Homo sapiens

9 known processes

MPL

myeloproliferative leukemia virus oncogene

(Aliases: C-MPL,MPLV,CD110,TPOR)

MPL biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of multicellular organismal processGO:00512413170.202
amine metabolic processGO:0009308440.128
cellular ketone metabolic processGO:0042180800.122
cellular amine metabolic processGO:0044106410.120
regulation of cellular amine metabolic processGO:0033238110.111
regulation of locomotionGO:00400123290.105
vasculature developmentGO:00019441810.097
positive regulation of cellular amino acid metabolic processGO:004576430.094
regulation of cellular amino acid metabolic processGO:000652160.085
cardiovascular system developmentGO:00723582620.074
positive regulation of cellular amine metabolic processGO:003324070.074
negative regulation of developmental processGO:00510932470.073
regulation of cellular component movementGO:00512703340.073
regulation of cell migrationGO:00303342890.072
blood vessel morphogenesisGO:00485141620.071
circulatory system developmentGO:00723592620.067
post embryonic developmentGO:000979120.065
cellular amino acid metabolic processGO:00065201160.062
regulation of cell motilityGO:20001452990.058
cardiac cell fate determinationGO:006091330.055
regulation of cell cycleGO:00517263930.055
negative regulation of cell differentiationGO:00455961710.055
regulation of anatomical structure morphogenesisGO:00226032860.055
anatomical structure formation involved in morphogenesisGO:00486462840.054
chemical homeostasisGO:00488783060.054
negative regulation of cell deathGO:00605483450.052
cellular response to oxygen containing compoundGO:19017012760.050
regulation of cellular ketone metabolic processGO:0010565500.049
somatic stem cell maintenanceGO:003501940.048
carbohydrate derivative biosynthetic processGO:19011372070.048
transmembrane transportGO:00550853990.047
epithelium migrationGO:00901321190.047
regulation of establishment of protein localizationGO:00702012420.046
hindbrain developmentGO:003090230.046
cell fate determinationGO:000170930.045
nervous system developmentGO:00073992930.044
negative regulation of programmed cell deathGO:00430693210.044
regulation of cell differentiationGO:00455953930.044
organ morphogenesisGO:00098871470.043
response to oxygen containing compoundGO:19017003690.042
interleukin 13 secretionGO:007261120.042
positive regulation of phosphorylationGO:00423273940.042
organonitrogen compound biosynthetic processGO:19015662000.042
cellular response to cytokine stimulusGO:00713451810.042
Human
tissue migrationGO:00901301190.042
cation transportGO:00068123310.041
system processGO:00030083490.041
g protein coupled receptor signaling pathwayGO:00071862070.041
coagulationGO:0050817780.041
positive regulation of cell migrationGO:00303351720.041
angiogenesisGO:00015251470.039
regulation of protein localizationGO:00328802960.039
enzyme linked receptor protein signaling pathwayGO:00071673030.038
regulation of response to external stimulusGO:00321012220.038
regenerationGO:003109940.037
cellular response to endogenous stimulusGO:00714953360.037
epithelium developmentGO:00604292270.037
negative regulation of protein metabolic processGO:00512483910.037
positive regulation of cell proliferationGO:00082843010.037
cytokine productionGO:00018162470.037
Mouse
muscle system processGO:0003012810.036
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.036
cation homeostasisGO:00550801890.036
positive regulation of cell motilityGO:20001471770.036
metal ion homeostasisGO:00550651690.036
chromatin organizationGO:00063253510.035
cell morphogenesisGO:00009022960.035
response to lipidGO:00339932060.035
response to cytokineGO:00340972320.035
Human
purine ribonucleoside metabolic processGO:00461284370.034
negative regulation of cell proliferationGO:00082852280.033
response to woundingGO:00096111680.033
regulation of intracellular transportGO:00323861950.033
blood vessel developmentGO:00015681720.033
positive regulation of transportGO:00510503360.033
cellular component morphogenesisGO:00329893140.032
negative regulation of cellular protein metabolic processGO:00322693530.032
