Homo sapiens

220 known processes

SCRIB

scribbled homolog (Drosophila)

(Aliases: SCRIB1,CRIB1,Vartul,SCRB1)

SCRIB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
limbic system developmentGO:002176130.396
negative regulation of intracellular signal transductionGO:19025321830.203
post embryonic developmentGO:000979120.202
regulation of locomotionGO:00400123290.177
regulation of cellular ketone metabolic processGO:0010565500.136
central nervous system developmentGO:00074171230.127
Mouse
telencephalon developmentGO:0021537170.110
hippocampus developmentGO:002176610.093
maintenance of location in cellGO:0051651620.091
chromatin modificationGO:00165682980.091
cell cell junction organizationGO:0045216690.088
Worm
regulation of cell differentiationGO:00455953930.087
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433620.087
regulation of cellular amino acid metabolic processGO:000652160.085
regulation of establishment of protein localizationGO:00702012420.082
establishment of protein localization to organelleGO:00725941720.082
regulation of cell migrationGO:00303342890.080
astrocyte cell migrationGO:004361510.074
Rat
protein importGO:00170381300.073
protein localization to nucleusGO:00345041360.070
maintenance of protein locationGO:0045185570.070
response to oxygen containing compoundGO:19017003690.069
locomotory behaviorGO:000762610.068
amine metabolic processGO:0009308440.067
cell developmentGO:00484683280.067
cell junction organizationGO:0034330790.066
Worm
release of cytoplasmic sequestered nf kappabGO:000858840.066
negative regulation of hippo signalingGO:003533160.065
cell projection morphogenesisGO:00488581290.064
negative regulation of cellular protein metabolic processGO:00322693530.063
single organism cell adhesionGO:00986021790.060
head developmentGO:00603221080.059
Mouse
single organism nuclear importGO:19025931040.059
hindbrain developmentGO:003090230.059
Mouse
prostate gland developmentGO:003085030.058
vesicle mediated transportGO:00161923710.057
Mouse
regulation of cell motilityGO:20001452990.057
nucleoside triphosphate metabolic processGO:00091414220.057
brain developmentGO:0007420970.057
Mouse
negative regulation of protein transportGO:0051224750.056
cellular response to endogenous stimulusGO:00714953360.056
regulation of protein transportGO:00512232130.056
cellular amino acid metabolic processGO:00065201160.055
taxisGO:00423301570.054
embryonic forelimb morphogenesisGO:003511540.054
covalent chromatin modificationGO:00165692540.052
protein localization to organelleGO:00333652800.050
organelle assemblyGO:00709251760.050
peptidyl lysine acetylationGO:00183941010.049
protein targetingGO:00066051870.048
microtubule cytoskeleton organizationGO:00002261760.048
Zebrafish
regulation of odontogenesisGO:004248140.047
protein targeting to nucleusGO:00447441040.047
maintenance of locationGO:00512351120.047
internal protein amino acid acetylationGO:00064751010.044
protein modification by small protein conjugationGO:00324463420.044
oogenesisGO:004847720.043
protein catabolic processGO:00301633250.043
oocyte developmentGO:004859910.043
internal peptidyl lysine acetylationGO:0018393970.042
cell morphogenesis involved in differentiationGO:00009041440.042
Mouse
chromatin organizationGO:00063253510.041
maintenance of protein location in cellGO:0032507560.041
single organism cellular localizationGO:19025803320.040
Zebrafish
regulation of cellular amine metabolic processGO:0033238110.040
protein import into nucleusGO:00066061040.040
regulation of intracellular protein transportGO:00331571230.040
negative regulation of apoptotic processGO:00430663160.039
protein dephosphorylationGO:0006470810.039
intracellular protein transportGO:00068862700.039
posttranscriptional regulation of gene expressionGO:00106082130.039
determination of adult lifespanGO:000834020.039
nucleocytoplasmic transportGO:00069131760.039
response to lipidGO:00339932060.038
positive regulation of cell migrationGO:00303351720.038
protein depolymerizationGO:0051261300.038
histone acetylationGO:0016573930.038
canonical wnt signaling pathwayGO:00600701160.037
proteolysis involved in cellular protein catabolic processGO:00516032440.037
