Homo sapiens

0 known processes

CLCN3

chloride channel 3

(Aliases: CLC3,ClC-3)

CLCN3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cardiac muscle cell contractionGO:008600340.755
sodium ion transmembrane transportGO:0035725590.670
inorganic cation transmembrane transportGO:00986621940.612
muscle contractionGO:0006936730.596
cardiac muscle contractionGO:0060048340.591
ion transmembrane transportGO:00342203380.569
Human Rat
inorganic anion transmembrane transportGO:0098661470.551
Human Rat
bicarbonate transportGO:001570160.529
monovalent inorganic cation transportGO:00156721280.503
sodium ion transportGO:0006814610.449
cellular ketone metabolic processGO:0042180800.432
regulation of cellular component movementGO:00512703340.412
actin filament based movementGO:0030048170.406
regulation of ion transmembrane transportGO:00347651320.405
Rat
blood circulationGO:00080151130.402
cellular amino acid metabolic processGO:00065201160.397
regulation of cellular amino acid metabolic processGO:000652160.397
regulation of ventricular cardiac muscle cell membrane repolarizationGO:0060307100.385
cation transportGO:00068123310.384
negative regulation of cellular amine metabolic processGO:003323930.370
regulation of cellular ketone metabolic processGO:0010565500.365
regulation of cellular amine metabolic processGO:0033238110.337
regulation of cardiac muscle contractionGO:0055117330.320
regulation of cardiac muscle cell contractionGO:0086004230.314
protein nitrosylationGO:001701410.314
cation transmembrane transportGO:00986552380.301
amine metabolic processGO:0009308440.289
transmembrane transportGO:00550853990.286
Human Rat
membrane hyperpolarizationGO:006008110.276
circulatory system processGO:00030131130.264
spermatid developmentGO:000728640.258
muscle system processGO:0003012810.247
spermatid differentiationGO:004851540.247
cardiac muscle cell action potentialGO:0086001230.222
regulation of actin filament based processGO:00329701410.219
system processGO:00030083490.206
ion homeostasisGO:00508012300.203
protein localization to plasma membraneGO:0072659930.202
endosomal transportGO:00161971290.202
regulation of ion transportGO:00432691890.193
Rat
nucleoside catabolic processGO:00091644080.191
cardiac muscle cell action potential involved in contractionGO:0086002210.181
regulation of membrane potentialGO:0042391950.174
inorganic ion transmembrane transportGO:00986602310.170
Human Rat
metal ion transportGO:00300012720.167
regulation of sodium ion transmembrane transportGO:1902305230.163
regulation of transmembrane transportGO:00347621390.158
Rat
negative regulation of cellular amino acid metabolic processGO:004576320.157
negative regulation of cellular protein metabolic processGO:00322693530.151
action potentialGO:0001508340.143
striated muscle contractionGO:0006941520.137
negative regulation of peptidyl cysteine s nitrosylationGO:190208310.132
regulation of establishment of protein localizationGO:00702012420.130
regulation of actin filament based movementGO:1903115240.129
regulation of purine nucleotide metabolic processGO:19005422640.128
secretionGO:00469032540.126
actin mediated cell contractionGO:0070252120.125
regulation of muscle system processGO:0090257530.125
purine ribonucleoside triphosphate catabolic processGO:00092073910.124
purine ribonucleoside metabolic processGO:00461284370.123
regulation of muscle contractionGO:0006937450.120
cell developmentGO:00484683280.118
lipid localizationGO:00108761060.117
regulation of blood circulationGO:1903522590.116
regulation of heart rateGO:0002027380.113
negative regulation of protein metabolic processGO:00512483910.110
plasma membrane organizationGO:00070091150.109
single organism cellular localizationGO:19025803320.109
purine ribonucleotide catabolic processGO:00091544040.108
purine ribonucleoside catabolic processGO:00461303980.107
nucleotide catabolic processGO:00091664080.106
ribonucleoside catabolic processGO:00424544060.103
peptidyl cysteine s nitrosylationGO:001811910.101
endomembrane system organizationGO:00102561960.099
glycosyl compound catabolic processGO:19016584130.099
positive regulation of cellular component organizationGO:00511303760.098
ribonucleoside triphosphate catabolic processGO:00092033910.096
purine nucleoside triphosphate catabolic processGO:00091463920.095
membrane repolarizationGO:0086009230.094
ribonucleotide catabolic processGO:00092614050.094
gtp metabolic processGO:00460392390.093
protein homooligomerizationGO:00512601000.091
