Homo sapiens

0 known processes

PRAM1

PML-RARA regulated adaptor molecule 1

(Aliases: PRAM-1,PML-RAR,MGC39864)

PRAM1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161923710.105
immune responseGO:00069553070.093
cellular ketone metabolic processGO:0042180800.087
cellular amine metabolic processGO:0044106410.075
regulation of protein localizationGO:00328802960.075
regulation of cellular amino acid metabolic processGO:000652160.073
regulation of cellular ketone metabolic processGO:0010565500.071
negative regulation of catalytic activityGO:00430863350.071
post embryonic developmentGO:000979120.067
amine metabolic processGO:0009308440.066
purine nucleoside triphosphate catabolic processGO:00091463920.066
regulation of locomotionGO:00400123290.061
nucleoside triphosphate catabolic processGO:00091433940.059
regulation of immune responseGO:00507762010.056
organophosphate catabolic processGO:00464344300.056
purine ribonucleotide catabolic processGO:00091544040.055
positive regulation of hydrolase activityGO:00513453310.055
negative regulation of phosphate metabolic processGO:00459362670.054
purine ribonucleoside catabolic processGO:00461303980.054
enzyme linked receptor protein signaling pathwayGO:00071673030.053
cytokine productionGO:00018162470.053
nucleotide catabolic processGO:00091664080.053
purine ribonucleoside triphosphate catabolic processGO:00092073910.052
negative regulation of phosphorus metabolic processGO:00105632670.052
negative regulation of protein metabolic processGO:00512483910.051
purine nucleotide catabolic processGO:00061954050.050
secretionGO:00469032540.050
membrane organizationGO:00610242920.050
glycosyl compound catabolic processGO:19016584130.049
nucleoside triphosphate metabolic processGO:00091414220.048
defense responseGO:00069523150.048
positive regulation of immune system processGO:00026842830.048
cell activationGO:00017752130.048
positive regulation of catabolic processGO:00098963100.048
positive regulation of phosphorylationGO:00423273940.047
purine ribonucleoside metabolic processGO:00461284370.046
purine nucleoside triphosphate metabolic processGO:00091444120.046
regulation of cytokine productionGO:00018172320.046
innate immune responseGO:00450871780.046
nucleoside catabolic processGO:00091644080.045
negative regulation of cellular protein metabolic processGO:00322693530.045
ribonucleoside triphosphate catabolic processGO:00092033910.044
regulation of nucleoside metabolic processGO:00091182090.044
small gtpase mediated signal transductionGO:0007264780.044
cellular amino acid metabolic processGO:00065201160.043
ribonucleoside catabolic processGO:00424544060.042
regulation of protein transportGO:00512232130.042
biological adhesionGO:00226103310.042
protein catabolic processGO:00301633250.042
single organism cellular localizationGO:19025803320.041
ribonucleotide catabolic processGO:00092614050.041
purine containing compound catabolic processGO:00725234110.040
nucleoside phosphate catabolic processGO:19012924120.039
negative regulation of cellular component organizationGO:00511292350.039
cell adhesionGO:00071553250.039
protein maturationGO:00516042330.039
regulation of transferase activityGO:00513383550.039
protein processingGO:00164852260.039
regulation of cellular amine metabolic processGO:0033238110.038
chemical homeostasisGO:00488783060.038
multicellular organismal agingGO:001025930.037
positive regulation of immune responseGO:00507781590.037
response to oxygen containing compoundGO:19017003690.036
ribonucleoside triphosphate metabolic processGO:00091994120.035
activation of immune responseGO:00022531140.035
regulation of cell migrationGO:00303342890.035
oogenesisGO:004847720.035
negative regulation of protein processingGO:00109551420.035
regulation of secretion by cellGO:19035301770.034
regulation of i kappab kinase nf kappab signalingGO:00431221620.034
positive regulation of cytokine productionGO:00018191670.034
regulation of mapk cascadeGO:00434082620.034
regulation of nucleotide catabolic processGO:00308112050.034
cell developmentGO:00484683280.033
ras protein signal transductionGO:0007265730.033
locomotory behaviorGO:000762610.033
