Homo sapiens

0 known processes

NALCN

sodium leak channel, non-selective

(Aliases: VGCNL1,CanIon,MGC74524,FLJ23913,bA430M15.1,FLJ44659,FLJ44764)

NALCN biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle contractionGO:0006936730.098
positive regulation of transportGO:00510503360.098
g protein coupled receptor signaling pathwayGO:00071862070.095
chemical homeostasisGO:00488783060.088
locomotory behaviorGO:000762610.079
ion homeostasisGO:00508012300.077
muscle system processGO:0003012810.075
system processGO:00030083490.073
cellular amino acid metabolic processGO:00065201160.071
regulation of ion transportGO:00432691890.071
regulation of muscle system processGO:0090257530.068
positive regulation of ion transportGO:0043270870.068
post embryonic developmentGO:000979120.066
transmembrane transportGO:00550853990.065
ion transmembrane transportGO:00342203380.063
amine metabolic processGO:0009308440.057
regulation of cellular amine metabolic processGO:0033238110.057
cellular amine metabolic processGO:0044106410.056
cation homeostasisGO:00550801890.056
cellular ketone metabolic processGO:0042180800.056
regulation of cellular amino acid metabolic processGO:000652160.053
blood circulationGO:00080151130.053
cardiac muscle cell contractionGO:008600340.053
cellular ion homeostasisGO:00068731680.052
cellular chemical homeostasisGO:00550821800.050
cellular cation homeostasisGO:00300031630.050
cellular homeostasisGO:00197251960.049
small gtpase mediated signal transductionGO:0007264780.046
cellular divalent inorganic cation homeostasisGO:00725031280.046
metal ion homeostasisGO:00550651690.046
organophosphate catabolic processGO:00464344300.046
regulation of muscle contractionGO:0006937450.046
regulation of cellular ketone metabolic processGO:0010565500.043
metal ion transportGO:00300012720.043
regulation of system processGO:00440571010.043
positive regulation of cellular amine metabolic processGO:003324070.042
cation transportGO:00068123310.042
actin filament based processGO:00300292240.042
positive regulation of cellular amino acid metabolic processGO:004576430.042
cellular metal ion homeostasisGO:00068751460.041
circulatory system processGO:00030131130.040
ras protein signal transductionGO:0007265730.040
female gamete generationGO:000729220.039
divalent inorganic cation homeostasisGO:00725071360.039
cation transmembrane transportGO:00986552380.038
purine ribonucleoside metabolic processGO:00461284370.038
inorganic ion transmembrane transportGO:00986602310.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
regulation of cellular component movementGO:00512703340.037
calcium ion homeostasisGO:00550741220.037
inorganic cation transmembrane transportGO:00986621940.037
multicellular organismal agingGO:001025930.037
purine ribonucleoside catabolic processGO:00461303980.037
nervous system developmentGO:00073992930.036
cytosolic calcium ion homeostasisGO:0051480890.036
nucleoside triphosphate metabolic processGO:00091414220.036
purine containing compound catabolic processGO:00725234110.036
lipid metabolic processGO:00066293810.035
purine nucleoside catabolic processGO:00061523980.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
purine nucleotide catabolic processGO:00061954050.035
ribonucleoside catabolic processGO:00424544060.035
purine ribonucleotide catabolic processGO:00091544040.035
oogenesisGO:004847720.035
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
nucleoside phosphate catabolic processGO:19012924120.034
determination of adult lifespanGO:000834020.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
glycosyl compound catabolic processGO:19016584130.033
ribonucleotide catabolic processGO:00092614050.033
neurological system processGO:00508771630.033
purine nucleoside triphosphate metabolic processGO:00091444120.032
nucleoside triphosphate catabolic processGO:00091433940.032
positive regulation of cellular component organizationGO:00511303760.032
negative regulation of catalytic activityGO:00430863350.032
vesicle mediated transportGO:00161923710.031
response to abiotic stimulusGO:00096283360.031
neuromuscular junction developmentGO:000752830.030
matingGO:000761810.030
cell morphogenesisGO:00009022960.030
memoryGO:000761330.030
cellular component morphogenesisGO:00329893140.029
monovalent inorganic cation transportGO:00156721280.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
positive regulation of hydrolase activityGO:00513453310.029
actin mediated cell contractionGO:0070252120.029
cell developmentGO:00484683280.029
regulation of transferase activityGO:00513383550.029
negative regulation of protein metabolic processGO:00512483910.029
response to biotic stimulusGO:00096072760.029
positive regulation of cytosolic calcium ion concentrationGO:0007204820.028
negative regulation of cellular component organizationGO:00511292350.028
positive regulation of phosphorylationGO:00423273940.028