membrane organizationGO:00610242920.089
Mouse
rab protein signal transductionGO:003248240.088
negative regulation of phosphorus metabolic processGO:00105632670.088
ribonucleoside triphosphate metabolic processGO:00091994120.088
negative regulation of protein modification processGO:00314002000.087
nucleoside triphosphate metabolic processGO:00091414220.087
cellular homeostasisGO:00197251960.086
transepithelial transportGO:007063390.086
regulation of anion channel activityGO:001035920.085
purine nucleoside triphosphate metabolic processGO:00091444120.082
positive regulation of transportGO:00510503360.081
regulation of striated muscle contractionGO:0006942370.080
regulation of membrane repolarizationGO:0060306160.079
positive regulation of purine nucleotide catabolic processGO:00331231850.078
chloride transportGO:0006821410.077
Human Rat
chemical homeostasisGO:00488783060.076
protein ubiquitinationGO:00165673140.075
regulation of metal ion transportGO:00109591200.075
regulation of sodium ion transportGO:0002028240.073
peptidyl cysteine modificationGO:001819890.073
regulation of vasodilationGO:004231240.072
cation homeostasisGO:00550801890.070
positive regulation of vasodilationGO:004590940.070
protein modification by small protein conjugationGO:00324463420.070
female gamete generationGO:000729220.069
nucleoside phosphate catabolic processGO:19012924120.065
regulation of gtpase activityGO:00430871800.064
regulation of anion transportGO:0044070250.063
Rat
gtp catabolic processGO:00061842370.062
positive regulation of catabolic processGO:00098963100.061
post embryonic developmentGO:000979120.060
purine ribonucleoside triphosphate metabolic processGO:00092054110.059
golgi vesicle transportGO:0048193800.059
establishment of protein localization to plasma membraneGO:0090002680.058
regulation of cyclase activityGO:0031279190.058
regulation of protein transportGO:00512232130.058
vesicle mediated transportGO:00161923710.057
Mouse
purine nucleotide catabolic processGO:00061954050.057
purine containing compound catabolic processGO:00725234110.057
positive regulation of nucleotide metabolic processGO:00459812300.056
modified amino acid transportGO:0072337110.056
positive regulation of gtpase activityGO:00435471660.055
regulation of guanylate cyclase activityGO:003128220.054
establishment of protein localization to membraneGO:00901501210.054
regulation of cell cycleGO:00517263930.054
protein oligomerizationGO:00512591730.054
response to other organismGO:00517072610.053
regulation of protein localizationGO:00328802960.053
organophosphate catabolic processGO:00464344300.053
ras protein signal transductionGO:0007265730.053
positive regulation of cellular catabolic processGO:00313312840.053
heart contractionGO:0060047620.052
reproductive processGO:00224141060.051
oogenesisGO:004847720.051
post golgi vesicle mediated transportGO:0006892360.051
single organism reproductive processGO:0044702980.050
positive regulation of transmembrane transportGO:0034764410.050
negative regulation of phosphorylationGO:00423261740.050
guanosine containing compound catabolic processGO:19010692390.048
monovalent inorganic cation homeostasisGO:0055067370.048
regulation of intracellular transportGO:00323861950.046
regulation of growthGO:00400081650.046
protein localization to membraneGO:00726571600.045
regulation of cell adhesionGO:00301551660.045
organ morphogenesisGO:00098871470.045
amino acid betaine transportGO:001583840.044
actin filament based processGO:00300292240.044
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.044
apoptotic signaling pathwayGO:00971902680.044
regulation of purine nucleotide catabolic processGO:00331212050.043
regulation of transporter activityGO:0032409820.042
neuromuscular junction developmentGO:000752830.042
heart processGO:0003015620.042
oocyte developmentGO:004859910.041
protein k48 linked ubiquitinationGO:0070936380.041
regulation of heart contractionGO:0008016500.040
multicellular organismal agingGO:001025930.040
single organism membrane organizationGO:00448022680.038
positive regulation of protein transportGO:00512221350.037
positive regulation of gtp catabolic processGO:00331261660.037
cellular component morphogenesisGO:00329893140.036
guanosine containing compound metabolic processGO:19010682440.035
purine nucleoside catabolic processGO:00061523980.035
cellular cation homeostasisGO:00300031630.035
regulation of response to external stimulusGO:00321012220.035
positive regulation of nucleoside metabolic processGO:00459791860.035
