Homo sapiens

29 known processes

UBR4

ubiquitin protein ligase E3 component n-recognin 4

(Aliases: KIAA1307,FLJ41863,p600,ZUBR1,RBAF600,KIAA0462)

UBR4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein ubiquitinationGO:00165673140.155
cellular macromolecule catabolic processGO:00442653800.130
cellular protein catabolic processGO:00442572610.115
modification dependent macromolecule catabolic processGO:00436322120.112
protein processingGO:00164852260.106
proteasomal protein catabolic processGO:00104981760.097
protein catabolic processGO:00301633250.097
regulation of protein catabolic processGO:00421761550.079
protein maturationGO:00516042330.078
post embryonic developmentGO:000979120.072
negative regulation of cellular protein metabolic processGO:00322693530.070
Human
protein modification by small protein conjugationGO:00324463420.067
small gtpase mediated signal transductionGO:0007264780.066
negative regulation of protein metabolic processGO:00512483910.065
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.061
regulation of proteasomal protein catabolic processGO:0061136870.060
modification dependent protein catabolic processGO:00199412090.057
multicellular organismal agingGO:001025930.057
ras protein signal transductionGO:0007265730.057
proteolysis involved in cellular protein catabolic processGO:00516032440.055
i kappab kinase nf kappab signalingGO:00072491660.055
positive regulation of cellular component organizationGO:00511303760.055
regulation of protein modification by small protein conjugation or removalGO:19033201070.052
Human
regulation of cellular amino acid metabolic processGO:000652160.052
cellular amino acid metabolic processGO:00065201160.052
regulation of proteolysisGO:00301622930.050
regulation of protein maturationGO:19033171500.050
maintenance of location in cellGO:0051651620.048
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.048
secretion by cellGO:00329402260.046
determination of adult lifespanGO:000834020.045
regulation of i kappab kinase nf kappab signalingGO:00431221620.044
amine metabolic processGO:0009308440.044
negative regulation of protein processingGO:00109551420.044
purine nucleoside triphosphate metabolic processGO:00091444120.043
negative regulation of transportGO:00510511760.043
negative regulation of protein maturationGO:19033181420.042
regulation of cytokine productionGO:00018172320.042
cellular component morphogenesisGO:00329893140.042
mitotic cell cycleGO:00002783260.040
organophosphate catabolic processGO:00464344300.040
regulation of cellular protein catabolic processGO:1903362960.040
regulation of cell cycleGO:00517263930.039
purine ribonucleoside metabolic processGO:00461284370.039
regulation of protein ubiquitinationGO:0031396950.039
Human
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.037
secretionGO:00469032540.037
cytokine productionGO:00018162470.037
negative regulation of catabolic processGO:00098951040.035
bone mineralizationGO:0030282340.035
maintenance of protein locationGO:0045185570.035
ribonucleoside triphosphate metabolic processGO:00091994120.035
cellular response to dna damage stimulusGO:00069743790.035
Human
cell morphogenesisGO:00009022960.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
regulation of protein processingGO:00706131500.034
vesicle mediated transportGO:00161923710.034
cellular amine metabolic processGO:0044106410.034
ubiquitin dependent protein catabolic processGO:00065112060.033
regulation of cellular amine metabolic processGO:0033238110.033
ribonucleoside catabolic processGO:00424544060.033
endomembrane system organizationGO:00102561960.033
positive regulation of cellular catabolic processGO:00313312840.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
compound eye developmentGO:004874910.032
negative regulation of cell deathGO:00605483450.032
mitotic cell cycle processGO:19030472860.032
purine nucleotide catabolic processGO:00061954050.032
protein modification by small protein removalGO:0070646920.031
rho protein signal transductionGO:0007266260.031
