Homo sapiens

0 known processes

SETDB1

SET domain, bifurcated 1

(Aliases: KMT1E,KG1T,ESET,H3-K9-HMTase4,KIAA0067)

SETDB1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein catabolic processGO:00301633250.706
negative regulation of cell differentiationGO:00455961710.684
positive regulation of apoptotic processGO:00430652460.682
negative regulation of developmental processGO:00510932470.615
post embryonic developmentGO:000979120.548
Fly
cellular macromolecule catabolic processGO:00442653800.542
dna hypermethylationGO:004402610.520
Fly
methylationGO:00322591060.502
Human Mouse Fly
cellular response to endogenous stimulusGO:00714953360.501
regulation of cell growthGO:00015581350.477
regulation of response to external stimulusGO:00321012220.460
negative regulation of protein metabolic processGO:00512483910.459
protein modification by small protein conjugationGO:00324463420.422
response to oxygen containing compoundGO:19017003690.414
positive regulation of cell deathGO:00109422630.391
positive regulation of cell proliferationGO:00082843010.388
regulation of kinase activityGO:00435493140.379
canonical wnt signaling pathwayGO:00600701160.368
pharynx developmentGO:006046510.350
developmental growthGO:0048589480.317
Mouse
regulation of protein modification by small protein conjugation or removalGO:19033201070.314
negative regulation of cellular protein metabolic processGO:00322693530.297
oogenesisGO:004847720.286
Fly
negative regulation of multicellular organismal processGO:00512413170.282
determination of adult lifespanGO:000834020.277
mitotic cell cycleGO:00002783260.262
Human
negative regulation of protein modification processGO:00314002000.223
ubiquitin dependent protein catabolic processGO:00065112060.221
cellular response to nitrogen compoundGO:19016991440.210
negative regulation of axonogenesisGO:005077140.204
negative regulation of phosphorylationGO:00423261740.191
regulation of growthGO:00400081650.188
positive regulation of proteolysisGO:00458621420.170
response to nitrogen compoundGO:19016981840.170
regulation of endopeptidase activityGO:00525481700.167
regulation of cell developmentGO:00602841610.167
protein modification by small protein removalGO:0070646920.159
cellular response to organic cyclic compoundGO:00714071270.157
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.154
Mouse
wnt signaling pathwayGO:00160551560.149
transmission of nerve impulseGO:0019226110.146
regulation of cellular amino acid metabolic processGO:000652160.142
protein ubiquitinationGO:00165673140.140
positive regulation of chromosome organizationGO:2001252410.138
cellular response to organonitrogen compoundGO:00714171240.136
response to radiationGO:00093141510.133
covalent chromatin modificationGO:00165692540.131
Human Mouse Fly
nuclear migrationGO:000709710.129
dna packagingGO:0006323770.129
purine containing compound catabolic processGO:00725234110.123
multicellular organismal agingGO:001025930.121
metencephalon developmentGO:002203720.117
regulation of cell cycleGO:00517263930.114
endothelial cell proliferationGO:0001935650.109
phospholipid catabolic processGO:0009395120.109
epithelial cell migrationGO:00106311190.098
female gamete generationGO:000729220.094
Fly
positive regulation of transferase activityGO:00513472270.094
collateral sproutingGO:004866820.091
positive regulation of protein kinase activityGO:00458601900.088
regulation of protein ubiquitinationGO:0031396950.088
regulation of cysteine type endopeptidase activityGO:20001161270.087
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.086
cellular response to oxygen containing compoundGO:19017012760.082
cellular protein catabolic processGO:00442572610.082
cellular amino acid metabolic processGO:00065201160.080
regulation of cell morphogenesis involved in differentiationGO:0010769830.078
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.077
regulation of innate immune responseGO:0045088970.075
regulation of transferase activityGO:00513383550.075
central nervous system developmentGO:00074171230.074
histone modificationGO:00165702510.073
Human Mouse Fly
growthGO:00400072020.072
Mouse
