Homo sapiens

59 known processes

GLS

glutaminase

(Aliases: GLS1,AAD20,KIAA0838,DKFZp686O15119,FLJ10358)

GLS biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organophosphate catabolic processGO:00464344300.170
regulation of cellular amine metabolic processGO:0033238110.151
nucleoside catabolic processGO:00091644080.144
cellular ketone metabolic processGO:0042180800.134
membrane organizationGO:00610242920.130
cellular amine metabolic processGO:0044106410.099
cellular amino acid metabolic processGO:00065201160.099
transmembrane transportGO:00550853990.096
gtp catabolic processGO:00061842370.093
regulation of cellular ketone metabolic processGO:0010565500.093
single organism membrane organizationGO:00448022680.088
nucleoside triphosphate catabolic processGO:00091433940.087
purine ribonucleoside triphosphate metabolic processGO:00092054110.086
purine nucleoside triphosphate catabolic processGO:00091463920.085
regulation of cell differentiationGO:00455953930.084
ribonucleoside catabolic processGO:00424544060.084
purine nucleotide catabolic processGO:00061954050.084
ion transmembrane transportGO:00342203380.083
purine ribonucleotide catabolic processGO:00091544040.083
nervous system developmentGO:00073992930.079
ribonucleoside triphosphate metabolic processGO:00091994120.079
small gtpase mediated signal transductionGO:0007264780.078
purine nucleoside catabolic processGO:00061523980.078
purine ribonucleoside catabolic processGO:00461303980.077
cellular lipid metabolic processGO:00442553030.075
regulation of cellular amino acid metabolic processGO:000652160.075
guanosine containing compound catabolic processGO:19010692390.075
nucleoside triphosphate metabolic processGO:00091414220.074
post embryonic developmentGO:000979120.073
ras protein signal transductionGO:0007265730.072
amine metabolic processGO:0009308440.072
ribonucleoside triphosphate catabolic processGO:00092033910.070
nucleotide catabolic processGO:00091664080.070
purine ribonucleoside metabolic processGO:00461284370.070
nucleoside phosphate catabolic processGO:19012924120.069
purine containing compound catabolic processGO:00725234110.068
purine nucleoside triphosphate metabolic processGO:00091444120.068
regulation of cellular component biogenesisGO:00440872810.068
single organism cellular localizationGO:19025803320.067
response to oxygen containing compoundGO:19017003690.067
positive regulation of cellular amino acid metabolic processGO:004576430.066
positive regulation of cellular amine metabolic processGO:003324070.065
neuromuscular junction developmentGO:000752830.064
cell developmentGO:00484683280.063
cation transportGO:00068123310.062
cytoplasmic transportGO:00164823790.061
gtp metabolic processGO:00460392390.061
glycosyl compound catabolic processGO:19016584130.061
chemical homeostasisGO:00488783060.060
regulation of cell cycleGO:00517263930.060
lipid metabolic processGO:00066293810.060
positive regulation of protein phosphorylationGO:00019343130.060
metal ion transportGO:00300012720.060
actin filament based processGO:00300292240.059
ribonucleotide catabolic processGO:00092614050.059
oxidation reduction processGO:00551143960.059
purine ribonucleoside triphosphate catabolic processGO:00092073910.058
positive regulation of catabolic processGO:00098963100.058
anatomical structure formation involved in morphogenesisGO:00486462840.058
cell projection organizationGO:00300302520.057
positive regulation of nucleotide metabolic processGO:00459812300.056
oogenesisGO:004847720.054
inorganic ion transmembrane transportGO:00986602310.054
system processGO:00030083490.054
Mouse
positive regulation of transportGO:00510503360.053
ion homeostasisGO:00508012300.051
guanosine containing compound metabolic processGO:19010682440.051
monocarboxylic acid metabolic processGO:00327871850.051
determination of adult lifespanGO:000834020.050
positive regulation of hydrolase activityGO:00513453310.050
positive regulation of cellular catabolic processGO:00313312840.049
regulation of locomotionGO:00400123290.049
cytokine productionGO:00018162470.049
cellular response to endogenous stimulusGO:00714953360.049
positive regulation of phosphorylationGO:00423273940.048
response to abiotic stimulusGO:00096283360.048
