Homo sapiens

113 known processes

CDK5

cyclin-dependent kinase 5

(Aliases: PSSALRE)

CDK5 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of axon extensionGO:003051720.685
Mouse
positive regulation of protein targeting to membraneGO:009031480.614
Mouse
biological adhesionGO:00226103310.566
Mouse
negative regulation of axonogenesisGO:005077140.541
Mouse
post embryonic developmentGO:000979120.539
neuron cell cell adhesionGO:000715810.482
cell developmentGO:00484683280.395
Zebrafish Mouse Rat Fly
regulation of cell growthGO:00015581350.364
Mouse
regulation of cell cycle arrestGO:0071156360.268
cerebral cortex radially oriented cell migrationGO:002179910.242
Mouse
peptidyl serine modificationGO:00182091060.235
neuron differentiationGO:00301821380.232
Zebrafish Mouse Rat Fly
negative regulation of multicellular organismal processGO:00512413170.199
Mouse
negative regulation of cell growthGO:0030308830.181
Mouse
positive regulation of cellular component organizationGO:00511303760.180
Mouse
limbic system developmentGO:002176130.175
Mouse
intracellular protein transportGO:00068862700.174
Mouse
cell projection organizationGO:00300302520.167
Mouse Rat Fly
positive regulation of protein phosphorylationGO:00019343130.161
Mouse
negative regulation of apoptotic processGO:00430663160.157
Zebrafish
peptidyl threonine modificationGO:0018210450.153
Mouse
regulation of cell projection organizationGO:00313441070.153
Mouse
negative regulation of cellular component organizationGO:00511292350.151
Mouse
positive regulation of protein transportGO:00512221350.148
Mouse
dephosphorylationGO:00163112090.145
positive regulation of organelle organizationGO:00106381950.143
regulation of cell developmentGO:00602841610.139
Mouse
cerebral cortex cell migrationGO:002179530.135
Mouse
hemostasisGO:0007599760.135
generation of neuronsGO:00486991520.129
Zebrafish Mouse Rat Fly
growthGO:00400072020.127
Mouse Fly
protein localization to membraneGO:00726571600.126
Mouse
single organism cell adhesionGO:00986021790.124
small gtpase mediated signal transductionGO:0007264780.122
embryonic retina morphogenesis in camera type eyeGO:006005910.113
Zebrafish
tissue morphogenesisGO:0048729960.113
Zebrafish
cell cycle arrestGO:0007050710.109
cell growthGO:00160491600.104
Mouse
peptidyl serine phosphorylationGO:00181051010.102
regulation of protein transportGO:00512232130.101
Mouse
negative regulation of growthGO:0045926970.098
Mouse
amine metabolic processGO:0009308440.097
regulation of cellular amine metabolic processGO:0033238110.096
regulation of actin cytoskeleton organizationGO:00329561160.089
negative regulation of catalytic activityGO:00430863350.088
neurogenesisGO:00220081690.088
positive regulation of hydrolase activityGO:00513453310.087
single organismal cell cell adhesionGO:00163371480.087
serine phosphorylation of stat proteinGO:004250140.086
Mouse
reactive oxygen species metabolic processGO:0072593750.085
regulation of cellular amino acid metabolic processGO:000652160.085
regulation of proteolysisGO:00301622930.085
hippocampus developmentGO:002176610.082
Mouse
cellular response to dna damage stimulusGO:00069743790.082
negative regulation of phosphatase activityGO:0010923610.081
hindbrain developmentGO:003090230.081
Mouse
positive regulation of transportGO:00510503360.077
Mouse
single organism membrane organizationGO:00448022680.077
Mouse
positive regulation of transferase activityGO:00513472270.077
Mouse
positive regulation of protein kinase activityGO:00458601900.075
Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.075
small molecule biosynthetic processGO:00442831570.075
atp metabolic processGO:00460341760.074
cellular response to cytokine stimulusGO:00713451810.074
cell divisionGO:00513011680.074
negative regulation of neuron differentiationGO:0045665210.073
Mouse
cellular amine metabolic processGO:0044106410.071
negative regulation of cell cycleGO:00457861930.070
Mouse
cerebellum developmentGO:002154920.068
Mouse
sulfur compound metabolic processGO:00067901010.067
retina layer formationGO:001084230.066
Zebrafish
positive regulation of cellular amino acid metabolic processGO:004576430.065
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.064
cell projection morphogenesisGO:00488581290.064
Mouse Rat Fly
purine nucleoside triphosphate catabolic processGO:00091463920.064
