Homo sapiens

66 known processes

CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

(Aliases: P450C3,CYPIIIA4,NF-25,CYP3A3,CYPIIIA3,P450PCN1,MGC126680,CP34,HLP,CYP3A,CP33)

CYP3A4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxidative demethylationGO:0070989110.979
alkaloid catabolic processGO:000982230.967
drug catabolic processGO:0042737100.926
vitamin k catabolic processGO:004237720.841
alkaloid metabolic processGO:000982040.804
epoxygenase p450 pathwayGO:001937330.779
drug metabolic processGO:0017144190.752
lipid metabolic processGO:00066293810.697
quinone catabolic processGO:190166220.600
response to xenobiotic stimulusGO:0009410300.591
Zebrafish Fly
steroid metabolic processGO:0008202940.570
phylloquinone metabolic processGO:004237420.518
monoterpenoid metabolic processGO:001609860.517
menaquinone catabolic processGO:004236120.512
vitamin d3 metabolic processGO:007064070.483
monocarboxylic acid metabolic processGO:00327871850.480
Fly
vitamin e metabolic processGO:004236010.475
negative regulation of icosanoid secretionGO:003230420.474
icosanoid catabolic processGO:190152320.442
cellular organohalogen metabolic processGO:009034520.441
long chain fatty acid metabolic processGO:0001676300.439
organic hydroxy compound metabolic processGO:19016151470.439
sensory perception of smellGO:000760820.425
Fly
calcitriol biosynthetic process from calciolGO:003637870.422
cellular lipid metabolic processGO:00442553030.411
oxidation reduction processGO:00551143960.407
naphthalene metabolic processGO:001893110.400
leukotriene b4 metabolic processGO:003610220.361
alcohol metabolic processGO:00060661140.358
toxin metabolic processGO:000940440.354
Fly
xenobiotic metabolic processGO:0006805280.346
Fly
lipid catabolic processGO:0016042840.337
menaquinone metabolic processGO:000923330.337
secondary alcohol metabolic processGO:190265270.323
isoquinoline alkaloid metabolic processGO:003307610.317
lipid biosynthetic processGO:00086101770.303
demethylationGO:0070988370.298
phenylpropanoid metabolic processGO:000969830.279
naphthalene containing compound metabolic processGO:009042010.271
fatty acid metabolic processGO:00066311150.253
Fly
negative regulation of cellular organofluorine metabolic processGO:009035010.233
leukotriene catabolic processGO:003610020.231
terpenoid metabolic processGO:0006721270.219
vitamin k biosynthetic processGO:004237120.208
cellular response to xenobiotic stimulusGO:0071466290.199
Fly
leukotriene b4 catabolic processGO:003610120.192
small molecule biosynthetic processGO:00442831570.189
coumarin metabolic processGO:000980420.188
negative regulation of cellular organohalogen metabolic processGO:009034910.187
chemical homeostasisGO:00488783060.154
cellular response to genisteinGO:007141210.153
cellular ketone metabolic processGO:0042180800.149
Fly
fat soluble vitamin metabolic processGO:0006775190.148
nitrogen cycle metabolic processGO:007194130.138
fatty acid derivative catabolic processGO:190156920.129
regulation of cellular organofluorine metabolic processGO:009034810.119
urea metabolic processGO:001962730.117
response to organonitrogen compoundGO:00102431560.115
Fly
cellular amino acid metabolic processGO:00065201160.112
fatty acid omega oxidationGO:001043020.108
steroid biosynthetic processGO:0006694460.107
response to organic cyclic compoundGO:00140702040.101
Rat Fly
response to hormoneGO:00097251750.098
Rat
phylloquinone catabolic processGO:004237620.098
single organism carbohydrate metabolic processGO:00447231930.093
exogenous drug catabolic processGO:004273880.093
cellular response to hydroxyisoflavoneGO:007141310.093
cellular organofluorine metabolic processGO:009034620.092
fatty acid derivative metabolic processGO:1901568350.092
response to caffeineGO:003100030.090
Fly
defense responseGO:00069523150.087
Fly
arachidonic acid metabolic processGO:0019369140.085
medium chain fatty acid metabolic processGO:005179140.084
Fly
response to mercury ionGO:004668940.083
Fly
anion transportGO:00068201610.083
unsaturated fatty acid metabolic processGO:0033559370.082
organic anion transportGO:00157111030.080
renal water homeostasisGO:000309140.078
immune responseGO:00069553070.077