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.033
regulation of cell motilityGO:20001452990.033
positive regulation of cellular amine metabolic processGO:003324070.033
cellular lipid metabolic processGO:00442553030.033
response to other organismGO:00517072610.032
regulation of cellular component biogenesisGO:00440872810.032
dephosphorylationGO:00163112090.032
cellular protein catabolic processGO:00442572610.032
regulation of anatomical structure morphogenesisGO:00226032860.032
regulation of proteolysisGO:00301622930.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
positive regulation of purine nucleotide metabolic processGO:19005442270.032
guanosine containing compound catabolic processGO:19010692390.031
positive regulation of transportGO:00510503360.031
regulation of vesicle mediated transportGO:00606271300.031
system processGO:00030083490.031
determination of adult lifespanGO:000834020.030
regulation of secretionGO:00510461940.030
regulation of nucleotide metabolic processGO:00061402690.030
single organism membrane organizationGO:00448022680.030
leukocyte activationGO:00453211640.030
cdc42 protein signal transductionGO:003248840.030
negative regulation of hydrolase activityGO:00513461820.030
negative regulation of peptidase activityGO:0010466910.030
regulation of protein kinase activityGO:00458592890.030
negative regulation of protein maturationGO:19033181420.029
nervous system developmentGO:00073992930.029
lipid metabolic processGO:00066293810.029
cytoplasmic transportGO:00164823790.029
negative regulation of cellular amine metabolic processGO:003323930.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
cation transportGO:00068123310.029
regulation of defense responseGO:00313471540.028
cellular response to cytokine stimulusGO:00713451810.028
positive regulation of purine nucleotide catabolic processGO:00331231850.028
positive regulation of nucleotide catabolic processGO:00308131850.028
negative regulation of cellular amino acid metabolic processGO:004576320.028
regulation of protein maturationGO:19033171500.028
female gamete generationGO:000729220.028
actin filament based processGO:00300292240.028
negative regulation of cell deathGO:00605483450.028
negative regulation of protein modification processGO:00314002000.027
response to cytokineGO:00340972320.027
positive regulation of nucleoside metabolic processGO:00459791860.027
regulation of sequence specific dna binding transcription factor activityGO:00510902110.027
rho protein signal transductionGO:0007266260.027
purine nucleoside catabolic processGO:00061523980.027
response to growth factorGO:00708482050.027
regulation of cell cycleGO:00517263930.027
mapk cascadeGO:00001652880.027
positive regulation of protein phosphorylationGO:00019343130.027
cellular component morphogenesisGO:00329893140.027
negative regulation of multicellular organismal processGO:00512413170.027
gtp catabolic processGO:00061842370.026
signal transduction by phosphorylationGO:00230142970.026
gtp metabolic processGO:00460392390.026
regulation of endopeptidase activityGO:00525481700.026
regulation of cell differentiationGO:00455953930.026
positive regulation of gtpase activityGO:00435471660.026
regulation of intracellular transportGO:00323861950.026
secretion by cellGO:00329402260.026
regulation of cell morphogenesisGO:00226041530.026
regulation of purine nucleotide catabolic processGO:00331212050.026
positive regulation of cell proliferationGO:00082843010.026
regulation of cellular component movementGO:00512703340.025
regulation of protein catabolic processGO:00421761550.025
i kappab kinase nf kappab signalingGO:00072491660.025
cellular macromolecule catabolic processGO:00442653800.025
oxidation reduction processGO:00551143960.024
positive regulation of cellular catabolic processGO:00313312840.024
positive regulation of cellular component organizationGO:00511303760.024
transmembrane transportGO:00550853990.024
adult locomotory behaviorGO:000834410.024
positive regulation of protein transportGO:00512221350.024
cellular response to oxygen containing compoundGO:19017012760.024
maintenance of locationGO:00512351120.024
cell morphogenesisGO:00009022960.024
