Homo sapiens

119 known processes

SENP1

SUMO1/sentrin specific peptidase 1

(Aliases: SuPr-2)

SENP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein desumoylationGO:001692640.438
small gtpase mediated signal transductionGO:0007264780.308
microtubule cytoskeleton organizationGO:00002261760.279
microtubule based processGO:00070172100.269
protein import into nucleusGO:00066061040.265
cellular response to dna damage stimulusGO:00069743790.246
multicellular organismal agingGO:001025930.226
Worm
ribonucleoside triphosphate metabolic processGO:00091994120.206
regulation of small gtpase mediated signal transductionGO:00510561560.201
determination of adult lifespanGO:000834020.200
Worm
mitotic cell cycle processGO:19030472860.194
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.193
positive regulation of nucleoside metabolic processGO:00459791860.186
nucleocytoplasmic transportGO:00069131760.171
dna conformation changeGO:00711031130.168
positive regulation of catabolic processGO:00098963100.166
protein localization to organelleGO:00333652800.165
intracellular protein transportGO:00068862700.163
nuclear transportGO:00511691790.162
central nervous system projection neuron axonogenesisGO:002195230.155
Fly
mrna metabolic processGO:00160711750.154
cytoplasmic transportGO:00164823790.139
protein targetingGO:00066051870.135
ras protein signal transductionGO:0007265730.133
positive regulation of protein phosphorylationGO:00019343130.132
nucleoside triphosphate catabolic processGO:00091433940.129
mitotic cell cycleGO:00002783260.127
protein localization to nucleusGO:00345041360.116
purine ribonucleoside triphosphate metabolic processGO:00092054110.113
locomotory behaviorGO:000762610.105
organophosphate catabolic processGO:00464344300.101
nucleus organizationGO:0006997280.099
oxidation reduction processGO:00551143960.094
embryo developmentGO:00097901230.094
Worm
response to abiotic stimulusGO:00096283360.092
Fly
chromatin organizationGO:00063253510.091
purine ribonucleoside metabolic processGO:00461284370.090
nucleotide catabolic processGO:00091664080.090
guanosine containing compound metabolic processGO:19010682440.090
cardiac muscle cell contractionGO:008600340.088
regulation of ras protein signal transductionGO:00465781550.084
ribonucleotide catabolic processGO:00092614050.083
nucleoside triphosphate metabolic processGO:00091414220.083
nucleoside catabolic processGO:00091644080.082
purine nucleotide catabolic processGO:00061954050.080
nuclear importGO:00511701060.080
cellular macromolecule catabolic processGO:00442653800.079
Mouse
regulation of transferase activityGO:00513383550.078
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.078
Mouse
proteolysis involved in cellular protein catabolic processGO:00516032440.077
Mouse
signal transduction by phosphorylationGO:00230142970.077
glycosyl compound catabolic processGO:19016584130.077
spindle organizationGO:0007051530.076
tricarboxylic acid cycleGO:000609940.075
regulation of kinase activityGO:00435493140.075
single organism cellular localizationGO:19025803320.074
positive regulation of cellular catabolic processGO:00313312840.074
cellular component morphogenesisGO:00329893140.073
Fly
regulation of protein localizationGO:00328802960.073
Worm
purine containing compound catabolic processGO:00725234110.073
purine nucleoside triphosphate metabolic processGO:00091444120.072
dna damage checkpointGO:0000077680.072
establishment of protein localization to organelleGO:00725941720.072
positive regulation of purine nucleotide metabolic processGO:19005442270.068
mitotic nuclear divisionGO:00070671190.068
dendritic spine morphogenesisGO:006099730.064
Fly
female gamete generationGO:000729220.064
nucleoside phosphate catabolic processGO:19012924120.063
positive regulation of protein serine threonine kinase activityGO:00719021190.061
regulation of protein kinase activityGO:00458592890.061
central nervous system neuron axonogenesisGO:002195530.060
Fly
post embryonic developmentGO:000979120.059
Fly
purine ribonucleotide catabolic processGO:00091544040.058
anatomical structure homeostasisGO:00602491000.058
protein sumoylationGO:0016925250.057
protein targeting to nucleusGO:00447441040.057
cell projection organizationGO:00300302520.057
Fly
protein modification by small protein removalGO:0070646920.056
mitotic spindle organizationGO:0007052270.055
oogenesisGO:004847720.052
cell part morphogenesisGO:00329901370.051
Fly
negative regulation of bindingGO:0051100570.051
regulation of protein serine threonine kinase activityGO:00719001790.050
positive regulation of nucleotide catabolic processGO:00308131850.049
regulation of gtpase activityGO:00430871800.049
regulation of protein modification by small protein conjugation or removalGO:19033201070.049
nuclear exportGO:0051168690.048
associative learningGO:000830610.048
gtp metabolic processGO:00460392390.047
positive regulation of nucleotide metabolic processGO:00459812300.047
