Homo sapiens

43 known processes

AEN

apoptosis enhancing nuclease

(Aliases: pp12744,FLJ12484,FLJ12562,ISG20L1)

AEN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.080
amine metabolic processGO:0009308440.056
response to abiotic stimulusGO:00096283360.047
cellular ketone metabolic processGO:0042180800.047
cytoplasmic transportGO:00164823790.046
regulation of cellular amine metabolic processGO:0033238110.044
multicellular organismal agingGO:001025930.043
regulation of cellular amino acid metabolic processGO:000652160.042
positive regulation of transportGO:00510503360.041
mitotic cell cycleGO:00002783260.039
regulation of cell cycleGO:00517263930.039
cellular amine metabolic processGO:0044106410.039
negative regulation of cellular protein metabolic processGO:00322693530.037
negative regulation of cell deathGO:00605483450.037
determination of adult lifespanGO:000834020.036
mitochondrion organizationGO:00070051560.036
rna processingGO:00063962550.036
negative regulation of catalytic activityGO:00430863350.036
positive regulation of cell deathGO:00109422630.035
apoptotic signaling pathwayGO:00971902680.035
cellular amino acid metabolic processGO:00065201160.034
regulation of cellular ketone metabolic processGO:0010565500.034
negative regulation of protein metabolic processGO:00512483910.034
negative regulation of apoptotic processGO:00430663160.033
nucleoside triphosphate metabolic processGO:00091414220.033
positive regulation of apoptotic processGO:00430652460.033
single organism membrane organizationGO:00448022680.033
cation transportGO:00068123310.032
cellular response to dna damage stimulusGO:00069743790.031
immune responseGO:00069553070.031
female gamete generationGO:000729220.030
regulation of protein localizationGO:00328802960.030
mitotic cell cycle processGO:19030472860.029
regulation of transferase activityGO:00513383550.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.029
negative regulation of phosphate metabolic processGO:00459362670.029
protein ubiquitinationGO:00165673140.029
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.029
nucleoside catabolic processGO:00091644080.029
cellular macromolecule catabolic processGO:00442653800.029
ribonucleoside triphosphate catabolic processGO:00092033910.028
regulation of cellular response to stressGO:00801352440.028
regenerationGO:003109940.028
positive regulation of cellular amine metabolic processGO:003324070.028
regulation of kinase activityGO:00435493140.028
positive regulation of cellular amino acid metabolic processGO:004576430.028
single organism cellular localizationGO:19025803320.027
intracellular protein transportGO:00068862700.027
membrane organizationGO:00610242920.027
response to oxygen containing compoundGO:19017003690.027
glycosyl compound catabolic processGO:19016584130.026
lipid metabolic processGO:00066293810.026
protein maturationGO:00516042330.026
regulation of protein kinase activityGO:00458592890.026
response to biotic stimulusGO:00096072760.026
nitrogen compound transportGO:00717051910.026
purine ribonucleoside metabolic processGO:00461284370.025
negative regulation of intracellular signal transductionGO:19025321830.025
positive regulation of cellular component organizationGO:00511303760.025
cellular macromolecular complex assemblyGO:00346223240.025
response to external biotic stimulusGO:00432072610.025
protein localization to organelleGO:00333652800.025
negative regulation of phosphorus metabolic processGO:00105632670.025
negative regulation of programmed cell deathGO:00430693210.024
purine nucleotide catabolic processGO:00061954050.024
regulation of proteolysisGO:00301622930.024
protein catabolic processGO:00301633250.024
oogenesisGO:004847720.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
positive regulation of programmed cell deathGO:00430682490.024
negative regulation of transportGO:00510511760.024
negative regulation of cell proliferationGO:00082852280.024
positive regulation of hydrolase activityGO:00513453310.023
signal transduction by phosphorylationGO:00230142970.023
nuclear transportGO:00511691790.023
dephosphorylationGO:00163112090.023
regulation of protein serine threonine kinase activityGO:00719001790.023
response to other organismGO:00517072610.023
ribonucleoside triphosphate metabolic processGO:00091994120.022
regulation of cell cycle processGO:00105642660.022
regulation of immune responseGO:00507762010.022
carbohydrate metabolic processGO:00059752070.022
regulation of establishment of protein localizationGO:00702012420.022
defense responseGO:00069523150.022
locomotory behaviorGO:000762610.022
purine containing compound catabolic processGO:00725234110.021
negative regulation of cellular component organizationGO:00511292350.021
system processGO:00030083490.021
ribonucleotide catabolic processGO:00092614050.021
metal ion transportGO:00300012720.020
nervous system developmentGO:00073992930.020
innate immune responseGO:00450871780.020
purine nucleoside catabolic processGO:00061523980.020
morphogenesis of embryonic epitheliumGO:001633140.020
memoryGO:000761330.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
purine ribonucleoside catabolic processGO:00461303980.020
