Homo sapiens

35 known processes

EIF4G2

eukaryotic translation initiation factor 4 gamma, 2

(Aliases: FLJ41344,NAT1,DAP5,AAG1,P97)

EIF4G2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
translationGO:00064121320.794
translational initiationGO:0006413480.781
multicellular organismal agingGO:001025930.722
regulation of translational initiationGO:0006446240.582
determination of adult lifespanGO:000834020.581
cellular response to dna damage stimulusGO:00069743790.517
regulation of translational initiation in response to stressGO:004355810.377
spindle elongationGO:005123140.354
mitotic cell cycleGO:00002783260.330
mitotic spindle elongationGO:000002240.328
rna splicingGO:00083801310.301
post embryonic developmentGO:000979120.279
mrna splicing via spliceosomeGO:0000398890.227
rna splicing via transesterification reactionsGO:0000375900.226
regulation of cell differentiationGO:00455953930.224
formation of translation preinitiation complexGO:000173140.214
mrna processingGO:00063971330.210
posttranscriptional regulation of gene expressionGO:00106082130.161
stem cell differentiationGO:0048863930.154
regenerationGO:003109940.153
mrna metabolic processGO:00160711750.147
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.141
positive regulation of developmental processGO:00510943140.140
regulation of translationGO:0006417890.134
protein autophosphorylationGO:00467771230.120
mitotic nuclear divisionGO:00070671190.116
dorsal ventral axis specificationGO:000995070.111
growthGO:00400072020.105
purine ribonucleoside triphosphate metabolic processGO:00092054110.099
purine ribonucleoside catabolic processGO:00461303980.096
female gamete generationGO:000729220.087
ribonucleoside catabolic processGO:00424544060.086
negative regulation of cell differentiationGO:00455961710.084
organelle fissionGO:00482851490.081
negative regulation of developmental processGO:00510932470.080
agingGO:0007568660.076
microtubule cytoskeleton organizationGO:00002261760.075
purine ribonucleoside monophosphate catabolic processGO:00091691580.074
apoptotic signaling pathwayGO:00971902680.073
regulation of mrna metabolic processGO:1903311530.073
regulation of rna splicingGO:0043484620.073
nucleoside monophosphate catabolic processGO:00091251590.073
ribonucleoside monophosphate catabolic processGO:00091581580.071
anatomical structure formation involved in morphogenesisGO:00486462840.071
cellular amino acid metabolic processGO:00065201160.070
lipid localizationGO:00108761060.070
glycosyl compound catabolic processGO:19016584130.069
purine ribonucleoside triphosphate catabolic processGO:00092073910.068
nucleoside triphosphate catabolic processGO:00091433940.066
reproductive processGO:00224141060.066
male sex differentiationGO:0046661250.065
nucleoside catabolic processGO:00091644080.065
purine nucleoside catabolic processGO:00061523980.065
dna repairGO:00062811980.064
mitotic cell cycle processGO:19030472860.063
regulation of cellular amine metabolic processGO:0033238110.063
cellular macromolecule catabolic processGO:00442653800.057
maintenance of locationGO:00512351120.057
response to organic cyclic compoundGO:00140702040.056
spermatid developmentGO:000728640.055
purine nucleoside triphosphate metabolic processGO:00091444120.053
ribonucleoprotein complex assemblyGO:0022618780.051
purine containing compound catabolic processGO:00725234110.051
ribonucleoside triphosphate catabolic processGO:00092033910.050
immune responseGO:00069553070.049
microtubule organizing center organizationGO:0031023620.048
regulation of cell cycleGO:00517263930.048
ribonucleoside monophosphate metabolic processGO:00091611870.046
spindle organizationGO:0007051530.045
centrosome organizationGO:0051297580.045
positive regulation of hydrolase activityGO:00513453310.044
atp catabolic processGO:00062001570.044
alternative mrna splicing via spliceosomeGO:0000380270.043
spermatid differentiationGO:004851540.043
positive regulation of cell cycleGO:00457871400.042
nucleotide catabolic processGO:00091664080.042
innate immune responseGO:00450871780.042
negative regulation of cell deathGO:00605483450.041
regulation of stress activated protein kinase signaling cascadeGO:0070302850.041
mitotic spindle organizationGO:0007052270.041
signal transduction by phosphorylationGO:00230142970.039
regulation of response to dna damage stimulusGO:2001020940.039
response to virusGO:00096151260.038
cellular macromolecular complex assemblyGO:00346223240.038
