Homo sapiens

0 known processes

NOTUM

notum pectinacetylesterase homolog (Drosophila)

NOTUM biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.089
regulation of cellular ketone metabolic processGO:0010565500.086
regulation of cell differentiationGO:00455953930.074
cellular amino acid metabolic processGO:00065201160.068
anatomical structure formation involved in morphogenesisGO:00486462840.067
cellular ketone metabolic processGO:0042180800.065
organ morphogenesisGO:00098871470.065
regulation of cell cycleGO:00517263930.060
epithelium developmentGO:00604292270.060
regulation of locomotionGO:00400123290.059
regulation of cellular amine metabolic processGO:0033238110.058
nervous system developmentGO:00073992930.057
segmentationGO:003528240.057
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.056
amine metabolic processGO:0009308440.052
regulation of anatomical structure morphogenesisGO:00226032860.052
regulation of cell migrationGO:00303342890.051
enzyme linked receptor protein signaling pathwayGO:00071673030.048
positive regulation of cell proliferationGO:00082843010.048
regulation of cellular component movementGO:00512703340.047
cell developmentGO:00484683280.046
regulation of cellular amino acid metabolic processGO:000652160.045
positive regulation of cellular amino acid metabolic processGO:004576430.045
hematopoietic or lymphoid organ developmentGO:00485341860.043
cellular amine metabolic processGO:0044106410.043
multicellular organismal agingGO:001025930.042
actin filament based processGO:00300292240.042
membrane organizationGO:00610242920.042
positive regulation of cellular amine metabolic processGO:003324070.041
cardiovascular system developmentGO:00723582620.041
mitotic cell cycleGO:00002783260.041
determination of adult lifespanGO:000834020.040
cytoplasmic transportGO:00164823790.040
cell morphogenesisGO:00009022960.039
locomotory behaviorGO:000762610.038
negative regulation of multicellular organismal processGO:00512413170.038
wnt signaling pathwayGO:00160551560.038
forebrain regionalizationGO:002187130.038
hindbrain developmentGO:003090230.037
negative regulation of developmental processGO:00510932470.037
positive regulation of developmental processGO:00510943140.037
regulation of canonical wnt signaling pathwayGO:0060828880.037
regulation of cell motilityGO:20001452990.036
negative regulation of cell deathGO:00605483450.036
response to oxygen containing compoundGO:19017003690.036
female gamete generationGO:000729220.036
embryonic morphogenesisGO:0048598850.035
negative regulation of protein metabolic processGO:00512483910.035
oogenesisGO:004847720.035
negative regulation of cell proliferationGO:00082852280.034
immune system developmentGO:00025201950.034
cellular response to endogenous stimulusGO:00714953360.034
protein maturationGO:00516042330.034
negative regulation of apoptotic processGO:00430663160.034
negative regulation of programmed cell deathGO:00430693210.034
positive regulation of phosphorylationGO:00423273940.033
circulatory system developmentGO:00723592620.033
negative regulation of cell differentiationGO:00455961710.033
lipid metabolic processGO:00066293810.033
organ formationGO:004864530.032
tube developmentGO:00352951250.032
single organism cellular localizationGO:19025803320.032
protein catabolic processGO:00301633250.032
positive regulation of cellular component organizationGO:00511303760.032
cellular macromolecule catabolic processGO:00442653800.032
chemical homeostasisGO:00488783060.032
cellular component morphogenesisGO:00329893140.032
cell adhesionGO:00071553250.031
positive regulation of cell differentiationGO:00455972110.031
cellular response to dna damage stimulusGO:00069743790.030
biological adhesionGO:00226103310.030
small molecule biosynthetic processGO:00442831570.030
ras protein signal transductionGO:0007265730.030
regulation of protein localizationGO:00328802960.029
regulation of wnt signaling pathwayGO:00301111230.029
regulation of cellular response to stressGO:00801352440.029
negative regulation of cellular protein metabolic processGO:00322693530.029
positive regulation of catabolic processGO:00098963100.029