regulation of apoptotic signaling pathwayGO:20012331750.020
cardiovascular system developmentGO:00723582620.020
cell projection organizationGO:00300302520.020
carbohydrate derivative biosynthetic processGO:19011372070.020
protein processingGO:00164852260.019
negative regulation of protein modification processGO:00314002000.019
chromatin organizationGO:00063253510.019
segmentationGO:003528240.019
anion transportGO:00068201610.019
regulation of cell differentiationGO:00455953930.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
positive regulation of cell proliferationGO:00082843010.019
cellular response to external stimulusGO:00714961110.019
nucleotide catabolic processGO:00091664080.019
response to radiationGO:00093141510.019
regulation of endopeptidase activityGO:00525481700.019
negative regulation of hydrolase activityGO:00513461820.019
negative regulation of organelle organizationGO:00106391260.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
circulatory system developmentGO:00723592620.018
regulation of defense responseGO:00313471540.018
ribonucleoside catabolic processGO:00424544060.018
purine ribonucleotide catabolic processGO:00091544040.018
apoptotic mitochondrial changesGO:0008637570.018
cellular response to endogenous stimulusGO:00714953360.018
organophosphate catabolic processGO:00464344300.018
positive regulation of cellular catabolic processGO:00313312840.018
biological adhesionGO:00226103310.018
intrinsic apoptotic signaling pathwayGO:00971931270.018
regulation of protein maturationGO:19033171500.018
actin filament based processGO:00300292240.017
cell cycle phase transitionGO:00447701730.017
positive regulation of phosphorylationGO:00423273940.017
regulation of ion transportGO:00432691890.017
mapk cascadeGO:00001652880.017
purine ribonucleoside triphosphate metabolic processGO:00092054110.017
negative regulation of protein maturationGO:19033181420.017
regulation of mapk cascadeGO:00434082620.017
chromatin modificationGO:00165682980.017
actin cytoskeleton organizationGO:00300362070.017
cell developmentGO:00484683280.017
cellular lipid metabolic processGO:00442553030.017
regulation of protein transportGO:00512232130.017
epithelium developmentGO:00604292270.017
neuromuscular junction developmentGO:000752830.017
protein modification by small protein conjugationGO:00324463420.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
nucleocytoplasmic transportGO:00069131760.017
regulation of peptidase activityGO:00525471800.017
regulation of locomotionGO:00400123290.017
regulation of intracellular transportGO:00323861950.017
regulation of cellular component movementGO:00512703340.017
regulation of response to dna damage stimulusGO:2001020940.017
intracellular receptor signaling pathwayGO:00305221040.017
nucleoside phosphate catabolic processGO:19012924120.016
cell growthGO:00160491600.016
secretionGO:00469032540.016
blastocyst developmentGO:000182430.016
cellular response to oxygen containing compoundGO:19017012760.016
regulation of cell migrationGO:00303342890.016
neurogenesisGO:00220081690.016
negative regulation of phosphorylationGO:00423261740.016
regulation of anatomical structure morphogenesisGO:00226032860.016
transmembrane transportGO:00550853990.016
regulation of protein processingGO:00706131500.016
nucleoside triphosphate catabolic processGO:00091433940.016
cell adhesionGO:00071553250.016
spermatid differentiationGO:004851540.016
single organism carbohydrate metabolic processGO:00447231930.016
regulation of mitotic cell cycleGO:00073461890.016
organic anion transportGO:00157111030.016
photoreceptor cell differentiationGO:004653020.016
cytokine productionGO:00018162470.016
positive regulation of catabolic processGO:00098963100.016
cellular response to nutrient levelsGO:0031669690.016
hemopoiesisGO:00300971800.015
response to lipidGO:00339932060.015
protein oligomerizationGO:00512591730.015
rhythmic behaviorGO:000762220.015
chemical homeostasisGO:00488783060.015
guanosine containing compound metabolic processGO:19010682440.015
cellular homeostasisGO:00197251960.015
modification dependent macromolecule catabolic processGO:00436322120.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
cellular response to abiotic stimulusGO:00712141170.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
regulation of response to external stimulusGO:00321012220.015
secretion by cellGO:00329402260.015
response to cytokineGO:00340972320.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
cellular protein catabolic processGO:00442572610.015
lipid transportGO:0006869900.015
organelle assemblyGO:00709251760.015
positive regulation of organelle organizationGO:00106381950.015
establishment of protein localization to organelleGO:00725941720.015
cellular component morphogenesisGO:00329893140.015
trophectodermal cell differentiationGO:000182930.015
positive regulation of developmental processGO:00510943140.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
negative regulation of cell cycleGO:00457861930.015
proteasomal protein catabolic processGO:00104981760.015
cell activationGO:00017752130.014
regulation of cell motilityGO:20001452990.014
