Homo sapiens

4 known processes

EDAR

ectodysplasin A receptor

(Aliases: DL,EDA1R,ED1R,FLJ94390,EDA3,HRM1,ED3,ED5,EDA-A1R)

EDAR biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelium developmentGO:00604292270.144
cellular response to endogenous stimulusGO:00714953360.128
skin developmentGO:0043588760.123
anatomical structure formation involved in morphogenesisGO:00486462840.119
organ morphogenesisGO:00098871470.114
cell adhesionGO:00071553250.109
regulation of sequence specific dna binding transcription factor activityGO:00510902110.106
salivary gland morphogenesisGO:000743540.104
odontogenesisGO:0042476250.101
cell substrate adhesionGO:00315891320.096
biological adhesionGO:00226103310.095
positive regulation of transportGO:00510503360.094
wnt signaling pathwayGO:00160551560.090
canonical wnt signaling pathwayGO:00600701160.088
hair cycleGO:0042633280.087
regulation of cellular ketone metabolic processGO:0010565500.085
negative regulation of programmed cell deathGO:00430693210.083
regulation of establishment of protein localizationGO:00702012420.070
regulation of locomotionGO:00400123290.067
regulation of canonical wnt signaling pathwayGO:0060828880.066
regulation of cellular amino acid metabolic processGO:000652160.066
post embryonic developmentGO:000979120.062
hair follicle morphogenesisGO:003106920.062
intracellular protein transportGO:00068862700.061
epidermis developmentGO:0008544590.060
regulation of cellular component movementGO:00512703340.059
regulation of cell cycleGO:00517263930.059
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.059
tube morphogenesisGO:0035239950.058
cytoplasmic transportGO:00164823790.058
single organism cellular localizationGO:19025803320.058
positive regulation of cellular amine metabolic processGO:003324070.058
regulation of wnt signaling pathwayGO:00301111230.057
positive regulation of wnt signaling pathwayGO:0030177540.057
small gtpase mediated signal transductionGO:0007264780.057
negative regulation of developmental processGO:00510932470.056
negative regulation of cell deathGO:00605483450.055
regulation of i kappab kinase nf kappab signalingGO:00431221620.055
negative regulation of apoptotic processGO:00430663160.054
tube developmentGO:00352951250.053
epidermis morphogenesisGO:004873030.052
ectodermal placode formationGO:006078810.051
regulation of cell differentiationGO:00455953930.050
regulation of cell migrationGO:00303342890.050
ectodermal placode developmentGO:007169610.049
positive regulation of cellular amino acid metabolic processGO:004576430.047
cellular amino acid metabolic processGO:00065201160.046
protein processingGO:00164852260.045
cellular ketone metabolic processGO:0042180800.044
positive regulation of cellular component organizationGO:00511303760.044
immune responseGO:00069553070.043
negative regulation of catalytic activityGO:00430863350.043
cellular amine metabolic processGO:0044106410.042
epithelial cell differentiationGO:00308551410.042
response to organic cyclic compoundGO:00140702040.041
tissue migrationGO:00901301190.040
negative regulation of multicellular organismal processGO:00512413170.040
negative regulation of protein metabolic processGO:00512483910.040
regulation of cellular amine metabolic processGO:0033238110.040
regulation of cytoplasmic transportGO:19036491490.040
i kappab kinase nf kappab signalingGO:00072491660.040
regulation of protein localizationGO:00328802960.040
negative regulation of cell proliferationGO:00082852280.039
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.039
cytokine productionGO:00018162470.037
regulation of protein transportGO:00512232130.037
nucleocytoplasmic transportGO:00069131760.037
negative regulation of cellular protein metabolic processGO:00322693530.037
amine metabolic processGO:0009308440.036
positive regulation of cell differentiationGO:00455972110.036
positive regulation of programmed cell deathGO:00430682490.036
circulatory system developmentGO:00723592620.036
vasculature developmentGO:00019441810.035
regulation of intracellular protein transportGO:00331571230.035
defense responseGO:00069523150.035
nuclear transportGO:00511691790.034