organic hydroxy compound biosynthetic processGO:1901617710.077
regulation of response to external stimulusGO:00321012220.074
response to nitrogen compoundGO:19016981840.074
Fly
regulation of cellular organohalogen metabolic processGO:009034710.073
pressure natriuresisGO:000309520.072
response to metal ionGO:0010038840.067
Rat Fly
protein processingGO:00164852260.064
linoleic acid metabolic processGO:004365140.063
long chain fatty acid catabolic processGO:004275830.062
carbohydrate metabolic processGO:00059752070.062
post embryonic developmentGO:000979120.061
Fly
ketone catabolic processGO:004218230.061
regulation of cellular amino acid metabolic processGO:000652160.058
response to lipidGO:00339932060.057
Rat
system processGO:00030083490.056
Fly
icosanoid metabolic processGO:0006690350.056
response to other organismGO:00517072610.056
Fly
cellular response to endogenous stimulusGO:00714953360.054
response to drugGO:0042493810.052
protein maturationGO:00516042330.052
response to inorganic substanceGO:00100351270.050
Rat Fly
glycerolipid metabolic processGO:00464861070.050
regulation of cellular amine metabolic processGO:0033238110.050
sensory perception of chemical stimulusGO:0007606380.050
Fly
organic acid biosynthetic processGO:0016053970.050
cellular amine metabolic processGO:0044106410.049
response to abiotic stimulusGO:00096283360.049
Fly
response to steroid hormoneGO:0048545800.048
Rat
estrogen catabolic processGO:000671110.048
cellular response to oxygen containing compoundGO:19017012760.047
ion homeostasisGO:00508012300.046
purine containing compound catabolic processGO:00725234110.046
negative regulation of protein metabolic processGO:00512483910.045
regulation of cellular ketone metabolic processGO:0010565500.045
steroid catabolic processGO:0006706100.044
defense response to other organismGO:00985421290.044
Fly
nucleoside phosphate catabolic processGO:19012924120.044
isoprenoid metabolic processGO:0006720390.043
alcohol biosynthetic processGO:0046165520.043
regulation of hormone levelsGO:00108171250.042
Fly
response to woundingGO:00096111680.042
hemostasisGO:0007599760.041
multicellular organismal agingGO:001025930.041
ras protein signal transductionGO:0007265730.040
determination of adult lifespanGO:000834020.040
epithelial cell differentiationGO:00308551410.040
ribonucleotide catabolic processGO:00092614050.039
purine ribonucleoside metabolic processGO:00461284370.039
cellular amide metabolic processGO:0043603690.039
positive regulation of fatty acid transportGO:200019330.039
purine nucleotide catabolic processGO:00061954050.038
amine metabolic processGO:0009308440.038
response to biotic stimulusGO:00096072760.038
Fly
negative regulation of response to external stimulusGO:0032102830.038
positive regulation of hormone biosynthetic processGO:004688640.037
polyol metabolic processGO:0019751320.037
lipid transportGO:0006869900.037
regulation of kinase activityGO:00435493140.037
sulfur compound metabolic processGO:00067901010.037
positive regulation of catabolic processGO:00098963100.037
cytoplasmic transportGO:00164823790.037
regulation of cell differentiationGO:00455953930.036
nucleoside catabolic processGO:00091644080.036
regulation of transferase activityGO:00513383550.036
renal system process involved in regulation of blood volumeGO:000197740.036
positive regulation of cellular catabolic processGO:00313312840.035
response to oxygen containing compoundGO:19017003690.035
nucleoside triphosphate metabolic processGO:00091414220.034
sensory perceptionGO:00076001030.034
Fly
neurological system processGO:00508771630.034
Fly
small gtpase mediated signal transductionGO:0007264780.034
regulation of protein kinase activityGO:00458592890.034
cellular lipid catabolic processGO:0044242650.034
organophosphate catabolic processGO:00464344300.034
response to external biotic stimulusGO:00432072610.033
Fly
innate immune responseGO:00450871780.033
purine nucleoside triphosphate catabolic processGO:00091463920.033
single organism membrane organizationGO:00448022680.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.033
cation homeostasisGO:00550801890.032
ribonucleoside triphosphate metabolic processGO:00091994120.032