blastoderm segmentationGO:000735020.029
regulation of transferase activityGO:00513383550.029
pituitary gland developmentGO:002198320.029
negative regulation of catalytic activityGO:00430863350.028
brain developmentGO:0007420970.028
negative regulation of phosphorus metabolic processGO:00105632670.028
embryonic forelimb morphogenesisGO:003511540.028
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.028
intracellular protein transportGO:00068862700.028
protein processingGO:00164852260.027
blood vessel developmentGO:00015681720.027
hemopoiesisGO:00300971800.027
spinal cord developmentGO:002151040.027
vasculature developmentGO:00019441810.026
nucleoside triphosphate catabolic processGO:00091433940.026
central nervous system developmentGO:00074171230.026
cell projection organizationGO:00300302520.026
canonical wnt signaling pathwayGO:00600701160.026
tissue morphogenesisGO:0048729960.026
forelimb morphogenesisGO:003513640.026
negative regulation of cellular component organizationGO:00511292350.025
protein localization to organelleGO:00333652800.025
blood vessel morphogenesisGO:00485141620.025
organophosphate catabolic processGO:00464344300.025
positive regulation of protein phosphorylationGO:00019343130.025
positive regulation of cellular catabolic processGO:00313312840.025
neuron fate commitmentGO:004866320.025
cell fate determinationGO:000170930.025
inner ear morphogenesisGO:004247240.025
regulation of establishment of protein localizationGO:00702012420.025
positive regulation of tooth mineralizationGO:007017220.025
somitogenesisGO:000175620.025
actin filament based movementGO:0030048170.025
single organism membrane organizationGO:00448022680.024
epidermis morphogenesisGO:004873030.024
skeletal system developmentGO:0001501790.024
endomembrane system organizationGO:00102561960.024
small gtpase mediated signal transductionGO:0007264780.024
regulation of cell cycle processGO:00105642660.024
response to abiotic stimulusGO:00096283360.024
positive regulation of apoptotic processGO:00430652460.024
nucleoside triphosphate metabolic processGO:00091414220.024
system processGO:00030083490.024
immune responseGO:00069553070.024
positive regulation of programmed cell deathGO:00430682490.023
purine containing compound catabolic processGO:00725234110.023
generation of neuronsGO:00486991520.023
regulation of proteolysisGO:00301622930.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
reactive oxygen species metabolic processGO:0072593750.023
regulation of kinase activityGO:00435493140.023
cellular protein catabolic processGO:00442572610.023
mitotic cell cycle processGO:19030472860.023
signal transduction by phosphorylationGO:00230142970.022
regulation of cell developmentGO:00602841610.022
actin cytoskeleton organizationGO:00300362070.022
cellular lipid metabolic processGO:00442553030.022
positive regulation of cell deathGO:00109422630.022
purine ribonucleoside metabolic processGO:00461284370.022
positive regulation of hydrolase activityGO:00513453310.022
positive regulation of transferase activityGO:00513472270.022
posttranscriptional regulation of gene expressionGO:00106082130.022
neurogenesisGO:00220081690.022
sex determinationGO:000753030.022
cell differentiation in spinal cordGO:002151510.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
negative regulation of cellular component movementGO:00512711060.021
positive regulation of odontogenesisGO:004248230.021
head developmentGO:00603221080.021
chromatin modificationGO:00165682980.021
negative regulation of protein modification processGO:00314002000.021
anterior posterior axis specificationGO:000994820.021
positive regulation of immune system processGO:00026842830.021
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.021
response to external biotic stimulusGO:00432072610.021
organic hydroxy compound metabolic processGO:19016151470.021
response to biotic stimulusGO:00096072760.021
mapk cascadeGO:00001652880.021
epithelial cell differentiationGO:00308551410.021
positive regulation of cellular component movementGO:00512721810.021
mesenchyme developmentGO:0060485590.021
