Homo sapiens

50 known processes

CTSB

cathepsin B

(Aliases: APPS,CPSB)

CTSB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein maturationGO:00516042330.917
negative regulation of peptidase activityGO:0010466910.908
protein processingGO:00164852260.857
regulation of peptidase activityGO:00525471800.853
regulation of protein processingGO:00706131500.804
peptide cross linkingGO:0018149120.773
negative regulation of proteolysisGO:00458611320.772
epithelium developmentGO:00604292270.712
regulation of blood vessel remodelingGO:006031220.675
negative regulation of endopeptidase activityGO:0010951840.667
negative regulation of cellular protein metabolic processGO:00322693530.659
epithelial cell differentiationGO:00308551410.653
regulation of mapk cascadeGO:00434082620.647
negative regulation of protein maturationGO:19033181420.569
signal transduction by phosphorylationGO:00230142970.566
vasculature developmentGO:00019441810.546
negative regulation of catalytic activityGO:00430863350.541
negative regulation of hydrolase activityGO:00513461820.456
secretion by cellGO:00329402260.455
negative regulation of elastin catabolic processGO:006031110.421
g protein coupled receptor signaling pathwayGO:00071862070.417
negative regulation of protein metabolic processGO:00512483910.398
negative regulation of multicellular organismal processGO:00512413170.391
epidermal cell differentiationGO:0009913450.340
regulation of cellular ketone metabolic processGO:0010565500.327
regulation of endopeptidase activityGO:00525481700.317
cellular response to endogenous stimulusGO:00714953360.307
keratinocyte differentiationGO:0030216360.278
response to thyroid hormoneGO:009706690.270
circulatory system developmentGO:00723592620.264
blood vessel morphogenesisGO:00485141620.263
extracellular matrix organizationGO:0030198410.261
response to hormoneGO:00097251750.246
negative regulation of protein processingGO:00109551420.237
nervous system developmentGO:00073992930.236
negative regulation of locomotionGO:00400131180.235
protein heterotetramerizationGO:005129030.232
chemical homeostasisGO:00488783060.225
regulation of protein maturationGO:19033171500.213
negative regulation of phospholipase activityGO:001051930.208
gtp metabolic processGO:00460392390.205
system processGO:00030083490.202
defense responseGO:00069523150.181
Worm
response to xenobiotic stimulusGO:0009410300.179
regulation of secretionGO:00510461940.176
mapk cascadeGO:00001652880.176
regulation of vasculature developmentGO:1901342970.169
biological adhesionGO:00226103310.159
cytokine productionGO:00018162470.159
negative regulation of cell motilityGO:20001461040.158
single organismal cell cell adhesionGO:00163371480.151
regulation of proteolysisGO:00301622930.150
negative regulation of multicellular organismal metabolic processGO:004425230.148
skin developmentGO:0043588760.146
regulation of integrin mediated signaling pathwayGO:200104430.146
sterol transportGO:0015918390.145
regulation of gtp catabolic processGO:00331241800.140
regulation of cell adhesionGO:00301551660.138
secretionGO:00469032540.135
regulation of cell migrationGO:00303342890.135
small gtpase mediated signal transductionGO:0007264780.134
regulation of elastin catabolic processGO:006031010.132
immune responseGO:00069553070.132
Worm
anatomical structure formation involved in morphogenesisGO:00486462840.130
anatomical structure homeostasisGO:00602491000.129
metal ion homeostasisGO:00550651690.128
angiogenesisGO:00015251470.126
cell adhesionGO:00071553250.126
positive regulation of programmed cell deathGO:00430682490.125
blood vessel developmentGO:00015681720.121
basement membrane organizationGO:007171130.119
negative regulation of programmed cell deathGO:00430693210.115
membrane raft assemblyGO:000176570.115
guanosine containing compound metabolic processGO:19010682440.114
carbohydrate metabolic processGO:00059752070.111
regulation of rubidium ion transportGO:200068030.111
central nervous system developmentGO:00074171230.111
regulation of angiogenesisGO:0045765920.109
regulation of anatomical structure morphogenesisGO:00226032860.108
vasodilationGO:004231140.108
rho protein signal transductionGO:0007266260.108
cellular response to hormone stimulusGO:00328701250.106
negative regulation of cellular component movementGO:00512711060.105
purine ribonucleoside metabolic processGO:00461284370.105
negative regulation of cell proliferationGO:00082852280.105
regulation of purine nucleotide metabolic processGO:19005422640.104
enzyme linked receptor protein signaling pathwayGO:00071673030.103
sensory perception of chemical stimulusGO:0007606380.102
negative regulation of collagen catabolic processGO:001071110.100
regulation of cellular response to growth factor stimulusGO:0090287760.100
purine nucleoside catabolic processGO:00061523980.098