regulation of cellular component movementGO:00512703340.048
cation homeostasisGO:00550801890.045
anion transportGO:00068201610.045
protein catabolic processGO:00301633250.045
positive regulation of cell differentiationGO:00455972110.044
cation transmembrane transportGO:00986552380.044
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.043
positive regulation of cellular component organizationGO:00511303760.043
regulation of gtp catabolic processGO:00331241800.043
vesicle mediated transportGO:00161923710.043
cell morphogenesisGO:00009022960.042
intracellular protein transportGO:00068862700.042
regenerationGO:003109940.042
negative regulation of cell deathGO:00605483450.041
reactive oxygen species biosynthetic processGO:190340940.041
multicellular organismal agingGO:001025930.041
regulation of nucleotide metabolic processGO:00061402690.041
rho protein signal transductionGO:0007266260.041
mitochondrion organizationGO:00070051560.041
positive regulation of purine nucleotide metabolic processGO:19005442270.041
positive regulation of nucleoside metabolic processGO:00459791860.040
organonitrogen compound biosynthetic processGO:19015662000.040
regulation of cell motilityGO:20001452990.040
locomotory behaviorGO:000762610.040
negative regulation of catalytic activityGO:00430863350.039
enzyme linked receptor protein signaling pathwayGO:00071673030.039
regulation of cell migrationGO:00303342890.039
inorganic cation transmembrane transportGO:00986621940.039
regulation of nucleotide catabolic processGO:00308112050.039
positive regulation of gtpase activityGO:00435471660.038
biological adhesionGO:00226103310.038
positive regulation of purine nucleotide catabolic processGO:00331231850.038
cellular chemical homeostasisGO:00550821800.038
protein localization to organelleGO:00333652800.038
female gamete generationGO:000729220.037
positive regulation of nucleotide catabolic processGO:00308131850.037
organic anion transportGO:00157111030.037
axon regenerationGO:003110310.037
regulation of nucleoside metabolic processGO:00091182090.036
defense responseGO:00069523150.036
regulation of reactive oxygen species metabolic processGO:2000377410.036
regulation of protein localizationGO:00328802960.036
negative regulation of phosphate metabolic processGO:00459362670.036
mitotic cell cycleGO:00002783260.035
regulation of purine nucleotide metabolic processGO:19005422640.035
negative regulation of protein metabolic processGO:00512483910.035
cellular cation homeostasisGO:00300031630.035
peptidyl serine phosphorylationGO:00181051010.035
regulation of anatomical structure morphogenesisGO:00226032860.035
regulation of ras protein signal transductionGO:00465781550.034
reactive nitrogen species metabolic processGO:200105730.034
cellular response to oxygen containing compoundGO:19017012760.034
negative regulation of phosphorus metabolic processGO:00105632670.034
organ morphogenesisGO:00098871470.033
regulation of purine nucleotide catabolic processGO:00331212050.033
actin cytoskeleton organizationGO:00300362070.033
secretionGO:00469032540.033
protein localization to membraneGO:00726571600.033
positive regulation of developmental processGO:00510943140.033
positive regulation of reactive oxygen species metabolic processGO:2000379240.033
regulation of proteolysisGO:00301622930.032
response to growth factorGO:00708482050.032
regulation of transferase activityGO:00513383550.032
endomembrane system organizationGO:00102561960.032
response to axon injuryGO:004867810.032
establishment of protein localization to membraneGO:00901501210.032
microtubule cytoskeleton organizationGO:00002261760.032
lipid biosynthetic processGO:00086101770.032
cellular homeostasisGO:00197251960.031
regulation of cell developmentGO:00602841610.031
regulation of mapk cascadeGO:00434082620.031
positive regulation of gtp catabolic processGO:00331261660.031
regulation of small gtpase mediated signal transductionGO:00510561560.031
dephosphorylationGO:00163112090.031
oocyte differentiationGO:000999420.030
mapk cascadeGO:00001652880.030
negative regulation of cellular component organizationGO:00511292350.030
reactive oxygen species metabolic processGO:0072593750.030
Human
