Homo sapiens

0 known processes

GSDMD

gasdermin D

(Aliases: DFNA5L,DF5L,GSDMDC1,FLJ12150)

GSDMD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238110.077
cellular amine metabolic processGO:0044106410.074
regulation of cellular amino acid metabolic processGO:000652160.064
cellular amino acid metabolic processGO:00065201160.061
positive regulation of immune system processGO:00026842830.058
amine metabolic processGO:0009308440.057
cellular ketone metabolic processGO:0042180800.052
ras protein signal transductionGO:0007265730.051
protein modification by small protein conjugationGO:00324463420.050
purine ribonucleoside triphosphate catabolic processGO:00092073910.046
positive regulation of cellular amino acid metabolic processGO:004576430.045
regulation of locomotionGO:00400123290.045
nucleoside triphosphate catabolic processGO:00091433940.043
nucleoside catabolic processGO:00091644080.043
defense response to other organismGO:00985421290.042
purine containing compound catabolic processGO:00725234110.042
protein catabolic processGO:00301633250.041
glycosyl compound catabolic processGO:19016584130.041
small gtpase mediated signal transductionGO:0007264780.040
negative regulation of protein metabolic processGO:00512483910.040
purine ribonucleoside triphosphate metabolic processGO:00092054110.040
defense responseGO:00069523150.040
cellular response to cytokine stimulusGO:00713451810.039
protein ubiquitinationGO:00165673140.039
purine nucleoside catabolic processGO:00061523980.039
regulation of cellular ketone metabolic processGO:0010565500.039
cellular macromolecule catabolic processGO:00442653800.039
nucleoside triphosphate metabolic processGO:00091414220.039
regulation of nucleotide catabolic processGO:00308112050.039
regulation of cellular component movementGO:00512703340.038
purine nucleotide catabolic processGO:00061954050.038
purine nucleoside triphosphate catabolic processGO:00091463920.038
organophosphate catabolic processGO:00464344300.036
positive regulation of hydrolase activityGO:00513453310.035
positive regulation of cellular catabolic processGO:00313312840.035
purine ribonucleotide catabolic processGO:00091544040.035
ribonucleotide catabolic processGO:00092614050.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
negative regulation of catalytic activityGO:00430863350.034
peptidyl tyrosine modificationGO:00182121700.034
immune responseGO:00069553070.034
gtp catabolic processGO:00061842370.034
purine ribonucleoside metabolic processGO:00461284370.033
negative regulation of cellular protein metabolic processGO:00322693530.033
enzyme linked receptor protein signaling pathwayGO:00071673030.033
positive regulation of purine nucleotide catabolic processGO:00331231850.032
cellular protein complex assemblyGO:00436231880.032
cellular response to dna damage stimulusGO:00069743790.032
purine ribonucleoside catabolic processGO:00461303980.032
positive regulation of cell motilityGO:20001471770.032
ribonucleoside catabolic processGO:00424544060.031
proteolysis involved in cellular protein catabolic processGO:00516032440.031
peptidyl tyrosine phosphorylationGO:00181081700.031
determination of adult lifespanGO:000834020.031
guanosine containing compound catabolic processGO:19010692390.031
positive regulation of cellular amine metabolic processGO:003324070.031
modification dependent protein catabolic processGO:00199412090.030
negative regulation of phosphorus metabolic processGO:00105632670.030
regulation of immune responseGO:00507762010.030
positive regulation of locomotionGO:00400171860.030
post embryonic developmentGO:000979120.030
cellular component morphogenesisGO:00329893140.029
regulation of cell motilityGO:20001452990.029
single organism cellular localizationGO:19025803320.029
cellular protein catabolic processGO:00442572610.029
positive regulation of cytokine productionGO:00018191670.029
negative regulation of cellular amine metabolic processGO:003323930.028
cellular macromolecular complex assemblyGO:00346223240.028
regulation of gtp catabolic processGO:00331241800.028
regulation of purine nucleotide catabolic processGO:00331212050.028
cytoplasmic transportGO:00164823790.027
membrane organizationGO:00610242920.027
nucleotide catabolic processGO:00091664080.027
nucleoside phosphate catabolic processGO:19012924120.027
positive regulation of catabolic processGO:00098963100.027
female gamete generationGO:000729220.026
regulation of cell migrationGO:00303342890.026
innate immune responseGO:00450871780.026
cytokine mediated signaling pathwayGO:00192211090.026
single organism membrane organizationGO:00448022680.026
regulation of proteolysisGO:00301622930.026
regulation of sequence specific dna binding transcription factor activityGO:00510902110.026