stress activated protein kinase signaling cascadeGO:0031098940.070
cellular response to growth factor stimulusGO:00713631970.070
negative regulation of neurogenesisGO:0050768260.069
taxisGO:00423301570.069
cellular response to hypoxiaGO:0071456510.069
hindbrain developmentGO:003090230.067
activation of cysteine type endopeptidase activityGO:0097202570.066
chromatin modificationGO:00165682980.065
Human Mouse Fly
translationGO:00064121320.064
cellular response to oxidative stressGO:0034599850.064
proteolysis involved in cellular protein catabolic processGO:00516032440.062
negative regulation of cell projection organizationGO:0031345220.062
positive regulation of cellular amine metabolic processGO:003324070.062
positive regulation of cell differentiationGO:00455972110.060
modification dependent protein catabolic processGO:00199412090.059
cellular response to decreased oxygen levelsGO:0036294510.059
regulation of cell divisionGO:00513021160.059
cell divisionGO:00513011680.058
Fly
signal transduction by p53 class mediatorGO:0072331720.057
regulation of translationGO:0006417890.057
innate immune responseGO:00450871780.056
positive regulation of kinase activityGO:00336742040.055
regulation of protein catabolic processGO:00421761550.055
membrane organizationGO:00610242920.055
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.054
macromolecule methylationGO:0043414970.053
Human Mouse Fly
positive regulation of cellular catabolic processGO:00313312840.052
intrinsic apoptotic signaling pathwayGO:00971931270.052
lipid modificationGO:0030258840.051
reproductive system developmentGO:0061458560.050
positive regulation of macroautophagyGO:0016239120.049
amine metabolic processGO:0009308440.048
defense response to other organismGO:00985421290.048
modification dependent macromolecule catabolic processGO:00436322120.048
negative regulation of programmed cell deathGO:00430693210.047
response to endoplasmic reticulum stressGO:0034976490.047
negative regulation of growthGO:0045926970.047
regulation of defense responseGO:00313471540.046
positive regulation of protein sumoylationGO:003323570.046
cellular response to peptide hormone stimulusGO:0071375560.046
positive regulation of organelle organizationGO:00106381950.045
epithelium migrationGO:00901321190.045
negative regulation of cell cycleGO:00457861930.044
neuronal action potentialGO:001922890.044
regulation of cellular ketone metabolic processGO:0010565500.044
regulation of cell cycle processGO:00105642660.044
positive regulation of cellular protein catabolic processGO:1903364370.043
dna methylation or demethylationGO:0044728190.042
Fly
regulation of epithelial cell migrationGO:0010632930.042
positive regulation of catabolic processGO:00098963100.042
negative regulation of protein ubiquitinationGO:0031397350.042
negative regulation of neuron differentiationGO:0045665210.042
regulation of cellular amine metabolic processGO:0033238110.042
regulation of glial cell proliferationGO:006025140.041
negative regulation of phosphate metabolic processGO:00459362670.041
nucleosome assemblyGO:0006334500.041
positive regulation of chromatin modificationGO:1903310300.040
cell growthGO:00160491600.040
system processGO:00030083490.040
response to vitaminGO:0033273130.040
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.040
stress activated mapk cascadeGO:0051403930.040
regulation of cell motilityGO:20001452990.039
regulation of cellular response to stressGO:00801352440.039
regulation of neuroblast proliferationGO:190269230.039
intracellular receptor signaling pathwayGO:00305221040.038
cell cell junction organizationGO:0045216690.038
response to abiotic stimulusGO:00096283360.038
endocytosisGO:00068971590.038
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.037
regulation of mapk cascadeGO:00434082620.037
response to epidermal growth factorGO:0070849140.037
regulation of response to nutrient levelsGO:0032107220.037
neurofilament bundle assemblyGO:003369320.037
regulation of cell projection organizationGO:00313441070.037
axon developmentGO:0061564340.037
cell developmentGO:00484683280.037
Fly
negative regulation of protein phosphorylationGO:00019331400.036