locomotory behaviorGO:000762610.035
positive regulation of rab gtpase activityGO:0032851390.034
response to abiotic stimulusGO:00096283360.034
cytoplasmic transportGO:00164823790.034
carbohydrate derivative biosynthetic processGO:19011372070.033
regulation of intracellular protein transportGO:00331571230.033
positive regulation of ras gtpase activityGO:00323201170.033
nucleoside triphosphate catabolic processGO:00091433940.033
behaviorGO:00076101120.033
immune responseGO:00069553070.033
defense responseGO:00069523150.033
regulation of intracellular phGO:0051453160.032
nucleus organizationGO:0006997280.032
divalent inorganic cation homeostasisGO:00725071360.032
microtubule based processGO:00070172100.032
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.031
determination of adult lifespanGO:000834020.031
nervous system developmentGO:00073992930.031
intracellular protein transportGO:00068862700.031
cellular ion homeostasisGO:00068731680.030
renal sodium ion transportGO:000309620.030
negative regulation of cell proliferationGO:00082852280.030
response to oxygen containing compoundGO:19017003690.029
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.029
regulation of ras gtpase activityGO:00323181280.029
maintenance of locationGO:00512351120.029
signal transduction by phosphorylationGO:00230142970.028
small gtpase mediated signal transductionGO:0007264780.028
ribonucleotide biosynthetic processGO:0009260810.028
renal absorptionGO:007029360.028
positive regulation of ion transmembrane transportGO:0034767400.028
organelle localizationGO:0051640840.028
response to hormoneGO:00097251750.028
regulation of protein localization to plasma membraneGO:1903076400.027
inner ear morphogenesisGO:004247240.027
memoryGO:000761330.027
vesicle organizationGO:0016050620.026
negative regulation of cyclic nucleotide biosynthetic processGO:0030803100.026
proteolysis involved in cellular protein catabolic processGO:00516032440.026
regulation of chloride transportGO:200122520.026
protein localization to organelleGO:00333652800.026
positive regulation of protein targeting to membraneGO:009031480.026
growthGO:00400072020.026
blastoderm segmentationGO:000735020.025
regulation of anatomical structure sizeGO:00900661010.025
cell morphogenesisGO:00009022960.025
cellular macromolecule catabolic processGO:00442653800.025
regulation of gtp catabolic processGO:00331241800.025
regulation of anatomical structure morphogenesisGO:00226032860.025
sulfur compound metabolic processGO:00067901010.025
cellular chemical homeostasisGO:00550821800.025
cell adhesionGO:00071553250.024
negative regulation of catalytic activityGO:00430863350.024
ubiquitin dependent protein catabolic processGO:00065112060.024
response to biotic stimulusGO:00096072760.024
modification dependent macromolecule catabolic processGO:00436322120.024
cellular amine metabolic processGO:0044106410.024
neuron differentiationGO:00301821380.024
proteasomal protein catabolic processGO:00104981760.024
endocytosisGO:00068971590.024
Mouse
developmental process involved in reproductionGO:0003006660.024
intrinsic apoptotic signaling pathwayGO:00971931270.024
biological adhesionGO:00226103310.023
negative regulation of programmed cell deathGO:00430693210.023
positive regulation of nucleotide catabolic processGO:00308131850.023
regulation of rab protein signal transductionGO:0032483390.023
small molecule biosynthetic processGO:00442831570.023
glycoprotein metabolic processGO:00091001100.023
oocyte differentiationGO:000999420.022
vasodilationGO:004231140.022
neurogenesisGO:00220081690.022
regulation of rab gtpase activityGO:0032313390.022
negative regulation of cellular component organizationGO:00511292350.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
regulation of nucleoside metabolic processGO:00091182090.022
positive regulation of intracellular protein transportGO:0090316760.022
ventricular cardiac muscle cell action potentialGO:0086005150.022
nucleoside monophosphate catabolic processGO:00091251590.022
associative learningGO:000830610.022
lysosomal transportGO:0007041330.021
regulation of mapk cascadeGO:00434082620.021
positive regulation of hydrolase activityGO:00513453310.021
negative regulation of phosphate metabolic processGO:00459362670.021
positive regulation of cellular component movementGO:00512721810.021
segmentationGO:003528240.021
regulation of nucleotide metabolic processGO:00061402690.020
vacuolar transportGO:0007034340.020
