Homo sapiens

31 known processes

POLR2L

polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa

(Aliases: RPB7.6,RPABC5,RBP10,RPB10beta,RPB10,hRPB7.6,hsRPB10b)

POLR2L biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of apoptotic signaling pathwayGO:20012331750.307
cellular lipid metabolic processGO:00442553030.275
membrane organizationGO:00610242920.231
vesicle mediated transportGO:00161923710.226
regulation of cell cycle processGO:00105642660.200
regulation of cell cycleGO:00517263930.174
post embryonic developmentGO:000979120.147
negative regulation of apoptotic processGO:00430663160.145
transcription from rna polymerase iii promoterGO:0006383190.118
Yeast
single organism membrane organizationGO:00448022680.114
lipid metabolic processGO:00066293810.091
oogenesisGO:004847720.089
negative regulation of phosphate metabolic processGO:00459362670.081
positive regulation of transportGO:00510503360.075
positive regulation of reactive oxygen species metabolic processGO:2000379240.072
negative regulation of cellular protein metabolic processGO:00322693530.069
fatty acid metabolic processGO:00066311150.069
negative regulation of cell cycleGO:00457861930.067
reactive oxygen species metabolic processGO:0072593750.063
extrinsic apoptotic signaling pathwayGO:00971911190.062
apoptotic signaling pathwayGO:00971902680.060
positive regulation of cellular component organizationGO:00511303760.060
positive regulation of cell deathGO:00109422630.059
cell developmentGO:00484683280.059
negative regulation of protein metabolic processGO:00512483910.058
negative regulation of catalytic activityGO:00430863350.053
mitotic cell cycleGO:00002783260.053
posttranscriptional regulation of gene expressionGO:00106082130.052
mitochondrial membrane organizationGO:0007006400.051
regulation of peroxidase activityGO:200046820.050
cellular response to dna damage stimulusGO:00069743790.050
single organism cellular localizationGO:19025803320.049
negative regulation of cell deathGO:00605483450.048
protein localization to membraneGO:00726571600.046
regulation of mitotic cell cycle phase transitionGO:19019901180.045
mitochondrion organizationGO:00070051560.044
endocytosisGO:00068971590.044
intracellular protein transportGO:00068862700.043
negative regulation of programmed cell deathGO:00430693210.043
mapk cascadeGO:00001652880.042
cytoplasmic transportGO:00164823790.041
regulation of endopeptidase activityGO:00525481700.041
photoreceptor cell differentiationGO:004653020.040
positive regulation of cell proliferationGO:00082843010.039
negative regulation of phosphorylationGO:00423261740.038
immune responseGO:00069553070.037
female gamete generationGO:000729220.037
mitotic cell cycle processGO:19030472860.037
regulation of mitotic cell cycleGO:00073461890.035
regulation of growthGO:00400081650.035
negative regulation of apoptotic signaling pathwayGO:2001234970.034
cellular amine metabolic processGO:0044106410.033
neurogenesisGO:00220081690.032
oxidation reduction processGO:00551143960.032
negative regulation of mitotic cell cycleGO:00459301020.032
regulation of kinase activityGO:00435493140.031
positive regulation of nucleotide metabolic processGO:00459812300.031
mitotic cell cycle phase transitionGO:00447721620.031
cellular ketone metabolic processGO:0042180800.030
negative regulation of cell proliferationGO:00082852280.030
rna interferenceGO:001624640.030
regulation of peptidase activityGO:00525471800.030
interleukin 1 beta productionGO:0032611220.030
intrinsic apoptotic signaling pathwayGO:00971931270.030
positive regulation of hydrolase activityGO:00513453310.029
regulation of protein localizationGO:00328802960.029
positive regulation of purine nucleotide metabolic processGO:19005442270.029
regulation of map kinase activityGO:00434051080.028
regulation of cell divisionGO:00513021160.028
negative regulation of intracellular signal transductionGO:19025321830.027
response to oxygen containing compoundGO:19017003690.027
response to lipidGO:00339932060.026
cellular response to oxygen containing compoundGO:19017012760.026
regulation of cell growthGO:00015581350.026
