Homo sapiens

100 known processes

E2F8

E2F transcription factor 8

(Aliases: FLJ23311,E2F-8)

E2F8 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
hepatocyte differentiationGO:007036510.986
Mouse
sprouting angiogenesisGO:0002040290.942
negative regulation of cytokinesisGO:003246630.900
Mouse
dna dependent dna replicationGO:0006261440.749
Mouse
dna replicationGO:00062601160.745
Mouse
positive regulation of dna metabolic processGO:0051054730.743
Mouse
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:000008380.738
Human
dna damage response signal transduction by p53 class mediatorGO:0030330440.689
Human
positive regulation of dna replicationGO:0045740350.622
Mouse
vasculature developmentGO:00019441810.579
cardiovascular system developmentGO:00723582620.564
positive regulation of cell cycleGO:00457871400.542
Mouse
negative regulation of cell proliferationGO:00082852280.535
Human
signal transduction in response to dna damageGO:0042770570.511
Human
blood vessel developmentGO:00015681720.450
blood vessel morphogenesisGO:00485141620.433
positive regulation of cell cycle processGO:00900681060.428
Mouse
regulation of cytokinesisGO:0032465450.421
Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.419
regulation of dna endoreduplicationGO:003287550.419
Mouse
angiogenesisGO:00015251470.398
g1 s transition of mitotic cell cycleGO:0000082780.389
Human
cytokinesisGO:0000910960.317
Mouse
cell cycle g1 s phase transitionGO:0044843800.307
Human
regulation of cell cycleGO:00517263930.301
Mouse
negative regulation of cell cycle processGO:00109481210.295
Mouse
negative regulation of cell cycleGO:00457861930.292
Mouse
regulation of dna replicationGO:0006275680.287
Mouse
negative regulation of mitotic cell cycle phase transitionGO:1901991850.286
mitotic cell cycle phase transitionGO:00447721620.278
Human
cell cycle phase transitionGO:00447701730.255
Human
gland developmentGO:0048732480.253
Mouse
regulation of cell divisionGO:00513021160.243
Mouse
epithelium developmentGO:00604292270.242
Mouse
negative regulation of cell cycle g1 s phase transitionGO:1902807290.240
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.235
mitotic cell cycleGO:00002783260.218
Human Mouse
mitotic cell cycle processGO:19030472860.203
Human
post embryonic developmentGO:000979120.203
regulation of dna dependent dna replicationGO:0090329190.203
Mouse
negative regulation of cell divisionGO:0051782310.185
Mouse
regulation of mitotic cell cycleGO:00073461890.179
hepaticobiliary system developmentGO:0061008100.178
Mouse
chordate embryonic developmentGO:0043009340.171
Mouse
regulation of g1 s transition of mitotic cell cycleGO:2000045400.170
placenta developmentGO:0001890100.167
Mouse
negative regulation of cell cycle phase transitionGO:1901988890.166
negative regulation of mitotic cell cycleGO:00459301020.158
embryonic organ developmentGO:0048568360.150
Mouse
regulation of cell cycle phase transitionGO:19019871260.128
regulation of mitotic cell cycle phase transitionGO:19019901180.114
regulation of cell differentiationGO:00455953930.080
cellular amino acid metabolic processGO:00065201160.076
amine metabolic processGO:0009308440.071
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.067
chromatin organizationGO:00063253510.066
reproductive processGO:00224141060.062
Mouse
cellular response to dna damage stimulusGO:00069743790.061
Human
cell cycle dna replicationGO:0044786110.059
Mouse
regulation of cellular amine metabolic processGO:0033238110.057
reproductive system developmentGO:0061458560.057
Mouse
dna repairGO:00062811980.056
cellular component morphogenesisGO:00329893140.055
single organism reproductive processGO:0044702980.055
Mouse
regulation of cellular amino acid metabolic processGO:000652160.054
purine containing compound catabolic processGO:00725234110.054
cell developmentGO:00484683280.052
response to abiotic stimulusGO:00096283360.049
regulation of cell cycle processGO:00105642660.047
Mouse
dna conformation changeGO:00711031130.047
cellular ketone metabolic processGO:0042180800.044
regulation of cellular ketone metabolic processGO:0010565500.042
cellular amine metabolic processGO:0044106410.042
negative regulation of programmed cell deathGO:00430693210.042
immune system developmentGO:00025201950.041
oogenesisGO:004847720.041
reproductive structure developmentGO:0048608550.041
Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.041
nucleoside phosphate catabolic processGO:19012924120.040
purine ribonucleoside metabolic processGO:00461284370.040
embryo development ending in birth or egg hatchingGO:0009792340.040
Mouse
nucleoside triphosphate metabolic processGO:00091414220.039
hemopoiesisGO:00300971800.039
wnt signaling pathwayGO:00160551560.038
immune responseGO:00069553070.038
cell projection organizationGO:00300302520.037
purine nucleotide catabolic processGO:00061954050.036
female gamete generationGO:000729220.036
positive regulation of cell differentiationGO:00455972110.035
ribonucleotide catabolic processGO:00092614050.035
nervous system developmentGO:00073992930.035
