Homo sapiens

6 known processes

SIM1

single-minded homolog 1 (Drosophila)

(Aliases: bHLHe14)

SIM1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.176
transmembrane transportGO:00550853990.175
ion transmembrane transportGO:00342203380.141
organ morphogenesisGO:00098871470.134
cation transportGO:00068123310.132
circulatory system developmentGO:00723592620.118
locomotory behaviorGO:000762610.108
Fly
regulation of cellular component movementGO:00512703340.107
negative regulation of multicellular organismal processGO:00512413170.107
anatomical structure formation involved in morphogenesisGO:00486462840.104
post embryonic developmentGO:000979120.101
amine metabolic processGO:0009308440.098
cellular ketone metabolic processGO:0042180800.098
regulation of cell differentiationGO:00455953930.093
regulation of cellular ketone metabolic processGO:0010565500.090
regulation of cellular amine metabolic processGO:0033238110.089
regulation of locomotionGO:00400123290.089
hindbrain developmentGO:003090230.087
inorganic cation transmembrane transportGO:00986621940.086
cellular amine metabolic processGO:0044106410.084
chemical homeostasisGO:00488783060.082
regulation of cellular amino acid metabolic processGO:000652160.082
neuron fate commitmentGO:004866320.082
muscle system processGO:0003012810.081
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.081
nervous system developmentGO:00073992930.080
Zebrafish Fly
ion homeostasisGO:00508012300.075
cellular amino acid metabolic processGO:00065201160.074
cell developmentGO:00484683280.072
Zebrafish Fly
cation transmembrane transportGO:00986552380.072
cardiovascular system developmentGO:00723582620.070
regulation of anatomical structure morphogenesisGO:00226032860.070
positive regulation of cellular amino acid metabolic processGO:004576430.069
regulation of cell motilityGO:20001452990.067
inorganic ion transmembrane transportGO:00986602310.066
response to oxygen containing compoundGO:19017003690.064
muscle contractionGO:0006936730.064
regulation of system processGO:00440571010.064
metal ion transportGO:00300012720.064
cellular response to endogenous stimulusGO:00714953360.063
specification of organ identityGO:001009230.063
cranial nerve developmentGO:002154540.060
regulation of hormone levelsGO:00108171250.060
negative regulation of developmental processGO:00510932470.060
positive regulation of developmental processGO:00510943140.060
secretion by cellGO:00329402260.059
forebrain regionalizationGO:002187130.059
cell cell signalingGO:00072671550.059
extraocular skeletal muscle developmentGO:000207410.059
nucleoside phosphate catabolic processGO:19012924120.057
segmentationGO:003528240.057
cell morphogenesisGO:00009022960.057
Zebrafish Fly
tissue morphogenesisGO:0048729960.057
epithelium developmentGO:00604292270.056
Mouse
vasculature developmentGO:00019441810.055
secretionGO:00469032540.055
forelimb morphogenesisGO:003513640.054
response to abiotic stimulusGO:00096283360.054
Human
organophosphate catabolic processGO:00464344300.053
cardiac muscle cell contractionGO:008600340.053
actin filament based processGO:00300292240.053
purine containing compound catabolic processGO:00725234110.052
regulation of cell migrationGO:00303342890.051
organ formationGO:004864530.051
anion transportGO:00068201610.051
ribonucleoside triphosphate catabolic processGO:00092033910.050
cation homeostasisGO:00550801890.049
actin filament based movementGO:0030048170.048
nucleoside triphosphate metabolic processGO:00091414220.048
cytoplasmic transportGO:00164823790.047
blood circulationGO:00080151130.047
positive regulation of cellular amine metabolic processGO:003324070.046
purine nucleotide catabolic processGO:00061954050.046
metal ion homeostasisGO:00550651690.046
calcium ion homeostasisGO:00550741220.046
cellular component morphogenesisGO:00329893140.046
Zebrafish Fly
purine ribonucleoside triphosphate metabolic processGO:00092054110.046
regulation of ion transmembrane transportGO:00347651320.046
negative regulation of cell differentiationGO:00455961710.046
regulation of ion transportGO:00432691890.046
glycosyl compound catabolic processGO:19016584130.045