regulation of wnt signaling pathwayGO:00301111230.036
tissue migrationGO:00901301190.035
nucleus localizationGO:005164710.035
response to organic cyclic compoundGO:00140702040.034
positive regulation of proteasomal protein catabolic processGO:1901800350.034
g2 m transition of mitotic cell cycleGO:0000086410.034
response to extracellular stimulusGO:0009991850.034
response to hormoneGO:00097251750.034
protein sumoylationGO:0016925250.033
regulation of cell differentiationGO:00455953930.033
embryo developmentGO:00097901230.033
Mouse
purine nucleoside catabolic processGO:00061523980.032
regulation of map kinase activityGO:00434051080.032
cell adhesionGO:00071553250.032
negative regulation of cell proliferationGO:00082852280.032
apoptotic signaling pathwayGO:00971902680.032
regulation of axonogenesisGO:0050770160.032
regulation of gene silencingGO:0060968240.032
Fly
regulation of neuron differentiationGO:0045664700.032
regulation of dna repairGO:0006282470.032
regulation of cellular component movementGO:00512703340.031
establishment of nucleus localizationGO:004002310.031
negative regulation of t cell apoptotic processGO:007023340.031
regulation of gtp catabolic processGO:00331241800.030
positive regulation of programmed cell deathGO:00430682490.030
cell cycle phase transitionGO:00447701730.030
single organism cellular localizationGO:19025803320.030
response to other organismGO:00517072610.030
negative regulation of cellular component movementGO:00512711060.030
positive regulation of protein catabolic processGO:0045732750.030
regulation of endothelial cell migrationGO:0010594670.029
mitotic cell cycle phase transitionGO:00447721620.029
regulation of protein localizationGO:00328802960.029
regulation of epithelial cell proliferationGO:00506781130.029
negative regulation of cellular component organizationGO:00511292350.029
negative regulation of cell growthGO:0030308830.029
smooth muscle cell migrationGO:0014909180.028
caveolin mediated endocytosisGO:007258440.028
positive regulation of developmental processGO:00510943140.027
multicellular organismal signalingGO:0035637340.027
regulation of autophagyGO:0010506520.027
glucan metabolic processGO:0044042220.027
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.027
positive regulation of protein phosphorylationGO:00019343130.027
endothelial cell migrationGO:0043542860.026
single organism carbohydrate metabolic processGO:00447231930.026
regulation of dna methylationGO:004403020.026
Fly
regulation of response to biotic stimulusGO:0002831550.025
internal peptidyl lysine acetylationGO:0018393970.025
cellular response to hormone stimulusGO:00328701250.025
negative regulation of transportGO:00510511760.025
cellular senescenceGO:0090398340.025
vesicle mediated transportGO:00161923710.025
positive regulation of endothelial cell migrationGO:0010595390.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
regulation of immune responseGO:00507762010.024
epithelial cell proliferationGO:00506731280.024
cellular polysaccharide metabolic processGO:0044264270.023
dna modificationGO:0006304270.023
Fly
immune responseGO:00069553070.023
positive regulation of mapk cascadeGO:00434101900.023
organic acid catabolic processGO:0016054710.023
regulation of generation of precursor metabolites and energyGO:0043467270.022
negative regulation of transferase activityGO:00513481240.022
regulation of dna metabolic processGO:00510521530.022
Fly
positive regulation of cell cycleGO:00457871400.022
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.022
regulation of apoptotic signaling pathwayGO:20012331750.021
rna catabolic processGO:0006401710.021
glandular epithelial cell differentiationGO:000206760.021
sex differentiationGO:0007548450.021
cellular ketone metabolic processGO:0042180800.021
regulation of anatomical structure morphogenesisGO:00226032860.021
regulation of protein serine threonine kinase activityGO:00719001790.021
regulation of collateral sproutingGO:004867020.021
cellular response to starvationGO:0009267580.021
dna repairGO:00062811980.021
oxidation reduction processGO:00551143960.021