carbohydrate metabolic processGO:00059752070.021
positive regulation of cell motilityGO:20001471770.021
regulation of protein transportGO:00512232130.021
protein targetingGO:00066051870.021
embryo developmentGO:00097901230.020
chromatin organizationGO:00063253510.020
cytokine productionGO:00018162470.020
cellular response to growth factor stimulusGO:00713631970.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
cellular macromolecular complex assemblyGO:00346223240.020
nuclear transportGO:00511691790.020
negative regulation of cell cycleGO:00457861930.020
purine nucleotide catabolic processGO:00061954050.020
nucleoside catabolic processGO:00091644080.020
regulation of growthGO:00400081650.020
nucleoside phosphate catabolic processGO:19012924120.020
glycosyl compound catabolic processGO:19016584130.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.020
ribonucleotide catabolic processGO:00092614050.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
morphogenesis of embryonic epitheliumGO:001633140.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
neuron differentiationGO:00301821380.020
regulation of cytokine productionGO:00018172320.020
specification of organ identityGO:001009230.020
cell growthGO:00160491600.020
regulation of protein kinase activityGO:00458592890.020
ribonucleoside catabolic processGO:00424544060.020
regulation of hormone levelsGO:00108171250.020
negative regulation of cellular amino acid metabolic processGO:004576320.019
vesicle mediated transportGO:00161923710.019
protein localization to membraneGO:00726571600.019
monocarboxylic acid metabolic processGO:00327871850.019
regulation of cellular component biogenesisGO:00440872810.019
positive regulation of aldosterone metabolic processGO:003234620.019
cellular response to oxygen containing compoundGO:19017012760.019
nucleotide catabolic processGO:00091664080.019
growthGO:00400072020.019
defense responseGO:00069523150.019
negative regulation of phosphate metabolic processGO:00459362670.019
apoptotic signaling pathwayGO:00971902680.019
adult locomotory behaviorGO:000834410.019
regenerationGO:003109940.019
transmembrane transportGO:00550853990.019
regulation of intracellular transportGO:00323861950.019
negative regulation of cellular amine metabolic processGO:003323930.019
negative regulation of locomotionGO:00400131180.019
positive regulation of transportGO:00510503360.019
glycoprotein metabolic processGO:00091001100.018
regulation of mitotic cell cycleGO:00073461890.018
cardiac muscle cell contractionGO:008600340.018
matingGO:000761810.018
cell activationGO:00017752130.018
response to lipidGO:00339932060.018
spermatid differentiationGO:004851540.018
regulation of neural precursor cell proliferationGO:200017740.018
cell cell signalingGO:00072671550.018
lipid biosynthetic processGO:00086101770.018
compound eye developmentGO:004874910.018
positive regulation of cell cycleGO:00457871400.018
purine nucleoside catabolic processGO:00061523980.018
negative regulation of cell migrationGO:00303361020.018
single organism cell adhesionGO:00986021790.018
neuromuscular junction developmentGO:000752830.018
cellular response to cytokine stimulusGO:00713451810.018
cell proliferation in forebrainGO:002184610.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
oxidation reduction processGO:00551143960.018
protein modification by small protein conjugationGO:00324463420.018
cell morphogenesis involved in differentiationGO:00009041440.017
single organism carbohydrate metabolic processGO:00447231930.017
ribonucleoside triphosphate metabolic processGO:00091994120.017
cellular cation homeostasisGO:00300031630.017
regulation of protein maturationGO:19033171500.017
negative regulation of intracellular signal transductionGO:19025321830.017
secretion by cellGO:00329402260.017
dephosphorylationGO:00163112090.017
alcohol metabolic processGO:00060661140.017
regulation of mapk cascadeGO:00434082620.017
peripheral nervous system developmentGO:000742220.017
regulation of endopeptidase activityGO:00525481700.017
regulation of reactive oxygen species metabolic processGO:2000377410.017
carbohydrate derivative biosynthetic processGO:19011372070.017