response to nitrogen compoundGO:19016981840.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
cellular ketone metabolic processGO:0042180800.031
nucleotide catabolic processGO:00091664080.031
nitrogen compound transportGO:00717051910.031
purine containing compound catabolic processGO:00725234110.030
cellular macromolecular complex assemblyGO:00346223240.029
regulation of transferase activityGO:00513383550.029
regulation of anatomical structure morphogenesisGO:00226032860.028
ossificationGO:00015031210.028
nucleoside triphosphate metabolic processGO:00091414220.027
negative regulation of catalytic activityGO:00430863350.027
female gamete generationGO:000729220.027
positive regulation of catabolic processGO:00098963100.027
nucleoside phosphate catabolic processGO:19012924120.027
regulation of bone mineralizationGO:0030500290.026
regulation of establishment of protein localizationGO:00702012420.026
Human
regulation of protein complex assemblyGO:00432541470.026
regulation of cellular ketone metabolic processGO:0010565500.026
oxidation reduction processGO:00551143960.026
biomineral tissue developmentGO:0031214390.025
glycosyl compound catabolic processGO:19016584130.025
nervous system developmentGO:00073992930.025
Fly
organic hydroxy compound metabolic processGO:19016151470.025
positive regulation of phosphorylationGO:00423273940.025
regulation of cell morphogenesisGO:00226041530.025
regulation of purine nucleotide metabolic processGO:19005422640.025
chromatin modificationGO:00165682980.025
Human
cellular response to oxygen containing compoundGO:19017012760.025
protein targetingGO:00066051870.025
Human
mitotic cell cycle phase transitionGO:00447721620.024
regulation of biomineral tissue developmentGO:0070167310.024
regulation of ras protein signal transductionGO:00465781550.024
locomotory behaviorGO:000762610.024
negative regulation of cellular catabolic processGO:0031330830.024
segmentationGO:003528240.024
ribonucleotide catabolic processGO:00092614050.024
negative regulation of hydrolase activityGO:00513461820.024
establishment of protein localization to organelleGO:00725941720.024
Human
response to biotic stimulusGO:00096072760.023
purine ribonucleoside catabolic processGO:00461303980.023
gtp metabolic processGO:00460392390.023
carbohydrate derivative biosynthetic processGO:19011372070.023
cell projection organizationGO:00300302520.023
regulation of intracellular transportGO:00323861950.023
Human
extrinsic apoptotic signaling pathwayGO:00971911190.023
ion transmembrane transportGO:00342203380.023
regulation of small gtpase mediated signal transductionGO:00510561560.023
positive regulation of gtp catabolic processGO:00331261660.023
regulation of ossificationGO:0030278580.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
cell adhesionGO:00071553250.022
negative regulation of programmed cell deathGO:00430693210.022
membrane organizationGO:00610242920.022
regulation of secretionGO:00510461940.022
anterior posterior axis specificationGO:000994820.022
memoryGO:000761330.022
guanosine containing compound metabolic processGO:19010682440.021
negative regulation of intracellular signal transductionGO:19025321830.021
inorganic ion transmembrane transportGO:00986602310.021
regulation of transmembrane transporter activityGO:0022898740.021
response to external biotic stimulusGO:00432072610.021
regulation of secretion by cellGO:19035301770.021
negative regulation of protein transportGO:0051224750.021
regulation of cellular component biogenesisGO:00440872810.021
protein autophosphorylationGO:00467771230.021
regenerationGO:003109940.021
positive regulation of cellular amine metabolic processGO:003324070.021
protein polyubiquitinationGO:00002091100.020
Human
cell projection assemblyGO:00300311260.020
maintenance of locationGO:00512351120.020
chemical homeostasisGO:00488783060.020
negative regulation of cellular component organizationGO:00511292350.020
Human
response to cytokineGO:00340972320.020
regulation of cell cycle processGO:00105642660.020
actin filament based processGO:00300292240.020
regulation of transporter activityGO:0032409820.020
