Homo sapiens

31 known processes

POLR2C

polymerase (RNA) II (DNA directed) polypeptide C, 33kDa

(Aliases: hRPB33,RPB31,hsRPB3,RPB3)

POLR2C biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mitotic cell cycleGO:00073461890.404
regulation of cell cycleGO:00517263930.360
regulation of cell cycle processGO:00105642660.335
carboxylic acid biosynthetic processGO:0046394970.252
negative regulation of cell cycleGO:00457861930.193
small molecule biosynthetic processGO:00442831570.178
mitotic cell cycle phase transitionGO:00447721620.172
negative regulation of cell proliferationGO:00082852280.165
regulation of mitotic cell cycle phase transitionGO:19019901180.156
post embryonic developmentGO:000979120.141
Worm
cell cycle phase transitionGO:00447701730.141
vesicle mediated transportGO:00161923710.138
negative regulation of cell cycle processGO:00109481210.138
female gamete generationGO:000729220.137
regulation of cell cycle phase transitionGO:19019871260.136
cellular macromolecule catabolic processGO:00442653800.129
negative regulation of mitotic cell cycleGO:00459301020.121
mitotic cell cycle processGO:19030472860.117
negative regulation of multicellular organismal processGO:00512413170.111
negative regulation of cell cycle phase transitionGO:1901988890.107
negative regulation of mitotic cell cycle phase transitionGO:1901991850.094
lipid metabolic processGO:00066293810.087
dna integrity checkpointGO:0031570710.086
regulation of cell divisionGO:00513021160.086
negative regulation of cellular component organizationGO:00511292350.080
protein modification by small protein conjugationGO:00324463420.075
protein catabolic processGO:00301633250.074
modification dependent macromolecule catabolic processGO:00436322120.070
cellular protein catabolic processGO:00442572610.065
response to oxygen containing compoundGO:19017003690.063
regulation of locomotionGO:00400123290.059
cellular response to endogenous stimulusGO:00714953360.059
membrane organizationGO:00610242920.059
mitotic cell cycle checkpointGO:0007093680.059
regulation of cellular ketone metabolic processGO:0010565500.056
regulation of cell developmentGO:00602841610.055
mitotic dna damage checkpointGO:0044773280.051
response to other organismGO:00517072610.051
cell cycle checkpointGO:00000751170.051
cellular ketone metabolic processGO:0042180800.051
negative regulation of cell differentiationGO:00455961710.049
rna splicingGO:00083801310.049
lipid biosynthetic processGO:00086101770.049
response to virusGO:00096151260.048
negative regulation of developmental processGO:00510932470.047
positive regulation of cell deathGO:00109422630.046
modification dependent protein catabolic processGO:00199412090.045
g2 dna damage checkpointGO:0031572260.045
regulation of neural precursor cell proliferationGO:200017740.044
cardiac muscle cell contractionGO:008600340.043
cellular response to dna damage stimulusGO:00069743790.043
rna processingGO:00063962550.043
positive regulation of cellular amine metabolic processGO:003324070.042
regulation of cellular component movementGO:00512703340.042
regulation of sequence specific dna binding transcription factor activityGO:00510902110.042
positive regulation of catabolic processGO:00098963100.041
cellular lipid metabolic processGO:00442553030.039
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361950.039
embryo developmentGO:00097901230.039
Worm
organelle fissionGO:00482851490.039
positive regulation of cellular amino acid metabolic processGO:004576430.037
calcium ion transportGO:00068161470.037
regulation of cellular amine metabolic processGO:0033238110.037
positive regulation of apoptotic processGO:00430652460.036
negative regulation of protein metabolic processGO:00512483910.036
proteolysis involved in cellular protein catabolic processGO:00516032440.036
regulation of feeding behaviorGO:006025930.035
establishment or maintenance of apical basal cell polarityGO:003508820.035
mitotic cell cycleGO:00002783260.035
photoreceptor cell differentiationGO:004653020.035
negative regulation of locomotionGO:00400131180.035
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.034
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.034
negative regulation of oxidative stress induced neuron deathGO:190320470.034
regulation of kinase activityGO:00435493140.034
endomembrane system organizationGO:00102561960.033
metal ion transportGO:00300012720.033
regulation of proteolysisGO:00301622930.033
regulation of nuclear divisionGO:0051783650.033
cell developmentGO:00484683280.033
mitotic nuclear divisionGO:00070671190.033
cytoplasmic transportGO:00164823790.032
single organism reproductive processGO:0044702980.032
reproductive structure developmentGO:0048608550.032
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.032
response to lipidGO:00339932060.031
organophosphate catabolic processGO:00464344300.031
single organism membrane organizationGO:00448022680.031
