Homo sapiens

107 known processes

PRAME

preferentially expressed antigen in melanoma

(Aliases: OIP4,CT130,MAPE)

PRAME biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.159
cellular macromolecule catabolic processGO:00442653800.079
segmentationGO:003528240.076
anterior posterior axis specificationGO:000994820.076
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.069
cell developmentGO:00484683280.066
negative regulation of protein metabolic processGO:00512483910.065
anterior posterior axis specification embryoGO:000859520.063
cellular amine metabolic processGO:0044106410.062
blastoderm segmentationGO:000735020.060
cellular component morphogenesisGO:00329893140.058
determination of adult lifespanGO:000834020.058
negative regulation of cellular protein metabolic processGO:00322693530.056
regulation of cell differentiationGO:00455953930.053
protein ubiquitinationGO:00165673140.050
regulation of cellular ketone metabolic processGO:0010565500.049
positive regulation of cellular amino acid metabolic processGO:004576430.049
cellular amino acid metabolic processGO:00065201160.049
negative regulation of catalytic activityGO:00430863350.046
regulation of cellular amino acid metabolic processGO:000652160.046
negative regulation of developmental processGO:00510932470.045
regulation of cell cycleGO:00517263930.044
multicellular organismal agingGO:001025930.043
cellular ketone metabolic processGO:0042180800.043
tripartite regional subdivisionGO:000735120.041
amine metabolic processGO:0009308440.040
regulation of cellular amine metabolic processGO:0033238110.040
circulatory system developmentGO:00723592620.040
neuron fate commitmentGO:004866320.040
cell projection organizationGO:00300302520.039
female gamete generationGO:000729220.038
morphogenesis of embryonic epitheliumGO:001633140.037
protein modification by small protein conjugationGO:00324463420.036
neuromuscular junction developmentGO:000752830.036
regulation of proteolysisGO:00301622930.036
regulation of transferase activityGO:00513383550.035
cell morphogenesis involved in differentiationGO:00009041440.034
tissue migrationGO:00901301190.034
cellular response to endogenous stimulusGO:00714953360.033
positive regulation of meiotic cell cycleGO:005144620.033
regulation of meiotic cell cycleGO:005144540.032
cell morphogenesisGO:00009022960.032
neurogenesisGO:00220081690.032
mitotic cell cycle processGO:19030472860.032
negative regulation of phosphorus metabolic processGO:00105632670.032
oogenesisGO:004847720.031
regulation of ligase activityGO:0051340290.031
cytoplasmic transportGO:00164823790.031
negative regulation of protein modification processGO:00314002000.031
regulation of kinase activityGO:00435493140.030
enzyme linked receptor protein signaling pathwayGO:00071673030.030
response to lipidGO:00339932060.030
mitotic sister chromatid segregationGO:0000070530.030
negative regulation of cellular amine metabolic processGO:003323930.030
stem cell divisionGO:001714520.029
cell adhesionGO:00071553250.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
regulation of anatomical structure morphogenesisGO:00226032860.029
proteolysis involved in cellular protein catabolic processGO:00516032440.029
forelimb morphogenesisGO:003513640.028
embryonic epithelial tube formationGO:000183840.028
positive regulation of cell differentiationGO:00455972110.028
negative regulation of multicellular organismal processGO:00512413170.028
positive regulation of cellular amine metabolic processGO:003324070.028
negative regulation of cellular amino acid metabolic processGO:004576320.028
ameboidal type cell migrationGO:00016671350.028
detection of chemical stimulus involved in sensory perception of smellGO:005091120.027
vasculature developmentGO:00019441810.027
positive regulation of cellular component organizationGO:00511303760.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
taxisGO:00423301570.027
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
positive regulation of transferase activityGO:00513472270.027
modification dependent protein catabolic processGO:00199412090.026
cellular protein catabolic processGO:00442572610.026
secretionGO:00469032540.026
cell part morphogenesisGO:00329901370.026
chemotaxisGO:00069351570.026
regulation of cell migrationGO:00303342890.025
epithelium developmentGO:00604292270.025
memoryGO:000761330.025
regulation of locomotionGO:00400123290.025
positive regulation of cell proliferationGO:00082843010.025
regulation of hormone levelsGO:00108171250.025
glial cell migrationGO:000834740.025
cellular macromolecular complex assemblyGO:00346223240.025
neuron differentiationGO:00301821380.025
regulation of cell cycle processGO:00105642660.024
vesicle mediated transportGO:00161923710.024
regulation of protein kinase activityGO:00458592890.024
regulation of protein ubiquitinationGO:0031396950.024
