Homo sapiens

0 known processes

LEAP2

liver expressed antimicrobial peptide 2

(Aliases: LEAP-2)

LEAP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.063
cellular amino acid metabolic processGO:00065201160.060
cellular ketone metabolic processGO:0042180800.053
amine metabolic processGO:0009308440.047
regulation of cellular amino acid metabolic processGO:000652160.044
cellular amine metabolic processGO:0044106410.044
regulation of cellular amine metabolic processGO:0033238110.043
regulation of cellular ketone metabolic processGO:0010565500.043
multicellular organismal agingGO:001025930.040
determination of adult lifespanGO:000834020.039
positive regulation of cellular amino acid metabolic processGO:004576430.037
positive regulation of cellular amine metabolic processGO:003324070.036
lipid metabolic processGO:00066293810.035
locomotory behaviorGO:000762610.033
female gamete generationGO:000729220.032
purine ribonucleoside metabolic processGO:00461284370.031
negative regulation of protein metabolic processGO:00512483910.030
organophosphate catabolic processGO:00464344300.030
purine containing compound catabolic processGO:00725234110.029
transmembrane transportGO:00550853990.029
nucleoside triphosphate metabolic processGO:00091414220.029
oogenesisGO:004847720.029
purine nucleoside triphosphate metabolic processGO:00091444120.028
system processGO:00030083490.028
negative regulation of catalytic activityGO:00430863350.028
nucleoside phosphate catabolic processGO:19012924120.028
ras protein signal transductionGO:0007265730.028
negative regulation of cellular protein metabolic processGO:00322693530.028
glycosyl compound catabolic processGO:19016584130.028
nucleotide catabolic processGO:00091664080.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
ribonucleoside triphosphate metabolic processGO:00091994120.028
cellular lipid metabolic processGO:00442553030.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
purine nucleotide catabolic processGO:00061954050.027
ribonucleoside catabolic processGO:00424544060.027
ribonucleotide catabolic processGO:00092614050.027
purine nucleoside catabolic processGO:00061523980.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
small gtpase mediated signal transductionGO:0007264780.026
purine ribonucleoside catabolic processGO:00461303980.026
segmentationGO:003528240.026
cytoplasmic transportGO:00164823790.026
purine ribonucleotide catabolic processGO:00091544040.026
nucleoside triphosphate catabolic processGO:00091433940.025
positive regulation of hydrolase activityGO:00513453310.025
positive regulation of transportGO:00510503360.025
immune responseGO:00069553070.025
cation transportGO:00068123310.025
nucleoside catabolic processGO:00091644080.025
regenerationGO:003109940.025
positive regulation of catabolic processGO:00098963100.025
cellular macromolecule catabolic processGO:00442653800.024
positive regulation of phosphorylationGO:00423273940.024
neuromuscular junction developmentGO:000752830.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
regulation of cell differentiationGO:00455953930.024
response to oxygen containing compoundGO:19017003690.024
oxidation reduction processGO:00551143960.024
positive regulation of cellular component organizationGO:00511303760.024
regulation of cell cycleGO:00517263930.024
actin filament based processGO:00300292240.023
response to abiotic stimulusGO:00096283360.023
regulation of transferase activityGO:00513383550.023
protein catabolic processGO:00301633250.023
chemical homeostasisGO:00488783060.023
single organism cellular localizationGO:19025803320.022
ion transmembrane transportGO:00342203380.022
negative regulation of phosphorus metabolic processGO:00105632670.022
regulation of protein localizationGO:00328802960.022
negative regulation of cell deathGO:00605483450.022
memoryGO:000761330.022
defense responseGO:00069523150.022
rho protein signal transductionGO:0007266260.022
negative regulation of phosphate metabolic processGO:00459362670.022
protein maturationGO:00516042330.022
positive regulation of cellular catabolic processGO:00313312840.022
protein localization to organelleGO:00333652800.021
negative regulation of programmed cell deathGO:00430693210.021
regulation of proteolysisGO:00301622930.021
monocarboxylic acid metabolic processGO:00327871850.021
single organism membrane organizationGO:00448022680.021
negative regulation of cellular amine metabolic processGO:003323930.021
mitotic cell cycleGO:00002783260.021
cellular response to dna damage stimulusGO:00069743790.021
metal ion transportGO:00300012720.021
cell morphogenesisGO:00009022960.021
regulation of kinase activityGO:00435493140.021
negative regulation of multicellular organismal processGO:00512413170.020
negative regulation of apoptotic processGO:00430663160.020