regulation of cell cycle processGO:00105642660.030
positive regulation of immune system processGO:00026842830.030
cellular protein complex assemblyGO:00436231880.030
calcium ion transportGO:00068161470.030
rhythmic behaviorGO:000762220.029
response to nitrogen compoundGO:19016981840.029
positive regulation of cytokine productionGO:00018191670.029
circulatory system developmentGO:00723592620.029
regulation of protein serine threonine kinase activityGO:00719001790.029
cellular macromolecule catabolic processGO:00442653800.029
divalent inorganic cation transportGO:00725111580.028
negative regulation of cellular amine metabolic processGO:003323930.028
ribonucleoside monophosphate metabolic processGO:00091611870.028
protein processingGO:00164852260.028
positive regulation of ras gtpase activityGO:00323201170.028
regulation of protein kinase activityGO:00458592890.028
mitotic cell cycle processGO:19030472860.028
neuron projection regenerationGO:003110210.028
regulation of reactive oxygen species biosynthetic processGO:190342630.028
positive regulation of reactive oxygen species biosynthetic processGO:190342820.027
response to external biotic stimulusGO:00432072610.027
organic hydroxy compound metabolic processGO:19016151470.027
regulation of vesicle mediated transportGO:00606271300.027
signal transduction by phosphorylationGO:00230142970.027
protein modification by small protein conjugationGO:00324463420.027
response to organonitrogen compoundGO:00102431560.026
single organism carbohydrate metabolic processGO:00447231930.026
regulation of cell projection organizationGO:00313441070.026
negative regulation of apoptotic processGO:00430663160.026
cellular component morphogenesisGO:00329893140.026
cellular response to growth factor stimulusGO:00713631970.026
cellular macromolecular complex assemblyGO:00346223240.026
negative regulation of developmental processGO:00510932470.026
cellular response to dna damage stimulusGO:00069743790.026
protein targetingGO:00066051870.026
peptidyl serine modificationGO:00182091060.026
cell growthGO:00160491600.026
regulation of cytokine productionGO:00018172320.026
regulation of kinase activityGO:00435493140.025
adult locomotory behaviorGO:000834410.025
regulation of gtpase activityGO:00430871800.025
cellular ion homeostasisGO:00068731680.025
cell activationGO:00017752130.025
memoryGO:000761330.025
wnt signaling pathwayGO:00160551560.024
regulation of establishment of protein localizationGO:00702012420.024
carbohydrate derivative biosynthetic processGO:19011372070.024
regulation of synaptic plasticityGO:004816730.024
response to biotic stimulusGO:00096072760.024
actin filament based movementGO:0030048170.024
regulation of ion transportGO:00432691890.024
microtubule based processGO:00070172100.024
oocyte developmentGO:004859910.024
actin filament organizationGO:00070151280.023
segmentationGO:003528240.023
generation of neuronsGO:00486991520.023
negative regulation of hydrolase activityGO:00513461820.023
metal ion homeostasisGO:00550651690.023
divalent metal ion transportGO:00708381520.023
negative regulation of cellular protein metabolic processGO:00322693530.023
regulation of protein transportGO:00512232130.023
fatty acid metabolic processGO:00066311150.023
negative regulation of intracellular signal transductionGO:19025321830.023
covalent chromatin modificationGO:00165692540.023
cell cycle phase transitionGO:00447701730.023
protein acylationGO:00435431380.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
negative regulation of multi organism processGO:0043901920.022
protein maturationGO:00516042330.022
regulation of cytoskeleton organizationGO:00514931770.022
neurogenesisGO:00220081690.022
neurological system processGO:00508771630.022
Mouse
carbohydrate metabolic processGO:00059752070.022
response to other organismGO:00517072610.022
mitotic cell cycle phase transitionGO:00447721620.022
protein oligomerizationGO:00512591730.022
positive regulation of transferase activityGO:00513472270.022
negative regulation of multicellular organismal processGO:00512413170.022
cardiovascular system developmentGO:00723582620.022
negative regulation of programmed cell deathGO:00430693210.022
chromatin modificationGO:00165682980.022
