Homo sapiens

101 known processes

GTF2H4

general transcription factor IIH, polypeptide 4, 52kDa

(Aliases: TFIIH,TFB2)

GTF2H4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743790.146
Yeast
post embryonic developmentGO:000979120.144
dna repairGO:00062811980.092
Yeast
nucleoside catabolic processGO:00091644080.091
nervous system developmentGO:00073992930.085
regulation of dna metabolic processGO:00510521530.080
determination of adult lifespanGO:000834020.074
multicellular organismal agingGO:001025930.071
nucleic acid phosphodiester bond hydrolysisGO:00903051020.070
purine nucleoside triphosphate catabolic processGO:00091463920.068
vesicle mediated transportGO:00161923710.067
purine nucleoside triphosphate metabolic processGO:00091444120.065
purine nucleoside catabolic processGO:00061523980.064
purine ribonucleotide catabolic processGO:00091544040.063
cellular amino acid metabolic processGO:00065201160.061
purine ribonucleoside metabolic processGO:00461284370.059
purine nucleotide catabolic processGO:00061954050.059
nucleoside triphosphate metabolic processGO:00091414220.057
ribonucleoside triphosphate metabolic processGO:00091994120.056
nucleotide excision repair dna incisionGO:003368370.056
nucleotide catabolic processGO:00091664080.055
purine ribonucleoside triphosphate metabolic processGO:00092054110.053
regulation of cell cycleGO:00517263930.053
nucleoside triphosphate catabolic processGO:00091433940.050
nucleoside phosphate catabolic processGO:19012924120.049
atp metabolic processGO:00460341760.049
purine containing compound catabolic processGO:00725234110.048
ribonucleoside catabolic processGO:00424544060.048
regulation of cellular ketone metabolic processGO:0010565500.048
ribonucleotide catabolic processGO:00092614050.047
purine ribonucleoside triphosphate catabolic processGO:00092073910.046
cellular ketone metabolic processGO:0042180800.045
neurogenesisGO:00220081690.044
cellular macromolecular complex assemblyGO:00346223240.041
positive regulation of cell deathGO:00109422630.041
purine ribonucleoside catabolic processGO:00461303980.040
regulation of cellular amino acid metabolic processGO:000652160.040
cellular amine metabolic processGO:0044106410.040
regulation of cell cycle processGO:00105642660.039
ribonucleoside triphosphate catabolic processGO:00092033910.039
rna processingGO:00063962550.038
organophosphate catabolic processGO:00464344300.037
positive regulation of programmed cell deathGO:00430682490.037
amine metabolic processGO:0009308440.037
cellular macromolecule catabolic processGO:00442653800.036
glycosyl compound catabolic processGO:19016584130.036
cytoplasmic transportGO:00164823790.035
rna splicingGO:00083801310.035
regulation of mitotic cell cycleGO:00073461890.035
ribonucleoside monophosphate catabolic processGO:00091581580.034
response to abiotic stimulusGO:00096283360.033
ribonucleoprotein complex biogenesisGO:00226131160.032
regulation of cellular amine metabolic processGO:0033238110.032
mitotic cell cycle processGO:19030472860.032
endocytosisGO:00068971590.032
negative regulation of cell cycleGO:00457861930.031
mitochondrion organizationGO:00070051560.031
protein processingGO:00164852260.030
chromatin organizationGO:00063253510.030
negative regulation of cellular protein metabolic processGO:00322693530.030
positive regulation of apoptotic processGO:00430652460.029
regulation of transferase activityGO:00513383550.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
mrna metabolic processGO:00160711750.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of developmental processGO:00510943140.028
purine nucleoside monophosphate metabolic processGO:00091261860.028
nucleoside monophosphate metabolic processGO:00091231910.027
neuron differentiationGO:00301821380.027
immune responseGO:00069553070.027
cellular protein complex assemblyGO:00436231880.027
posttranscriptional regulation of gene expressionGO:00106082130.026
female gamete generationGO:000729220.026
embryo developmentGO:00097901230.026
purine ribonucleoside monophosphate metabolic processGO:00091671860.026
purine nucleoside monophosphate catabolic processGO:00091281580.026
mitotic cell cycle phase transitionGO:00447721620.026
nucleotide excision repairGO:0006289310.025
Yeast
gtp catabolic processGO:00061842370.025
protein dna complex subunit organizationGO:0071824800.025
response to uvGO:0009411730.025
defense responseGO:00069523150.025
nucleoside monophosphate catabolic processGO:00091251590.025