membrane organizationGO:00610242920.028
negative regulation of cellular protein metabolic processGO:00322693530.028
cellular calcium ion homeostasisGO:00068741170.027
nucleotide catabolic processGO:00091664080.027
secretionGO:00469032540.027
response to other organismGO:00517072610.027
nucleoside catabolic processGO:00091644080.027
regulation of blood circulationGO:1903522590.026
regulation of cellular component biogenesisGO:00440872810.026
cell adhesionGO:00071553250.026
response to external biotic stimulusGO:00432072610.026
regulation of membrane potentialGO:0042391950.026
negative regulation of multicellular organismal processGO:00512413170.026
regulation of ion transmembrane transportGO:00347651320.026
single organism membrane organizationGO:00448022680.026
single organism cellular localizationGO:19025803320.026
positive regulation of protein phosphorylationGO:00019343130.026
adult locomotory behaviorGO:000834410.026
cell projection organizationGO:00300302520.026
positive regulation of cellular catabolic processGO:00313312840.025
negative regulation of phosphate metabolic processGO:00459362670.025
regenerationGO:003109940.025
segmentationGO:003528240.025
cellular lipid metabolic processGO:00442553030.025
regulation of cell migrationGO:00303342890.024
response to virusGO:00096151260.024
negative regulation of phosphorus metabolic processGO:00105632670.024
morphogenesis of embryonic epitheliumGO:001633140.024
rho protein signal transductionGO:0007266260.024
actin filament based movementGO:0030048170.024
regulation of synaptic plasticityGO:004816730.024
positive regulation of synaptic transmissionGO:005080640.024
regulation of purine nucleotide metabolic processGO:19005422640.024
protein catabolic processGO:00301633250.024
positive regulation of catabolic processGO:00098963100.024
immune responseGO:00069553070.024
positive regulation of developmental processGO:00510943140.024
response to oxygen containing compoundGO:19017003690.023
cardiac muscle contractionGO:0060048340.023
signal transduction by phosphorylationGO:00230142970.023
regulation of secretionGO:00510461940.023
mapk cascadeGO:00001652880.023
regulation of kinase activityGO:00435493140.023
guanosine containing compound metabolic processGO:19010682440.023
regulation of transmembrane transportGO:00347621390.023
cellular response to endogenous stimulusGO:00714953360.023
cellular macromolecule catabolic processGO:00442653800.023
striated muscle contractionGO:0006941520.023
guanosine containing compound catabolic processGO:19010692390.023
regulation of mapk cascadeGO:00434082620.022
regulation of nucleotide metabolic processGO:00061402690.022
regulation of protein kinase activityGO:00458592890.022
cytoplasmic transportGO:00164823790.022
gtp catabolic processGO:00061842370.022
cellular macromolecular complex assemblyGO:00346223240.022
negative regulation of hydrolase activityGO:00513461820.022
regulation of purine nucleotide catabolic processGO:00331212050.022
neurogenesisGO:00220081690.022
regulation of cell cycleGO:00517263930.021
carbohydrate derivative biosynthetic processGO:19011372070.021
negative regulation of cell deathGO:00605483450.021
mitotic cell cycleGO:00002783260.021
regulation of nucleoside metabolic processGO:00091182090.021
startle responseGO:000196430.021
small molecule biosynthetic processGO:00442831570.021
protein maturationGO:00516042330.021
gtp metabolic processGO:00460392390.021
oocyte developmentGO:004859910.021
dephosphorylationGO:00163112090.021
cellular response to dna damage stimulusGO:00069743790.021
regulation of cell differentiationGO:00455953930.020
cellular response to oxygen containing compoundGO:19017012760.020
defense responseGO:00069523150.020
regulation of proteolysisGO:00301622930.020
regulation of protein localizationGO:00328802960.020
innate immune responseGO:00450871780.020
oocyte differentiationGO:000999420.020
biological adhesionGO:00226103310.020
regulation of cell motilityGO:20001452990.020
carbohydrate metabolic processGO:00059752070.020
regulation of actin filament based processGO:00329701410.020
anion transportGO:00068201610.020
negative regulation of transportGO:00510511760.020
neurotransmitter secretionGO:000726940.020
single organism carbohydrate metabolic processGO:00447231930.020
lipid biosynthetic processGO:00086101770.020
regulation of cellular response to stressGO:00801352440.020
regulation of establishment of protein localizationGO:00702012420.020
regulation of response to external stimulusGO:00321012220.020
positive regulation of nucleotide catabolic processGO:00308131850.019
positive regulation of nucleoside metabolic processGO:00459791860.019
protein processingGO:00164852260.019
positive regulation of transferase activityGO:00513472270.019
blastoderm segmentationGO:000735020.019
positive regulation of kinase activityGO:00336742040.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