response to biotic stimulusGO:00096072760.032
heart developmentGO:0007507950.032
positive regulation of immune system processGO:00026842830.032
multicellular organismal agingGO:001025930.032
positive regulation of developmental processGO:00510943140.032
regulation of male gonad developmentGO:200001840.031
negative regulation of cellular component movementGO:00512711060.031
determination of adult lifespanGO:000834020.031
motor neuron axon guidanceGO:000804520.031
response to abiotic stimulusGO:00096283360.030
secretionGO:00469032540.030
regulation of epithelial cell proliferationGO:00506781130.030
nucleoside triphosphate metabolic processGO:00091414220.030
positive regulation of hydrolase activityGO:00513453310.030
ras protein signal transductionGO:0007265730.030
hemostasisGO:0007599760.030
regulation of epithelial cell migrationGO:0010632930.030
positive regulation of protein transportGO:00512221350.030
endothelial cell migrationGO:0043542860.029
outflow tract septum morphogenesisGO:000314840.029
regulation of cellular component biogenesisGO:00440872810.029
metencephalon developmentGO:002203720.029
cell projection organizationGO:00300302520.029
cytoplasmic transportGO:00164823790.028
epithelial cell migrationGO:00106311190.028
cell developmentGO:00484683280.028
regulation of protein transportGO:00512232130.028
response to growth factorGO:00708482050.028
positive regulation of cellular component movementGO:00512721810.028
canonical wnt signaling pathwayGO:00600701160.028
defense responseGO:00069523150.028
regulation of cell cycle processGO:00105642660.028
negative regulation of apoptotic processGO:00430663160.028
neuromuscular junction developmentGO:000752830.028
regulation of ion transportGO:00432691890.028
blood coagulationGO:0007596760.027
immune system developmentGO:00025201950.027
negative regulation of transportGO:00510511760.027
positive regulation of locomotionGO:00400171860.027
secretion by cellGO:00329402260.027
wnt signaling pathwayGO:00160551560.027
organelle assemblyGO:00709251760.027
divalent inorganic cation homeostasisGO:00725071360.027
regulation of nucleotide metabolic processGO:00061402690.027
segmentationGO:003528240.027
ribonucleotide biosynthetic processGO:0009260810.026
ion homeostasisGO:00508012300.026
cardiac right ventricle morphogenesisGO:000321530.026
regulation of cytokine productionGO:00018172320.026
Mouse
locomotory behaviorGO:000762610.026
mitotic cell cycleGO:00002783260.026
negative regulation of cellular component organizationGO:00511292350.026
regulation of cell developmentGO:00602841610.026
nucleoside phosphate catabolic processGO:19012924120.026
nucleoside phosphate biosynthetic processGO:19012931090.025
biological adhesionGO:00226103310.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
peptidyl tyrosine modificationGO:00182121700.025
negative regulation of protein modification processGO:00314002000.025
negative regulation of apoptotic signaling pathwayGO:2001234970.025
positive regulation of cell cycleGO:00457871400.025
cellular ion homeostasisGO:00068731680.025
apoptotic signaling pathwayGO:00971902680.025
single organism cellular localizationGO:19025803320.025
regulation of secretionGO:00510461940.024
regulation of secretion by cellGO:19035301770.024
ameboidal type cell migrationGO:00016671350.024
cell adhesionGO:00071553250.024
regulation of proteolysisGO:00301622930.024
regulation of hormone levelsGO:00108171250.024
regulation of apoptotic signaling pathwayGO:20012331750.024
nucleotide catabolic processGO:00091664080.024
response to other organismGO:00517072610.024
positive regulation of cytokine productionGO:00018191670.024
positive regulation of cell deathGO:00109422630.024
cellular divalent inorganic cation homeostasisGO:00725031280.024
memoryGO:000761330.024
regulation of body fluid levelsGO:0050878990.024
metal ion transportGO:00300012720.024
epithelial cell differentiationGO:00308551410.023
cellular response to dna damage stimulusGO:00069743790.023
regulation of purine nucleotide metabolic processGO:19005422640.023
cell cell signalingGO:00072671550.023
