Homo sapiens

137 known processes

SUMO1

SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)

(Aliases: OFC10,UBL1,SMT3C,SENP2,PIC1,SMT3,DAP1,SMT3H3,GMP1)

SUMO1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein sumoylationGO:0016925251.000
chromatin organizationGO:00063253510.999
chromatin modificationGO:00165682980.998
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.997
Worm
dna conformation changeGO:00711031130.991
dna packagingGO:0006323770.989
cellular response to dna damage stimulusGO:00069743790.987
histone modificationGO:00165702510.987
protein modification by small protein conjugationGO:00324463420.981
post embryonic developmentGO:000979120.977
Worm
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.960
gene silencingGO:0016458490.960
chromatin assembly or disassemblyGO:0006333780.952
positive regulation of apoptotic processGO:00430652460.948
mitotic cell cycle processGO:19030472860.947
regulation of proteolysisGO:00301622930.945
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.913
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.909
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.893
embryo developmentGO:00097901230.886
Zebrafish Worm
activation of cysteine type endopeptidase activityGO:0097202570.873
chromosome segregationGO:00070591140.855
covalent chromatin modificationGO:00165692540.842
positive regulation of proteolysisGO:00458621420.834
positive regulation of cell deathGO:00109422630.823
response to abiotic stimulusGO:00096283360.789
positive regulation of programmed cell deathGO:00430682490.776
multicellular organismal agingGO:001025930.771
regulation of sequence specific dna binding transcription factor activityGO:00510902110.766
pharynx developmentGO:006046510.760
regulation of protein modification by small protein conjugation or removalGO:19033201070.755
protein ubiquitinationGO:00165673140.755
macromolecule methylationGO:0043414970.753
protein alkylationGO:0008213740.732
histone methylationGO:0016571600.710
determination of adult lifespanGO:000834020.709
cell developmentGO:00484683280.685
mitotic cell cycleGO:00002783260.679
positive regulation of protein sumoylationGO:003323570.673
modification dependent macromolecule catabolic processGO:00436322120.668
regulation of endopeptidase activityGO:00525481700.652
neuron projection developmentGO:00311751060.644
regionalizationGO:0003002290.638
generation of precursor metabolites and energyGO:0006091680.621
viral life cycleGO:00190581320.618
nervous system developmentGO:00073992930.609
regulation of peptidase activityGO:00525471800.575
viral gene expressionGO:0019080350.553
proteolysis involved in cellular protein catabolic processGO:00516032440.553
meiotic chromosome segregationGO:004513240.552
cell projection organizationGO:00300302520.550
regulation of cellular component biogenesisGO:00440872810.531
nucleocytoplasmic transportGO:00069131760.524
positive regulation of catabolic processGO:00098963100.506
microtubule cytoskeleton organizationGO:00002261760.505
positive regulation of apoptotic signaling pathwayGO:2001235700.493
locomotory behaviorGO:000762610.469
modification dependent protein catabolic processGO:00199412090.456
regulation of establishment of protein localizationGO:00702012420.440
interspecies interaction between organismsGO:00444191560.437
protein catabolic processGO:00301633250.433
neuron developmentGO:00486661130.428
positive regulation of protein phosphorylationGO:00019343130.416
negative regulation of protein metabolic processGO:00512483910.414
negative regulation of cellular protein metabolic processGO:00322693530.409
positive regulation of protein catabolic processGO:0045732750.408
response to hypoxiaGO:0001666960.406
viral processGO:00160321460.401
chromatin assemblyGO:0031497610.387
regulation of proteasomal protein catabolic processGO:0061136870.385
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.385
regulation of kinase activityGO:00435493140.382
positive regulation of cysteine type endopeptidase activityGO:2001056790.380
cellular response to endogenous stimulusGO:00714953360.379
multi organism cellular processGO:00447641560.376
cell projection morphogenesisGO:00488581290.375
apoptotic signaling pathwayGO:00971902680.370
embryo development ending in birth or egg hatchingGO:0009792340.370
Worm
neurogenesisGO:00220081690.366
multi organism metabolic processGO:0044033410.366
cell type specific apoptotic processGO:00972851250.361
protein methylationGO:0006479740.348
cellular macromolecule catabolic processGO:00442653800.331