negative regulation of phosphate metabolic processGO:00459362670.035
positive regulation of apoptotic processGO:00430652460.035
positive regulation of cellular amino acid metabolic processGO:004576430.034
negative regulation of protein metabolic processGO:00512483910.033
multicellular organismal agingGO:001025930.033
regulation of dna metabolic processGO:00510521530.032
Mouse
cytoplasmic transportGO:00164823790.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
regulation of proteolysisGO:00301622930.031
positive regulation of cellular amine metabolic processGO:003324070.031
positive regulation of hydrolase activityGO:00513453310.030
regulation of protein localizationGO:00328802960.030
positive regulation of catabolic processGO:00098963100.030
positive regulation of programmed cell deathGO:00430682490.030
positive regulation of cellular component organizationGO:00511303760.030
purine nucleoside catabolic processGO:00061523980.029
neurogenesisGO:00220081690.029
regulation of protein transportGO:00512232130.028
vesicle mediated transportGO:00161923710.028
protein dna complex subunit organizationGO:0071824800.028
locomotory behaviorGO:000762610.027
intracellular protein transportGO:00068862700.027
determination of adult lifespanGO:000834020.027
single organism cellular localizationGO:19025803320.027
purine ribonucleoside catabolic processGO:00461303980.027
cellular lipid metabolic processGO:00442553030.027
regulation of establishment of protein localizationGO:00702012420.027
purine nucleoside triphosphate metabolic processGO:00091444120.027
negative regulation of cellular protein metabolic processGO:00322693530.026
protein localization to organelleGO:00333652800.026
transmembrane transportGO:00550853990.026
glycosyl compound catabolic processGO:19016584130.026
purine ribonucleoside triphosphate metabolic processGO:00092054110.026
embryo developmentGO:00097901230.025
Mouse
negative regulation of apoptotic processGO:00430663160.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
membrane organizationGO:00610242920.025
dna endoreduplicationGO:004202350.025
Mouse
apoptotic signaling pathwayGO:00971902680.025
ras protein signal transductionGO:0007265730.024
regulation of kinase activityGO:00435493140.024
single organism membrane organizationGO:00448022680.024
negative regulation of multicellular organismal processGO:00512413170.024
myeloid cell differentiationGO:00300991170.024
positive regulation of cellular catabolic processGO:00313312840.023
gtp metabolic processGO:00460392390.023
generation of neuronsGO:00486991520.023
maintenance of locationGO:00512351120.023
positive regulation of protein phosphorylationGO:00019343130.022
regulation of cell morphogenesisGO:00226041530.022
covalent chromatin modificationGO:00165692540.022
cellular macromolecule catabolic processGO:00442653800.022
protein catabolic processGO:00301633250.022
positive regulation of cell deathGO:00109422630.022
regulation of peptidase activityGO:00525471800.022
cell fate determinationGO:000170930.022
defense responseGO:00069523150.021
response to oxygen containing compoundGO:19017003690.021
cellular macromolecular complex assemblyGO:00346223240.021
positive regulation of transportGO:00510503360.021
signal transduction by phosphorylationGO:00230142970.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
lipid metabolic processGO:00066293810.021
small gtpase mediated signal transductionGO:0007264780.021
negative regulation of cell deathGO:00605483450.021
regulation of cellular component biogenesisGO:00440872810.020
cellular response to oxygen containing compoundGO:19017012760.020
negative regulation of cell differentiationGO:00455961710.020
negative regulation of cellular component organizationGO:00511292350.020
chromatin assembly or disassemblyGO:0006333780.020
neuromuscular junction developmentGO:000752830.020
epithelial cell proliferationGO:00506731280.020
regulation of nucleotide catabolic processGO:00308112050.020
organophosphate catabolic processGO:00464344300.020
chemical homeostasisGO:00488783060.020
protein targetingGO:00066051870.020
regenerationGO:003109940.020
endomembrane system organizationGO:00102561960.020
growthGO:00400072020.019
positive regulation of immune system processGO:00026842830.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
mapk cascadeGO:00001652880.019
regulation of cellular response to stressGO:00801352440.019
chromatin modificationGO:00165682980.019
cell morphogenesisGO:00009022960.019
regulation of nucleoside metabolic processGO:00091182090.019
negative regulation of protein modification processGO:00314002000.019
protein dna complex assemblyGO:0065004640.019
regulation of transferase activityGO:00513383550.019
regulation of nucleotide metabolic processGO:00061402690.019
negative regulation of intracellular signal transductionGO:19025321830.019
negative regulation of hydrolase activityGO:00513461820.019
regulation of cell motilityGO:20001452990.018
negative regulation of catalytic activityGO:00430863350.018
organ morphogenesisGO:00098871470.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
