Homo sapiens

186 known processes

GBA

glucosidase, beta, acid

(Aliases: GBA1,GCB,GLUC)

GBA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
natural killer cell activation involved in immune responseGO:000232320.878
golgi to vacuole transportGO:000689630.799
positive regulation of natural killer cell activationGO:003281680.659
natural killer cell mediated immunityGO:0002228230.481
positive regulation of natural killer cell mediated cytotoxicityGO:0045954110.472
regulation of natural killer cell activationGO:003281490.465
positive regulation of exocytosisGO:0045921350.433
post golgi vesicle mediated transportGO:0006892360.425
lysosomal transportGO:0007041330.413
regulation of natural killer cell mediated cytotoxicityGO:0042269160.408
cytoplasmic transportGO:00164823790.386
positive regulation of secretion by cellGO:19035321080.386
regulation of microtubule based processGO:0032886740.384
cytoskeleton dependent intracellular transportGO:0030705210.354
regulation of immune responseGO:00507762010.330
positive regulation of leukocyte activationGO:0002696800.305
innate immune responseGO:00450871780.305
golgi vesicle transportGO:0048193800.304
positive regulation of immune system processGO:00026842830.303
positive regulation of secretionGO:00510471160.287
vacuolar transportGO:0007034340.269
regulation of exocytosisGO:0017157460.263
cell activationGO:00017752130.239
regulation of lymphocyte mediated immunityGO:0002706330.238
positive regulation of leukocyte degranulationGO:004330230.238
defense responseGO:00069523150.231
regulation of leukocyte mediated immunityGO:0002703380.229
positive regulation of innate immune responseGO:0045089790.223
regulation of immune effector processGO:0002697910.217
natural killer cell mediated cytotoxicityGO:0042267230.216
regulation of defense responseGO:00313471540.213
exocytosisGO:0006887710.211
protein stabilizationGO:0050821640.211
positive regulation of defense responseGO:0031349870.209
immune effector processGO:00022521590.208
secretionGO:00469032540.207
cell killingGO:0001906340.204
lymphocyte mediated immunityGO:0002449480.203
microtubule based movementGO:0007018320.202
regulation of innate immune responseGO:0045088970.193
positive regulation of immune responseGO:00507781590.192
regulation of secretion by cellGO:19035301770.190
immune responseGO:00069553070.188
regulated secretory pathwayGO:0045055200.185
apoptotic signaling pathwayGO:00971902680.181
secretion by cellGO:00329402260.180
regulation of cellular component movementGO:00512703340.178
positive regulation of transportGO:00510503360.173
regulation of regulated secretory pathwayGO:1903305100.172
positive regulation of natural killer cell mediated immunityGO:0002717120.169
regulation of secretionGO:00510461940.169
positive regulation of leukocyte mediated immunityGO:0002705240.165
regulation of leukocyte activationGO:00026941150.160
establishment of protein localization to organelleGO:00725941720.156
regulation of cell killingGO:0031341220.155
regulation of intracellular transportGO:00323861950.151
positive regulation of regulated secretory pathwayGO:190330780.145
regulation of protein stabilityGO:0031647870.145
posttranscriptional regulation of gene expressionGO:00106082130.143
natural killer cell degranulationGO:004332020.141
leukocyte mediated immunityGO:0002443590.138
regulation of vesicle mediated transportGO:00606271300.124
regulation of cell activationGO:00508651250.122
positive regulation of lymphocyte mediated immunityGO:0002708230.121
positive regulation of cell killingGO:0031343190.111
regulation of natural killer cell mediated immunityGO:0002715160.111
protein localization to organelleGO:00333652800.109
lymphocyte activationGO:00466491330.107
microtubule based processGO:00070172100.103
regulation of lymphocyte activationGO:00512491030.103
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.102
regulation of leukocyte mediated cytotoxicityGO:0001910190.100
positive regulation of cell activationGO:0050867810.099
positive regulation of lymphocyte activationGO:0051251730.098
leukocyte activationGO:00453211640.097
granzyme mediated apoptotic signaling pathwayGO:000862640.089
cell activation involved in immune responseGO:0002263300.085
regulation of organelle transport along microtubuleGO:190251320.084
positive regulation of immune effector processGO:0002699400.079
leukocyte activation involved in immune responseGO:0002366300.077
post embryonic developmentGO:000979120.064
microtubule based transportGO:0010970210.061
cellular lipid metabolic processGO:00442553030.060
regulation of microtubule based movementGO:006063260.058
regulation of cellular amino acid metabolic processGO:000652160.057
cellular amino acid metabolic processGO:00065201160.050
female gamete generationGO:000729220.049
