Homo sapiens

0 known processes

DMBX1

diencephalon/mesencephalon homeobox 1

(Aliases: MBX,OTX3,PAXB)

DMBX1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.076
organ formationGO:004864530.075
system processGO:00030083490.066
cellular amino acid metabolic processGO:00065201160.062
regulation of cellular ketone metabolic processGO:0010565500.062
neuron fate commitmentGO:004866320.057
anatomical structure formation involved in morphogenesisGO:00486462840.056
amine metabolic processGO:0009308440.056
circulatory system developmentGO:00723592620.055
regulation of cell differentiationGO:00455953930.054
Zebrafish
regulation of cellular amine metabolic processGO:0033238110.053
regulation of cellular amino acid metabolic processGO:000652160.050
cardiovascular system developmentGO:00723582620.049
cellular ketone metabolic processGO:0042180800.049
cellular amine metabolic processGO:0044106410.047
response to abiotic stimulusGO:00096283360.047
positive regulation of cellular amino acid metabolic processGO:004576430.047
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.047
Mouse
cell fate determinationGO:000170930.046
specification of organ identityGO:001009230.046
transmembrane transportGO:00550853990.046
regulation of anatomical structure morphogenesisGO:00226032860.046
negative regulation of multicellular organismal processGO:00512413170.046
response to oxygen containing compoundGO:19017003690.045
nervous system developmentGO:00073992930.043
Zebrafish Mouse
cell developmentGO:00484683280.043
Zebrafish
hindbrain developmentGO:003090230.042
organ morphogenesisGO:00098871470.040
cellular component morphogenesisGO:00329893140.039
cellular response to endogenous stimulusGO:00714953360.039
multicellular organismal agingGO:001025930.037
locomotory behaviorGO:000762610.037
Mouse
cell morphogenesisGO:00009022960.034
regulation of cell cycleGO:00517263930.034
Zebrafish
segmentationGO:003528240.034
epithelium developmentGO:00604292270.034
determination of adult lifespanGO:000834020.034
positive regulation of cellular amine metabolic processGO:003324070.032
positive regulation of cell differentiationGO:00455972110.032
negative regulation of cell deathGO:00605483450.032
cardiac cell fate determinationGO:006091330.032
positive regulation of cell proliferationGO:00082843010.031
inner ear morphogenesisGO:004247240.031
positive regulation of hydrolase activityGO:00513453310.031
neurogenesisGO:00220081690.031
Zebrafish
purine ribonucleoside metabolic processGO:00461284370.031
negative regulation of protein metabolic processGO:00512483910.031
ras protein signal transductionGO:0007265730.031
spinal cord developmentGO:002151040.030
negative regulation of apoptotic processGO:00430663160.030
positive regulation of developmental processGO:00510943140.030
immune responseGO:00069553070.029
morphogenesis of embryonic epitheliumGO:001633140.029
cell adhesionGO:00071553250.029
lipid metabolic processGO:00066293810.029
cranial nerve developmentGO:002154540.029
forebrain generation of neuronsGO:002187230.028
positive regulation of phosphorylationGO:00423273940.028
cell projection organizationGO:00300302520.028
negative regulation of cell differentiationGO:00455961710.028
actin filament based processGO:00300292240.028
cellular response to dna damage stimulusGO:00069743790.028
regulation of cellular component movementGO:00512703340.027
negative regulation of cellular protein metabolic processGO:00322693530.027
small molecule biosynthetic processGO:00442831570.027
central nervous system developmentGO:00074171230.027
Zebrafish Mouse
female gamete generationGO:000729220.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
defense responseGO:00069523150.026
oogenesisGO:004847720.026
metencephalon developmentGO:002203720.026
generation of neuronsGO:00486991520.026
Zebrafish
limbic system developmentGO:002176130.025
cellular response to oxygen containing compoundGO:19017012760.025
secretionGO:00469032540.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
purine nucleoside catabolic processGO:00061523980.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
mitotic cell cycleGO:00002783260.025
cellular macromolecule catabolic processGO:00442653800.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
memoryGO:000761330.025
negative regulation of phosphorus metabolic processGO:00105632670.024
blastoderm segmentationGO:000735020.024
biological adhesionGO:00226103310.024
forebrain regionalizationGO:002187130.024
purine ribonucleoside triphosphate metabolic processGO:00092054110.024
small gtpase mediated signal transductionGO:0007264780.024
nucleotide catabolic processGO:00091664080.024
negative regulation of programmed cell deathGO:00430693210.024
negative regulation of catalytic activityGO:00430863350.024
blood vessel developmentGO:00015681720.024
cation transmembrane transportGO:00986552380.024
nucleoside triphosphate metabolic processGO:00091414220.024
