Homo sapiens

5 known processes

CLCN5

chloride channel 5

(Aliases: XRN,NPHL2,NPHL1,CLC5,XLRH,DENTS,hCIC-K2,CLCK2,hClC-K2)

CLCN5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.079
cellular amino acid metabolic processGO:00065201160.072
cellular ketone metabolic processGO:0042180800.070
amine metabolic processGO:0009308440.067
cellular amine metabolic processGO:0044106410.063
regulation of cellular amine metabolic processGO:0033238110.062
regulation of cellular ketone metabolic processGO:0010565500.061
regulation of cellular amino acid metabolic processGO:000652160.057
ion transmembrane transportGO:00342203380.057
Human Rat
transmembrane transportGO:00550853990.054
Human Rat
system processGO:00030083490.052
positive regulation of cellular amino acid metabolic processGO:004576430.051
positive regulation of cellular amine metabolic processGO:003324070.049
locomotory behaviorGO:000762610.048
determination of adult lifespanGO:000834020.046
multicellular organismal agingGO:001025930.045
inorganic ion transmembrane transportGO:00986602310.041
Human Rat
lipid metabolic processGO:00066293810.041
cytoplasmic transportGO:00164823790.040
organophosphate catabolic processGO:00464344300.039
cation transportGO:00068123310.038
regulation of cell differentiationGO:00455953930.038
female gamete generationGO:000729220.038
purine ribonucleoside metabolic processGO:00461284370.038
nucleoside catabolic processGO:00091644080.038
purine nucleoside triphosphate metabolic processGO:00091444120.037
cellular component morphogenesisGO:00329893140.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
ras protein signal transductionGO:0007265730.036
purine containing compound catabolic processGO:00725234110.036
nucleoside triphosphate metabolic processGO:00091414220.036
nucleoside phosphate catabolic processGO:19012924120.036
positive regulation of transportGO:00510503360.036
nucleotide catabolic processGO:00091664080.035
small gtpase mediated signal transductionGO:0007264780.035
oogenesisGO:004847720.035
segmentationGO:003528240.035
glycosyl compound catabolic processGO:19016584130.035
ribonucleoside catabolic processGO:00424544060.034
cation transmembrane transportGO:00986552380.034
chemical homeostasisGO:00488783060.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
positive regulation of hydrolase activityGO:00513453310.033
cell morphogenesisGO:00009022960.033
ribonucleotide catabolic processGO:00092614050.033
hindbrain developmentGO:003090230.033
single organism cellular localizationGO:19025803320.032
ribonucleoside triphosphate catabolic processGO:00092033910.032
metal ion transportGO:00300012720.032
negative regulation of protein metabolic processGO:00512483910.032
cellular response to endogenous stimulusGO:00714953360.032
secretionGO:00469032540.032
actin filament based processGO:00300292240.032
positive regulation of cellular component organizationGO:00511303760.032
immune responseGO:00069553070.031
defense responseGO:00069523150.031
cellular lipid metabolic processGO:00442553030.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
nervous system developmentGO:00073992930.031
purine nucleoside catabolic processGO:00061523980.031
anion transportGO:00068201610.031
Human Rat
vesicle mediated transportGO:00161923710.031
nucleoside triphosphate catabolic processGO:00091433940.031
cellular macromolecule catabolic processGO:00442653800.030
ion homeostasisGO:00508012300.030
response to oxygen containing compoundGO:19017003690.030
purine nucleotide catabolic processGO:00061954050.030
membrane organizationGO:00610242920.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
neuromuscular junction developmentGO:000752830.030
anatomical structure formation involved in morphogenesisGO:00486462840.030
single organism membrane organizationGO:00448022680.030
purine ribonucleoside catabolic processGO:00461303980.030
response to abiotic stimulusGO:00096283360.030
negative regulation of catalytic activityGO:00430863350.030
negative regulation of cellular protein metabolic processGO:00322693530.029