response to external biotic stimulusGO:00432072610.024
cellular response to dna damage stimulusGO:00069743790.024
positive regulation of apoptotic processGO:00430652460.023
response to biotic stimulusGO:00096072760.023
regulation of leukocyte activationGO:00026941150.023
cell projection organizationGO:00300302520.023
regulation of kinase activityGO:00435493140.023
positive regulation of developmental processGO:00510943140.023
lipid biosynthetic processGO:00086101770.023
positive regulation of nucleotide metabolic processGO:00459812300.023
guanosine containing compound metabolic processGO:19010682440.023
negative regulation of developmental processGO:00510932470.023
cytokine secretionGO:0050663640.023
lymphocyte activationGO:00466491330.022
negative regulation of phosphorylationGO:00423261740.022
immune response regulating signaling pathwayGO:0002764970.022
immune effector processGO:00022521590.022
protein localization to membraneGO:00726571600.022
positive regulation of secretion by cellGO:19035321080.022
negative regulation of apoptotic processGO:00430663160.022
positive regulation of transferase activityGO:00513472270.022
actin cytoskeleton organizationGO:00300362070.022
apoptotic signaling pathwayGO:00971902680.022
positive regulation of protein kinase activityGO:00458601900.022
negative regulation of alpha beta t cell activationGO:004663630.021
negative regulation of intracellular signal transductionGO:19025321830.021
regulation of protein processingGO:00706131500.021
regulation of peptidase activityGO:00525471800.021
regulation of establishment of protein localizationGO:00702012420.021
cellular response to endogenous stimulusGO:00714953360.021
negative regulation of proteolysisGO:00458611320.021
positive regulation of proteolysisGO:00458621420.021
immune system developmentGO:00025201950.021
single organism cell adhesionGO:00986021790.021
regulation of cell activationGO:00508651250.021
positive regulation of programmed cell deathGO:00430682490.021
ubiquitin dependent protein catabolic processGO:00065112060.021
negative regulation of immune system processGO:00026831360.021
negative regulation of locomotionGO:00400131180.021
negative regulation of transportGO:00510511760.021
positive regulation of organelle organizationGO:00106381950.021
g protein coupled receptor signaling pathwayGO:00071862070.020
regulation of response to external stimulusGO:00321012220.020
cellular protein complex assemblyGO:00436231880.020
cellular macromolecular complex assemblyGO:00346223240.020
neuromuscular junction developmentGO:000752830.020
regulation of gtp catabolic processGO:00331241800.020
protein secretionGO:0009306980.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
positive regulation of secretionGO:00510471160.020
protein modification by small protein conjugationGO:00324463420.020
hemopoiesisGO:00300971800.020
protein oligomerizationGO:00512591730.020
regulation of innate immune responseGO:0045088970.019
memoryGO:000761330.019
peptidyl tyrosine modificationGO:00182121700.019
ribonucleoside monophosphate metabolic processGO:00091611870.019
endomembrane system organizationGO:00102561960.019
mitotic cell cycleGO:00002783260.019
metal ion transportGO:00300012720.019
protein localization to organelleGO:00333652800.019
regulation of cytokine secretionGO:0050707570.019
neurotransmitter secretionGO:000726940.019
negative regulation of protein phosphorylationGO:00019331400.019
modification dependent protein catabolic processGO:00199412090.019
endocytosisGO:00068971590.019
response to bacteriumGO:00096171440.019
phospholipid metabolic processGO:0006644990.019
positive regulation of cellular component biogenesisGO:00440891580.019
response to axon injuryGO:004867810.018
cellular cation homeostasisGO:00300031630.018
mitotic nuclear divisionGO:00070671190.018
cellular ion homeostasisGO:00068731680.018
regulation of immune effector processGO:0002697910.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
cell cycle phase transitionGO:00447701730.018
cardiovascular system developmentGO:00723582620.018
negative regulation of cell migrationGO:00303361020.018
organophosphate biosynthetic processGO:00904071630.018