oogenesisGO:004847720.020
meiosis iGO:000712740.020
negative regulation of phosphorus metabolic processGO:00105632670.020
actin mediated cell contractionGO:0070252120.020
immune responseGO:00069553070.020
cellular response to growth factor stimulusGO:00713631970.020
cation transportGO:00068123310.020
single organism cell adhesionGO:00986021790.020
neurogenesisGO:00220081690.019
Fly
melanin metabolic processGO:000658210.019
protein localization to organelleGO:00333652800.019
Human
single organism cellular localizationGO:19025803320.019
Human
response to growth factorGO:00708482050.019
negative regulation of cellular amine metabolic processGO:003323930.019
blastoderm segmentationGO:000735020.019
intracellular protein transportGO:00068862700.019
Human
cation transmembrane transportGO:00986552380.019
response to organonitrogen compoundGO:00102431560.019
dephosphorylationGO:00163112090.019
ion homeostasisGO:00508012300.019
neuromuscular junction developmentGO:000752830.019
protein importGO:00170381300.019
Human
transmembrane transportGO:00550853990.019
response to organic cyclic compoundGO:00140702040.019
protein secretionGO:0009306980.019
cellular response to nitrogen compoundGO:19016991440.019
innate immune responseGO:00450871780.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
regulation of cytoskeleton organizationGO:00514931770.018
negative regulation of protein catabolic processGO:0042177590.018
negative regulation of proteolysisGO:00458611320.018
spermatid differentiationGO:004851540.018
Fly
positive regulation of developmental processGO:00510943140.018
vesicle organizationGO:0016050620.018
microtubule cytoskeleton organizationGO:00002261760.018
negative regulation of phosphate metabolic processGO:00459362670.018
positive regulation of apoptotic processGO:00430652460.018
system processGO:00030083490.018
purine ribonucleotide catabolic processGO:00091544040.018
cellular response to histamineGO:007142030.018
regulation of kinase activityGO:00435493140.018
negative regulation of developmental processGO:00510932470.018
cell cycle phase transitionGO:00447701730.018
cytoplasmic transportGO:00164823790.018
Human
nucleoside triphosphate catabolic processGO:00091433940.018
mapk cascadeGO:00001652880.018
organelle assemblyGO:00709251760.017
regulation of cell differentiationGO:00455953930.017
organelle fissionGO:00482851490.017
negative regulation of proteasomal protein catabolic processGO:1901799320.017
regulation of nucleoside metabolic processGO:00091182090.017
covalent chromatin modificationGO:00165692540.017
Human
lipid metabolic processGO:00066293810.017
sequestering of metal ionGO:0051238240.017
single organism membrane organizationGO:00448022680.017
purine nucleoside catabolic processGO:00061523980.017
anterior posterior axis specification embryoGO:000859520.017
regulation of nucleotide metabolic processGO:00061402690.017
gtp catabolic processGO:00061842370.017
cellular homeostasisGO:00197251960.017
regulation of protein localization to nucleusGO:1900180850.017
Human
cellular lipid metabolic processGO:00442553030.017
negative regulation of cytokine productionGO:0001818820.017
neurological system processGO:00508771630.017
spermatid developmentGO:000728640.017
Fly
negative regulation of protein modification processGO:00314002000.016
Human
cell cycle checkpointGO:00000751170.016
ribonucleoside triphosphate catabolic processGO:00092033910.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
positive regulation of nucleoside metabolic processGO:00459791860.016
actin filament based movementGO:0030048170.016
regulation of nucleotide catabolic processGO:00308112050.016
microtubule based processGO:00070172100.016
actin cytoskeleton organizationGO:00300362070.016
chromatin organizationGO:00063253510.016
Human
oocyte developmentGO:004859910.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of immune responseGO:00507762010.016
metal ion homeostasisGO:00550651690.016
positive regulation of cell proliferationGO:00082843010.016
nuclear importGO:00511701060.016
Human