positive regulation of catabolic processGO:00098963100.029
regulation of protein localizationGO:00328802960.029
positive regulation of phosphorylationGO:00423273940.029
regulation of cellular component movementGO:00512703340.029
inorganic cation transmembrane transportGO:00986621940.029
protein localization to organelleGO:00333652800.029
biological adhesionGO:00226103310.029
regulation of anatomical structure morphogenesisGO:00226032860.028
regulation of cell cycleGO:00517263930.028
carbohydrate metabolic processGO:00059752070.028
regulation of locomotionGO:00400123290.028
purine ribonucleotide catabolic processGO:00091544040.028
oxidation reduction processGO:00551143960.028
nitrogen compound transportGO:00717051910.028
cardiac muscle cell contractionGO:008600340.028
memoryGO:000761330.027
regenerationGO:003109940.027
intracellular protein transportGO:00068862700.027
cell adhesionGO:00071553250.027
positive regulation of cellular catabolic processGO:00313312840.027
signal transduction by phosphorylationGO:00230142970.027
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.027
cellular response to dna damage stimulusGO:00069743790.027
rho protein signal transductionGO:0007266260.026
cell projection organizationGO:00300302520.026
secretion by cellGO:00329402260.026
morphogenesis of embryonic epitheliumGO:001633140.026
cell developmentGO:00484683280.026
cation homeostasisGO:00550801890.026
negative regulation of multicellular organismal processGO:00512413170.026
cellular macromolecular complex assemblyGO:00346223240.026
negative regulation of phosphorus metabolic processGO:00105632670.026
enzyme linked receptor protein signaling pathwayGO:00071673030.026
mitotic cell cycleGO:00002783260.025
single organism carbohydrate metabolic processGO:00447231930.025
positive regulation of protein phosphorylationGO:00019343130.025
protein catabolic processGO:00301633250.025
negative regulation of phosphate metabolic processGO:00459362670.025
regulation of establishment of protein localizationGO:00702012420.025
cellular homeostasisGO:00197251960.025
anterior posterior axis specificationGO:000994820.025
chromatin organizationGO:00063253510.024
regulation of secretionGO:00510461940.024
positive regulation of developmental processGO:00510943140.024
circadian behaviorGO:004851220.024
regulation of kinase activityGO:00435493140.024
regulation of cell motilityGO:20001452990.024
peripheral nervous system developmentGO:000742220.024
regulation of transferase activityGO:00513383550.023
organic anion transportGO:00157111030.023
regulation of nucleotide metabolic processGO:00061402690.023
blastoderm segmentationGO:000735020.023
regulation of cellular component biogenesisGO:00440872810.023
regulation of purine nucleotide metabolic processGO:19005422640.023
rhythmic behaviorGO:000762220.023
actin filament based movementGO:0030048170.023
mapk cascadeGO:00001652880.023
regulation of proteolysisGO:00301622930.023
regulation of secretion by cellGO:19035301770.023
regulation of protein transportGO:00512232130.022
actin mediated cell contractionGO:0070252120.022
circulatory system developmentGO:00723592620.022
regulation of protein kinase activityGO:00458592890.022
neurological system processGO:00508771630.022
gtp metabolic processGO:00460392390.022
cellular chemical homeostasisGO:00550821800.022
negative regulation of developmental processGO:00510932470.022
regulation of cell cycle processGO:00105642660.022
cellular protein catabolic processGO:00442572610.022
guanosine containing compound metabolic processGO:19010682440.022
positive regulation of cell proliferationGO:00082843010.022
response to external biotic stimulusGO:00432072610.022
response to biotic stimulusGO:00096072760.022
motor neuron axon guidanceGO:000804520.022
dephosphorylationGO:00163112090.022
cardiovascular system developmentGO:00723582620.022
chromatin modificationGO:00165682980.021
small molecule biosynthetic processGO:00442831570.021
regulation of intracellular transportGO:00323861950.021
epithelium developmentGO:00604292270.021