protein localization to organelleGO:00333652800.024
startle responseGO:000196430.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
nucleoside catabolic processGO:00091644080.024
ribonucleotide catabolic processGO:00092614050.024
regulation of cellular response to stressGO:00801352440.023
purine ribonucleotide catabolic processGO:00091544040.023
epithelial cell differentiationGO:00308551410.023
nucleoside phosphate catabolic processGO:19012924120.023
regulation of cell developmentGO:00602841610.023
Zebrafish
response to external biotic stimulusGO:00432072610.023
glycosyl compound catabolic processGO:19016584130.023
immune system developmentGO:00025201950.023
organophosphate catabolic processGO:00464344300.023
anterior posterior axis specificationGO:000994820.023
ribonucleoside catabolic processGO:00424544060.023
negative regulation of developmental processGO:00510932470.023
positive regulation of cellular component organizationGO:00511303760.023
positive regulation of transportGO:00510503360.023
regulation of cell cycle processGO:00105642660.022
cell cell signalingGO:00072671550.022
response to biotic stimulusGO:00096072760.022
regulation of endopeptidase activityGO:00525481700.022
regulation of proteolysisGO:00301622930.022
brain developmentGO:0007420970.022
Zebrafish Mouse
purine containing compound catabolic processGO:00725234110.022
neuromuscular junction developmentGO:000752830.022
positive regulation of synaptic transmissionGO:005080640.022
inorganic cation transmembrane transportGO:00986621940.022
innate immune responseGO:00450871780.022
cellular lipid metabolic processGO:00442553030.022
positive regulation of protein phosphorylationGO:00019343130.022
regulation of locomotionGO:00400123290.022
regenerationGO:003109940.022
photoreceptor cell differentiationGO:004653020.022
purine ribonucleoside catabolic processGO:00461303980.022
nucleoside triphosphate catabolic processGO:00091433940.022
embryonic epithelial tube formationGO:000183840.022
compound eye developmentGO:004874910.022
purine nucleotide catabolic processGO:00061954050.022
regulation of neural precursor cell proliferationGO:200017740.021
vesicle mediated transportGO:00161923710.021
neurological system processGO:00508771630.021
protein maturationGO:00516042330.021
lipid biosynthetic processGO:00086101770.021
nitrogen compound transportGO:00717051910.021
regulation of transferase activityGO:00513383550.021
response to lipidGO:00339932060.021
single organism cellular localizationGO:19025803320.021
positive regulation of cellular catabolic processGO:00313312840.021
cardiac right ventricle morphogenesisGO:000321530.021
regulation of cytokine productionGO:00018172320.021
negative regulation of cell proliferationGO:00082852280.021
mitotic cell cycle processGO:19030472860.021
cytoplasmic transportGO:00164823790.021
carbohydrate derivative biosynthetic processGO:19011372070.021
ion transmembrane transportGO:00342203380.021
detection of stimulusGO:0051606850.021
cell morphogenesis involved in differentiationGO:00009041440.021
positive regulation of cell deathGO:00109422630.021
positive regulation of apoptotic processGO:00430652460.021
negative regulation of cell cycleGO:00457861930.020
negative regulation of phosphate metabolic processGO:00459362670.020
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.020
protein catabolic processGO:00301633250.020
chromatin organizationGO:00063253510.020
ion homeostasisGO:00508012300.020
signal transduction by phosphorylationGO:00230142970.020
regulation of protein kinase activityGO:00458592890.020
regulation of peptidase activityGO:00525471800.020
forelimb morphogenesisGO:003513640.020
monocarboxylic acid metabolic processGO:00327871850.020
cell growthGO:00160491600.020
positive regulation of tooth mineralizationGO:007017220.020
forebrain neuron differentiationGO:002187930.020
cellular cation homeostasisGO:00300031630.020
regulation of cell motilityGO:20001452990.020
cation transportGO:00068123310.019
positive regulation of catabolic processGO:00098963100.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
cerebellum developmentGO:002154920.019
positive regulation of programmed cell deathGO:00430682490.019
positive regulation of hormone biosynthetic processGO:004688640.019
muscle system processGO:0003012810.019
negative regulation of cellular component organizationGO:00511292350.019
hematopoietic or lymphoid organ developmentGO:00485341860.019
cellular homeostasisGO:00197251960.019
regulation of kinase activityGO:00435493140.019
actin mediated cell contractionGO:0070252120.019
matingGO:000761810.019
response to other organismGO:00517072610.019
cytokine productionGO:00018162470.019
regulation of cell morphogenesisGO:00226041530.019
inorganic ion transmembrane transportGO:00986602310.019
cation homeostasisGO:00550801890.018
regulation of neurogenesisGO:0050767820.018
Zebrafish
micturitionGO:006007330.018
