Homo sapiens

80 known processes

HIST4H4

histone cluster 4, H4

(Aliases: HIST1H4C,HIST1H4B,HIST1H4A,HIST1H4F,HIST1H4E,HIST1H4D,HIST1H4K,HIST1H4J,HIST1H4I,HIST1H4H,HIST1H4L,H4/p,MGC24116,HIST2H4B,HIST2H4A)

HIST4H4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replication dependent nucleosome assemblyGO:0006335320.962
chromatin assembly or disassemblyGO:0006333780.846
chromatin organizationGO:00063253510.775
chromatin assemblyGO:0031497610.764
nucleosome assemblyGO:0006334500.700
dna conformation changeGO:00711031130.609
dna replication independent nucleosome assemblyGO:0006336270.596
covalent chromatin modificationGO:00165692540.553
Yeast
protein dna complex assemblyGO:0065004640.516
dna packagingGO:0006323770.469
nucleosome organizationGO:0034728660.465
dna replication dependent nucleosome organizationGO:0034723320.391
dna replication independent nucleosome organizationGO:0034724270.374
histone modificationGO:00165702510.369
Yeast
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.266
Yeast
chromatin modificationGO:00165682980.221
Yeast
protein dna complex subunit organizationGO:0071824800.217
cellular macromolecular complex assemblyGO:00346223240.201
post embryonic developmentGO:000979120.137
regulation of cellular amine metabolic processGO:0033238110.123
cellular amino acid metabolic processGO:00065201160.114
histone methylationGO:0016571600.109
Yeast
peptidyl lysine modificationGO:00182051440.105
methylationGO:00322591060.098
Yeast
cellular ketone metabolic processGO:0042180800.094
amine metabolic processGO:0009308440.091
regulation of cellular ketone metabolic processGO:0010565500.090
macromolecule methylationGO:0043414970.089
Yeast
cellular response to dna damage stimulusGO:00069743790.086
positive regulation of cellular amino acid metabolic processGO:004576430.079
protein ubiquitinationGO:00165673140.077
internal protein amino acid acetylationGO:00064751010.077
protein modification by small protein conjugationGO:00324463420.076
oogenesisGO:004847720.076
positive regulation of cellular amine metabolic processGO:003324070.074
multicellular organismal agingGO:001025930.067
histone acetylationGO:0016573930.063
female gamete generationGO:000729220.062
gene silencingGO:0016458490.060
Yeast
regulation of cell cycleGO:00517263930.055
protein alkylationGO:0008213740.054
Yeast
cellular amine metabolic processGO:0044106410.051
internal peptidyl lysine acetylationGO:0018393970.050
protein catabolic processGO:00301633250.049
regulation of cell growthGO:00015581350.049
negative regulation of developmental processGO:00510932470.048
segmentationGO:003528240.048
protein acylationGO:00435431380.048
negative regulation of multicellular organismal processGO:00512413170.048
determination of adult lifespanGO:000834020.046
peptidyl lysine acetylationGO:00183941010.044
regulation of cellular amino acid metabolic processGO:000652160.044
mitotic cell cycleGO:00002783260.044
protein processingGO:00164852260.044
nervous system developmentGO:00073992930.042
dna repairGO:00062811980.042
positive regulation of organelle organizationGO:00106381950.042
growthGO:00400072020.041
negative regulation of cellular protein metabolic processGO:00322693530.041
cellular macromolecule catabolic processGO:00442653800.041
negative regulation of protein maturationGO:19033181420.039
regulation of cell differentiationGO:00455953930.038
anatomical structure formation involved in morphogenesisGO:00486462840.038
Yeast
negative regulation of protein metabolic processGO:00512483910.038
negative regulation of cell differentiationGO:00455961710.037
regulation of growthGO:00400081650.036
cell morphogenesisGO:00009022960.036
regulation of protein maturationGO:19033171500.036
protein maturationGO:00516042330.035
histone lysine methylationGO:0034968500.033
Yeast
proteolysis involved in cellular protein catabolic processGO:00516032440.032
protein acetylationGO:00064731160.032
ubiquitin dependent protein catabolic processGO:00065112060.032
intracellular protein transportGO:00068862700.031
positive regulation of cellular component organizationGO:00511303760.031
response to abiotic stimulusGO:00096283360.031
cell growthGO:00160491600.031
regulation of proteolysisGO:00301622930.031
cytoplasmic transportGO:00164823790.030
