Homo sapiens

15 known processes

PDHA2

pyruvate dehydrogenase (lipoamide) alpha 2

(Aliases: MGC149517,MGC149518,PDHAL)

PDHA2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular amine metabolic processGO:003324070.167
regulation of cellular amino acid metabolic processGO:000652160.101
cellular amine metabolic processGO:0044106410.091
amine metabolic processGO:0009308440.091
regulation of cellular amine metabolic processGO:0033238110.090
positive regulation of cellular amino acid metabolic processGO:004576430.081
cellular amino acid metabolic processGO:00065201160.078
g protein coupled receptor signaling pathwayGO:00071862070.069
cation transportGO:00068123310.066
regulation of cellular ketone metabolic processGO:0010565500.063
cellular ketone metabolic processGO:0042180800.056
cation transmembrane transportGO:00986552380.053
immune responseGO:00069553070.049
post embryonic developmentGO:000979120.046
inorganic ion transmembrane transportGO:00986602310.041
negative regulation of protein metabolic processGO:00512483910.041
metal ion homeostasisGO:00550651690.039
positive regulation of immune system processGO:00026842830.039
response to other organismGO:00517072610.038
regulation of cell cycleGO:00517263930.038
negative regulation of cell migrationGO:00303361020.037
ion homeostasisGO:00508012300.037
innate immune responseGO:00450871780.037
negative regulation of cellular protein metabolic processGO:00322693530.036
response to abiotic stimulusGO:00096283360.036
cytoplasmic transportGO:00164823790.036
tissue migrationGO:00901301190.035
cellular homeostasisGO:00197251960.035
system processGO:00030083490.035
regulation of ion transportGO:00432691890.035
metal ion transportGO:00300012720.033
positive regulation of transportGO:00510503360.033
negative regulation of catalytic activityGO:00430863350.031
regulation of cell motilityGO:20001452990.031
negative regulation of cell deathGO:00605483450.031
response to biotic stimulusGO:00096072760.030
cellular cation homeostasisGO:00300031630.029
negative regulation of programmed cell deathGO:00430693210.029
ion transmembrane transportGO:00342203380.029
chemical homeostasisGO:00488783060.029
regulation of locomotionGO:00400123290.029
negative regulation of apoptotic processGO:00430663160.028
cellular calcium ion homeostasisGO:00068741170.027
spermatid differentiationGO:004851540.027
actin filament based processGO:00300292240.027
matingGO:000761810.027
response to external biotic stimulusGO:00432072610.026
positive regulation of cytokine productionGO:00018191670.026
transmembrane transportGO:00550853990.026
cation homeostasisGO:00550801890.026
response to oxygen containing compoundGO:19017003690.026
female gamete generationGO:000729220.026
positive regulation of cell proliferationGO:00082843010.026
calcium ion transportGO:00068161470.026
cytosolic calcium ion homeostasisGO:0051480890.026
circulatory system developmentGO:00723592620.025
regulation of cell migrationGO:00303342890.025
cellular chemical homeostasisGO:00550821800.024
protein processingGO:00164852260.024
regulation of cell cycle processGO:00105642660.024
oogenesisGO:004847720.024
monovalent inorganic cation transportGO:00156721280.024
spermatid developmentGO:000728640.024
carbohydrate derivative biosynthetic processGO:19011372070.024
cellular ion homeostasisGO:00068731680.023
oxidation reduction processGO:00551143960.023
divalent metal ion transportGO:00708381520.023
reactive nitrogen species metabolic processGO:200105730.023
protein maturationGO:00516042330.022
purine ribonucleoside metabolic processGO:00461284370.022
epithelium migrationGO:00901321190.022
regulation of ion transmembrane transportGO:00347651320.022
regulation of transferase activityGO:00513383550.022
copulationGO:000762010.022
determination of adult lifespanGO:000834020.022
cellular macromolecule catabolic processGO:00442653800.022
response to lipidGO:00339932060.022
opioid receptor signaling pathwayGO:003800340.021
reactive oxygen species metabolic processGO:0072593750.021
nucleotide biosynthetic processGO:00091651090.021
regulation of establishment of protein localizationGO:00702012420.021
regulation of metal ion transportGO:00109591200.021
multicellular organismal agingGO:001025930.021
negative regulation of cell motilityGO:20001461040.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
cellular response to endogenous stimulusGO:00714953360.021
inorganic cation transmembrane transportGO:00986621940.021
divalent inorganic cation transportGO:00725111580.020
negative regulation of protein modification processGO:00314002000.020
signal transduction by phosphorylationGO:00230142970.020
protein catabolic processGO:00301633250.020
morphogenesis of embryonic epitheliumGO:001633140.020
chromatin organizationGO:00063253510.020
response to growth factorGO:00708482050.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
intracellular protein transportGO:00068862700.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