regulation of protein localizationGO:00328802960.064
Mouse Worm
establishment of protein localization to membraneGO:00901501210.063
Mouse
regulation of cellular component sizeGO:0032535820.063
Mouse
cell morphogenesisGO:00009022960.063
Mouse Rat Fly
positive regulation of peptidase activityGO:0010952880.062
regulation of growthGO:00400081650.062
Mouse Fly
regulation of intracellular protein transportGO:00331571230.061
Mouse
cell adhesionGO:00071553250.060
Mouse
regulation of neuron projection developmentGO:0010975570.060
Mouse
negative regulation of programmed cell deathGO:00430693210.060
Zebrafish
lipid biosynthetic processGO:00086101770.060
dendritic spine morphogenesisGO:006099730.060
Mouse
regulation of protein serine threonine kinase activityGO:00719001790.060
purine ribonucleoside triphosphate metabolic processGO:00092054110.060
carbohydrate metabolic processGO:00059752070.059
chemotaxisGO:00069351570.059
Mouse Fly
jak stat cascadeGO:0007259460.059
microtubule based processGO:00070172100.058
cation transportGO:00068123310.057
Mouse
regulation of cell cycle processGO:00105642660.056
positive regulation of kinase activityGO:00336742040.055
Mouse
actin filament based processGO:00300292240.055
Rat
embryo developmentGO:00097901230.053
Zebrafish Worm
fatty acid metabolic processGO:00066311150.053
regulation of cell cycleGO:00517263930.053
Zebrafish Mouse Rat Fly
cellular response to oxygen containing compoundGO:19017012760.053
cellular ketone metabolic processGO:0042180800.052
purine containing compound catabolic processGO:00725234110.052
microtubule cytoskeleton organizationGO:00002261760.051
protein targetingGO:00066051870.050
Mouse
oogenesisGO:004847720.049
embryonic morphogenesisGO:0048598850.049
Zebrafish
negative regulation of developmental processGO:00510932470.048
Mouse
negative regulation of cell developmentGO:0010721480.048
Mouse
nervous system developmentGO:00073992930.048
negative regulation of cell deathGO:00605483450.047
cellular amino acid metabolic processGO:00065201160.047
ribonucleoside monophosphate catabolic processGO:00091581580.047
positive regulation of phosphorylationGO:00423273940.045
Mouse
regulation of cell differentiationGO:00455953930.045
Mouse
regulation of microtubule based processGO:0032886740.044
regulation of neurogenesisGO:0050767820.044
Mouse
regulation of cysteine type endopeptidase activityGO:20001161270.044
positive regulation of nucleoside metabolic processGO:00459791860.043
protein polymerizationGO:0051258710.043
regulation of microtubule cytoskeleton organizationGO:0070507610.042
positive regulation of intracellular protein transportGO:0090316760.042
Mouse
regulation of peptidase activityGO:00525471800.042
positive regulation of endopeptidase activityGO:0010950840.041
regulation of generation of precursor metabolites and energyGO:0043467270.040
regulation of cell morphogenesis involved in differentiationGO:0010769830.039
Mouse
regulation of cellular component biogenesisGO:00440872810.039
Fly
cellular cation homeostasisGO:00300031630.039
single organism cellular localizationGO:19025803320.039
Mouse
cell part morphogenesisGO:00329901370.039
Mouse Rat Fly
protein localization to organelleGO:00333652800.038
purine ribonucleoside metabolic processGO:00461284370.038
negative regulation of phosphorus metabolic processGO:00105632670.038
vesicle mediated transportGO:00161923710.038
Mouse Rat Worm
purine ribonucleoside catabolic processGO:00461303980.037
cellular chemical homeostasisGO:00550821800.037
nucleotide catabolic processGO:00091664080.037
ribonucleoside catabolic processGO:00424544060.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
regulation of cytoskeleton organizationGO:00514931770.036
enteroendocrine cell differentiationGO:003588360.036
glycosyl compound catabolic processGO:19016584130.035
protein glycosylationGO:0006486620.035
ion homeostasisGO:00508012300.035
positive regulation of cellular amine metabolic processGO:003324070.034
transmembrane transportGO:00550853990.034
peripheral nervous system developmentGO:000742220.034
Zebrafish Mouse
regulation of protein complex assemblyGO:00432541470.033
cellular component morphogenesisGO:00329893140.033
Mouse Rat Fly
actin cytoskeleton organizationGO:00300362070.033
Rat
regulation of cellular ketone metabolic processGO:0010565500.033