nuclear divisionGO:00002801280.037
chordate embryonic developmentGO:0043009340.037
purine nucleotide catabolic processGO:00061954050.037
positive regulation of mapk cascadeGO:00434101900.036
microtubule based processGO:00070172100.036
regulation of translation in response to stressGO:004355530.035
stress activated protein kinase signaling cascadeGO:0031098940.034
photoreceptor cell differentiationGO:004653020.034
chromatin organizationGO:00063253510.034
response to biotic stimulusGO:00096072760.033
nucleoside phosphate catabolic processGO:19012924120.033
regulation of mrna processingGO:0050684480.033
stress activated mapk cascadeGO:0051403930.033
regulation of endopeptidase activityGO:00525481700.032
response to other organismGO:00517072610.032
amine metabolic processGO:0009308440.032
positive regulation of transferase activityGO:00513472270.031
cellular response to endogenous stimulusGO:00714953360.031
mapk cascadeGO:00001652880.031
nucleoside monophosphate metabolic processGO:00091231910.030
embryo developmentGO:00097901230.030
negative regulation of cell cycleGO:00457861930.030
regulation of cellular response to stressGO:00801352440.030
positive regulation of immune system processGO:00026842830.030
positive regulation of protein phosphorylationGO:00019343130.030
oogenesisGO:004847720.029
atp metabolic processGO:00460341760.029
regulation of mrna splicing via spliceosomeGO:0048024320.029
purine ribonucleoside monophosphate metabolic processGO:00091671860.029
negative regulation of catalytic activityGO:00430863350.028
regulation of growthGO:00400081650.028
cardiovascular system developmentGO:00723582620.028
cellular ketone metabolic processGO:0042180800.028
regulation of stress activated mapk cascadeGO:0032872840.028
positive regulation of response to dna damage stimulusGO:2001022430.027
regulation of apoptotic signaling pathwayGO:20012331750.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
negative regulation of protein metabolic processGO:00512483910.027
nucleoside triphosphate metabolic processGO:00091414220.026
positive regulation of kinase activityGO:00336742040.026
response to external biotic stimulusGO:00432072610.026
immune system developmentGO:00025201950.026
purine ribonucleotide catabolic processGO:00091544040.026
cell developmentGO:00484683280.026
development of primary male sexual characteristicsGO:0046546230.025
compound eye developmentGO:004874910.025
organophosphate catabolic processGO:00464344300.025
regulation of protein kinase activityGO:00458592890.025
positive regulation of apoptotic processGO:00430652460.025
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.024
oocyte differentiationGO:000999420.024
negative regulation of cellular protein metabolic processGO:00322693530.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
positive regulation of peptidase activityGO:0010952880.024
positive regulation of cellular amine metabolic processGO:003324070.024
dorsal ventral pattern formationGO:0009953150.024
organophosphate biosynthetic processGO:00904071630.024
organonitrogen compound biosynthetic processGO:19015662000.024
negative regulation of apoptotic processGO:00430663160.023
secretionGO:00469032540.023
carbohydrate derivative biosynthetic processGO:19011372070.023
regulation of cellular component biogenesisGO:00440872810.023
regulation of peptidase activityGO:00525471800.023
single organism reproductive processGO:0044702980.023
regulation of cellular amino acid metabolic processGO:000652160.023
neuron fate commitmentGO:004866320.023
regulation of cellular ketone metabolic processGO:0010565500.023
negative regulation of cellular component organizationGO:00511292350.023
male gonad developmentGO:0008584230.022
cytoplasmic transportGO:00164823790.022
protein modification by small protein conjugationGO:00324463420.022
protein maturationGO:00516042330.022
stem cell maintenanceGO:0019827190.022
negative regulation of androgen receptor activityGO:200082420.022
cellular response to cytokine stimulusGO:00713451810.022
regulation of mapk cascadeGO:00434082620.022
cation homeostasisGO:00550801890.022
regulation of meiotic cell cycleGO:005144540.022
mitotic cell cycle phase transitionGO:00447721620.022
negative regulation of phosphorus metabolic processGO:00105632670.021
purine ribonucleoside metabolic processGO:00461284370.021
regulation of cell cycle processGO:00105642660.021
stem cell developmentGO:0048864690.021
positive regulation of programmed cell deathGO:00430682490.021