positive regulation of cell differentiationGO:00455972110.016
regulation of meiotic cell cycleGO:005144540.016
divalent inorganic cation transportGO:00725111580.016
protein deubiquitinationGO:0016579790.016
single organismal cell cell adhesionGO:00163371480.016
negative regulation of cellular protein catabolic processGO:1903363380.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
peripheral nervous system developmentGO:000742220.016
regulation of ion transportGO:00432691890.016
regulation of response to external stimulusGO:00321012220.016
positive regulation of purine nucleotide catabolic processGO:00331231850.015
calcium ion transportGO:00068161470.015
positive regulation of cellular component biogenesisGO:00440891580.015
cellular response to organic cyclic compoundGO:00714071270.015
nucleocytoplasmic transportGO:00069131760.015
Human
single organism nuclear importGO:19025931040.015
Human
cellular protein complex assemblyGO:00436231880.015
rna processingGO:00063962550.015
rna interferenceGO:001624640.015
apoptotic signaling pathwayGO:00971902680.015
positive regulation of organelle organizationGO:00106381950.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
atp metabolic processGO:00460341760.015
regulation of wnt signaling pathwayGO:00301111230.015
Human
regulation of protein kinase activityGO:00458592890.015
regulation of nucleocytoplasmic transportGO:0046822980.015
Human
regulation of mitotic cell cycle phase transitionGO:19019901180.015
cell developmentGO:00484683280.015
Fly
positive regulation of transportGO:00510503360.015
Human
regulation of cell cycle phase transitionGO:19019871260.015
histone modificationGO:00165702510.015
Human
secretory granule organizationGO:003336320.015
regulation of cell adhesionGO:00301551660.015
regulation of protein import into nucleusGO:0042306780.015
Human
metal ion transportGO:00300012720.015
motor neuron axon guidanceGO:000804520.015
cell part morphogenesisGO:00329901370.015
positive regulation of nucleotide metabolic processGO:00459812300.015
positive regulation of gtpase activityGO:00435471660.014
regulation of protein targetingGO:1903533910.014
Human
purine nucleoside monophosphate metabolic processGO:00091261860.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
photoreceptor cell differentiationGO:004653020.014
cellular response to organonitrogen compoundGO:00714171240.014
cellular cation homeostasisGO:00300031630.014
regulation of ion transmembrane transporter activityGO:0032412720.014
cellular chemical homeostasisGO:00550821800.014
neuroblast proliferationGO:000740540.014
associative learningGO:000830610.014
sequestering of calcium ionGO:0051208170.014
regulation of mitotic cell cycleGO:00073461890.014
regulation of gtpase activityGO:00430871800.014
cell divisionGO:00513011680.014
nucleoside catabolic processGO:00091644080.014
cellular response to endogenous stimulusGO:00714953360.014
glial cell migrationGO:000834740.014
guanosine containing compound catabolic processGO:19010692390.014
defense responseGO:00069523150.014
cell projection morphogenesisGO:00488581290.014
cation homeostasisGO:00550801890.014
nuclear divisionGO:00002801280.014
negative regulation of cell proliferationGO:00082852280.014
growthGO:00400072020.014
Fly
matingGO:000761810.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
negative regulation of multicellular organismal processGO:00512413170.014
cellular ion homeostasisGO:00068731680.014
amide transportGO:0042886760.014
positive regulation of defense responseGO:0031349870.014
regulation of cellular response to stressGO:00801352440.014
Human
regulation of cellular component movementGO:00512703340.013
posttranscriptional regulation of gene expressionGO:00106082130.013
nuclear transportGO:00511691790.013
Human
regulation of protein serine threonine kinase activityGO:00719001790.013
limbic system developmentGO:002176130.013
cytokine secretionGO:0050663640.013
cell morphogenesis involved in differentiationGO:00009041440.013
cell growthGO:00160491600.013
Fly
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.013
Human
regulation of bindingGO:00510981110.013