cellular ketone metabolic processGO:0042180800.049
vesicle mediated transportGO:00161923710.045
lipid metabolic processGO:00066293810.043
amine metabolic processGO:0009308440.043
locomotory behaviorGO:000762610.041
leukocyte degranulationGO:0043299110.041
regulation of cellular amine metabolic processGO:0033238110.035
lymphocyte activation involved in immune responseGO:0002285200.035
maintenance of locationGO:00512351120.034
regulation of cellular ketone metabolic processGO:0010565500.034
carbohydrate metabolic processGO:00059752070.033
inorganic ion transmembrane transportGO:00986602310.033
multicellular organismal agingGO:001025930.032
negative regulation of catalytic activityGO:00430863350.031
single organism membrane organizationGO:00448022680.031
membrane lipid metabolic processGO:0006643530.031
cellular amine metabolic processGO:0044106410.030
cellular macromolecule catabolic processGO:00442653800.030
ion homeostasisGO:00508012300.030
nucleoside catabolic processGO:00091644080.030
cellular amide metabolic processGO:0043603690.029
purine nucleotide catabolic processGO:00061954050.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
organophosphate catabolic processGO:00464344300.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
proteolysis involved in cellular protein catabolic processGO:00516032440.028
ribonucleotide catabolic processGO:00092614050.028
golgi to lysosome transportGO:009016030.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
purine ribonucleotide catabolic processGO:00091544040.026
peripheral nervous system developmentGO:000742220.026
ribonucleoside triphosphate metabolic processGO:00091994120.025
rho protein signal transductionGO:0007266260.025
purine ribonucleoside metabolic processGO:00461284370.025
positive regulation of cellular component organizationGO:00511303760.025
regulation of leukocyte degranulationGO:004330060.025
membrane organizationGO:00610242920.025
nucleoside triphosphate metabolic processGO:00091414220.025
positive regulation of cellular amine metabolic processGO:003324070.024
ribonucleoside catabolic processGO:00424544060.024
cellular macromolecular complex assemblyGO:00346223240.024
glycosyl compound catabolic processGO:19016584130.024
nucleotide catabolic processGO:00091664080.024
purine containing compound catabolic processGO:00725234110.023
ion transmembrane transportGO:00342203380.023
cellular protein catabolic processGO:00442572610.023
cellular ion homeostasisGO:00068731680.023
transmembrane transportGO:00550853990.022
adult locomotory behaviorGO:000834410.022
neuromuscular junction developmentGO:000752830.022
nucleoside phosphate catabolic processGO:19012924120.022
organonitrogen compound biosynthetic processGO:19015662000.022
protein maturationGO:00516042330.022
purine ribonucleoside catabolic processGO:00461303980.021
cation transportGO:00068123310.021
cellular homeostasisGO:00197251960.021
lipid localizationGO:00108761060.021
phospholipid metabolic processGO:0006644990.021
purine nucleoside monophosphate metabolic processGO:00091261860.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
circulatory system developmentGO:00723592620.021
response to abiotic stimulusGO:00096283360.021
negative regulation of protein metabolic processGO:00512483910.020
purine nucleoside catabolic processGO:00061523980.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
nucleoside monophosphate metabolic processGO:00091231910.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
regulation of transferase activityGO:00513383550.020
regulation of natural killer cell degranulationGO:004332120.020
oogenesisGO:004847720.020
single organism carbohydrate metabolic processGO:00447231930.020
regulation of cellular response to stressGO:00801352440.020
nervous system developmentGO:00073992930.019
metal ion homeostasisGO:00550651690.019
lipid catabolic processGO:0016042840.019
lipid biosynthetic processGO:00086101770.019
matingGO:000761810.019
negative regulation of cellular protein metabolic processGO:00322693530.019
nucleoside triphosphate catabolic processGO:00091433940.019
cellular chemical homeostasisGO:00550821800.019
dephosphorylationGO:00163112090.018
positive regulation of cellular catabolic processGO:00313312840.018
regulation of protein kinase activityGO:00458592890.018
negative regulation of cell deathGO:00605483450.018
negative regulation of phosphorus metabolic processGO:00105632670.018
negative regulation of phosphate metabolic processGO:00459362670.018
negative regulation of multicellular organismal processGO:00512413170.018
positive regulation of hydrolase activityGO:00513453310.018
response to external biotic stimulusGO:00432072610.018
carbohydrate derivative biosynthetic processGO:19011372070.017
cation transmembrane transportGO:00986552380.017
