IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

DYNC2LI1

dynein, cytoplasmic 2, light intermediate chain 1

(Aliases: DKFZp564A033,LIC3,D2LIC)

Ensembl: ENSG00000138036
Entrez: 51626
HPRD: 13116
HGNC: 24595
UniProtKB: Q8TCX1

Process Predictions
Disease Predictions

DYNC2LI1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
cilium assembly	GO:0042384	63	0.378
cilium morphogenesis	GO:0060271	75	0.144
cell projection assembly	GO:0030031	126	0.071
cilium organization	GO:0044782	68	0.064
cellular component assembly involved in morphogenesis	GO:0010927	73	0.059
single organism membrane organization	GO:0044802	268	0.058
intracellular protein transport	GO:0006886	270	0.055
purine nucleotide catabolic process	GO:0006195	405	0.055
microtubule based process	GO:0007017	210	0.055
lipid metabolic process	GO:0006629	381	0.049
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.043
endomembrane system organization	GO:0010256	196	0.042
cytoplasmic transport	GO:0016482	379	0.042
protein localization to organelle	GO:0033365	280	0.042
purine ribonucleoside metabolic process	GO:0046128	437	0.040
positive regulation of transport	GO:0051050	336	0.040
microtubule based movement	GO:0007018	32	0.040
cellular component morphogenesis	GO:0032989	314	0.039
single organism cellular localization	GO:1902580	332	0.038
cell projection organization	GO:0030030	252	0.038
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.036
protein localization to membrane	GO:0072657	160	0.033
organelle assembly	GO:0070925	176	0.032
purine ribonucleoside catabolic process	GO:0046130	398	0.031
nucleoside triphosphate catabolic process	GO:0009143	394	0.031
cytoskeleton dependent intracellular transport	GO:0030705	21	0.030
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.028
regulation of protein localization	GO:0032880	296	0.028
nucleoside triphosphate metabolic process	GO:0009141	422	0.028
membrane organization	GO:0061024	292	0.027
regulation of establishment of protein localization	GO:0070201	242	0.027
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.027
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.027
nucleoside catabolic process	GO:0009164	408	0.027
cell part morphogenesis	GO:0032990	137	0.026
nucleoside phosphate catabolic process	GO:1901292	412	0.026
ribonucleoside catabolic process	GO:0042454	406	0.026
cell morphogenesis	GO:0000902	296	0.025
vesicle mediated transport	GO:0016192	371	0.025
sensory perception of smell	GO:0007608	2	0.024
regulation of cell motility	GO:2000145	299	0.024
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.024
nucleotide catabolic process	GO:0009166	408	0.023
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.023
protein targeting	GO:0006605	187	0.023
post embryonic development	GO:0009791	2	0.023
positive regulation of cellular component organization	GO:0051130	376	0.023
establishment of protein localization to organelle	GO:0072594	172	0.022
purine ribonucleotide catabolic process	GO:0009154	404	0.022
cellular amino acid metabolic process	GO:0006520	116	0.022
regulation of purine nucleotide catabolic process	GO:0033121	205	0.022
photoreceptor cell differentiation	GO:0046530	2	0.022
regulation of intracellular transport	GO:0032386	195	0.022
organophosphate catabolic process	GO:0046434	430	0.022
positive regulation of catabolic process	GO:0009896	310	0.022
regulation of anatomical structure morphogenesis	GO:0022603	286	0.022
regulation of protein transport	GO:0051223	213	0.021
establishment of protein localization to membrane	GO:0090150	121	0.021
single organism membrane fusion	GO:0044801	37	0.021
maintenance of location	GO:0051235	112	0.021
cellular ketone metabolic process	GO:0042180	80	0.020
epithelium development	GO:0060429	227	0.020
oxidation reduction process	GO:0055114	396	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.020
glycosyl compound catabolic process	GO:1901658	413	0.020
cellular response to dna damage stimulus	GO:0006974	379	0.020
transmembrane transport	GO:0055085	399	0.020
protein targeting to peroxisome	GO:0006625	15	0.020
cofactor metabolic process	GO:0051186	87	0.020
protein localization to plasma membrane	GO:0072659	93	0.019