regulation of cellular component movementGO:00512703340.036
photoreceptor cell differentiationGO:004653020.036
maintenance of cell polarityGO:003001120.035
Worm
cellular ketone metabolic processGO:0042180800.035
cellular amine metabolic processGO:0044106410.035
negative regulation of cell proliferationGO:00082852280.035
regulation of microtubule cytoskeleton organizationGO:0070507610.035
negative regulation of phosphate metabolic processGO:00459362670.035
negative regulation of catalytic activityGO:00430863350.034
oocyte differentiationGO:000999420.034
multicellular organismal agingGO:001025930.034
positive regulation of cellular component movementGO:00512721810.033
nuclear transportGO:00511691790.033
cellular response to organonitrogen compoundGO:00714171240.033
negative regulation of protein kinase b signalingGO:0051898170.033
regulation of cell cycleGO:00517263930.033
intracellular mrna localizationGO:000829810.032
response to growth factorGO:00708482050.032
peptidyl lysine modificationGO:00182051440.032
cytoplasmic transportGO:00164823790.031
mitotic cell cycle processGO:19030472860.031
Zebrafish
positive regulation of cell motilityGO:20001471770.031
immune responseGO:00069553070.031
regulation of lamellipodium morphogenesisGO:200039240.030
positive regulation of protein transportGO:00512221350.029
regulation of cellular response to stressGO:00801352440.029
neural tube formationGO:000184130.029
gene silencing by mirnaGO:0035195230.028
negative regulation of programmed cell deathGO:00430693210.028
small gtpase mediated signal transductionGO:0007264780.028
negative regulation of cell deathGO:00605483450.028
forebrain developmentGO:0030900260.028
regulation of protein kinase activityGO:00458592890.028
response to abiotic stimulusGO:00096283360.028
protein kinase c signalingGO:0070528170.028
intracellular receptor signaling pathwayGO:00305221040.028
gene silencing by rnaGO:0031047260.027
cellular macromolecule catabolic processGO:00442653800.027
ameboidal type cell migrationGO:00016671350.027
positive regulation of locomotionGO:00400171860.027
cellular response to organic cyclic compoundGO:00714071270.027
response to hormoneGO:00097251750.027
reproductive structure developmentGO:0048608550.026
Worm
cellular component morphogenesisGO:00329893140.026
Mouse
regulation of protein targetingGO:1903533910.026
pallium developmentGO:0021543100.026
positive regulation of gtp catabolic processGO:00331261660.026
modification dependent protein catabolic processGO:00199412090.026
cell fate determinationGO:000170930.026
actin filament based processGO:00300292240.025
Worm
regulation of protein import into nucleusGO:0042306780.025
positive regulation of cell developmentGO:0010720920.025
regulation of proteolysisGO:00301622930.025
hematopoietic or lymphoid organ developmentGO:00485341860.025
single organismal cell cell adhesionGO:00163371480.025
regulation of intracellular transportGO:00323861950.025
regulation of cell cycle processGO:00105642660.025
negative regulation of protein metabolic processGO:00512483910.024
eye photoreceptor cell differentiationGO:000175420.024
regulation of glutamine family amino acid metabolic processGO:000082020.024
regulation of immune responseGO:00507762010.024
nitrogen compound transportGO:00717051910.024
myosin filament assemblyGO:003103420.023
modification dependent macromolecule catabolic processGO:00436322120.023
protein acylationGO:00435431380.023
dephosphorylationGO:00163112090.023
cell projection organizationGO:00300302520.023
Mouse
regulation of response to external stimulusGO:00321012220.023
positive regulation of transportGO:00510503360.023
female gamete generationGO:000729220.023
Worm
negative regulation of cell cycleGO:00457861930.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.022
purine containing compound catabolic processGO:00725234110.022
positive regulation of intracellular protein transportGO:0090316760.022
mapk cascadeGO:00001652880.022
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.022
segmentationGO:003528240.022
adherens junction organizationGO:0034332360.022
positive regulation of catabolic processGO:00098963100.022
regulation of protein localizationGO:00328802960.021