regulation of protein serine threonine kinase activityGO:00719001790.319
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.310
positive regulation of cellular protein catabolic processGO:1903364370.309
zymogen activationGO:0031638700.302
double strand break repairGO:00063021010.298
retina layer formationGO:001084230.298
response to transforming growth factor betaGO:0071559940.293
intracellular protein transportGO:00068862700.291
regulation of transferase activityGO:00513383550.284
protein localization to organelleGO:00333652800.276
Mouse Worm
mitotic spindle organizationGO:0007052270.266
positive regulation of phosphorylationGO:00423273940.251
response to oxygen containing compoundGO:19017003690.246
behaviorGO:00076101120.241
nuclear transportGO:00511691790.238
intracellular receptor signaling pathwayGO:00305221040.235
generation of neuronsGO:00486991520.234
mitotic cell cycle phase transitionGO:00447721620.230
microtubule based processGO:00070172100.228
protein processingGO:00164852260.225
regulation of viral transcriptionGO:0046782340.221
regulation of protein sumoylationGO:0033233130.217
chromatin remodelingGO:0006338550.216
positive regulation of proteasomal protein catabolic processGO:1901800350.213
regulation of cell developmentGO:00602841610.208
dna repairGO:00062811980.198
neuron apoptotic processGO:0051402390.183
response to decreased oxygen levelsGO:0036293960.180
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.180
histone lysine methylationGO:0034968500.180
ras protein signal transductionGO:0007265730.175
cellular response to transforming growth factor beta stimulusGO:0071560940.174
signal transduction by p53 class mediatorGO:0072331720.171
negative regulation of gene expression epigeneticGO:0045814190.167
cytoplasmic transportGO:00164823790.167
oocyte differentiationGO:000999420.167
regulation of cell differentiationGO:00455953930.166
regulation of neuron deathGO:1901214560.166
regulation of dna bindingGO:0051101370.164
negative regulation of catalytic activityGO:00430863350.163
positive regulation of mitotic cell cycle spindle assembly checkpointGO:009026760.161
vesicle mediated transportGO:00161923710.160
regulation of cysteine type endopeptidase activityGO:20001161270.160
regulation of protein catabolic processGO:00421761550.158
positive regulation of cellular catabolic processGO:00313312840.155
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.154
muscle organ developmentGO:0007517560.154
oocyte developmentGO:004859910.153
development of primary sexual characteristicsGO:0045137350.152
Worm
positive regulation of cellular component organizationGO:00511303760.151
oogenesisGO:004847720.149
meiotic nuclear divisionGO:0007126100.149
nuclear importGO:00511701060.148
spermatid developmentGO:000728640.148
posttranscriptional regulation of gene expressionGO:00106082130.147
Mouse
regulation of neuron apoptotic processGO:0043523350.142
negative regulation of bindingGO:0051100570.135
ribonucleoside monophosphate metabolic processGO:00091611870.134
Mouse
carbohydrate biosynthetic processGO:0016051420.134
response to oxidative stressGO:00069791210.133
cellular amine metabolic processGO:0044106410.133
regulation of mitotic cell cycle phase transitionGO:19019901180.132
female gamete generationGO:000729220.131
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.130
single organism nuclear importGO:19025931040.128
cellular carbohydrate metabolic processGO:0044262840.126
regulation of nucleocytoplasmic transportGO:0046822980.124
energy derivation by oxidation of organic compoundsGO:0015980430.122
regulation of viral processGO:00507921030.120
negative regulation of protein ubiquitinationGO:0031397350.118
segmentationGO:003528240.112
positive regulation of peptidase activityGO:0010952880.111
nucleoside phosphate catabolic processGO:19012924120.110
Mouse
central nervous system neuron axonogenesisGO:002195530.109
nuclear divisionGO:00002801280.109
small gtpase mediated signal transductionGO:0007264780.108
neuron projection morphogenesisGO:0048812500.108
dendritic spine morphogenesisGO:006099730.106
androgen receptor signaling pathwayGO:0030521340.106
regulation of cell cycleGO:00517263930.104
neuron differentiationGO:00301821380.103
ameboidal type cell migrationGO:00016671350.102
protein deacetylationGO:0006476380.102
nitrogen compound transportGO:00717051910.100
single organism carbohydrate metabolic processGO:00447231930.100
gonad developmentGO:0008406340.100
Worm
mitotic nuclear divisionGO:00070671190.099
response to oxygen levelsGO:00704821000.099