nucleocytoplasmic transportGO:00069131760.017
protein ubiquitinationGO:00165673140.017
ameboidal type cell migrationGO:00016671350.017
microtubule based processGO:00070172100.017
positive regulation of organelle organizationGO:00106381950.017
motor neuron axon guidanceGO:000804520.017
metencephalon developmentGO:002203720.017
negative regulation of phosphorylationGO:00423261740.017
negative regulation of transportGO:00510511760.017
positive regulation of cell migrationGO:00303351720.017
paramesonephric duct developmentGO:006120520.017
spermatid developmentGO:000728640.017
somatic stem cell maintenanceGO:003501940.017
positive regulation of locomotionGO:00400171860.017
angiogenesisGO:00015251470.016
histone modificationGO:00165702510.016
cation transmembrane transportGO:00986552380.016
negative regulation of testosterone biosynthetic processGO:200022510.016
response to cytokineGO:00340972320.016
regulation of cell adhesionGO:00301551660.016
hair follicle morphogenesisGO:003106920.016
positive regulation of glucocorticoid biosynthetic processGO:003194810.016
organonitrogen compound biosynthetic processGO:19015662000.016
heart developmentGO:0007507950.016
regulation of cell growthGO:00015581350.016
regulation of nucleotide metabolic processGO:00061402690.016
response to woundingGO:00096111680.016
modification dependent protein catabolic processGO:00199412090.016
regulation of response to external stimulusGO:00321012220.016
ubiquitin dependent protein catabolic processGO:00065112060.016
cell projection morphogenesisGO:00488581290.016
purine ribonucleotide catabolic processGO:00091544040.016
plasma membrane organizationGO:00070091150.016
muscle structure developmentGO:0061061980.016
positive regulation of glucocorticoid metabolic processGO:003194510.016
regulation of immune responseGO:00507762010.016
establishment of protein localization to membraneGO:00901501210.016
positive regulation of kinase activityGO:00336742040.016
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.016
regulation of protein processingGO:00706131500.016
regulation of cytoplasmic transportGO:19036491490.016
positive regulation of protein kinase activityGO:00458601900.015
protein localization to plasma membraneGO:0072659930.015
nerve developmentGO:002167540.015
actin mediated cell contractionGO:0070252120.015
rho protein signal transductionGO:0007266260.015
mesonephric duct developmentGO:007217730.015
cranial nerve developmentGO:002154540.015
regulation of dna metabolic processGO:00510521530.015
regulation of intracellular protein transportGO:00331571230.015
cell cycle phase transitionGO:00447701730.015
stem cell differentiationGO:0048863930.015
hormone metabolic processGO:0042445610.015
positive regulation of cell developmentGO:0010720920.015
tube morphogenesisGO:0035239950.015
cell substrate adhesionGO:00315891320.015
regulation of apoptotic signaling pathwayGO:20012331750.015
aortic valve developmentGO:000317630.015
epithelium migrationGO:00901321190.015
ion homeostasisGO:00508012300.015
modification dependent macromolecule catabolic processGO:00436322120.015
cerebellum developmentGO:002154920.015
guanosine containing compound catabolic processGO:19010692390.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of cell morphogenesisGO:00226041530.015
proteasomal protein catabolic processGO:00104981760.015
photoreceptor cell differentiationGO:004653020.015
regulation of stem cell differentiationGO:2000736560.015
embryonic camera type eye developmentGO:003107620.015
establishment of protein localization to organelleGO:00725941720.015
anterior posterior axis specification embryoGO:000859520.015
neurotransmitter secretionGO:000726940.015
single organism reproductive processGO:0044702980.015
covalent chromatin modificationGO:00165692540.014
rna processingGO:00063962550.014
cardiac cell fate determinationGO:006091330.014
carboxylic acid biosynthetic processGO:0046394970.014
regulation of vasculature developmentGO:1901342970.014
secretionGO:00469032540.014
thymus developmentGO:004853830.014
purine ribonucleoside catabolic processGO:00461303980.014
