Homo sapiens

226 known processes

HSPD1

heat shock 60kDa protein 1 (chaperonin)

(Aliases: HuCHA60,GROEL,HSP-60,HLD4,SPG13,HSP60,CPN60,HSP65)

HSPD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein refoldingGO:0042026140.998
nucleoside monophosphate metabolic processGO:00091231910.984
protein foldingGO:0006457380.978
determination of adult lifespanGO:000834020.951
post embryonic developmentGO:000979120.941
Worm
de novo protein foldingGO:000645820.912
Rat
mitochondrion organizationGO:00070051560.903
Worm Fly
de novo posttranslational protein foldingGO:005108420.876
Rat
negative regulation of cell deathGO:00605483450.852
purine ribonucleoside monophosphate metabolic processGO:00091671860.816
purine ribonucleoside monophosphate catabolic processGO:00091691580.752
oxidation reduction processGO:00551143960.743
negative regulation of programmed cell deathGO:00430693210.720
chaperone mediated protein folding requiring cofactorGO:005108510.700
Rat
ribonucleoprotein complex localizationGO:007116640.641
chaperone cofactor dependent protein refoldingGO:007038940.616
growthGO:00400072020.598
Zebrafish
positive regulation of programmed cell deathGO:00430682490.596
intracellular protein transmembrane importGO:0044743230.591
positive regulation of apoptotic processGO:00430652460.588
regenerationGO:003109940.585
Zebrafish
ribonucleoside monophosphate catabolic processGO:00091581580.565
multicellular organismal agingGO:001025930.536
transmembrane transportGO:00550853990.493
embryo developmentGO:00097901230.490
Worm
ribonucleoside triphosphate metabolic processGO:00091994120.458
ribonucleotide catabolic processGO:00092614050.455
endoplasmic reticulum unfolded protein responseGO:0030968160.443
Worm
negative regulation of apoptotic processGO:00430663160.440
purine nucleoside monophosphate metabolic processGO:00091261860.440
mitochondrial membrane organizationGO:0007006400.411
intracellular protein transmembrane transportGO:0065002240.379
nucleoside catabolic processGO:00091644080.367
response to nitrogen compoundGO:19016981840.364
Rat
positive regulation of hydrolase activityGO:00513453310.357
purine ribonucleoside metabolic processGO:00461284370.351
cytoplasmic transportGO:00164823790.345
cofactor metabolic processGO:0051186870.335
purine nucleotide catabolic processGO:00061954050.334
purine nucleoside triphosphate metabolic processGO:00091444120.332
atp metabolic processGO:00460341760.326
ribonucleoside monophosphate metabolic processGO:00091611870.324
nuclear transportGO:00511691790.323
protein importGO:00170381300.320
reproductive structure developmentGO:0048608550.281
coenzyme metabolic processGO:0006732650.273
cellular amino acid metabolic processGO:00065201160.265
regulation of atp metabolic processGO:1903578290.261
agingGO:0007568660.257
multi organism cellular processGO:00447641560.253
anterior posterior axis specificationGO:000994820.249
establishment of protein localization to organelleGO:00725941720.246
nucleoside triphosphate catabolic processGO:00091433940.242
vesicle mediated transportGO:00161923710.240
protein import into mitochondrial matrixGO:003015010.235
receptor mediated endocytosisGO:0006898840.234
system processGO:00030083490.232
nucleocytoplasmic transportGO:00069131760.215
purine ribonucleotide catabolic processGO:00091544040.213
immune system developmentGO:00025201950.212
regulation of endopeptidase activityGO:00525481700.206
ossificationGO:00015031210.202
positive regulation of cell deathGO:00109422630.191
purine ribonucleoside triphosphate metabolic processGO:00092054110.187
toxin transportGO:190199840.174
osteoblast differentiationGO:0001649920.167
single organism cellular localizationGO:19025803320.159
regulation of protein transportGO:00512232130.158
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.150
regulation of transferase activityGO:00513383550.145
negative regulation of cell proliferationGO:00082852280.144
purine nucleoside monophosphate catabolic processGO:00091281580.142
