Homo sapiens

0 known processes

KDM1B

lysine (K)-specific demethylase 1B

(Aliases: FLJ33898,dJ298J15.2,C6orf193,DKFZp686I0412,AOF1,LSD2,bA204B7.3,FLJ34109,FLJ43328)

KDM1B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein maturationGO:00516042330.056
proteolysis involved in cellular protein catabolic processGO:00516032440.055
cellular protein catabolic processGO:00442572610.054
cellular amino acid metabolic processGO:00065201160.054
post embryonic developmentGO:000979120.054
negative regulation of protein metabolic processGO:00512483910.051
amine metabolic processGO:0009308440.048
cellular macromolecule catabolic processGO:00442653800.047
negative regulation of cellular protein metabolic processGO:00322693530.047
cellular amine metabolic processGO:0044106410.045
protein modification by small protein removalGO:0070646920.045
determination of adult lifespanGO:000834020.045
protein processingGO:00164852260.045
negative regulation of catalytic activityGO:00430863350.044
protein catabolic processGO:00301633250.043
regulation of peptidase activityGO:00525471800.042
regulation of cellular amino acid metabolic processGO:000652160.042
regulation of proteolysisGO:00301622930.042
regulation of cell cycleGO:00517263930.042
negative regulation of protein processingGO:00109551420.041
multicellular organismal agingGO:001025930.041
chromatin modificationGO:00165682980.041
Mouse
regulation of cellular ketone metabolic processGO:0010565500.040
cellular ketone metabolic processGO:0042180800.040
regulation of cellular amine metabolic processGO:0033238110.039
ras protein signal transductionGO:0007265730.039
regulation of protein processingGO:00706131500.037
small gtpase mediated signal transductionGO:0007264780.037
negative regulation of hydrolase activityGO:00513461820.036
cytoplasmic transportGO:00164823790.036
nucleoside triphosphate metabolic processGO:00091414220.035
ribonucleoside triphosphate metabolic processGO:00091994120.035
lipid metabolic processGO:00066293810.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
regulation of protein catabolic processGO:00421761550.033
purine ribonucleoside metabolic processGO:00461284370.033
nucleoside catabolic processGO:00091644080.033
female gamete generationGO:000729220.032
covalent chromatin modificationGO:00165692540.032
Mouse
cell growthGO:00160491600.032
protein deubiquitinationGO:0016579790.032
regulation of endopeptidase activityGO:00525481700.031
regulation of protein maturationGO:19033171500.031
ribonucleoside catabolic processGO:00424544060.031
nucleoside phosphate catabolic processGO:19012924120.031
cellular lipid metabolic processGO:00442553030.031
negative regulation of protein maturationGO:19033181420.030
single organism cellular localizationGO:19025803320.030
proteasomal protein catabolic processGO:00104981760.029
positive regulation of cellular amine metabolic processGO:003324070.029
cell morphogenesisGO:00009022960.029
purine containing compound catabolic processGO:00725234110.029
locomotory behaviorGO:000762610.028
organophosphate catabolic processGO:00464344300.028
nucleoside triphosphate catabolic processGO:00091433940.028
negative regulation of proteolysisGO:00458611320.028
chromatin organizationGO:00063253510.028
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
purine ribonucleotide catabolic processGO:00091544040.027
positive regulation of cellular component organizationGO:00511303760.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
ribonucleoside triphosphate catabolic processGO:00092033910.027
nucleotide catabolic processGO:00091664080.027
response to oxygen containing compoundGO:19017003690.027
ribonucleotide catabolic processGO:00092614050.026
transmembrane transportGO:00550853990.026
oogenesisGO:004847720.026
positive regulation of transportGO:00510503360.026
regulation of cell differentiationGO:00455953930.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
protein modification by small protein conjugationGO:00324463420.025
positive regulation of catabolic processGO:00098963100.025
purine nucleotide catabolic processGO:00061954050.024
purine nucleoside catabolic processGO:00061523980.024
vesicle mediated transportGO:00161923710.024
glycosyl compound catabolic processGO:19016584130.024
actin filament based processGO:00300292240.024
positive regulation of hydrolase activityGO:00513453310.023
neuromuscular junction developmentGO:000752830.023
purine ribonucleoside catabolic processGO:00461303980.023
negative regulation of phosphate metabolic processGO:00459362670.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
regulation of cell growthGO:00015581350.023
purine nucleoside triphosphate catabolic processGO:00091463920.023
segmentationGO:003528240.023
cellular response to dna damage stimulusGO:00069743790.023
negative regulation of peptidase activityGO:0010466910.022
regulation of anatomical structure morphogenesisGO:00226032860.022
regulation of cellular protein catabolic processGO:1903362960.022
positive regulation of cellular catabolic processGO:00313312840.022
defense responseGO:00069523150.022
immune responseGO:00069553070.022