regulation of response to dna damage stimulusGO:2001020940.021
cellular macromolecular complex assemblyGO:00346223240.021
response to nutrientGO:0007584200.021
endomembrane system organizationGO:00102561960.020
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.020
regulation of neuron projection developmentGO:0010975570.020
regulation of proteolysisGO:00301622930.020
regulation of glucosylceramide catabolic processGO:200075210.020
protein acetylationGO:00064731160.020
negative regulation of nervous system developmentGO:0051961280.020
developmental process involved in reproductionGO:0003006660.020
Fly
regulation of mitotic cell cycleGO:00073461890.020
histone h3 k9 modificationGO:0061647110.020
Human Mouse Fly
protein alkylationGO:0008213740.020
Human Mouse Fly
dna replicationGO:00062601160.019
posttranscriptional regulation of gene expressionGO:00106082130.019
cristae formationGO:004240730.019
single organism membrane organizationGO:00448022680.019
response to reactive oxygen speciesGO:0000302610.019
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.019
astrocyte developmentGO:001400210.019
negative regulation of neuron projection developmentGO:0010977150.019
cell part morphogenesisGO:00329901370.019
regulation of axon guidanceGO:190266730.019
neuromuscular junction developmentGO:000752830.019
regulation of mitosisGO:0007088630.019
phagocytosisGO:0006909420.019
defense responseGO:00069523150.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.019
proteasomal protein catabolic processGO:00104981760.018
regulation of protein kinase activityGO:00458592890.018
apoptotic cell clearanceGO:0043277120.018
regulation of histone modificationGO:0031056470.018
striated muscle cell apoptotic processGO:001065830.018
sulfur compound metabolic processGO:00067901010.018
positive regulation of vasoconstrictionGO:004590730.018
glycogen biosynthetic processGO:0005978160.018
positive regulation of response to extracellular stimulusGO:0032106140.017
nucleoside triphosphate catabolic processGO:00091433940.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
negative regulation of receptor mediated endocytosisGO:004826160.017
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.017
trna processingGO:0008033230.017
cytoplasmic transportGO:00164823790.017
nerve developmentGO:002167540.016
histone lysine methylationGO:0034968500.016
Human Mouse Fly
brain developmentGO:0007420970.016
reproductive processGO:00224141060.016
Fly
regulation of histone methylationGO:0031060160.016
signal transduction by phosphorylationGO:00230142970.016
cell type specific apoptotic processGO:00972851250.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.016
regenerationGO:003109940.016
positive regulation of immune system processGO:00026842830.016
positive regulation of innate immune responseGO:0045089790.015
neurogenesisGO:00220081690.015
negative regulation of mitotic cell cycleGO:00459301020.015
regulation of mitotic cell cycle phase transitionGO:19019901180.015
glycogen metabolic processGO:0005977220.015
neuron projection developmentGO:00311751060.015
establishment of planar polarityGO:000173630.015
head developmentGO:00603221080.015
negative regulation of cell deathGO:00605483450.015
stem cell divisionGO:001714520.015
Fly
positive regulation of epithelial cell proliferationGO:0050679650.015
response to nutrient levelsGO:0031667810.015
nucleocytoplasmic transportGO:00069131760.014
response to peptideGO:1901652650.014
signal transduction in response to dna damageGO:0042770570.014
lymphocyte homeostasisGO:000226040.014
cellular response to peptideGO:1901653590.014
single organism reproductive processGO:0044702980.014
Fly
response to transforming growth factor betaGO:0071559940.014
regulation of nucleotide metabolic processGO:00061402690.014
negative regulation of kinase activityGO:00336731060.014
response to inorganic substanceGO:00100351270.014
ameboidal type cell migrationGO:00016671350.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
regulation of peptidase activityGO:00525471800.014
cell cycle g2 m phase transitionGO:0044839430.014
regulation of neurogenesisGO:0050767820.013
cell cycle g1 s phase transitionGO:0044843800.013