regulation of protein complex assemblyGO:00432541470.021
behaviorGO:00076101120.021
regulation of cytoskeleton organizationGO:00514931770.021
Worm
neuromuscular junction developmentGO:000752830.021
response to decreased oxygen levelsGO:0036293960.021
embryonic epithelial tube formationGO:000183840.021
positive regulation of nucleocytoplasmic transportGO:0046824540.021
protein acetylationGO:00064731160.021
regulation of multi organism processGO:00439001570.021
regulation of cell developmentGO:00602841610.021
establishment or maintenance of cytoskeleton polarityGO:003095230.021
regulation of gtp catabolic processGO:00331241800.020
response to nitrogen compoundGO:19016981840.020
protein ubiquitinationGO:00165673140.020
negative regulation of organelle organizationGO:00106391260.020
regulation of cellular component biogenesisGO:00440872810.020
glutamate metabolic processGO:0006536100.020
regulation of bindingGO:00510981110.020
mitotic cell cycleGO:00002783260.020
protein kinase b signalingGO:0043491690.020
response to organic cyclic compoundGO:00140702040.020
neuron developmentGO:00486661130.019
Mouse
response to oxygen levelsGO:00704821000.019
negative regulation of nucleocytoplasmic transportGO:0046823370.019
regulation of oocyte developmentGO:006028110.019
regulation of protein catabolic processGO:00421761550.019
cell projection assemblyGO:00300311260.019
morphogenesis of embryonic epitheliumGO:001633140.019
mitochondrion organizationGO:00070051560.019
positive regulation of protein import into nucleusGO:0042307460.019
immune system developmentGO:00025201950.019
nervous system developmentGO:00073992930.019
nuclear importGO:00511701060.019
regulation of mitotic cell cycleGO:00073461890.018
monocarboxylic acid metabolic processGO:00327871850.018
embryonic hindlimb morphogenesisGO:003511620.018
cellular response to oxidative stressGO:0034599850.018
nucleoside phosphate biosynthetic processGO:19012931090.018
negative regulation of kinase activityGO:00336731060.018
endocytosisGO:00068971590.018
Mouse
regulation of protein serine threonine kinase activityGO:00719001790.018
striated muscle myosin thick filament assemblyGO:007168820.018
negative regulation of intracellular transportGO:0032387600.018
wnt signaling pathwayGO:00160551560.018
carbohydrate derivative biosynthetic processGO:19011372070.018
growthGO:00400072020.018
negative regulation of cytoplasmic transportGO:1903650460.017
regulation of microtubule based processGO:0032886740.017
positive regulation of cytoplasmic transportGO:1903651820.017
regulation of wnt signaling pathwayGO:00301111230.017
cell activationGO:00017752130.017
cellular component assembly involved in morphogenesisGO:0010927730.017
negative regulation of phosphorus metabolic processGO:00105632670.017
positive regulation of cellular component organizationGO:00511303760.017
organophosphate biosynthetic processGO:00904071630.017
glial cell migrationGO:000834740.017
Rat
response to alcoholGO:0097305640.017
system processGO:00030083490.017
negative regulation of intracellular protein transportGO:0090317420.017
positive regulation of protein localization to nucleusGO:1900182480.017
regulation of neuroblast proliferationGO:190269230.017
regulation of endopeptidase activityGO:00525481700.016
lipid metabolic processGO:00066293810.016
apoptotic signaling pathwayGO:00971902680.016
cellular protein catabolic processGO:00442572610.016
reproductive system developmentGO:0061458560.016
Worm
regulation of neurogenesisGO:0050767820.016
development of primary sexual characteristicsGO:0045137350.016
Worm
positive regulation of cell differentiationGO:00455972110.016
positive regulation of cellular component biogenesisGO:00440891580.016
cellular response to abiotic stimulusGO:00712141170.016
spermatid developmentGO:000728640.016
regulation of cytoplasmic transportGO:19036491490.016
translationGO:00064121320.015
regulation of cell maturationGO:190342930.015
dna conformation changeGO:00711031130.015
histone h4 acetylationGO:0043967470.015
response to molecule of bacterial originGO:0002237820.015
histone modificationGO:00165702510.015
embryo developmentGO:00097901230.015
cellular protein complex disassemblyGO:0043624360.015
epidermis morphogenesisGO:004873030.015