cell divisionGO:00513011680.026
cell cycle phase transitionGO:00447701730.026
organelle assemblyGO:00709251760.026
establishment of protein localization to organelleGO:00725941720.025
regulation of protein serine threonine kinase activityGO:00719001790.025
cellular response to lipidGO:00713961270.025
cellular component morphogenesisGO:00329893140.025
reproductionGO:0000003630.025
organelle fissionGO:00482851490.025
positive regulation of apoptotic processGO:00430652460.024
negative regulation of phosphorus metabolic processGO:00105632670.024
positive regulation of programmed cell deathGO:00430682490.023
amine metabolic processGO:0009308440.023
negative regulation of hydrolase activityGO:00513461820.023
regulation of protein catabolic processGO:00421761550.022
regulation of proteolysisGO:00301622930.022
positive regulation of apoptotic signaling pathwayGO:2001235700.022
regulation of response to external stimulusGO:00321012220.022
regulation of transferase activityGO:00513383550.022
transmembrane transportGO:00550853990.022
small molecule biosynthetic processGO:00442831570.022
positive regulation of cellular amine metabolic processGO:003324070.022
establishment of protein localization to membraneGO:00901501210.022
regulation of cell motilityGO:20001452990.021
defense responseGO:00069523150.021
negative regulation of protein serine threonine kinase activityGO:0071901570.020
defense response to other organismGO:00985421290.020
positive regulation of developmental processGO:00510943140.020
monocarboxylic acid metabolic processGO:00327871850.019
spermatid differentiationGO:004851540.019
negative regulation of cell cycle phase transitionGO:1901988890.019
regulation of leukocyte activationGO:00026941150.019
hematopoietic or lymphoid organ developmentGO:00485341860.018
regulation of protein stabilityGO:0031647870.018
nucleoside phosphate catabolic processGO:19012924120.018
response to radiationGO:00093141510.018
secretion by cellGO:00329402260.018
regulation of mapk cascadeGO:00434082620.018
regulation of anatomical structure morphogenesisGO:00226032860.018
carbohydrate derivative biosynthetic processGO:19011372070.018
protein localization to organelleGO:00333652800.017
ribonucleoside catabolic processGO:00424544060.017
negative regulation of protein phosphorylationGO:00019331400.017
regulation of intracellular transportGO:00323861950.017
response to bacteriumGO:00096171440.017
cell cycle checkpointGO:00000751170.017
regulation of mitochondrion organizationGO:0010821540.017
response to reactive oxygen speciesGO:0000302610.017
cellular response to external stimulusGO:00714961110.016
glycerophospholipid metabolic processGO:0006650840.016
replicative cell agingGO:000130230.016
cell growthGO:00160491600.016
regulation of response to woundingGO:19030341010.016
apoptotic mitochondrial changesGO:0008637570.016
intracellular protein transmembrane importGO:0044743230.016
response to light stimulusGO:0009416870.016
actin filament based processGO:00300292240.016
protein importGO:00170381300.015
cellular protein catabolic processGO:00442572610.015
protein targetingGO:00066051870.015
phospholipid metabolic processGO:0006644990.015
negative regulation of kinase activityGO:00336731060.015
response to uvGO:0009411730.015
purine ribonucleoside metabolic processGO:00461284370.015
nuclear divisionGO:00002801280.015
cellular macromolecule catabolic processGO:00442653800.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
negative regulation of transferase activityGO:00513481240.015
cellular amino acid metabolic processGO:00065201160.015
nervous system developmentGO:00073992930.014
nucleoside catabolic processGO:00091644080.014
response to acid chemicalGO:0001101660.014
cell activationGO:00017752130.014
glycosyl compound catabolic processGO:19016584130.014
leukocyte proliferationGO:0070661740.014
tumor necrosis factor superfamily cytokine productionGO:0071706450.014
regulation of immune responseGO:00507762010.014
innate immune responseGO:00450871780.014
cellular amide metabolic processGO:0043603690.014
single organism reproductive processGO:0044702980.014