telencephalon cell migrationGO:002202940.033
Mouse
sensory organ developmentGO:0007423520.033
Zebrafish
regulation of anatomical structure sizeGO:00900661010.033
Mouse
cellular lipid metabolic processGO:00442553030.032
cation homeostasisGO:00550801890.032
carboxylic acid biosynthetic processGO:0046394970.032
regulation of protein targetingGO:1903533910.031
Mouse
eye developmentGO:0001654420.031
Zebrafish
blood coagulationGO:0007596760.031
cell activationGO:00017752130.031
ribonucleoside triphosphate metabolic processGO:00091994120.030
negative regulation of protein modification processGO:00314002000.030
Mouse
purine nucleoside monophosphate metabolic processGO:00091261860.030
nucleoside monophosphate metabolic processGO:00091231910.030
type b pancreatic cell developmentGO:000332340.029
purine ribonucleoside monophosphate metabolic processGO:00091671860.029
ephrin receptor signaling pathwayGO:0048013150.029
sensory organ morphogenesisGO:0090596210.029
Zebrafish
response to woundingGO:00096111680.029
Rat
wound healingGO:00420601150.029
negative regulation of hydrolase activityGO:00513461820.029
regulation of nervous system developmentGO:0051960880.029
Mouse Fly
multicellular organismal agingGO:001025930.029
Fly
regulation of purine nucleotide metabolic processGO:19005422640.028
organic acid biosynthetic processGO:0016053970.028
cellular ion homeostasisGO:00068731680.027
neuron projection developmentGO:00311751060.027
Mouse Rat Fly
purine nucleotide catabolic processGO:00061954050.027
energy derivation by oxidation of organic compoundsGO:0015980430.027
positive regulation of catabolic processGO:00098963100.027
cellular response to nutrient levelsGO:0031669690.026
regulation of endopeptidase activityGO:00525481700.026
carbohydrate derivative biosynthetic processGO:19011372070.026
regulation of actin filament based processGO:00329701410.026
compound eye developmentGO:004874910.026
platelet activationGO:0030168440.026
neuron developmentGO:00486661130.026
Zebrafish Mouse Rat Fly
cell cycle phase transitionGO:00447701730.026
positive regulation of protein serine threonine kinase activityGO:00719021190.026
nucleoside phosphate catabolic processGO:19012924120.026
negative regulation of protein metabolic processGO:00512483910.026
anatomical structure formation involved in morphogenesisGO:00486462840.025
Zebrafish Mouse
organophosphate catabolic processGO:00464344300.024
regulation of apoptotic signaling pathwayGO:20012331750.024
chemical homeostasisGO:00488783060.024
positive regulation of protein polymerizationGO:0032273450.024
regulation of phosphatase activityGO:0010921810.024
membrane organizationGO:00610242920.024
Mouse
response to virusGO:00096151260.023
dendritic spine developmentGO:006099660.023
Mouse
positive regulation of protein complex assemblyGO:0031334860.023
negative regulation of cell projection organizationGO:0031345220.023
Mouse
forebrain developmentGO:0030900260.023
Mouse
negative regulation of phosphate metabolic processGO:00459362670.023
response to cytokineGO:00340972320.023
nucleoside monophosphate catabolic processGO:00091251590.023
single organism carbohydrate metabolic processGO:00447231930.023
generation of precursor metabolites and energyGO:0006091680.022
endosomal transportGO:00161971290.022
monocarboxylic acid biosynthetic processGO:0072330670.022
positive regulation of cytoskeleton organizationGO:0051495830.022
nucleoside catabolic processGO:00091644080.022
camera type eye developmentGO:0043010250.022
Zebrafish
coagulationGO:0050817780.022
positive regulation of cell cycleGO:00457871400.022
ribonucleotide biosynthetic processGO:0009260810.022
cellular homeostasisGO:00197251960.021
positive regulation of cysteine type endopeptidase activityGO:2001056790.021
positive regulation of cellular catabolic processGO:00313312840.021
nucleoside triphosphate metabolic processGO:00091414220.021
cell projection assemblyGO:00300311260.021
regulation of reactive oxygen species metabolic processGO:2000377410.021
response to extracellular stimulusGO:0009991850.021
anatomical structure maturationGO:007169590.020
protein foldingGO:0006457380.020
positive regulation of purine nucleotide metabolic processGO:19005442270.020
regulation of intracellular transportGO:00323861950.020
Mouse