cell part morphogenesisGO:00329901370.014
negative regulation of protein maturationGO:19033181420.014
morphogenesis of a polarized epitheliumGO:000173830.014
cellular protein complex assemblyGO:00436231880.014
negative regulation of protein phosphorylationGO:00019331400.014
sulfur compound metabolic processGO:00067901010.014
negative regulation of hydrolase activityGO:00513461820.014
positive regulation of cortisol biosynthetic processGO:200006610.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
regulation of protein catabolic processGO:00421761550.014
negative regulation of cell motilityGO:20001461040.014
negative regulation of proteolysisGO:00458611320.014
regulation of testosterone biosynthetic processGO:200022420.014
regulation of cytoskeleton organizationGO:00514931770.014
hindlimb morphogenesisGO:003513720.014
positive regulation of cellular component biogenesisGO:00440891580.014
negative regulation of wnt signaling pathwayGO:0030178690.014
mitotic cell cycle phase transitionGO:00447721620.014
protein localization to nucleusGO:00345041360.014
neuroblast proliferationGO:000740540.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
cellular homeostasisGO:00197251960.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regionalizationGO:0003002290.014
organic acid biosynthetic processGO:0016053970.014
microtubule cytoskeleton organizationGO:00002261760.014
embryonic epithelial tube formationGO:000183840.014
memoryGO:000761330.014
establishment or maintenance of bipolar cell polarityGO:006124520.014
positive regulation of neural precursor cell proliferationGO:200017920.014
epithelial cell proliferationGO:00506731280.014
cellular amide metabolic processGO:0043603690.013
epidermis developmentGO:0008544590.013
urogenital system developmentGO:0001655650.013
positive regulation of hormone biosynthetic processGO:004688640.013
cellular response to lipidGO:00713961270.013
syncytium formation by plasma membrane fusionGO:000076820.013
neuroendocrine cell differentiationGO:006110120.013
peptidyl tyrosine phosphorylationGO:00181081700.013
oocyte developmentGO:004859910.013
reproductive processGO:00224141060.013
organelle assemblyGO:00709251760.013
positive regulation of mapk cascadeGO:00434101900.013
testosterone biosynthetic processGO:006137020.013
negative regulation of protein processingGO:00109551420.013
negative regulation of growthGO:0045926970.013
regulation of secretionGO:00510461940.013
single organismal cell cell adhesionGO:00163371480.013
stem cell developmentGO:0048864690.013
epithelial cell migrationGO:00106311190.013
nitrogen compound transportGO:00717051910.013
cell fate commitment involved in pattern specificationGO:006058110.013
ventral spinal cord developmentGO:002151710.013
heart formationGO:006091420.013
digestive tract developmentGO:0048565750.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
cation homeostasisGO:00550801890.013
mesenchymal cell developmentGO:0014031500.013
response to other organismGO:00517072610.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.013
positive regulation of nucleotide metabolic processGO:00459812300.013
tissue migrationGO:00901301190.013
cell divisionGO:00513011680.013
tissue regenerationGO:004224630.013
negative regulation of cell growthGO:0030308830.013
regulation of protein serine threonine kinase activityGO:00719001790.013
actin filament organizationGO:00070151280.013
negative regulation of canonical wnt signaling pathwayGO:0090090550.013
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
associative learningGO:000830610.013
reactive nitrogen species metabolic processGO:200105730.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
fatty acid metabolic processGO:00066311150.013
guanosine containing compound metabolic processGO:19010682440.013
regulation of secretion by cellGO:19035301770.013
positive regulation of cytokine productionGO:00018191670.012
regulation of cell projection organizationGO:00313441070.012
metal ion transportGO:00300012720.012
regulation of epithelial cell migrationGO:0010632930.012
dna repairGO:00062811980.012
positive regulation of nucleoside metabolic processGO:00459791860.012