response to growth factorGO:00708482050.098
circadian behaviorGO:004851220.098
cell cycle phase transitionGO:00447701730.096
cellular component morphogenesisGO:00329893140.096
cell morphogenesis involved in differentiationGO:00009041440.095
regulation of mitotic cell cycleGO:00073461890.091
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.089
negative regulation of cellular component organizationGO:00511292350.088
definitive hemopoiesisGO:006021620.086
regulation of chromatin modificationGO:1903308510.086
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.085
mitotic dna integrity checkpointGO:0044774300.083
signal transduction by phosphorylationGO:00230142970.082
negative regulation of phosphate metabolic processGO:00459362670.081
cellular amino acid metabolic processGO:00065201160.080
dna recombinationGO:0006310770.079
ribonucleotide biosynthetic processGO:0009260810.079
cell morphogenesis involved in neuron differentiationGO:0048667440.078
protein targetingGO:00066051870.078
nucleosome assemblyGO:0006334500.077
positive regulation of developmental processGO:00510943140.077
rhythmic processGO:0048511310.077
proteasomal protein catabolic processGO:00104981760.076
symbiosis encompassing mutualism through parasitismGO:00444031560.076
negative regulation of protein maturationGO:19033181420.075
central nervous system developmentGO:00074171230.075
muscle tissue developmentGO:0060537620.074
histone deacetylationGO:0016575320.074
regulation of intracellular transportGO:00323861950.074
positive regulation of endopeptidase activityGO:0010950840.074
amine metabolic processGO:0009308440.073
negative regulation of cell deathGO:00605483450.073
negative regulation of cell cycleGO:00457861930.072
regulation of protein kinase activityGO:00458592890.072
anterior posterior pattern specificationGO:000995290.071
associative learningGO:000830610.070
mapk cascadeGO:00001652880.070
cellular response to oxygen containing compoundGO:19017012760.070
somitogenesisGO:000175620.069
chromatin silencingGO:0006342120.068
positive regulation of chromatin modificationGO:1903310300.068
dendritic spine organizationGO:009706140.067
purine nucleoside triphosphate metabolic processGO:00091444120.067
Mouse
muscle structure developmentGO:0061061980.067
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.065
meiosis iGO:000712740.062
organelle assemblyGO:00709251760.062
regulation of cellular ketone metabolic processGO:0010565500.062
regulation of cellular protein catabolic processGO:1903362960.060
positive regulation of cell differentiationGO:00455972110.059
regulation of cellular response to stressGO:00801352440.059
response to nitrogen compoundGO:19016981840.059
chordate embryonic developmentGO:0043009340.058
ribonucleoside triphosphate metabolic processGO:00091994120.058
Mouse
response to alcoholGO:0097305640.057
regulation of intracellular protein transportGO:00331571230.056
positive regulation of cell cycleGO:00457871400.056
protein maturationGO:00516042330.056
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.055
agingGO:0007568660.055
positive regulation of neurogenesisGO:0050769490.055
regulation of neuron differentiationGO:0045664700.053
organelle fissionGO:00482851490.053
negative regulation of intracellular transportGO:0032387600.053
cell morphogenesisGO:00009022960.052
negative regulation of protein modification processGO:00314002000.050
negative regulation of cytoplasmic transportGO:1903650460.049
negative regulation of mitotic cell cycleGO:00459301020.049
purine containing compound catabolic processGO:00725234110.047
Mouse
histone h4 deacetylationGO:007093380.045
peptidyl lysine modificationGO:00182051440.045
response to inorganic substanceGO:00100351270.045
multicellular organism reproductionGO:0032504420.045
tricarboxylic acid metabolic processGO:007235040.042
neuron deathGO:0070997650.041
chemotaxisGO:00069351570.041
response to drugGO:0042493810.041
nuclear exportGO:0051168690.039
negative regulation of phosphorus metabolic processGO:00105632670.039
protein deacylationGO:0035601390.038
protein localization to nucleusGO:00345041360.038
Mouse
methylationGO:00322591060.038
nucleosome organizationGO:0034728660.038
cellular protein catabolic processGO:00442572610.037
negative regulation of cellular catabolic processGO:0031330830.037
chromosome condensationGO:0030261150.037
spermatid differentiationGO:004851540.036
negative regulation of apoptotic processGO:00430663160.036
oxidation reduction processGO:00551143960.036
organophosphate biosynthetic processGO:00904071630.035