ribonucleotide catabolic processGO:00092614050.020
central nervous system developmentGO:00074171230.020
negative regulation of nervous system developmentGO:0051961280.020
Mouse
cellular response to extracellular stimulusGO:0031668720.020
developmental maturationGO:0021700280.019
purine nucleoside catabolic processGO:00061523980.019
taxisGO:00423301570.019
Mouse Fly
atp catabolic processGO:00062001570.019
system processGO:00030083490.019
Mouse
cellular metal ion homeostasisGO:00068751460.019
oocyte developmentGO:004859910.019
peptidyl tyrosine phosphorylationGO:00181081700.019
positive regulation of intracellular transportGO:00323881040.019
Mouse
positive regulation of cellular component biogenesisGO:00440891580.019
peptidyl threonine phosphorylationGO:0018107410.019
Mouse
protein targeting to membraneGO:0006612420.019
Mouse
reproductive processGO:00224141060.019
purine ribonucleotide catabolic processGO:00091544040.019
receptor mediated endocytosisGO:0006898840.019
organ morphogenesisGO:00098871470.019
Zebrafish
reproductionGO:0000003630.018
Worm
regulation of purine nucleotide catabolic processGO:00331212050.018
positive regulation of programmed cell deathGO:00430682490.018
Rat
regulation of jak stat cascadeGO:0046425440.018
Mouse
positive regulation of nucleotide metabolic processGO:00459812300.018
coenzyme metabolic processGO:0006732650.018
microtubule polymerization or depolymerizationGO:0031109370.018
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.017
cell morphogenesis involved in differentiationGO:00009041440.017
Mouse Fly
ribonucleoside monophosphate metabolic processGO:00091611870.017
purine nucleoside triphosphate metabolic processGO:00091444120.017
regulation of protein polymerizationGO:0032271630.017
cellular macromolecular complex assemblyGO:00346223240.017
regulation of cell divisionGO:00513021160.017
response to metal ionGO:0010038840.017
fibroblast proliferationGO:0048144330.016
negative regulation of dephosphorylationGO:0035305630.016
cerebral cortex developmentGO:0021987100.016
Mouse
polysaccharide metabolic processGO:0005976330.016
toxin transportGO:190199840.016
positive regulation of proteolysisGO:00458621420.016
regulation of mapk cascadeGO:00434082620.016
developmental programmed cell deathGO:001062330.016
homotypic cell cell adhesionGO:0034109470.016
positive regulation of cell cycle processGO:00900681060.015
regulation of heart growthGO:006042040.015
positive regulation of cell cycle arrestGO:0071158230.015
ion transmembrane transportGO:00342203380.015
monovalent inorganic cation transportGO:00156721280.015
protein maturationGO:00516042330.015
regulation of chromosome segregationGO:0051983440.015
protein homooligomerizationGO:00512601000.015
protein dephosphorylationGO:0006470810.015
response to radiationGO:00093141510.015
Mouse
regulation of microtubule polymerization or depolymerizationGO:0031110270.015
vasculature developmentGO:00019441810.015
purine ribonucleoside triphosphate catabolic processGO:00092073910.015
cardiovascular system developmentGO:00723582620.015
endocytosisGO:00068971590.015
Rat
renal system developmentGO:0072001630.014
positive regulation of developmental processGO:00510943140.014
neural nucleus developmentGO:0048857470.014
regulation of anatomical structure morphogenesisGO:00226032860.014
Mouse
negative regulation of cell differentiationGO:00455961710.014
Mouse
positive regulation of cell proliferationGO:00082843010.014
apoptotic signaling pathwayGO:00971902680.014
Fly
double strand break repairGO:00063021010.014
dna repairGO:00062811980.014
neuron projection morphogenesisGO:0048812500.014
Mouse Rat Fly
regulation of glycogen catabolic processGO:000598120.014
protein oligomerizationGO:00512591730.014
rna processingGO:00063962550.014
negative regulation of organelle organizationGO:00106391260.014
mitotic cell cycle processGO:19030472860.013
cellular response to acid chemicalGO:0071229440.013
regulation of gtp catabolic processGO:00331241800.013
sister chromatid segregationGO:0000819540.013
regulation of protein catabolic processGO:00421761550.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
cilium organizationGO:0044782680.013
dna damage response signal transduction by p53 class mediatorGO:0030330440.013
regulation of dna metabolic processGO:00510521530.013
axonogenesisGO:0007409310.013