positive regulation of cell deathGO:00109422630.018
oocyte differentiationGO:000999420.018
peripheral nervous system developmentGO:000742220.018
cell cell signalingGO:00072671550.018
cytokine mediated signaling pathwayGO:00192211090.018
negative regulation of endopeptidase activityGO:0010951840.018
response to abiotic stimulusGO:00096283360.018
cation transmembrane transportGO:00986552380.018
taxisGO:00423301570.017
regulation of ras protein signal transductionGO:00465781550.017
regulation of gtpase activityGO:00430871800.017
regulation of protein serine threonine kinase activityGO:00719001790.017
small molecule biosynthetic processGO:00442831570.017
regulation of dephosphorylationGO:0035303960.017
protein autophosphorylationGO:00467771230.017
oocyte developmentGO:004859910.017
regulation of response to woundingGO:19030341010.017
regulation of cytoskeleton organizationGO:00514931770.017
single organismal cell cell adhesionGO:00163371480.017
negative regulation of phagocytosisGO:005076540.017
protein ubiquitinationGO:00165673140.017
chromatin modificationGO:00165682980.017
regulation of synaptic plasticityGO:004816730.017
regulation of ras gtpase activityGO:00323181280.017
carbohydrate metabolic processGO:00059752070.017
mitotic cell cycle processGO:19030472860.017
regulation of lipid metabolic processGO:0019216960.017
regulation of cell developmentGO:00602841610.017
positive regulation of innate immune responseGO:0045089790.017
myeloid cell differentiationGO:00300991170.017
monocarboxylic acid metabolic processGO:00327871850.017
segmentationGO:003528240.017
vasodilationGO:004231140.016
negative regulation of programmed cell deathGO:00430693210.016
cellular homeostasisGO:00197251960.016
glycerolipid metabolic processGO:00464861070.016
regulation of phosphatase activityGO:0010921810.016
cell projection assemblyGO:00300311260.016
regenerationGO:003109940.016
positive regulation of gtp catabolic processGO:00331261660.016
positive regulation of ras gtpase activityGO:00323201170.016
associative learningGO:000830610.016
calcium ion transportGO:00068161470.016
negative regulation of complement activation lectin pathwayGO:000186920.016
histone modificationGO:00165702510.016
post embryonic organ developmentGO:004856910.016
detection of stimulusGO:0051606850.016
peptidyl tyrosine phosphorylationGO:00181081700.016
cation homeostasisGO:00550801890.016
single organism carbohydrate metabolic processGO:00447231930.015
leukocyte migrationGO:00509001070.015
regulation of protein secretionGO:0050708860.015
nitrogen compound transportGO:00717051910.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.015
purine containing compound biosynthetic processGO:0072522880.015
covalent chromatin modificationGO:00165692540.015
proteasomal protein catabolic processGO:00104981760.015
circulatory system developmentGO:00723592620.015
positive regulation of cell motilityGO:20001471770.015
positive regulation of mapk cascadeGO:00434101900.015
epithelium developmentGO:00604292270.015
positive regulation of cell migrationGO:00303351720.015
ion transmembrane transportGO:00342203380.015
negative regulation of protein transportGO:0051224750.015
sensory perceptionGO:00076001030.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
organonitrogen compound biosynthetic processGO:19015662000.015
hemostasisGO:0007599760.015
posttranscriptional regulation of gene expressionGO:00106082130.015
response to nitrogen compoundGO:19016981840.015
plasma membrane organizationGO:00070091150.015
microtubule based processGO:00070172100.015
divalent metal ion transportGO:00708381520.015
atp metabolic processGO:00460341760.015
immune response activating signal transductionGO:0002757900.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
regulation of purine nucleotide metabolic processGO:19005422640.014
negative regulation of cellular component movementGO:00512711060.014
regulation of cytoplasmic transportGO:19036491490.014
calcium ion homeostasisGO:00550741220.014
viral processGO:00160321460.014
lipid localizationGO:00108761060.014
hindbrain developmentGO:003090230.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.014
