Homo sapiens

31 known processes

POLR2B

polymerase (RNA) II (DNA directed) polypeptide B, 140kDa

(Aliases: hRPB140,hsRPB2,RPB2,POL2RB)

POLR2B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.801
Worm
regulation of meiotic cell cycleGO:005144540.431
female gamete generationGO:000729220.353
regulation of meiosisGO:004002030.343
nuclear divisionGO:00002801280.336
rna processingGO:00063962550.326
organelle fissionGO:00482851490.261
purine nucleoside monophosphate catabolic processGO:00091281580.247
atp catabolic processGO:00062001570.238
response to biotic stimulusGO:00096072760.226
response to other organismGO:00517072610.217
macromolecule methylationGO:0043414970.205
nucleoside monophosphate metabolic processGO:00091231910.202
response to external biotic stimulusGO:00432072610.201
purine ribonucleoside catabolic processGO:00461303980.186
ribonucleoside monophosphate metabolic processGO:00091611870.180
nucleoside monophosphate catabolic processGO:00091251590.179
regulation of cell cycle processGO:00105642660.172
cell developmentGO:00484683280.169
purine ribonucleoside triphosphate metabolic processGO:00092054110.156
oogenesisGO:004847720.154
atp metabolic processGO:00460341760.152
vesicle mediated transportGO:00161923710.145
cellular macromolecule catabolic processGO:00442653800.144
cell cycle phase transitionGO:00447701730.140
positive regulation of cellular amine metabolic processGO:003324070.137
mrna metabolic processGO:00160711750.133
rna splicingGO:00083801310.129
purine nucleoside monophosphate metabolic processGO:00091261860.122
nucleoside catabolic processGO:00091644080.117
mitotic cell cycle processGO:19030472860.113
purine ribonucleoside triphosphate catabolic processGO:00092073910.112
embryo developmentGO:00097901230.112
Worm
methylationGO:00322591060.107
rna interferenceGO:001624640.107
gene silencingGO:0016458490.103
cellular amine metabolic processGO:0044106410.102
purine ribonucleoside monophosphate catabolic processGO:00091691580.101
single organism reproductive processGO:0044702980.100
Worm
organophosphate catabolic processGO:00464344300.098
ribonucleoside catabolic processGO:00424544060.096
determination of adult lifespanGO:000834020.093
ribonucleotide catabolic processGO:00092614050.091
purine nucleoside triphosphate catabolic processGO:00091463920.090
regulation of cell cycleGO:00517263930.088
mitotic cell cycleGO:00002783260.088
cellular ketone metabolic processGO:0042180800.087
embryo development ending in birth or egg hatchingGO:0009792340.085
Worm
developmental growthGO:0048589480.073
ncrna processingGO:0034470830.070
cell divisionGO:00513011680.069
protein catabolic processGO:00301633250.069
purine ribonucleoside monophosphate metabolic processGO:00091671860.068
mitotic nuclear divisionGO:00070671190.068
regulation of mitotic cell cycle phase transitionGO:19019901180.068
posttranscriptional regulation of gene expressionGO:00106082130.066
endocytosisGO:00068971590.065
cellular response to dna damage stimulusGO:00069743790.064
nucleoside triphosphate catabolic processGO:00091433940.064
negative regulation of cell deathGO:00605483450.062
regulation of cellular amine metabolic processGO:0033238110.062
nucleotide catabolic processGO:00091664080.062
regulation of growthGO:00400081650.061
ribonucleoside monophosphate catabolic processGO:00091581580.061
negative regulation of cell cycle processGO:00109481210.060
defense responseGO:00069523150.059
protein modification by small protein conjugationGO:00324463420.059
posttranscriptional gene silencingGO:0016441250.057
system processGO:00030083490.056
regulation of cellular amino acid metabolic processGO:000652160.055
positive regulation of cellular amino acid metabolic processGO:004576430.054
developmental process involved in reproductionGO:0003006660.054
Worm
embryonic morphogenesisGO:0048598850.053
neurogenesisGO:00220081690.052
negative regulation of apoptotic processGO:00430663160.051
cellular amino acid metabolic processGO:00065201160.051
rna phosphodiester bond hydrolysisGO:0090501350.049
receptor mediated endocytosisGO:0006898840.049