carbohydrate metabolic processGO:00059752070.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
membrane organizationGO:00610242920.020
regulation of cellular component movementGO:00512703340.020
biological adhesionGO:00226103310.020
small molecule biosynthetic processGO:00442831570.020
anterior posterior axis specificationGO:000994820.020
blastoderm segmentationGO:000735020.020
cation transmembrane transportGO:00986552380.020
adult locomotory behaviorGO:000834410.020
regulation of protein kinase activityGO:00458592890.020
regulation of nucleotide metabolic processGO:00061402690.020
cellular component morphogenesisGO:00329893140.020
protein processingGO:00164852260.020
hindbrain developmentGO:003090230.020
regulation of cell cycle processGO:00105642660.019
dephosphorylationGO:00163112090.019
cell adhesionGO:00071553250.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of establishment of protein localizationGO:00702012420.019
carbohydrate derivative biosynthetic processGO:19011372070.019
organonitrogen compound biosynthetic processGO:19015662000.019
intracellular protein transportGO:00068862700.019
release of cytoplasmic sequestered nf kappabGO:000858840.019
vesicle mediated transportGO:00161923710.019
morphogenesis of embryonic epitheliumGO:001633140.019
lipid biosynthetic processGO:00086101770.019
positive regulation of cell deathGO:00109422630.019
cellular protein catabolic processGO:00442572610.019
anion transportGO:00068201610.019
regulation of cellular response to stressGO:00801352440.019
regulation of purine nucleotide metabolic processGO:19005422640.019
cellular response to endogenous stimulusGO:00714953360.019
apoptotic signaling pathwayGO:00971902680.019
positive regulation of protein phosphorylationGO:00019343130.019
cardiac muscle cell contractionGO:008600340.019
ion homeostasisGO:00508012300.019
inorganic ion transmembrane transportGO:00986602310.018
single organism carbohydrate metabolic processGO:00447231930.018
signal transduction by phosphorylationGO:00230142970.018
regulation of response to external stimulusGO:00321012220.018
positive regulation of apoptotic processGO:00430652460.018
positive regulation of immune system processGO:00026842830.018
positive regulation of cell proliferationGO:00082843010.018
regulation of anatomical structure morphogenesisGO:00226032860.018
regulation of cell motilityGO:20001452990.018
protein modification by small protein conjugationGO:00324463420.018
peripheral nervous system developmentGO:000742220.018
nervous system developmentGO:00073992930.018
cell projection organizationGO:00300302520.018
nitrogen compound transportGO:00717051910.018
spermatid differentiationGO:004851540.018
positive regulation of nucleotide metabolic processGO:00459812300.018
secretionGO:00469032540.018
cellular response to oxygen containing compoundGO:19017012760.018
cell developmentGO:00484683280.018
mapk cascadeGO:00001652880.018
cell fate determinationGO:000170930.018
reactive nitrogen species metabolic processGO:200105730.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
oocyte developmentGO:004859910.018
guanosine containing compound catabolic processGO:19010692390.018
regulation of locomotionGO:00400123290.017
reactive oxygen species biosynthetic processGO:190340940.017
positive regulation of programmed cell deathGO:00430682490.017
mitotic cell cycle processGO:19030472860.017
regulation of protein transportGO:00512232130.017
innate immune responseGO:00450871780.017
rhythmic behaviorGO:000762220.017
oocyte differentiationGO:000999420.017
inner ear morphogenesisGO:004247240.017
regulation of cellular component biogenesisGO:00440872810.017
maintenance of locationGO:00512351120.017
posttranscriptional regulation of gene expressionGO:00106082130.017
negative regulation of hydrolase activityGO:00513461820.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
chromatin organizationGO:00063253510.017
motor neuron axon guidanceGO:000804520.017
regulation of purine nucleotide catabolic processGO:00331212050.017
photoreceptor cell differentiationGO:004653020.017
negative regulation of protein modification processGO:00314002000.017
negative regulation of cellular component organizationGO:00511292350.017
protein ubiquitinationGO:00165673140.017
guanosine containing compound metabolic processGO:19010682440.017
gtp metabolic processGO:00460392390.017
inorganic cation transmembrane transportGO:00986621940.017
response to external biotic stimulusGO:00432072610.016
regulation of synaptic plasticityGO:004816730.016
negative regulation of cell proliferationGO:00082852280.016
embryonic epithelial tube formationGO:000183840.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of developmental processGO:00510943140.016
neurotransmitter secretionGO:000726940.016
positive regulation of synaptic transmissionGO:005080640.016
organ formationGO:004864530.016