cell projection organizationGO:00300302520.030
regulation of protein processingGO:00706131500.030
negative regulation of catalytic activityGO:00430863350.030
negative regulation of cell deathGO:00605483450.030
rna processingGO:00063962550.029
cellular component morphogenesisGO:00329893140.029
mitotic cell cycle processGO:19030472860.029
regulation of cell cycle processGO:00105642660.029
modification dependent protein catabolic processGO:00199412090.028
single organism cellular localizationGO:19025803320.028
purine ribonucleoside metabolic processGO:00461284370.028
modification dependent macromolecule catabolic processGO:00436322120.028
protein methylationGO:0006479740.028
Yeast
muscle structure developmentGO:0061061980.027
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
immune responseGO:00069553070.027
chromosome segregationGO:00070591140.027
ras protein signal transductionGO:0007265730.027
hematopoietic or lymphoid organ developmentGO:00485341860.027
immune system developmentGO:00025201950.027
positive regulation of phosphorylationGO:00423273940.027
neurogenesisGO:00220081690.027
organophosphate catabolic processGO:00464344300.026
regulation of chromosome organizationGO:00330441030.025
protein localization to organelleGO:00333652800.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
negative regulation of protein processingGO:00109551420.025
negative regulation of programmed cell deathGO:00430693210.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
negative regulation of apoptotic processGO:00430663160.025
cellular response to endogenous stimulusGO:00714953360.025
positive regulation of apoptotic processGO:00430652460.024
apoptotic signaling pathwayGO:00971902680.024
cell developmentGO:00484683280.024
nucleoside phosphate catabolic processGO:19012924120.024
mrna metabolic processGO:00160711750.024
positive regulation of hydrolase activityGO:00513453310.024
regulation of cellular response to stressGO:00801352440.023
negative regulation of phosphorus metabolic processGO:00105632670.023
purine nucleoside triphosphate metabolic processGO:00091444120.023
cellular protein catabolic processGO:00442572610.023
negative regulation of proteolysisGO:00458611320.023
cellular response to oxygen containing compoundGO:19017012760.022
chemical homeostasisGO:00488783060.022
negative regulation of cellular component organizationGO:00511292350.022
proteasomal protein catabolic processGO:00104981760.022
regulation of transferase activityGO:00513383550.022
regulation of peptidase activityGO:00525471800.022
glycosyl compound catabolic processGO:19016584130.022
mitotic cell cycle phase transitionGO:00447721620.022
blastoderm segmentationGO:000735020.022
negative regulation of cell cycleGO:00457861930.021
nucleoside triphosphate catabolic processGO:00091433940.021
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.021
nucleoside triphosphate metabolic processGO:00091414220.021
regulation of protein kinase activityGO:00458592890.021
generation of neuronsGO:00486991520.021
regulation of anatomical structure morphogenesisGO:00226032860.021
positive regulation of cell proliferationGO:00082843010.021
purine nucleotide catabolic processGO:00061954050.021
positive regulation of programmed cell deathGO:00430682490.021
regulation of chromatin organizationGO:1902275560.021
cell adhesionGO:00071553250.020
regenerationGO:003109940.020
cell cycle phase transitionGO:00447701730.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
dna replicationGO:00062601160.020
regulation of protein localizationGO:00328802960.020
regulation of protein catabolic processGO:00421761550.020
myeloid cell differentiationGO:00300991170.020
anterior posterior axis specificationGO:000994820.020
membrane organizationGO:00610242920.020
regulation of mitotic cell cycleGO:00073461890.020
regulation of establishment of protein localizationGO:00702012420.020
posttranscriptional regulation of gene expressionGO:00106082130.020
negative regulation of chromosome organizationGO:2001251480.019
metencephalon developmentGO:002203720.019
positive regulation of cell deathGO:00109422630.019
purine ribonucleotide catabolic processGO:00091544040.019
regulation of kinase activityGO:00435493140.019
ribonucleoside catabolic processGO:00424544060.019