epithelium migrationGO:00901321190.024
epithelial cell differentiationGO:00308551410.024
positive regulation of transportGO:00510503360.024
positive regulation of proteolysisGO:00458621420.024
cardiovascular system developmentGO:00723582620.024
immune responseGO:00069553070.024
regulation of cellular component movementGO:00512703340.024
chromatin modificationGO:00165682980.024
prostate gland morphogenesisGO:006051210.024
meiotic chromosome segregationGO:004513240.024
regulation of proteasomal protein catabolic processGO:0061136870.023
system processGO:00030083490.023
single organism reproductive processGO:0044702980.023
nervous system developmentGO:00073992930.023
inner ear morphogenesisGO:004247240.023
biological adhesionGO:00226103310.023
locomotory behaviorGO:000762610.022
negative regulation of apoptotic processGO:00430663160.022
negative regulation of phosphate metabolic processGO:00459362670.022
protein acylationGO:00435431380.022
protein acetylationGO:00064731160.022
hindbrain developmentGO:003090230.022
wnt signaling pathwayGO:00160551560.022
protein catabolic processGO:00301633250.022
nucleoside triphosphate metabolic processGO:00091414220.022
intracellular protein transportGO:00068862700.022
mitotic cell cycleGO:00002783260.022
regulation of cellular component biogenesisGO:00440872810.022
regulation of mitotic cell cycleGO:00073461890.022
nitrogen compound transportGO:00717051910.022
response to abiotic stimulusGO:00096283360.022
posttranscriptional regulation of gene expressionGO:00106082130.022
regulation of chromosome organizationGO:00330441030.021
regenerationGO:003109940.021
regulation of ubiquitin protein transferase activityGO:0051438280.021
protein localization to organelleGO:00333652800.021
purine ribonucleoside metabolic processGO:00461284370.021
prostate gland developmentGO:003085030.021
actin filament based processGO:00300292240.021
nerve developmentGO:002167540.021
regulation of protein catabolic processGO:00421761550.021
purine ribonucleotide catabolic processGO:00091544040.021
motor neuron axon guidanceGO:000804520.021
negative regulation of cell cycleGO:00457861930.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
specification of organ identityGO:001009230.021
glycosyl compound catabolic processGO:19016584130.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
nucleoside phosphate catabolic processGO:19012924120.021
generation of neuronsGO:00486991520.021
negative regulation of cell deathGO:00605483450.021
positive regulation of developmental processGO:00510943140.021
blood vessel developmentGO:00015681720.021
organophosphate catabolic processGO:00464344300.021
regulation of apoptotic signaling pathwayGO:20012331750.020
nucleotide catabolic processGO:00091664080.020
epithelial cell migrationGO:00106311190.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.020
embryonic forelimb morphogenesisGO:003511540.020
endothelial cell migrationGO:0043542860.020
organ formationGO:004864530.020
positive regulation of apoptotic processGO:00430652460.020
oocyte developmentGO:004859910.020
protein maturationGO:00516042330.020
cellular response to cytokine stimulusGO:00713451810.020
long term memoryGO:000761620.020
establishment of nucleus localizationGO:004002310.020
cell cycle checkpointGO:00000751170.019
small gtpase mediated signal transductionGO:0007264780.019
microtubule based processGO:00070172100.019
regulation of cytokine productionGO:00018172320.019
response to oxygen containing compoundGO:19017003690.019
neuron developmentGO:00486661130.019
cranial nerve developmentGO:002154540.019
regulation of cell divisionGO:00513021160.019
cell divisionGO:00513011680.019
chromatin organizationGO:00063253510.019
compound eye developmentGO:004874910.019
pattern specification processGO:0007389430.019
reproductive processGO:00224141060.019
growthGO:00400072020.019
mitotic nuclear divisionGO:00070671190.019
negative regulation of hydrolase activityGO:00513461820.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
purine nucleoside catabolic processGO:00061523980.019
negative regulation of programmed cell deathGO:00430693210.019
positive regulation of cellular catabolic processGO:00313312840.019
ribonucleoside catabolic processGO:00424544060.019
thymocyte apoptotic processGO:007024220.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
mitotic sister chromatid separationGO:0051306180.018
regulation of mitosisGO:0007088630.018
negative regulation of cell differentiationGO:00455961710.018
defense responseGO:00069523150.018
adult locomotory behaviorGO:000834410.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
membrane organizationGO:00610242920.018
single organism membrane organizationGO:00448022680.018
regulation of secretion by cellGO:19035301770.018
single organism cellular localizationGO:19025803320.018
primary neural tube formationGO:001402030.018