Mouse Fly
steroid metabolic processGO:0008202940.013
sensory perception of painGO:001923340.013
Mouse
response to organonitrogen compoundGO:00102431560.013
Mouse
epithelial cell proliferationGO:00506731280.013
cation transmembrane transportGO:00986552380.013
regulation of developmental growthGO:0048638300.013
Mouse Fly
cell morphogenesis involved in neuron differentiationGO:0048667440.013
Mouse Fly
cellular amide metabolic processGO:0043603690.013
blood vessel developmentGO:00015681720.012
response to lipidGO:00339932060.012
positive regulation of cell differentiationGO:00455972110.012
reproductive structure developmentGO:0048608550.012
regulation of nucleotide metabolic processGO:00061402690.012
negative regulation of cellular protein metabolic processGO:00322693530.012
negative regulation of neurogenesisGO:0050768260.012
Mouse
regulation of ras protein signal transductionGO:00465781550.012
oocyte differentiationGO:000999420.012
regulation of transporter activityGO:0032409820.012
protein catabolic processGO:00301633250.012
morphogenesis of an epitheliumGO:0002009600.012
response to abiotic stimulusGO:00096283360.012
Mouse
vesicle organizationGO:0016050620.012
cellular protein complex assemblyGO:00436231880.012
regulation of extent of cell growthGO:006138790.012
Mouse
regulation of chromosome organizationGO:00330441030.012
osteoblast differentiationGO:0001649920.012
mapk cascadeGO:00001652880.012
eye morphogenesisGO:0048592160.012
Zebrafish
central nervous system projection neuron axonogenesisGO:002195230.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
monocarboxylic acid metabolic processGO:00327871850.012
lipid metabolic processGO:00066293810.012
regulation of cell cycle phase transitionGO:19019871260.012
regulation of cellular component movementGO:00512703340.012
Mouse
sperm egg recognitionGO:003503630.011
proteasomal protein catabolic processGO:00104981760.011
regulation of dephosphorylationGO:0035303960.011
fatty acid biosynthetic processGO:0006633460.011
organelle assemblyGO:00709251760.011
purine ribonucleoside biosynthetic processGO:0046129230.011
metal ion homeostasisGO:00550651690.011
response to nitrogen compoundGO:19016981840.011
Mouse
mitotic cell cycle phase transitionGO:00447721620.011
inorganic cation transmembrane transportGO:00986621940.011
response to starvationGO:0042594590.011
circulatory system developmentGO:00723592620.011
response to oxidative stressGO:00069791210.011
establishment of protein localization to plasma membraneGO:0090002680.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
neuron projection extensionGO:1990138140.011
Mouse
regulation of kinase activityGO:00435493140.011
Mouse
defense responseGO:00069523150.011
Fly
regulation of fibroblast proliferationGO:0048145320.011
regulation of cell morphogenesisGO:00226041530.011
Mouse
organonitrogen compound biosynthetic processGO:19015662000.011
organelle fissionGO:00482851490.011
positive regulation of nucleotide catabolic processGO:00308131850.011
regulation of mitosisGO:0007088630.011
regulation of neuron differentiationGO:0045664700.011
Mouse
cellular response to external stimulusGO:00714961110.011
ras protein signal transductionGO:0007265730.011
guanosine containing compound metabolic processGO:19010682440.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
regulation of mitotic cell cycleGO:00073461890.011
cofactor metabolic processGO:0051186870.011
regulation of cellular carbohydrate metabolic processGO:0010675470.010
axon developmentGO:0061564340.010
Mouse Fly
glycoprotein metabolic processGO:00091001100.010
glycoprotein biosynthetic processGO:0009101910.010
determination of adult lifespanGO:000834020.010
Fly
neural retina developmentGO:000340780.010
Zebrafish
organic hydroxy compound metabolic processGO:19016151470.010
Fly
positive regulation of protein catabolic processGO:0045732750.010
protein importGO:00170381300.010
myeloid cell differentiationGO:00300991170.010

CDK5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.028
disease of cellular proliferationDOID:145661740.025
central nervous system diseaseDOID:3311860.018
nervous system diseaseDOID:8634310.018
neurodegenerative diseaseDOID:12891020.018
hematopoietic system diseaseDOID:741000.012
integumentary system diseaseDOID:16430.010
skin diseaseDOID:37330.010