regulation of establishment of protein localizationGO:00702012420.026
positive regulation of transportGO:00510503360.026
cell morphogenesisGO:00009022960.025
apoptotic signaling pathwayGO:00971902680.025
negative regulation of cellular amino acid metabolic processGO:004576320.025
leukocyte activationGO:00453211640.025
cellular cation homeostasisGO:00300031630.025
positive regulation of phosphorylationGO:00423273940.025
multicellular organismal agingGO:001025930.025
purine nucleoside triphosphate metabolic processGO:00091444120.024
ribonucleoside triphosphate metabolic processGO:00091994120.024
cytokine productionGO:00018162470.024
guanosine containing compound metabolic processGO:19010682440.024
gtp metabolic processGO:00460392390.024
regulation of nucleoside metabolic processGO:00091182090.024
regulation of gtpase activityGO:00430871800.023
regulation of cytokine productionGO:00018172320.023
negative regulation of phosphate metabolic processGO:00459362670.023
negative regulation of protein modification processGO:00314002000.023
regulation of anatomical structure morphogenesisGO:00226032860.023
regulation of transferase activityGO:00513383550.023
positive regulation of immune responseGO:00507781590.023
positive regulation of developmental processGO:00510943140.023
regulation of nucleotide metabolic processGO:00061402690.022
regulation of kinase activityGO:00435493140.022
nervous system developmentGO:00073992930.022
anion transportGO:00068201610.022
positive regulation of cellular component organizationGO:00511303760.022
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.021
biological adhesionGO:00226103310.021
intracellular protein transportGO:00068862700.021
response to cytokineGO:00340972320.021
lipid metabolic processGO:00066293810.021
response to external biotic stimulusGO:00432072610.021
cell activationGO:00017752130.021
activation of immune responseGO:00022531140.021
positive regulation of cell proliferationGO:00082843010.021
response to abiotic stimulusGO:00096283360.021
rho protein signal transductionGO:0007266260.021
cell adhesionGO:00071553250.021
modification dependent macromolecule catabolic processGO:00436322120.021
regulation of immune effector processGO:0002697910.020
regulation of cellular component biogenesisGO:00440872810.020
regulation of ras protein signal transductionGO:00465781550.020
regenerationGO:003109940.020
regulation of cellular response to stressGO:00801352440.020
regulation of protein transportGO:00512232130.020
ubiquitin dependent protein catabolic processGO:00065112060.020
immune effector processGO:00022521590.019
signal transduction by phosphorylationGO:00230142970.019
regulation of cell differentiationGO:00455953930.019
regulation of protein localizationGO:00328802960.019
cellular response to abiotic stimulusGO:00712141170.019
cellular lipid metabolic processGO:00442553030.019
regulation of apoptotic signaling pathwayGO:20012331750.019
regulation of response to external stimulusGO:00321012220.019
regulation of actin filament based processGO:00329701410.019
regulation of purine nucleotide metabolic processGO:19005422640.019
vesicle mediated transportGO:00161923710.019
regulation of cell activationGO:00508651250.019
negative regulation of cellular component organizationGO:00511292350.019
positive regulation of nucleotide catabolic processGO:00308131850.019
hematopoietic or lymphoid organ developmentGO:00485341860.018
oogenesisGO:004847720.018
protein localization to membraneGO:00726571600.018
positive regulation of apoptotic processGO:00430652460.018
memoryGO:000761330.018
response to virusGO:00096151260.018
regulation of peptidyl tyrosine phosphorylationGO:00507301080.018
mapk cascadeGO:00001652880.018
regulation of protein kinase activityGO:00458592890.018
negative regulation of organelle organizationGO:00106391260.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
dephosphorylationGO:00163112090.018
mitotic cell cycleGO:00002783260.018
system processGO:00030083490.018
regulation of protein complex assemblyGO:00432541470.017
proteasomal protein catabolic processGO:00104981760.017
actin filament based processGO:00300292240.017
positive regulation of gtp catabolic processGO:00331261660.017
cellular response to external stimulusGO:00714961110.017
chemical homeostasisGO:00488783060.017
cell projection organizationGO:00300302520.017
positive regulation of gtpase activityGO:00435471660.017
regulation of intracellular transportGO:00323861950.017
chromatin organizationGO:00063253510.017
protein localization to organelleGO:00333652800.017
ion homeostasisGO:00508012300.017
viral processGO:00160321460.017
regulation of cytoskeleton organizationGO:00514931770.016
negative regulation of multicellular organismal processGO:00512413170.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