cell morphogenesisGO:00009022960.021
rna processingGO:00063962550.021
regulation of anatomical structure morphogenesisGO:00226032860.021
regulation of multicellular organism growthGO:004001480.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
negative regulation of cell growthGO:0030308830.021
blastocyst formationGO:000182530.020
positive regulation of growthGO:0045927580.020
positive regulation of cell differentiationGO:00455972110.020
meiotic chromosome segregationGO:004513240.020
hemopoiesisGO:00300971800.020
positive regulation of stress activated mapk cascadeGO:0032874600.020
matingGO:000761810.020
regulation of kinase activityGO:00435493140.020
neurogenesisGO:00220081690.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
ribonucleotide catabolic processGO:00092614050.020
cellular amine metabolic processGO:0044106410.019
regulation of protein complex assemblyGO:00432541470.019
regulation of dna metabolic processGO:00510521530.019
response to oxygen containing compoundGO:19017003690.019
cellular response to oxygen containing compoundGO:19017012760.019
negative regulation of cell cycle processGO:00109481210.019
regulation of response to external stimulusGO:00321012220.019
cell growthGO:00160491600.019
positive regulation of phosphorylationGO:00423273940.019
cell fate determinationGO:000170930.019
cell cycle checkpointGO:00000751170.019
regulation of cell motilityGO:20001452990.019
negative regulation of protein modification processGO:00314002000.019
cell adhesionGO:00071553250.019
histone modificationGO:00165702510.019
positive regulation of transportGO:00510503360.018
regulation of epithelial cell migrationGO:0010632930.018
cytoplasmic translational initiationGO:000218360.018
regulation of cell growthGO:00015581350.018
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.018
positive regulation of nf kappab transcription factor activityGO:0051092810.018
pattern specification processGO:0007389430.018
regulation of cytokine productionGO:00018172320.018
regulation of proteolysisGO:00301622930.018
protein modification by small protein removalGO:0070646920.018
interspecies interaction between organismsGO:00444191560.018
positive regulation of cellular component organizationGO:00511303760.017
cation transmembrane transportGO:00986552380.017
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
regulation of osteoblast differentiationGO:0045667380.017
blood vessel morphogenesisGO:00485141620.017
regionalizationGO:0003002290.017
dephosphorylationGO:00163112090.017
regulation of transferase activityGO:00513383550.017
negative regulation of intracellular signal transductionGO:19025321830.017
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.017
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.017
ribonucleotide biosynthetic processGO:0009260810.017
cytokine mediated signaling pathwayGO:00192211090.017
cellular response to abiotic stimulusGO:00712141170.016
organelle inheritanceGO:004830820.016
intracellular mrna localizationGO:000829810.016
regulation of vasculature developmentGO:1901342970.016
nucleic acid phosphodiester bond hydrolysisGO:00903051020.016
endosomal transportGO:00161971290.016
multi organism reproductive processGO:0044703540.016
cell cycle phase transitionGO:00447701730.016
positive regulation of protein kinase activityGO:00458601900.016
tissue migrationGO:00901301190.016
metal ion transportGO:00300012720.016
purine nucleoside monophosphate catabolic processGO:00091281580.016
regulation of protein processingGO:00706131500.016
cation transportGO:00068123310.016
macromolecular complex disassemblyGO:0032984600.016
sequestering of metal ionGO:0051238240.016
negative regulation of cellular amino acid metabolic processGO:004576320.015
locomotory behaviorGO:000762610.015
jnk cascadeGO:0007254800.015
transmembrane transportGO:00550853990.015
inorganic ion transmembrane transportGO:00986602310.015
protein targetingGO:00066051870.015
positive regulation of apoptotic signaling pathwayGO:2001235700.015
oocyte developmentGO:004859910.015
regulation of jnk cascadeGO:0046328730.015
regulation of secretion by cellGO:19035301770.015
neuromuscular junction developmentGO:000752830.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
developmental process involved in reproductionGO:0003006660.015
protein catabolic processGO:00301633250.015
multi organism cellular processGO:00447641560.015
positive regulation of cytokine productionGO:00018191670.015