determination of adult lifespanGO:000834020.031
regulation of cytokine productionGO:00018172320.030
cell divisionGO:00513011680.030
positive regulation of cellular component organizationGO:00511303760.029
positive regulation of purine nucleotide catabolic processGO:00331231850.029
actin filament based processGO:00300292240.029
oogenesisGO:004847720.028
positive regulation of transferase activityGO:00513472270.028
regulation of behaviorGO:0050795820.028
response to external biotic stimulusGO:00432072610.028
single organism carbohydrate metabolic processGO:00447231930.027
divalent metal ion transportGO:00708381520.027
negative regulation of oxidative stress induced cell deathGO:1903202170.027
growthGO:00400072020.026
transcription from rna polymerase iii promoterGO:0006383190.026
neuromuscular junction developmentGO:000752830.026
reproductive processGO:00224141060.026
cardiac muscle contractionGO:0060048340.026
chemical homeostasisGO:00488783060.026
protein ubiquitinationGO:00165673140.026
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.026
associative learningGO:000830610.025
positive regulation of cellular protein catabolic processGO:1903364370.025
negative regulation of cell divisionGO:0051782310.025
epithelium developmentGO:00604292270.025
ion transmembrane transportGO:00342203380.025
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:003609130.025
positive regulation of hydrolase activityGO:00513453310.024
nervous system developmentGO:00073992930.024
amine metabolic processGO:0009308440.024
negative regulation of cell migrationGO:00303361020.024
response to biotic stimulusGO:00096072760.024
nucleoside triphosphate catabolic processGO:00091433940.024
maintenance of locationGO:00512351120.024
carbohydrate metabolic processGO:00059752070.024
reproductive system developmentGO:0061458560.024
positive regulation of protein ubiquitinationGO:0031398530.024
regulation of response to oxidative stressGO:1902882260.024
cellular response to lipidGO:00713961270.024
gtp metabolic processGO:00460392390.024
cellular component morphogenesisGO:00329893140.023
proteasomal protein catabolic processGO:00104981760.023
peptidyl glutamic acid modificationGO:001820040.023
ribonucleoside catabolic processGO:00424544060.023
regulation of protein bindingGO:0043393660.023
purine ribonucleoside metabolic processGO:00461284370.023
dna damage checkpointGO:0000077680.023
regulation of multi organism processGO:00439001570.023
regulation of cell motilityGO:20001452990.022
negative regulation of phosphorylationGO:00423261740.022
double strand break repairGO:00063021010.022
negative regulation of catalytic activityGO:00430863350.022
histone arginine methylationGO:003496960.022
leukocyte activationGO:00453211640.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
regulation of lipid biosynthetic processGO:0046890470.021
locomotory behaviorGO:000762610.021
actin mediated cell contractionGO:0070252120.021
regulation of growthGO:00400081650.021
regulation of protein localizationGO:00328802960.021
cellular calcium ion homeostasisGO:00068741170.021
regenerationGO:003109940.021
cellular cation homeostasisGO:00300031630.021
negative regulation of phosphate metabolic processGO:00459362670.021
ribonucleoside triphosphate catabolic processGO:00092033910.020
small gtpase mediated signal transductionGO:0007264780.020
organelle assemblyGO:00709251760.020
immune responseGO:00069553070.020
establishment or maintenance of bipolar cell polarityGO:006124520.020
rna polyadenylationGO:0043631140.020
neuroblast proliferationGO:000740540.020
regulation of protein modification by small protein conjugation or removalGO:19033201070.020
organic acid biosynthetic processGO:0016053970.020
regulation of establishment of protein localizationGO:00702012420.020
cell death in response to oxidative stressGO:0036473290.020
protein maturationGO:00516042330.020
regulation of cellular response to stressGO:00801352440.020
regulation of microtubule based processGO:0032886740.019
cellular amine metabolic processGO:0044106410.019
regulation of nucleotide catabolic processGO:00308112050.019
response to hormoneGO:00097251750.019
single organism cellular localizationGO:19025803320.019
regulation of heart contractionGO:0008016500.019
positive regulation of gtp catabolic processGO:00331261660.019
ubiquitin dependent protein catabolic processGO:00065112060.019
ribonucleotide catabolic processGO:00092614050.018
negative regulation of cell motilityGO:20001461040.018
wnt signaling pathwayGO:00160551560.018
i kappab kinase nf kappab signalingGO:00072491660.018
posttranscriptional regulation of gene expressionGO:00106082130.018
response to unfolded proteinGO:0006986240.018
development of primary sexual characteristicsGO:0045137350.018
cell type specific apoptotic processGO:00972851250.018
regulation of secretionGO:00510461940.018
purine nucleoside triphosphate catabolic processGO:00091463920.018
rhythmic behaviorGO:000762220.018