regulation of peptidase activityGO:00525471800.017
epithelial cell proliferationGO:00506731280.017
endomembrane system organizationGO:00102561960.017
cation homeostasisGO:00550801890.017
cellular protein complex assemblyGO:00436231880.017
negative regulation of protein modification processGO:00314002000.017
spermatid differentiationGO:004851540.017
regulation of proteolysisGO:00301622930.017
positive regulation of catabolic processGO:00098963100.016
regulation of anatomical structure morphogenesisGO:00226032860.016
modification dependent protein catabolic processGO:00199412090.016
negative regulation of cellular amine metabolic processGO:003323930.016
regulation of purine nucleotide metabolic processGO:19005422640.016
ras protein signal transductionGO:0007265730.016
organic hydroxy compound metabolic processGO:19016151470.016
atp metabolic processGO:00460341760.016
neurological system processGO:00508771630.016
cellular component morphogenesisGO:00329893140.016
blastocyst developmentGO:000182430.016
cellular cation homeostasisGO:00300031630.016
glycerolipid metabolic processGO:00464861070.016
determination of adult lifespanGO:000834020.016
regulation of cytoskeleton organizationGO:00514931770.015
oocyte developmentGO:004859910.015
regulation of nucleotide metabolic processGO:00061402690.015
anion transportGO:00068201610.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
negative regulation of intracellular signal transductionGO:19025321830.015
sulfur compound metabolic processGO:00067901010.015
vacuole organizationGO:0007033440.015
gtp metabolic processGO:00460392390.015
cellular lipid catabolic processGO:0044242650.015
protein catabolic processGO:00301633250.015
small molecule biosynthetic processGO:00442831570.015
proteasomal protein catabolic processGO:00104981760.015
negative regulation of cellular component organizationGO:00511292350.015
single organism cellular localizationGO:19025803320.015
oocyte differentiationGO:000999420.015
spermatid developmentGO:000728640.015
cellular response to dna damage stimulusGO:00069743790.015
monocarboxylic acid metabolic processGO:00327871850.015
negative regulation of hydrolase activityGO:00513461820.014
alcohol metabolic processGO:00060661140.014
regulation of cellular component biogenesisGO:00440872810.014
organophosphate biosynthetic processGO:00904071630.014
metal ion transportGO:00300012720.014
negative regulation of apoptotic processGO:00430663160.014
response to oxygen containing compoundGO:19017003690.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
protein acylationGO:00435431380.014
positive regulation of organelle organizationGO:00106381950.014
glycoprotein metabolic processGO:00091001100.014
oxidation reduction processGO:00551143960.013
nitrogen compound transportGO:00717051910.013
monovalent inorganic cation transportGO:00156721280.013
calcium ion homeostasisGO:00550741220.013
mitotic cell cycleGO:00002783260.013
regulation of mapk cascadeGO:00434082620.013
regulation of protein processingGO:00706131500.013
rna processingGO:00063962550.013
regulation of locomotionGO:00400123290.013
reactive oxygen species metabolic processGO:0072593750.013
small gtpase mediated signal transductionGO:0007264780.013
positive regulation of phosphorylationGO:00423273940.013
regulation of cell migrationGO:00303342890.013
negative regulation of programmed cell deathGO:00430693210.013
response to biotic stimulusGO:00096072760.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
protein processingGO:00164852260.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
positive regulation of cell proliferationGO:00082843010.013
sequestering of metal ionGO:0051238240.013
negative regulation of synaptic transmissionGO:005080520.013
regulation of cell differentiationGO:00455953930.013
endocytosisGO:00068971590.013
hindbrain developmentGO:003090230.013
positive regulation of proteolysisGO:00458621420.013
regulation of cell cycleGO:00517263930.013
positive regulation of nucleotide metabolic processGO:00459812300.013
regenerationGO:003109940.013
regulation of ion transportGO:00432691890.013
glycerophospholipid metabolic processGO:0006650840.012
biological adhesionGO:00226103310.012
mitotic cell cycle processGO:19030472860.012
liposaccharide metabolic processGO:1903509270.012
regulation of protein maturationGO:19033171500.012
epithelium developmentGO:00604292270.012
cell projection organizationGO:00300302520.012
inorganic cation transmembrane transportGO:00986621940.012
regulation of purine nucleotide catabolic processGO:00331212050.012
endosomal transportGO:00161971290.012
actin cytoskeleton organizationGO:00300362070.012
microtubule cytoskeleton organizationGO:00002261760.012
signal transduction by phosphorylationGO:00230142970.012