purine ribonucleotide catabolic processGO:00091544040.045
embryonic forelimb morphogenesisGO:003511540.045
cell projection organizationGO:00300302520.044
Zebrafish Fly
cellular homeostasisGO:00197251960.044
positive regulation of cell proliferationGO:00082843010.043
ribonucleoside catabolic processGO:00424544060.043
regulation of cell cycleGO:00517263930.043
ribonucleotide catabolic processGO:00092614050.042
negative regulation of protein metabolic processGO:00512483910.042
nucleoside catabolic processGO:00091644080.042
cellular ion homeostasisGO:00068731680.041
regulation of membrane potentialGO:0042391950.041
spinal cord developmentGO:002151040.041
purine nucleoside triphosphate metabolic processGO:00091444120.041
purine nucleoside triphosphate catabolic processGO:00091463920.041
ribonucleoside triphosphate metabolic processGO:00091994120.041
nucleotide catabolic processGO:00091664080.040
blood vessel developmentGO:00015681720.040
purine ribonucleoside metabolic processGO:00461284370.040
nucleoside triphosphate catabolic processGO:00091433940.040
memoryGO:000761330.040
positive regulation of transportGO:00510503360.040
skeletal system developmentGO:0001501790.040
enzyme linked receptor protein signaling pathwayGO:00071673030.040
central nervous system developmentGO:00074171230.040
Zebrafish Fly
positive regulation of apoptotic processGO:00430652460.039
limbic system developmentGO:002176130.039
Zebrafish
positive regulation of cellular component organizationGO:00511303760.039
female gamete generationGO:000729220.039
biological adhesionGO:00226103310.039
cellular cation homeostasisGO:00300031630.039
cellular divalent inorganic cation homeostasisGO:00725031280.039
positive regulation of synaptic transmissionGO:005080640.038
neuron differentiationGO:00301821380.038
Zebrafish Fly
regulation of secretion by cellGO:19035301770.038
actin mediated cell contractionGO:0070252120.038
cellular chemical homeostasisGO:00550821800.038
nerve developmentGO:002167540.038
ras protein signal transductionGO:0007265730.038
single organism cellular localizationGO:19025803320.038
cellular metal ion homeostasisGO:00068751460.037
negative regulation of programmed cell deathGO:00430693210.037
negative regulation of cell deathGO:00605483450.037
membrane organizationGO:00610242920.037
somatic stem cell maintenanceGO:003501940.037
divalent inorganic cation homeostasisGO:00725071360.037
oogenesisGO:004847720.037
positive regulation of catabolic processGO:00098963100.036
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
positive regulation of cell deathGO:00109422630.036
negative regulation of cellular protein metabolic processGO:00322693530.036
multicellular organismal agingGO:001025930.036
regulation of secretionGO:00510461940.036
nitrogen compound transportGO:00717051910.035
response to nitrogen compoundGO:19016981840.035
regulation of protein transportGO:00512232130.035
divalent inorganic cation transportGO:00725111580.035
purine ribonucleoside catabolic processGO:00461303980.035
positive regulation of programmed cell deathGO:00430682490.035
positive regulation of phosphorylationGO:00423273940.035
embryonic morphogenesisGO:0048598850.035
neurological system processGO:00508771630.035
protein localization to organelleGO:00333652800.035
monovalent inorganic cation transportGO:00156721280.034
positive regulation of cell differentiationGO:00455972110.034
brain developmentGO:0007420970.034
Zebrafish Fly
growthGO:00400072020.034
negative regulation of apoptotic processGO:00430663160.034
cellular response to oxygen containing compoundGO:19017012760.034
adult locomotory behaviorGO:000834410.033
Fly
small gtpase mediated signal transductionGO:0007264780.033
regulation of protein localizationGO:00328802960.033
hematopoietic or lymphoid organ developmentGO:00485341860.033
purine nucleoside catabolic processGO:00061523980.033
regulation of nucleotide metabolic processGO:00061402690.032
positive regulation of nucleotide metabolic processGO:00459812300.032
neurogenesisGO:00220081690.032
Zebrafish Fly
cardiac muscle contractionGO:0060048340.032
head developmentGO:00603221080.032