positive regulation of cell proliferationGO:00082843010.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
oocyte developmentGO:004859910.018
ribonucleoside catabolic processGO:00424544060.018
actin filament based processGO:00300292240.018
circulatory system developmentGO:00723592620.018
histone modificationGO:00165702510.017
carbohydrate metabolic processGO:00059752070.017
regulation of cellular component movementGO:00512703340.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
peripheral nervous system developmentGO:000742220.017
guanosine containing compound metabolic processGO:19010682440.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
biological adhesionGO:00226103310.017
nuclear transportGO:00511691790.017
cell divisionGO:00513011680.017
Mouse
regulation of purine nucleotide metabolic processGO:19005422640.017
protein ubiquitinationGO:00165673140.017
nitrogen compound transportGO:00717051910.017
ion transmembrane transportGO:00342203380.016
regulation of intracellular transportGO:00323861950.016
regulation of gtpase activityGO:00430871800.016
positive regulation of organelle organizationGO:00106381950.016
positive regulation of nucleotide metabolic processGO:00459812300.016
rna processingGO:00063962550.016
response to lipidGO:00339932060.016
nucleotide catabolic processGO:00091664080.016
cell growthGO:00160491600.016
oxidation reduction processGO:00551143960.016
regulation of cytoplasmic transportGO:19036491490.016
regulation of purine nucleotide catabolic processGO:00331212050.016
regulation of bindingGO:00510981110.016
response to oxidative stressGO:00069791210.016
endocytosisGO:00068971590.016
organelle assemblyGO:00709251760.016
organonitrogen compound biosynthetic processGO:19015662000.016
ion homeostasisGO:00508012300.016
system processGO:00030083490.016
neuron differentiationGO:00301821380.015
cell part morphogenesisGO:00329901370.015
regulation of protein complex assemblyGO:00432541470.015
innate immune responseGO:00450871780.015
regulation of cell migrationGO:00303342890.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
negative regulation of phosphorus metabolic processGO:00105632670.015
purine ribonucleotide catabolic processGO:00091544040.015
guanosine containing compound catabolic processGO:19010692390.015
gtp catabolic processGO:00061842370.015
brain developmentGO:0007420970.015
positive regulation of phosphorylationGO:00423273940.015
carbohydrate derivative biosynthetic processGO:19011372070.015
metal ion transportGO:00300012720.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
secretionGO:00469032540.015
segmentationGO:003528240.015
nucleoside catabolic processGO:00091644080.015
regulation of wnt signaling pathwayGO:00301111230.015
regulation of epithelial cell proliferationGO:00506781130.015
regulation of multi organism processGO:00439001570.015
rho protein signal transductionGO:0007266260.015
regulation of apoptotic signaling pathwayGO:20012331750.015
positive regulation of protein kinase activityGO:00458601900.015
spermatid differentiationGO:004851540.015
secretion by cellGO:00329402260.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.015
response to light stimulusGO:0009416870.014
cellular response to growth factor stimulusGO:00713631970.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
response to external biotic stimulusGO:00432072610.014
cellular response to endogenous stimulusGO:00714953360.014
dna recombinationGO:0006310770.014
protein oligomerizationGO:00512591730.014
hindbrain developmentGO:003090230.014
protein homooligomerizationGO:00512601000.014
neuron developmentGO:00486661130.014
cellular response to oxidative stressGO:0034599850.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
regulation of cell growthGO:00015581350.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
nucleocytoplasmic transportGO:00069131760.014
regulation of response to external stimulusGO:00321012220.014
regulation of immune responseGO:00507762010.014
regulation of protein kinase activityGO:00458592890.014
positive regulation of protein transportGO:00512221350.014
spermatid developmentGO:000728640.014
interspecies interaction between organismsGO:00444191560.014
oocyte differentiationGO:000999420.013
single organism carbohydrate metabolic processGO:00447231930.013
positive regulation of nucleotide catabolic processGO:00308131850.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
positive regulation of gtpase activityGO:00435471660.013
nucleoside triphosphate catabolic processGO:00091433940.013
protein modification by small protein conjugationGO:00324463420.013
protein importGO:00170381300.013
epithelial cell differentiationGO:00308551410.013
Mouse
establishment of protein localization to organelleGO:00725941720.013
regulation of protein serine threonine kinase activityGO:00719001790.013
negative regulation of phosphorylationGO:00423261740.013
regulation of gene expression epigeneticGO:0040029730.013
immune effector processGO:00022521590.013
actin cytoskeleton organizationGO:00300362070.013