adult locomotory behaviorGO:000834410.021
organ formationGO:004864530.021
guanosine containing compound catabolic processGO:19010692390.021
embryonic epithelial tube formationGO:000183840.021
negative regulation of cellular amine metabolic processGO:003323930.021
photoreceptor cell differentiationGO:004653020.021
oocyte developmentGO:004859910.021
negative regulation of cell proliferationGO:00082852280.021
regulation of nucleoside metabolic processGO:00091182090.021
negative regulation of cell deathGO:00605483450.021
positive regulation of nucleotide metabolic processGO:00459812300.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
cellular response to oxygen containing compoundGO:19017012760.021
regulation of cell migrationGO:00303342890.021
regulation of cytokine productionGO:00018172320.020
apoptotic signaling pathwayGO:00971902680.020
cytokine productionGO:00018162470.020
negative regulation of apoptotic processGO:00430663160.020
response to other organismGO:00517072610.020
innate immune responseGO:00450871780.020
carbohydrate derivative biosynthetic processGO:19011372070.020
posttranscriptional regulation of gene expressionGO:00106082130.020
cell fate determinationGO:000170930.020
covalent chromatin modificationGO:00165692540.020
protein targetingGO:00066051870.020
mitotic cell cycle processGO:19030472860.020
negative regulation of cellular component organizationGO:00511292350.020
organonitrogen compound biosynthetic processGO:19015662000.020
lipid biosynthetic processGO:00086101770.020
cellular cation homeostasisGO:00300031630.020
gtp catabolic processGO:00061842370.020
associative learningGO:000830610.020
regulation of cellular response to stressGO:00801352440.020
release of cytoplasmic sequestered nf kappabGO:000858840.020
histone modificationGO:00165702510.020
regulation of mapk cascadeGO:00434082620.020
monocarboxylic acid metabolic processGO:00327871850.020
oocyte differentiationGO:000999420.020
negative regulation of programmed cell deathGO:00430693210.020
regulation of ion transportGO:00432691890.020
Rat
regulation of response to external stimulusGO:00321012220.020
matingGO:000761810.020
positive regulation of cell deathGO:00109422630.019
maintenance of locationGO:00512351120.019
positive regulation of programmed cell deathGO:00430682490.019
nerve developmentGO:002167540.019
metencephalon developmentGO:002203720.019
organic hydroxy compound metabolic processGO:19016151470.019
protein maturationGO:00516042330.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
cerebellum developmentGO:002154920.019
regulation of nucleotide catabolic processGO:00308112050.019
reactive oxygen species biosynthetic processGO:190340940.019
negative regulation of intracellular signal transductionGO:19025321830.019
positive regulation of apoptotic processGO:00430652460.019
inner ear morphogenesisGO:004247240.019
reactive nitrogen species metabolic processGO:200105730.019
positive regulation of immune system processGO:00026842830.019
compound eye developmentGO:004874910.019
positive regulation of cell differentiationGO:00455972110.019
spermatid differentiationGO:004851540.019
endomembrane system organizationGO:00102561960.019
protein modification by small protein conjugationGO:00324463420.019
protein localization to membraneGO:00726571600.018
response to organic cyclic compoundGO:00140702040.018
specification of organ identityGO:001009230.018
actin cytoskeleton organizationGO:00300362070.018
cellular ion homeostasisGO:00068731680.018
protein processingGO:00164852260.018
microtubule based processGO:00070172100.018
protein ubiquitinationGO:00165673140.018
regulation of purine nucleotide catabolic processGO:00331212050.018
negative regulation of protein modification processGO:00314002000.018
metal ion homeostasisGO:00550651690.018
forebrain generation of neuronsGO:002187230.018
response to cytokineGO:00340972320.018
positive regulation of synaptic transmissionGO:005080640.018
negative regulation of transportGO:00510511760.018
neurotransmitter secretionGO:000726940.018
cellular metal ion homeostasisGO:00068751460.017