dna repairGO:00062811980.014
ion homeostasisGO:00508012300.014
regulation of nucleotide metabolic processGO:00061402690.014
organelle localizationGO:0051640840.014
regulation of mitochondrion organizationGO:0010821540.014
blastocyst formationGO:000182530.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
cellular response to extracellular stimulusGO:0031668720.014
protein targetingGO:00066051870.014
adult locomotory behaviorGO:000834410.014
ion transmembrane transportGO:00342203380.014
maintenance of locationGO:00512351120.014
circadian behaviorGO:004851220.014
regulation of cytoskeleton organizationGO:00514931770.014
positive regulation of immune system processGO:00026842830.014
reactive oxygen species metabolic processGO:0072593750.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
cell divisionGO:00513011680.014
regulation of cell growthGO:00015581350.014
t cell differentiation in thymusGO:003307740.014
ras protein signal transductionGO:0007265730.014
organophosphate biosynthetic processGO:00904071630.014
negative regulation of proteolysisGO:00458611320.014
cell morphogenesisGO:00009022960.014
response to organic cyclic compoundGO:00140702040.014
negative regulation of multicellular organismal processGO:00512413170.014
regulation of secretionGO:00510461940.014
engulfment of apoptotic cellGO:004365220.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
positive regulation of synaptic transmissionGO:005080640.013
response to growth factorGO:00708482050.013
compound eye developmentGO:004874910.013
regulation of multi organism processGO:00439001570.013
organonitrogen compound biosynthetic processGO:19015662000.013
positive regulation of protein transportGO:00512221350.013
associative learningGO:000830610.013
single organism reproductive processGO:0044702980.013
negative regulation of cellular amine metabolic processGO:003323930.013
epithelial cell migrationGO:00106311190.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
blastoderm segmentationGO:000735020.013
negative regulation of transferase activityGO:00513481240.013
positive regulation of cellular component movementGO:00512721810.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of cytoplasmic transportGO:19036491490.013
modification dependent protein catabolic processGO:00199412090.013
oxidation reduction processGO:00551143960.013
limbic system developmentGO:002176130.013
regulation of transmembrane transportGO:00347621390.013
positive regulation of nucleotide metabolic processGO:00459812300.013
cation homeostasisGO:00550801890.013
cellular response to starvationGO:0009267580.013
regulation of protein catabolic processGO:00421761550.013
regulation of cellular component biogenesisGO:00440872810.013
posttranscriptional regulation of gene expressionGO:00106082130.013
divalent metal ion transportGO:00708381520.013
methylationGO:00322591060.013
positive regulation of protein phosphorylationGO:00019343130.013
response to extracellular stimulusGO:0009991850.013
small gtpase mediated signal transductionGO:0007264780.013
oocyte differentiationGO:000999420.013
immune effector processGO:00022521590.013
macromolecule methylationGO:0043414970.013
endomembrane system organizationGO:00102561960.013
spermatid developmentGO:000728640.013
response to uvGO:0009411730.013
protein localization to membraneGO:00726571600.013
negative regulation of cell cycle processGO:00109481210.013
angiogenesisGO:00015251470.013
positive regulation of cell migrationGO:00303351720.013
guanosine containing compound catabolic processGO:19010692390.013
cation transmembrane transportGO:00986552380.012
tissue migrationGO:00901301190.012
organelle fissionGO:00482851490.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
regulation of purine nucleotide metabolic processGO:19005422640.012
viral processGO:00160321460.012
regulation of growthGO:00400081650.012
anterior posterior axis specificationGO:000994820.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of purine nucleotide catabolic processGO:00331212050.012
regulation of cytokine productionGO:00018172320.012
histone modificationGO:00165702510.012
protein importGO:00170381300.012
endocytosisGO:00068971590.012
regulation of nucleotide catabolic processGO:00308112050.012
growthGO:00400072020.012
multi organism cellular processGO:00447641560.012
vesicle mediated transportGO:00161923710.012
reactive nitrogen species metabolic processGO:200105730.012
interspecies interaction between organismsGO:00444191560.012
regulation of secretion by cellGO:19035301770.012
regulation of dna metabolic processGO:00510521530.012
monovalent inorganic cation transportGO:00156721280.012
positive regulation of kinase activityGO:00336742040.012
rna interferenceGO:001624640.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
blood vessel developmentGO:00015681720.012
cellular response to growth factor stimulusGO:00713631970.012
negative regulation of immune system processGO:00026831360.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
peripheral nervous system developmentGO:000742220.012
regulation of synaptic plasticityGO:004816730.012
nucleus localizationGO:005164710.012