cell projection morphogenesisGO:00488581290.018
ras protein signal transductionGO:0007265730.018
positive regulation of catabolic processGO:00098963100.018
epidermis morphogenesisGO:004873030.018
regulation of cellular response to stressGO:00801352440.018
negative regulation of protein kinase activityGO:0006469980.018
peptidyl tyrosine modificationGO:00182121700.018
actin cytoskeleton organizationGO:00300362070.018
regulation of cell growthGO:00015581350.018
positive regulation of hydrolase activityGO:00513453310.018
regulation of cytoskeleton organizationGO:00514931770.018
organonitrogen compound biosynthetic processGO:19015662000.018
peripheral nervous system developmentGO:000742220.017
regulation of protein modification by small protein conjugation or removalGO:19033201070.017
organelle fissionGO:00482851490.017
cell cell signalingGO:00072671550.017
negative regulation of cellular component organizationGO:00511292350.017
positive regulation of protein phosphorylationGO:00019343130.017
response to other organismGO:00517072610.017
carbohydrate derivative biosynthetic processGO:19011372070.017
protein localization to membraneGO:00726571600.017
organ morphogenesisGO:00098871470.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.017
nucleoside catabolic processGO:00091644080.017
regulation of cell motilityGO:20001452990.017
positive regulation of cell cycle processGO:00900681060.017
morphogenesis of a polarized epitheliumGO:000173830.017
cellular protein complex assemblyGO:00436231880.017
positive regulation of immune system processGO:00026842830.017
regulation of actin filament based processGO:00329701410.017
positive regulation of cell deathGO:00109422630.017
regulation of cell cycle phase transitionGO:19019871260.017
embryonic camera type eye developmentGO:003107620.017
cardiac muscle cell contractionGO:008600340.017
sister chromatid segregationGO:0000819540.017
negative regulation of cell proliferationGO:00082852280.017
skeletal system developmentGO:0001501790.017
cytokine productionGO:00018162470.017
oocyte differentiationGO:000999420.017
proteasomal protein catabolic processGO:00104981760.017
rho protein signal transductionGO:0007266260.017
ribonucleotide catabolic processGO:00092614050.016
neuron projection developmentGO:00311751060.016
negative regulation of wnt signaling pathwayGO:0030178690.016
positive regulation of secretionGO:00510471160.016
tissue morphogenesisGO:0048729960.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of cell morphogenesisGO:00226041530.016
cellular response to dna damage stimulusGO:00069743790.016
regionalizationGO:0003002290.016
extraocular skeletal muscle developmentGO:000207410.016
chromosome segregationGO:00070591140.016
negative regulation of cell migrationGO:00303361020.016
actin mediated cell contractionGO:0070252120.016
organelle assemblyGO:00709251760.016
cell fate determinationGO:000170930.016
endochondral bone morphogenesisGO:006035030.016
maintenance of locationGO:00512351120.016
establishment of organelle localizationGO:0051656590.016
cell cycle phase transitionGO:00447701730.016
neuron remodelingGO:001632220.016
purine nucleotide catabolic processGO:00061954050.016
epithelial cell proliferationGO:00506731280.016
morphogenesis of an epitheliumGO:0002009600.016
spinal cord developmentGO:002151040.016
forebrain regionalizationGO:002187130.016
regulation of purine nucleotide metabolic processGO:19005422640.016
negative regulation of transferase activityGO:00513481240.016
cellular response to oxygen containing compoundGO:19017012760.016
apoptotic signaling pathwayGO:00971902680.016
nucleus localizationGO:005164710.015
regulation of cell developmentGO:00602841610.015
copulationGO:000762010.015
response to organic cyclic compoundGO:00140702040.015
spermatid differentiationGO:004851540.015
nuclear divisionGO:00002801280.015
photoreceptor cell differentiationGO:004653020.015
protein processingGO:00164852260.015
positive regulation of secretion by cellGO:19035321080.015
regulation of secretionGO:00510461940.015
cell chemotaxisGO:00603261120.015
positive regulation of phosphorylationGO:00423273940.015
regulation of protein localizationGO:00328802960.015
positive regulation of cellular component biogenesisGO:00440891580.015
hormone transportGO:0009914680.015
secretion by cellGO:00329402260.015
multi organism cellular processGO:00447641560.015
syncytium formation by plasma membrane fusionGO:000076820.015
forebrain generation of neuronsGO:002187230.015
peptidyl tyrosine phosphorylationGO:00181081700.015
covalent chromatin modificationGO:00165692540.015
single organism carbohydrate metabolic processGO:00447231930.015
protein targetingGO:00066051870.015
regulation of cell adhesionGO:00301551660.015
nuclear transportGO:00511691790.014
cellular response to lipidGO:00713961270.014
purine containing compound catabolic processGO:00725234110.014