Zebrafish Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.032
regulation of acrosome reactionGO:006004640.031
generation of neuronsGO:00486991520.031
Zebrafish Fly
positive regulation of cell migrationGO:00303351720.031
stem cell differentiationGO:0048863930.031
single organism carbohydrate metabolic processGO:00447231930.030
mitotic cell cycleGO:00002783260.030
metencephalon developmentGO:002203720.030
cellular calcium ion homeostasisGO:00068741170.030
regulation of establishment of protein localizationGO:00702012420.030
striated muscle tissue developmentGO:0014706590.030
divalent metal ion transportGO:00708381520.029
determination of adult lifespanGO:000834020.029
startle responseGO:000196430.029
regulation of synaptic plasticityGO:004816730.029
positive regulation of cellular catabolic processGO:00313312840.029
positive regulation of hydrolase activityGO:00513453310.029
regulation of cell developmentGO:00602841610.029
negative regulation of catalytic activityGO:00430863350.029
intracellular protein transportGO:00068862700.029
regulation of cytokine productionGO:00018172320.029
positive regulation of cellular component movementGO:00512721810.029
response to organic cyclic compoundGO:00140702040.029
regenerationGO:003109940.029
positive regulation of purine nucleotide catabolic processGO:00331231850.029
peripheral nervous system developmentGO:000742220.028
positive regulation of protein phosphorylationGO:00019343130.028
positive regulation of cell motilityGO:20001471770.028
response to organonitrogen compoundGO:00102431560.028
wnt signaling pathwayGO:00160551560.028
neuromuscular junction developmentGO:000752830.028
defense responseGO:00069523150.028
organonitrogen compound biosynthetic processGO:19015662000.028
cell fate determinationGO:000170930.028
cell morphogenesis involved in differentiationGO:00009041440.028
Zebrafish Fly
behaviorGO:00076101120.028
Fly
regulation of nucleoside metabolic processGO:00091182090.028
vesicle mediated transportGO:00161923710.027
mapk cascadeGO:00001652880.027
blood vessel morphogenesisGO:00485141620.027
angiogenesisGO:00015251470.027
regulation of blood circulationGO:1903522590.027
regulation of nucleotide catabolic processGO:00308112050.027
immune responseGO:00069553070.027
morphogenesis of embryonic epitheliumGO:001633140.027
cellular lipid metabolic processGO:00442553030.027
cellular response to dna damage stimulusGO:00069743790.027
carbohydrate metabolic processGO:00059752070.027
muscle structure developmentGO:0061061980.027
positive regulation of nucleotide catabolic processGO:00308131850.027
cellular response to nitrogen compoundGO:19016991440.027
regulation of purine nucleotide catabolic processGO:00331212050.027
glial cell migrationGO:000834740.027
striated muscle contractionGO:0006941520.027
negative regulation of phosphate metabolic processGO:00459362670.026
lipid metabolic processGO:00066293810.026
regulation of kinase activityGO:00435493140.026
regulation of cell cycle processGO:00105642660.026
immune system developmentGO:00025201950.026
heart morphogenesisGO:0003007480.026
negative regulation of phosphorus metabolic processGO:00105632670.026
guanosine containing compound metabolic processGO:19010682440.026
signal transduction by phosphorylationGO:00230142970.026
regulation of cellular component biogenesisGO:00440872810.026
calcium ion transportGO:00068161470.026
motor neuron axon guidanceGO:000804520.025
regulation of purine nucleotide metabolic processGO:19005422640.025
tube morphogenesisGO:0035239950.025
regulation of actin filament based processGO:00329701410.025
cellular response to growth factor stimulusGO:00713631970.025
blastoderm segmentationGO:000735020.025
cytokine productionGO:00018162470.025
inner ear morphogenesisGO:004247240.025
regulation of proteolysisGO:00301622930.025
positive regulation of hormone biosynthetic processGO:004688640.025
sensory perception of painGO:001923340.024
cerebellum developmentGO:002154920.024
rho protein signal transductionGO:0007266260.024
cellular response to organonitrogen compoundGO:00714171240.024