regulation of multi organism processGO:00439001570.012
cell part morphogenesisGO:00329901370.012
organic anion transportGO:00157111030.012
modification dependent macromolecule catabolic processGO:00436322120.012
guanosine containing compound metabolic processGO:19010682440.012
chromatin organizationGO:00063253510.012
chromatin modificationGO:00165682980.012
system processGO:00030083490.012
fatty acid metabolic processGO:00066311150.012
wnt signaling pathwayGO:00160551560.012
response to oxidative stressGO:00069791210.012
regulation of protein localizationGO:00328802960.012
defense response to other organismGO:00985421290.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
regulation of kinase activityGO:00435493140.012
mitochondrion organizationGO:00070051560.012
regulation of nucleotide catabolic processGO:00308112050.012
covalent chromatin modificationGO:00165692540.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of endopeptidase activityGO:00525481700.012
neuron differentiationGO:00301821380.011
intracellular protein transportGO:00068862700.011
mapk cascadeGO:00001652880.011
sensory perception of painGO:001923340.011
regulation of cell cycle processGO:00105642660.011
memoryGO:000761330.011
cellular response to oxygen containing compoundGO:19017012760.011
regulation of synaptic plasticityGO:004816730.011
regulation of cytokine productionGO:00018172320.011
positive regulation of synaptic transmissionGO:005080640.011
regulation of establishment of protein localizationGO:00702012420.011
histone modificationGO:00165702510.011
guanosine containing compound catabolic processGO:19010692390.011
embryo developmentGO:00097901230.011
morphogenesis of embryonic epitheliumGO:001633140.011
cell projection assemblyGO:00300311260.011
actin filament based processGO:00300292240.011
generation of neuronsGO:00486991520.011
cell growthGO:00160491600.011
negative regulation of phosphorylationGO:00423261740.011
regulation of protein transportGO:00512232130.011
protein targetingGO:00066051870.011
regulation of growthGO:00400081650.011
blastoderm segmentationGO:000735020.011
tissue homeostasisGO:0001894630.011
cytokine productionGO:00018162470.011
regulation of cell morphogenesisGO:00226041530.011
regulation of protein serine threonine kinase activityGO:00719001790.011
reactive oxygen species biosynthetic processGO:190340940.011
atp catabolic processGO:00062001570.011
regulation of gtp catabolic processGO:00331241800.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
protein ubiquitinationGO:00165673140.011
coenzyme metabolic processGO:0006732650.011
regulation of nucleoside metabolic processGO:00091182090.011
negative regulation of cell proliferationGO:00082852280.011
nerve developmentGO:002167540.011
glycoprotein biosynthetic processGO:0009101910.011
negative regulation of locomotionGO:00400131180.011
regulation of cell motilityGO:20001452990.011
neuron developmentGO:00486661130.011
response to metal ionGO:0010038840.011
cellular response to endogenous stimulusGO:00714953360.011
divalent inorganic cation transportGO:00725111580.010
dna repairGO:00062811980.010
regulation of response to external stimulusGO:00321012220.010
reproductive processGO:00224141060.010
regulation of protein complex assemblyGO:00432541470.010
response to virusGO:00096151260.010
response to other organismGO:00517072610.010
segmentationGO:003528240.010
negative regulation of organelle organizationGO:00106391260.010
cofactor metabolic processGO:0051186870.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
calcium ion transportGO:00068161470.010
negative regulation of developmental processGO:00510932470.010
cell adhesionGO:00071553250.010
response to cytokineGO:00340972320.010
negative regulation of transferase activityGO:00513481240.010
reactive nitrogen species metabolic processGO:200105730.010
cell projection morphogenesisGO:00488581290.010

GBA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.303
inherited metabolic disorderDOID:6552420.303
lysosomal storage diseaseDOID:3211470.112
nervous system diseaseDOID:8634310.048
central nervous system diseaseDOID:3311860.048
lipid storage diseaseDOID:9455280.023
immune system diseaseDOID:29141550.015
brain diseaseDOID:936730.014
disease of cellular proliferationDOID:145661740.014
sensory system diseaseDOID:00501552030.014
eye diseaseDOID:56141490.013
eye and adnexa diseaseDOID:14921500.013
cancerDOID:1621670.013
organ system cancerDOID:00506861640.012
musculoskeletal system diseaseDOID:172230.011
neurodegenerative diseaseDOID:12891020.010
disease of mental healthDOID:150700.006
cognitive disorderDOID:1561290.003
synucleinopathyDOID:0050890220.002
parkinson s diseaseDOID:14330180.002
dementiaDOID:1307190.001
sphingolipidosisDOID:1927140.000
lewy body dementiaDOID:1221730.000