guanosine containing compound catabolic process	GO:1901069	239	0.019
ras protein signal transduction	GO:0007265	73	0.019
regulation of cellular component movement	GO:0051270	334	0.018
intraciliary transport	GO:0042073	7	0.018
ribonucleotide catabolic process	GO:0009261	405	0.018
regulation of purine nucleotide metabolic process	GO:1900542	264	0.018
positive regulation of nucleotide metabolic process	GO:0045981	230	0.018
positive regulation of developmental process	GO:0051094	314	0.018
spermatid differentiation	GO:0048515	4	0.018
segmentation	GO:0035282	4	0.018
cellular lipid metabolic process	GO:0044255	303	0.018
oogenesis	GO:0048477	2	0.018
positive regulation of cellular catabolic process	GO:0031331	284	0.017
gtp metabolic process	GO:0046039	239	0.017
nervous system development	GO:0007399	293	0.017
negative regulation of blood pressure	GO:0045776	3	0.017
golgi organization	GO:0007030	38	0.017
regulation of cell migration	GO:0030334	289	0.017
purine nucleoside catabolic process	GO:0006152	398	0.017
cell projection morphogenesis	GO:0048858	129	0.017
positive regulation of hydrolase activity	GO:0051345	331	0.017
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.017
regulation of nucleoside metabolic process	GO:0009118	209	0.017
locomotory behavior	GO:0007626	1	0.017
amine metabolic process	GO:0009308	44	0.017
adult locomotory behavior	GO:0008344	1	0.017
regulation of nucleotide catabolic process	GO:0030811	205	0.017
determination of adult lifespan	GO:0008340	2	0.016
positive regulation of organelle organization	GO:0010638	195	0.016
regulation of cellular response to stress	GO:0080135	244	0.016
regulation of proteolysis	GO:0030162	293	0.016
cellular homeostasis	GO:0019725	196	0.016
regulation of transferase activity	GO:0051338	355	0.016
rho protein signal transduction	GO:0007266	26	0.016
cellular amine metabolic process	GO:0044106	41	0.016
negative regulation of cellular protein metabolic process	GO:0032269	353	0.016
purine containing compound catabolic process	GO:0072523	411	0.015
regulation of cell cycle	GO:0051726	393	0.015
response to oxygen containing compound	GO:1901700	369	0.015
regulation of nucleotide metabolic process	GO:0006140	269	0.015
anatomical structure homeostasis	GO:0060249	100	0.015
innate immune response	GO:0045087	178	0.015
positive regulation of intracellular protein transport	GO:0090316	76	0.015
female gamete generation	GO:0007292	2	0.015
regulation of cell cycle process	GO:0010564	266	0.015
golgi vesicle transport	GO:0048193	80	0.015
regulation of mitochondrion organization	GO:0010821	54	0.015
gtp catabolic process	GO:0006184	237	0.014
protein modification by small protein conjugation	GO:0032446	342	0.014
cation homeostasis	GO:0055080	189	0.014
eye photoreceptor cell differentiation	GO:0001754	2	0.014
axon cargo transport	GO:0008088	2	0.014
alpha amino acid metabolic process	GO:1901605	72	0.014
chemical homeostasis	GO:0048878	306	0.014
lipid biosynthetic process	GO:0008610	177	0.014
microtubule based transport	GO:0010970	21	0.014
protein import	GO:0017038	130	0.014
guanosine containing compound metabolic process	GO:1901068	244	0.014
small gtpase mediated signal transduction	GO:0007264	78	0.014
regulation of cellular amino acid metabolic process	GO:0006521	6	0.013
system process	GO:0003008	349	0.013
positive regulation of nucleotide catabolic process	GO:0030813	185	0.013
regulation of cellular amine metabolic process	GO:0033238	11	0.013
cellular protein complex assembly	GO:0043623	188	0.013
mitotic cell cycle	GO:0000278	326	0.013
protein homooligomerization	GO:0051260	100	0.013
sequestering of metal ion	GO:0051238	24	0.013
regulation of ras protein signal transduction	GO:0046578	155	0.013
regulation of locomotion	GO:0040012	329	0.013
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.013
multicellular organismal aging	GO:0010259	3	0.013
positive regulation of intracellular transport	GO:0032388	104	0.013
organonitrogen compound biosynthetic process	GO:1901566	200	0.013
apoptotic signaling pathway	GO:0097190	268	0.013
response to abiotic stimulus	GO:0009628	336	0.013
negative regulation of catalytic activity	GO:0043086	335	0.012
nitrogen compound transport	GO:0071705	191	0.012