regulation of protein polymerizationGO:0032271630.013
taxisGO:00423301570.013
chromosome segregationGO:00070591140.013
regulation of synaptic plasticityGO:004816730.013
protein localization to membraneGO:00726571600.013
tripartite regional subdivisionGO:000735120.013
embryonic camera type eye morphogenesisGO:004859620.013
positive regulation of hydrolase activityGO:00513453310.013
embryonic camera type eye developmentGO:003107620.013
positive regulation of nucleotide catabolic processGO:00308131850.013
negative regulation of apoptotic processGO:00430663160.013
response to abiotic stimulusGO:00096283360.013
immune effector processGO:00022521590.013
regulation of protein secretionGO:0050708860.013
positive regulation of synaptic transmissionGO:005080640.013
cellular response to cytokine stimulusGO:00713451810.013
morphogenesis of embryonic epitheliumGO:001633140.013
metencephalon developmentGO:002203720.013
positive regulation of protein complex assemblyGO:0031334860.013
regulation of phosphatase activityGO:0010921810.013
cellular response to ammonium ionGO:007124240.013
wound healingGO:00420601150.013
regulation of cell morphogenesis involved in differentiationGO:0010769830.013
syncytium formation by plasma membrane fusionGO:000076820.013
regulation of gtp catabolic processGO:00331241800.013
inorganic cation transmembrane transportGO:00986621940.013
anion transportGO:00068201610.012
positive regulation of cell cycle processGO:00900681060.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
positive regulation of mapk cascadeGO:00434101900.012
neurotransmitter secretionGO:000726940.012
regulation of cytokine secretionGO:0050707570.012
oocyte differentiationGO:000999420.012
embryonic placenta developmentGO:000189210.012
response to metal ionGO:0010038840.012
response to decreased oxygen levelsGO:0036293960.012
methylationGO:00322591060.012
regulation of mapk cascadeGO:00434082620.012
regulation of meiosisGO:004002030.012
single organism reproductive processGO:0044702980.012
Fly
glycoprotein biosynthetic processGO:0009101910.012
stem cell divisionGO:001714520.012
tissue regenerationGO:004224630.012
nucleoside monophosphate metabolic processGO:00091231910.012
generation of neuronsGO:00486991520.012
organophosphate biosynthetic processGO:00904071630.012
regulation of protein localizationGO:00328802960.012
Human
regulation of response to woundingGO:19030341010.012
blastocyst developmentGO:000182430.012
protein acylationGO:00435431380.012
cell type specific apoptotic processGO:00972851250.012
cellular metal ion homeostasisGO:00068751460.012
response to hypoxiaGO:0001666960.012
signal transduction by phosphorylationGO:00230142970.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
regulation of leukocyte activationGO:00026941150.012
negative regulation of phosphorylationGO:00423261740.012
single organism carbohydrate metabolic processGO:00447231930.012
biological adhesionGO:00226103310.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
visual behaviorGO:000763220.012
protein import into nucleusGO:00066061040.012
Human
cerebellum developmentGO:002154920.012
response to woundingGO:00096111680.012
regulation of defense responseGO:00313471540.012
nucleobase containing compound transportGO:0015931510.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.012
regulation of cell growthGO:00015581350.012
lipid biosynthetic processGO:00086101770.012
negative regulation of secretionGO:0051048580.011
peptidyl lysine modificationGO:00182051440.011
dna repairGO:00062811980.011
Human
cell substrate adhesionGO:00315891320.011
positive regulation of cellular component movementGO:00512721810.011
ribonucleoprotein complex biogenesisGO:00226131160.011
establishment of nucleus localizationGO:004002310.011
lung alveolus developmentGO:004828640.011
regulation of ion transmembrane transportGO:00347651320.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
response to radiationGO:00093141510.011
detection of chemical stimulusGO:0009593550.011
negative regulation of transferase activityGO:00513481240.011