rna processingGO:00063962550.015
chromosome segregationGO:00070591140.015
negative regulation of phosphorylationGO:00423261740.015
mitotic nuclear divisionGO:00070671190.015
regulation of histone modificationGO:0031056470.015
mrna metabolic processGO:00160711750.015
nucleotide biosynthetic processGO:00091651090.015
biological adhesionGO:00226103310.015
cellular response to nitrogen compoundGO:19016991440.015
metencephalon developmentGO:002203720.015
Mouse
positive regulation of gtpase activityGO:00435471660.015
cell morphogenesisGO:00009022960.014
Mouse
canonical wnt signaling pathway involved in heart developmentGO:006131630.014
nucleic acid phosphodiester bond hydrolysisGO:00903051020.014
regulation of neural precursor cell proliferationGO:200017740.014
cellular response to oxygen levelsGO:0071453550.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
regulation of anatomical structure morphogenesisGO:00226032860.014
protein deubiquitinationGO:0016579790.014
blastoderm segmentationGO:000735020.014
spermatid differentiationGO:004851540.014
neurogenesisGO:00220081690.014
Zebrafish Mouse Rat
generation of neuronsGO:00486991520.014
Zebrafish Mouse
cellular response to hypoxiaGO:0071456510.014
trachea developmentGO:006043810.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
neuron projection developmentGO:00311751060.014
response to radiationGO:00093141510.014
tripartite regional subdivisionGO:000735120.014
single organism reproductive processGO:0044702980.014
Worm
signal transduction by phosphorylationGO:00230142970.014
positive regulation of programmed cell deathGO:00430682490.014
anterior posterior axis specificationGO:000994820.014
regulation of protein kinase b signalingGO:0051896610.014
autonomic nervous system developmentGO:004848310.013
negative regulation of wnt signaling pathwayGO:0030178690.013
muscle cell cellular homeostasisGO:004671630.013
primary neural tube formationGO:001402030.013
regulation of gene expression epigeneticGO:0040029730.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regionalizationGO:0003002290.013
tube closureGO:006060630.013
carbohydrate metabolic processGO:00059752070.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
microtubule organizing center organizationGO:0031023620.013
protein oligomerizationGO:00512591730.013
regulation of peptidase activityGO:00525471800.013
purine nucleotide catabolic processGO:00061954050.013
negative regulation of protein localization to nucleusGO:1900181340.013
purine ribonucleoside triphosphate catabolic processGO:00092073910.013
positive regulation of cellular amino acid metabolic processGO:004576430.013
guanosine containing compound metabolic processGO:19010682440.013
meiotic chromosome segregationGO:004513240.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of ras gtpase activityGO:00323181280.013
microtubule based processGO:00070172100.013
Zebrafish
motor neuron axon guidanceGO:000804520.013
thymus developmentGO:004853830.013
i kappab kinase nf kappab signalingGO:00072491660.013
neuroblast proliferationGO:000740540.013
positive regulation of protein catabolic processGO:0045732750.012
cytoplasmic sequestering of proteinGO:0051220120.012
endodermal cell fate commitmentGO:000171140.012
meiosis iGO:000712740.012
cellular response to dna damage stimulusGO:00069743790.012
positive regulation of cell proliferationGO:00082843010.012
regulation of gene silencing by rnaGO:006096660.012
organonitrogen compound biosynthetic processGO:19015662000.012
reproductionGO:0000003630.012
Worm
reproductive processGO:00224141060.012
Worm
rhythmic processGO:0048511310.012
glutamine family amino acid metabolic processGO:0009064170.012
negative regulation of mitotic cell cycleGO:00459301020.012
regulation of transferase activityGO:00513383550.012
forelimb morphogenesisGO:003513640.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.012
circadian rhythmGO:0007623210.012
regulation of mapk cascadeGO:00434082620.012
erbb signaling pathwayGO:0038127440.012
skeletal system developmentGO:0001501790.012
defense responseGO:00069523150.012
regulation of microtubule polymerization or depolymerizationGO:0031110270.012