negative regulation of cell proliferationGO:00082852280.032
negative regulation of cellular protein metabolic processGO:00322693530.032
regulation of growthGO:00400081650.032
Fly
negative regulation of multicellular organismal processGO:00512413170.032
membrane organizationGO:00610242920.032
secretionGO:00469032540.032
glycosyl compound catabolic processGO:19016584130.031
wound healingGO:00420601150.031
vitamin metabolic processGO:0006766260.031
regulation of locomotionGO:00400123290.031
nucleoside triphosphate catabolic processGO:00091433940.031
carbohydrate derivative biosynthetic processGO:19011372070.030
ribonucleoside catabolic processGO:00424544060.030
regulation of anatomical structure morphogenesisGO:00226032860.030
regenerationGO:003109940.030
carboxylic acid biosynthetic processGO:0046394970.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
negative regulation of catalytic activityGO:00430863350.030
vesicle mediated transportGO:00161923710.030
regulation of response to woundingGO:19030341010.030
locomotory behaviorGO:000762610.029
biological adhesionGO:00226103310.029
cellular homeostasisGO:00197251960.029
lipid modificationGO:0030258840.029
response to bacteriumGO:00096171440.028
Fly
metal ion homeostasisGO:00550651690.028
regulation of nucleotide metabolic processGO:00061402690.028
positive regulation of immune system processGO:00026842830.028
female gamete generationGO:000729220.028
regulation of cell cycleGO:00517263930.028
positive regulation of cellular component organizationGO:00511303760.028
regulation of cell migrationGO:00303342890.028
actin filament based processGO:00300292240.028
regulation of cellular component biogenesisGO:00440872810.028
lipid localizationGO:00108761060.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
nervous system developmentGO:00073992930.027
single organism cellular localizationGO:19025803320.027
carboxylic acid catabolic processGO:0046395710.027
cellular cation homeostasisGO:00300031630.027
behaviorGO:00076101120.027
Fly
negative regulation of phosphorus metabolic processGO:00105632670.027
neuromuscular junction developmentGO:000752830.027
regulation of wound healingGO:0061041560.027
regulation of cell motilityGO:20001452990.027
regulation of lipid metabolic processGO:0019216960.027
regulation of proteolysisGO:00301622930.026
coagulationGO:0050817780.026
organophosphate biosynthetic processGO:00904071630.026
rho protein signal transductionGO:0007266260.026
cell adhesionGO:00071553250.026
cellular response to nitrogen compoundGO:19016991440.026
positive regulation of organic acid transportGO:003289230.026
transmembrane transportGO:00550853990.026
cellular ion homeostasisGO:00068731680.026
uronic acid metabolic processGO:0006063160.026
positive regulation of transportGO:00510503360.026
cellular hormone metabolic processGO:0034754410.026
Fly
positive regulation of hydrolase activityGO:00513453310.025
regulation of icosanoid secretionGO:003230340.025
response to growth factorGO:00708482050.025
small molecule catabolic processGO:0044282920.025
negative regulation of phosphate metabolic processGO:00459362670.025
positive regulation of cellular amine metabolic processGO:003324070.025
signal transduction by phosphorylationGO:00230142970.025
regulation of purine nucleotide metabolic processGO:19005422640.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
regulation of coagulationGO:0050818440.025
negative regulation of transportGO:00510511760.025
regulation of bindingGO:00510981110.025
positive regulation of phosphorylationGO:00423273940.024
enzyme linked receptor protein signaling pathwayGO:00071673030.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
cellular component morphogenesisGO:00329893140.024
organic acid catabolic processGO:0016054710.024
positive regulation of protein phosphorylationGO:00019343130.024
nucleotide catabolic processGO:00091664080.024
protein localization to membraneGO:00726571600.024
oogenesisGO:004847720.024
negative regulation of locomotionGO:00400131180.024
negative regulation of hemostasisGO:1900047220.023
fat soluble vitamin biosynthetic processGO:0042362110.023