protein acetylationGO:00064731160.035
endocytosisGO:00068971590.035
positive regulation of multi organism processGO:0043902560.035
establishment of organelle localizationGO:0051656590.035
monocarboxylic acid metabolic processGO:00327871850.035
protein modification by small protein removalGO:0070646920.035
regulation of neurogenesisGO:0050767820.035
cellular response to hormone stimulusGO:00328701250.033
response to hormoneGO:00097251750.033
signal transduction in response to dna damageGO:0042770570.032
dna integrity checkpointGO:0031570710.030
rna interferenceGO:001624640.030
reproductive system developmentGO:0061458560.030
Worm
negative regulation of cell motilityGO:20001461040.030
anterior posterior axis specificationGO:000994820.030
regulation of lymphocyte activationGO:00512491030.030
regulation of histone modificationGO:0031056470.030
establishment of protein localization to organelleGO:00725941720.029
striated muscle tissue developmentGO:0014706590.029
molting cycleGO:0042303280.029
cellular homeostasisGO:00197251960.029
negative regulation of neuron apoptotic processGO:0043524230.029
positive regulation of transferase activityGO:00513472270.029
protein import into nucleusGO:00066061040.029
axonogenesisGO:0007409310.029
nucleotide catabolic processGO:00091664080.028
Mouse
positive regulation of protein kinase activityGO:00458601900.028
mitotic cell cycle checkpointGO:0007093680.028
lymphocyte anergyGO:000224920.028
cell part morphogenesisGO:00329901370.027
response to heatGO:0009408210.027
protein targeting to nucleusGO:00447441040.027
regulation of erythrocyte differentiationGO:0045646170.027
regulation of gene expression epigeneticGO:0040029730.027
neuromuscular junction developmentGO:000752830.027
cell activationGO:00017752130.027
response to organic cyclic compoundGO:00140702040.026
carbohydrate metabolic processGO:00059752070.026
positive regulation of map kinase activityGO:0043406800.026
internal protein amino acid acetylationGO:00064751010.026
purine nucleotide biosynthetic processGO:0006164840.026
intracellular steroid hormone receptor signaling pathwayGO:0030518610.025
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.025
response to temperature stimulusGO:0009266220.025
response to starvationGO:0042594590.024
protein dna complex subunit organizationGO:0071824800.024
meiotic cell cycle processGO:190304680.023
regulation of bindingGO:00510981110.023
body morphogenesisGO:0010171110.023
Worm
ossificationGO:00015031210.023
regulation of cell cycle phase transitionGO:19019871260.023
regulation of multi organism processGO:00439001570.023
regulation of response to external stimulusGO:00321012220.023
reproductive processGO:00224141060.023
Worm
neuroblast proliferationGO:000740540.023
positive regulation of cell developmentGO:0010720920.023
cellular response to hypoxiaGO:0071456510.023
non recombinational repairGO:0000726140.022
protein o linked glycosylationGO:0006493210.022
regulation of nuclear divisionGO:0051783650.022
cellular response to growth factor stimulusGO:00713631970.022
cellular ketone metabolic processGO:0042180800.022
regulation of chromatin organizationGO:1902275560.022
positive regulation of chromosome organizationGO:2001252410.022
regulation of locomotionGO:00400123290.021
negative regulation of growthGO:0045926970.021
negative regulation of cell proliferationGO:00082852280.021
secretion by cellGO:00329402260.021
nucleotide biosynthetic processGO:00091651090.021
toll signaling pathwayGO:000806320.021
epithelium developmentGO:00604292270.020
nucleoside triphosphate metabolic processGO:00091414220.020
Mouse
cellular response to oxygen levelsGO:0071453550.020
multi organism behaviorGO:0051705140.020
response to other organismGO:00517072610.020
central nervous system projection neuron axonogenesisGO:002195230.020
regulation of protein ubiquitinationGO:0031396950.020
positive regulation of protein ubiquitinationGO:0031398530.020
negative regulation of intracellular protein transportGO:0090317420.020
response to estradiolGO:0032355230.019
negative regulation of transferase activityGO:00513481240.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
Mouse
regulation of protein localizationGO:00328802960.019
posttranscriptional gene silencingGO:0016441250.019
regulation of apoptotic signaling pathwayGO:20012331750.019
response to cytokineGO:00340972320.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
protein dna complex assemblyGO:0065004640.019
regulation of protein processingGO:00706131500.018
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.018