neuromuscular junction developmentGO:000752830.019
cell part morphogenesisGO:00329901370.019
locomotory behaviorGO:000762610.019
cell divisionGO:00513011680.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
regulation of apoptotic signaling pathwayGO:20012331750.019
cellular component disassemblyGO:0022411920.018
carbohydrate derivative biosynthetic processGO:19011372070.018
regulation of cell morphogenesisGO:00226041530.018
biological adhesionGO:00226103310.018
small gtpase mediated signal transductionGO:0007264780.018
regulation of endopeptidase activityGO:00525481700.018
regulation of cellular protein catabolic processGO:1903362960.018
mrna processingGO:00063971330.018
response to hormoneGO:00097251750.018
positive regulation of transportGO:00510503360.018
nucleoside catabolic processGO:00091644080.018
system processGO:00030083490.018
regulation of cell divisionGO:00513021160.018
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of catabolic processGO:00098963100.017
negative regulation of catabolic processGO:00098951040.017
ribonucleotide catabolic processGO:00092614050.017
negative regulation of organelle organizationGO:00106391260.017
purine nucleoside catabolic processGO:00061523980.017
regulation of response to dna damage stimulusGO:2001020940.017
cation transportGO:00068123310.017
regulation of gene silencingGO:0060968240.017
single organism membrane organizationGO:00448022680.017
regulation of mitotic cell cycle phase transitionGO:19019901180.017
regulation of purine nucleotide metabolic processGO:19005422640.017
cell projection morphogenesisGO:00488581290.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
cell morphogenesis involved in differentiationGO:00009041440.016
positive regulation of developmental processGO:00510943140.016
nucleotide catabolic processGO:00091664080.016
neuron projection developmentGO:00311751060.016
dephosphorylationGO:00163112090.016
positive regulation of protein phosphorylationGO:00019343130.016
response to decreased oxygen levelsGO:0036293960.016
purine ribonucleoside catabolic processGO:00461303980.016
cell type specific apoptotic processGO:00972851250.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.016
cranial nerve developmentGO:002154540.016
negative regulation of cell proliferationGO:00082852280.016
cellular response to abiotic stimulusGO:00712141170.016
carbohydrate metabolic processGO:00059752070.016
response to radiationGO:00093141510.016
regulation of gene expression epigeneticGO:0040029730.015
Yeast
negative regulation of cellular catabolic processGO:0031330830.015
reproductive processGO:00224141060.015
Yeast
tripartite regional subdivisionGO:000735120.015
regulation of cellular component biogenesisGO:00440872810.015
regulation of chromatin modificationGO:1903308510.015
oocyte developmentGO:004859910.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of nucleotide metabolic processGO:00459812300.015
regulation of proteasomal protein catabolic processGO:0061136870.015
negative regulation of cell cycle processGO:00109481210.015
purine containing compound catabolic processGO:00725234110.015
actin filament based processGO:00300292240.015
positive regulation of kinase activityGO:00336742040.015
intracellular receptor signaling pathwayGO:00305221040.015
organelle fissionGO:00482851490.015
positive regulation of transferase activityGO:00513472270.015
rna splicingGO:00083801310.015
muscle organ developmentGO:0007517560.015
nitrogen compound transportGO:00717051910.015
response to external biotic stimulusGO:00432072610.014
anterior posterior axis specification embryoGO:000859520.014
response to oxygen containing compoundGO:19017003690.014
positive regulation of protein transportGO:00512221350.014
cellular lipid metabolic processGO:00442553030.014
regulation of nucleotide metabolic processGO:00061402690.014
cellular homeostasisGO:00197251960.014
cellular response to cytokine stimulusGO:00713451810.014
protein targetingGO:00066051870.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
response to other organismGO:00517072610.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
negative regulation of megakaryocyte differentiationGO:0045653160.014
neuron differentiationGO:00301821380.014
negative regulation of protein modification processGO:00314002000.014