cell morphogenesisGO:00009022960.023
positive regulation of cell deathGO:00109422630.023
cellular response to dna damage stimulusGO:00069743790.023
maintenance of locationGO:00512351120.023
response to cytokineGO:00340972320.023
cellular response to cytokine stimulusGO:00713451810.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
secondary metabolic processGO:0019748170.023
Fly
chemotaxisGO:00069351570.022
negative regulation of cellular component organizationGO:00511292350.022
negative regulation of response to woundingGO:1903035470.022
positive regulation of protein kinase activityGO:00458601900.022
regulation of immune responseGO:00507762010.022
regulation of protein maturationGO:19033171500.022
defense response to bacteriumGO:0042742630.022
Fly
positive regulation of cell differentiationGO:00455972110.022
protein catabolic processGO:00301633250.022
cytokine productionGO:00018162470.022
cell developmentGO:00484683280.022
growthGO:00400072020.022
Fly
positive regulation of nucleotide metabolic processGO:00459812300.022
cellular response to organic cyclic compoundGO:00714071270.022
response to nutrient levelsGO:0031667810.022
Rat
regulation of ion transportGO:00432691890.021
regulation of body fluid levelsGO:0050878990.021
cellular response to growth factor stimulusGO:00713631970.021
purine ribonucleoside monophosphate metabolic processGO:00091671860.021
blood coagulationGO:0007596760.021
carboxylic acid transportGO:0046942630.021
taxisGO:00423301570.021
response to organophosphorusGO:0046683410.021
Fly
purine ribonucleotide catabolic processGO:00091544040.021
endomembrane system organizationGO:00102561960.021
memoryGO:000761330.021
actin cytoskeleton organizationGO:00300362070.021
organic acid transportGO:0015849650.021
cell projection organizationGO:00300302520.021
response to nutrientGO:0007584200.021
Rat
cellular metal ion homeostasisGO:00068751460.021
cofactor metabolic processGO:0051186870.021
positive regulation of programmed cell deathGO:00430682490.021
organonitrogen compound biosynthetic processGO:19015662000.021
lipid oxidationGO:0034440330.021
negative regulation of protein maturationGO:19033181420.021
negative regulation of hydrolase activityGO:00513461820.021
regulation of protein localizationGO:00328802960.021
cellular response to organonitrogen compoundGO:00714171240.021
cellular macromolecular complex assemblyGO:00346223240.021
secretion by cellGO:00329402260.021
mitotic cell cycleGO:00002783260.020
regulation of protein processingGO:00706131500.020
regulation of cellular component movementGO:00512703340.020
regulation of cellular response to stressGO:00801352440.020
purine ribonucleoside catabolic processGO:00461303980.020
positive regulation of transferase activityGO:00513472270.020
negative regulation of protein modification processGO:00314002000.020
hemopoiesisGO:00300971800.020
cation transportGO:00068123310.020
leukotriene metabolic processGO:0006691100.020
phospholipid metabolic processGO:0006644990.020
positive regulation of kinase activityGO:00336742040.020
protein localization to organelleGO:00333652800.020
purine nucleoside catabolic processGO:00061523980.020
mitotic cell cycle processGO:19030472860.020
regulation of cell cycle processGO:00105642660.020
regulation of mapk cascadeGO:00434082620.020
guanosine containing compound metabolic processGO:19010682440.020
negative regulation of cell deathGO:00605483450.019
monocarboxylic acid biosynthetic processGO:0072330670.019
regulation of lipid biosynthetic processGO:0046890470.019
immune effector processGO:00022521590.019
coenzyme metabolic processGO:0006732650.019
dephosphorylationGO:00163112090.019
vitamin catabolic processGO:000911160.019
regulation of establishment of protein localizationGO:00702012420.019
cellular response to hormone stimulusGO:00328701250.019
regulation of purine nucleotide catabolic processGO:00331212050.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
positive regulation of developmental processGO:00510943140.019
divalent inorganic cation homeostasisGO:00725071360.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
fat soluble vitamin catabolic processGO:004236360.018
spermatid differentiationGO:004851540.018