positive regulation of cell deathGO:00109422630.016
cellular homeostasisGO:00197251960.016
cdc42 protein signal transductionGO:003248840.016
positive regulation of nucleotide metabolic processGO:00459812300.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.016
lymphocyte activationGO:00466491330.016
positive regulation of protein phosphorylationGO:00019343130.016
immune response activating signal transductionGO:0002757900.016
negative regulation of protein phosphorylationGO:00019331400.016
multi organism cellular processGO:00447641560.015
response to other organismGO:00517072610.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
regulation of secretionGO:00510461940.015
nitrogen compound transportGO:00717051910.015
microtubule based processGO:00070172100.015
cellular ion homeostasisGO:00068731680.015
response to oxygen containing compoundGO:19017003690.015
regulation of ras gtpase activityGO:00323181280.015
negative regulation of phosphorylationGO:00423261740.015
regulation of cell cycleGO:00517263930.015
dna repairGO:00062811980.015
compound eye developmentGO:004874910.015
chromatin modificationGO:00165682980.015
positive regulation of nucleoside metabolic processGO:00459791860.015
cation homeostasisGO:00550801890.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
nucleic acid phosphodiester bond hydrolysisGO:00903051020.015
actin polymerization or depolymerizationGO:0008154560.015
protein autophosphorylationGO:00467771230.015
regulation of protein catabolic processGO:00421761550.015
negative regulation of cell proliferationGO:00082852280.015
positive regulation of organelle organizationGO:00106381950.014
inorganic ion transmembrane transportGO:00986602310.014
transmembrane transportGO:00550853990.014
cell developmentGO:00484683280.014
positive regulation of mapk cascadeGO:00434101900.014
spermatid differentiationGO:004851540.014
negative regulation of immune system processGO:00026831360.014
maintenance of locationGO:00512351120.014
carbohydrate derivative biosynthetic processGO:19011372070.014
divalent inorganic cation homeostasisGO:00725071360.014
protein processingGO:00164852260.014
stem cell divisionGO:001714520.014
regulation of innate immune responseGO:0045088970.014
growthGO:00400072020.014
segmentationGO:003528240.014
ion transmembrane transportGO:00342203380.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of dna metabolic processGO:00510521530.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
secretion by cellGO:00329402260.014
negative regulation of programmed cell deathGO:00430693210.014
immune system developmentGO:00025201950.014
regulation of cell growthGO:00015581350.014
blastoderm segmentationGO:000735020.014
endomembrane system organizationGO:00102561960.014
cellular chemical homeostasisGO:00550821800.013
locomotory behaviorGO:000762610.013
secretionGO:00469032540.013
protein maturationGO:00516042330.013
positive regulation of synaptic transmissionGO:005080640.013
neurological system processGO:00508771630.013
regulation of mapk cascadeGO:00434082620.013
cation transportGO:00068123310.013
regulation of peptidase activityGO:00525471800.013
oocyte developmentGO:004859910.013
negative regulation of developmental processGO:00510932470.013
cell projection assemblyGO:00300311260.013
regulation of cell adhesionGO:00301551660.013
cell growthGO:00160491600.013
carboxylic acid catabolic processGO:0046395710.013
positive regulation of transferase activityGO:00513472270.013
hindbrain developmentGO:003090230.013
endosomal transportGO:00161971290.013
somatic muscle developmentGO:000752510.013
negative regulation of apoptotic processGO:00430663160.013
positive regulation of protein transportGO:00512221350.013
carbohydrate metabolic processGO:00059752070.013
metencephalon developmentGO:002203720.013
regulation of endopeptidase activityGO:00525481700.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
neurogenesisGO:00220081690.013
metal ion homeostasisGO:00550651690.013
positive regulation of protein kinase activityGO:00458601900.013
positive regulation of ras gtpase activityGO:00323201170.013
positive regulation of kinase activityGO:00336742040.013
posttranscriptional regulation of gene expressionGO:00106082130.013
rna processingGO:00063962550.012
negative regulation of neurological system processGO:003164520.012
response to lipidGO:00339932060.012
negative regulation of transportGO:00510511760.012
actin cytoskeleton organizationGO:00300362070.012
positive regulation of cell differentiationGO:00455972110.012
myeloid cell differentiationGO:00300991170.012
morphogenesis of embryonic epitheliumGO:001633140.012
epithelium developmentGO:00604292270.012
neuromuscular junction developmentGO:000752830.012