positive regulation of canonical wnt signaling pathwayGO:0090263330.033
regulation of cellular response to stressGO:00801352440.033
protein importGO:00170381300.033
chemical homeostasisGO:00488783060.033
protein targetingGO:00066051870.033
regulation of intracellular transportGO:00323861950.033
protein maturationGO:00516042330.033
ras protein signal transductionGO:0007265730.033
blood vessel morphogenesisGO:00485141620.033
protein import into nucleusGO:00066061040.033
gland developmentGO:0048732480.032
response to lipidGO:00339932060.032
regulation of nucleocytoplasmic transportGO:0046822980.032
positive regulation of immune system processGO:00026842830.031
regulation of cell motilityGO:20001452990.031
actin filament based processGO:00300292240.031
positive regulation of hydrolase activityGO:00513453310.031
stem cell differentiationGO:0048863930.031
organ formationGO:004864530.031
positive regulation of phosphorylationGO:00423273940.029
positive regulation of cell cycleGO:00457871400.029
cell morphogenesisGO:00009022960.029
positive regulation of aldosterone metabolic processGO:003234620.029
regulation of protein targetingGO:1903533910.029
positive regulation of protein phosphorylationGO:00019343130.028
determination of adult lifespanGO:000834020.028
regulation of anatomical structure morphogenesisGO:00226032860.028
positive regulation of intracellular protein transportGO:0090316760.028
multicellular organismal agingGO:001025930.028
regulation of body fluid levelsGO:0050878990.028
regulation of peptidase activityGO:00525471800.028
response to abiotic stimulusGO:00096283360.027
regulation of cell cycle processGO:00105642660.027
positive regulation of developmental processGO:00510943140.027
positive regulation of cell deathGO:00109422630.027
positive regulation of cytoplasmic transportGO:1903651820.027
cellular response to dna damage stimulusGO:00069743790.026
system processGO:00030083490.026
regulation of transferase activityGO:00513383550.026
positive regulation of protein transportGO:00512221350.026
keratinizationGO:003142420.026
response to other organismGO:00517072610.026
negative regulation of cell differentiationGO:00455961710.025
small molecule biosynthetic processGO:00442831570.025
purine ribonucleoside metabolic processGO:00461284370.025
cell growthGO:00160491600.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
purine nucleotide catabolic processGO:00061954050.025
protein targeting to nucleusGO:00447441040.025
purine containing compound catabolic processGO:00725234110.025
positive regulation of nf kappab transcription factor activityGO:0051092810.025
cardiovascular system developmentGO:00723582620.025
protein localization to nucleusGO:00345041360.024
nucleoside triphosphate metabolic processGO:00091414220.024
gtp metabolic processGO:00460392390.024
ectodermal placode morphogenesisGO:007169710.024
positive regulation of mapk cascadeGO:00434101900.024
female gamete generationGO:000729220.024
regulation of purine nucleotide metabolic processGO:19005422640.024
single organism nuclear importGO:19025931040.024
ion transmembrane transportGO:00342203380.024
cellular response to organic cyclic compoundGO:00714071270.024
organophosphate catabolic processGO:00464344300.024
thymus developmentGO:004853830.024
single organismal cell cell adhesionGO:00163371480.024
reactive nitrogen species metabolic processGO:200105730.024
signal transduction by phosphorylationGO:00230142970.023
inorganic ion transmembrane transportGO:00986602310.023
positive regulation of nucleotide metabolic processGO:00459812300.023
positive regulation of apoptotic processGO:00430652460.023
response to hormoneGO:00097251750.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of endopeptidase activityGO:00525481700.023
cellular macromolecule catabolic processGO:00442653800.023
regulation of protein import into nucleusGO:0042306780.023
regulation of mapk cascadeGO:00434082620.023
response to cytokineGO:00340972320.023
cell projection organizationGO:00300302520.023
epithelial cell proliferationGO:00506731280.023
sensory perceptionGO:00076001030.023