protein homooligomerizationGO:00512601000.014
regulation of ion transportGO:00432691890.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
spermatid differentiationGO:004851540.014
regulation of wound healingGO:0061041560.014
neurological system processGO:00508771630.014
organelle fissionGO:00482851490.014
negative regulation of phosphatase activityGO:0010923610.014
blood circulationGO:00080151130.014
cell substrate adhesionGO:00315891320.014
regulation of cellular response to stressGO:00801352440.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
negative regulation of protein kinase activityGO:0006469980.014
t cell activationGO:0042110990.014
regulation of phagocytosis engulfmentGO:006009920.014
cellular response to growth factor stimulusGO:00713631970.014
metal ion homeostasisGO:00550651690.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
chromatin organizationGO:00063253510.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of t cell activationGO:0050863770.014
positive regulation of protein secretionGO:0050714600.013
blastoderm segmentationGO:000735020.013
fatty acid metabolic processGO:00066311150.013
central nervous system developmentGO:00074171230.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
intracellular protein transportGO:00068862700.013
photoreceptor cell differentiationGO:004653020.013
regulation of endocytosisGO:0030100720.013
anterior posterior axis specificationGO:000994820.013
regulation of cell adhesionGO:00301551660.013
positive regulation of locomotionGO:00400171860.013
regulation of anatomical structure sizeGO:00900661010.013
rab protein signal transductionGO:003248240.013
morphogenesis of embryonic epitheliumGO:001633140.013
cell chemotaxisGO:00603261120.013
cellular metal ion homeostasisGO:00068751460.013
ion homeostasisGO:00508012300.013
negative regulation of cell differentiationGO:00455961710.013
positive regulation of ion transportGO:0043270870.013
intracellular receptor signaling pathwayGO:00305221040.013
microtubule cytoskeleton organizationGO:00002261760.013
glycerophospholipid metabolic processGO:0006650840.013
epithelial cell migrationGO:00106311190.013
regulation of cell cycle processGO:00105642660.013
negative regulation of cell motilityGO:20001461040.013
regulation of cellular protein catabolic processGO:1903362960.013
cellular divalent inorganic cation homeostasisGO:00725031280.013
divalent inorganic cation homeostasisGO:00725071360.013
response to fungusGO:000962040.013
defense response to other organismGO:00985421290.013
vasculature developmentGO:00019441810.012
visual behaviorGO:000763220.012
regulation of protein complex assemblyGO:00432541470.012
response to molecule of bacterial originGO:0002237820.012
organic anion transportGO:00157111030.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of cellular component movementGO:00512721810.012
neuroblast proliferationGO:000740540.012
mitotic cell cycle phase transitionGO:00447721620.012
regulation of growthGO:00400081650.012
compound eye developmentGO:004874910.012
endosomal transportGO:00161971290.012
blood vessel developmentGO:00015681720.012
acylglycerol metabolic processGO:0006639270.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
nucleoside monophosphate catabolic processGO:00091251590.012
response to organonitrogen compoundGO:00102431560.012
positive regulation of defense responseGO:0031349870.012
detection of chemical stimulus involved in sensory perceptionGO:0050907330.012
anion transportGO:00068201610.012
growthGO:00400072020.012
sensory perception of smellGO:000760820.012
regulation of myeloid leukocyte mediated immunityGO:000288640.012
negative regulation of cell proliferationGO:00082852280.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
response to woundingGO:00096111680.012
embryonic epithelial tube formationGO:000183840.012
regulation of multi organism processGO:00439001570.012
organelle assemblyGO:00709251760.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
neuron differentiationGO:00301821380.012
glycerolipid biosynthetic processGO:0045017510.012
negative regulation of secretion by cellGO:1903531520.012
regulation of body fluid levelsGO:0050878990.012