immune responseGO:00069553070.023
purine nucleoside catabolic processGO:00061523980.023
negative regulation of locomotionGO:00400131180.023
blood circulationGO:00080151130.023
signal transduction by phosphorylationGO:00230142970.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
positive regulation of cellular component organizationGO:00511303760.022
wound healingGO:00420601150.022
negative regulation of phosphorus metabolic processGO:00105632670.022
chromatin modificationGO:00165682980.022
positive regulation of cell developmentGO:0010720920.022
tube developmentGO:00352951250.022
purine nucleotide biosynthetic processGO:0006164840.022
positive regulation of cell differentiationGO:00455972110.022
purine ribonucleoside triphosphate catabolic processGO:00092073910.022
neurological system processGO:00508771630.022
response to external biotic stimulusGO:00432072610.022
cellular homeostasisGO:00197251960.022
organophosphate catabolic processGO:00464344300.022
positive regulation of programmed cell deathGO:00430682490.022
negative regulation of cell cycleGO:00457861930.021
nucleoside catabolic processGO:00091644080.021
positive regulation of protein phosphorylationGO:00019343130.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
purine containing compound catabolic processGO:00725234110.021
regulation of transferase activityGO:00513383550.021
endodermal cell fate specificationGO:000171440.021
regulation of vasculature developmentGO:1901342970.021
positive regulation of secretion by cellGO:19035321080.021
single organism cell adhesionGO:00986021790.021
intracellular protein transportGO:00068862700.021
pituitary gland developmentGO:002198320.021
female gamete generationGO:000729220.021
nucleotide biosynthetic processGO:00091651090.021
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.021
endodermal cell fate commitmentGO:000171140.021
detection of stimulusGO:0051606850.021
oogenesisGO:004847720.020
regulation of immune responseGO:00507762010.020
hemopoiesisGO:00300971800.020
positive regulation of epithelial cell migrationGO:0010634550.020
epithelial cell proliferationGO:00506731280.020
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
response to hormoneGO:00097251750.020
digestive system developmentGO:0055123750.020
second messenger mediated signalingGO:0019932780.020
head developmentGO:00603221080.020
calcium ion homeostasisGO:00550741220.020
regulation of cell morphogenesisGO:00226041530.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
innate immune responseGO:00450871780.019
peptidyl tyrosine phosphorylationGO:00181081700.019
negative regulation of phosphate metabolic processGO:00459362670.019
stem cell differentiationGO:0048863930.019
purine nucleotide catabolic processGO:00061954050.019
nucleoside triphosphate catabolic processGO:00091433940.019
astrocyte differentiationGO:004870840.019
sex determinationGO:000753030.019
cell morphogenesis involved in differentiationGO:00009041440.019
cell divisionGO:00513011680.019
negative regulation of catalytic activityGO:00430863350.019
regulation of endopeptidase activityGO:00525481700.019
posttranscriptional regulation of gene expressionGO:00106082130.019
organophosphate biosynthetic processGO:00904071630.019
interspecies interaction between organismsGO:00444191560.019
embryonic forelimb morphogenesisGO:003511540.019
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.019
mapk cascadeGO:00001652880.019
regulation of nervous system developmentGO:0051960880.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
cellular response to nitrogen compoundGO:19016991440.018
vesicle mediated transportGO:00161923710.018
membrane organizationGO:00610242920.018
negative regulation of transforming growth factor beta productionGO:007163540.018
negative regulation of cell migrationGO:00303361020.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
small gtpase mediated signal transductionGO:0007264780.018
cardiac muscle cell contractionGO:008600340.018
leukocyte differentiationGO:0002521980.018
cellular response to growth factor stimulusGO:00713631970.018
