Homo sapiens

155 known processes

GEN1

Gen homolog 1, endonuclease (Drosophila)

(Aliases: DKFZp781F0986,Gen,FLJ40869)

GEN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nucleoside triphosphate metabolic processGO:00091414220.073
meiotic chromosome segregationGO:004513240.046
post embryonic developmentGO:000979120.045
purine ribonucleotide catabolic processGO:00091544040.043
nucleoside triphosphate catabolic processGO:00091433940.041
purine ribonucleoside metabolic processGO:00461284370.041
purine ribonucleoside catabolic processGO:00461303980.040
ribonucleoside catabolic processGO:00424544060.040
purine containing compound catabolic processGO:00725234110.040
mitotic cell cycleGO:00002783260.040
ribonucleotide catabolic processGO:00092614050.040
purine nucleotide catabolic processGO:00061954050.038
ribonucleoside triphosphate catabolic processGO:00092033910.038
nucleoside phosphate catabolic processGO:19012924120.037
negative regulation of programmed cell deathGO:00430693210.036
maintenance of locationGO:00512351120.036
regulation of cell cycleGO:00517263930.035
multicellular organismal agingGO:001025930.034
response to abiotic stimulusGO:00096283360.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
female gamete generationGO:000729220.032
regulation of cytoskeleton organizationGO:00514931770.032
glycosyl compound catabolic processGO:19016584130.031
determination of adult lifespanGO:000834020.030
organelle assemblyGO:00709251760.030
actin filament based processGO:00300292240.029
positive regulation of organelle organizationGO:00106381950.029
regulation of cell cycle processGO:00105642660.029
recombinational repairGO:0000725500.029
cellular macromolecule catabolic processGO:00442653800.029
microtubule based processGO:00070172100.029
negative regulation of phosphate metabolic processGO:00459362670.028
negative regulation of catalytic activityGO:00430863350.027
cellular ketone metabolic processGO:0042180800.027
regulation of cellular ketone metabolic processGO:0010565500.027
amine metabolic processGO:0009308440.027
cellular amino acid metabolic processGO:00065201160.027
organelle fissionGO:00482851490.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
rna processingGO:00063962550.026
organophosphate catabolic processGO:00464344300.026
regulation of cellular amino acid metabolic processGO:000652160.026
response to radiationGO:00093141510.025
regulation of anatomical structure morphogenesisGO:00226032860.025
nucleotide catabolic processGO:00091664080.025
embryonic epithelial tube formationGO:000183840.025
purine nucleoside triphosphate metabolic processGO:00091444120.024
positive regulation of cellular amino acid metabolic processGO:004576430.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
response to caffeineGO:003100030.024
purine nucleoside catabolic processGO:00061523980.023
circulatory system developmentGO:00723592620.023
cellular macromolecular complex assemblyGO:00346223240.023
cellular response to dna damage stimulusGO:00069743790.023
negative regulation of multicellular organismal processGO:00512413170.023
regulation of purine nucleotide metabolic processGO:19005422640.023
cellular amine metabolic processGO:0044106410.022
regulation of locomotionGO:00400123290.022
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.022
regulation of cell cycle phase transitionGO:19019871260.022
regulation of cellular amine metabolic processGO:0033238110.022
mitotic cell cycle phase transitionGO:00447721620.021
regulation of cell migrationGO:00303342890.021
regulation of mitotic cell cycle phase transitionGO:19019901180.021
regulation of nucleotide metabolic processGO:00061402690.021
oogenesisGO:004847720.020
negative regulation of phosphorus metabolic processGO:00105632670.020
negative regulation of cell cycleGO:00457861930.020
cellular response to endogenous stimulusGO:00714953360.020
covalent chromatin modificationGO:00165692540.020
cytoplasmic transportGO:00164823790.020
positive regulation of gtpase activityGO:00435471660.020
positive regulation of phosphorylationGO:00423273940.020
regulation of gtpase activityGO:00430871800.020
regulation of mitotic cell cycleGO:00073461890.020
regulation of protein kinase activityGO:00458592890.020
regulation of cellular response to stressGO:00801352440.019
regulation of kinase activityGO:00435493140.019
negative regulation of cell deathGO:00605483450.019
nucleic acid phosphodiester bond hydrolysisGO:00903051020.019
lipid metabolic processGO:00066293810.019
tissue regenerationGO:004224630.019
anatomical structure homeostasisGO:00602491000.019
negative regulation of cellular protein metabolic processGO:00322693530.019
cellular component morphogenesisGO:00329893140.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