g protein coupled receptor signaling pathwayGO:00071862070.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of nucleoside metabolic processGO:00459791860.024
response to woundingGO:00096111680.024
regulation of wnt signaling pathwayGO:00301111230.024
protein targetingGO:00066051870.024
carbohydrate derivative biosynthetic processGO:19011372070.024
positive regulation of locomotionGO:00400171860.024
protein localization to nucleusGO:00345041360.024
tube developmentGO:00352951250.024
Mouse
stem cell developmentGO:0048864690.024
multicellular organismal response to stressGO:003355510.024
cytosolic calcium ion homeostasisGO:0051480890.024
regulation of response to external stimulusGO:00321012220.024
cellular macromolecular complex assemblyGO:00346223240.023
cellular macromolecule catabolic processGO:00442653800.023
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.023
circulatory system processGO:00030131130.023
muscle tissue developmentGO:0060537620.023
nuclear transportGO:00511691790.023
negative regulation of protein modification processGO:00314002000.023
cell adhesionGO:00071553250.023
protein oligomerizationGO:00512591730.023
positive regulation of immune system processGO:00026842830.023
response to external biotic stimulusGO:00432072610.023
protein catabolic processGO:00301633250.023
associative learningGO:000830610.023
regulation of intracellular transportGO:00323861950.022
negative regulation of cell proliferationGO:00082852280.022
regulation of transferase activityGO:00513383550.022
chromatin organizationGO:00063253510.022
nucleocytoplasmic transportGO:00069131760.022
regulation of protein kinase activityGO:00458592890.022
response to lipidGO:00339932060.022
regulation of muscle system processGO:0090257530.022
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.022
mitotic cell cycle processGO:19030472860.022
regulation of sequence specific dna binding transcription factor activityGO:00510902110.022
cardiac right ventricle morphogenesisGO:000321530.022
regulation of transmembrane transportGO:00347621390.021
response to cytokineGO:00340972320.021
negative regulation of transportGO:00510511760.021
cell projection morphogenesisGO:00488581290.021
Zebrafish Fly
chemotaxisGO:00069351570.021
Zebrafish Fly
response to biotic stimulusGO:00096072760.021
protein maturationGO:00516042330.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
guanosine containing compound catabolic processGO:19010692390.021
neuron projection developmentGO:00311751060.021
Zebrafish Fly
regulation of gtp catabolic processGO:00331241800.021
response to other organismGO:00517072610.021
sequestering of calcium ionGO:0051208170.021
regulation of cell adhesionGO:00301551660.021
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.021
regulation of mitotic cell cycleGO:00073461890.021
regulation of cytoplasmic transportGO:19036491490.021
embryo developmentGO:00097901230.021
establishment of protein localization to organelleGO:00725941720.021
single organism membrane organizationGO:00448022680.021
regulation of canonical wnt signaling pathwayGO:0060828880.021
potassium ion transmembrane transportGO:0071805600.021
cellular response to cytokine stimulusGO:00713451810.021
response to hormoneGO:00097251750.021
gtp catabolic processGO:00061842370.021
purine ribonucleoside monophosphate metabolic processGO:00091671860.021
positive regulation of secretionGO:00510471160.020
negative regulation of cellular amine metabolic processGO:003323930.020
embryonic epithelial tube formationGO:000183840.020
matingGO:000761810.020
negative regulation of cellular component organizationGO:00511292350.020
response to growth factorGO:00708482050.020
hemopoiesisGO:00300971800.020
ribonucleoside monophosphate metabolic processGO:00091611870.020
single organism cell adhesionGO:00986021790.020
positive regulation of gtp catabolic processGO:00331261660.020
sodium ion transmembrane transportGO:0035725590.020
lipid biosynthetic processGO:00086101770.020
negative regulation of phosphorylationGO:00423261740.020
positive regulation of cellular component biogenesisGO:00440891580.020
endomembrane system organizationGO:00102561960.020
anterior posterior axis specificationGO:000994820.020