wound healingGO:00420601150.012
regulation of lymphocyte activationGO:00512491030.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
detection of chemical stimulusGO:0009593550.012
spermatid developmentGO:000728640.012
brain developmentGO:0007420970.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
positive regulation of cell differentiationGO:00455972110.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
syncytium formation by plasma membrane fusionGO:000076820.012
embryonic camera type eye developmentGO:003107620.012
lipid catabolic processGO:0016042840.012
somatic stem cell maintenanceGO:003501940.012
cell fate determinationGO:000170930.012
establishment of protein localization to membraneGO:00901501210.011
long term memoryGO:000761620.011
response to transforming growth factor betaGO:0071559940.011
regulation of homeostatic processGO:00328441210.011
neurogenesisGO:00220081690.011
cellular chemical homeostasisGO:00550821800.011
circulatory system processGO:00030131130.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
cellular response to transforming growth factor beta stimulusGO:0071560940.011
nerve developmentGO:002167540.011
ameboidal type cell migrationGO:00016671350.011
interspecies interaction between organismsGO:00444191560.011
negative regulation of secretionGO:0051048580.011
defense response to bacteriumGO:0042742630.011
innate immune response activating signal transductionGO:0002758480.011
peptide metabolic processGO:0006518510.011
positive regulation of cell adhesionGO:0045785840.011
cell cycle g2 m phase transitionGO:0044839430.011
actin filament based movementGO:0030048170.011
outflow tract septum morphogenesisGO:000314840.011
carbohydrate derivative biosynthetic processGO:19011372070.011
cell growthGO:00160491600.011
regulation of transforming growth factor beta receptor signaling pathwayGO:0017015480.011
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.011
divalent inorganic cation transportGO:00725111580.011
rna interferenceGO:001624640.011
generation of neuronsGO:00486991520.011
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
interleukin 1 beta productionGO:0032611220.011
chemotaxisGO:00069351570.011
regulation of apoptotic signaling pathwayGO:20012331750.011
regulation of bindingGO:00510981110.011
response to extracellular stimulusGO:0009991850.011
positive regulation of kinase activityGO:00336742040.011
stem cell divisionGO:001714520.011
regulation of membrane potentialGO:0042391950.011
regulation of cell growthGO:00015581350.011
thymus developmentGO:004853830.011
cell projection morphogenesisGO:00488581290.011
rhythmic behaviorGO:000762220.011
jak stat cascadeGO:0007259460.011
peptidyl lysine modificationGO:00182051440.011
negative regulation of response to external stimulusGO:0032102830.011
motor neuron axon guidanceGO:000804520.011
negative regulation of cytokine productionGO:0001818820.011
reactive oxygen species biosynthetic processGO:190340940.011
regulation of interleukin 1 productionGO:0032652210.011
glycoprotein metabolic processGO:00091001100.011
regulation of chromosome organizationGO:00330441030.011
regulation of cellular response to growth factor stimulusGO:0090287760.011
matingGO:000761810.011
negative regulation of cell cycleGO:00457861930.011
tripartite regional subdivisionGO:000735120.011

PRAM1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.050
central nervous system diseaseDOID:3311860.040
nervous system diseaseDOID:8634310.040
inherited metabolic disorderDOID:6552420.033
sensory system diseaseDOID:00501552030.029
eye and adnexa diseaseDOID:14921500.023
eye diseaseDOID:56141490.023
musculoskeletal system diseaseDOID:172230.021
disease of mental healthDOID:150700.020
cognitive disorderDOID:1561290.020
neurodegenerative diseaseDOID:12891020.019
immune system diseaseDOID:29141550.015
connective tissue diseaseDOID:651090.015
dementiaDOID:1307190.014
alzheimer s diseaseDOID:10652160.014
tauopathyDOID:680160.014
disease of cellular proliferationDOID:145661740.014
retinal diseaseDOID:56791180.013
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
bone diseaseDOID:0080001880.012
cardiovascular system diseaseDOID:12871060.011