cell cycle phase transitionGO:00447701730.025
lipid metabolic processGO:00066293810.025
negative regulation of catalytic activityGO:00430863350.024
regulation of cellular response to stressGO:00801352440.024
negative regulation of programmed cell deathGO:00430693210.024
protein maturationGO:00516042330.024
response to other organismGO:00517072610.024
hair cell differentiationGO:003531520.024
negative regulation of cellular amine metabolic processGO:003323930.024
locomotory behaviorGO:000762610.023
positive regulation of hydrolase activityGO:00513453310.023
generation of neuronsGO:00486991520.023
atp catabolic processGO:00062001570.023
cell projection organizationGO:00300302520.023
endomembrane system organizationGO:00102561960.023
positive regulation of cellular component organizationGO:00511303760.023
response to oxidative stressGO:00069791210.023
ion homeostasisGO:00508012300.022
single organism membrane organizationGO:00448022680.022
response to radiationGO:00093141510.022
phosphorylation of rna polymerase ii c terminal domainGO:007081630.022
Yeast
mitotic cell cycleGO:00002783260.022
response to virusGO:00096151260.022
chemical homeostasisGO:00488783060.022
negative regulation of cell proliferationGO:00082852280.021
regulation of cell differentiationGO:00455953930.021
negative regulation of cell cycle processGO:00109481210.021
response to oxygen containing compoundGO:19017003690.021
regulation of protein kinase activityGO:00458592890.021
cell divisionGO:00513011680.020
nucleobase containing compound transportGO:0015931510.020
positive regulation of cellular catabolic processGO:00313312840.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
interspecies interaction between organismsGO:00444191560.020
apoptotic signaling pathwayGO:00971902680.020
gtp metabolic processGO:00460392390.020
response to external biotic stimulusGO:00432072610.020
regulation of kinase activityGO:00435493140.020
cellular homeostasisGO:00197251960.020
positive regulation of catabolic processGO:00098963100.019
dna templated transcription initiationGO:0006352350.019
growthGO:00400072020.019
signal transduction by phosphorylationGO:00230142970.019
symbiosis encompassing mutualism through parasitismGO:00444031560.019
positive regulation of cellular amine metabolic processGO:003324070.019
negative regulation of phosphorus metabolic processGO:00105632670.019
oxidation reduction processGO:00551143960.019
mrna processingGO:00063971330.019
histone modificationGO:00165702510.019
negative regulation of intracellular signal transductionGO:19025321830.019
ras protein signal transductionGO:0007265730.018
regulation of protein localizationGO:00328802960.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
guanosine containing compound catabolic processGO:19010692390.018
regulation of nucleoside metabolic processGO:00091182090.018
negative regulation of apoptotic processGO:00430663160.018
compound eye developmentGO:004874910.018
regulation of cell cycle phase transitionGO:19019871260.018
receptor mediated endocytosisGO:0006898840.018
ion transmembrane transportGO:00342203380.018
developmental programmed cell deathGO:001062330.018
cell morphogenesisGO:00009022960.017
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.017
response to biotic stimulusGO:00096072760.017
epithelium developmentGO:00604292270.017
regenerationGO:003109940.017
divalent metal ion transportGO:00708381520.017
positive regulation of immune system processGO:00026842830.017
positive regulation of transportGO:00510503360.017
circulatory system developmentGO:00723592620.017
eye photoreceptor cell differentiationGO:000175420.017
oogenesisGO:004847720.017
negative regulation of phosphate metabolic processGO:00459362670.017
cellular lipid metabolic processGO:00442553030.017
small gtpase mediated signal transductionGO:0007264780.017
multi organism cellular processGO:00447641560.017
protein ubiquitinationGO:00165673140.016
anterior posterior axis specificationGO:000994820.016
viral processGO:00160321460.016
system processGO:00030083490.016
cellular component morphogenesisGO:00329893140.016
epithelial cell differentiationGO:00308551410.016
guanosine containing compound metabolic processGO:19010682440.016
membrane organizationGO:00610242920.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
thymus developmentGO:004853830.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
response to light stimulusGO:0009416870.016
negative regulation of protein modification processGO:00314002000.016