spermatid developmentGO:000728640.022
establishment of protein localization to organelleGO:00725941720.022
negative regulation of transportGO:00510511760.021
alcohol metabolic processGO:00060661140.021
cellular metal ion homeostasisGO:00068751460.021
response to inorganic substanceGO:00100351270.021
regulation of cellular response to stressGO:00801352440.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
phospholipid metabolic processGO:0006644990.021
regulation of immune responseGO:00507762010.021
histone modificationGO:00165702510.021
small molecule biosynthetic processGO:00442831570.021
morphogenesis of embryonic epitheliumGO:001633140.021
calcium ion transmembrane transportGO:0070588760.021
immune system developmentGO:00025201950.021
cardiac muscle cell contractionGO:008600340.021
positive regulation of ion transportGO:0043270870.021
regulation of secretionGO:00510461940.021
nucleoside monophosphate metabolic processGO:00091231910.020
epithelium developmentGO:00604292270.020
cellular response to nitrogen compoundGO:19016991440.020
regulation of growthGO:00400081650.020
small molecule catabolic processGO:0044282920.020
motor neuron axon guidanceGO:000804520.020
sequestering of calcium ionGO:0051208170.020
muscle contractionGO:0006936730.020
negative regulation of transferase activityGO:00513481240.020
chromatin organizationGO:00063253510.020
plasma membrane organizationGO:00070091150.020
hemopoiesisGO:00300971800.020
secretion by cellGO:00329402260.020
regulation of cell morphogenesisGO:00226041530.020
cellular protein catabolic processGO:00442572610.020
regulation of cell growthGO:00015581350.020
purine ribonucleoside monophosphate metabolic processGO:00091671860.020
anion transmembrane transportGO:0098656760.020
regulation of secretion by cellGO:19035301770.019
positive regulation of cell proliferationGO:00082843010.019
blood vessel morphogenesisGO:00485141620.019
response to oxidative stressGO:00069791210.019
positive regulation of programmed cell deathGO:00430682490.019
cell projection morphogenesisGO:00488581290.019
negative regulation of protein maturationGO:19033181420.019
positive regulation of apoptotic processGO:00430652460.019
endosomal transportGO:00161971290.019
regulation of ion transmembrane transportGO:00347651320.019
regulation of intracellular transportGO:00323861950.019
neuron projection developmentGO:00311751060.019
engulfment of apoptotic cellGO:004365220.019
chemotaxisGO:00069351570.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
growthGO:00400072020.019
atp metabolic processGO:00460341760.019
spermatid differentiationGO:004851540.019
syncytium formation by plasma membrane fusionGO:000076820.019
sequestering of metal ionGO:0051238240.019
peptidyl tyrosine phosphorylationGO:00181081700.019
positive regulation of kinase activityGO:00336742040.018
leukocyte activationGO:00453211640.018
response to organic cyclic compoundGO:00140702040.018
matingGO:000761810.018
nerve developmentGO:002167540.018
response to radiationGO:00093141510.018
peripheral nervous system developmentGO:000742220.018
calcium ion homeostasisGO:00550741220.018
associative learningGO:000830610.018
positive regulation of locomotionGO:00400171860.018
cell adhesionGO:00071553250.018
response to woundingGO:00096111680.018
organic acid transportGO:0015849650.018
regulation of peptidase activityGO:00525471800.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
organelle assemblyGO:00709251760.018
negative regulation of cell cycleGO:00457861930.018
hindbrain developmentGO:003090230.017
cellular calcium ion homeostasisGO:00068741170.017
lipid transportGO:0006869900.017
positive regulation of cell motilityGO:20001471770.017
taxisGO:00423301570.017
regulation of neuron projection developmentGO:0010975570.017
carboxylic acid transportGO:0046942630.017
regulation of actin filament based processGO:00329701410.017
regulation of ras gtpase activityGO:00323181280.017
regulation of cell cycle phase transitionGO:19019871260.017
regulation of protein processingGO:00706131500.017
symbiosis encompassing mutualism through parasitismGO:00444031560.017
sulfur compound metabolic processGO:00067901010.017
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.017