regulation of proteasomal protein catabolic processGO:0061136870.022
ion transmembrane transportGO:00342203380.022
growthGO:00400072020.022
dephosphorylationGO:00163112090.022
single organism membrane organizationGO:00448022680.021
regulation of growthGO:00400081650.021
rho protein signal transductionGO:0007266260.021
cellular component morphogenesisGO:00329893140.021
response to abiotic stimulusGO:00096283360.021
protein ubiquitinationGO:00165673140.021
guanosine containing compound catabolic processGO:19010692390.021
metal ion transportGO:00300012720.021
cation transportGO:00068123310.021
cell projection organizationGO:00300302520.021
endosomal transportGO:00161971290.021
histone modificationGO:00165702510.020
Mouse
cell adhesionGO:00071553250.020
regulation of protein localizationGO:00328802960.020
membrane organizationGO:00610242920.020
biological adhesionGO:00226103310.020
negative regulation of endopeptidase activityGO:0010951840.020
gtp catabolic processGO:00061842370.020
regulation of cellular component biogenesisGO:00440872810.020
negative regulation of cellular component organizationGO:00511292350.020
system processGO:00030083490.020
mitotic cell cycleGO:00002783260.020
negative regulation of phosphorus metabolic processGO:00105632670.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.019
positive regulation of nucleotide metabolic processGO:00459812300.019
regulation of nucleotide metabolic processGO:00061402690.019
memoryGO:000761330.019
gtp metabolic processGO:00460392390.019
regulation of cell motilityGO:20001452990.019
regulation of cellular response to stressGO:00801352440.019
regulation of purine nucleotide metabolic processGO:19005422640.019
regulation of kinase activityGO:00435493140.019
regulation of cellular component movementGO:00512703340.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
signal transduction by phosphorylationGO:00230142970.018
negative regulation of apoptotic processGO:00430663160.018
carbohydrate derivative biosynthetic processGO:19011372070.018
cation transmembrane transportGO:00986552380.018
positive regulation of cell differentiationGO:00455972110.018
cell developmentGO:00484683280.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of intracellular transportGO:00323861950.018
apoptotic signaling pathwayGO:00971902680.018
regulation of establishment of protein localizationGO:00702012420.018
positive regulation of immune system processGO:00026842830.018
positive regulation of phosphorylationGO:00423273940.018
regulation of transferase activityGO:00513383550.018
blastoderm segmentationGO:000735020.018
negative regulation of protein modification processGO:00314002000.017
regulation of nucleoside metabolic processGO:00091182090.017
negative regulation of cellular amine metabolic processGO:003323930.017
ion homeostasisGO:00508012300.017
endomembrane system organizationGO:00102561960.017
guanosine containing compound metabolic processGO:19010682440.017
regulation of locomotionGO:00400123290.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
inorganic ion transmembrane transportGO:00986602310.017
oxidation reduction processGO:00551143960.017
chemical homeostasisGO:00488783060.017
monocarboxylic acid metabolic processGO:00327871850.017
interspecies interaction between organismsGO:00444191560.017
spermatid differentiationGO:004851540.017
lipid biosynthetic processGO:00086101770.017
regulation of purine nucleotide catabolic processGO:00331212050.017
regulation of nucleotide catabolic processGO:00308112050.017
cellular homeostasisGO:00197251960.017
positive regulation of gtp catabolic processGO:00331261660.016
nervous system developmentGO:00073992930.016
mitotic cell cycle processGO:19030472860.016
regulation of mapk cascadeGO:00434082620.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
oocyte developmentGO:004859910.016
regulation of cytoskeleton organizationGO:00514931770.016
morphogenesis of embryonic epitheliumGO:001633140.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
adult locomotory behaviorGO:000834410.016
regulation of protein kinase activityGO:00458592890.016
carbohydrate metabolic processGO:00059752070.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of gtpase activityGO:00430871800.016
response to other organismGO:00517072610.016
ubiquitin dependent protein catabolic processGO:00065112060.016
negative regulation of cell deathGO:00605483450.016
regulation of ras protein signal transductionGO:00465781550.016
regulation of cell migrationGO:00303342890.016
associative learningGO:000830610.016
positive regulation of nucleotide catabolic processGO:00308131850.016
regulation of cell morphogenesisGO:00226041530.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
cellular response to oxygen containing compoundGO:19017012760.016
compound eye developmentGO:004874910.016
anterior posterior axis specificationGO:000994820.016
nitrogen compound transportGO:00717051910.015
microtubule based processGO:00070172100.015
positive regulation of synaptic transmissionGO:005080640.015
cytokine productionGO:00018162470.015
positive regulation of developmental processGO:00510943140.015