maintenance of locationGO:00512351120.012
positive regulation of cardioblast differentiationGO:005189120.012
oxidative stress induced premature senescenceGO:009040330.012
limbic system developmentGO:002176130.012
myeloid cell differentiationGO:00300991170.012
convergent extensionGO:006002610.012
tripartite regional subdivisionGO:000735120.012
regulation of purine nucleotide metabolic processGO:19005422640.012
regulation of cardiac muscle tissue growthGO:005502140.012
metal ion homeostasisGO:00550651690.012
neural tube formationGO:000184130.012
peptidyl tyrosine modificationGO:00182121700.012
primary neural tube formationGO:001402030.012
renal system developmentGO:0072001630.012
regulation of nucleotide catabolic processGO:00308112050.012
cellular chemical homeostasisGO:00550821800.012
regulation of homeostatic processGO:00328441210.012
myoblast fusionGO:000752010.012
digestive system developmentGO:0055123750.012
ion transmembrane transportGO:00342203380.012
immune effector processGO:00022521590.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of nucleoside metabolic processGO:00091182090.012
response to growth factorGO:00708482050.012
striated muscle contractionGO:0006941520.012
negative regulation of gliogenesisGO:001401430.012
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.012
follicle stimulating hormone secretionGO:004688430.012
regulation of peptidase activityGO:00525471800.012
negative regulation of immune system processGO:00026831360.012
regulation of response to dna damage stimulusGO:2001020940.012
organic hydroxy compound biosynthetic processGO:1901617710.012
regulation of response to woundingGO:19030341010.012
regulation of multi organism processGO:00439001570.012
leukocyte activationGO:00453211640.012
negative regulation of cell cycle processGO:00109481210.012
response to axon injuryGO:004867810.012
regulation of protein stabilityGO:0031647870.012
regulation of odontogenesisGO:004248140.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
outflow tract septum morphogenesisGO:000314840.012
neuron developmentGO:00486661130.012
dermatome developmentGO:006105430.012
gtp metabolic processGO:00460392390.012
tube closureGO:006060630.012
regulation of cell morphogenesis involved in differentiationGO:0010769830.012
regulation of purine nucleotide catabolic processGO:00331212050.012
protein acylationGO:00435431380.012
negative regulation of transferase activityGO:00513481240.012
rhythmic behaviorGO:000762220.012
neuron projection developmentGO:00311751060.012
mesodermal cell fate commitmentGO:000171020.012
oocyte differentiationGO:000999420.011
male genitalia developmentGO:003053910.011
regulation of body fluid levelsGO:0050878990.011
innate immune responseGO:00450871780.011
sensory organ developmentGO:0007423520.011
regulation of cell cell adhesionGO:0022407570.011
establishment of protein localization to plasma membraneGO:0090002680.011
wound healingGO:00420601150.011
cell projection assemblyGO:00300311260.011
regulation of cell cycle phase transitionGO:19019871260.011
axis elongationGO:000340140.011
leukocyte differentiationGO:0002521980.011
regulation of male gonad developmentGO:200001840.011
t cell differentiation in thymusGO:003307740.011
cellular component disassemblyGO:0022411920.011
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.011
regulation of protein complex assemblyGO:00432541470.011
regulation of membrane potentialGO:0042391950.011
forebrain generation of neuronsGO:002187230.011

NOTUM disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.028
disease of metabolismDOID:00146672950.024
immune system diseaseDOID:29141550.020
sensory system diseaseDOID:00501552030.019
nervous system diseaseDOID:8634310.019
eye diseaseDOID:56141490.017
eye and adnexa diseaseDOID:14921500.017
disease of cellular proliferationDOID:145661740.017
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.016
organ system cancerDOID:00506861640.016
cancerDOID:1621670.016
retinal diseaseDOID:56791180.014
cardiovascular system diseaseDOID:12871060.014
inherited metabolic disorderDOID:6552420.014
central nervous system diseaseDOID:3311860.012