heart formationGO:006091420.020
heart developmentGO:0007507950.020
muscle organ developmentGO:0007517560.020
compound eye developmentGO:004874910.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
positive regulation of acrosome reactionGO:200034440.020
androgen biosynthetic processGO:000670230.020
regulation of homeostatic processGO:00328441210.019
cell growthGO:00160491600.019
cell differentiation in spinal cordGO:002151510.019
taxisGO:00423301570.019
Zebrafish Fly
hair follicle morphogenesisGO:003106920.019
cellular response to lipidGO:00713961270.019
negative regulation of intracellular signal transductionGO:19025321830.019
photoreceptor cell differentiationGO:004653020.019
positive regulation of secretion by cellGO:19035321080.019
chromatin modificationGO:00165682980.019
kidney developmentGO:0001822530.019
Mouse
protein modification by small protein conjugationGO:00324463420.019
digestive system developmentGO:0055123750.019
regulation of gtpase activityGO:00430871800.019
digestive tract developmentGO:0048565750.019
apoptotic signaling pathwayGO:00971902680.019
regulation of growthGO:00400081650.019
sequestering of metal ionGO:0051238240.019
positive regulation of gtpase activityGO:00435471660.019
negative regulation of cell cycleGO:00457861930.019
maintenance of locationGO:00512351120.019
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.019
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.019
reactive oxygen species metabolic processGO:0072593750.019
forebrain generation of neuronsGO:002187230.019
posttranscriptional regulation of gene expressionGO:00106082130.019
regulation of cell morphogenesisGO:00226041530.019
positive regulation of organelle organizationGO:00106381950.019
cellular response to organic cyclic compoundGO:00714071270.019
anterior posterior axis specification embryoGO:000859520.019
heart contractionGO:0060047620.019
peptidyl tyrosine modificationGO:00182121700.018
regulation of metal ion transportGO:00109591200.018
cellular potassium ion transportGO:0071804600.018
ossificationGO:00015031210.018
negative regulation of protein phosphorylationGO:00019331400.018
covalent chromatin modificationGO:00165692540.018
neuron developmentGO:00486661130.018
Zebrafish Fly
amide transportGO:0042886760.018
heart processGO:0003015620.018
sensory perceptionGO:00076001030.018
atp metabolic processGO:00460341760.018
negative regulation of locomotionGO:00400131180.018
mesonephric duct developmentGO:007217730.018
reproductive processGO:00224141060.018
syncytium formation by plasma membrane fusionGO:000076820.018
hormone secretionGO:0046879650.018
av node cell to bundle of his cell communicationGO:008606740.018
nucleoside monophosphate metabolic processGO:00091231910.018
regulation of intracellular protein transportGO:00331571230.018
anion transmembrane transportGO:0098656760.018
endodermal cell fate commitmentGO:000171140.018
regulation of ras protein signal transductionGO:00465781550.018
thymus developmentGO:004853830.018
negative regulation of testicular blood vessel morphogenesisGO:006136910.018
response to drugGO:0042493810.018
neural crest cell developmentGO:001403230.018
regulation of ion homeostasisGO:2000021730.017
inorganic anion transmembrane transportGO:0098661470.017
immune effector processGO:00022521590.017
reactive nitrogen species metabolic processGO:200105730.017
regulation of muscle contractionGO:0006937450.017
epithelial cell differentiationGO:00308551410.017
potassium ion transportGO:0006813620.017
small molecule biosynthetic processGO:00442831570.017
cell cycle phase transitionGO:00447701730.017
sensory organ developmentGO:0007423520.017
regulation of cytoskeleton organizationGO:00514931770.017
innate immune responseGO:00450871780.017
gtp metabolic processGO:00460392390.017
testosterone biosynthetic processGO:006137020.017
forebrain dorsal ventral pattern formationGO:002179810.017
tripartite regional subdivisionGO:000735120.017
protein localization to membraneGO:00726571600.017
negative regulation of transmission of nerve impulseGO:005197010.017
rhythmic behaviorGO:000762220.017
salivary gland morphogenesisGO:000743540.017