regulation of cell migrationGO:00303342890.016
circadian behaviorGO:004851220.016
regulation of nucleoside metabolic processGO:00091182090.016
compound eye developmentGO:004874910.016
protein targetingGO:00066051870.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
secretion by cellGO:00329402260.016
response to biotic stimulusGO:00096072760.016
histone modificationGO:00165702510.016
regulation of intracellular transportGO:00323861950.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
response to cytokineGO:00340972320.016
regulation of mapk cascadeGO:00434082620.016
associative learningGO:000830610.016
gtp catabolic processGO:00061842370.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
regulation of secretionGO:00510461940.016
response to other organismGO:00517072610.016
positive regulation of nucleoside metabolic processGO:00459791860.016
spermatid developmentGO:000728640.016
positive regulation of transferase activityGO:00513472270.015
cation homeostasisGO:00550801890.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
regulation of nucleotide catabolic processGO:00308112050.015
nerve developmentGO:002167540.015
neuroblast proliferationGO:000740540.015
cellular homeostasisGO:00197251960.015
neurological system processGO:00508771630.015
regulation of cytokine productionGO:00018172320.015
chromatin modificationGO:00165682980.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
tripartite regional subdivisionGO:000735120.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
reactive oxygen species metabolic processGO:0072593750.015
modification dependent macromolecule catabolic processGO:00436322120.015
negative regulation of developmental processGO:00510932470.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
regulation of neural precursor cell proliferationGO:200017740.015
carboxylic acid biosynthetic processGO:0046394970.015
negative regulation of cell cycleGO:00457861930.015
sensory perception of smellGO:000760820.015
anterior posterior axis specification embryoGO:000859520.015
actin mediated cell contractionGO:0070252120.015
organic hydroxy compound metabolic processGO:19016151470.015
salivary gland morphogenesisGO:000743540.015
organic acid biosynthetic processGO:0016053970.015
cytokine productionGO:00018162470.015
actin filament based movementGO:0030048170.015
morphogenesis of a polarized epitheliumGO:000173830.015
regulation of immune responseGO:00507762010.015
microtubule based processGO:00070172100.015
covalent chromatin modificationGO:00165692540.015
organophosphate biosynthetic processGO:00904071630.015
metencephalon developmentGO:002203720.015
regulation of meiotic cell cycleGO:005144540.015
atp metabolic processGO:00460341760.015
positive regulation of nucleotide catabolic processGO:00308131850.015
visual behaviorGO:000763220.015
mitochondrion organizationGO:00070051560.015
rna processingGO:00063962550.014
cellular protein complex assemblyGO:00436231880.014
specification of organ identityGO:001009230.014
nucleoside monophosphate metabolic processGO:00091231910.014
response to fungusGO:000962040.014
cellular response to cytokine stimulusGO:00713451810.014
tissue regenerationGO:004224630.014
negative regulation of phosphorylationGO:00423261740.014
spinal cord developmentGO:002151040.014
endomembrane system organizationGO:00102561960.014
modification dependent protein catabolic processGO:00199412090.014
regulation of protein maturationGO:19033171500.014
epithelium developmentGO:00604292270.014
positive regulation of organelle organizationGO:00106381950.014
organic anion transportGO:00157111030.014
rna interferenceGO:001624640.014
regulation of endopeptidase activityGO:00525481700.014
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.014
response to lipidGO:00339932060.014
response to organic cyclic compoundGO:00140702040.014
syncytium formation by plasma membrane fusionGO:000076820.014
regulation of protein catabolic processGO:00421761550.014
response to axon injuryGO:004867810.014
regulation of gtpase activityGO:00430871800.014
proteasomal protein catabolic processGO:00104981760.014
growthGO:00400072020.014
regulation of protein processingGO:00706131500.014
protein oligomerizationGO:00512591730.014
regulation of peptidase activityGO:00525471800.014
ubiquitin dependent protein catabolic processGO:00065112060.014
actin cytoskeleton organizationGO:00300362070.014
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.014
regulation of transcription during mitosisGO:004589620.014
organelle assemblyGO:00709251760.014
cell growthGO:00160491600.014
positive regulation of cell differentiationGO:00455972110.014
cellular chemical homeostasisGO:00550821800.014
9 cis retinoic acid metabolic processGO:004290510.014
negative regulation of transportGO:00510511760.014
nuclear transportGO:00511691790.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