positive regulation of organelle organizationGO:00106381950.014
negative regulation of cell cycle processGO:00109481210.014
carboxylic acid biosynthetic processGO:0046394970.014
embryo development ending in birth or egg hatchingGO:0009792340.014
Worm
inner mitochondrial membrane organizationGO:000700780.014
negative regulation of protein modification processGO:00314002000.014
regulation of protein kinase activityGO:00458592890.013
dna replicationGO:00062601160.013
positive regulation of cellular component movementGO:00512721810.013
response to abiotic stimulusGO:00096283360.013
negative regulation of growthGO:0045926970.013
cytokine productionGO:00018162470.013
response to other organismGO:00517072610.013
negative regulation of proteolysisGO:00458611320.013
purine nucleoside catabolic processGO:00061523980.013
regulation of gene expression epigeneticGO:0040029730.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
glutathione metabolic processGO:0006749200.013
cellular response to glucocorticoid stimulusGO:007138540.013
regulation of protein transportGO:00512232130.013
response to external biotic stimulusGO:00432072610.013
regulation of establishment of protein localizationGO:00702012420.013
proteasomal protein catabolic processGO:00104981760.013
regulation of jnk cascadeGO:0046328730.013
positive regulation of proteolysisGO:00458621420.013
release of cytochrome c from mitochondriaGO:0001836350.013
negative regulation of immune system processGO:00026831360.013
regulation of oxidoreductase activityGO:0051341430.013
response to mercury ionGO:004668940.013
fatty acid derivative metabolic processGO:1901568350.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.012
oocyte developmentGO:004859910.012
reproductive processGO:00224141060.012
regulation of intracellular protein transportGO:00331571230.012
cell part morphogenesisGO:00329901370.012
regulation of cytokine productionGO:00018172320.012
regulation of lymphocyte activationGO:00512491030.012
regulation of locomotionGO:00400123290.012
stress activated protein kinase signaling cascadeGO:0031098940.012
cell agingGO:0007569520.012
endomembrane system organizationGO:00102561960.012
unsaturated fatty acid metabolic processGO:0033559370.012
positive regulation of cellular catabolic processGO:00313312840.012
actin cytoskeleton organizationGO:00300362070.012
regulation of meiotic cell cycleGO:005144540.012
erk1 and erk2 cascadeGO:00703711040.012
regulation of protein processingGO:00706131500.012
positive regulation of protein phosphorylationGO:00019343130.011
negative regulation of monocyte chemotactic protein 1 productionGO:007163830.011
cellular modified amino acid metabolic processGO:0006575640.011
negative regulation of multicellular organismal processGO:00512413170.011
regulation of protein maturationGO:19033171500.011
growthGO:00400072020.011
cellular response to growth factor stimulusGO:00713631970.011
cell type specific apoptotic processGO:00972851250.011
negative regulation of mapk cascadeGO:0043409560.011
nuclear transportGO:00511691790.011
negative regulation of cellular component organizationGO:00511292350.011
response to hormoneGO:00097251750.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.011
regulation of erk1 and erk2 cascadeGO:0070372990.011
response to biotic stimulusGO:00096072760.011
cellular response to endogenous stimulusGO:00714953360.011
regulation of cell cycle phase transitionGO:19019871260.010
plasma membrane organizationGO:00070091150.010
protein localization to mitochondrionGO:0070585250.010
response to nitrogen compoundGO:19016981840.010
negative regulation of erk1 and erk2 cascadeGO:0070373140.010
negative regulation of catabolic processGO:00098951040.010
chromosome segregationGO:00070591140.010
purine ribonucleoside catabolic processGO:00461303980.010
cellular response to nitrogen compoundGO:19016991440.010
negative regulation of cell growthGO:0030308830.010

POLR2L disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.028
disease of cellular proliferationDOID:145661740.028
organ system cancerDOID:00506861640.024
endocrine gland cancerDOID:170260.014