pituitary gland developmentGO:002198320.014
stem cell developmentGO:0048864690.014
glycoprotein metabolic processGO:00091001100.014
salivary gland morphogenesisGO:000743540.014
regulation of protein processingGO:00706131500.014
carbohydrate metabolic processGO:00059752070.014
limbic system developmentGO:002176130.014
positive regulation of locomotionGO:00400171860.014
cellular response to organic cyclic compoundGO:00714071270.014
nucleoside triphosphate catabolic processGO:00091433940.014
negative regulation of protein phosphorylationGO:00019331400.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
neural tube formationGO:000184130.014
neuroblast proliferationGO:000740540.014
regulation of protein maturationGO:19033171500.014
response to biotic stimulusGO:00096072760.014
nuclear migrationGO:000709710.014
negative regulation of phosphorylationGO:00423261740.014
cellular response to nitrogen compoundGO:19016991440.014
dephosphorylationGO:00163112090.014
cellular lipid metabolic processGO:00442553030.014
response to axon injuryGO:004867810.014
positive regulation of cell cycleGO:00457871400.014
negative regulation of mitotic cell cycleGO:00459301020.014
positive regulation of kinase activityGO:00336742040.014
somatic stem cell maintenanceGO:003501940.014
positive regulation of hormone biosynthetic processGO:004688640.014
blood vessel morphogenesisGO:00485141620.014
forebrain neuron differentiationGO:002187930.014
response to bacteriumGO:00096171440.013
actin filament organizationGO:00070151280.013
thymus developmentGO:004853830.013
tube closureGO:006060630.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
regulation of neural precursor cell proliferationGO:200017740.013
regulation of chromosome segregationGO:0051983440.013
microtubule based movementGO:0007018320.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
catagenGO:004263730.013
actin filament based movementGO:0030048170.013
regulation of anatomical structure sizeGO:00900661010.013
positive regulation of protein catabolic processGO:0045732750.013
rhythmic behaviorGO:000762220.013
positive regulation of peptidase activityGO:0010952880.013
negative regulation of locomotionGO:00400131180.013
positive regulation of organelle organizationGO:00106381950.013
somitogenesisGO:000175620.013
positive regulation of nucleoside metabolic processGO:00459791860.013
positive regulation of cellular component movementGO:00512721810.013
lipid metabolic processGO:00066293810.013
embryo developmentGO:00097901230.013
response to growth factorGO:00708482050.013
spindle elongationGO:005123140.013
regulation of growthGO:00400081650.013
myeloid cell differentiationGO:00300991170.013
regulation of endopeptidase activityGO:00525481700.013
ion homeostasisGO:00508012300.013
purine ribonucleoside catabolic processGO:00461303980.013
associative learningGO:000830610.013
cell growthGO:00160491600.013
lipid biosynthetic processGO:00086101770.013
small molecule biosynthetic processGO:00442831570.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
innate immune responseGO:00450871780.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
axon cargo transportGO:000808820.013
spermatid developmentGO:000728640.013
regulation of protein transportGO:00512232130.013
retina vasculature development in camera type eyeGO:006129830.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
neural tube closureGO:000184330.013
negative regulation of kinase activityGO:00336731060.013
nucleocytoplasmic transportGO:00069131760.013
positive regulation of neural precursor cell proliferationGO:200017920.013
circadian behaviorGO:004851220.013
regulation of synaptic plasticityGO:004816730.013
i kappab kinase nf kappab signalingGO:00072491660.013
negative regulation of immune system processGO:00026831360.013
t cell differentiation in thymusGO:003307740.013
regulation of epithelial cell proliferationGO:00506781130.012
rna interferenceGO:001624640.012
meiosis iGO:000712740.012
dna conformation changeGO:00711031130.012
sensory perception of smellGO:000760820.012
stem cell differentiationGO:0048863930.012
regulation of response to external stimulusGO:00321012220.012
immune system developmentGO:00025201950.012
cellular response to growth factor stimulusGO:00713631970.012
interspecies interaction between organismsGO:00444191560.012
limb bud formationGO:006017410.012
urogenital system developmentGO:0001655650.012
reproductive structure developmentGO:0048608550.012
myoblast fusionGO:000752010.012
positive regulation of purine nucleotide metabolic processGO:19005442270.012
visual behaviorGO:000763220.012
neurotransmitter secretionGO:000726940.012
behaviorGO:00076101120.012
mitotic cell cycle phase transitionGO:00447721620.012
response to fungusGO:000962040.012
hemopoiesisGO:00300971800.012
peptidyl lysine modificationGO:00182051440.012