nucleoside catabolic processGO:00091644080.023
nuclear importGO:00511701060.023
hematopoietic or lymphoid organ developmentGO:00485341860.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
regulation of kinase activityGO:00435493140.022
positive regulation of intracellular transportGO:00323881040.022
regulation of cytoskeleton organizationGO:00514931770.022
single organism membrane organizationGO:00448022680.022
nucleoside triphosphate catabolic processGO:00091433940.022
regulation of protein processingGO:00706131500.022
odontogenesis of dentin containing toothGO:0042475100.021
positive regulation of nucleocytoplasmic transportGO:0046824540.021
cardiac muscle cell contractionGO:008600340.021
hemopoiesisGO:00300971800.021
cellular cation homeostasisGO:00300031630.021
oogenesisGO:004847720.021
purine nucleoside catabolic processGO:00061523980.021
gtp catabolic processGO:00061842370.021
positive regulation of cellular component movementGO:00512721810.021
growthGO:00400072020.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
apoptotic signaling pathwayGO:00971902680.021
plasma membrane organizationGO:00070091150.021
metal ion transportGO:00300012720.021
response to external biotic stimulusGO:00432072610.020
regulation of protein localization to nucleusGO:1900180850.020
membrane organizationGO:00610242920.020
negative regulation of locomotionGO:00400131180.020
protein oligomerizationGO:00512591730.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
regulation of vasculature developmentGO:1901342970.020
reactive oxygen species biosynthetic processGO:190340940.020
positive regulation of cellular catabolic processGO:00313312840.020
protein localization to membraneGO:00726571600.020
chromatin organizationGO:00063253510.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
epithelium migrationGO:00901321190.019
regulation of cell growthGO:00015581350.019
cellular response to cytokine stimulusGO:00713451810.019
response to biotic stimulusGO:00096072760.019
positive regulation of steroid hormone biosynthetic processGO:009003120.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
organic hydroxy compound metabolic processGO:19016151470.019
anatomical structure homeostasisGO:00602491000.019
positive regulation of catabolic processGO:00098963100.019
hair cycle processGO:0022405120.019
regulation of protein kinase activityGO:00458592890.019
protein localization to organelleGO:00333652800.019
negative regulation of cellular component movementGO:00512711060.019
immune effector processGO:00022521590.019
regulation of nucleotide catabolic processGO:00308112050.019
actin cytoskeleton organizationGO:00300362070.019
regulation of cellular component biogenesisGO:00440872810.019
epithelial cell migrationGO:00106311190.019
regulation of protein maturationGO:19033171500.019
ameboidal type cell migrationGO:00016671350.019
establishment of protein localization to membraneGO:00901501210.019
negative regulation of cellular component organizationGO:00511292350.019
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of ion transportGO:00432691890.019
single organism cell adhesionGO:00986021790.019
lipid metabolic processGO:00066293810.019
response to woundingGO:00096111680.018
regulation of proteolysisGO:00301622930.018
positive regulation of acrosome reactionGO:200034440.018
regulation of purine nucleotide catabolic processGO:00331212050.018
regulation of nucleotide metabolic processGO:00061402690.018
regulation of nucleoside metabolic processGO:00091182090.018
positive regulation of protein import into nucleusGO:0042307460.018
posttranscriptional regulation of gene expressionGO:00106082130.018
purine ribonucleotide catabolic processGO:00091544040.018
regulation of cell developmentGO:00602841610.018
positive regulation of cell cycle processGO:00900681060.018
rho protein signal transductionGO:0007266260.018
cellular ion homeostasisGO:00068731680.018
positive regulation of transferase activityGO:00513472270.017
positive regulation of kinase activityGO:00336742040.017
cell divisionGO:00513011680.017
positive regulation of organelle organizationGO:00106381950.017
chromatin modificationGO:00165682980.017