positive regulation of cellular component movementGO:00512721810.014
matingGO:000761810.013
positive regulation of kinase activityGO:00336742040.013
regulation of gtp catabolic processGO:00331241800.013
limbic system developmentGO:002176130.013
fatty acid metabolic processGO:00066311150.013
stem cell divisionGO:001714520.013
sex determinationGO:000753030.013
regulation of mitotic cell cycleGO:00073461890.013
establishment of protein localization to organelleGO:00725941720.013
glycoprotein metabolic processGO:00091001100.013
cellular cation homeostasisGO:00300031630.013
regulation of secretion by cellGO:19035301770.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
cell cycle phase transitionGO:00447701730.013
regulation of cytoskeleton organizationGO:00514931770.013
positive regulation of gtpase activityGO:00435471660.013
response to nitrogen compoundGO:19016981840.013
metal ion homeostasisGO:00550651690.013
circulatory system developmentGO:00723592620.013
positive regulation of protein kinase activityGO:00458601900.013
protein localization to membraneGO:00726571600.013
sequestering of metal ionGO:0051238240.013
negative regulation of protein processingGO:00109551420.013
interspecies interaction between organismsGO:00444191560.013
multi organism cellular processGO:00447641560.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
sodium independent organic anion transportGO:004325220.013
nucleocytoplasmic transportGO:00069131760.013
cofactor metabolic processGO:0051186870.013
dna repairGO:00062811980.013
neural tube formationGO:000184130.013
positive regulation of gtp catabolic processGO:00331261660.013
positive regulation of transcription during mitosisGO:004589720.013
sulfur compound metabolic processGO:00067901010.013
positive regulation of cell migrationGO:00303351720.013
cardiovascular system developmentGO:00723582620.013
thymus developmentGO:004853830.013
divalent inorganic cation transportGO:00725111580.013
regulation of ras protein signal transductionGO:00465781550.013
forebrain generation of neuronsGO:002187230.013
regulation of apoptotic signaling pathwayGO:20012331750.013
positive regulation of protein transportGO:00512221350.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
cell divisionGO:00513011680.013
regulation of cytoplasmic transportGO:19036491490.012
wnt signaling pathwayGO:00160551560.012
somitogenesisGO:000175620.012
startle responseGO:000196430.012
divalent metal ion transportGO:00708381520.012
regulation of neurotransmitter secretionGO:004692830.012
long term memoryGO:000761620.012
cerebellum developmentGO:002154920.012
negative regulation of protein maturationGO:19033181420.012
myoblast fusionGO:000752010.012
nucleoside monophosphate catabolic processGO:00091251590.012
positive regulation of locomotionGO:00400171860.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
cellular response to growth factor stimulusGO:00713631970.012
cell activationGO:00017752130.012
regulation of ion transportGO:00432691890.012
sequestering of calcium ionGO:0051208170.012
positive regulation of cellular component biogenesisGO:00440891580.012
positive regulation of cell motilityGO:20001471770.012
positive regulation of mapk cascadeGO:00434101900.012
regulation of growthGO:00400081650.012
regulation of multi organism processGO:00439001570.012
regulation of dna metabolic processGO:00510521530.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
establishment of planar polarityGO:000173630.012
peptidyl tyrosine modificationGO:00182121700.012
alcohol metabolic processGO:00060661140.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
negative regulation of transferase activityGO:00513481240.012
response to growth factorGO:00708482050.012
i kappab kinase nf kappab signalingGO:00072491660.012
negative regulation of proteolysisGO:00458611320.012
regulation of ras gtpase activityGO:00323181280.012
cell projection assemblyGO:00300311260.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
negative regulation of protein phosphorylationGO:00019331400.012
forelimb morphogenesisGO:003513640.012
tube closureGO:006060630.012
positive regulation of secretionGO:00510471160.012
peptidyl tyrosine phosphorylationGO:00181081700.012
regulation of protein serine threonine kinase activityGO:00719001790.012
small molecule catabolic processGO:0044282920.012
primary neural tube formationGO:001402030.012
microtubule cytoskeleton organizationGO:00002261760.012
response to woundingGO:00096111680.012
sensory perception of painGO:001923340.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
regulation of cell adhesionGO:00301551660.012
lung alveolus developmentGO:004828640.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
monovalent inorganic cation transportGO:00156721280.012
somatic stem cell maintenanceGO:003501940.012
