Homo sapiens

17 known processes

PPP6C

protein phosphatase 6, catalytic subunit

(Aliases: FLJ92648,PP6,MGC12249)

PPP6C biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of wnt signaling pathwayGO:0030178690.953
canonical wnt signaling pathwayGO:00600701160.770
post embryonic developmentGO:000979120.668
regulation of dephosphorylationGO:0035303960.586
dephosphorylationGO:00163112090.493
positive regulation of phosphorylationGO:00423273940.455
endomembrane system organizationGO:00102561960.443
determination of adult lifespanGO:000834020.434
multicellular organismal agingGO:001025930.428
activation of jnkk activityGO:000725610.393
mapk cascadeGO:00001652880.355
signal transduction by phosphorylationGO:00230142970.285
positive regulation of protein phosphorylationGO:00019343130.283
regulation of phosphoprotein phosphatase activityGO:0043666230.272
regulation of kinase activityGO:00435493140.267
negative regulation of canonical wnt signaling pathwayGO:0090090550.223
regulation of protein localizationGO:00328802960.220
protein maturationGO:00516042330.217
peptidyl serine phosphorylationGO:00181051010.205
regulation of phosphatase activityGO:0010921810.199
protein autophosphorylationGO:00467771230.192
embryonic epithelial tube formationGO:000183840.188
protein processingGO:00164852260.179
mitotic cell cycleGO:00002783260.172
Yeast Worm Fly
regulation of mapk cascadeGO:00434082620.147
negative regulation of mapk cascadeGO:0043409560.147
negative regulation of stress activated protein kinase signaling cascadeGO:0070303190.147
single organism membrane organizationGO:00448022680.143
apoptotic signaling pathwayGO:00971902680.133
regulation of microtubule based processGO:0032886740.128
regulation of cellular component biogenesisGO:00440872810.126
membrane organizationGO:00610242920.126
cellular macromolecule catabolic processGO:00442653800.124
mitotic cell cycle processGO:19030472860.123
Yeast Worm Fly
negative regulation of kinase activityGO:00336731060.123
negative regulation of protein metabolic processGO:00512483910.122
negative regulation of phosphate metabolic processGO:00459362670.122
regulation of canonical wnt signaling pathwayGO:0060828880.121
negative regulation of phosphorus metabolic processGO:00105632670.120
neural tube formationGO:000184130.112
compound eye developmentGO:004874910.110
peptidyl serine modificationGO:00182091060.109
protein localization to membraneGO:00726571600.106
tor signalingGO:0031929390.105
Yeast
wnt signaling pathwayGO:00160551560.105
protein localization to plasma membraneGO:0072659930.104
organelle localizationGO:0051640840.104
Worm
negative regulation of phosphorylationGO:00423261740.102
positive regulation of protein kinase activityGO:00458601900.098
negative regulation of glial cell proliferationGO:006025320.095
negative regulation of protein modification processGO:00314002000.094
single organism cellular localizationGO:19025803320.094
Worm
proteasomal protein catabolic processGO:00104981760.093
hippo signalingGO:0035329200.089
stress activated protein kinase signaling cascadeGO:0031098940.085
negative regulation of protein processingGO:00109551420.085
positive regulation of transferase activityGO:00513472270.082
negative regulation of stress activated mapk cascadeGO:0032873190.081
regulation of protein kinase activityGO:00458592890.081
plasma membrane organizationGO:00070091150.080
microtubule based movementGO:0007018320.078
modification dependent protein catabolic processGO:00199412090.077
regulation of stress activated protein kinase signaling cascadeGO:0070302850.073
regulation of protein maturationGO:19033171500.073
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.072
negative regulation of protein phosphorylationGO:00019331400.072
negative regulation of protein transportGO:0051224750.070
g1 s transition of mitotic cell cycleGO:0000082780.069
Yeast Fly
morphogenesis of embryonic epitheliumGO:001633140.069
regulation of cell differentiationGO:00455953930.069
reproductive system developmentGO:0061458560.067
meiotic chromosome segregationGO:004513240.066
intrinsic apoptotic signaling pathwayGO:00971931270.065
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.064
vesicle mediated transportGO:00161923710.060
negative regulation of apoptotic processGO:00430663160.059