protein catabolic processGO:00301633250.017
negative regulation of intracellular signal transductionGO:19025321830.017
negative regulation of cell migrationGO:00303361020.017
endomembrane system organizationGO:00102561960.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
trachea developmentGO:006043810.017
cation transmembrane transportGO:00986552380.017
cellular component morphogenesisGO:00329893140.017
nucleoside phosphate catabolic processGO:19012924120.017
cellular response to oxygen containing compoundGO:19017012760.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
regulation of mitotic cell cycleGO:00073461890.017
immune system developmentGO:00025201950.017
glycosyl compound catabolic processGO:19016584130.017
neurological system processGO:00508771630.017
mapk cascadeGO:00001652880.016
cellular response to growth factor stimulusGO:00713631970.016
spermatid differentiationGO:004851540.016
protein localization to plasma membraneGO:0072659930.016
angiogenesisGO:00015251470.016
negative regulation of protein modification processGO:00314002000.016
skeletal system developmentGO:0001501790.016
negative regulation of cell motilityGO:20001461040.016
alcohol metabolic processGO:00060661140.016
cell activationGO:00017752130.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
guanosine containing compound catabolic processGO:19010692390.016
sulfur compound metabolic processGO:00067901010.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
reactive oxygen species metabolic processGO:0072593750.016
keratinocyte differentiationGO:0030216360.015
regulation of response to external stimulusGO:00321012220.015
regenerationGO:003109940.015
carbohydrate metabolic processGO:00059752070.015
ribonucleoside catabolic processGO:00424544060.015
covalent chromatin modificationGO:00165692540.015
mitotic cell cycle processGO:19030472860.015
negative regulation of vasculature developmentGO:1901343430.015
positive regulation of cell motilityGO:20001471770.015
cannabinoid signaling pathwayGO:003817120.015
morphogenesis of embryonic epitheliumGO:001633140.015
molting cycleGO:0042303280.015
organic hydroxy compound biosynthetic processGO:1901617710.015
purine ribonucleoside catabolic processGO:00461303980.015
epidermal cell differentiationGO:0009913450.015
negative regulation of phosphorylationGO:00423261740.015
response to oxygen containing compoundGO:19017003690.015
regulation of ras protein signal transductionGO:00465781550.015
segmentationGO:003528240.015
regulation of cytokine productionGO:00018172320.015
positive regulation of cell migrationGO:00303351720.015
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433620.015
non canonical wnt signaling pathway via mapk cascadeGO:003803040.015
inorganic cation transmembrane transportGO:00986621940.015
nucleotide catabolic processGO:00091664080.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
response to oxygen levelsGO:00704821000.015
oxidation reduction processGO:00551143960.015
stress activated mapk cascadeGO:0051403930.015
morphogenesis of an epitheliumGO:0002009600.015
positive regulation of nucleoside metabolic processGO:00459791860.014
negative regulation of phosphate metabolic processGO:00459362670.014
peripheral nervous system developmentGO:000742220.014
neuromuscular junction developmentGO:000752830.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
matingGO:000761810.014
establishment of protein localization to organelleGO:00725941720.014
vesicle mediated transportGO:00161923710.014
response to inorganic substanceGO:00100351270.014
cellular response to lipidGO:00713961270.014
response to growth factorGO:00708482050.014
response to steroid hormoneGO:0048545800.014
cranial nerve developmentGO:002154540.014
spermatid developmentGO:000728640.014
head developmentGO:00603221080.014
myeloid cell differentiationGO:00300991170.014
positive regulation of cell proliferationGO:00082843010.014
histone modificationGO:00165702510.014
stem cell developmentGO:0048864690.014
negative regulation of cell cycleGO:00457861930.014
regulation of actin filament based processGO:00329701410.014