epithelial cell migrationGO:00106311190.020
cellular protein catabolic processGO:00442572610.020
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathwayGO:003562540.019
organophosphate biosynthetic processGO:00904071630.019
cellular divalent inorganic cation homeostasisGO:00725031280.019
secretionGO:00469032540.019
divalent inorganic cation homeostasisGO:00725071360.019
neurological system processGO:00508771630.019
epidermis morphogenesisGO:004873030.019
neuromuscular junction developmentGO:000752830.019
single organism cellular localizationGO:19025803320.019
chromatin modificationGO:00165682980.019
protein modification by small protein conjugationGO:00324463420.019
rhythmic behaviorGO:000762220.019
cell activationGO:00017752130.019
purine containing compound catabolic processGO:00725234110.019
regulation of cellular component movementGO:00512703340.019
purine nucleoside triphosphate catabolic processGO:00091463920.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
vesicle mediated transportGO:00161923710.019
defense responseGO:00069523150.018
cellular metal ion homeostasisGO:00068751460.018
regulation of cell growthGO:00015581350.018
negative regulation of phosphorus metabolic processGO:00105632670.018
ribonucleotide catabolic processGO:00092614050.018
nucleoside phosphate biosynthetic processGO:19012931090.018
neuropeptide signaling pathwayGO:0007218190.018
negative regulation of cellular component movementGO:00512711060.018
purine ribonucleotide biosynthetic processGO:0009152790.018
positive regulation of nucleotide metabolic processGO:00459812300.018
regulation of protein localizationGO:00328802960.018
positive regulation of cytosolic calcium ion concentrationGO:0007204820.018
ribose phosphate biosynthetic processGO:0046390820.018
response to virusGO:00096151260.018
regulation of keratinocyte migrationGO:005154740.018
nucleoside monophosphate metabolic processGO:00091231910.017
single organism membrane organizationGO:00448022680.017
calcium ion homeostasisGO:00550741220.017
purine nucleotide biosynthetic processGO:0006164840.017
purine ribonucleoside monophosphate catabolic processGO:00091691580.017
ameboidal type cell migrationGO:00016671350.017
protein acetylationGO:00064731160.017
secretion by cellGO:00329402260.017
inseminationGO:000732010.017
reproductive processGO:00224141060.017
positive regulation of cell cycleGO:00457871400.017
actin filament based movementGO:0030048170.017
rna processingGO:00063962550.017
cellular response to oxygen containing compoundGO:19017012760.017
ribonucleotide biosynthetic processGO:0009260810.017
positive regulation of cellular component organizationGO:00511303760.017
regulation of immune responseGO:00507762010.017
positive regulation of locomotionGO:00400171860.017
nitrogen compound transportGO:00717051910.017
organonitrogen compound biosynthetic processGO:19015662000.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
segmentationGO:003528240.017
purine nucleotide catabolic processGO:00061954050.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of protein maturationGO:19033171500.016
cell cycle phase transitionGO:00447701730.016
response to bacteriumGO:00096171440.016
regenerationGO:003109940.016
organelle assemblyGO:00709251760.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
purine nucleoside catabolic processGO:00061523980.016
mitotic cell cycle processGO:19030472860.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
peptidyl tyrosine modificationGO:00182121700.016
negative regulation of phosphate metabolic processGO:00459362670.016
negative regulation of cytosolic calcium ion concentrationGO:005148110.016
cellular potassium ion transportGO:0071804600.016
peptidyl tyrosine phosphorylationGO:00181081700.016
actin mediated cell contractionGO:0070252120.016
blastoderm segmentationGO:000735020.016
cell growthGO:00160491600.016
nucleotide catabolic processGO:00091664080.016
membrane organizationGO:00610242920.016
small gtpase mediated signal transductionGO:0007264780.016
negative regulation of multicellular organismal processGO:00512413170.016
nucleoside monophosphate catabolic processGO:00091251590.016
regulation of circadian sleep wake cycleGO:004274920.016
actin cytoskeleton organizationGO:00300362070.016
regulation of protein kinase activityGO:00458592890.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
negative regulation of locomotionGO:00400131180.016
cellular macromolecular complex assemblyGO:00346223240.016
proteolysis involved in cellular protein catabolic processGO:00516032440.015
cyclic nucleotide metabolic processGO:0009187820.015
cyclic nucleotide biosynthetic processGO:0009190610.015
ribonucleoside catabolic processGO:00424544060.015
sequestering of metal ionGO:0051238240.015
regulation of transmembrane transportGO:00347621390.015
serotonin transportGO:000683730.015
cellular lipid metabolic processGO:00442553030.015
atp metabolic processGO:00460341760.015
cell developmentGO:00484683280.015
sleepGO:003043120.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