angiogenesisGO:00015251470.015
system processGO:00030083490.015
phospholipid metabolic processGO:0006644990.014
negative regulation of cellular amine metabolic processGO:003323930.014
positive regulation of endopeptidase activityGO:0010950840.014
positive regulation of smoothened signaling pathwayGO:004588040.014
regulation of mitotic cell cycleGO:00073461890.014
wnt signaling pathwayGO:00160551560.014
positive regulation of cysteine type endopeptidase activityGO:2001056790.014
positive regulation of catabolic processGO:00098963100.014
neural tube formationGO:000184130.014
positive regulation of cellular component movementGO:00512721810.014
positive regulation of organelle organizationGO:00106381950.014
rna catabolic processGO:0006401710.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.014
regulation of meiosisGO:004002030.014
negative regulation of hydrolase activityGO:00513461820.014
positive regulation of cell deathGO:00109422630.014
negative regulation of multicellular organismal processGO:00512413170.014
guanosine containing compound catabolic processGO:19010692390.014
eye photoreceptor cell differentiationGO:000175420.014
glycoprotein biosynthetic processGO:0009101910.014
protein secretionGO:0009306980.014
regulation of defense responseGO:00313471540.014
secretion by cellGO:00329402260.014
syncytium formation by plasma membrane fusionGO:000076820.013
sex determinationGO:000753030.013
actin filament based processGO:00300292240.013
neurotransmitter secretionGO:000726940.013
negative regulation of cell cycle phase transitionGO:1901988890.013
regulation of neurotransmitter secretionGO:004692830.013
sequestering of calcium ionGO:0051208170.013
negative regulation of transferase activityGO:00513481240.013
protein localization to membraneGO:00726571600.013
reproductionGO:0000003630.013
ossificationGO:00015031210.013
lymphocyte homeostasisGO:000226040.013
response to abiotic stimulusGO:00096283360.013
dna damage checkpointGO:0000077680.013
single organism cell adhesionGO:00986021790.013
positive regulation of proteolysisGO:00458621420.013
protein processingGO:00164852260.013
reproductive structure developmentGO:0048608550.013
negative regulation of phosphate metabolic processGO:00459362670.013
cellular protein catabolic processGO:00442572610.013
positive regulation of cell motilityGO:20001471770.013
peptidyl tyrosine phosphorylationGO:00181081700.013
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
inorganic cation transmembrane transportGO:00986621940.013
lipid metabolic processGO:00066293810.013
cellular response to lipidGO:00713961270.013
muscle contractionGO:0006936730.013
gtp catabolic processGO:00061842370.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of dephosphorylationGO:0035303960.012
ion transmembrane transportGO:00342203380.012
cellular response to growth factor stimulusGO:00713631970.012
negative regulation of multi organism processGO:0043901920.012
anterior posterior axis specificationGO:000994820.012
activation of immune responseGO:00022531140.012
tissue morphogenesisGO:0048729960.012
single organism carbohydrate metabolic processGO:00447231930.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
t cell activationGO:0042110990.012
meiosis iGO:000712740.012
lens development in camera type eyeGO:000208820.012
cytokine productionGO:00018162470.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.012
protein ubiquitinationGO:00165673140.012
positive regulation of cell proliferationGO:00082843010.012
regulation of wnt signaling pathwayGO:00301111230.012
negative regulation of endopeptidase activityGO:0010951840.012
cytoplasmic translationGO:000218180.012
regulation of dna repairGO:0006282470.012
dna conformation changeGO:00711031130.012
negative regulation of protein maturationGO:19033181420.012
negative regulation of cell proliferationGO:00082852280.012
positive regulation of secretionGO:00510471160.012
morphogenesis of embryonic epitheliumGO:001633140.012
tissue regenerationGO:004224630.012
segmentationGO:003528240.012
positive regulation of locomotionGO:00400171860.012
single organism cellular localizationGO:19025803320.012
cell projection assemblyGO:00300311260.012
double strand break repairGO:00063021010.012
signal transduction by p53 class mediatorGO:0072331720.012
viral life cycleGO:00190581320.012
circadian behaviorGO:004851220.012
response to radiationGO:00093141510.012
biological adhesionGO:00226103310.012
regulation of protein stabilityGO:0031647870.012