regulation of gtpase activityGO:00430871800.017
tripartite regional subdivisionGO:000735120.017
positive regulation of nucleotide catabolic processGO:00308131850.017
regulation of synaptic plasticityGO:004816730.017
monovalent inorganic cation transportGO:00156721280.017
spinal cord developmentGO:002151040.017
regulation of cell adhesionGO:00301551660.017
negative regulation of gliogenesisGO:001401430.017
anterior posterior axis specification embryoGO:000859520.017
cellular protein complex assemblyGO:00436231880.017
regulation of cell developmentGO:00602841610.017
positive regulation of nucleoside metabolic processGO:00459791860.017
negative regulation of cell cycleGO:00457861930.017
spermatid developmentGO:000728640.017
morphogenesis of a polarized epitheliumGO:000173830.017
regulation of gtp catabolic processGO:00331241800.017
response to nitrogen compoundGO:19016981840.017
growthGO:00400072020.017
nuclear transportGO:00511691790.017
response to woundingGO:00096111680.017
positive regulation of organelle organizationGO:00106381950.017
cranial nerve developmentGO:002154540.017
regulation of cell morphogenesisGO:00226041530.017
sequestering of calcium ionGO:0051208170.017
establishment of protein localization to organelleGO:00725941720.017
cell cell signalingGO:00072671550.017
modification dependent macromolecule catabolic processGO:00436322120.017
negative regulation of phosphorylationGO:00423261740.017
nucleocytoplasmic transportGO:00069131760.016
regulation of cytoplasmic transportGO:19036491490.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
positive regulation of gtp catabolic processGO:00331261660.016
negative regulation of hydrolase activityGO:00513461820.016
regulation of multi organism processGO:00439001570.016
cellular response to growth factor stimulusGO:00713631970.016
muscle system processGO:0003012810.016
striated muscle contractionGO:0006941520.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
sensory perception of painGO:001923340.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
proteasomal protein catabolic processGO:00104981760.016
response to fungusGO:000962040.016
cell divisionGO:00513011680.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
immune system developmentGO:00025201950.016
muscle contractionGO:0006936730.016
endosomal transportGO:00161971290.016
organophosphate biosynthetic processGO:00904071630.016
regulation of hormone levelsGO:00108171250.016
wnt signaling pathwayGO:00160551560.016
glycoprotein metabolic processGO:00091001100.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
regulation of immune responseGO:00507762010.016
anion transmembrane transportGO:0098656760.016
Human Rat
limbic system developmentGO:002176130.016
neurogenesisGO:00220081690.016
cardiac muscle contractionGO:0060048340.016
epithelial cell differentiationGO:00308551410.016
short chain fatty acid importGO:001591310.016
ubiquitin dependent protein catabolic processGO:00065112060.016
response to organonitrogen compoundGO:00102431560.016
response to lipidGO:00339932060.016
positive regulation of transferase activityGO:00513472270.016
divalent inorganic cation transportGO:00725111580.016
visual behaviorGO:000763220.016
regulation of cytoskeleton organizationGO:00514931770.016
syncytium formation by plasma membrane fusionGO:000076820.016
positive regulation of gtpase activityGO:00435471660.016
reactive oxygen species metabolic processGO:0072593750.015
cell substrate adhesionGO:00315891320.015
cell growthGO:00160491600.015
single organism cell adhesionGO:00986021790.015
response to axon injuryGO:004867810.015
cell activationGO:00017752130.015
long term memoryGO:000761620.015
urate transportGO:001574730.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
atp metabolic processGO:00460341760.015
fatty acid metabolic processGO:00066311150.015
neuroblast proliferationGO:000740540.015
cell part morphogenesisGO:00329901370.015
positive regulation of kinase activityGO:00336742040.015
response to growth factorGO:00708482050.015