inorganic cation transmembrane transportGO:00986621940.018
lipid metabolic processGO:00066293810.018
cellular macromolecule catabolic processGO:00442653800.018
cellular calcium ion homeostasisGO:00068741170.018
glycosyl compound catabolic processGO:19016584130.018
cell projection assemblyGO:00300311260.018
basophil differentiationGO:003022120.018
positive regulation of catabolic processGO:00098963100.018
purine ribonucleoside catabolic processGO:00461303980.018
positive regulation of apoptotic processGO:00430652460.018
neurogenesisGO:00220081690.018
regulation of wnt signaling pathwayGO:00301111230.018
gland developmentGO:0048732480.017
protein modification by small protein conjugationGO:00324463420.017
cellular chemical homeostasisGO:00550821800.017
blastoderm segmentationGO:000735020.017
response to radiationGO:00093141510.017
digestive tract developmentGO:0048565750.017
positive regulation of nucleotide metabolic processGO:00459812300.017
oxidation reduction processGO:00551143960.017
cation transmembrane transportGO:00986552380.017
protein acylationGO:00435431380.017
purine ribonucleotide catabolic processGO:00091544040.017
divalent metal ion transportGO:00708381520.017
ion transmembrane transportGO:00342203380.017
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of neural precursor cell proliferationGO:200017740.017
regulation of cytoplasmic transportGO:19036491490.017
regulation of growthGO:00400081650.017
regulation of ion transmembrane transporter activityGO:0032412720.017
regulation of protein complex assemblyGO:00432541470.016
single organism membrane organizationGO:00448022680.016
negative regulation of gliogenesisGO:001401430.016
spermatid differentiationGO:004851540.016
nucleocytoplasmic transportGO:00069131760.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
purine ribonucleotide biosynthetic processGO:0009152790.016
cellular response to organonitrogen compoundGO:00714171240.016
neuron differentiationGO:00301821380.016
regulation of mitotic cell cycleGO:00073461890.016
protein ubiquitinationGO:00165673140.016
cerebellum developmentGO:002154920.016
protein localization to organelleGO:00333652800.016
protein catabolic processGO:00301633250.016
actin mediated cell contractionGO:0070252120.016
regulation of metal ion transportGO:00109591200.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
purine containing compound biosynthetic processGO:0072522880.016
actin filament based movementGO:0030048170.016
positive regulation of kinase activityGO:00336742040.016
tube morphogenesisGO:0035239950.016
regulation of peptidyl tyrosine phosphorylationGO:00507301080.016
ribonucleoside catabolic processGO:00424544060.016
actin filament based processGO:00300292240.016
mitotic cell cycle processGO:19030472860.016
cellular lipid metabolic processGO:00442553030.016
viral processGO:00160321460.016
regulation of interleukin 5 secretionGO:200066220.016
regulation of thyroid hormone generationGO:200060920.016
limbic system developmentGO:002176130.016
response to organic cyclic compoundGO:00140702040.016
cardiac ventricle formationGO:000321120.016
protein targetingGO:00066051870.016
protein acetylationGO:00064731160.016
positive regulation of transferase activityGO:00513472270.016
calcium ion transportGO:00068161470.016
cell activationGO:00017752130.016
positive regulation of purine nucleotide catabolic processGO:00331231850.015
regulation of transmembrane transporter activityGO:0022898740.015
aortic valve developmentGO:000317630.015
regulation of cyclic nucleotide biosynthetic processGO:0030802490.015
action potentialGO:0001508340.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.015
symbiosis encompassing mutualism through parasitismGO:00444031560.015
regulation of kinase activityGO:00435493140.015
growthGO:00400072020.015
multi organism cellular processGO:00447641560.015
regulation of peptidase activityGO:00525471800.015
cell cycle phase transitionGO:00447701730.015
adult locomotory behaviorGO:000834410.015
formation of primary germ layerGO:0001704420.015
sequestering of calcium ionGO:0051208170.015