embryonic eye morphogenesisGO:004804820.011
regulation of neural precursor cell proliferationGO:200017740.011
adult locomotory behaviorGO:000834410.011
regulation of apoptotic signaling pathwayGO:20012331750.011
regulation of leukocyte differentiationGO:1902105610.011
lymphocyte activationGO:00466491330.011
regulation of cell projection organizationGO:00313441070.011
regulation of growthGO:00400081650.011
regulation of intracellular protein transportGO:00331571230.011
Human
carbohydrate metabolic processGO:00059752070.011
regulation of nuclear divisionGO:0051783650.011
regulation of ras gtpase activityGO:00323181280.011
negative regulation of cell cycleGO:00457861930.011
hindbrain developmentGO:003090230.011
positive regulation of immune system processGO:00026842830.011
organ formationGO:004864530.011
inner ear morphogenesisGO:004247240.011
protein acetylationGO:00064731160.011
regulation of dephosphorylationGO:0035303960.011
protein oligomerizationGO:00512591730.011
regulation of microtubule based processGO:0032886740.011
intracellular receptor signaling pathwayGO:00305221040.011
Human
regulation of actin filament based processGO:00329701410.011
ameboidal type cell migrationGO:00016671350.011
regulation of axon guidanceGO:190266730.011
positive regulation of cell activationGO:0050867810.011
lens development in camera type eyeGO:000208820.011
cellular amide metabolic processGO:0043603690.011
internal peptidyl lysine acetylationGO:0018393970.011
cardiovascular system developmentGO:00723582620.011
protein targeting to nucleusGO:00447441040.011
Human
positive regulation of cell deathGO:00109422630.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
somitogenesisGO:000175620.011
cardiac muscle cell contractionGO:008600340.011
cell fate determinationGO:000170930.011
calcium ion transmembrane transportGO:0070588760.011
calcium ion homeostasisGO:00550741220.011
rna splicingGO:00083801310.011
embryonic epithelial tube formationGO:000183840.010
divalent inorganic cation homeostasisGO:00725071360.010
epithelial cell migrationGO:00106311190.010
nucleus localizationGO:005164710.010
glycoprotein metabolic processGO:00091001100.010
cellular response to muramyl dipeptideGO:007122530.010
peptide transportGO:0015833740.010
negative regulation of kinase activityGO:00336731060.010
mitochondrion organizationGO:00070051560.010
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435300.010
dna conformation changeGO:00711031130.010
regulation of locomotionGO:00400123290.010
negative regulation of peptidase activityGO:0010466910.010
response to axon injuryGO:004867810.010
actin polymerization or depolymerizationGO:0008154560.010
erk1 and erk2 cascadeGO:00703711040.010
epithelial cell differentiationGO:00308551410.010
negative regulation of organelle organizationGO:00106391260.010
Human
neuron developmentGO:00486661130.010
protein polymerizationGO:0051258710.010
mitotic nuclear divisionGO:00070671190.010
positive regulation of cell cycleGO:00457871400.010
convergent extensionGO:006002610.010
nerve developmentGO:002167540.010
regulation of transmembrane transportGO:00347621390.010
positive regulation of cytoskeleton organizationGO:0051495830.010

UBR4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.032
sensory system diseaseDOID:00501552030.032
musculoskeletal system diseaseDOID:172230.029
disease of metabolismDOID:00146672950.023
central nervous system diseaseDOID:3311860.023
disease of cellular proliferationDOID:145661740.021
organ system cancerDOID:00506861640.019
cancerDOID:1621670.019
cardiovascular system diseaseDOID:12871060.019
connective tissue diseaseDOID:651090.015
bone diseaseDOID:0080001880.015
myopathyDOID:4231040.015
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.015
auditory system diseaseDOID:2742530.015
eye and adnexa diseaseDOID:14921500.014
inherited metabolic disorderDOID:6552420.014
neurodegenerative diseaseDOID:12891020.013
neuropathyDOID:870520.012
heart diseaseDOID:114680.012
brain diseaseDOID:936730.011
nonsyndromic deafnessDOID:0050563500.011
eye diseaseDOID:56141490.010