response to hormoneGO:00097251750.018
actin cytoskeleton organizationGO:00300362070.018
regulation of cell migrationGO:00303342890.018
cell differentiation in spinal cordGO:002151510.018
neuroblast proliferationGO:000740540.018
secretion by cellGO:00329402260.018
response to organonitrogen compoundGO:00102431560.018
protein processingGO:00164852260.018
response to organic cyclic compoundGO:00140702040.018
head developmentGO:00603221080.018
Zebrafish Mouse
oxidation reduction processGO:00551143960.018
heart developmentGO:0007507950.018
muscle contractionGO:0006936730.018
chromatin modificationGO:00165682980.018
positive regulation of protein kinase activityGO:00458601900.018
neuron differentiationGO:00301821380.017
membrane organizationGO:00610242920.017
chemical homeostasisGO:00488783060.017
posttranscriptional regulation of gene expressionGO:00106082130.017
rho protein signal transductionGO:0007266260.017
nerve developmentGO:002167540.017
positive regulation of immune system processGO:00026842830.017
mesonephric duct developmentGO:007217730.017
epithelial tube branching involved in lung morphogenesisGO:006044140.017
metal ion transportGO:00300012720.017
cardiac muscle cell contractionGO:008600340.017
chemotaxisGO:00069351570.017
behaviorGO:00076101120.017
Mouse
regulation of mitotic cell cycleGO:00073461890.017
hemopoiesisGO:00300971800.017
single organism membrane organizationGO:00448022680.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
positive regulation of odontogenesisGO:004248230.017
response to nitrogen compoundGO:19016981840.017
adult locomotory behaviorGO:000834410.017
Mouse
cellular response to hormone stimulusGO:00328701250.017
regulation of response to external stimulusGO:00321012220.017
regulation of hormone levelsGO:00108171250.017
cell divisionGO:00513011680.017
actin filament based movementGO:0030048170.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
positive regulation of secretionGO:00510471160.016
neural tube formationGO:000184130.016
regulation of secretionGO:00510461940.016
thymus developmentGO:004853830.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
stem cell differentiationGO:0048863930.016
vasculature developmentGO:00019441810.016
nucleoside monophosphate metabolic processGO:00091231910.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
peripheral nervous system developmentGO:000742220.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
regulation of protein localizationGO:00328802960.016
menstrual cycle phaseGO:002260120.016
tripartite regional subdivisionGO:000735120.016
regulation of protein transportGO:00512232130.016
cell projection morphogenesisGO:00488581290.016
motor neuron axon guidanceGO:000804520.016
cellular protein catabolic processGO:00442572610.016
atp metabolic processGO:00460341760.016
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.016
growthGO:00400072020.016
Mouse
positive regulation of cell cycleGO:00457871400.016
negative regulation of cellular amine metabolic processGO:003323930.016
regulation of cell growthGO:00015581350.016
oocyte developmentGO:004859910.016
ossificationGO:00015031210.016
oocyte differentiationGO:000999420.016
negative regulation of protein modification processGO:00314002000.016
regulation of cellular component biogenesisGO:00440872810.016
striated muscle contractionGO:0006941520.016
regulation of secretion by cellGO:19035301770.016
cell cycle phase transitionGO:00447701730.016
regulation of nucleoside metabolic processGO:00091182090.016
heart formationGO:006091420.016
mapk cascadeGO:00001652880.016
positive regulation of cell developmentGO:0010720920.016
alcohol metabolic processGO:00060661140.015
cell part morphogenesisGO:00329901370.015
spermatid differentiationGO:004851540.015
negative regulation of intracellular signal transductionGO:19025321830.015
blood vessel morphogenesisGO:00485141620.015
dephosphorylationGO:00163112090.015
apoptotic signaling pathwayGO:00971902680.015
regulation of nucleotide metabolic processGO:00061402690.015
organic hydroxy compound metabolic processGO:19016151470.015
associative learningGO:000830610.015
negative regulation of hydrolase activityGO:00513461820.015
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.015
anion transportGO:00068201610.015
cartilage condensationGO:000150210.015
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of mapk cascadeGO:00434082620.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
cellular chemical homeostasisGO:00550821800.015
organonitrogen compound biosynthetic processGO:19015662000.015
cellular ion homeostasisGO:00068731680.015
developmental programmed cell deathGO:001062330.015
regulation of growthGO:00400081650.015
negative regulation of phosphorylationGO:00423261740.015
regulation of immune responseGO:00507762010.015
sensory perceptionGO:00076001030.015
carboxylic acid biosynthetic processGO:0046394970.015
dna repairGO:00062811980.015