negative regulation of protein maturationGO:19033181420.014
steroid metabolic processGO:0008202940.014
cellular protein catabolic processGO:00442572610.014
basement membrane organizationGO:007171130.013
sex determinationGO:000753030.013
ossificationGO:00015031210.013
embryonic camera type eye developmentGO:003107620.013
negative regulation of hydrolase activityGO:00513461820.013
negative regulation of proteolysisGO:00458611320.013
positive regulation of protein localization to nucleusGO:1900182480.013
blastoderm segmentationGO:000735020.013
oocyte developmentGO:004859910.013
muscle cell fate commitmentGO:004269340.013
regulation of epithelial cell proliferationGO:00506781130.013
dephosphorylationGO:00163112090.013
circulatory system processGO:00030131130.013
regulation of odontogenesisGO:004248140.013
peptide transportGO:0015833740.013
positive regulation of gtp catabolic processGO:00331261660.013
ribonucleotide catabolic processGO:00092614050.013
positive regulation of protein kinase activityGO:00458601900.013
regulation of multi organism processGO:00439001570.013
regulation of cell morphogenesisGO:00226041530.013
innate immune responseGO:00450871780.013
ion homeostasisGO:00508012300.013
positive regulation of cellular component biogenesisGO:00440891580.013
enzyme linked receptor protein signaling pathwayGO:00071673030.013
carbohydrate derivative biosynthetic processGO:19011372070.013
mitotic cell cycleGO:00002783260.013
cellular homeostasisGO:00197251960.013
anterior posterior axis specificationGO:000994820.013
activation of immune responseGO:00022531140.013
embryonic forelimb morphogenesisGO:003511540.013
positive regulation of gtpase activityGO:00435471660.013
negative regulation of endopeptidase activityGO:0010951840.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
negative regulation of protein processingGO:00109551420.013
protein acylationGO:00435431380.013
tissue homeostasisGO:0001894630.013
regulation of gtpase activityGO:00430871800.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
regulation of gtp catabolic processGO:00331241800.013
connective tissue developmentGO:0061448390.013
regulation of apoptotic signaling pathwayGO:20012331750.013
memoryGO:000761330.013
nerve developmentGO:002167540.013
chemotaxisGO:00069351570.013
jnk cascadeGO:0007254800.013
osteoblast differentiationGO:0001649920.013
t cell differentiation in thymusGO:003307740.013
positive regulation of cell developmentGO:0010720920.013
multicellular organismal homeostasisGO:0048871670.012
divalent inorganic cation homeostasisGO:00725071360.012
regulation of dna metabolic processGO:00510521530.012
cellular calcium ion homeostasisGO:00068741170.012
specification of organ identityGO:001009230.012
wound healingGO:00420601150.012
negative regulation of transportGO:00510511760.012
melanin metabolic processGO:000658210.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of cell divisionGO:0051781590.012
actin filament based movementGO:0030048170.012
tissue regenerationGO:004224630.012
cellular response to nitrogen compoundGO:19016991440.012
hindbrain developmentGO:003090230.012
negative regulation of cell adhesionGO:0007162640.012
defense response to other organismGO:00985421290.012
organelle assemblyGO:00709251760.012
hair follicle developmentGO:0001942110.012
response to decreased oxygen levelsGO:0036293960.012
axis elongationGO:000340140.012
rhythmic behaviorGO:000762220.012
negative regulation of protein phosphorylationGO:00019331400.012
viral processGO:00160321460.012
regulation of transcription factor import into nucleusGO:0042990390.012
nitrogen compound transportGO:00717051910.012
inflammatory responseGO:0006954790.012
regulation of angiogenesisGO:0045765920.012
leukocyte activationGO:00453211640.012
molting cycle processGO:0022404120.012
reproductive processGO:00224141060.012
negative regulation of peptidase activityGO:0010466910.012
regulation of stem cell differentiationGO:2000736560.012
positive regulation of aldosterone biosynthetic processGO:003234920.012
blood vessel developmentGO:00015681720.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of protein stabilityGO:0031647870.012