positive regulation of nucleoside metabolic processGO:00459791860.015
peripheral nervous system developmentGO:000742220.015
cellular macromolecular complex assemblyGO:00346223240.015
positive regulation of cell deathGO:00109422630.015
negative regulation of multicellular organismal processGO:00512413170.015
regulation of protein complex assemblyGO:00432541470.015
intracellular protein transportGO:00068862700.015
regenerationGO:003109940.015
establishment of protein localization to organelleGO:00725941720.015
secretion by cellGO:00329402260.015
cellular response to endogenous stimulusGO:00714953360.015
cellular chemical homeostasisGO:00550821800.015
mapk cascadeGO:00001652880.015
spermatid developmentGO:000728640.015
modification dependent macromolecule catabolic processGO:00436322120.015
reactive oxygen species metabolic processGO:0072593750.015
positive regulation of gtpase activityGO:00435471660.015
cardiac muscle cell contractionGO:008600340.015
innate immune responseGO:00450871780.015
multi organism cellular processGO:00447641560.015
cellular protein complex assemblyGO:00436231880.015
regulation of protein transportGO:00512232130.015
inorganic cation transmembrane transportGO:00986621940.015
response to external biotic stimulusGO:00432072610.015
positive regulation of programmed cell deathGO:00430682490.015
regulation of gtp catabolic processGO:00331241800.015
regulation of cell cycle processGO:00105642660.014
regulation of cytokine productionGO:00018172320.014
protein localization to organelleGO:00333652800.014
reactive oxygen species biosynthetic processGO:190340940.014
negative regulation of developmental processGO:00510932470.014
positive regulation of protein phosphorylationGO:00019343130.014
regulation of cytoplasmic transportGO:19036491490.014
neuroblast proliferationGO:000740540.014
viral processGO:00160321460.014
organophosphate biosynthetic processGO:00904071630.014
negative regulation of transportGO:00510511760.014
regulation of response to external stimulusGO:00321012220.014
negative regulation of intracellular signal transductionGO:19025321830.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of secretionGO:00510461940.014
small molecule biosynthetic processGO:00442831570.014
secretionGO:00469032540.014
maintenance of locationGO:00512351120.014
hindbrain developmentGO:003090230.014
single organism carbohydrate metabolic processGO:00447231930.014
organelle assemblyGO:00709251760.014
nucleocytoplasmic transportGO:00069131760.014
negative regulation of cell proliferationGO:00082852280.014
positive regulation of apoptotic processGO:00430652460.013
reactive nitrogen species metabolic processGO:200105730.013
protein localization to membraneGO:00726571600.013
cell divisionGO:00513011680.013
nuclear transportGO:00511691790.013
regulation of secretion by cellGO:19035301770.013
histone deubiquitinationGO:0016578160.013
modification dependent protein catabolic processGO:00199412090.013
oocyte differentiationGO:000999420.013
positive regulation of organelle organizationGO:00106381950.013
negative regulation of phosphorylationGO:00423261740.013
rhythmic behaviorGO:000762220.013
rab protein signal transductionGO:003248240.013
negative regulation of cell cycleGO:00457861930.013
positive regulation of transferase activityGO:00513472270.013
embryonic epithelial tube formationGO:000183840.013
actin cytoskeleton organizationGO:00300362070.013
neurological system processGO:00508771630.013
rna processingGO:00063962550.013
positive regulation of ras gtpase activityGO:00323201170.013
response to biotic stimulusGO:00096072760.013
nerve developmentGO:002167540.013
metal ion homeostasisGO:00550651690.013
tripartite regional subdivisionGO:000735120.013
protein oligomerizationGO:00512591730.013
actin filament based movementGO:0030048170.013
microtubule cytoskeleton organizationGO:00002261760.012
cell part morphogenesisGO:00329901370.012
regulation of immune responseGO:00507762010.012
regulation of vesicle mediated transportGO:00606271300.012
cation homeostasisGO:00550801890.012
establishment of protein localization to membraneGO:00901501210.012
actin mediated cell contractionGO:0070252120.012
inner ear morphogenesisGO:004247240.012
positive regulation of kinase activityGO:00336742040.012
glycoprotein metabolic processGO:00091001100.012
neurotransmitter secretionGO:000726940.012
organic acid biosynthetic processGO:0016053970.012
anion transportGO:00068201610.012
limbic system developmentGO:002176130.012
regulation of multi organism processGO:00439001570.012
posttranscriptional regulation of gene expressionGO:00106082130.012
motor neuron axon guidanceGO:000804520.012
cellular cation homeostasisGO:00300031630.012
regulation of protein serine threonine kinase activityGO:00719001790.012
divalent metal ion transportGO:00708381520.012
cellular metal ion homeostasisGO:00068751460.012
circulatory system developmentGO:00723592620.012
regulation of synaptic plasticityGO:004816730.012
fatty acid metabolic processGO:00066311150.012
circadian behaviorGO:004851220.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
peptidyl lysine modificationGO:00182051440.012