glial cell migrationGO:000834740.012
response to hormoneGO:00097251750.012
atp catabolic processGO:00062001570.012
regulation of cell growthGO:00015581350.012
sleepGO:003043120.012
calcium ion transportGO:00068161470.012
cellular metal ion homeostasisGO:00068751460.012
developmental programmed cell deathGO:001062330.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
single organism cell adhesionGO:00986021790.012
visual learningGO:000854210.012
protein acylationGO:00435431380.012
mitotic cell cycle phase transitionGO:00447721620.012
response to radiationGO:00093141510.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
positive regulation of cytokine productionGO:00018191670.011
positive regulation of immune responseGO:00507781590.011
cranial nerve developmentGO:002154540.011
t cell differentiation in thymusGO:003307740.011
peptidyl lysine modificationGO:00182051440.011
immune system developmentGO:00025201950.011
regulation of intracellular protein transportGO:00331571230.011
epidermis morphogenesisGO:004873030.011
male genitalia developmentGO:003053910.011
regulation of hormone levelsGO:00108171250.011
post embryonic organ developmentGO:004856910.011
somatic stem cell divisionGO:004810310.011
regulation of defense responseGO:00313471540.011
establishment of protein localization to membraneGO:00901501210.011
regulation of cell morphogenesisGO:00226041530.011
viral processGO:00160321460.011
defense response to fungusGO:005083240.011
neurogenesisGO:00220081690.011
cellular ion homeostasisGO:00068731680.011
divalent inorganic cation homeostasisGO:00725071360.011
coenzyme metabolic processGO:0006732650.011
somatic muscle developmentGO:000752510.011
meiotic chromosome segregationGO:004513240.011
cell part morphogenesisGO:00329901370.011
neural tube closureGO:000184330.011
sensory perceptionGO:00076001030.011
negative regulation of organelle organizationGO:00106391260.011
heart formationGO:006091420.011
regulation of vesicle mediated transportGO:00606271300.011
positive regulation of neural precursor cell proliferationGO:200017920.011
establishment of tissue polarityGO:000716430.011
viral life cycleGO:00190581320.011
cdc42 protein signal transductionGO:003248840.011
endosomal transportGO:00161971290.011
regulation of glial cell differentiationGO:004568530.011
negative regulation of cell differentiationGO:00455961710.011
protein localization to nucleusGO:00345041360.011
pituitary gland developmentGO:002198320.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
mrna metabolic processGO:00160711750.011
hemopoiesisGO:00300971800.011
meiosis iGO:000712740.011
regulation of meiosisGO:004002030.011
immune effector processGO:00022521590.011
cell substrate adhesionGO:00315891320.011
neural crest cell developmentGO:001403230.011
lipid transportGO:0006869900.011
synaptic vesicle recyclingGO:003646530.011
engulfment of apoptotic cellGO:004365220.011
neuron fate commitmentGO:004866320.011
epithelial tube branching involved in lung morphogenesisGO:006044140.011
regulation of wnt signaling pathwayGO:00301111230.011
forebrain neuron differentiationGO:002187930.011
response to activityGO:001482300.011
axon regenerationGO:003110310.011
regulation of protein complex assemblyGO:00432541470.011
lens development in camera type eyeGO:000208820.011
regulation of cell developmentGO:00602841610.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
multicellular organismal response to stressGO:003355510.011
rna splicingGO:00083801310.011
striated muscle contractionGO:0006941520.011
response to organonitrogen compoundGO:00102431560.011
embryonic placenta developmentGO:000189210.010
striated muscle myosin thick filament assemblyGO:007168820.010
myosin filament assemblyGO:003103420.010

LEAP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.039
inherited metabolic disorderDOID:6552420.032
musculoskeletal system diseaseDOID:172230.028
sensory system diseaseDOID:00501552030.027
nervous system diseaseDOID:8634310.027
central nervous system diseaseDOID:3311860.022
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.021
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.020
organ system cancerDOID:00506861640.019
immune system diseaseDOID:29141550.018
connective tissue diseaseDOID:651090.017
cardiovascular system diseaseDOID:12871060.017
muscle tissue diseaseDOID:661130.017
muscular diseaseDOID:00800001140.017
retinal diseaseDOID:56791180.016
bone diseaseDOID:0080001880.016
amino acid metabolic disorderDOID:9252500.015
myopathyDOID:4231040.015
neurodegenerative diseaseDOID:12891020.015
hematopoietic system diseaseDOID:741000.013
brain diseaseDOID:936730.012
retinal degenerationDOID:8466890.012
heart diseaseDOID:114680.011
disease of mental healthDOID:150700.011
carbohydrate metabolic disorderDOID:2978550.011
bone development diseaseDOID:0080006550.011