anterior posterior axis specification embryoGO:000859520.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
pharynx developmentGO:006046510.012
Worm
ribonucleoside triphosphate catabolic processGO:00092033910.012
positive regulation of transcription factor import into nucleusGO:0042993250.012
purine ribonucleoside metabolic processGO:00461284370.012
positive regulation of cell adhesionGO:0045785840.012
myosin filament organizationGO:003103320.012
negative regulation of cellular component organizationGO:00511292350.012
regulation of rho gtpase activityGO:0032319660.012
positive regulation of intracellular transportGO:00323881040.012
positive regulation of cellular amine metabolic processGO:003324070.012
organelle fissionGO:00482851490.012
ubiquitin dependent protein catabolic processGO:00065112060.011
regulation of response to woundingGO:19030341010.011
regulation of protein localization to nucleusGO:1900180850.011
protein modification by small protein removalGO:0070646920.011
regulation of protein kinase c signalingGO:009003680.011
negative regulation of hydrolase activityGO:00513461820.011
nuclear divisionGO:00002801280.011
negative regulation of developmental processGO:00510932470.011
endodermal cell fate specificationGO:000171440.011
ribonucleotide catabolic processGO:00092614050.011
reciprocal dna recombinationGO:003582540.011
positive regulation of hydrolase activityGO:00513453310.011
protein localization to adherens junctionGO:007189620.011
regulation of chromosome organizationGO:00330441030.011
cellular response to hormone stimulusGO:00328701250.011
startle responseGO:000196430.011
protein localization to membraneGO:00726571600.011
negative regulation of multicellular organismal processGO:00512413170.011
multicellular organismal reproductive processGO:0048609400.011
Worm
lamellipodium organizationGO:0097581300.011
axonogenesisGO:0007409310.011
positive regulation of mapk cascadeGO:00434101900.011
response to hypoxiaGO:0001666960.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of protein complex assemblyGO:0031334860.011
response to starvationGO:0042594590.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
epithelial cell differentiationGO:00308551410.011
Mouse
negative regulation of protein phosphorylationGO:00019331400.010
peptidyl tyrosine phosphorylationGO:00181081700.010
neurotransmitter secretionGO:000726940.010
Mouse
cellular response to growth factor stimulusGO:00713631970.010
cell cycle arrestGO:0007050710.010
alpha amino acid metabolic processGO:1901605720.010
negative regulation of transportGO:00510511760.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
sensory perceptionGO:00076001030.010
regulation of microtubule polymerizationGO:0031113120.010
positive regulation of immune system processGO:00026842830.010
nucleoside phosphate catabolic processGO:19012924120.010
glycosyl compound catabolic processGO:19016584130.010
regulation of gtpase activityGO:00430871800.010
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.010
Worm
cellular macromolecular complex assemblyGO:00346223240.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
cell morphogenesis involved in neuron differentiationGO:0048667440.010
Mouse
single organism carbohydrate metabolic processGO:00447231930.010
gtp metabolic processGO:00460392390.010
tissue migrationGO:00901301190.010
cellular response to decreased oxygen levelsGO:0036294510.010

SCRIB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
liver diseaseDOID:40970.158
gastrointestinal system diseaseDOID:77360.158
hepatobiliary diseaseDOID:311870.158
musculoskeletal system diseaseDOID:172230.042
cancerDOID:1621670.035
gastrointestinal system cancerDOID:3119520.035
disease of cellular proliferationDOID:145661740.035
organ system cancerDOID:00506861640.035
muscular diseaseDOID:00800001140.021
disease of metabolismDOID:00146672950.018
muscle tissue diseaseDOID:661130.014
myopathyDOID:4231040.014
central nervous system diseaseDOID:3311860.013
nervous system diseaseDOID:8634310.013
connective tissue diseaseDOID:651090.013
neurodegenerative diseaseDOID:12891020.012
bone diseaseDOID:0080001880.011
large intestine cancerDOID:5672290.010
intestinal cancerDOID:10155290.010
colorectal cancerDOID:9256290.010