mitochondrion organizationGO:00070051560.020
hindbrain developmentGO:003090230.020
regulation of cell divisionGO:00513021160.020
cellular response to hormone stimulusGO:00328701250.020
purine nucleoside monophosphate catabolic processGO:00091281580.019
cellular response to oxygen containing compoundGO:19017012760.019
multi organism reproductive processGO:0044703540.019
cellular modified amino acid metabolic processGO:0006575640.019
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.019
taxisGO:00423301570.019
protein maturationGO:00516042330.019
generation of neuronsGO:00486991520.019
spermatogenesisGO:0007283220.019
purine containing compound biosynthetic processGO:0072522880.018
positive regulation of cellular amine metabolic processGO:003324070.018
cell projection assemblyGO:00300311260.018
positive regulation of cell cycleGO:00457871400.018
negative regulation of protein phosphorylationGO:00019331400.018
multicellular organismal reproductive processGO:0048609400.018
single organism carbohydrate metabolic processGO:00447231930.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.018
embryo developmentGO:00097901230.017
regulation of locomotionGO:00400123290.017
cellular divalent inorganic cation homeostasisGO:00725031280.017
lipid biosynthetic processGO:00086101770.017
rho protein signal transductionGO:0007266260.017
regulation of protein secretionGO:0050708860.017
renal system processGO:0003014250.017
embryonic epithelial tube formationGO:000183840.017
response to radiationGO:00093141510.017
positive regulation of axon extensionGO:004577340.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
immune effector processGO:00022521590.016
adult locomotory behaviorGO:000834410.016
organic hydroxy compound biosynthetic processGO:1901617710.016
leukocyte migrationGO:00509001070.016
response to endoplasmic reticulum stressGO:0034976490.016
positive regulation of cell migrationGO:00303351720.016
regulation of vesicle mediated transportGO:00606271300.016
anterior posterior axis specification embryoGO:000859520.016
regulation of leukocyte migrationGO:0002685630.016
cell part morphogenesisGO:00329901370.016
retrograde transport endosome to golgiGO:0042147450.015
defense response to other organismGO:00985421290.015
organic acid biosynthetic processGO:0016053970.015
cellular response to organonitrogen compoundGO:00714171240.015
tripartite regional subdivisionGO:000735120.015
modification dependent protein catabolic processGO:00199412090.015
positive regulation of organelle organizationGO:00106381950.015
ameboidal type cell migrationGO:00016671350.015
cell fate commitment involved in pattern specificationGO:006058110.015
response to cytokineGO:00340972320.015
response to drugGO:0042493810.015
engulfment of apoptotic cellGO:004365220.015
negative regulation of developmental processGO:00510932470.015
cellular amide metabolic processGO:0043603690.015
protein polyubiquitinationGO:00002091100.015
negative regulation of apoptotic processGO:00430663160.015
cell projection morphogenesisGO:00488581290.015
nucleoside phosphate biosynthetic processGO:19012931090.014
negative regulation of nucleotide biosynthetic processGO:0030809110.014
nucleus localizationGO:005164710.014
anion transmembrane transportGO:0098656760.014
Human Rat
transepithelial chloride transportGO:003032130.014
regulation of cell growthGO:00015581350.014
cell morphogenesis involved in differentiationGO:00009041440.014
carboxylic acid transportGO:0046942630.014
axon cargo transportGO:000808820.014
steroid biosynthetic processGO:0006694460.014
morphogenesis of embryonic epitheliumGO:001633140.014
microtubule based movementGO:0007018320.014
regulation of wnt signaling pathwayGO:00301111230.014
regulation of kinase activityGO:00435493140.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
anterior posterior axis specificationGO:000994820.014
oxidation reduction processGO:00551143960.014
regulation of endocytosisGO:0030100720.014
microtubule cytoskeleton organizationGO:00002261760.014
negative regulation of cell differentiationGO:00455961710.014
wnt signaling pathwayGO:00160551560.014
negative regulation of transportGO:00510511760.013
neuron developmentGO:00486661130.013
negative regulation of multicellular organismal processGO:00512413170.013
microvillus organizationGO:003252820.013
defense response to bacteriumGO:0042742630.013
regulation of cellular phGO:0030641170.013
male gamete generationGO:0048232220.013