positive regulation of secretion by cellGO:19035321080.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
negative regulation of transportGO:00510511760.015
regulation of erk1 and erk2 cascadeGO:0070372990.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
mapk cascadeGO:00001652880.015
cell divisionGO:00513011680.015
regulation of protein transportGO:00512232130.015
response to nitrogen compoundGO:19016981840.015
regulation of intracellular transportGO:00323861950.015
ribonucleoside triphosphate metabolic processGO:00091994120.015
regulation of proteolysisGO:00301622930.015
single organism reproductive processGO:0044702980.015
anterior posterior axis specificationGO:000994820.014
glycosyl compound catabolic processGO:19016584130.014
positive regulation of phosphorylationGO:00423273940.014
negative regulation of hydrolase activityGO:00513461820.014
epithelial cell differentiationGO:00308551410.014
organophosphate catabolic processGO:00464344300.014
maintenance of locationGO:00512351120.014
protein ubiquitinationGO:00165673140.014
sensory perception of painGO:001923340.014
positive regulation of cell motilityGO:20001471770.014
regulation of anatomical structure morphogenesisGO:00226032860.014
nervous system developmentGO:00073992930.014
response to hypoxiaGO:0001666960.014
nucleoside triphosphate catabolic processGO:00091433940.014
nucleoside triphosphate metabolic processGO:00091414220.014
cellular response to nitrogen compoundGO:19016991440.014
response to hormoneGO:00097251750.014
mitotic cell cycleGO:00002783260.014
purine containing compound biosynthetic processGO:0072522880.014
regulation of cytokine productionGO:00018172320.014
angiogenesisGO:00015251470.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
regulation of secretionGO:00510461940.014
cell morphogenesisGO:00009022960.014
muscle contractionGO:0006936730.014
memoryGO:000761330.014
response to woundingGO:00096111680.014
positive regulation of immune responseGO:00507781590.013
blood circulationGO:00080151130.013
negative regulation of intracellular signal transductionGO:19025321830.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
growthGO:00400072020.013
ras protein signal transductionGO:0007265730.013
negative regulation of wnt protein secretionGO:006135810.013
regulation of nucleotide metabolic processGO:00061402690.013
protein acylationGO:00435431380.013
epithelium developmentGO:00604292270.013
vasodilationGO:004231140.013
nucleoside catabolic processGO:00091644080.013
oocyte developmentGO:004859910.013
purine ribonucleoside catabolic processGO:00461303980.013
negative regulation of cellular component organizationGO:00511292350.013
negative regulation of phosphorylationGO:00423261740.013
sequestering of calcium ionGO:0051208170.013
circadian behaviorGO:004851220.013
protein oligomerizationGO:00512591730.013
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.013
cellular response to organic cyclic compoundGO:00714071270.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
central nervous system developmentGO:00074171230.013
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.013
protein localization to organelleGO:00333652800.013
regulation of cell divisionGO:00513021160.013
regulation of protein processingGO:00706131500.013
regulation of meiotic cell cycleGO:005144540.013
regulation of cellular response to stressGO:00801352440.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
mitotic cell cycle phase transitionGO:00447721620.013
response to organic cyclic compoundGO:00140702040.013
organelle fissionGO:00482851490.013
immune system developmentGO:00025201950.012
atp catabolic processGO:00062001570.012
response to oxygen levelsGO:00704821000.012
biological adhesionGO:00226103310.012
cellular response to organonitrogen compoundGO:00714171240.012
response to activityGO:001482300.012
cellular response to growth factor stimulusGO:00713631970.012
cellular response to abiotic stimulusGO:00712141170.012
associative learningGO:000830610.012
protein targetingGO:00066051870.012
immune effector processGO:00022521590.012
ureteric bud elongationGO:006067720.012
covalent chromatin modificationGO:00165692540.012
cellular component morphogenesisGO:00329893140.012
muscle system processGO:0003012810.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
oocyte differentiationGO:000999420.012
lipid metabolic processGO:00066293810.012
negative regulation of cellular amine metabolic processGO:003323930.012
purine ribonucleotide catabolic processGO:00091544040.012
regulation of purine nucleotide metabolic processGO:19005422640.012
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163510.012
cell projection organizationGO:00300302520.012
regulation of secretion by cellGO:19035301770.012
lung alveolus developmentGO:004828640.012
cellular response to dna damage stimulusGO:00069743790.012
embryonic epithelial tube formationGO:000183840.012
positive regulation of cellular catabolic processGO:00313312840.012