regulation of anatomical structure morphogenesisGO:00226032860.019
action potentialGO:0001508340.019
positive regulation of nucleotide metabolic processGO:00459812300.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of locomotionGO:00400123290.019
positive regulation of protein kinase activityGO:00458601900.019
anterior posterior axis specificationGO:000994820.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
response to organic cyclic compoundGO:00140702040.019
secretion by cellGO:00329402260.019
protein o linked glycosylation via serineGO:001824230.019
peripheral nervous system developmentGO:000742220.019
spermatid differentiationGO:004851540.019
regulation of gtp catabolic processGO:00331241800.018
mitotic cell cycle processGO:19030472860.018
protein localization to organelleGO:00333652800.018
positive regulation of immune system processGO:00026842830.018
cellular protein catabolic processGO:00442572610.018
negative regulation of cellular amine metabolic processGO:003323930.018
growthGO:00400072020.018
positive regulation of gtp catabolic processGO:00331261660.018
generation of neuronsGO:00486991520.018
nitrogen compound transportGO:00717051910.018
positive regulation of cell deathGO:00109422630.018
associative learningGO:000830610.018
rhythmic behaviorGO:000762220.018
cytokine productionGO:00018162470.018
intracellular protein transportGO:00068862700.018
negative regulation of apoptotic processGO:00430663160.018
neuroblast proliferationGO:000740540.018
negative regulation of programmed cell deathGO:00430693210.018
protein oligomerizationGO:00512591730.018
regulation of cytokine productionGO:00018172320.017
regulation of metal ion transportGO:00109591200.017
sensory perception of painGO:001923340.017
organonitrogen compound biosynthetic processGO:19015662000.017
positive regulation of gtpase activityGO:00435471660.017
neuron differentiationGO:00301821380.017
limbic system developmentGO:002176130.017
regulation of nucleotide catabolic processGO:00308112050.017
positive regulation of locomotionGO:00400171860.017
monocarboxylic acid metabolic processGO:00327871850.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
regulation of cell cycle processGO:00105642660.017
positive regulation of cell proliferationGO:00082843010.017
microtubule based processGO:00070172100.017
multicellular organismal signalingGO:0035637340.017
calcium ion transportGO:00068161470.017
regulation of protein serine threonine kinase activityGO:00719001790.017
regulation of secretion by cellGO:19035301770.017
negative regulation of protein modification processGO:00314002000.017
endomembrane system organizationGO:00102561960.017
spermatid developmentGO:000728640.017
hindbrain developmentGO:003090230.017
maintenance of locationGO:00512351120.017
regulation of cell developmentGO:00602841610.017
embryonic epithelial tube formationGO:000183840.017
protein modification by small protein conjugationGO:00324463420.017
taxisGO:00423301570.017
regulation of anatomical structure sizeGO:00900661010.016
cell growthGO:00160491600.016
potassium ion transmembrane transportGO:0071805600.016
motor neuron axon guidanceGO:000804520.016
circulatory system developmentGO:00723592620.016
potassium ion transportGO:0006813620.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
tripartite regional subdivisionGO:000735120.016
negative regulation of intracellular signal transductionGO:19025321830.016
compound eye developmentGO:004874910.016
behaviorGO:00076101120.016
regulation of intracellular transportGO:00323861950.016
nerve developmentGO:002167540.016
cellular protein complex assemblyGO:00436231880.016
regulation of gtpase activityGO:00430871800.016
positive regulation of apoptotic processGO:00430652460.016
anterior posterior axis specification embryoGO:000859520.015
regulation of neurotransmitter secretionGO:004692830.015
sleepGO:003043120.015
protein ubiquitinationGO:00165673140.015
protein o linked glycosylation via threonineGO:001824340.015
neuron developmentGO:00486661130.015
nucleoside monophosphate metabolic processGO:00091231910.015
cellular response to growth factor stimulusGO:00713631970.015
regulation of protein transportGO:00512232130.015
negative regulation of developmental processGO:00510932470.015
divalent inorganic cation transportGO:00725111580.015
regulation of cytoskeleton organizationGO:00514931770.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
positive regulation of mapk cascadeGO:00434101900.015
divalent metal ion transportGO:00708381520.015
regulation of vesicle mediated transportGO:00606271300.015
response to growth factorGO:00708482050.015
organophosphate biosynthetic processGO:00904071630.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of growthGO:00400081650.015
organ formationGO:004864530.015
oxidation reduction processGO:00551143960.015