sister chromatid segregationGO:0000819540.048
mrna splicing via spliceosomeGO:0000398890.048
purine ribonucleoside metabolic processGO:00461284370.048
purine containing compound catabolic processGO:00725234110.048
ribonucleoside triphosphate catabolic processGO:00092033910.047
positive regulation of cellular component organizationGO:00511303760.047
nucleic acid phosphodiester bond hydrolysisGO:00903051020.047
purine nucleoside triphosphate metabolic processGO:00091444120.046
glycosyl compound catabolic processGO:19016584130.045
growthGO:00400072020.042
purine nucleotide catabolic processGO:00061954050.042
generation of neuronsGO:00486991520.042
spermatid developmentGO:000728640.041
response to bacteriumGO:00096171440.041
chromatin modificationGO:00165682980.040
protein methylationGO:0006479740.040
reproductive structure developmentGO:0048608550.039
Worm
negative regulation of cellular protein metabolic processGO:00322693530.039
defense response to other organismGO:00985421290.038
ncrna metabolic processGO:00346601080.037
rna 3 end processingGO:0031123350.037
regulation of nuclear divisionGO:0051783650.037
segmentationGO:003528240.036
multicellular organismal agingGO:001025930.036
regulation of developmental growthGO:0048638300.036
immune responseGO:00069553070.035
positive regulation of growthGO:0045927580.035
regulation of cellular ketone metabolic processGO:0010565500.035
negative regulation of cell cycleGO:00457861930.035
dna conformation changeGO:00711031130.034
mitotic cell cycle phase transitionGO:00447721620.033
dna repairGO:00062811980.033
reproductionGO:0000003630.033
Worm
response to organic cyclic compoundGO:00140702040.032
spermatid differentiationGO:004851540.031
cellular macromolecular complex assemblyGO:00346223240.031
nucleoside phosphate catabolic processGO:19012924120.031
purine nucleoside catabolic processGO:00061523980.031
regulation of cellular component biogenesisGO:00440872810.030
cytoplasmic transportGO:00164823790.030
intrinsic apoptotic signaling pathwayGO:00971931270.030
meiotic chromosome segregationGO:004513240.030
apoptotic signaling pathwayGO:00971902680.029
chromatin organizationGO:00063253510.029
regulation of rna splicingGO:0043484620.029
cellular response to organic cyclic compoundGO:00714071270.028
modification dependent macromolecule catabolic processGO:00436322120.028
negative regulation of programmed cell deathGO:00430693210.028
microtubule based processGO:00070172100.027
circulatory system developmentGO:00723592620.027
cellular component morphogenesisGO:00329893140.027
nucleoside triphosphate metabolic processGO:00091414220.027
purine ribonucleotide catabolic processGO:00091544040.026
blastocyst developmentGO:000182430.026
neuron developmentGO:00486661130.026
reproductive processGO:00224141060.025
Worm
rna splicing via transesterification reactionsGO:0000375900.025
multicellular organismal reproductive processGO:0048609400.025
positive regulation of developmental processGO:00510943140.025
establishment or maintenance of cytoskeleton polarityGO:003095230.025
amine metabolic processGO:0009308440.024
cardiovascular system developmentGO:00723582620.024
negative regulation of phosphate metabolic processGO:00459362670.023
innate immune responseGO:00450871780.023
negative regulation of cell cycle phase transitionGO:1901988890.023
intracellular protein transportGO:00068862700.023
mrna processingGO:00063971330.022
cell morphogenesisGO:00009022960.022
chromosome segregationGO:00070591140.022
neuromuscular junction developmentGO:000752830.022
gene silencing by rnaGO:0031047260.021
regulation of dna metabolic processGO:00510521530.021
regulation of cell cycle phase transitionGO:19019871260.021
reproductive system developmentGO:0061458560.021
Worm
protein localization to organelleGO:00333652800.020
mitotic sister chromatid segregationGO:0000070530.020
nervous system developmentGO:00073992930.020
meiotic nuclear divisionGO:0007126100.019
positive regulation of catabolic processGO:00098963100.019
protein ubiquitinationGO:00165673140.019
multicellular organism reproductionGO:0032504420.019