nucleoside monophosphate metabolic processGO:00091231910.012
reactive oxygen species biosynthetic processGO:190340940.012
small molecule biosynthetic processGO:00442831570.011
positive regulation of immune responseGO:00507781590.011
gtp catabolic processGO:00061842370.011
positive regulation of nucleoside metabolic processGO:00459791860.011
positive regulation of transferase activityGO:00513472270.011
motor neuron axon guidanceGO:000804520.011
cellular protein complex assemblyGO:00436231880.011
divalent inorganic cation transportGO:00725111580.011
muscle cell cellular homeostasisGO:004671630.011
protein homooligomerizationGO:00512601000.011
positive regulation of cell differentiationGO:00455972110.011
signal transduction by p53 class mediatorGO:0072331720.011
regulation of intracellular protein transportGO:00331571230.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.011
axon regenerationGO:003110310.011
epithelium migrationGO:00901321190.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
peptidyl tyrosine phosphorylationGO:00181081700.011
wnt signaling pathwayGO:00160551560.011
endosomal transportGO:00161971290.011
response to light stimulusGO:0009416870.011
cellular chemical homeostasisGO:00550821800.011
ubiquitin dependent protein catabolic processGO:00065112060.011
lipid localizationGO:00108761060.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
neurological system processGO:00508771630.011
mitotic cell cycle phase transitionGO:00447721620.011
covalent chromatin modificationGO:00165692540.011
gtp metabolic processGO:00460392390.011
positive regulation of cellular component biogenesisGO:00440891580.011
vasculature developmentGO:00019441810.011
response to nitrogen compoundGO:19016981840.011
response to nutrient levelsGO:0031667810.011
response to woundingGO:00096111680.011
hindbrain developmentGO:003090230.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.011
midgut developmentGO:000749410.011
embryonic epithelial tube formationGO:000183840.011
generation of neuronsGO:00486991520.011
positive regulation of mapk cascadeGO:00434101900.011
negative regulation of developmental processGO:00510932470.011
viral life cycleGO:00190581320.011
oocyte developmentGO:004859910.011
positive regulation of proteolysisGO:00458621420.011
establishment of protein localization to membraneGO:00901501210.011
syncytium formation by plasma membrane fusionGO:000076820.011
i kappab kinase nf kappab signalingGO:00072491660.011
inorganic cation transmembrane transportGO:00986621940.011
blood vessel morphogenesisGO:00485141620.011
regulation of cell divisionGO:00513021160.011
response to inorganic substanceGO:00100351270.011
tissue regenerationGO:004224630.011
response to oxidative stressGO:00069791210.011
sequestering of metal ionGO:0051238240.011
regulation of innate immune responseGO:0045088970.011
negative regulation of catabolic processGO:00098951040.011
response to hormoneGO:00097251750.011
regulation of meiotic cell cycleGO:005144540.011
positive regulation of protein kinase activityGO:00458601900.011
regulation of dephosphorylationGO:0035303960.011
cell fate determinationGO:000170930.011
microtubule based processGO:00070172100.011
cellular cation homeostasisGO:00300031630.011
positive regulation of locomotionGO:00400171860.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010
protein localization to nucleusGO:00345041360.010
cell substrate adhesionGO:00315891320.010
positive regulation of ion transportGO:0043270870.010
ameboidal type cell migrationGO:00016671350.010
organ formationGO:004864530.010
negative regulation of kinase activityGO:00336731060.010
cellular response to cytokine stimulusGO:00713451810.010
regulation of anatomical structure sizeGO:00900661010.010
regulation of protein stabilityGO:0031647870.010
myoblast fusionGO:000752010.010
myosin filament assemblyGO:003103420.010
positive regulation of gtpase activityGO:00435471660.010
glycoprotein metabolic processGO:00091001100.010
cellular response to uvGO:0034644320.010
cell part morphogenesisGO:00329901370.010
inner ear morphogenesisGO:004247240.010
embryonic placenta developmentGO:000189210.010
epithelial cell differentiationGO:00308551410.010
activation of immune responseGO:00022531140.010
regulation of vasculature developmentGO:1901342970.010
cellular response to lipidGO:00713961270.010
cellular response to radiationGO:0071478650.010
positive regulation of cell motilityGO:20001471770.010
cellular metal ion homeostasisGO:00068751460.010
cell cycle checkpointGO:00000751170.010
epithelial cell proliferationGO:00506731280.010

AEN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.025
cancerDOID:1621670.025
disease of metabolismDOID:00146672950.023
organ system cancerDOID:00506861640.020
musculoskeletal system diseaseDOID:172230.020
nervous system diseaseDOID:8634310.014
central nervous system diseaseDOID:3311860.014
inherited metabolic disorderDOID:6552420.014
connective tissue diseaseDOID:651090.013
sensory system diseaseDOID:00501552030.012
neurodegenerative diseaseDOID:12891020.011
bone diseaseDOID:0080001880.010
eye diseaseDOID:56141490.010
eye and adnexa diseaseDOID:14921500.010