startle responseGO:000196430.015
negative regulation of cell differentiationGO:00455961710.015
regulation of meiotic cell cycleGO:005144540.015
regulation of neural precursor cell proliferationGO:200017740.015
regulation of mitotic cell cycleGO:00073461890.015
positive regulation of protein transportGO:00512221350.015
sensory perception of smellGO:000760820.015
rna processingGO:00063962550.015
neural tube formationGO:000184130.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
somitogenesisGO:000175620.015
divalent inorganic cation homeostasisGO:00725071360.015
establishment of planar polarityGO:000173630.015
nucleoside monophosphate metabolic processGO:00091231910.015
somatic stem cell maintenanceGO:003501940.015
positive regulation of cellular component biogenesisGO:00440891580.015
regulation of ras protein signal transductionGO:00465781550.015
interspecies interaction between organismsGO:00444191560.015
circulatory system processGO:00030131130.015
neuron fate commitmentGO:004866320.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
regulation of protein catabolic processGO:00421761550.015
immune effector processGO:00022521590.015
blood vessel morphogenesisGO:00485141620.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
tissue regenerationGO:004224630.015
divalent metal ion transportGO:00708381520.015
cell projection morphogenesisGO:00488581290.015
salivary gland morphogenesisGO:000743540.015
modification dependent protein catabolic processGO:00199412090.015
positive regulation of mapk cascadeGO:00434101900.015
organelle assemblyGO:00709251760.015
cellular response to cytokine stimulusGO:00713451810.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
heart formationGO:006091420.014
regulation of growthGO:00400081650.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
organic acid biosynthetic processGO:0016053970.014
carboxylic acid biosynthetic processGO:0046394970.014
regulation of membrane potentialGO:0042391950.014
sequestering of metal ionGO:0051238240.014
response to hormoneGO:00097251750.014
microtubule cytoskeleton organizationGO:00002261760.014
hemopoiesisGO:00300971800.014
cell cycle phase transitionGO:00447701730.014
cell projection assemblyGO:00300311260.014
glial cell migrationGO:000834740.014
regulation of protein serine threonine kinase activityGO:00719001790.014
carboxylic acid transportGO:0046942630.014
rna interferenceGO:001624640.014
forelimb morphogenesisGO:003513640.014
alcohol metabolic processGO:00060661140.014
embryonic forelimb morphogenesisGO:003511540.014
generation of neuronsGO:00486991520.014
positive regulation of transcription from rna polymerase ii promoter during mitosisGO:004602210.014
mitochondrion organizationGO:00070051560.014
blood vessel developmentGO:00015681720.014
myoblast fusionGO:000752010.014
primary neural tube formationGO:001402030.014
neural crest cell developmentGO:001403230.014
lung alveolus developmentGO:004828640.014
dna repairGO:00062811980.014
regulation of actin filament based processGO:00329701410.014
central nervous system developmentGO:00074171230.014
regulation of endopeptidase activityGO:00525481700.014
regulation of vesicle mediated transportGO:00606271300.014
regulation of homeostatic processGO:00328441210.014
homeostasis of number of cells in a free living populationGO:004887410.014
multi organism cellular processGO:00447641560.014
regulation of protein complex assemblyGO:00432541470.014
positive regulation of protein kinase activityGO:00458601900.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
regulation of peptidase activityGO:00525471800.014
neuron differentiationGO:00301821380.014
visual learningGO:000854210.014
regulation of ras gtpase activityGO:00323181280.014
regulation of intracellular protein transportGO:00331571230.014
positive regulation of cytokine productionGO:00018191670.014
establishment of protein localization to membraneGO:00901501210.014
angiogenesisGO:00015251470.014
meiosis iGO:000712740.013
regulation of ion transmembrane transportGO:00347651320.013
Rat
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