protein ubiquitinationGO:00165673140.018
regulation of transferase activityGO:00513383550.018
regulation of microtubule based processGO:0032886740.018
protein localization to organelleGO:00333652800.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
regulation of protein localizationGO:00328802960.018
negative regulation of protein metabolic processGO:00512483910.018
negative regulation of cell cycle processGO:00109481210.018
guanosine containing compound metabolic processGO:19010682440.018
regulation of mapk cascadeGO:00434082620.018
negative regulation of apoptotic processGO:00430663160.017
growthGO:00400072020.017
maintenance of location in cellGO:0051651620.017
nuclear divisionGO:00002801280.017
double strand break repairGO:00063021010.017
maintenance of protein location in cellGO:0032507560.017
oxidation reduction processGO:00551143960.017
regulation of nucleoside metabolic processGO:00091182090.017
response to cytokineGO:00340972320.017
endomembrane system organizationGO:00102561960.017
cellular response to abiotic stimulusGO:00712141170.017
positive regulation of cellular amine metabolic processGO:003324070.016
positive regulation of nucleotide metabolic processGO:00459812300.016
defense responseGO:00069523150.016
mapk cascadeGO:00001652880.016
blood vessel morphogenesisGO:00485141620.016
regulation of gtp catabolic processGO:00331241800.016
cellular response to radiationGO:0071478650.016
double strand break repair via homologous recombinationGO:0000724500.016
positive regulation of cellular component organizationGO:00511303760.016
mitotic cell cycle processGO:19030472860.016
organ morphogenesisGO:00098871470.016
positive regulation of gtp catabolic processGO:00331261660.016
regulation of cellular component biogenesisGO:00440872810.016
guanosine containing compound catabolic processGO:19010692390.016
response to organonitrogen compoundGO:00102431560.016
regulation of cell motilityGO:20001452990.016
regulation of cytokine productionGO:00018172320.016
signal transduction by phosphorylationGO:00230142970.016
positive regulation of purine nucleotide catabolic processGO:00331231850.015
regulation of cellular component movementGO:00512703340.015
cell morphogenesisGO:00009022960.015
secretionGO:00469032540.015
blood vessel developmentGO:00015681720.015
regulation of purine nucleotide catabolic processGO:00331212050.015
ras protein signal transductionGO:0007265730.015
positive regulation of cellular catabolic processGO:00313312840.015
positive regulation of nucleoside metabolic processGO:00459791860.015
positive regulation of cell proliferationGO:00082843010.015
negative regulation of protein modification processGO:00314002000.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
negative regulation of hydrolase activityGO:00513461820.015
nucleoside monophosphate catabolic processGO:00091251590.015
vesicle mediated transportGO:00161923710.015
cardiovascular system developmentGO:00723582620.015
regulation of cell divisionGO:00513021160.015
vasculature developmentGO:00019441810.014
lens development in camera type eyeGO:000208820.014
response to ionizing radiationGO:0010212650.014
regulation of organelle assemblyGO:1902115400.014
small gtpase mediated signal transductionGO:0007264780.014
negative regulation of intracellular signal transductionGO:19025321830.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
response to nitrogen compoundGO:19016981840.014
regulation of cell morphogenesisGO:00226041530.014
negative regulation of mitotic cell cycle phase transitionGO:1901991850.014
primary neural tube formationGO:001402030.014
positive regulation of kinase activityGO:00336742040.014
negative regulation of cellular amine metabolic processGO:003323930.014
regulation of dephosphorylationGO:0035303960.014
positive regulation of apoptotic processGO:00430652460.014
cellular response to cytokine stimulusGO:00713451810.014
chemical homeostasisGO:00488783060.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
angiogenesisGO:00015251470.014
positive regulation of nucleotide catabolic processGO:00308131850.014
biological adhesionGO:00226103310.014
head developmentGO:00603221080.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
innate immune responseGO:00450871780.014
positive regulation of transportGO:00510503360.014
hindbrain developmentGO:003090230.014
gtp catabolic processGO:00061842370.014
rho protein signal transductionGO:0007266260.013
protein modification by small protein conjugationGO:00324463420.013
positive regulation of cell deathGO:00109422630.013
protein maturationGO:00516042330.013
snrna metabolic processGO:0016073150.013
locomotory behaviorGO:000762610.013
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