regulation of cell morphogenesis involved in differentiationGO:0010769830.015
organ formationGO:004864530.015
response to axon injuryGO:004867810.015
forebrain neuron differentiationGO:002187930.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.015
regulation of response to woundingGO:19030341010.015
reproductive processGO:00224141060.015
negative regulation of phosphorylationGO:00423261740.015
regulation of defense responseGO:00313471540.015
ribonucleotide catabolic processGO:00092614050.015
mitotic cell cycle phase transitionGO:00447721620.015
epidermis morphogenesisGO:004873030.015
neuroblast proliferationGO:000740540.015
cellular macromolecular complex assemblyGO:00346223240.015
embryonic hemopoiesisGO:003516240.014
immune effector processGO:00022521590.014
embryonic camera type eye formationGO:006090020.014
central nervous system developmentGO:00074171230.014
endoderm formationGO:0001706330.014
regulation of protein kinase activityGO:00458592890.014
regulation of homeostatic processGO:00328441210.014
ribonucleoprotein complex biogenesisGO:00226131160.014
protein processingGO:00164852260.014
regulation of protein secretionGO:0050708860.014
trophectodermal cell differentiationGO:000182930.014
oocyte developmentGO:004859910.014
cellular modified amino acid metabolic processGO:0006575640.014
response to hypoxiaGO:0001666960.014
positive regulation of synaptic transmissionGO:005080640.014
regulation of transmembrane transportGO:00347621390.014
positive regulation of cellular catabolic processGO:00313312840.014
response to organonitrogen compoundGO:00102431560.014
positive regulation of secretionGO:00510471160.014
ribose phosphate biosynthetic processGO:0046390820.014
cellular metal ion homeostasisGO:00068751460.014
cytokine mediated signaling pathwayGO:00192211090.014
Human
peripheral nervous system developmentGO:000742220.014
matingGO:000761810.014
cyclic nucleotide biosynthetic processGO:0009190610.014
embryonic camera type eye developmentGO:003107620.014
salivary gland morphogenesisGO:000743540.014
regulation of synaptic plasticityGO:004816730.014
positive regulation of proteolysisGO:00458621420.014
negative regulation of intracellular signal transductionGO:19025321830.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
negative regulation of cell motilityGO:20001461040.014
camp metabolic processGO:0046058610.014
sleepGO:003043120.014
nitrogen compound transportGO:00717051910.014
negative regulation of immune system processGO:00026831360.014
spermatid developmentGO:000728640.014
regulation of multi organism processGO:00439001570.014
single organism reproductive processGO:0044702980.014
response to virusGO:00096151260.014
maintenance of locationGO:00512351120.014
sulfur compound metabolic processGO:00067901010.014
small molecule biosynthetic processGO:00442831570.014
epithelial cell developmentGO:0002064340.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
regulation of canonical wnt signaling pathwayGO:0060828880.014
development of primary male sexual characteristicsGO:0046546230.014
compound eye developmentGO:004874910.013
dephosphorylationGO:00163112090.013
response to decreased oxygen levelsGO:0036293960.013
organic acid biosynthetic processGO:0016053970.013
brain developmentGO:0007420970.013
nuclear transportGO:00511691790.013
monocarboxylic acid metabolic processGO:00327871850.013
microtubule based processGO:00070172100.013
rhythmic behaviorGO:000762220.013
cellular response to transforming growth factor beta stimulusGO:0071560940.013
cyclic purine nucleotide metabolic processGO:0052652600.013
establishment of protein localization to organelleGO:00725941720.013
glial cell migrationGO:000834740.013
positive regulation of male gonad developmentGO:200002030.013
response to nitrogen compoundGO:19016981840.013
regulation of meiotic cell cycleGO:005144540.013
positive regulation of cell cycle processGO:00900681060.013
response to oxygen levelsGO:00704821000.013
skin developmentGO:0043588760.013
inner ear morphogenesisGO:004247240.013
visual behaviorGO:000763220.013
reactive oxygen species biosynthetic processGO:190340940.013