negative regulation of toll signaling pathwayGO:004575110.018
negative regulation of kinase activityGO:00336731060.018
cell divisionGO:00513011680.018
reproductionGO:0000003630.017
Worm
negative regulation of stem cell proliferationGO:200064730.017
regulation of response to dna damage stimulusGO:2001020940.017
pattern specification processGO:0007389430.017
gene loopingGO:009020210.017
epithelial cell migrationGO:00106311190.017
dna replicationGO:00062601160.017
regulation of protein complex assemblyGO:00432541470.017
regulation of cell cycle processGO:00105642660.017
negative regulation of phosphorylationGO:00423261740.017
cellular response to nitrogen compoundGO:19016991440.017
positive regulation of cell proliferationGO:00082843010.017
neurological system processGO:00508771630.016
defense responseGO:00069523150.016
negative regulation of nucleocytoplasmic transportGO:0046823370.016
negative regulation of mitotic cell cycle phase transitionGO:1901991850.016
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.016
positive regulation of kinase activityGO:00336742040.016
positive regulation of cell projection organizationGO:0031346640.016
organelle localizationGO:0051640840.016
regulation of protein transportGO:00512232130.015
negative regulation of protein transportGO:0051224750.015
base excision repairGO:0006284210.015
osteoblast differentiationGO:0001649920.015
positive regulation of peptidyl lysine acetylationGO:2000758120.015
regulation of dna metabolic processGO:00510521530.015
cellular protein complex assemblyGO:00436231880.015
regulation of ras protein signal transductionGO:00465781550.015
spindle organizationGO:0007051530.015
regulation of cell projection organizationGO:00313441070.014
cell maturationGO:0048469110.014
regulation of cytoplasmic transportGO:19036491490.014
negative regulation of multicellular organismal processGO:00512413170.014
Worm
negative regulation of dna repairGO:004573880.014
taxisGO:00423301570.014
peptidyl lysine acetylationGO:00183941010.013
sex differentiationGO:0007548450.013
Worm
cellular process involved in reproduction in multicellular organismGO:0022412150.013
circadian rhythmGO:0007623210.013
purine ribonucleoside metabolic processGO:00461284370.013
Mouse
purine ribonucleotide catabolic processGO:00091544040.013
Mouse
growthGO:00400072020.013
dorsal ventral pattern formationGO:0009953150.013
chemical homeostasisGO:00488783060.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of cellular amine metabolic processGO:0033238110.013
negative regulation of protein processingGO:00109551420.013
snrna modificationGO:004003110.013
response to external biotic stimulusGO:00432072610.013
negative regulation of cell cycle phase transitionGO:1901988890.013
multicellular organismal reproductive processGO:0048609400.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.012
regulation of cell motilityGO:20001452990.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
regulation of androgen receptor signaling pathwayGO:0060765180.012
negative regulation of organelle organizationGO:00106391260.012
multicellular organism growthGO:003526480.012
mrna processingGO:00063971330.012
purine ribonucleoside triphosphate metabolic processGO:00092054110.012
Mouse
cellular response to oxidative stressGO:0034599850.012
regulation of protein export from nucleusGO:0046825150.012
dendrite developmentGO:0016358240.012
internal peptidyl lysine acetylationGO:0018393970.011
dendritic spine developmentGO:006099660.011
regulation of nervous system developmentGO:0051960880.011
multi multicellular organism processGO:0044706180.011
phagocytosisGO:0006909420.011
response to acid chemicalGO:0001101660.011
regulation of cellular respirationGO:004345740.011
axon developmentGO:0061564340.011
ribonucleoprotein complex subunit organizationGO:0071826810.011
positive regulation of cellular amine metabolic processGO:003324070.011
regulation of growthGO:00400081650.011
histone h3 k4 methylationGO:0051568270.011
maintenance of locationGO:00512351120.010
regulation of system processGO:00440571010.010
Mouse
negative regulation of chromatin modificationGO:1903309210.010
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010
anterior posterior axis specification embryoGO:000859520.010
cell junction organizationGO:0034330790.010
positive regulation of dna bindingGO:0043388170.010

SUMO1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.024
nervous system diseaseDOID:8634310.024
orofacial cleftDOID:005056740.003
physical disorderDOID:0080015410.003