negative regulation of immune system processGO:00026831360.013
cell divisionGO:00513011680.013
regulation of protein transportGO:00512232130.013
cellular protein complex assemblyGO:00436231880.013
actin cytoskeleton organizationGO:00300362070.013
oocyte developmentGO:004859910.013
ncrna processingGO:0034470830.013
regulation of growthGO:00400081650.013
negative regulation of phosphatase activityGO:0010923610.013
neural tube closureGO:000184330.013
regulation of apoptotic signaling pathwayGO:20012331750.013
actin filament based movementGO:0030048170.013
hemopoiesisGO:00300971800.013
protein catabolic processGO:00301633250.013
single organism membrane organizationGO:00448022680.013
microtubule cytoskeleton organizationGO:00002261760.013
epithelium developmentGO:00604292270.013
system processGO:00030083490.013
regulation of response to external stimulusGO:00321012220.013
morphogenesis of embryonic epitheliumGO:001633140.013
histone modificationGO:00165702510.012
response to purine containing compoundGO:0014074400.012
regulation of proteolysisGO:00301622930.012
cellular response to oxygen containing compoundGO:19017012760.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
secretion by cellGO:00329402260.012
chromatin organizationGO:00063253510.012
regulation of immune responseGO:00507762010.012
maintenance of protein locationGO:0045185570.012
positive regulation of ras gtpase activityGO:00323201170.012
protein autophosphorylationGO:00467771230.012
response to organic cyclic compoundGO:00140702040.012
regulation of cell growthGO:00015581350.012
chromatin modificationGO:00165682980.012
stem cell divisionGO:001714520.012
positive regulation of protein phosphorylationGO:00019343130.012
tissue migrationGO:00901301190.012
cell activationGO:00017752130.012
dephosphorylationGO:00163112090.012
methylation dependent chromatin silencingGO:000634630.012
protein targetingGO:00066051870.012
dna replicationGO:00062601160.012
cellular response to oxidative stressGO:0034599850.012
positive regulation of cell cycleGO:00457871400.012
positive regulation of meiotic cell cycleGO:005144620.012
centrosome cycleGO:0007098320.012
g2 m transition of mitotic cell cycleGO:0000086410.012
regulation of response to dna damage stimulusGO:2001020940.012
cilium assemblyGO:0042384630.012
dna recombinationGO:0006310770.012
segmentationGO:003528240.011
cell adhesionGO:00071553250.011
embryo developmentGO:00097901230.011
tissue morphogenesisGO:0048729960.011
negative regulation of organelle organizationGO:00106391260.011
myeloid cell differentiationGO:00300991170.011
meiosis iGO:000712740.011
regulation of ras protein signal transductionGO:00465781550.011
single organism carbohydrate metabolic processGO:00447231930.011
blastocyst developmentGO:000182430.011
negative regulation of mitotic cell cycleGO:00459301020.011
actin filament organizationGO:00070151280.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
mitotic nuclear divisionGO:00070671190.011
cytokine productionGO:00018162470.011
epithelial cell differentiationGO:00308551410.011
oocyte differentiationGO:000999420.011
cellular homeostasisGO:00197251960.011
immune responseGO:00069553070.011
nervous system developmentGO:00073992930.011
interspecies interaction between organismsGO:00444191560.011
regulation of cellular protein catabolic processGO:1903362960.011
cell part morphogenesisGO:00329901370.011
negative regulation of cell proliferationGO:00082852280.011
cilium morphogenesisGO:0060271750.011
protein secretionGO:0009306980.011
regenerationGO:003109940.010
cell projection organizationGO:00300302520.010
positive regulation of cytokine productionGO:00018191670.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
negative regulation of developmental processGO:00510932470.010
regulation of nucleotide catabolic processGO:00308112050.010
regulation of multi organism processGO:00439001570.010
ameboidal type cell migrationGO:00016671350.010
positive regulation of secretionGO:00510471160.010
regulation of meiotic cell cycleGO:005144540.010
response to oxygen containing compoundGO:19017003690.010
negative regulation of apoptotic signaling pathwayGO:2001234970.010
actin mediated cell contractionGO:0070252120.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
positive regulation of cellular component biogenesisGO:00440891580.010
leukocyte activationGO:00453211640.010

GEN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.112
hematopoietic system diseaseDOID:741000.062
congenital nervous system abnormalityDOID:2490210.028
physical disorderDOID:0080015410.028
disease of cellular proliferationDOID:145661740.028
cancerDOID:1621670.028
anemiaDOID:2355550.016
organ system cancerDOID:00506861640.015
disease of metabolismDOID:00146672950.013