response to organonitrogen compoundGO:00102431560.013
negative regulation of apoptotic processGO:00430663160.013
reactive oxygen species biosynthetic processGO:190340940.013
positive regulation of autophagyGO:0010508240.013
regulation of leukocyte apoptotic processGO:2000106250.013
negative regulation of response to external stimulusGO:0032102830.013
autophagyGO:0006914880.013
regulation of cellular protein catabolic processGO:1903362960.013
negative regulation of intracellular signal transductionGO:19025321830.013
positive regulation of response to dna damage stimulusGO:2001022430.012
regulation of female gonad developmentGO:200019410.012
camera type eye developmentGO:0043010250.012
cell junction organizationGO:0034330790.012
establishment of protein localization to organelleGO:00725941720.012
cellular response to nutrient levelsGO:0031669690.012
methylation dependent chromatin silencingGO:000634630.012
cellular response to insulin stimulusGO:0032869410.012
negative regulation of wnt signaling pathwayGO:0030178690.012
positive regulation of superoxide anion generationGO:003293040.012
response to cytokineGO:00340972320.012
regulation of endothelial cell proliferationGO:0001936560.012
cellular amine metabolic processGO:0044106410.012
monocarboxylic acid catabolic processGO:0072329370.012
g1 s transition of mitotic cell cycleGO:0000082780.012
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.012
transforming growth factor beta receptor signaling pathwayGO:0007179760.012
protein dephosphorylationGO:0006470810.012
adherens junction assemblyGO:0034333340.012
dna alkylationGO:000630570.012
Fly
peptidyl lysine acetylationGO:00183941010.011
response to starvationGO:0042594590.011
protein deubiquitinationGO:0016579790.011
biological adhesionGO:00226103310.011
atp metabolic processGO:00460341760.011
protein processingGO:00164852260.011
regulation of chemotaxisGO:0050920740.011
glucan biosynthetic processGO:0009250160.011
nucleotide catabolic processGO:00091664080.011
mitochondrion organizationGO:00070051560.011
regulation of behaviorGO:0050795820.011
carbohydrate homeostasisGO:0033500310.011
positive regulation of glial cell proliferationGO:006025220.011
negative regulation of protein kinase activityGO:0006469980.011
protein maturationGO:00516042330.011
regulation of cell sizeGO:0008361190.011
regulation of protein processingGO:00706131500.011
rna processingGO:00063962550.011
regulation of glycogen metabolic processGO:0070873150.011
maintenance of locationGO:00512351120.011
cellular response to oxygen levelsGO:0071453550.011
spinal cord developmentGO:002151040.011
negative regulation of cellular catabolic processGO:0031330830.011
response to alcoholGO:0097305640.011
ribonucleotide biosynthetic processGO:0009260810.011
response to decreased oxygen levelsGO:0036293960.011
rna modificationGO:0009451270.011
neuron projection morphogenesisGO:0048812500.011
response to hypoxiaGO:0001666960.011
regulation of locomotionGO:00400123290.011
negative regulation of collateral sproutingGO:004867110.011
negative regulation of cell developmentGO:0010721480.011
thymus developmentGO:004853830.010
embryonic hindlimb morphogenesisGO:003511620.010
positive regulation of alpha beta t cell differentiationGO:004663840.010
positive regulation of t cell activationGO:0050870540.010
negative regulation of immune system processGO:00026831360.010
regulation of myelinationGO:003164110.010
response to ionizing radiationGO:0010212650.010
cellular response to monoamine stimulusGO:007186870.010
regulation of macroautophagyGO:0016241190.010
response to oxidative stressGO:00069791210.010
response to axon injuryGO:004867810.010
regulation of glucose transportGO:0010827230.010
t cell homeostasisGO:004302930.010
jnk cascadeGO:0007254800.010

SETDB1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
disease of cellular proliferationDOID:145661740.020
cardiovascular system diseaseDOID:12871060.018
heart diseaseDOID:114680.018
heart septal defectDOID:1681140.018
congenital heart diseaseDOID:1682160.018
physical disorderDOID:0080015410.011
gastrointestinal system cancerDOID:3119520.011