energy derivation by oxidation of organic compoundsGO:0015980430.138
posttranscriptional regulation of gene expressionGO:00106082130.136
cell growthGO:00160491600.129
purine ribonucleoside catabolic processGO:00461303980.129
intracellular protein transportGO:00068862700.127
mitochondrial transportGO:0006839600.126
protein oligomerizationGO:00512591730.121
nucleoside triphosphate metabolic processGO:00091414220.120
regulation of protein kinase activityGO:00458592890.120
protein targetingGO:00066051870.118
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.113
nuclear exportGO:0051168690.113
response to endoplasmic reticulum stressGO:0034976490.112
Worm
negative regulation of neuron apoptotic processGO:0043524230.112
Rat
nucleotide catabolic processGO:00091664080.110
response to woundingGO:00096111680.109
Zebrafish Rat
oogenesisGO:004847720.109
cellular response to nitrogen compoundGO:19016991440.108
cell cell recognitionGO:000998840.107
response to unfolded proteinGO:0006986240.106
reproductionGO:0000003630.105
Worm
regulation of cell growthGO:00015581350.098
nucleoside monophosphate catabolic processGO:00091251590.097
protein transmembrane transportGO:0071806250.096
cellular response to unfolded proteinGO:0034620160.091
Worm
cellular response to topologically incorrect proteinGO:0035967190.088
Worm
positive regulation of developmental processGO:00510943140.087
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.084
nucleoside phosphate catabolic processGO:19012924120.082
female gamete generationGO:000729220.081
hemopoiesisGO:00300971800.080
purine containing compound catabolic processGO:00725234110.080
purine nucleoside triphosphate catabolic processGO:00091463920.079
response to temperature stimulusGO:0009266220.078
Rat Fly
rrna metabolic processGO:0016072400.078
generation of precursor metabolites and energyGO:0006091680.077
cellular macromolecule catabolic processGO:00442653800.075
glycosyl compound catabolic processGO:19016584130.073
cotranslational protein targeting to membraneGO:000661320.073
cellular macromolecular complex assemblyGO:00346223240.073
chemical homeostasisGO:00488783060.072
response to abiotic stimulusGO:00096283360.071
Rat Fly
purine ribonucleoside triphosphate catabolic processGO:00092073910.071
cation homeostasisGO:00550801890.069
hematopoietic or lymphoid organ developmentGO:00485341860.069
regulation of neuron apoptotic processGO:0043523350.068
Rat
apoptotic signaling pathwayGO:00971902680.067
cellular response to oxygen containing compoundGO:19017012760.067
regulation of growthGO:00400081650.066
cellular response to organonitrogen compoundGO:00714171240.066
nucleotide biosynthetic processGO:00091651090.065
single organism reproductive processGO:0044702980.065
apoptotic mitochondrial changesGO:0008637570.064
reproductive processGO:00224141060.064
amine metabolic processGO:0009308440.062
cellular response to oxidative stressGO:0034599850.061
gland developmentGO:0048732480.060
regulation of ion transportGO:00432691890.060
cellular response to cytokine stimulusGO:00713451810.059
metal ion homeostasisGO:00550651690.059
response to hormoneGO:00097251750.059
Rat
cellular lipid metabolic processGO:00442553030.059
neuron deathGO:0070997650.058
Rat
response to oxidative stressGO:00069791210.057
Rat
cellular protein complex assemblyGO:00436231880.057
sulfur compound metabolic processGO:00067901010.055
small gtpase mediated signal transductionGO:0007264780.054
cellular amine metabolic processGO:0044106410.054
negative regulation of cell growthGO:0030308830.053
lipid metabolic processGO:00066293810.052
embryo development ending in birth or egg hatchingGO:0009792340.052
Worm
regulation of cell cycleGO:00517263930.050
ribonucleoside catabolic processGO:00424544060.050
response to drugGO:0042493810.049
Rat
reactive oxygen species metabolic processGO:0072593750.048
regulation of mitochondrial membrane potentialGO:0051881230.047
nervous system developmentGO:00073992930.046
reproductive system developmentGO:0061458560.046