regulation of cell migrationGO:00303342890.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
receptor metabolic processGO:0043112810.013
cell projection organizationGO:00300302520.013
neurological system processGO:00508771630.013
intracellular mrna localizationGO:000829810.013
protein catabolic processGO:00301633250.013
sterol transportGO:0015918390.013
cell growthGO:00160491600.012
meiosis iGO:000712740.012
circulatory system developmentGO:00723592620.012
response to peptide hormoneGO:0043434610.012
translationGO:00064121320.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
macromolecule glycosylationGO:0043413630.012
multicellular organism reproductionGO:0032504420.012
glycoprotein biosynthetic processGO:0009101910.012
golgi vesicle fusion to target membraneGO:004821020.012
regulation of nucleotide catabolic processGO:00308112050.012
regulation of cellular response to stressGO:00801352440.012
cellular metal ion homeostasisGO:00068751460.012
negative regulation of nucleotide metabolic processGO:0045980290.012
regulation of multi organism processGO:00439001570.012
leukocyte chemotaxisGO:0030595760.012
regulation of ras protein signal transductionGO:00465781550.012
negative regulation of intracellular signal transductionGO:19025321830.012
regulation of secretionGO:00510461940.012
posttranscriptional regulation of gene expressionGO:00106082130.012
sexual reproductionGO:0019953370.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
blood vessel developmentGO:00015681720.012
regulation of cytoplasmic transportGO:19036491490.012
regulation of phGO:0006885200.011
single organism cell adhesionGO:00986021790.011
reproductionGO:0000003630.011
lens development in camera type eyeGO:000208820.011
brain morphogenesisGO:004885410.011
limbic system developmentGO:002176130.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
sodium ion homeostasisGO:0055078140.011
steroid metabolic processGO:0008202940.011
carboxylic acid catabolic processGO:0046395710.011
cell divisionGO:00513011680.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
chemotaxisGO:00069351570.011
regulation of cell morphogenesisGO:00226041530.011
gamete generationGO:0007276250.011
establishment of protein localization to organelleGO:00725941720.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
canonical wnt signaling pathwayGO:00600701160.011
microtubule based transportGO:0010970210.011
cholesterol metabolic processGO:0008203280.011
actin cytoskeleton organizationGO:00300362070.011
copii vesicle coatingGO:004820820.011
negative regulation of hydrolase activityGO:00513461820.011
transmission of nerve impulseGO:0019226110.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
organ formationGO:004864530.011
photoreceptor cell differentiationGO:004653020.011
nuclear migrationGO:000709710.011
positive regulation of cellular component biogenesisGO:00440891580.010
golgi organizationGO:0007030380.010
regulation of erk1 and erk2 cascadeGO:0070372990.010
lipid transportGO:0006869900.010
positive regulation of locomotionGO:00400171860.010
regulation of cell cycle processGO:00105642660.010
regulation of blood vessel sizeGO:0050880180.010
establishment or maintenance of apical basal cell polarityGO:003508820.010
regulation of peptidase activityGO:00525471800.010
epithelium developmentGO:00604292270.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.010
mapk cascadeGO:00001652880.010
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.010
carbohydrate metabolic processGO:00059752070.010
positive regulation of ion transportGO:0043270870.010
positive regulation of intracellular transportGO:00323881040.010
phospholipase c activating dopamine receptor signaling pathwayGO:006015820.010
cellular macromolecular complex assemblyGO:00346223240.010

CLCN3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
respiratory system diseaseDOID:1579140.600
lower respiratory tract diseaseDOID:0050161130.600
musculoskeletal system diseaseDOID:172230.034
Human
brain diseaseDOID:936730.028
central nervous system diseaseDOID:3311860.028
epilepsy syndromeDOID:1826410.028
variable age at onset electroclinical syndromeDOID:005070680.028
nervous system diseaseDOID:8634310.028
electroclinical syndromeDOID:0050701320.028
progressive myoclonus epilepsyDOID:89180.028
immune system diseaseDOID:29141550.024
cancerDOID:1621670.021
disease of cellular proliferationDOID:145661740.021
hematopoietic system diseaseDOID:741000.017
disease of metabolismDOID:00146672950.012
Human
neurodegenerative diseaseDOID:12891020.011