single organism nuclear importGO:19025931040.047
rhythmic behaviorGO:000762220.047
nuclear divisionGO:00002801280.045
pharynx developmentGO:006046510.045
purine ribonucleoside triphosphate catabolic processGO:00092073910.044
positive regulation of map kinase activityGO:0043406800.043
positive regulation of purine nucleotide catabolic processGO:00331231850.043
regulation of angiogenesisGO:0045765920.043
mapk cascadeGO:00001652880.043
gtp catabolic processGO:00061842370.042
positive regulation of transferase activityGO:00513472270.042
regulation of nucleotide metabolic processGO:00061402690.041
response to growth factorGO:00708482050.041
negative regulation of locomotionGO:00400131180.041
regulation of ras gtpase activityGO:00323181280.040
mitotic sister chromatid segregationGO:0000070530.040
protein catabolic processGO:00301633250.039
Mouse
proteasomal protein catabolic processGO:00104981760.039
Mouse
positive regulation of phosphorylationGO:00423273940.038
negative regulation of cellular component movementGO:00512711060.038
actin mediated cell contractionGO:0070252120.038
membrane organizationGO:00610242920.038
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.038
purine nucleoside triphosphate catabolic processGO:00091463920.037
rna phosphodiester bond hydrolysisGO:0090501350.037
ribonucleoside catabolic processGO:00424544060.037
negative regulation of epithelial cell migrationGO:0010633380.037
neuron differentiationGO:00301821380.037
Fly
angiogenesisGO:00015251470.036
organelle fissionGO:00482851490.036
nuclear body organizationGO:003057540.036
dna repairGO:00062811980.036
cell morphogenesisGO:00009022960.036
Fly
ameboidal type cell migrationGO:00016671350.035
histone modificationGO:00165702510.035
regulation of nucleoside metabolic processGO:00091182090.035
neurogenesisGO:00220081690.035
Fly
negative regulation of cell migrationGO:00303361020.035
negative regulation of catalytic activityGO:00430863350.035
chromosome segregationGO:00070591140.035
regulation of cytoplasmic transportGO:19036491490.034
positive regulation of gtp catabolic processGO:00331261660.034
modification dependent protein catabolic processGO:00199412090.034
Mouse
actin filament based processGO:00300292240.033
hemopoiesisGO:00300971800.033
Mouse Fly
regulation of map kinase activityGO:00434051080.033
striated muscle contractionGO:0006941520.033
protein ubiquitinationGO:00165673140.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
regulation of proteasomal protein catabolic processGO:0061136870.032
Mouse
tricarboxylic acid metabolic processGO:007235040.032
cellular response to growth factor stimulusGO:00713631970.032
chromatin assembly or disassemblyGO:0006333780.032
meiotic chromosome segregationGO:004513240.031
maintenance of locationGO:00512351120.031
purine ribonucleoside catabolic processGO:00461303980.031
negative regulation of transportGO:00510511760.030
regulation of cellular response to stressGO:00801352440.030
chromatin modificationGO:00165682980.030
purine nucleoside catabolic processGO:00061523980.029
nucleoside monophosphate metabolic processGO:00091231910.029
macromolecule methylationGO:0043414970.029
regulation of protein transportGO:00512232130.029
regulation of intracellular protein transportGO:00331571230.029
nervous system developmentGO:00073992930.029
Fly
response to transforming growth factor betaGO:0071559940.029
endomembrane system organizationGO:00102561960.028
regulation of purine nucleotide metabolic processGO:19005422640.028
regulation of protein catabolic processGO:00421761550.028
Mouse
cell projection morphogenesisGO:00488581290.028
Fly
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.027
endocytosisGO:00068971590.027
pattern specification processGO:0007389430.027
regulation of anatomical structure morphogenesisGO:00226032860.027
positive regulation of developmental processGO:00510943140.027
regulation of proteolysisGO:00301622930.027
cellular protein catabolic processGO:00442572610.026
Mouse
cellular response to transforming growth factor beta stimulusGO:0071560940.026
biological adhesionGO:00226103310.026
regulation of cellular protein catabolic processGO:1903362960.026
Mouse
negative regulation of multicellular organismal processGO:00512413170.026
Fly
negative regulation of cellular component organizationGO:00511292350.025
ribonucleoprotein complex biogenesisGO:00226131160.025
positive regulation of protein catabolic processGO:0045732750.025
negative regulation of cytoplasmic transportGO:1903650460.025
cardiac muscle contractionGO:0060048340.025
regulation of nucleocytoplasmic transportGO:0046822980.025
blood vessel developmentGO:00015681720.024
positive regulation of kinase activityGO:00336742040.024
regulation of mapk cascadeGO:00434082620.024
regulation of gtp catabolic processGO:00331241800.024
chemical homeostasisGO:00488783060.024
cardiovascular system developmentGO:00723582620.023