response to nitrogen compoundGO:19016981840.015
microtubule cytoskeleton organizationGO:00002261760.015
actin cytoskeleton organizationGO:00300362070.015
positive regulation of cell differentiationGO:00455972110.015
circadian behaviorGO:004851220.015
positive regulation of secretionGO:00510471160.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
regulation of ras protein signal transductionGO:00465781550.015
central nervous system developmentGO:00074171230.015
transmission of nerve impulseGO:0019226110.014
apoptotic signaling pathwayGO:00971902680.014
negative regulation of cell proliferationGO:00082852280.014
glycoprotein metabolic processGO:00091001100.014
positive regulation of programmed cell deathGO:00430682490.014
membrane hyperpolarizationGO:006008110.014
photoreceptor cell differentiationGO:004653020.014
visual learningGO:000854210.014
cardiovascular system developmentGO:00723582620.014
protein localization to membraneGO:00726571600.014
organic acid biosynthetic processGO:0016053970.014
metencephalon developmentGO:002203720.014
reactive nitrogen species metabolic processGO:200105730.014
regulation of cell morphogenesisGO:00226041530.014
regulation of cell projection organizationGO:00313441070.014
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.014
negative regulation of phosphorylationGO:00423261740.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
multicellular organismal response to stressGO:003355510.014
response to hormoneGO:00097251750.014
positive regulation of cellular component movementGO:00512721810.014
response to cytokineGO:00340972320.014
visual behaviorGO:000763220.014
cell fate determinationGO:000170930.014
regulation of protein maturationGO:19033171500.014
chemotaxisGO:00069351570.014
angiogenesisGO:00015251470.014
positive regulation of organelle organizationGO:00106381950.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
protein targetingGO:00066051870.014
cell morphogenesis involved in differentiationGO:00009041440.014
epithelium developmentGO:00604292270.014
cellular potassium ion transportGO:0071804600.014
regulation of protein processingGO:00706131500.014
regulation of meiotic cell cycleGO:005144540.014
sensory perceptionGO:00076001030.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
posttranscriptional regulation of gene expressionGO:00106082130.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
response to lipidGO:00339932060.013
stem cell divisionGO:001714520.013
cell cell signalingGO:00072671550.013
regulation of protein catabolic processGO:00421761550.013
cell part morphogenesisGO:00329901370.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
ameboidal type cell migrationGO:00016671350.013
atp metabolic processGO:00460341760.013
response to axon injuryGO:004867810.013
negative regulation of cell cycleGO:00457861930.013
glycerolipid metabolic processGO:00464861070.013
proteasomal protein catabolic processGO:00104981760.013
modification dependent macromolecule catabolic processGO:00436322120.013
organelle assemblyGO:00709251760.013
reproductive processGO:00224141060.013
regulation of peptidase activityGO:00525471800.013
regulation of cytoplasmic transportGO:19036491490.013
regulation of multi organism processGO:00439001570.013
regulation of endopeptidase activityGO:00525481700.013
regulation of transporter activityGO:0032409820.013
negative regulation of protein processingGO:00109551420.013
chromatin organizationGO:00063253510.013
regulation of protein complex assemblyGO:00432541470.013
positive regulation of cellular component biogenesisGO:00440891580.013
sequestering of metal ionGO:0051238240.013
wnt signaling pathwayGO:00160551560.013
cell projection morphogenesisGO:00488581290.013
establishment of protein localization to organelleGO:00725941720.013
chromatin modificationGO:00165682980.013
response to radiationGO:00093141510.013
cell divisionGO:00513011680.013
cell cycle phase transitionGO:00447701730.013
response to organonitrogen compoundGO:00102431560.013
response to fungusGO:000962040.013
regulation of mitotic cell cycleGO:00073461890.013
modification dependent protein catabolic processGO:00199412090.013
positive regulation of secretion by cellGO:19035321080.013
regulation of ras gtpase activityGO:00323181280.013
peptidyl tyrosine modificationGO:00182121700.013
cellular response to nitrogen compoundGO:19016991440.013
positive regulation of ras gtpase activityGO:00323201170.013
inner ear morphogenesisGO:004247240.013
regulation of immune responseGO:00507762010.013
cellular response to cytokine stimulusGO:00713451810.013
protein autophosphorylationGO:00467771230.013
ubiquitin dependent protein catabolic processGO:00065112060.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
rna processingGO:00063962550.013
neuron projection developmentGO:00311751060.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of homeostatic processGO:00328441210.012