response to organic cyclic compoundGO:00140702040.014
positive regulation of cell differentiationGO:00455972110.014
metal ion transportGO:00300012720.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
single organism reproductive processGO:0044702980.014
Yeast
response to woundingGO:00096111680.014
regulation of bindingGO:00510981110.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
maintenance of locationGO:00512351120.014
epithelium developmentGO:00604292270.014
negative regulation of cellular amine metabolic processGO:003323930.014
response to nitrogen compoundGO:19016981840.014
positive regulation of cellular catabolic processGO:00313312840.014
metal ion homeostasisGO:00550651690.014
cellular response to growth factor stimulusGO:00713631970.014
negative regulation of protein catabolic processGO:0042177590.013
vesicle mediated transportGO:00161923710.013
nucleocytoplasmic transportGO:00069131760.013
spermatid differentiationGO:004851540.013
ion homeostasisGO:00508012300.013
embryo developmentGO:00097901230.013
cellular response to nitrogen compoundGO:19016991440.013
regulation of cell developmentGO:00602841610.013
blastocyst developmentGO:000182430.013
negative regulation of hydrolase activityGO:00513461820.013
regulation of secretionGO:00510461940.013
regulation of nuclear divisionGO:0051783650.013
signal transduction by phosphorylationGO:00230142970.013
cellular protein complex assemblyGO:00436231880.013
atp metabolic processGO:00460341760.013
neural crest cell developmentGO:001403230.013
mitotic nuclear divisionGO:00070671190.013
negative regulation of intracellular signal transductionGO:19025321830.013
limbic system developmentGO:002176130.013
signal transduction by p53 class mediatorGO:0072331720.013
negative regulation of cell cycle phase transitionGO:1901988890.013
protein oligomerizationGO:00512591730.013
reactive oxygen species metabolic processGO:0072593750.013
thymus developmentGO:004853830.013
nuclear transportGO:00511691790.013
regulation of locomotionGO:00400123290.013
cation homeostasisGO:00550801890.013
peptidyl tyrosine modificationGO:00182121700.013
regulation of cytokine productionGO:00018172320.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
negative regulation of phosphate metabolic processGO:00459362670.013
glial cell migrationGO:000834740.013
neurological system processGO:00508771630.012
negative regulation of myeloid cell differentiationGO:0045638420.012
positive regulation of chromosome organizationGO:2001252410.012
dna damage checkpointGO:0000077680.012
negative regulation of growthGO:0045926970.012
negative regulation of immune system processGO:00026831360.012
endomembrane system organizationGO:00102561960.012
oocyte differentiationGO:000999420.012
innate immune responseGO:00450871780.012
response to oxygen levelsGO:00704821000.012
secretion by cellGO:00329402260.012
peripheral nervous system developmentGO:000742220.012
oxidation reduction processGO:00551143960.012
spermatid developmentGO:000728640.012
memoryGO:000761330.012
tissue regenerationGO:004224630.012
regulation of cell migrationGO:00303342890.012
negative regulation of phosphorylationGO:00423261740.012
regulation of multi organism processGO:00439001570.012
response to organonitrogen compoundGO:00102431560.012
regulation of mitosisGO:0007088630.012
regulation of cellular component movementGO:00512703340.012
adult locomotory behaviorGO:000834410.012
cardiovascular system developmentGO:00723582620.012
response to hypoxiaGO:0001666960.012
ameboidal type cell migrationGO:00016671350.012
response to growth factorGO:00708482050.012
positive regulation of protein kinase activityGO:00458601900.012
negative regulation of cell growthGO:0030308830.012
negative regulation of cellular protein catabolic processGO:1903363380.012
protein localization to membraneGO:00726571600.012
regulation of nucleoside metabolic processGO:00091182090.012
negative regulation of cell migrationGO:00303361020.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.012
protein complex disassemblyGO:0043241520.012
regulation of cell cycle phase transitionGO:19019871260.012
developmental process involved in reproductionGO:0003006660.012
Yeast
mapk cascadeGO:00001652880.012
organophosphate biosynthetic processGO:00904071630.012