embryonic morphogenesisGO:0048598850.015
maintenance of locationGO:00512351120.015
cell substrate adhesionGO:00315891320.015
detection of chemical stimulusGO:0009593550.015
hair follicle morphogenesisGO:003106920.015
cellular response to nitrogen compoundGO:19016991440.015
primary neural tube formationGO:001402030.015
response to woundingGO:00096111680.015
monovalent inorganic cation transportGO:00156721280.015
positive regulation of nucleotide metabolic processGO:00459812300.015
microtubule based processGO:00070172100.015
positive regulation of mapk cascadeGO:00434101900.015
pituitary gland developmentGO:002198320.015
single organism cell adhesionGO:00986021790.015
embryonic camera type eye developmentGO:003107620.015
positive regulation of transferase activityGO:00513472270.015
regulation of dna metabolic processGO:00510521530.014
visual behaviorGO:000763220.014
heart field specificationGO:000312820.014
intracellular protein transportGO:00068862700.014
nuclear transportGO:00511691790.014
taxisGO:00423301570.014
response to radiationGO:00093141510.014
syncytium formation by plasma membrane fusionGO:000076820.014
cellular macromolecular complex assemblyGO:00346223240.014
positive regulation of neural precursor cell proliferationGO:200017920.014
g protein coupled receptor signaling pathwayGO:00071862070.014
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333740.014
protein ubiquitinationGO:00165673140.014
ventral spinal cord developmentGO:002151710.014
negative regulation of cell developmentGO:0010721480.014
regulation of meiotic cell cycleGO:005144540.014
tube closureGO:006060630.014
muscle structure developmentGO:0061061980.014
cell activationGO:00017752130.014
organic acid biosynthetic processGO:0016053970.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
cellular metal ion homeostasisGO:00068751460.014
neuron developmentGO:00486661130.014
cellular response to growth factor stimulusGO:00713631970.014
regulation of purine nucleotide catabolic processGO:00331212050.014
reactive oxygen species biosynthetic processGO:190340940.014
protein oligomerizationGO:00512591730.014
response to growth factorGO:00708482050.014
regulation of membrane potentialGO:0042391950.014
lung alveolus developmentGO:004828640.014
endomembrane system organizationGO:00102561960.014
epithelial cell proliferationGO:00506731280.014
positive regulation of organelle organizationGO:00106381950.014
nucleocytoplasmic transportGO:00069131760.014
anterior posterior axis specification embryoGO:000859520.014
positive regulation of secretion by cellGO:19035321080.014
positive regulation of kinase activityGO:00336742040.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
response to fungusGO:000962040.014
regulation of nucleotide catabolic processGO:00308112050.014
response to inorganic substanceGO:00100351270.014
negative regulation of protein phosphorylationGO:00019331400.014
testosterone biosynthetic processGO:006137020.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
negative regulation of locomotionGO:00400131180.013
reactive nitrogen species metabolic processGO:200105730.013
tissue regenerationGO:004224630.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
nucleoside monophosphate catabolic processGO:00091251590.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
follicle stimulating hormone secretionGO:004688430.013
negative regulation of protein processingGO:00109551420.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
cellular response to organonitrogen compoundGO:00714171240.013
positive regulation of cytokine productionGO:00018191670.013
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.013
potassium ion transmembrane transportGO:0071805600.013
response to hypoxiaGO:0001666960.013
positive regulation of proteolysisGO:00458621420.013
negative regulation of protein maturationGO:19033181420.013
wnt signaling pathwayGO:00160551560.013
positive regulation of cell motilityGO:20001471770.013
angiogenesisGO:00015251470.013
positive regulation of locomotionGO:00400171860.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of cell morphogenesis involved in differentiationGO:0010769830.013
regulation of nervous system developmentGO:0051960880.013
Zebrafish
metal ion homeostasisGO:00550651690.013
protein modification by small protein conjugationGO:00324463420.013
cellular response to abiotic stimulusGO:00712141170.013
positive regulation of cellular component movementGO:00512721810.013
regulation of establishment of protein localizationGO:00702012420.013
reactive oxygen species metabolic processGO:0072593750.013
sex determinationGO:000753030.013
spermatid developmentGO:000728640.013
positive regulation of protein transportGO:00512221350.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
mitotic cell cycle phase transitionGO:00447721620.013
negative regulation of cellular component movementGO:00512711060.013