pharynx developmentGO:006046510.013
regulation of ion transmembrane transportGO:00347651320.013
regulation of nucleotide catabolic processGO:00308112050.013
negative regulation of cell cycle processGO:00109481210.013
regulation of cellular response to stressGO:00801352440.013
renal system developmentGO:0072001630.013
anterior posterior axis specificationGO:000994820.013
negative regulation of epithelial cell proliferationGO:0050680480.013
cell proliferation in forebrainGO:002184610.013
regulation of protein ubiquitinationGO:0031396950.013
carboxylic acid biosynthetic processGO:0046394970.013
oocyte differentiationGO:000999420.013
nucleoside monophosphate metabolic processGO:00091231910.013
peptidyl lysine acetylationGO:00183941010.013
gtp catabolic processGO:00061842370.013
cerebral cortex cell migrationGO:002179530.013
covalent chromatin modificationGO:00165692540.013
chemotaxisGO:00069351570.013
positive regulation of neurogenesisGO:0050769490.013
cell part morphogenesisGO:00329901370.013
positive regulation of cellular component biogenesisGO:00440891580.013
positive regulation of peptidase activityGO:0010952880.012
sequestering of metal ionGO:0051238240.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
positive regulation of protein kinase activityGO:00458601900.012
protein importGO:00170381300.012
regulation of interleukin 13 secretionGO:200066520.012
ribonucleoprotein complex subunit organizationGO:0071826810.012
cytosolic calcium ion homeostasisGO:0051480890.012
glycoprotein metabolic processGO:00091001100.012
urogenital system developmentGO:0001655650.012
taxisGO:00423301570.012
proteasomal protein catabolic processGO:00104981760.012
regulation of neurogenesisGO:0050767820.012
endochondral bone morphogenesisGO:006035030.012
regulation of membrane potentialGO:0042391950.012
inorganic ion transmembrane transportGO:00986602310.012
striated muscle contractionGO:0006941520.012
regulation of cyclic nucleotide metabolic processGO:0030799630.012
photoreceptor cell differentiationGO:004653020.012
cartilage condensationGO:000150210.012
eosinophil differentiationGO:003022220.012
protein secretionGO:0009306980.012
neuron projection regenerationGO:003110210.012
regulation of purine nucleotide catabolic processGO:00331212050.012
anion transportGO:00068201610.012
cellular cation homeostasisGO:00300031630.012
cellular response to hormone stimulusGO:00328701250.012
embryo developmentGO:00097901230.012
response to metal ionGO:0010038840.012
circadian behaviorGO:004851220.012
cardiac muscle contractionGO:0060048340.012
cell growthGO:00160491600.012
cytokine secretionGO:0050663640.012
response to inorganic substanceGO:00100351270.012
prostate gland developmentGO:003085030.012
neuron developmentGO:00486661130.012
intracellular receptor signaling pathwayGO:00305221040.012
regulation of angiogenesisGO:0045765920.012
regulation of protein stabilityGO:0031647870.012
regulation of transporter activityGO:0032409820.012
reactive oxygen species metabolic processGO:0072593750.012
positive regulation of nucleoside metabolic processGO:00459791860.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of ras gtpase activityGO:00323181280.012
regulation of mapk cascadeGO:00434082620.012
mitochondrion organizationGO:00070051560.012
cardiac chamber formationGO:000320720.012
histone modificationGO:00165702510.012
negative regulation of cell developmentGO:0010721480.012

MPL disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.070
nervous system diseaseDOID:8634310.042
sensory system diseaseDOID:00501552030.042
disease of metabolismDOID:00146672950.041
eye diseaseDOID:56141490.038
eye and adnexa diseaseDOID:14921500.038
retinal diseaseDOID:56791180.028
hematopoietic system diseaseDOID:741000.028
primary ciliary dyskinesiaDOID:9562270.027
disease of cellular proliferationDOID:145661740.022
cancerDOID:1621670.022
retinal degenerationDOID:8466890.018
organ system cancerDOID:00506861640.017
inherited metabolic disorderDOID:6552420.014
central nervous system diseaseDOID:3311860.014
connective tissue diseaseDOID:651090.013
musculoskeletal system diseaseDOID:172230.013