentGO:000979120.011
nuclear importGO:00511701060.011
defense response to virusGO:0051607710.011
gtp metabolic processGO:00460392390.011
rho protein signal transductionGO:0007266260.011
regulation of cell growthGO:00015581350.011
lymphoid progenitor cell differentiationGO:000232030.011
nuclear transportGO:00511691790.011
mapk cascadeGO:00001652880.011
locomotory behaviorGO:000762610.011
regulation of secretionGO:00510461940.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
rna processingGO:00063962550.011
defense responseGO:00069523150.011
dna catabolic process exonucleolyticGO:0000738170.011
microtubule based processGO:00070172100.010
adaptive immune responseGO:0002250490.010
protein processingGO:00164852260.010
guanosine containing compound metabolic processGO:19010682440.010
leukocyte activationGO:00453211640.010
cell growthGO:00160491600.010
meiotic chromosome segregationGO:004513240.010
nucleoside phosphate catabolic processGO:19012924120.010
lymphocyte activationGO:00466491330.010

PNKP disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.149
disease of cellular proliferationDOID:145661740.149
cancerDOID:1621670.149
immune system diseaseDOID:29141550.042
primary ciliary dyskinesiaDOID:9562270.035
nervous system diseaseDOID:8634310.005
central nervous system diseaseDOID:3311860.005
brain diseaseDOID:936730.002
idiopathic generalized epilepsyDOID:1827210.001
epilepsy syndromeDOID:1826410.001
electroclinical syndromeDOID:0050701320.001
neonatal period electroclinical syndromeDOID:0050702190.001
ohtahara syndromeDOID:0050709170.001
infantile epileptic encephalopathyDOID:2481120.001