response to virusGO:00096151260.046
ras protein signal transductionGO:0007265730.046
symbiosis encompassing mutualism through parasitismGO:00444031560.046
tissue regenerationGO:004224630.044
Zebrafish
response to cytokineGO:00340972320.044
regulation of membrane potentialGO:0042391950.044
spindle assembly involved in mitosisGO:0090307120.043
regulation of kinase activityGO:00435493140.042
organ morphogenesisGO:00098871470.042
rna localizationGO:0006403410.041
regulation of apoptotic signaling pathwayGO:20012331750.041
purine nucleoside catabolic processGO:00061523980.041
nitrogen compound transportGO:00717051910.041
cellular component morphogenesisGO:00329893140.040
cellular response to peptide hormone stimulusGO:0071375560.040
protein targeting to nucleusGO:00447441040.039
organophosphate catabolic processGO:00464344300.038
rrna containing ribonucleoprotein complex export from nucleusGO:007142840.038
regulation of multi organism processGO:00439001570.038
positive regulation of cell differentiationGO:00455972110.038
divalent inorganic cation homeostasisGO:00725071360.038
regulation of cell adhesionGO:00301551660.037
small nucleolar ribonucleoprotein complex assemblyGO:000049130.037
single organism membrane organizationGO:00448022680.037
regulation of protein localizationGO:00328802960.037
ncrna processingGO:0034470830.037
protein localization to organelleGO:00333652800.036
ribonucleoside triphosphate catabolic processGO:00092033910.036
membrane organizationGO:00610242920.035
dna catabolic processGO:0006308490.035
protein homooligomerizationGO:00512601000.035
regulation of dna metabolic processGO:00510521530.035
negative regulation of cellular protein metabolic processGO:00322693530.035
cell type specific apoptotic processGO:00972851250.034
Rat
regulation of cytokine productionGO:00018172320.034
i kappab kinase nf kappab signalingGO:00072491660.033
establishment of protein localization to mitochondrial membraneGO:009015170.033
organonitrogen compound biosynthetic processGO:19015662000.033
innate immune responseGO:00450871780.033
negative regulation of protein metabolic processGO:00512483910.033
carboxylic acid catabolic processGO:0046395710.032
immune responseGO:00069553070.032
renal system developmentGO:0072001630.032
development of primary sexual characteristicsGO:0045137350.032
regulation of establishment of protein localizationGO:00702012420.031
gonad developmentGO:0008406340.031
positive regulation of purine nucleotide metabolic processGO:19005442270.031
alpha amino acid metabolic processGO:1901605720.031
positive regulation of cellular catabolic processGO:00313312840.030
regulation of endodeoxyribonuclease activityGO:003207130.030
atp catabolic processGO:00062001570.029
binding of sperm to zona pellucidaGO:000733930.029
organelle assemblyGO:00709251760.029
negative regulation of protein phosphorylationGO:00019331400.029
negative regulation of bindingGO:0051100570.029
er nucleus signaling pathwayGO:0006984230.028
Worm
anterior posterior axis specification embryoGO:000859520.028
establishment of protein localization to membraneGO:00901501210.028
response to heatGO:0009408210.028
Rat Fly
single organism nuclear importGO:19025931040.028
sex differentiationGO:0007548450.028
microtubule cytoskeleton organizationGO:00002261760.028
negative regulation of protein modification processGO:00314002000.028
behaviorGO:00076101120.027
cellular metal ion homeostasisGO:00068751460.027
response to extracellular stimulusGO:0009991850.027
chaperone mediated protein complex assemblyGO:005113190.027
regulation of peptidase activityGO:00525471800.026
mitotic cell cycle processGO:19030472860.026
protein processingGO:00164852260.026
regulation of translational initiation in response to stressGO:004355810.026
nls bearing protein import into nucleusGO:000660720.026
regulation of sequence specific dna binding transcription factor activityGO:00510902110.025
organic acid biosynthetic processGO:0016053970.025
positive regulation of protein secretionGO:0050714600.025