positive regulation of transportGO:00510503360.023
dna packagingGO:0006323770.023
neuroblast proliferationGO:000740540.023
dendritic spine organizationGO:009706140.023
Fly
generation of precursor metabolites and energyGO:0006091680.022
protein modification by small protein conjugationGO:00324463420.022
somitogenesisGO:000175620.022
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.022
Mouse
cellular response to endogenous stimulusGO:00714953360.022
positive regulation of gtpase activityGO:00435471660.021
positive regulation of cellular component biogenesisGO:00440891580.021
positive regulation of protein kinase activityGO:00458601900.021
peripheral nervous system developmentGO:000742220.021
rna processingGO:00063962550.021
mitotic cell cycle phase transitionGO:00447721620.021
ubiquitin dependent protein catabolic processGO:00065112060.021
Mouse
central nervous system developmentGO:00074171230.021
Fly
fas signaling pathwayGO:003633730.021
actin filament based movementGO:0030048170.021
cell cycle phase transitionGO:00447701730.021
response to ionizing radiationGO:0010212650.021
response to biotic stimulusGO:00096072760.021
protein importGO:00170381300.021
generation of neuronsGO:00486991520.020
Fly
positive regulation of ras gtpase activityGO:00323201170.020
secretionGO:00469032540.020
central nervous system neuron developmentGO:002195470.020
Fly
positive regulation of cellular component organizationGO:00511303760.020
guanosine containing compound catabolic processGO:19010692390.020
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.020
Mouse
cellular amino acid metabolic processGO:00065201160.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
negative regulation of phosphorus metabolic processGO:00105632670.020
negative regulation of phosphate metabolic processGO:00459362670.020
regulation of cellular ketone metabolic processGO:0010565500.020
cell morphogenesis involved in neuron differentiationGO:0048667440.020
Fly
carbohydrate derivative biosynthetic processGO:19011372070.019
inorganic ion transmembrane transportGO:00986602310.019
regulation of establishment of protein localizationGO:00702012420.019
cation transportGO:00068123310.019
inorganic cation transmembrane transportGO:00986621940.019
multicellular organismal signalingGO:0035637340.019
regulation of purine nucleotide catabolic processGO:00331212050.019
mrna processingGO:00063971330.019
cell morphogenesis involved in differentiationGO:00009041440.019
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
cation transmembrane transportGO:00986552380.018
regulation of cell motilityGO:20001452990.018
divalent metal ion transportGO:00708381520.018
cellular homeostasisGO:00197251960.018
embryonic epithelial tube formationGO:000183840.018
vesicle mediated transportGO:00161923710.018
regulation of cellular component biogenesisGO:00440872810.018
agingGO:0007568660.018
Worm
covalent chromatin modificationGO:00165692540.018
response to external biotic stimulusGO:00432072610.018
negative regulation of dna bindingGO:0043392180.018
neuron developmentGO:00486661130.018
Fly
cell developmentGO:00484683280.017
Fly
tissue migrationGO:00901301190.017
nucleotide biosynthetic processGO:00091651090.017
circadian behaviorGO:004851220.017
regulation of cell morphogenesisGO:00226041530.017
cellular chemical homeostasisGO:00550821800.017
negative regulation of intracellular protein transportGO:0090317420.017
negative regulation of intracellular transportGO:0032387600.017
sister chromatid segregationGO:0000819540.017
morphogenesis of embryonic epitheliumGO:001633140.017
spermatid differentiationGO:004851540.017
positive regulation of proteasomal protein catabolic processGO:1901800350.016
epithelium migrationGO:00901321190.016
carbohydrate metabolic processGO:00059752070.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
histone methylationGO:0016571600.016
regulation of system processGO:00440571010.016
protein methylationGO:0006479740.016
heart contractionGO:0060047620.016
negative regulation of protein modification processGO:00314002000.016
positive regulation of hydrolase activityGO:00513453310.016
regulation of intracellular transportGO:00323861950.016
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.016
digestive system developmentGO:0055123750.016
embryonic placenta developmentGO:000189210.016
regulation of cellular amine metabolic processGO:0033238110.015
transmembrane transportGO:00550853990.015
regulation of cell migrationGO:00303342890.015
visual behaviorGO:000763220.015
ossificationGO:00015031210.015
autophagic cell deathGO:004810230.015
double strand break repairGO:00063021010.015
positive regulation of cellular protein catabolic processGO:1903364370.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
regulation of gene silencingGO:0060968240.015
tube developmentGO:00352951250.015
epithelium developmentGO:00604292270.015
regulation of nucleotide catabolic processGO:00308112050.015