blastocyst developmentGO:000182430.012
metal ion homeostasisGO:00550651690.012
nucleocytoplasmic transportGO:00069131760.012
negative regulation of growthGO:0045926970.012
negative regulation of apoptotic signaling pathwayGO:2001234970.011
positive regulation of meiotic cell cycleGO:005144620.011
regulation of ion transportGO:00432691890.011
somatic muscle developmentGO:000752510.011
glycosylationGO:0070085710.011
nucleotide biosynthetic processGO:00091651090.011
regulation of purine nucleotide metabolic processGO:19005422640.011
cell cycle g1 s phase transitionGO:0044843800.011
purine containing compound biosynthetic processGO:0072522880.011
epithelium migrationGO:00901321190.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
regulation of secretionGO:00510461940.011
somitogenesisGO:000175620.011
protein deubiquitinationGO:0016579790.011
negative regulation of kinase activityGO:00336731060.011
autophagic cell deathGO:004810230.011
peptidyl tyrosine modificationGO:00182121700.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
myoblast fusionGO:000752010.011
positive regulation of multicellular organism growthGO:004001860.011
regulation of organelle assemblyGO:1902115400.011
positive regulation of dna metabolic processGO:0051054730.011
regulation of multi organism processGO:00439001570.011
regulation of locomotionGO:00400123290.011
negative regulation of protein processingGO:00109551420.011
osteoblast differentiationGO:0001649920.011
actin cytoskeleton organizationGO:00300362070.011
negative regulation of protein phosphorylationGO:00019331400.011
response to cytokineGO:00340972320.011
response to salt stressGO:000965130.011
chronological cell agingGO:000130020.011
urogenital system developmentGO:0001655650.011
muscle structure developmentGO:0061061980.011
cerebellum developmentGO:002154920.011
negative regulation of phosphorylationGO:00423261740.011
positive regulation of jnk cascadeGO:0046330520.011
rhythmic behaviorGO:000762220.011
protein complex disassemblyGO:0043241520.011
positive regulation of immune responseGO:00507781590.011
synaptic transmission cholinergicGO:000727120.011
kidney developmentGO:0001822530.011
negative regulation of glial cell proliferationGO:006025320.011
regulation of homeostatic processGO:00328441210.011
nuclear transportGO:00511691790.011
nephron developmentGO:0072006300.010
carbohydrate metabolic processGO:00059752070.010
regulation of cellular component movementGO:00512703340.010
regulation of cytoskeleton organizationGO:00514931770.010
plasma membrane organizationGO:00070091150.010
establishment of protein localization to membraneGO:00901501210.010
regulation of innate immune responseGO:0045088970.010
dna integrity checkpointGO:0031570710.010
striated muscle contractionGO:0006941520.010
limbic system developmentGO:002176130.010
positive regulation of mitotic cell cycleGO:0045931600.010
cardiac muscle contractionGO:0060048340.010
regulation of alternative mrna splicing via spliceosomeGO:0000381220.010
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063330.010
blood vessel developmentGO:00015681720.010
retina vasculature development in camera type eyeGO:006129830.010
cellular component disassemblyGO:0022411920.010
epithelial cell migrationGO:00106311190.010
motor neuron axon guidanceGO:000804520.010
ion homeostasisGO:00508012300.010
protein polyubiquitinationGO:00002091100.010
mitochondrion organizationGO:00070051560.010
glycoprotein metabolic processGO:00091001100.010
reactive nitrogen species metabolic processGO:200105730.010
negative regulation of protein kinase activityGO:0006469980.010
positive regulation of cytoplasmic transportGO:1903651820.010
positive regulation of cell migrationGO:00303351720.010

EIF4G2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.027
central nervous system diseaseDOID:3311860.027
neurodegenerative diseaseDOID:12891020.026
parkinson s diseaseDOID:14330180.026
synucleinopathyDOID:0050890220.026
disease of mental healthDOID:150700.022
disease of metabolismDOID:00146672950.018
developmental disorder of mental healthDOID:0060037290.017
musculoskeletal system diseaseDOID:172230.016
sensory system diseaseDOID:00501552030.014
auditory system diseaseDOID:2742530.014
muscular diseaseDOID:00800001140.012
immune system diseaseDOID:29141550.011
eye and adnexa diseaseDOID:14921500.010
eye diseaseDOID:56141490.010
disease of cellular proliferationDOID:145661740.010
cancerDOID:1621670.010