cellular amino acid metabolic processGO:00065201160.018
regulation of cell differentiationGO:00455953930.018
positive regulation of cellular catabolic processGO:00313312840.018
positive regulation of phosphorylationGO:00423273940.018
regulation of protein serine threonine kinase activityGO:00719001790.018
store operated calcium entryGO:000211530.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
transmembrane transportGO:00550853990.018
positive regulation of nucleotide catabolic processGO:00308131850.018
gtp catabolic processGO:00061842370.018
regulation of cellular amino acid metabolic processGO:000652160.017
purine nucleoside triphosphate metabolic processGO:00091444120.017
purine nucleoside catabolic processGO:00061523980.017
positive regulation of ligase activityGO:0051351190.017
autophagyGO:0006914880.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
regulation of nervous system developmentGO:0051960880.017
rna interferenceGO:001624640.017
purine ribonucleotide catabolic processGO:00091544040.017
negative regulation of response to external stimulusGO:0032102830.017
cellular metal ion homeostasisGO:00068751460.017
monocarboxylic acid biosynthetic processGO:0072330670.017
positive regulation of nucleoside metabolic processGO:00459791860.017
negative regulation of protein modification processGO:00314002000.017
ras protein signal transductionGO:0007265730.016
negative regulation of organelle organizationGO:00106391260.016
regulation of neuroblast proliferationGO:190269230.016
divalent inorganic cation homeostasisGO:00725071360.016
regulation of oxidative stress induced cell deathGO:1903201240.016
ribonucleoprotein complex biogenesisGO:00226131160.016
cell activationGO:00017752130.016
biological adhesionGO:00226103310.016
regulation of meiosisGO:004002030.016
neurotransmitter secretionGO:000726940.015
fatty acid biosynthetic processGO:0006633460.015
intracellular protein transportGO:00068862700.015
t cell differentiation in thymusGO:003307740.015
ribonucleoprotein complex assemblyGO:0022618780.015
regulation of cell migrationGO:00303342890.015
regulation of nucleotide metabolic processGO:00061402690.015
regulation of meiotic cell cycleGO:005144540.015
membrane fusionGO:0061025430.015
regulation of protein kinase activityGO:00458592890.015
intrinsic apoptotic signaling pathwayGO:00971931270.015
rna splicing via transesterification reactionsGO:0000375900.015
system processGO:00030083490.015
divalent inorganic cation transportGO:00725111580.015
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.015
transcription from rna polymerase i promoterGO:0006360110.015
protein oligomerizationGO:00512591730.015
regulation of ras protein signal transductionGO:00465781550.015
purine nucleotide catabolic processGO:00061954050.015
negative regulation of transferase activityGO:00513481240.015
regulation of transferase activityGO:00513383550.014
eye photoreceptor cell differentiationGO:000175420.014
endocytosisGO:00068971590.014
hexose metabolic processGO:0019318550.014
blood vessel maturationGO:000195510.014
sequestering of calcium ionGO:0051208170.014
stress activated mapk cascadeGO:0051403930.014
regulation of innate immune responseGO:0045088970.014
regulation of response to biotic stimulusGO:0002831550.014
guanosine containing compound catabolic processGO:19010692390.014
cilium morphogenesisGO:0060271750.014
response to starvationGO:0042594590.014
purine ribonucleoside triphosphate catabolic processGO:00092073910.014
positive regulation of programmed cell deathGO:00430682490.014
receptor mediated endocytosisGO:0006898840.014
blastocyst developmentGO:000182430.014
positive regulation of protein phosphorylationGO:00019343130.014
protein targetingGO:00066051870.014
chromatin organizationGO:00063253510.014
protein dephosphorylationGO:0006470810.014
striated muscle contractionGO:0006941520.014
dna repairGO:00062811980.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
regulation of purine nucleotide catabolic processGO:00331212050.014
endochondral bone morphogenesisGO:006035030.014
cell adhesionGO:00071553250.014
cellular response to hormone stimulusGO:00328701250.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
positive regulation of bindingGO:0051099450.014
innate immune responseGO:00450871780.014
negative regulation of kinase activityGO:00336731060.013
regulation of neurogenesisGO:0050767820.013
regulation of excretionGO:004406210.013
sex differentiationGO:0007548450.013
nuclear transportGO:00511691790.013
regulation of vesicle mediated transportGO:00606271300.013
negative regulation of transportGO:00510511760.013
nucleoside phosphate catabolic processGO:19012924120.013
regulation of protein transportGO:00512232130.013
purine ribonucleoside catabolic processGO:00461303980.013
engulfment of apoptotic cellGO:004365220.013
leukocyte apoptotic processGO:0071887310.013
defense responseGO:00069523150.013