regulation of cell motilityGO:20001452990.096
ribonucleoside catabolic processGO:00424544060.096
fibroblast proliferationGO:0048144330.095
regulation of gtpase activityGO:00430871800.094
response to woundingGO:00096111680.093
Zebrafish Rat
single organism carbohydrate metabolic processGO:00447231930.093
protein localization to membraneGO:00726571600.093
regulation of purine nucleotide catabolic processGO:00331212050.093
multicellular organismal homeostasisGO:0048871670.092
single organism reproductive processGO:0044702980.091
Mouse Rat
lipid metabolic processGO:00066293810.090
epidermis developmentGO:0008544590.088
regulation of nucleotide catabolic processGO:00308112050.087
sulfur compound metabolic processGO:00067901010.087
regulation of cellular amino acid metabolic processGO:000652160.087
negative regulation of metalloenzyme activityGO:004855310.085
organic hydroxy compound transportGO:0015850630.084
response to growth factorGO:00708482050.084
multicellular organismal macromolecule metabolic processGO:0044259290.084
negative regulation of apoptotic processGO:00430663160.082
nucleoside phosphate catabolic processGO:19012924120.081
positive regulation of protein phosphorylationGO:00019343130.081
ras protein signal transductionGO:0007265730.078
cardiovascular system developmentGO:00723582620.077
gtp catabolic processGO:00061842370.077
regulation of cytokine productionGO:00018172320.076
ribonucleotide catabolic processGO:00092614050.076
positive regulation of angiogenesisGO:0045766510.075
positive regulation of cytoskeleton organizationGO:0051495830.075
purine ribonucleoside triphosphate metabolic processGO:00092054110.074
purine containing compound catabolic processGO:00725234110.074
inflammatory responseGO:0006954790.073
positive regulation of cellular component organizationGO:00511303760.072
negative regulation of cell migrationGO:00303361020.072
gland developmentGO:0048732480.072
reproductive processGO:00224141060.072
Mouse Rat
neurological system processGO:00508771630.069
cellular macromolecule catabolic processGO:00442653800.068
regulation of cellular component movementGO:00512703340.068
ribonucleoside triphosphate catabolic processGO:00092033910.066
i kappab kinase nf kappab signalingGO:00072491660.064
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.064
negative regulation of glycoprotein metabolic processGO:190301980.064
positive regulation of gtpase activityGO:00435471660.064
negative regulation of phosphorylationGO:00423261740.063
cation transmembrane transportGO:00986552380.063
antigen processing and presentationGO:0019882330.063
cell morphogenesisGO:00009022960.063
cellular ketone metabolic processGO:0042180800.062
regulation of hormone levelsGO:00108171250.061
regulation of response to woundingGO:19030341010.061
inorganic ion transmembrane transportGO:00986602310.059
regulation of nucleotide metabolic processGO:00061402690.059
regulation of transferase activityGO:00513383550.058
neuromuscular processGO:0050905150.056
negative regulation of blood vessel remodelingGO:006031310.056
membrane lipid metabolic processGO:0006643530.056
positive regulation of phosphorylationGO:00423273940.055
regulation of apoptotic signaling pathwayGO:20012331750.054
positive regulation of nucleoside metabolic processGO:00459791860.054
negative regulation of cellular catabolic processGO:0031330830.053
response to inorganic substanceGO:00100351270.053
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.052
apoptotic signaling pathwayGO:00971902680.052
negative regulation of serine type peptidase activityGO:190257220.052
positive regulation of epithelial cell proliferationGO:0050679650.050
regulation of rho gtpase activityGO:0032319660.050
nucleoside catabolic processGO:00091644080.050
extracellular matrix disassemblyGO:0022617160.049
positive regulation of cell deathGO:00109422630.049
regulation of cell differentiationGO:00455953930.049
negative regulation of protein serine threonine kinase activityGO:0071901570.049
female gamete generationGO:000729220.049
purine ribonucleoside catabolic processGO:00461303980.049
cellular ion homeostasisGO:00068731680.048
single organism cell adhesionGO:00986021790.047
amino sugar metabolic processGO:0006040150.047
proteolysis involved in cellular protein catabolic processGO:00516032440.047
behaviorGO:00076101120.047
positive regulation of purine nucleotide catabolic processGO:00331231850.047
exocytosisGO:0006887710.046
microtubule based processGO:00070172100.046
negative regulation of protein phosphorylationGO:00019331400.046
nucleoside triphosphate metabolic processGO:00091414220.045
response to metal ionGO:0010038840.045
regulation of blood coagulationGO:0030193420.044
positive regulation of cellular amine metabolic processGO:003324070.044
regulation of bindingGO:00510981110.043
neurogenesisGO:00220081690.042
