Homo sapiens

31 known processes

POLR2E

polymerase (RNA) II (DNA directed) polypeptide E, 25kDa

(Aliases: XAP4,RPABC1,hsRPB5,hRPB25,RPB5)

POLR2E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.615
vesicle mediated transportGO:00161923710.549
receptor mediated endocytosisGO:0006898840.275
transcription from rna polymerase iii promoterGO:0006383190.238
Yeast
endocytosisGO:00068971590.223
negative regulation of apoptotic signaling pathwayGO:2001234970.211
single organism membrane organizationGO:00448022680.193
covalent chromatin modificationGO:00165692540.179
membrane organizationGO:00610242920.178
multicellular organismal agingGO:001025930.146
embryo developmentGO:00097901230.145
Worm
protein localization to organelleGO:00333652800.144
cellular macromolecule catabolic processGO:00442653800.136
cellular macromolecular complex assemblyGO:00346223240.133
reproductive system developmentGO:0061458560.129
Worm
cell developmentGO:00484683280.125
determination of adult lifespanGO:000834020.113
female gamete generationGO:000729220.096
oogenesisGO:004847720.095
cell cell signalingGO:00072671550.093
growthGO:00400072020.093
cellular response to dna damage stimulusGO:00069743790.092
Fly
regulation of growthGO:00400081650.075
regulation of apoptotic signaling pathwayGO:20012331750.075
embryo development ending in birth or egg hatchingGO:0009792340.072
Worm
regulation of cellular amine metabolic processGO:0033238110.071
positive regulation of cellular amine metabolic processGO:003324070.064
chromatin organizationGO:00063253510.062
protein catabolic processGO:00301633250.061
transmembrane transportGO:00550853990.059
cellular lipid metabolic processGO:00442553030.059
posttranscriptional regulation of gene expressionGO:00106082130.058
neurogenesisGO:00220081690.058
reproductive structure developmentGO:0048608550.058
Worm
reproductionGO:0000003630.054
Worm
lipid metabolic processGO:00066293810.049
positive regulation of catabolic processGO:00098963100.049
cellular component morphogenesisGO:00329893140.048
dephosphorylationGO:00163112090.048
regulation of ion transportGO:00432691890.047
establishment of protein localization to membraneGO:00901501210.046
response to organic cyclic compoundGO:00140702040.045
regulation of cell growthGO:00015581350.044
secretion by cellGO:00329402260.042
negative regulation of cell deathGO:00605483450.042
maintenance of locationGO:00512351120.040
regulation of cell cycle processGO:00105642660.040
Fly
response to abiotic stimulusGO:00096283360.040
regulation of cell cycleGO:00517263930.040
Fly
nervous system developmentGO:00073992930.038
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
regulation of gene expression epigeneticGO:0040029730.038
apoptotic signaling pathwayGO:00971902680.036
positive regulation of hydrolase activityGO:00513453310.036
chromatin modificationGO:00165682980.035
regulation of dna metabolic processGO:00510521530.035
dna replicationGO:00062601160.034
negative regulation of apoptotic processGO:00430663160.034
ion transmembrane transportGO:00342203380.032
dna dependent dna replicationGO:0006261440.032
single organism cellular localizationGO:19025803320.032
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.032
reproductive processGO:00224141060.032
Worm
immune responseGO:00069553070.032
response to metal ionGO:0010038840.031
positive regulation of cellular component organizationGO:00511303760.031
neuron differentiationGO:00301821380.031
regulation of protein modification by small protein conjugation or removalGO:19033201070.031
positive regulation of cellular amino acid metabolic processGO:004576430.030
amine metabolic processGO:0009308440.030
protein localization to membraneGO:00726571600.029
single organism reproductive processGO:0044702980.029
Worm
cytoplasmic transportGO:00164823790.029
cellular amine metabolic processGO:0044106410.029
positive regulation of developmental processGO:00510943140.028
divalent inorganic cation transportGO:00725111580.028
ribonucleoside catabolic processGO:00424544060.027
protein targetingGO:00066051870.027
sex differentiationGO:0007548450.027
Worm
mrna metabolic processGO:00160711750.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
cellular ketone metabolic processGO:0042180800.025
gonad developmentGO:0008406340.025
Worm
translationGO:00064121320.025
negative regulation of cell cycle phase transitionGO:1901988890.025
Fly
anatomical structure formation involved in morphogenesisGO:00486462840.025
proteasomal protein catabolic processGO:00104981760.024
ion homeostasisGO:00508012300.024
protein modification by small protein conjugationGO:00324463420.024
nuclear transportGO:00511691790.023
cellular response to organic cyclic compoundGO:00714071270.023
modification dependent protein catabolic processGO:00199412090.023
negative regulation of intracellular signal transductionGO:19025321830.023
secretionGO:00469032540.023
cell projection organizationGO:00300302520.023
response to biotic stimulusGO:00096072760.023
regulation of mapk cascadeGO:00434082620.023
microtubule cytoskeleton organizationGO:00002261760.022
purine ribonucleoside metabolic processGO:00461284370.022
regulation of transporter activityGO:0032409820.022
regulation of nucleotide metabolic processGO:00061402690.022
response to radiationGO:00093141510.022
actin filament based processGO:00300292240.021
developmental process involved in reproductionGO:0003006660.021
Worm
regulation of secretion by cellGO:19035301770.021
cell morphogenesisGO:00009022960.021
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.021
positive regulation of transportGO:00510503360.021