regulation of vesicle mediated transportGO:00606271300.012
spermatid developmentGO:000728640.012
negative regulation of cell deathGO:00605483450.012
regulation of multi organism processGO:00439001570.012
negative regulation of intracellular signal transductionGO:19025321830.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
regulation of lymphocyte activationGO:00512491030.012
positive regulation of cellular component movementGO:00512721810.012
viral life cycleGO:00190581320.012
mitochondrion organizationGO:00070051560.012
negative regulation of cell cycleGO:00457861930.012
monocarboxylic acid metabolic processGO:00327871850.012
positive regulation of cell migrationGO:00303351720.012
defense response to fungusGO:005083240.012
oocyte differentiationGO:000999420.012
nucleoside phosphate biosynthetic processGO:19012931090.012
small molecule catabolic processGO:0044282920.012
chloride transportGO:0006821410.012
negative regulation of transferase activityGO:00513481240.012
regulation of protein ubiquitinationGO:0031396950.012
organic hydroxy compound metabolic processGO:19016151470.011
regulation of synaptic plasticityGO:004816730.011
organonitrogen compound biosynthetic processGO:19015662000.011
anion transmembrane transportGO:0098656760.011
protein targetingGO:00066051870.011
organophosphate biosynthetic processGO:00904071630.011
negative regulation of cytokine productionGO:0001818820.011
regulation of growthGO:00400081650.011
mitotic cell cycle processGO:19030472860.011
response to organic cyclic compoundGO:00140702040.011
negative regulation of interferon beta productionGO:003268840.011
oxidation reduction processGO:00551143960.011
response to radiationGO:00093141510.011
regulation of cytoplasmic transportGO:19036491490.011
inorganic anion transmembrane transportGO:0098661470.011
tripartite regional subdivisionGO:000735120.011
organic acid catabolic processGO:0016054710.011
regulation of response to woundingGO:19030341010.011
cellular response to growth factor stimulusGO:00713631970.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
cerebellum developmentGO:002154920.011
protein polymerizationGO:0051258710.011
regulation of secretion by cellGO:19035301770.011
regulation of homeostatic processGO:00328441210.011
fatty acid metabolic processGO:00066311150.011
nucleoside monophosphate metabolic processGO:00091231910.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
double strand break repairGO:00063021010.011
establishment of protein localization to organelleGO:00725941720.011
regulation of cell morphogenesisGO:00226041530.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
neuron developmentGO:00486661130.011
hemopoiesisGO:00300971800.011
regulation of leukocyte activationGO:00026941150.011
photoreceptor cell differentiationGO:004653020.011
cell part morphogenesisGO:00329901370.011
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.011
regulation of hormone levelsGO:00108171250.011
cellular metal ion homeostasisGO:00068751460.011
positive regulation of nf kappab transcription factor activityGO:0051092810.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
chloride transmembrane transportGO:1902476380.011
regulation of cell cycle processGO:00105642660.010
inorganic anion transportGO:0015698600.010
organelle assemblyGO:00709251760.010
neuroblast proliferationGO:000740540.010
positive regulation of proteolysisGO:00458621420.010
covalent chromatin modificationGO:00165692540.010
nucleocytoplasmic transportGO:00069131760.010
cellular response to oxygen containing compoundGO:19017012760.010
t cell activationGO:0042110990.010
regulation of erk1 and erk2 cascadeGO:0070372990.010
generation of neuronsGO:00486991520.010
regulation of rho gtpase activityGO:0032319660.010
plasma membrane organizationGO:00070091150.010
negative regulation of kinase activityGO:00336731060.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
metal ion transportGO:00300012720.010
cation transmembrane transportGO:00986552380.010
cell divisionGO:00513011680.010
regulation of response to cytokine stimulusGO:0060759460.010
erk1 and erk2 cascadeGO:00703711040.010
actin filament organizationGO:00070151280.010
cell projection morphogenesisGO:00488581290.010

GSDMD disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.031
disease of metabolismDOID:00146672950.023
inherited metabolic disorderDOID:6552420.023
connective tissue diseaseDOID:651090.021
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.017
disease of cellular proliferationDOID:145661740.016
organ system cancerDOID:00506861640.015
cancerDOID:1621670.015
immune system diseaseDOID:29141550.014
central nervous system diseaseDOID:3311860.013
bone diseaseDOID:0080001880.012
muscle tissue diseaseDOID:661130.010
muscular diseaseDOID:00800001140.010