regulation of stress activated mapk cascadeGO:0032872840.056
endocytosisGO:00068971590.056
regulation of peptidase activityGO:00525471800.055
negative regulation of intracellular signal transductionGO:19025321830.055
protein localization to endoplasmic reticulumGO:0070972190.055
stress activated mapk cascadeGO:0051403930.054
negative regulation of protein serine threonine kinase activityGO:0071901570.053
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.053
microtubule cytoskeleton organizationGO:00002261760.052
Worm
covalent chromatin modificationGO:00165692540.050
cortical actin cytoskeleton organizationGO:003086690.048
Worm
nucleus localizationGO:005164710.048
cytoplasmic transportGO:00164823790.048
negative regulation of protein maturationGO:19033181420.047
regulation of protein processingGO:00706131500.047
ubiquitin dependent protein catabolic processGO:00065112060.046
intracellular protein transportGO:00068862700.045
ras protein signal transductionGO:0007265730.044
nuclear migrationGO:000709710.043
negative regulation of peptidase activityGO:0010466910.043
cellular response to endogenous stimulusGO:00714953360.043
regulation of cellular amino acid metabolic processGO:000652160.043
modification dependent macromolecule catabolic processGO:00436322120.042
trachea developmentGO:006043810.042
negative regulation of cell proliferationGO:00082852280.042
regulation of cell morphogenesis involved in differentiationGO:0010769830.041
actin filament based processGO:00300292240.040
Yeast Worm
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.040
microtubule based processGO:00070172100.039
Worm
regulation of i kappab kinase nf kappab signalingGO:00431221620.039
protein polyubiquitinationGO:00002091100.039
protein catabolic processGO:00301633250.038
cell projection organizationGO:00300302520.038
rna interferenceGO:001624640.038
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.037
carbohydrate metabolic processGO:00059752070.037
protein localization to organelleGO:00333652800.036
regulation of wnt signaling pathwayGO:00301111230.036
cell developmentGO:00484683280.036
tube developmentGO:00352951250.035
negative regulation of endopeptidase activityGO:0010951840.035
nucleoside triphosphate catabolic processGO:00091433940.034
negative regulation of cysteine type endopeptidase activityGO:2000117480.034
internal protein amino acid acetylationGO:00064751010.034
embryo developmentGO:00097901230.033
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.033
agingGO:0007568660.033
Yeast
regulation of neurogenesisGO:0050767820.033
negative regulation of hydrolase activityGO:00513461820.033
female gamete generationGO:000729220.032
cellular response to dna damage stimulusGO:00069743790.031
Yeast
negative regulation of protein kinase activityGO:0006469980.031
positive regulation of cellular amine metabolic processGO:003324070.031
epidermal cell differentiationGO:0009913450.031
negative regulation of catalytic activityGO:00430863350.029
multi organism reproductive processGO:0044703540.029
centrosome separationGO:005129930.029
positive regulation of kinase activityGO:00336742040.029
negative regulation of programmed cell deathGO:00430693210.028
regulation of sequence specific dna binding transcription factor activityGO:00510902110.028
cellular protein catabolic processGO:00442572610.028
negative regulation of cellular protein metabolic processGO:00322693530.028
segmentationGO:003528240.028
nervous system developmentGO:00073992930.027
cell morphogenesisGO:00009022960.027
gtp catabolic processGO:00061842370.027
meiosis iGO:000712740.027
programmed necrotic cell deathGO:0097300180.026
cell part morphogenesisGO:00329901370.026
regulation of cell cycle processGO:00105642660.026
enzyme linked receptor protein signaling pathwayGO:00071673030.025
guanosine containing compound metabolic processGO:19010682440.025
reproductive processGO:00224141060.025
regulation of cysteine type endopeptidase activityGO:20001161270.025
regulation of cell cycleGO:00517263930.025
anterior posterior axis specificationGO:000994820.025
regulation of small gtpase mediated signal transductionGO:00510561560.025
regulation of reactive oxygen species metabolic processGO:2000377410.024
regulation of transferase activityGO:00513383550.024
organ morphogenesisGO:00098871470.024
pattern specification processGO:0007389430.024