hippocampus developmentGO:002176610.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
sensory perception of painGO:001923340.013
myoblast fusionGO:000752010.013
peptidyl tyrosine phosphorylationGO:00181081700.013
guanosine containing compound catabolic processGO:19010692390.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
tube developmentGO:00352951250.013
regulation of epithelial cell proliferationGO:00506781130.013
sensory organ developmentGO:0007423520.013
Zebrafish
negative regulation of cell migrationGO:00303361020.013
positive regulation of cell migrationGO:00303351720.013
protein localization to nucleusGO:00345041360.013
cell fate commitment involved in pattern specificationGO:006058110.013
covalent chromatin modificationGO:00165692540.013
positive regulation of steroid hormone biosynthetic processGO:009003120.013
regulation of protein catabolic processGO:00421761550.013
positive regulation of aldosterone biosynthetic processGO:003234920.013
embryo developmentGO:00097901230.013
neuron projection developmentGO:00311751060.012
cell proliferation in forebrainGO:002184610.012
glycerolipid metabolic processGO:00464861070.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
aortic valve developmentGO:000317630.012
regulation of testosterone biosynthetic processGO:200022420.012
neural tube closureGO:000184330.012
negative regulation of cell motilityGO:20001461040.012
mesenchymal cell developmentGO:0014031500.012
regulation of synaptic plasticityGO:004816730.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of intracellular transportGO:00323861950.012
cell aggregationGO:009874310.012
cellular response to lipidGO:00713961270.012
hindlimb morphogenesisGO:003513720.012
regulation of protein maturationGO:19033171500.012
cd8 positive alpha beta t cell differentiation involved in immune responseGO:000230210.012
guanosine containing compound metabolic processGO:19010682440.012
osteoblast differentiationGO:0001649920.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
proteasomal protein catabolic processGO:00104981760.012
embryonic camera type eye morphogenesisGO:004859620.012
positive regulation of cellular component biogenesisGO:00440891580.012
soft palate developmentGO:006002330.012
regulation of protein serine threonine kinase activityGO:00719001790.012
regulation of cell projection organizationGO:00313441070.012
atp catabolic processGO:00062001570.012
response to axon injuryGO:004867810.012
tissue morphogenesisGO:0048729960.012
positive regulation of endopeptidase activityGO:0010950840.012
positive regulation of nucleotide catabolic processGO:00308131850.012
glycoprotein metabolic processGO:00091001100.012
gtp catabolic processGO:00061842370.012
negative regulation of proteolysisGO:00458611320.012
regulation of cardiac muscle tissue growthGO:005502140.012
postsynaptic membrane organizationGO:000194120.012
gtp metabolic processGO:00460392390.012
response to oxygen levelsGO:00704821000.012
reproductive processGO:00224141060.012
visual learningGO:000854210.012
carbohydrate metabolic processGO:00059752070.012
establishment of protein localization to organelleGO:00725941720.012
organelle assemblyGO:00709251760.012
single organism reproductive processGO:0044702980.012
regulation of cell adhesionGO:00301551660.012
eye photoreceptor cell differentiationGO:000175420.012
neural tube patterningGO:002153220.012
somitogenesisGO:000175620.012
regulation of protein processingGO:00706131500.012
outflow tract septum morphogenesisGO:000314840.012
single organismal cell cell adhesionGO:00163371480.012
cellular potassium ion transportGO:0071804600.012
potassium ion transportGO:0006813620.012
regulation of ion transportGO:00432691890.012
sensory perception of smellGO:000760820.012
oxidative stress induced premature senescenceGO:009040330.012
calcium ion homeostasisGO:00550741220.012
protein targetingGO:00066051870.012
negative regulation of male gonad developmentGO:200001910.012
stem cell developmentGO:0048864690.012
hormone metabolic processGO:0042445610.012
microtubule cytoskeleton organizationGO:00002261760.012
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.011
defense response to fungusGO:005083240.011
single organism carbohydrate metabolic processGO:00447231930.011
regulation of neuron differentiationGO:0045664700.011
regulation of male gonad developmentGO:200001840.011
detection of muramyl dipeptideGO:003249810.011

DMBX1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.033
musculoskeletal system diseaseDOID:172230.026
inherited metabolic disorderDOID:6552420.024
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.020
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.017
retinal diseaseDOID:56791180.017
central nervous system diseaseDOID:3311860.016
disease of cellular proliferationDOID:145661740.014
retinal degenerationDOID:8466890.014
cardiovascular system diseaseDOID:12871060.013
cancerDOID:1621670.013
organ system cancerDOID:00506861640.012