negative regulation of mitotic cell cycle phase transitionGO:1901991850.019
response to radiationGO:00093141510.018
regulation of gene expression epigeneticGO:0040029730.018
mitotic dna replication checkpointGO:003331420.018
signal transduction by p53 class mediatorGO:0072331720.018
negative regulation of cellular component organizationGO:00511292350.018
response to abiotic stimulusGO:00096283360.018
covalent chromatin modificationGO:00165692540.017
positive regulation of cellular component biogenesisGO:00440891580.017
defense response to bacteriumGO:0042742630.017
microtubule cytoskeleton organizationGO:00002261760.017
regulation of cell divisionGO:00513021160.017
development of primary sexual characteristicsGO:0045137350.017
Worm
regulation of protein complex assemblyGO:00432541470.017
negative regulation of phosphorus metabolic processGO:00105632670.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
agingGO:0007568660.017
single organism cellular localizationGO:19025803320.017
dna integrity checkpointGO:0031570710.017
response to growth factorGO:00708482050.016
cellular protein catabolic processGO:00442572610.016
nitrogen compound transportGO:00717051910.016
ribonucleoprotein complex biogenesisGO:00226131160.016
nucleus organizationGO:0006997280.016
modification dependent protein catabolic processGO:00199412090.016
neurological system processGO:00508771630.016
cell type specific apoptotic processGO:00972851250.015
response to lipidGO:00339932060.015
response to nitrogen compoundGO:19016981840.015
multi organism reproductive processGO:0044703540.015
proteasomal protein catabolic processGO:00104981760.015
positive regulation of protein complex assemblyGO:0031334860.015
nucleobase containing compound transportGO:0015931510.015
negative regulation of developmental processGO:00510932470.015
cellular protein complex assemblyGO:00436231880.015
cell morphogenesis involved in differentiationGO:00009041440.015
response to oxygen containing compoundGO:19017003690.015
g2 dna damage checkpointGO:0031572260.013
blood vessel developmentGO:00015681720.013
nucleosome organizationGO:0034728660.013
stem cell differentiationGO:0048863930.013
cellular response to oxygen containing compoundGO:19017012760.013
establishment of protein localization to organelleGO:00725941720.013
meiotic cell cycleGO:0051321130.013
cell projection morphogenesisGO:00488581290.013
transcription initiation from rna polymerase ii promoterGO:0006367270.013
neuron differentiationGO:00301821380.013
lipid metabolic processGO:00066293810.013
histone methylationGO:0016571600.013
protein dna complex subunit organizationGO:0071824800.013
vasculature developmentGO:00019441810.012
cell projection organizationGO:00300302520.012
regulation of immune responseGO:00507762010.012
cellular amide metabolic processGO:0043603690.012
cell cycle checkpointGO:00000751170.012
negative regulation of immune system processGO:00026831360.012
nuclear transcribed mrna catabolic processGO:0000956480.012
regulation of mitotic cell cycleGO:00073461890.012
regionalizationGO:0003002290.012
posttranscriptional gene silencing by rnaGO:0035194250.012
chemotaxisGO:00069351570.012
engulfment of apoptotic cellGO:004365220.012
gonad developmentGO:0008406340.012
Worm
nuclear importGO:00511701060.011
negative regulation of intracellular signal transductionGO:19025321830.011
histone modificationGO:00165702510.011
peptidyl lysine modificationGO:00182051440.011
regulation of chromosome organizationGO:00330441030.011
regulation of chromatin organizationGO:1902275560.011
protein dephosphorylationGO:0006470810.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
sexual reproductionGO:0019953370.011
regulation of multicellular organism growthGO:004001480.011
protein polyubiquitinationGO:00002091100.011
regulation of nervous system developmentGO:0051960880.010
striated muscle contractionGO:0006941520.010
tube developmentGO:00352951250.010
cell growthGO:00160491600.010

POLR2B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.014
central nervous system diseaseDOID:3311860.014
neurodegenerative diseaseDOID:12891020.010