regulation of cellular ketone metabolic processGO:0010565500.024
regulation of cell projection organizationGO:00313441070.023
reproductionGO:0000003630.023
cell projection morphogenesisGO:00488581290.023
axon cargo transportGO:000808820.023
cellular amine metabolic processGO:0044106410.023
regulation of nervous system developmentGO:0051960880.023
macromolecule glycosylationGO:0043413630.023
regulation of protein complex assemblyGO:00432541470.022
phagocytosisGO:0006909420.022
tissue homeostasisGO:0001894630.022
cellular amide metabolic processGO:0043603690.022
negative regulation of gliogenesisGO:001401430.022
cellular component assembly involved in morphogenesisGO:0010927730.021
negative regulation of map kinase activityGO:0043407270.021
heart developmentGO:0007507950.021
negative regulation of proteolysisGO:00458611320.021
signal transduction by p53 class mediatorGO:0072331720.021
cellular macromolecular complex assemblyGO:00346223240.020
cellular ketone metabolic processGO:0042180800.020
regulation of cellular amine metabolic processGO:0033238110.020
positive regulation of exocytosisGO:0045921350.020
generation of neuronsGO:00486991520.020
anterior posterior axis specification embryoGO:000859520.020
er associated ubiquitin dependent protein catabolic processGO:0030433310.019
endodermal cell fate specificationGO:000171440.019
cardiovascular system developmentGO:00723582620.019
blastoderm segmentationGO:000735020.019
cellular response to growth factor stimulusGO:00713631970.019
negative regulation of protein localization to nucleusGO:1900181340.019
dna damage checkpointGO:0000077680.019
protein complex disassemblyGO:0043241520.019
cellular component disassemblyGO:0022411920.019
response to external biotic stimulusGO:00432072610.018
Zebrafish
negative regulation of cell differentiationGO:00455961710.018
establishment or maintenance of cell polarityGO:0007163310.018
neuromuscular junction developmentGO:000752830.018
nucleocytoplasmic transportGO:00069131760.018
response to cytokineGO:00340972320.018
regulation of endopeptidase activityGO:00525481700.018
embryo development ending in birth or egg hatchingGO:0009792340.018
rho protein signal transductionGO:0007266260.018
carbohydrate derivative biosynthetic processGO:19011372070.018
regulation of cell growthGO:00015581350.018
positive regulation of multi organism processGO:0043902560.017
protein acylationGO:00435431380.017
regulation of cellular component movementGO:00512703340.017
response to ionizing radiationGO:0010212650.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
regulation of protein serine threonine kinase activityGO:00719001790.017
amine metabolic processGO:0009308440.017
cellular homeostasisGO:00197251960.017
regulation of protein catabolic processGO:00421761550.017
cell fate determinationGO:000170930.017
cilium organizationGO:0044782680.017
regulation of protein transportGO:00512232130.017
oocyte differentiationGO:000999420.017
protein targetingGO:00066051870.017
neurogenesisGO:00220081690.017
i kappab kinase nf kappab signalingGO:00072491660.017
humoral immune responseGO:0006959490.017
fertilizationGO:0009566120.016
negative regulation of jun kinase activityGO:004350840.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
cellular protein complex assemblyGO:00436231880.016
embryonic morphogenesisGO:0048598850.016
reproductive structure developmentGO:0048608550.016
cellular response to gonadotropin stimulusGO:007137140.016
maintenance of protein location in cellGO:0032507560.016
organonitrogen compound biosynthetic processGO:19015662000.016
defense response to other organismGO:00985421290.015
defense response to bacteriumGO:0042742630.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
cellular response to fibroblast growth factor stimulusGO:0044344390.015
regulation of protein polymerizationGO:0032271630.015
positive regulation of protein complex assemblyGO:0031334860.015
secretionGO:00469032540.015
small gtpase mediated signal transductionGO:0007264780.015
positive regulation of cell deathGO:00109422630.015
growthGO:00400072020.015
regulation of transmembrane transporter activityGO:0022898740.015
blood circulationGO:00080151130.015
cell growthGO:00160491600.014
cellular lipid metabolic processGO:00442553030.014
reactive oxygen species metabolic processGO:0072593750.014