regulation of heart contractionGO:0008016500.017
positive regulation of transferase activityGO:00513472270.017
peptidyl tyrosine phosphorylationGO:00181081700.017
positive regulation of ras gtpase activityGO:00323201170.017
negative regulation of cell migrationGO:00303361020.017
somitogenesisGO:000175620.017
monocarboxylic acid metabolic processGO:00327871850.017
forebrain neuron differentiationGO:002187930.017
regulation of hormone secretionGO:0046883570.017
cell activationGO:00017752130.017
regulation of peptidyl tyrosine phosphorylationGO:00507301080.017
cell proliferation in forebrainGO:002184610.017
epithelium migrationGO:00901321190.017
soft palate developmentGO:006002330.017
canonical wnt signaling pathwayGO:00600701160.017
positive regulation of protein transportGO:00512221350.017
myoblast fusionGO:000752010.017
cellular protein catabolic processGO:00442572610.017
epithelial cell migrationGO:00106311190.017
cell part morphogenesisGO:00329901370.017
Zebrafish Fly
circadian behaviorGO:004851220.017
purine nucleoside monophosphate catabolic processGO:00091281580.016
epithelial cell proliferationGO:00506731280.016
organic hydroxy compound metabolic processGO:19016151470.016
receptor metabolic processGO:0043112810.016
protein processingGO:00164852260.016
regulation of peptidase activityGO:00525471800.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
endodermal cell fate specificationGO:000171440.016
dephosphorylationGO:00163112090.016
luteinizing hormone secretionGO:003227510.016
negative regulation of hydrolase activityGO:00513461820.016
urogenital system developmentGO:0001655650.016
Mouse
multicellular organismal signalingGO:0035637340.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.016
cell type specific apoptotic processGO:00972851250.016
ameboidal type cell migrationGO:00016671350.016
positive regulation of mapk cascadeGO:00434101900.016
oocyte developmentGO:004859910.016
hindlimb morphogenesisGO:003513720.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
morphogenesis of an epitheliumGO:0002009600.016
regulation of ras gtpase activityGO:00323181280.016
single organism reproductive processGO:0044702980.016
histone modificationGO:00165702510.016
pituitary gland developmentGO:002198320.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of bindingGO:00510981110.016
epidermis morphogenesisGO:004873030.016
regulation of transmission of nerve impulseGO:005196920.016
post embryonic organ developmentGO:004856910.016
interspecies interaction between organismsGO:00444191560.016
signal releaseGO:0023061700.016
embryonic camera type eye developmentGO:003107620.016
positive regulation of cell cycleGO:00457871400.016
organophosphate biosynthetic processGO:00904071630.016
plasma membrane organizationGO:00070091150.016
reactive oxygen species biosynthetic processGO:190340940.016
long term memoryGO:000761620.016
cell substrate adhesionGO:00315891320.016
regulation of striated muscle contractionGO:0006942370.016
sodium ion transportGO:0006814610.016
membrane hyperpolarizationGO:006008110.016
cardiac cell fate determinationGO:006091330.016
spermatid differentiationGO:004851540.016
regulation of multi organism processGO:00439001570.016
positive regulation of cytokine productionGO:00018191670.016
rna processingGO:00063962550.016
embryonic viscerocranium morphogenesisGO:004870310.015
viral processGO:00160321460.015

SIM1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.062
nervous system diseaseDOID:8634310.045
sensory system diseaseDOID:00501552030.045
eye diseaseDOID:56141490.035
eye and adnexa diseaseDOID:14921500.035
disease of metabolismDOID:00146672950.030
retinal diseaseDOID:56791180.028
cardiovascular system diseaseDOID:12871060.026
muscular diseaseDOID:00800001140.025
muscle tissue diseaseDOID:661130.025
cancerDOID:1621670.024
disease of cellular proliferationDOID:145661740.024
organ system cancerDOID:00506861640.021
central nervous system diseaseDOID:3311860.020
inherited metabolic disorderDOID:6552420.020
myopathyDOID:4231040.020
immune system diseaseDOID:29141550.019
bone diseaseDOID:0080001880.016
connective tissue diseaseDOID:651090.016