positive regulation of cellular component movementGO:00512721810.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
anterior posterior axis specification embryoGO:000859520.012
regulation of growthGO:00400081650.012
receptor transactivationGO:003562440.012
regulation of cell differentiationGO:00455953930.012
axis elongationGO:000340140.012
positive regulation of cell cycle processGO:00900681060.012
regulation of kinase activityGO:00435493140.012
proteasomal protein catabolic processGO:00104981760.012
carbohydrate metabolic processGO:00059752070.012
positive regulation of synaptic transmissionGO:005080640.012
regulation of cell adhesionGO:00301551660.012
regulation of response to external stimulusGO:00321012220.012
tripartite regional subdivisionGO:000735120.012
nuclear transportGO:00511691790.012
negative regulation of protein phosphorylationGO:00019331400.012
peptidyl serine modificationGO:00182091060.012
ubiquitin dependent protein catabolic processGO:00065112060.012
microtubule based processGO:00070172100.012
apoptotic signaling pathwayGO:00971902680.012
single organism carbohydrate metabolic processGO:00447231930.012
negative regulation of growthGO:0045926970.012
cell substrate adhesionGO:00315891320.011
syncytium formation by plasma membrane fusionGO:000076820.011
positive regulation of hydrolase activityGO:00513453310.011
response to axon injuryGO:004867810.011
histone modificationGO:00165702510.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
response to lipopolysaccharideGO:0032496700.011
cardiac muscle cell contractionGO:008600340.011
cellular response to toxic substanceGO:009723740.011
modification dependent protein catabolic processGO:00199412090.011
positive regulation of catabolic processGO:00098963100.011
nucleoside phosphate catabolic processGO:19012924120.011
regulation of lymphocyte activationGO:00512491030.011
posttranscriptional regulation of gene expressionGO:00106082130.011
regulation of calcium ion transportGO:0051924790.011
negative regulation of developmental processGO:00510932470.011
dna repairGO:00062811980.011
nuclear divisionGO:00002801280.011
striated muscle contractionGO:0006941520.011
detection of chemical stimulus involved in sensory perceptionGO:0050907330.011
cardiovascular system developmentGO:00723582620.011
response to organonitrogen compoundGO:00102431560.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of mapk cascadeGO:00434082620.011
blood vessel developmentGO:00015681720.011
meiosis iGO:000712740.011
sulfur compound metabolic processGO:00067901010.011
vasculature developmentGO:00019441810.011
regulation of system processGO:00440571010.011
negative regulation of protein processingGO:00109551420.011
regulation of protein secretionGO:0050708860.011
modification dependent macromolecule catabolic processGO:00436322120.011
regulation of protein complex assemblyGO:00432541470.011
negative regulation of transferase activityGO:00513481240.011
negative regulation of synaptic transmissionGO:005080520.011
negative regulation of cell proliferationGO:00082852280.011
anatomical structure homeostasisGO:00602491000.011
response to disaccharideGO:003428510.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
locomotory behaviorGO:000762610.011
cyclic purine nucleotide metabolic processGO:0052652600.011
plasma membrane organizationGO:00070091150.011
cell adhesionGO:00071553250.011
negative regulation of cell cycleGO:00457861930.011
peripheral nervous system developmentGO:000742220.011
dephosphorylationGO:00163112090.011
sensory perception of smellGO:000760820.010
positive regulation of cell migrationGO:00303351720.010
positive regulation of apoptotic processGO:00430652460.010
lipid transportGO:0006869900.010
positive regulation of transmembrane transportGO:0034764410.010
cellular protein complex assemblyGO:00436231880.010
organ formationGO:004864530.010
tissue homeostasisGO:0001894630.010
detection of chemical stimulus involved in sensory perception of smellGO:005091120.010
cytokine productionGO:00018162470.010
positive regulation of nucleotide biosynthetic processGO:0030810380.010
regulation of endopeptidase activityGO:00525481700.010
single organism cell adhesionGO:00986021790.010
endomembrane system organizationGO:00102561960.010
microtubule cytoskeleton organizationGO:00002261760.010

PDHA2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.045
sensory system diseaseDOID:00501552030.045
eye diseaseDOID:56141490.022
eye and adnexa diseaseDOID:14921500.022
musculoskeletal system diseaseDOID:172230.021
retinal diseaseDOID:56791180.020
disease of cellular proliferationDOID:145661740.014
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
disease of metabolismDOID:00146672950.013
retinal degenerationDOID:8466890.012
immune system diseaseDOID:29141550.011
cardiovascular system diseaseDOID:12871060.011
muscular diseaseDOID:00800001140.011
muscle tissue diseaseDOID:661130.011
myopathyDOID:4231040.011
central nervous system diseaseDOID:3311860.010