protein catabolic processGO:00301633250.016
photoreceptor cell differentiationGO:004653020.016
regulation of purine nucleotide metabolic processGO:19005422640.016
regulation of cell developmentGO:00602841610.016
regulation of peptidase activityGO:00525471800.016
protein localization to organelleGO:00333652800.016
rho protein signal transductionGO:0007266260.015
lipid biosynthetic processGO:00086101770.015
chromatin modificationGO:00165682980.015
central nervous system developmentGO:00074171230.015
regulation of immune responseGO:00507762010.015
carbohydrate derivative biosynthetic processGO:19011372070.015
transmembrane transportGO:00550853990.015
regulation of mapk cascadeGO:00434082620.015
negative regulation of developmental processGO:00510932470.015
response to cytokineGO:00340972320.015
regulation of proteolysisGO:00301622930.015
regulation of cellular component biogenesisGO:00440872810.015
metal ion transportGO:00300012720.015
cellular metal ion homeostasisGO:00068751460.015
cellular component disassemblyGO:0022411920.015
regulation of growthGO:00400081650.015
mrna splicing via spliceosomeGO:0000398890.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of cell growthGO:00015581350.014
protein modification by small protein removalGO:0070646920.014
ribonucleoprotein complex assemblyGO:0022618780.014
biological adhesionGO:00226103310.014
proteasomal protein catabolic processGO:00104981760.014
neuromuscular junction developmentGO:000752830.014
dna recombinationGO:0006310770.014
single organism cellular localizationGO:19025803320.014
innate immune responseGO:00450871780.014
positive regulation of phosphorylationGO:00423273940.014
regulation of multi organism processGO:00439001570.014
nucleocytoplasmic transportGO:00069131760.014
intracellular protein transportGO:00068862700.014
nuclear exportGO:0051168690.014
cardiovascular system developmentGO:00723582620.014
negative regulation of transferase activityGO:00513481240.014
viral life cycleGO:00190581320.014
meiotic chromosome segregationGO:004513240.014
regulation of response to external stimulusGO:00321012220.014
hindbrain developmentGO:003090230.014
neuron developmentGO:00486661130.014
spermatid differentiationGO:004851540.014
cell developmentGO:00484683280.014
regulation of establishment of protein localizationGO:00702012420.014
positive regulation of cell differentiationGO:00455972110.014
double strand break repairGO:00063021010.014
rna splicing via transesterification reactionsGO:0000375900.014
response to oxygen levelsGO:00704821000.013
blastocyst developmentGO:000182430.013
covalent chromatin modificationGO:00165692540.013
negative regulation of cell deathGO:00605483450.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
cell part morphogenesisGO:00329901370.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
negative regulation of phosphorylationGO:00423261740.013
maintenance of locationGO:00512351120.013
nitrogen compound transportGO:00717051910.013
regulation of cytoskeleton organizationGO:00514931770.013
regulation of protein stabilityGO:0031647870.013
cell projection morphogenesisGO:00488581290.013
response to growth factorGO:00708482050.013
cellular protein catabolic processGO:00442572610.013
positive regulation of peptidase activityGO:0010952880.013
protein modification by small protein conjugationGO:00324463420.013
negative regulation of multicellular organismal processGO:00512413170.013
adult locomotory behaviorGO:000834410.013
cell adhesionGO:00071553250.013
segmentationGO:003528240.013
immune system developmentGO:00025201950.013
carbohydrate metabolic processGO:00059752070.013
nuclear transportGO:00511691790.013
cation homeostasisGO:00550801890.013
regulation of meiotic cell cycleGO:005144540.013
dna damage checkpointGO:0000077680.013
base excision repairGO:0006284210.012
regulation of meiosisGO:004002030.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
establishment of rna localizationGO:0051236390.012
positive regulation of nucleotide metabolic processGO:00459812300.012
ribonucleoprotein complex subunit organizationGO:0071826810.012
positive regulation of proteolysisGO:00458621420.012
cellular chemical homeostasisGO:00550821800.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
regulation of nucleotide catabolic processGO:00308112050.012
cellular response to abiotic stimulusGO:00712141170.012
cation transportGO:00068123310.012
chromosome segregationGO:00070591140.012
positive regulation of organelle organizationGO:00106381950.012