negative regulation of protein kinase activityGO:0006469980.013
protein localization to organelleGO:00333652800.013
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.013
calcium ion homeostasisGO:00550741220.013
actin filament based movementGO:0030048170.013
cell morphogenesisGO:00009022960.013
secretionGO:00469032540.013
response to abiotic stimulusGO:00096283360.012
Fly
lymphocyte activationGO:00466491330.012
negative regulation of cell deathGO:00605483450.012
positive regulation of nucleotide metabolic processGO:00459812300.012
mrna processingGO:00063971330.012
glucose metabolic processGO:0006006450.012
regulation of viral processGO:00507921030.012
dephosphorylationGO:00163112090.012
nucleoside triphosphate metabolic processGO:00091414220.012
compound eye developmentGO:004874910.012
cartilage development involved in endochondral bone morphogenesisGO:006035120.012
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.012
positive regulation of gtpase activityGO:00435471660.012
regulation of transcription during mitosisGO:004589620.012
regulation of ubiquitin protein transferase activityGO:0051438280.012
negative regulation of proteolysisGO:00458611320.012
regulation of developmental growthGO:0048638300.012
negative regulation of smooth muscle cell migrationGO:001491270.012
nuclear divisionGO:00002801280.012
regulation of immune responseGO:00507762010.012
positive regulation of feeding behaviorGO:200025310.012
cation homeostasisGO:00550801890.012
regulation of intracellular transportGO:00323861950.012
signal transduction by phosphorylationGO:00230142970.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
regulation of muscle contractionGO:0006937450.012
cardiovascular system developmentGO:00723582620.012
gonad developmentGO:0008406340.012
regulation of nucleoside metabolic processGO:00091182090.012
lymphocyte homeostasisGO:000226040.012
positive regulation of cell proliferationGO:00082843010.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
g1 s transition of mitotic cell cycleGO:0000082780.012
negative regulation of phosphorus metabolic processGO:00105632670.012
negative regulation of immune system processGO:00026831360.012
circadian regulation of gene expressionGO:003292280.011
sequestering of metal ionGO:0051238240.011
response to nitrogen compoundGO:19016981840.011
er nucleus signaling pathwayGO:0006984230.011
maintenance of location in cellGO:0051651620.011
secretion by cellGO:00329402260.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
microtubule based processGO:00070172100.011
regulation of membrane potentialGO:0042391950.011
negative regulation of cell developmentGO:0010721480.011
cellular response to organic cyclic compoundGO:00714071270.011
cation transportGO:00068123310.011
response to extracellular stimulusGO:0009991850.011
muscle contractionGO:0006936730.011
response to nutrient levelsGO:0031667810.011
macromolecule methylationGO:0043414970.011
positive regulation of ras gtpase activityGO:00323201170.011
transcription initiation from rna polymerase ii promoterGO:0006367270.011
mrna splicing via spliceosomeGO:0000398890.011
glycosyl compound catabolic processGO:19016584130.011
cellular ion homeostasisGO:00068731680.011
positive regulation of protein catabolic processGO:0045732750.011
dna conformation changeGO:00711031130.011
interspecies interaction between organismsGO:00444191560.011
termination of rna polymerase ii transcriptionGO:000636910.011
Yeast
cellular response to peptide hormone stimulusGO:0071375560.011
nucleotide catabolic processGO:00091664080.011
protein processingGO:00164852260.011
t cell homeostasisGO:004302930.011
regulation of cytoskeleton organizationGO:00514931770.011
negative regulation of cellular protein metabolic processGO:00322693530.011
segmentationGO:003528240.010
developmental process involved in reproductionGO:0003006660.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
negative regulation of multi organism processGO:0043901920.010
plasma membrane organizationGO:00070091150.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
neuron death in response to oxidative stressGO:003647590.010
regulation of actin cytoskeleton organizationGO:00329561160.010
protein alkylationGO:0008213740.010
negative regulation of neural precursor cell proliferationGO:200017810.010
circulatory system processGO:00030131130.010
vesicle organizationGO:0016050620.010
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:0070059120.010
cell projection morphogenesisGO:00488581290.010
mrna metabolic processGO:00160711750.010
regulation of gtpase activityGO:00430871800.010

POLR2C disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.026
nervous system diseaseDOID:8634310.026
eye and adnexa diseaseDOID:14921500.022
retinal degenerationDOID:8466890.020
retinal diseaseDOID:56791180.020
eye diseaseDOID:56141490.020
disease of metabolismDOID:00146672950.016
disease of mental healthDOID:150700.011
retinitis pigmentosaDOID:10584510.011