response to external biotic stimulusGO:00432072610.012
canonical wnt signaling pathwayGO:00600701160.012
response to hypoxiaGO:0001666960.012
methylationGO:00322591060.012
regulation of nucleotide metabolic processGO:00061402690.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
regulation of wnt signaling pathwayGO:00301111230.012
hormone metabolic processGO:0042445610.012
tissue regenerationGO:004224630.012
negative regulation of cell motilityGO:20001461040.012
metaphase anaphase transition of cell cycleGO:0044784210.012
ectodermal placode developmentGO:007169610.012
dna packagingGO:0006323770.012
organic hydroxy compound metabolic processGO:19016151470.012
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.012
signal transduction by phosphorylationGO:00230142970.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
ossificationGO:00015031210.012
macromolecule methylationGO:0043414970.012
regulation of intracellular transportGO:00323861950.012
guanosine containing compound catabolic processGO:19010692390.012
angiogenesisGO:00015251470.012
negative regulation of gliogenesisGO:001401430.012
tube developmentGO:00352951250.012
negative regulation of cellular component movementGO:00512711060.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of male gonad developmentGO:200001840.012
negative regulation of proteolysisGO:00458611320.012
positive regulation of protein kinase activityGO:00458601900.012
midgut developmentGO:000749410.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
negative regulation of organelle organizationGO:00106391260.012
establishment of protein localization to organelleGO:00725941720.012
positive regulation of proteasomal protein catabolic processGO:1901800350.011
signal transduction by p53 class mediatorGO:0072331720.011
guanosine containing compound metabolic processGO:19010682440.011
positive regulation of aldosterone metabolic processGO:003234620.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
g protein coupled receptor signaling pathwayGO:00071862070.011
chromosome separationGO:0051304230.011
microtubule cytoskeleton organizationGO:00002261760.011
chemical homeostasisGO:00488783060.011
regulation of peptidyl tyrosine phosphorylationGO:00507301080.011
head developmentGO:00603221080.011
regulation of nucleoside metabolic processGO:00091182090.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
intracellular receptor signaling pathwayGO:00305221040.011
histone modificationGO:00165702510.011
hormone secretionGO:0046879650.011
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.011
axis elongationGO:000340140.011
viral life cycleGO:00190581320.011
mrna metabolic processGO:00160711750.011
blood circulationGO:00080151130.011
carboxylic acid biosynthetic processGO:0046394970.011
heart formationGO:006091420.011
regulation of bindingGO:00510981110.011
muscle system processGO:0003012810.011
establishment of planar polarityGO:000173630.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of gtpase activityGO:00430871800.011
regulation of multi organism processGO:00439001570.011
neural crest cell developmentGO:001403230.011
positive regulation of nucleotide metabolic processGO:00459812300.011
establishment of protein localization to membraneGO:00901501210.011
sex determinationGO:000753030.011
negative regulation of growthGO:0045926970.011
gtp metabolic processGO:00460392390.011
regulation of body fluid levelsGO:0050878990.011
developmental process involved in reproductionGO:0003006660.011
regulation of nuclear divisionGO:0051783650.011
lens development in camera type eyeGO:000208820.011
cell migration involved in gastrulationGO:004207410.011
positive regulation of cell migrationGO:00303351720.011
regulation of acrosome reactionGO:006004640.011
response to radiationGO:00093141510.011
positive regulation of cell developmentGO:0010720920.011
regulation of peptidase activityGO:00525471800.011
reactive oxygen species metabolic processGO:0072593750.011
multi organism reproductive processGO:0044703540.011
regulation of cellular protein catabolic processGO:1903362960.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.011

PRAME disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.033
bone diseaseDOID:0080001880.028
connective tissue diseaseDOID:651090.028
sensory system diseaseDOID:00501552030.025
nervous system diseaseDOID:8634310.025
disease of metabolismDOID:00146672950.024
disease of cellular proliferationDOID:145661740.024
cancerDOID:1621670.024
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
inherited metabolic disorderDOID:6552420.018
organ system cancerDOID:00506861640.017
central nervous system diseaseDOID:3311860.017
retinal diseaseDOID:56791180.016
bone development diseaseDOID:0080006550.016
disease of mental healthDOID:150700.012
neurodegenerative diseaseDOID:12891020.011
immune system diseaseDOID:29141550.011