response to metal ionGO:0010038840.012
lung alveolus developmentGO:004828640.012
regulation of cell divisionGO:00513021160.012
sensory perception of smellGO:000760820.012
neuroblast proliferationGO:000740540.012
negative regulation of transferase activityGO:00513481240.012
regulation of acrosome reactionGO:006004640.012
regulation of protein serine threonine kinase activityGO:00719001790.012
inner ear morphogenesisGO:004247240.012
cell part morphogenesisGO:00329901370.012
cellular component disassemblyGO:0022411920.012
limbic system developmentGO:002176130.011
regulation of immune responseGO:00507762010.011
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.011
nervous system developmentGO:00073992930.011
amide transportGO:0042886760.011
negative regulation of immune system processGO:00026831360.011
microtubule based processGO:00070172100.011
taxisGO:00423301570.011
regulation of ras gtpase activityGO:00323181280.011
actin mediated cell contractionGO:0070252120.011
protein ubiquitinationGO:00165673140.011
cellular response to hormone stimulusGO:00328701250.011
cell projection assemblyGO:00300311260.011
cell type specific apoptotic processGO:00972851250.011
glycoprotein metabolic processGO:00091001100.011
guanosine containing compound metabolic processGO:19010682440.011
central nervous system developmentGO:00074171230.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
transcription factor import into nucleusGO:0042991400.011
secretion by cellGO:00329402260.011
cell cycle phase transitionGO:00447701730.011
g protein coupled receptor signaling pathwayGO:00071862070.011
negative regulation of wnt signaling pathwayGO:0030178690.011
positive regulation of keratinocyte proliferationGO:001083840.011
cellular macromolecular complex assemblyGO:00346223240.011
response to axon injuryGO:004867810.011
negative regulation of cell cycle processGO:00109481210.011
monocarboxylic acid metabolic processGO:00327871850.011
regulation of response to woundingGO:19030341010.011
cell aggregationGO:009874310.011
endocrine processGO:0050886250.011
negative regulation of glucocorticoid biosynthetic processGO:003194740.011
negative regulation of growthGO:0045926970.011
stress activated protein kinase signaling cascadeGO:0031098940.011
regulation of lymphocyte activationGO:00512491030.011
regulation of secretionGO:00510461940.011
peptidyl lysine acetylationGO:00183941010.011
oocyte differentiationGO:000999420.011
peptidyl lysine modificationGO:00182051440.011
negative regulation of angiogenesisGO:0016525390.011
cell developmentGO:00484683280.011
prostate gland developmentGO:003085030.011
response to hypoxiaGO:0001666960.011
modification dependent protein catabolic processGO:00199412090.011
developmental programmed cell deathGO:001062330.011
single organism carbohydrate metabolic processGO:00447231930.011
intracellular receptor signaling pathwayGO:00305221040.011
stem cell divisionGO:001714520.010
regulation of stress activated protein kinase signaling cascadeGO:0070302850.010
regulation of defense responseGO:00313471540.010
forelimb morphogenesisGO:003513640.010
establishment of protein localization to plasma membraneGO:0090002680.010
response to estrogenGO:0043627470.010
positive regulation of transcription factor import into nucleusGO:0042993250.010
multi organism cellular processGO:00447641560.010
dna repairGO:00062811980.010

EDAR disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system diseaseDOID:77360.360
mouth diseaseDOID:403140.360
tooth diseaseDOID:1091140.360
nervous system diseaseDOID:8634310.043
sensory system diseaseDOID:00501552030.043
eye and adnexa diseaseDOID:14921500.025
eye diseaseDOID:56141490.018
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
tooth agenesisDOID:005059150.013
disease of metabolismDOID:00146672950.012
kidney diseaseDOID:557360.012
urinary system diseaseDOID:18400.012
renal tubular transport diseaseDOID:447110.012
auditory system diseaseDOID:2742530.012
immune system diseaseDOID:29141550.012
connective tissue diseaseDOID:651090.012
musculoskeletal system diseaseDOID:172230.012
inherited metabolic disorderDOID:6552420.011