response to other organismGO:00517072610.014
innate immune responseGO:00450871780.014
response to salt stressGO:000965130.014
ribose phosphate biosynthetic processGO:0046390820.014
regulation of cellular amino acid metabolic processGO:000652160.014
regulation of bindingGO:00510981110.014
oocyte developmentGO:004859910.014
protein export from nucleusGO:0006611290.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.013
muscle contractionGO:0006936730.013
regulation of neural precursor cell proliferationGO:200017740.013
centrosome organizationGO:0051297580.013
positive regulation of apoptotic signaling pathwayGO:2001235700.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
Mouse Fly
rna splicingGO:00083801310.013
positive regulation of proteolysisGO:00458621420.013
regulation of cellular component movementGO:00512703340.013
endothelial cell migrationGO:0043542860.013
metal ion transportGO:00300012720.013
negative regulation of cell deathGO:00605483450.013
regulation of dna bindingGO:0051101370.013
atp metabolic processGO:00460341760.013
adult locomotory behaviorGO:000834410.013
modification dependent macromolecule catabolic processGO:00436322120.013
Mouse
blood circulationGO:00080151130.013
rna interferenceGO:001624640.013
blood vessel morphogenesisGO:00485141620.013
segmentationGO:003528240.013
regulation of muscle contractionGO:0006937450.013
definitive hemopoiesisGO:006021620.013
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.012
mitochondrion organizationGO:00070051560.012
positive regulation of protein complex assemblyGO:0031334860.012
regulation of cell developmentGO:00602841610.012
single organism carbohydrate metabolic processGO:00447231930.012
response to fungusGO:000962040.012
dephosphorylationGO:00163112090.012
negative regulation of nucleocytoplasmic transportGO:0046823370.012
response to oxidative stressGO:00069791210.012
axonogenesisGO:0007409310.012
Fly
negative regulation of cell motilityGO:20001461040.012
peptidyl lysine acetylationGO:00183941010.012
response to hypoxiaGO:0001666960.012
Fly
head developmentGO:00603221080.012
circulatory system developmentGO:00723592620.012
regulation of protein targetingGO:1903533910.012
neuron projection morphogenesisGO:0048812500.012
Fly
neural crest cell developmentGO:001403230.012
regulation of actin filament based processGO:00329701410.012
system processGO:00030083490.012
secretion by cellGO:00329402260.012
lipid storageGO:0019915280.012
positive regulation of programmed cell deathGO:00430682490.011
cellular respirationGO:0045333210.011
response to oxygen containing compoundGO:19017003690.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
spermatid developmentGO:000728640.011
regulation of protein ubiquitinationGO:0031396950.011
phagocytosisGO:0006909420.011
regulation of mitotic cell cycleGO:00073461890.011
organophosphate biosynthetic processGO:00904071630.011
smad protein import into nucleusGO:0007184130.011
regulation of cell differentiationGO:00455953930.011
Mouse Fly
short term memoryGO:000761410.011
regulation of body fluid levelsGO:0050878990.011
positive regulation of neural precursor cell proliferationGO:200017920.011
regulation of immune responseGO:00507762010.011
heart processGO:0003015620.011
negative regulation of protein transportGO:0051224750.011
defense response to fungusGO:005083240.011
embryo development ending in birth or egg hatchingGO:0009792340.011
Worm
regulation of apoptotic signaling pathwayGO:20012331750.011
glucose homeostasisGO:0042593310.011
positive regulation of protein ubiquitinationGO:0031398530.011
regulation of blood circulationGO:1903522590.011
wnt signaling pathwayGO:00160551560.011
positive regulation of defense responseGO:0031349870.011
compound eye developmentGO:004874910.011
dna recombinationGO:0006310770.011
cell adhesionGO:00071553250.010
regulation of metal ion transportGO:00109591200.010
amine metabolic processGO:0009308440.010
cellular ketone metabolic processGO:0042180800.010
cilium morphogenesisGO:0060271750.010
osteoblast differentiationGO:0001649920.010
cellular protein complex assemblyGO:00436231880.010
negative regulation of developmental processGO:00510932470.010
Fly
organelle localizationGO:0051640840.010
response to hormoneGO:00097251750.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
immune responseGO:00069553070.010
embryonic camera type eye developmentGO:003107620.010
nucleoside monophosphate catabolic processGO:00091251590.010
regulation of muscle cell differentiationGO:0051147310.010
purine nucleoside monophosphate catabolic processGO:00091281580.010

SENP1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.028
nervous system diseaseDOID:8634310.028
eye and adnexa diseaseDOID:14921500.028
physical disorderDOID:0080015410.013
central nervous system diseaseDOID:3311860.012
cancerDOID:1621670.010
organ system cancerDOID:00506861640.010
disease of cellular proliferationDOID:145661740.010