response to other organismGO:00517072610.013
chemotaxisGO:00069351570.013
adult locomotory behaviorGO:000834410.013
posttranscriptional regulation of gene expressionGO:00106082130.013
protein maturationGO:00516042330.013
regulation of chromosome organizationGO:00330441030.013
regulation of secretion by cellGO:19035301770.013
cellular protein catabolic processGO:00442572610.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of secretionGO:00510461940.013
peptidyl tyrosine modificationGO:00182121700.013
protein processingGO:00164852260.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
monocarboxylic acid metabolic processGO:00327871850.013
head developmentGO:00603221080.013
positive regulation of nucleoside metabolic processGO:00459791860.012
cation transmembrane transportGO:00986552380.012
chromatin assemblyGO:0031497610.012
neuron projection developmentGO:00311751060.012
positive regulation of developmental processGO:00510943140.012
cell activationGO:00017752130.012
dephosphorylationGO:00163112090.012
reactive oxygen species metabolic processGO:0072593750.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
negative regulation of transportGO:00510511760.012
protein localization to nucleusGO:00345041360.012
blastocyst developmentGO:000182430.012
response to woundingGO:00096111680.012
response to biotic stimulusGO:00096072760.012
cellular protein complex assemblyGO:00436231880.012
positive regulation of gtp catabolic processGO:00331261660.012
negative regulation of transferase activityGO:00513481240.012
regulation of cytoskeleton organizationGO:00514931770.012
regulation of mapk cascadeGO:00434082620.012
organophosphate biosynthetic processGO:00904071630.012
negative regulation of protein phosphorylationGO:00019331400.012
double strand break repairGO:00063021010.012
positive regulation of proteolysisGO:00458621420.012
morphogenesis of embryonic epitheliumGO:001633140.012
cell projection assemblyGO:00300311260.012
ribonucleoside monophosphate metabolic processGO:00091611870.011
regulation of gtp catabolic processGO:00331241800.011
regulation of protein maturationGO:19033171500.011
i kappab kinase nf kappab signalingGO:00072491660.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
microtubule based processGO:00070172100.011
cation transportGO:00068123310.011
response to inorganic substanceGO:00100351270.011
positive regulation of locomotionGO:00400171860.011
regulation of anatomical structure sizeGO:00900661010.011
lymphocyte activationGO:00466491330.011
negative regulation of cellular amine metabolic processGO:003323930.011
neurological system processGO:00508771630.011
positive regulation of immune responseGO:00507781590.011
viral life cycleGO:00190581320.011
cytokine productionGO:00018162470.011
response to hormoneGO:00097251750.011
response to organonitrogen compoundGO:00102431560.011
single organism cell adhesionGO:00986021790.011
response to cytokineGO:00340972320.011
regulation of intracellular protein transportGO:00331571230.011
atp metabolic processGO:00460341760.011
nerve developmentGO:002167540.011
heart developmentGO:0007507950.011
positive regulation of cellular component biogenesisGO:00440891580.011
response to bacteriumGO:00096171440.011
regulation of hormone levelsGO:00108171250.011
negative regulation of immune system processGO:00026831360.011
embryonic epithelial tube formationGO:000183840.011
regulation of nucleocytoplasmic transportGO:0046822980.011
cellular response to lipidGO:00713961270.011
multi organism cellular processGO:00447641560.011
ubiquitin dependent protein catabolic processGO:00065112060.011
in utero embryonic developmentGO:000170180.011
Mouse
regulation of growthGO:00400081650.011
divalent metal ion transportGO:00708381520.011
response to growth factorGO:00708482050.011
atp catabolic processGO:00062001570.011
regulation of response to dna damage stimulusGO:2001020940.011
cellular response to cytokine stimulusGO:00713451810.010
positive regulation of transferase activityGO:00513472270.010
regulation of defense responseGO:00313471540.010
regulation of protein processingGO:00706131500.010
positive regulation of intracellular transportGO:00323881040.010
regulation of anatomical structure morphogenesisGO:00226032860.010
ameboidal type cell migrationGO:00016671350.010
translationGO:00064121320.010
organelle fissionGO:00482851490.010
cellular component disassemblyGO:0022411920.010
regulation of phosphatase activityGO:0010921810.010
inorganic ion transmembrane transportGO:00986602310.010
nuclear importGO:00511701060.010
cell adhesionGO:00071553250.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
methylationGO:00322591060.010
rna interferenceGO:001624640.010
cation homeostasisGO:00550801890.010

E2F8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.016
disease of metabolismDOID:00146672950.016
central nervous system diseaseDOID:3311860.011
nervous system diseaseDOID:8634310.011
cancerDOID:1621670.010
organ system cancerDOID:00506861640.010
disease of cellular proliferationDOID:145661740.010