regulation of cellular response to stressGO:00801352440.020
intrinsic apoptotic signaling pathwayGO:00971931270.020
cellular chemical homeostasisGO:00550821800.020
histone acetylationGO:0016573930.020
negative regulation of phosphorus metabolic processGO:00105632670.019
positive regulation of cellular catabolic processGO:00313312840.019
peptidyl lysine acetylationGO:00183941010.019
monocarboxylic acid metabolic processGO:00327871850.019
internal protein amino acid acetylationGO:00064751010.019
protein acylationGO:00435431380.019
nucleotide catabolic processGO:00091664080.019
mitotic cell cycleGO:00002783260.019
Fly
positive regulation of growthGO:0045927580.019
cell divisionGO:00513011680.018
negative regulation of programmed cell deathGO:00430693210.018
ras protein signal transductionGO:0007265730.018
generation of neuronsGO:00486991520.018
peptidyl serine modificationGO:00182091060.018
cellular protein catabolic processGO:00442572610.018
response to oxygen containing compoundGO:19017003690.018
photoreceptor cell differentiationGO:004653020.018
purine nucleoside triphosphate catabolic processGO:00091463920.017
tissue morphogenesisGO:0048729960.017
g2 dna damage checkpointGO:0031572260.017
Fly
establishment of protein localization to organelleGO:00725941720.017
endomembrane system organizationGO:00102561960.017
multi organism reproductive processGO:0044703540.017
metal ion transportGO:00300012720.017
small nucleolar ribonucleoprotein complex assemblyGO:000049130.017
response to inorganic substanceGO:00100351270.016
intracellular protein transportGO:00068862700.016
regulation of transferase activityGO:00513383550.016
organ morphogenesisGO:00098871470.016
negative regulation of cellular protein metabolic processGO:00322693530.016
regulation of cellular amino acid metabolic processGO:000652160.016
response to organonitrogen compoundGO:00102431560.016
ribonucleoprotein complex subunit organizationGO:0071826810.016
neuron developmentGO:00486661130.016
phospholipid metabolic processGO:0006644990.015
cellular protein complex assemblyGO:00436231880.015
cellular amino acid metabolic processGO:00065201160.015
response to hormoneGO:00097251750.015
mrna processingGO:00063971330.015
positive regulation of organelle organizationGO:00106381950.015
regulation of locomotionGO:00400123290.015
calcium ion transportGO:00068161470.015
termination of rna polymerase ii transcriptionGO:000636910.015
positive regulation of cell deathGO:00109422630.015
system processGO:00030083490.015
cellular response to cytokine stimulusGO:00713451810.015
divalent inorganic cation homeostasisGO:00725071360.015
histone modificationGO:00165702510.015
purine nucleotide catabolic processGO:00061954050.015
cellular ion homeostasisGO:00068731680.014
response to virusGO:00096151260.014
biological adhesionGO:00226103310.014
development of primary sexual characteristicsGO:0045137350.014
Worm
innate immune responseGO:00450871780.014
multicellular organism reproductionGO:0032504420.014
ribonucleoside triphosphate catabolic processGO:00092033910.014
cellular response to growth factor stimulusGO:00713631970.014
agingGO:0007568660.014
erk1 and erk2 cascadeGO:00703711040.014
proteolysis involved in cellular protein catabolic processGO:00516032440.013
regulation of dna dependent dna replicationGO:0090329190.013
chemical homeostasisGO:00488783060.013
response to purine containing compoundGO:0014074400.013
protein targeting to nucleusGO:00447441040.013
internal peptidyl lysine acetylationGO:0018393970.013
lipid localizationGO:00108761060.013
cellular response to hormone stimulusGO:00328701250.013
regulation of bindingGO:00510981110.013
negative regulation of protein metabolic processGO:00512483910.013
regulation of purine nucleotide metabolic processGO:19005422640.013
cellular metal ion homeostasisGO:00068751460.013
purine nucleoside catabolic processGO:00061523980.013
fatty acid metabolic processGO:00066311150.013
defense responseGO:00069523150.013
negative regulation of cellular component organizationGO:00511292350.012
rna interferenceGO:001624640.012
regulation of transmembrane transportGO:00347621390.012
response to external biotic stimulusGO:00432072610.012
single organism nuclear importGO:19025931040.012
cellular response to steroid hormone stimulusGO:0071383370.012
nucleocytoplasmic transportGO:00069131760.012
response to lipidGO:00339932060.012
cardiovascular system developmentGO:00723582620.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
dna damage checkpointGO:0000077680.012
Fly
regulation of mitotic cell cycleGO:00073461890.012
Fly
small gtpase mediated signal transductionGO:0007264780.012
dna integrity checkpointGO:0031570710.012
Fly
establishment of organelle localizationGO:0051656590.011
response to temperature stimulusGO:0009266220.011
cellular response to abiotic stimulusGO:00712141170.011
regulation of establishment of protein localizationGO:00702012420.011
response to growth factorGO:00708482050.011
glycosyl compound catabolic processGO:19016584130.011
ribonucleoprotein complex biogenesisGO:00226131160.010
regulation of cell projection organizationGO:00313441070.010
negative regulation of hydrolase activityGO:00513461820.010
sexual reproductionGO:0019953370.010
regulation of intracellular transportGO:00323861950.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
coenzyme metabolic processGO:0006732650.010
response to other organismGO:00517072610.010
locomotory behaviorGO:000762610.010
circulatory system developmentGO:00723592620.010

POLR2E disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.010
cancerDOID:1621670.010