protein oligomerizationGO:00512591730.018
protein targetingGO:00066051870.018
negative regulation of cellular amine metabolic processGO:003323930.018
regulation of secretion by cellGO:19035301770.018
negative regulation of intracellular signal transductionGO:19025321830.018
positive regulation of cell migrationGO:00303351720.018
regulation of protein transportGO:00512232130.018
regulation of protein serine threonine kinase activityGO:00719001790.018
inorganic ion transmembrane transportGO:00986602310.018
positive regulation of secretionGO:00510471160.018
nitrogen compound transportGO:00717051910.018
mapk cascadeGO:00001652880.018
positive regulation of apoptotic processGO:00430652460.018
intracellular protein transportGO:00068862700.018
cellular protein complex assemblyGO:00436231880.017
negative regulation of protein processingGO:00109551420.017
negative regulation of apoptotic processGO:00430663160.017
reactive nitrogen species metabolic processGO:200105730.017
regulation of cytokine productionGO:00018172320.017
oocyte differentiationGO:000999420.017
multi organism cellular processGO:00447641560.017
blood vessel developmentGO:00015681720.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
atp metabolic processGO:00460341760.017
generation of neuronsGO:00486991520.017
immune system developmentGO:00025201950.017
response to phenylpropanoidGO:008018410.017
ion transmembrane transportGO:00342203380.017
cellular carbohydrate metabolic processGO:0044262840.017
micturitionGO:006007330.017
negative regulation of wound healingGO:0061045250.017
guanosine containing compound catabolic processGO:19010692390.017
monocarboxylic acid catabolic processGO:0072329370.017
hormone metabolic processGO:0042445610.017
Fly
reactive oxygen species metabolic processGO:0072593750.017
regulation of intracellular transportGO:00323861950.017
negative regulation of developmental processGO:00510932470.017
cellular macromolecule catabolic processGO:00442653800.017
apoptotic signaling pathwayGO:00971902680.017
negative regulation of phosphorylationGO:00423261740.016
regulation of nucleoside metabolic processGO:00091182090.016
epithelial cell proliferationGO:00506731280.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
response to extracellular stimulusGO:0009991850.016
Rat
regulation of peptidase activityGO:00525471800.016
regulation of endopeptidase activityGO:00525481700.016
positive regulation of icosanoid secretionGO:003230530.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of defense responseGO:00313471540.016
vitamin d metabolic processGO:0042359100.016
adult locomotory behaviorGO:000834410.016
single organism cell adhesionGO:00986021790.016
plasma membrane organizationGO:00070091150.016
angiogenesisGO:00015251470.016
associative learningGO:000830610.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
oocyte developmentGO:004859910.016
positive regulation of nucleotide catabolic processGO:00308131850.016
interspecies interaction between organismsGO:00444191560.016
vitamin biosynthetic processGO:0009110110.015
positive regulation of proteolysisGO:00458621420.015
negative regulation of blood coagulationGO:0030195220.015
cellular chemical homeostasisGO:00550821800.015
regulation of cytoplasmic transportGO:19036491490.015
viral processGO:00160321460.015
negative regulation of cell motilityGO:20001461040.015
positive regulation of cellular component biogenesisGO:00440891580.015
cellular modified amino acid metabolic processGO:0006575640.015
regulation of cell developmentGO:00602841610.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
segmentationGO:003528240.015
blood circulationGO:00080151130.015
regulation of cell adhesionGO:00301551660.015
rhythmic behaviorGO:000762220.015
response to genisteinGO:003359510.015
protein modification by small protein conjugationGO:00324463420.015
response to fungusGO:000962040.015
positive regulation of ion transportGO:0043270870.015
regulation of cytoskeleton organizationGO:00514931770.015
response to purine containing compoundGO:0014074400.015
Fly
divalent metal ion transportGO:00708381520.015
ossificationGO:00015031210.015
nucleotide biosynthetic processGO:00091651090.015