histone modificationGO:00165702510.012
tissue regenerationGO:004224630.012
negative regulation of organelle organizationGO:00106391260.012
sodium ion transportGO:0006814610.012
thymus developmentGO:004853830.012
carboxylic acid biosynthetic processGO:0046394970.012
dna repairGO:00062811980.012
regulation of cell adhesionGO:00301551660.012
reactive oxygen species metabolic processGO:0072593750.012
sodium ion transmembrane transportGO:0035725590.012
mitotic cell cycle phase transitionGO:00447721620.012
regulation of dna metabolic processGO:00510521530.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
glial cell migrationGO:000834740.012
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathwayGO:005148260.012
negative regulation of protein maturationGO:19033181420.012
cell activationGO:00017752130.012
peptidyl tyrosine phosphorylationGO:00181081700.012
regulation of neural precursor cell proliferationGO:200017740.012
multi organism cellular processGO:00447641560.012
covalent chromatin modificationGO:00165692540.012
nuclear transportGO:00511691790.012
regulation of dephosphorylationGO:0035303960.012
tissue migrationGO:00901301190.012
neural tube formationGO:000184130.012
phospholipid metabolic processGO:0006644990.012
positive regulation of cell migrationGO:00303351720.012
nucleocytoplasmic transportGO:00069131760.012
tube closureGO:006060630.012
interspecies interaction between organismsGO:00444191560.012
negative regulation of proteolysisGO:00458611320.012
fatty acid metabolic processGO:00066311150.012
lung alveolus developmentGO:004828640.012
positive regulation of cytokine productionGO:00018191670.012
primary neural tube formationGO:001402030.012
negative regulation of synaptic transmissionGO:005080520.012
sequestering of calcium ionGO:0051208170.012
organic hydroxy compound metabolic processGO:19016151470.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of cell growthGO:00015581350.011
positive regulation of immune responseGO:00507781590.011
morphogenesis of a polarized epitheliumGO:000173830.011
leukocyte activationGO:00453211640.011
single organism cell adhesionGO:00986021790.011
glycoprotein biosynthetic processGO:0009101910.011
positive regulation of cell motilityGO:20001471770.011
atp catabolic processGO:00062001570.011
nucleoside monophosphate catabolic processGO:00091251590.011
establishment of protein localization to membraneGO:00901501210.011
peptidyl serine modificationGO:00182091060.011
behavioral response to ethanolGO:004814920.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
meiotic chromosome segregationGO:004513240.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
regulation of excitatory postsynaptic membrane potentialGO:006007910.011
negative regulation of transferase activityGO:00513481240.011
endocytosisGO:00068971590.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
cell projection assemblyGO:00300311260.011
epithelial cell migrationGO:00106311190.011
head developmentGO:00603221080.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
response to woundingGO:00096111680.011
mitochondrion organizationGO:00070051560.011
sulfur compound metabolic processGO:00067901010.011
alcohol metabolic processGO:00060661140.011
positive regulation of protein transportGO:00512221350.011
neural tube closureGO:000184330.011
viral processGO:00160321460.011
regulation of defense responseGO:00313471540.011
forebrain generation of neuronsGO:002187230.011
long term memoryGO:000761620.011
synaptic transmission cholinergicGO:000727120.011
regulation of postsynaptic membrane potentialGO:006007810.011
response to inorganic substanceGO:00100351270.011
glycerophospholipid metabolic processGO:0006650840.011
meiosis iGO:000712740.011
activation of protein kinase activityGO:0032147900.011
protein localization to nucleusGO:00345041360.011
heart contractionGO:0060047620.011
regulation of apoptotic signaling pathwayGO:20012331750.011
heart processGO:0003015620.011
organ morphogenesisGO:00098871470.011
axis elongationGO:000340140.011
neural crest cell developmentGO:001403230.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
organelle fissionGO:00482851490.010

NALCN disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.033
central nervous system diseaseDOID:3311860.033
disease of metabolismDOID:00146672950.026
musculoskeletal system diseaseDOID:172230.025
sensory system diseaseDOID:00501552030.021
inherited metabolic disorderDOID:6552420.019
brain diseaseDOID:936730.016
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.016
cardiovascular system diseaseDOID:12871060.016
organ system cancerDOID:00506861640.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.013
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.012
neurodegenerative diseaseDOID:12891020.012
disease of mental healthDOID:150700.011
retinal diseaseDOID:56791180.010