negative regulation of catalytic activityGO:00430863350.025
negative regulation of multi organism processGO:0043901920.025
rrna processingGO:0006364350.025
response to oxygen containing compoundGO:19017003690.025
Rat
positive regulation of growthGO:0045927580.024
regulation of purine nucleotide catabolic processGO:00331212050.024
regulation of translation in response to stressGO:004355530.024
regulation of cell differentiationGO:00455953930.024
positive regulation of apoptotic signaling pathwayGO:2001235700.024
secretion by cellGO:00329402260.024
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.023
cellular cation homeostasisGO:00300031630.023
blastoderm segmentationGO:000735020.023
endocytosisGO:00068971590.023
pyrimidine ribonucleoside metabolic processGO:0046131110.023
nuclear importGO:00511701060.023
ribosomal large subunit export from nucleusGO:000005530.022
chordate embryonic developmentGO:0043009340.022
gtp catabolic processGO:00061842370.022
rna interferenceGO:001624640.022
gmp metabolic processGO:004603740.022
negative regulation of phosphate metabolic processGO:00459362670.022
multicellular organismal reproductive processGO:0048609400.021
epithelial cell differentiationGO:00308551410.021
myosin filament organizationGO:003103320.021
peptidyl proline modificationGO:0018208150.021
cellular ion homeostasisGO:00068731680.021
positive regulation of cell motilityGO:20001471770.021
myeloid cell differentiationGO:00300991170.021
positive regulation of catabolic processGO:00098963100.021
mitotic cell cycleGO:00002783260.020
protein export from nucleusGO:0006611290.020
neurogenesisGO:00220081690.020
negative regulation of phosphorus metabolic processGO:00105632670.020
positive regulation of cytokine productionGO:00018191670.020
positive regulation of cell proliferationGO:00082843010.019
monocarboxylic acid metabolic processGO:00327871850.019
circulatory system processGO:00030131130.019
embryonic organ developmentGO:0048568360.019
response to organic cyclic compoundGO:00140702040.019
Rat
embryonic morphogenesisGO:0048598850.019
response to peptideGO:1901652650.018
mapk cascadeGO:00001652880.018
negative regulation of endopeptidase activityGO:0010951840.018
striated muscle myosin thick filament assemblyGO:007168820.018
neuron apoptotic processGO:0051402390.018
Rat
mitochondrial translationGO:0032543170.018
lipid localizationGO:00108761060.018
wound healingGO:00420601150.018
Zebrafish
secretionGO:00469032540.018
response to hypoxiaGO:0001666960.018
Rat
rna export from nucleusGO:0006405330.018
interspecies interaction between organismsGO:00444191560.017
multi organism reproductive processGO:0044703540.017
microtubule based processGO:00070172100.017
mrna processingGO:00063971330.017
rna processingGO:00063962550.017
brain developmentGO:0007420970.017
activation of immune responseGO:00022531140.017
gamete generationGO:0007276250.017
regulation of purine nucleotide metabolic processGO:19005422640.017
response to decreased oxygen levelsGO:0036293960.017
Rat
regulation of locomotionGO:00400123290.017
negative regulation of growthGO:0045926970.017
regulation of cell migrationGO:00303342890.016
hindbrain developmentGO:003090230.016
cytokine productionGO:00018162470.016
regulation of nucleotide metabolic processGO:00061402690.016
spindle organizationGO:0007051530.016
multicellular organism reproductionGO:0032504420.016
cellular response to endogenous stimulusGO:00714953360.016
interaction with hostGO:0051701420.016
regulation of rna splicingGO:0043484620.016
spermatid differentiationGO:004851540.016
pigment biosynthetic processGO:0046148100.015
mitochondrial rna metabolic processGO:0000959150.015
purine containing compound biosynthetic processGO:0072522880.015
hydrogen peroxide metabolic processGO:0042743200.015
regulation of transmembrane transportGO:00347621390.015
protein import into mitochondrial outer membraneGO:004504040.015
sexual reproductionGO:0019953370.015
regulation of bindingGO:00510981110.015
protein localization to membraneGO:00726571600.014