positive regulation of cellular component biogenesisGO:00440891580.012
matingGO:000761810.012
response to axon injuryGO:004867810.012
regulation of apoptotic signaling pathwayGO:20012331750.012
response to fungusGO:000962040.012
single organism cell adhesionGO:00986021790.012
anterior posterior axis specification embryoGO:000859520.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
response to cytokineGO:00340972320.012
regulation of cell developmentGO:00602841610.012
protein acylationGO:00435431380.012
response to organic cyclic compoundGO:00140702040.012
protein targetingGO:00066051870.012
response to growth factorGO:00708482050.012
neural tube formationGO:000184130.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
cell projection assemblyGO:00300311260.011
calcium ion transportGO:00068161470.011
glycerolipid metabolic processGO:00464861070.011
response to nitrogen compoundGO:19016981840.011
neurogenesisGO:00220081690.011
divalent inorganic cation transportGO:00725111580.011
negative regulation of protein phosphorylationGO:00019331400.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
cellular ion homeostasisGO:00068731680.011
cell fate determinationGO:000170930.011
regulation of neural precursor cell proliferationGO:200017740.011
positive regulation of protein transportGO:00512221350.011
methylationGO:00322591060.011
Mouse
protein polyubiquitinationGO:00002091100.011
regulation of protein stabilityGO:0031647870.011
positive regulation of protein kinase activityGO:00458601900.011
organ formationGO:004864530.011
hemopoiesisGO:00300971800.011
endocytosisGO:00068971590.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
midgut developmentGO:000749410.011
sequestering of metal ionGO:0051238240.011
cell projection morphogenesisGO:00488581290.011
response to radiationGO:00093141510.011
positive regulation of proteolysisGO:00458621420.011
regulation of ras gtpase activityGO:00323181280.011
mitochondrion organizationGO:00070051560.011
positive regulation of cell proliferationGO:00082843010.011
photoreceptor cell differentiationGO:004653020.011
generation of neuronsGO:00486991520.011
salivary gland morphogenesisGO:000743540.011
rna interferenceGO:001624640.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
cellular response to cytokine stimulusGO:00713451810.011
visual behaviorGO:000763220.011
negative regulation of transferase activityGO:00513481240.011
organic hydroxy compound metabolic processGO:19016151470.011
syncytium formation by plasma membrane fusionGO:000076820.011
mitotic cell cycle phase transitionGO:00447721620.011
atp metabolic processGO:00460341760.011
negative regulation of organelle organizationGO:00106391260.011
regulation of actin filament based processGO:00329701410.011
monovalent inorganic cation transportGO:00156721280.011
immune effector processGO:00022521590.011
carboxylic acid biosynthetic processGO:0046394970.010
nucleus localizationGO:005164710.010
immune system developmentGO:00025201950.010
cell cell signalingGO:00072671550.010
protein autophosphorylationGO:00467771230.010
positive regulation of cytokine productionGO:00018191670.010
regulation of cell adhesionGO:00301551660.010
wnt signaling pathwayGO:00160551560.010
protein homooligomerizationGO:00512601000.010
organelle fissionGO:00482851490.010
metencephalon developmentGO:002203720.010
somitogenesisGO:000175620.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
ameboidal type cell migrationGO:00016671350.010
positive regulation of secretionGO:00510471160.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
meiosis iGO:000712740.010
regulation of ion transportGO:00432691890.010
cytokinesisGO:0000910960.010
myoblast fusionGO:000752010.010
central nervous system developmentGO:00074171230.010
positive regulation of immune responseGO:00507781590.010
macromolecule methylationGO:0043414970.010
Mouse
monoubiquitinated protein deubiquitinationGO:003552060.010
neuron differentiationGO:00301821380.010
cardiovascular system developmentGO:00723582620.010
cell substrate adhesionGO:00315891320.010
sensory perception of smellGO:000760820.010
sensory perception of painGO:001923340.010
protein dephosphorylationGO:0006470810.010
cell cycle phase transitionGO:00447701730.010
epithelium developmentGO:00604292270.010
regulation of defense responseGO:00313471540.010
nucleoside monophosphate metabolic processGO:00091231910.010
engulfment of apoptotic cellGO:004365220.010

KDM1B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.033
musculoskeletal system diseaseDOID:172230.023
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
inherited metabolic disorderDOID:6552420.021
disease of cellular proliferationDOID:145661740.019
cancerDOID:1621670.019
sensory system diseaseDOID:00501552030.018
organ system cancerDOID:00506861640.017
neurodegenerative diseaseDOID:12891020.015
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
immune system diseaseDOID:29141550.013
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
myopathyDOID:4231040.012
retinal diseaseDOID:56791180.012
brain diseaseDOID:936730.012
connective tissue diseaseDOID:651090.011
cardiovascular system diseaseDOID:12871060.010