cardiac muscle contractionGO:0060048340.017
cell projection assemblyGO:00300311260.017
neuron differentiationGO:00301821380.017
regulation of protein complex assemblyGO:00432541470.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
negative regulation of phosphorylationGO:00423261740.017
glycoprotein metabolic processGO:00091001100.017
nucleocytoplasmic transportGO:00069131760.017
negative regulation of cell proliferationGO:00082852280.017
organic acid biosynthetic processGO:0016053970.017
response to lipidGO:00339932060.017
organ formationGO:004864530.017
regulation of homeostatic processGO:00328441210.016
regulation of response to external stimulusGO:00321012220.016
cellular response to cytokine stimulusGO:00713451810.016
limbic system developmentGO:002176130.016
peptidyl threonine modificationGO:0018210450.016
protein localization to nucleusGO:00345041360.016
positive regulation of immune responseGO:00507781590.016
golgi vesicle transportGO:0048193800.016
regulation of endopeptidase activityGO:00525481700.016
monovalent inorganic cation transportGO:00156721280.016
protein targeting to nucleusGO:00447441040.016
lipid localizationGO:00108761060.016
immune responseGO:00069553070.016
epithelium migrationGO:00901321190.016
actin mediated cell contractionGO:0070252120.016
defense response to other organismGO:00985421290.016
regulation of transmembrane transportGO:00347621390.016
epithelial cell migrationGO:00106311190.016
blastoderm segmentationGO:000735020.016
circadian behaviorGO:004851220.016
cellular divalent inorganic cation homeostasisGO:00725031280.016
positive regulation of cell developmentGO:0010720920.016
negative regulation of protein modification processGO:00314002000.016
regulation of bindingGO:00510981110.016
muscle system processGO:0003012810.016
negative regulation of cell differentiationGO:00455961710.016
negative regulation of cell cycle processGO:00109481210.016
single organism reproductive processGO:0044702980.016
regulation of dephosphorylationGO:0035303960.016
positive regulation of cell cycleGO:00457871400.015
positive regulation of protein serine threonine kinase activityGO:00719021190.015
organelle localizationGO:0051640840.015
intra s dna damage checkpointGO:003157340.015
regulation of membrane potentialGO:0042391950.015
positive regulation of cellular component biogenesisGO:00440891580.015
organophosphate biosynthetic processGO:00904071630.015
peptidyl tyrosine modificationGO:00182121700.015
protein ubiquitinationGO:00165673140.015
positive regulation of cell migrationGO:00303351720.015
positive regulation of protein kinase activityGO:00458601900.015
brain developmentGO:0007420970.015
regulation of rho protein signal transductionGO:0035023790.015
cellular response to organonitrogen compoundGO:00714171240.015
regulation of transporter activityGO:0032409820.015
positive regulation of gliogenesisGO:001401540.015
myoblast fusionGO:000752010.015
endothelial cell migrationGO:0043542860.015
cerebral cortex cell migrationGO:002179530.015
positive regulation of cellular component movementGO:00512721810.015
protein acetylationGO:00064731160.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
neuron developmentGO:00486661130.015
carboxylic acid catabolic processGO:0046395710.015
interspecies interaction between organismsGO:00444191560.014
cellular response to oxidative stressGO:0034599850.014
inner ear morphogenesisGO:004247240.014
nitrogen compound transportGO:00717051910.014
modification dependent macromolecule catabolic processGO:00436322120.014
anterior posterior axis specification embryoGO:000859520.014
regulation of cell adhesionGO:00301551660.014
behaviorGO:00076101120.014
Mouse
regulation of cell activationGO:00508651250.014
regulation of cytoplasmic transportGO:19036491490.014
maintenance of locationGO:00512351120.014
carboxylic acid biosynthetic processGO:0046394970.014
negative regulation of synaptic transmissionGO:005080520.014
negative regulation of cell migrationGO:00303361020.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
regulation of mitotic cell cycleGO:00073461890.014
endocytosisGO:00068971590.014
lipid modificationGO:0030258840.014
compound eye developmentGO:004874910.014