gtp catabolic processGO:00061842370.012
cell cycle checkpointGO:00000751170.012
regulation of megakaryocyte differentiationGO:0045652220.012
hindbrain developmentGO:003090230.012
defense responseGO:00069523150.012
dna integrity checkpointGO:0031570710.012
response to lipidGO:00339932060.012
interspecies interaction between organismsGO:00444191560.012
cellular response to hormone stimulusGO:00328701250.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
head developmentGO:00603221080.012
cerebellum developmentGO:002154920.011
multi organism cellular processGO:00447641560.011
regulation of ion transportGO:00432691890.011
ossificationGO:00015031210.011
transmembrane transportGO:00550853990.011
regulation of ras protein signal transductionGO:00465781550.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
mitotic cell cycle checkpointGO:0007093680.011
hemopoiesisGO:00300971800.011
signal transduction in response to dna damageGO:0042770570.011
regulation of intracellular transportGO:00323861950.011
histone h4 acetylationGO:0043967470.011
regulation of dna metabolic processGO:00510521530.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
positive regulation of cell growthGO:0030307480.011
tube developmentGO:00352951250.011
negative regulation of apoptotic signaling pathwayGO:2001234970.011
regulation of protein transportGO:00512232130.011
organonitrogen compound biosynthetic processGO:19015662000.011
cellular response to organonitrogen compoundGO:00714171240.011
circulatory system developmentGO:00723592620.011
cellular response to radiationGO:0071478650.011
negative regulation of mitotic cell cycleGO:00459301020.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
wnt signaling pathwayGO:00160551560.011
protein localization to nucleusGO:00345041360.011
negative regulation of gene expression epigeneticGO:0045814190.011
Yeast
epithelial cell differentiationGO:00308551410.011
negative regulation of proteasomal protein catabolic processGO:1901799320.011
response to inorganic substanceGO:00100351270.011
protein importGO:00170381300.011
regulation of nucleotide catabolic processGO:00308112050.011
neuron developmentGO:00486661130.011
positive regulation of nucleoside metabolic processGO:00459791860.011
macromolecular complex disassemblyGO:0032984600.011
gtp metabolic processGO:00460392390.011
regulation of neural precursor cell proliferationGO:200017740.011
positive regulation of cell cycle processGO:00900681060.011
establishment of protein localization to membraneGO:00901501210.011
glycoprotein metabolic processGO:00091001100.011
primary neural tube formationGO:001402030.010
cellular ion homeostasisGO:00068731680.010
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010
regulation of response to external stimulusGO:00321012220.010
response to metal ionGO:0010038840.010
cellular response to oxidative stressGO:0034599850.010
positive regulation of cell cycleGO:00457871400.010
inorganic ion transmembrane transportGO:00986602310.010
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.010
regulation of reactive oxygen species metabolic processGO:2000377410.010
negative regulation of protein phosphorylationGO:00019331400.010
response to ionizing radiationGO:0010212650.010
negative regulation of kinase activityGO:00336731060.010
positive regulation of peptidase activityGO:0010952880.010
vasculature developmentGO:00019441810.010
mitotic sister chromatid separationGO:0051306180.010
chemotaxisGO:00069351570.010
sensory perception of painGO:001923340.010
divalent inorganic cation transportGO:00725111580.010
regulation of defense responseGO:00313471540.010
regulation of small gtpase mediated signal transductionGO:00510561560.010

HIST4H4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.024
disease of cellular proliferationDOID:145661740.019
immune system diseaseDOID:29141550.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.017
musculoskeletal system diseaseDOID:172230.017
central nervous system diseaseDOID:3311860.015
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.014
inherited metabolic disorderDOID:6552420.012
eye and adnexa diseaseDOID:14921500.011
connective tissue diseaseDOID:651090.011
eye diseaseDOID:56141490.010
neurodegenerative diseaseDOID:12891020.010