positive regulation of cell motilityGO:20001471770.015
posttranscriptional regulation of gene expressionGO:00106082130.015
gtp metabolic processGO:00460392390.015
vitamin k metabolic processGO:004237360.015
limbic system developmentGO:002176130.015
myeloid cell differentiationGO:00300991170.015
protein ubiquitinationGO:00165673140.015
spermatid developmentGO:000728640.015
regulation of blood coagulationGO:0030193420.015
cell growthGO:00160491600.015
response to decreased oxygen levelsGO:0036293960.015
neutral lipid metabolic processGO:0006638270.015
positive regulation of nucleoside metabolic processGO:00459791860.015
tissue migrationGO:00901301190.015
regulation of gtpase activityGO:00430871800.014
epithelium developmentGO:00604292270.014
positive regulation of immune responseGO:00507781590.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
sensory perception of painGO:001923340.014
sequestering of metal ionGO:0051238240.014
vasculature developmentGO:00019441810.014
positive regulation of mapk cascadeGO:00434101900.014
regulation of nucleotide catabolic processGO:00308112050.014
gtp catabolic processGO:00061842370.014
negative regulation of cellular component movementGO:00512711060.014
visual behaviorGO:000763220.014
cell projection assemblyGO:00300311260.014
regulation of cell growthGO:00015581350.014
regulation of multi organism processGO:00439001570.014
response to hypoxiaGO:0001666960.014
regulation of cell morphogenesisGO:00226041530.014
nucleoside monophosphate metabolic processGO:00091231910.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
ketone biosynthetic processGO:0042181170.014
Fly
anterior posterior axis specificationGO:000994820.014
monosaccharide metabolic processGO:0005996740.014
calcium ion homeostasisGO:00550741220.014
intracellular receptor signaling pathwayGO:00305221040.014
9 cis retinoic acid metabolic processGO:004290510.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
negative regulation of proteolysisGO:00458611320.014
positive regulation of organelle organizationGO:00106381950.014
cellular glucuronidationGO:0052695160.014
regulation of actin filament based processGO:00329701410.014
positive regulation of gtpase activityGO:00435471660.014
testosterone biosynthetic processGO:006137020.014
nucleoside monophosphate catabolic processGO:00091251590.014
nucleoside phosphate biosynthetic processGO:19012931090.014
purine containing compound biosynthetic processGO:0072522880.014
response to alcoholGO:0097305640.014
peptide metabolic processGO:0006518510.014
negative regulation of programmed cell deathGO:00430693210.013
tissue regenerationGO:004224630.013
cellular protein catabolic processGO:00442572610.013
regulation of homeostatic processGO:00328441210.013
defense response to fungusGO:005083240.013
blastoderm segmentationGO:000735020.013
negative regulation of organelle organizationGO:00106391260.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
acylglycerol metabolic processGO:0006639270.013
circulatory system developmentGO:00723592620.013
epithelium migrationGO:00901321190.013
regulation of secretionGO:00510461940.013
negative regulation of protein phosphorylationGO:00019331400.013
establishment of protein localization to membraneGO:00901501210.013
glycerophospholipid metabolic processGO:0006650840.013
positive regulation of cell proliferationGO:00082843010.013
negative regulation of cell migrationGO:00303361020.013

CYP3A4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.066
inherited metabolic disorderDOID:6552420.062
sensory system diseaseDOID:00501552030.029
nervous system diseaseDOID:8634310.029
hematopoietic system diseaseDOID:741000.026
immune system diseaseDOID:29141550.026
amino acid metabolic disorderDOID:9252500.022
central nervous system diseaseDOID:3311860.019
cancerDOID:1621670.018
disease of cellular proliferationDOID:145661740.018
cardiovascular system diseaseDOID:12871060.017
Human
organ system cancerDOID:00506861640.016
eye and adnexa diseaseDOID:14921500.015
eye diseaseDOID:56141490.015
musculoskeletal system diseaseDOID:172230.014
retinal diseaseDOID:56791180.013
connective tissue diseaseDOID:651090.013