long term memoryGO:000761620.014
regulation of cellular component sizeGO:0032535820.014
wound healingGO:00420601150.014
cell part morphogenesisGO:00329901370.014
neurotransmitter secretionGO:000726940.014
multi organism cellular processGO:00447641560.014
proteasomal protein catabolic processGO:00104981760.014
positive regulation of secretionGO:00510471160.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
negative regulation of protein phosphorylationGO:00019331400.014
atp catabolic processGO:00062001570.014
lymphocyte homeostasisGO:000226040.014
blood vessel developmentGO:00015681720.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
glycerolipid metabolic processGO:00464861070.014
positive regulation of organelle organizationGO:00106381950.014
response to cytokineGO:00340972320.014
cell junction organizationGO:0034330790.014
positive regulation of cell deathGO:00109422630.014
organic acid catabolic processGO:0016054710.014
anterior posterior axis specificationGO:000994820.014
regulation of protein catabolic processGO:00421761550.013
monovalent inorganic cation homeostasisGO:0055067370.013
regulation of protein modification by small protein conjugation or removalGO:19033201070.013
apoptotic signaling pathwayGO:00971902680.013
negative regulation of growthGO:0045926970.013
negative regulation of protein processingGO:00109551420.013
regulation of protein maturationGO:19033171500.013
ameboidal type cell migrationGO:00016671350.013
sensory perception of smellGO:000760820.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
cartilage condensationGO:000150210.013
nuclear transportGO:00511691790.013
regulation of wnt signaling pathwayGO:00301111230.013
negative regulation of proteolysisGO:00458611320.013
innate immune responseGO:00450871780.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
cellular response to abiotic stimulusGO:00712141170.013
epithelial cell proliferationGO:00506731280.013
i kappab kinase nf kappab signalingGO:00072491660.013
positive regulation of secretion by cellGO:19035321080.013
negative regulation of cell cycle phase transitionGO:1901988890.013
sodium ion transportGO:0006814610.013
protein importGO:00170381300.013
single organism nuclear importGO:19025931040.013
divalent inorganic cation homeostasisGO:00725071360.013
negative regulation of organelle organizationGO:00106391260.013
angiogenesisGO:00015251470.013
regulation of mitotic cell cycle phase transitionGO:19019901180.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
single organismal cell cell adhesionGO:00163371480.013
tripartite regional subdivisionGO:000735120.013
metencephalon developmentGO:002203720.013
positive regulation of protein transportGO:00512221350.013
cell substrate adhesionGO:00315891320.013
cell divisionGO:00513011680.013
central nervous system developmentGO:00074171230.013
reproductive processGO:00224141060.013
regulation of apoptotic signaling pathwayGO:20012331750.013
protein localization to plasma membraneGO:0072659930.013
tissue regenerationGO:004224630.013
regulation of meiotic cell cycleGO:005144540.013
endothelial cell proliferationGO:0001935650.013
regulation of neurotransmitter secretionGO:004692830.013
collateral sproutingGO:004866820.012
organophosphate ester transportGO:0015748320.012
negative regulation of immune system processGO:00026831360.012
regulation of nervous system developmentGO:0051960880.012
primary neural tube formationGO:001402030.012
cellular carbohydrate metabolic processGO:0044262840.012
establishment of protein localization to plasma membraneGO:0090002680.012
sensory perceptionGO:00076001030.012
regulation of anatomical structure sizeGO:00900661010.012

GLS disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.026
inherited metabolic disorderDOID:6552420.024
nervous system diseaseDOID:8634310.021
sensory system diseaseDOID:00501552030.021
musculoskeletal system diseaseDOID:172230.020
central nervous system diseaseDOID:3311860.019
organ system cancerDOID:00506861640.017
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
eye diseaseDOID:56141490.015
eye and adnexa diseaseDOID:14921500.015
connective tissue diseaseDOID:651090.013
neurodegenerative diseaseDOID:12891020.012