stem cell divisionGO:001714520.013
protein oligomerizationGO:00512591730.013
positive regulation of secretionGO:00510471160.013
regulation of dna metabolic processGO:00510521530.013
regulation of neurotransmitter secretionGO:004692830.013
response to bacteriumGO:00096171440.013
protein acylationGO:00435431380.013
organic acid transportGO:0015849650.013
peptidyl lysine modificationGO:00182051440.013
positive regulation of locomotionGO:00400171860.013
developmental programmed cell deathGO:001062330.013
somatic muscle developmentGO:000752510.013
peptidyl tyrosine modificationGO:00182121700.013
melanin metabolic processGO:000658210.013
protein autophosphorylationGO:00467771230.013
neuron projection regenerationGO:003110210.013
positive regulation of cell migrationGO:00303351720.013
cellular calcium ion homeostasisGO:00068741170.013
regulation of cell growthGO:00015581350.013
positive regulation of cellular component movementGO:00512721810.013
calcium ion homeostasisGO:00550741220.013
establishment or maintenance of apical basal cell polarityGO:003508820.013
cell morphogenesis involved in differentiationGO:00009041440.013
chemotaxisGO:00069351570.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
protein localization to nucleusGO:00345041360.013
plasma membrane organizationGO:00070091150.013
endocytosisGO:00068971590.013
sleepGO:003043120.013
negative regulation of synaptic transmissionGO:005080520.013
establishment of tissue polarityGO:000716430.013
negative regulation of protein phosphorylationGO:00019331400.013
sodium independent organic anion transportGO:004325220.013
i kappab kinase nf kappab signalingGO:00072491660.013
organ morphogenesisGO:00098871470.013
cellular response to nitrogen compoundGO:19016991440.013
regulation of wnt signaling pathwayGO:00301111230.013
ameboidal type cell migrationGO:00016671350.013
glycerolipid metabolic processGO:00464861070.013
sex determinationGO:000753030.013
negative regulation of immune system processGO:00026831360.013
thymus developmentGO:004853830.013
positive regulation of ras gtpase activityGO:00323201170.013
response to virusGO:00096151260.013
regulation of protein maturationGO:19033171500.013
vasculature developmentGO:00019441810.013
neuron developmentGO:00486661130.013
epidermis morphogenesisGO:004873030.013
peptidyl tyrosine phosphorylationGO:00181081700.013
retinal ganglion cell axon guidanceGO:003129020.013
regulation of reactive oxygen species metabolic processGO:2000377410.012
positive regulation of neural precursor cell proliferationGO:200017920.012
sulfur compound metabolic processGO:00067901010.012
positive regulation of cell motilityGO:20001471770.012
axis elongationGO:000340140.012
defense response to fungusGO:005083240.012
protein importGO:00170381300.012
positive regulation of proteolysisGO:00458621420.012
blood circulationGO:00080151130.012
rab protein signal transductionGO:003248240.012
forebrain neuron differentiationGO:002187930.012
tube closureGO:006060630.012
mitotic cell cycle phase transitionGO:00447721620.012

CLCN5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.046
inherited metabolic disorderDOID:6552420.033
musculoskeletal system diseaseDOID:172230.028
Human
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.027
disease of cellular proliferationDOID:145661740.025
cancerDOID:1621670.024
immune system diseaseDOID:29141550.023
organ system cancerDOID:00506861640.023
central nervous system diseaseDOID:3311860.022
eye diseaseDOID:56141490.020
eye and adnexa diseaseDOID:14921500.020
connective tissue diseaseDOID:651090.017
Human
muscular diseaseDOID:00800001140.016
muscle tissue diseaseDOID:661130.016
cardiovascular system diseaseDOID:12871060.016
bone diseaseDOID:0080001880.016
Human
retinal diseaseDOID:56791180.016
myopathyDOID:4231040.016
neurodegenerative diseaseDOID:12891020.015
hematopoietic system diseaseDOID:741000.015
amino acid metabolic disorderDOID:9252500.013
disease of mental healthDOID:150700.013
brain diseaseDOID:936730.013
retinal degenerationDOID:8466890.012