cellular response to growth factor stimulusGO:00713631970.012
negative regulation of protein phosphorylationGO:00019331400.012
metencephalon developmentGO:002203720.012
response to lipidGO:00339932060.012
response to decreased oxygen levelsGO:0036293960.012
single organism reproductive processGO:0044702980.012
response to hypoxiaGO:0001666960.012
positive regulation of gtp catabolic processGO:00331261660.012
regulation of endopeptidase activityGO:00525481700.012
cellular response to cytokine stimulusGO:00713451810.012
calcium ion homeostasisGO:00550741220.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
reproductive processGO:00224141060.012
cellular response to oxygen containing compoundGO:19017012760.011
regulation of viral processGO:00507921030.011
oocyte developmentGO:004859910.011
positive regulation of nucleotide catabolic processGO:00308131850.011
negative regulation of protein kinase activityGO:0006469980.011
cellular ion homeostasisGO:00068731680.011
microtubule based processGO:00070172100.011
negative regulation of kinase activityGO:00336731060.011
positive regulation of protein complex assemblyGO:0031334860.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
positive regulation of cellular component biogenesisGO:00440891580.011
single organism carbohydrate metabolic processGO:00447231930.011
regulation of intracellular transportGO:00323861950.011
organelle assemblyGO:00709251760.011
astrocyte differentiationGO:004870840.011
divalent inorganic cation transportGO:00725111580.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
mammary gland morphogenesisGO:006044320.011
oocyte differentiationGO:000999420.011
regulation of locomotionGO:00400123290.011
blastoderm segmentationGO:000735020.011
cell activationGO:00017752130.011
skin developmentGO:0043588760.011
positive regulation of dna metabolic processGO:0051054730.011
regulation of homeostatic processGO:00328441210.011
regulation of anatomical structure morphogenesisGO:00226032860.011
negative regulation of cellular component organizationGO:00511292350.011
dephosphorylationGO:00163112090.011
positive regulation of nucleoside metabolic processGO:00459791860.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
regulation of nucleotide metabolic processGO:00061402690.011
regulation of gtpase activityGO:00430871800.011
leukocyte activationGO:00453211640.011
organelle fissionGO:00482851490.011
actin filament based processGO:00300292240.011
immune effector processGO:00022521590.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
regulation of cell divisionGO:00513021160.011
cell cycle checkpointGO:00000751170.011
translationGO:00064121320.011
neuron projection developmentGO:00311751060.011
reproductive system developmentGO:0061458560.011
associative learningGO:000830610.011
positive regulation of endopeptidase activityGO:0010950840.011
positive regulation of cell proliferationGO:00082843010.010
glycerolipid metabolic processGO:00464861070.010
positive regulation of immune responseGO:00507781590.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
inorganic ion transmembrane transportGO:00986602310.010
establishment of protein localization to organelleGO:00725941720.010
metal ion homeostasisGO:00550651690.010
regulation of response to dna damage stimulusGO:2001020940.010
regulation of ras gtpase activityGO:00323181280.010
cytokine productionGO:00018162470.010
epidermal cell differentiationGO:0009913450.010
regulation of gtp catabolic processGO:00331241800.010
secretion by cellGO:00329402260.010
regulation of mrna metabolic processGO:1903311530.010
response to inorganic substanceGO:00100351270.010
response to organic cyclic compoundGO:00140702040.010
transcription initiation from rna polymerase ii promoterGO:0006367270.010
dna catabolic processGO:0006308490.010
organophosphate biosynthetic processGO:00904071630.010

GTF2H4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.041
cancerDOID:1621670.041
organ system cancerDOID:00506861640.036
disease of metabolismDOID:00146672950.031
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.027
central nervous system diseaseDOID:3311860.026
eye and adnexa diseaseDOID:14921500.024
eye diseaseDOID:56141490.024
retinal degenerationDOID:8466890.024
retinal diseaseDOID:56791180.024
musculoskeletal system diseaseDOID:172230.023
neurodegenerative diseaseDOID:12891020.018
inherited metabolic disorderDOID:6552420.015
gastrointestinal system cancerDOID:3119520.014
xeroderma pigmentosumDOID:005042780.011