cell adhesionGO:00071553250.014
muscle structure developmentGO:0061061980.014
regulation of cellular component biogenesisGO:00440872810.014
guanosine containing compound catabolic processGO:19010692390.014
positive regulation of cellular response to oxidative stressGO:190040970.014
erythrocyte differentiationGO:0030218280.014
translationGO:00064121320.014
regulation of meiotic cell cycleGO:005144540.014
cellular ketone metabolic processGO:0042180800.013
regulation of secretionGO:00510461940.013
tissue homeostasisGO:0001894630.013
sperm egg recognitionGO:003503630.013
protein localization to mitochondrionGO:0070585250.013
intrinsic apoptotic signaling pathwayGO:00971931270.013
positive regulation of transportGO:00510503360.013
positive regulation of nucleotide metabolic processGO:00459812300.013
outer mitochondrial membrane organizationGO:000700840.013
cellular modified amino acid metabolic processGO:0006575640.013
regulation of cellular response to stressGO:00801352440.013
regulation of mrna splicing via spliceosomeGO:0048024320.013
signal transduction by phosphorylationGO:00230142970.013
positive regulation of secretionGO:00510471160.013
inflammatory cell apoptotic processGO:000692530.013
locomotory behaviorGO:000762610.012
response to light stimulusGO:0009416870.012
protein autophosphorylationGO:00467771230.012
establishment of ribosome localizationGO:003375340.012
positive regulation of translationGO:0045727350.012
cell morphogenesisGO:00009022960.012
regulation of myeloid cell differentiationGO:0045637810.012
heart processGO:0003015620.012
microtubule organizing center organizationGO:0031023620.012
negative regulation of developmental processGO:00510932470.012
developmental process involved in reproductionGO:0003006660.012
positive regulation of cell migrationGO:00303351720.012
muscle cell differentiationGO:0042692630.012
regulation of cellular amine metabolic processGO:0033238110.012
regulation of protein import into nucleusGO:0042306780.012
heart developmentGO:0007507950.012
negative regulation of transferase activityGO:00513481240.011
spermatid developmentGO:000728640.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
establishment of protein localization to mitochondrionGO:0072655220.011
positive regulation of secretion by cellGO:19035321080.011
ribosome localizationGO:003375040.011
biological adhesionGO:00226103310.011
negative regulation of cellular component organizationGO:00511292350.011
protein targeting to mitochondrionGO:0006626190.011
cellular carbohydrate metabolic processGO:0044262840.011
neural nucleus developmentGO:0048857470.011
neurological system processGO:00508771630.011
regulation of anatomical structure morphogenesisGO:00226032860.011
regulation of cell developmentGO:00602841610.011
cellular response to insulin stimulusGO:0032869410.011
response to oxygen levelsGO:00704821000.011
Rat
eye developmentGO:0001654420.011
viral life cycleGO:00190581320.011
ion homeostasisGO:00508012300.010
response to transition metal nanoparticleGO:1990267290.010
regulation of ribonuclease activityGO:006070030.010
regulation of nuclease activityGO:0032069110.010
sensory perceptionGO:00076001030.010
cellular response to peptideGO:1901653590.010
negative regulation of protein kinase activityGO:0006469980.010
oocyte differentiationGO:000999420.010
response to insulinGO:0032868450.010

HSPD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.472
disease of cellular proliferationDOID:145661740.297
cancerDOID:1621670.177
organ system cancerDOID:00506861640.072
central nervous system diseaseDOID:3311860.063
nervous system diseaseDOID:8634310.063
blood platelet diseaseDOID:2218100.016
hemorrhagic diseaseDOID:2213100.016
hematopoietic system diseaseDOID:741000.016
blood coagulation diseaseDOID:1247210.016
disease of metabolismDOID:00146672950.014
amino acid metabolic disorderDOID:9252500.014
inherited metabolic disorderDOID:6552420.014
hereditary spastic paraplegiaDOID:2476190.001
paraplegiaDOID:607190.001