regulation of heart contractionGO:0008016500.014
regulation of cell developmentGO:00602841610.014
negative regulation of transferase activityGO:00513481240.014
antibacterial humoral responseGO:0019731240.014
nucleoside catabolic processGO:00091644080.014
cellular amino acid metabolic processGO:00065201160.014
cilium morphogenesisGO:0060271750.014
positive regulation of programmed cell deathGO:00430682490.014
oxidation reduction processGO:00551143960.013
sister chromatid segregationGO:0000819540.013
regulation of establishment of protein localizationGO:00702012420.013
establishment of nucleus localizationGO:004002310.013
endodermal cell fate commitmentGO:000171140.013
system processGO:00030083490.013
circulatory system developmentGO:00723592620.013
single organism reproductive processGO:0044702980.013
cell cycle arrestGO:0007050710.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.013
maintenance of locationGO:00512351120.013
locomotory behaviorGO:000762610.013
vesicle organizationGO:0016050620.013
maintenance of protein locationGO:0045185570.012
spermatid differentiationGO:004851540.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
adult locomotory behaviorGO:000834410.012
response to hormoneGO:00097251750.012
purine containing compound catabolic processGO:00725234110.012
regulation of immune effector processGO:0002697910.012
negative regulation of jnk cascadeGO:0046329160.012
organelle fusionGO:0048284360.012
developmental maturationGO:0021700280.012
somitogenesisGO:000175620.012
nucleus organizationGO:0006997280.012
regulation of apoptotic signaling pathwayGO:20012331750.012
regenerationGO:003109940.012
response to virusGO:00096151260.012
serine phosphorylation of stat proteinGO:004250140.012
negative regulation of proteasomal protein catabolic processGO:1901799320.012
regulation of cellular response to stressGO:00801352440.012
internal peptidyl lysine acetylationGO:0018393970.012
organelle inheritanceGO:004830820.011
mononuclear cell proliferationGO:0032943710.011
neuron developmentGO:00486661130.011
establishment of protein localization to organelleGO:00725941720.011
engulfment of apoptotic cellGO:004365220.011
peptide metabolic processGO:0006518510.011
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.011
oogenesisGO:004847720.011
response to tumor necrosis factorGO:0034612760.011
regulation of g1 s transition of mitotic cell cycleGO:2000045400.011
chromatin organizationGO:00063253510.011
negative regulation of cell developmentGO:0010721480.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
positive regulation of t cell cytokine productionGO:000272640.011
regulation of dendrite morphogenesisGO:0048814110.011
regulation of heart growthGO:006042040.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
positive regulation of nucleotide metabolic processGO:00459812300.011
protein depolymerizationGO:0051261300.011
developmental process involved in reproductionGO:0003006660.011
central nervous system developmentGO:00074171230.011
microtubule depolymerizationGO:0007019180.011
chromosome segregationGO:00070591140.011
neuron deathGO:0070997650.011
negative regulation of cardiac muscle cell proliferationGO:006004420.011
eosinophil activationGO:004330730.011
negative regulation of cellular component organizationGO:00511292350.011
positive regulation of cell cycleGO:00457871400.010
hormone mediated signaling pathwayGO:0009755220.010
regulation of intracellular transportGO:00323861950.010
tripartite regional subdivisionGO:000735120.010
golgi vesicle transportGO:0048193800.010
protein localization to mitochondrionGO:0070585250.010
nucleoside triphosphate metabolic processGO:00091414220.010
lipid transportGO:0006869900.010
purine ribonucleoside triphosphate catabolic processGO:00092073910.010
regulation of neuron differentiationGO:0045664700.010
regulation of cytoskeleton organizationGO:00514931770.010
generation of precursor metabolites and energyGO:0006091680.010
regulation of transmembrane transportGO:00347621390.010

PPP6C disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.016
nervous system diseaseDOID:8634310.016
eye diseaseDOID:56141490.016
eye and adnexa diseaseDOID:14921500.016
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.012
organ system cancerDOID:00506861640.012
disease of mental healthDOID:150700.011