mitochondrion organization	GO:0007005	156	0.012
positive regulation of protein transport	GO:0051222	135	0.012
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	89	0.012
neuromuscular junction development	GO:0007528	3	0.012
sequestering of calcium ion	GO:0051208	17	0.012
metal ion homeostasis	GO:0055065	169	0.012
cellular macromolecular complex assembly	GO:0034622	324	0.012
negative regulation of developmental process	GO:0051093	247	0.012
regulation of cell morphogenesis	GO:0022604	153	0.012
positive regulation of purine nucleotide catabolic process	GO:0033123	185	0.012
negative regulation of cell death	GO:0060548	345	0.011
ribonucleoside monophosphate catabolic process	GO:0009158	158	0.011
spermatid development	GO:0007286	4	0.011
convergent extension	GO:0060026	1	0.011
cell adhesion	GO:0007155	325	0.011
ion homeostasis	GO:0050801	230	0.011
negative regulation of organelle organization	GO:0010639	126	0.011
neurological system process	GO:0050877	163	0.011
positive regulation of cell proliferation	GO:0008284	301	0.011
cellular macromolecule catabolic process	GO:0044265	380	0.011
regulation of vesicle mediated transport	GO:0060627	130	0.011
regulation of gtpase activity	GO:0043087	180	0.011
peroxisomal transport	GO:0043574	15	0.011
maintenance of location in cell	GO:0051651	62	0.011
negative regulation of cell cycle	GO:0045786	193	0.011
negative regulation of phosphate metabolic process	GO:0045936	267	0.011
immune response	GO:0006955	307	0.011
growth	GO:0040007	202	0.011
positive regulation of nucleoside metabolic process	GO:0045979	186	0.011
circulatory system development	GO:0072359	262	0.011
oocyte development	GO:0048599	1	0.011
reactive oxygen species biosynthetic process	GO:1903409	4	0.011
receptor metabolic process	GO:0043112	81	0.011
regulation of protein kinase activity	GO:0045859	289	0.011
embryonic epithelial tube formation	GO:0001838	4	0.011
negative regulation of multicellular organismal process	GO:0051241	317	0.011
negative regulation of cellular amino acid metabolic process	GO:0045763	2	0.011
regulation of apoptotic signaling pathway	GO:2001233	175	0.011
vesicle organization	GO:0016050	62	0.011
mitotic cell cycle process	GO:1903047	286	0.011
defense response	GO:0006952	315	0.011
negative regulation of cell proliferation	GO:0008285	228	0.011
protein oligomerization	GO:0051259	173	0.011
negative regulation of phosphorus metabolic process	GO:0010563	267	0.011
response to cytokine	GO:0034097	232	0.011
atp metabolic process	GO:0046034	176	0.010
establishment of protein localization to plasma membrane	GO:0090002	68	0.010
negative regulation of protein metabolic process	GO:0051248	391	0.010
generation of neurons	GO:0048699	152	0.010
regulation of proteasomal protein catabolic process	GO:0061136	87	0.010
positive regulation of cellular amine metabolic process	GO:0033240	7	0.010
dna repair	GO:0006281	198	0.010
establishment of protein localization to peroxisome	GO:0072663	15	0.010
cellular ion homeostasis	GO:0006873	168	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.010
regulation of intracellular protein transport	GO:0033157	123	0.010
cardiovascular system development	GO:0072358	262	0.010
posttranscriptional regulation of gene expression	GO:0010608	213	0.010
negative regulation of cellular component organization	GO:0051129	235	0.010

DYNC2LI1 disease predictions

Disease	DO term ID	Size	Probability
sensory system disease	DOID:0050155	203	0.098
nervous system disease	DOID:863	431	0.098
meckel syndrome	DOID:0050778	11	0.087
central nervous system disease	DOID:331	186	0.047
eye and adnexa disease	DOID:1492	150	0.047
eye disease	DOID:5614	149	0.047
musculoskeletal system disease	DOID:17	223	0.039
retinal disease	DOID:5679	118	0.033
joubert syndrome	DOID:0050777	18	0.031
disease of metabolism	DOID:0014667	295	0.025
inherited metabolic disorder	DOID:655	242	0.024
muscular disease	DOID:0080000	114	0.021
muscle tissue disease	DOID:66	113	0.018
myopathy	DOID:423	104	0.015
disease of cellular proliferation	DOID:14566	174	0.012
cardiovascular system disease	DOID:1287	106	0.012
neurodegenerative disease	DOID:1289	102	0.012
brain disease	DOID:936	73	0.011

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network