nucleoside triphosphate catabolic processGO:00091433940.042
negative regulation of phosphate metabolic processGO:00459362670.042
response to nutrient levelsGO:0031667810.042
regulation of vesicle mediated transportGO:00606271300.042
positive regulation of ras gtpase activityGO:00323201170.040
regulation of protein serine threonine kinase activityGO:00719001790.040
purine ribonucleoside triphosphate catabolic processGO:00092073910.039
regulation of kinase activityGO:00435493140.039
ion homeostasisGO:00508012300.039
regulation of defense responseGO:00313471540.038
ribonucleoside triphosphate metabolic processGO:00091994120.038
locomotory behaviorGO:000762610.038
negative regulation of intracellular signal transductionGO:19025321830.038
extracellular structure organizationGO:0043062410.038
cellular response to growth factor stimulusGO:00713631970.036
negative regulation of transferase activityGO:00513481240.036
negative regulation of catabolic processGO:00098951040.036
sensory perceptionGO:00076001030.036
determination of adult lifespanGO:000834020.036
Worm
positive regulation of apoptotic signaling pathwayGO:2001235700.035
nucleotide catabolic processGO:00091664080.035
negative regulation of immune system processGO:00026831360.035
ganglioside metabolic processGO:000157370.035
collagen catabolic processGO:0030574100.035
cellular amino acid metabolic processGO:00065201160.034
negative regulation of camp mediated signalingGO:004395140.034
organophosphate catabolic processGO:00464344300.034
response to reactive oxygen speciesGO:0000302610.034
negative regulation of cell deathGO:00605483450.034
Rat
growthGO:00400072020.033
Zebrafish
cellular amine metabolic processGO:0044106410.033
protein activation cascadeGO:0072376220.033
cellular response to hydrogen peroxideGO:0070301370.033
positive regulation of secretionGO:00510471160.033
calcium ion transportGO:00068161470.033
positive regulation of organelle organizationGO:00106381950.033
sensory perception of bitter tasteGO:0050913280.032
adult locomotory behaviorGO:000834410.032
regulation of vascular endothelial growth factor signaling pathwayGO:190074660.032
endocytosisGO:00068971590.032
Worm
endomembrane system organizationGO:00102561960.032
single organism carbohydrate catabolic processGO:0044724330.031
rubidium ion transportGO:003582640.031
positive regulation of cell motilityGO:20001471770.031
sensory perception of tasteGO:0050909360.030
positive regulation of catabolic processGO:00098963100.030
positive regulation of transportGO:00510503360.030
detection of chemical stimulusGO:0009593550.030
cellular metal ion homeostasisGO:00068751460.030
regulation of response to external stimulusGO:00321012220.030
regulation of systemic arterial blood pressure by hormoneGO:0001990120.030
cellular response to oxygen containing compoundGO:19017012760.030
negative regulation of trophoblast cell migrationGO:190116430.029
plasma membrane organizationGO:00070091150.029
negative regulation of developmental processGO:00510932470.029
response to tumor necrosis factorGO:0034612760.029
regulation of cellular component biogenesisGO:00440872810.029
monovalent inorganic cation transportGO:00156721280.029
positive regulation of gtp catabolic processGO:00331261660.029
regulation of locomotionGO:00400123290.029
glycoprotein metabolic processGO:00091001100.029
cell developmentGO:00484683280.029
regulation of protein secretionGO:0050708860.028
regulation of phospholipase activityGO:0010517260.028
purine ribonucleotide catabolic processGO:00091544040.028
cytoplasmic transportGO:00164823790.028
regulation of fibroblast proliferationGO:0048145320.028
response to other organismGO:00517072610.028
regulation of cellular amine metabolic processGO:0033238110.028
regulation of tube sizeGO:0035150180.028
tissue migrationGO:00901301190.028
neutrophil aggregationGO:007048820.028
regulation of ras protein signal transductionGO:00465781550.028
monocarboxylic acid metabolic processGO:00327871850.028
positive regulation of cell proliferationGO:00082843010.027
xenobiotic metabolic processGO:0006805280.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
matingGO:000761810.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
microtubule cytoskeleton organizationGO:00002261760.026
head developmentGO:00603221080.026
regulation of anatomical structure sizeGO:00900661010.026
cellular response to extracellular stimulusGO:0031668720.026
positive regulation of cellular catabolic processGO:00313312840.026
epithelium migrationGO:00901321190.026
cellular cation homeostasisGO:00300031630.026
response to organonitrogen compoundGO:00102431560.026
Rat
post embryonic developmentGO:000979120.026
Worm
cellular amide metabolic processGO:0043603690.025
positive regulation of striated muscle contractionGO:004598910.025
cellular response to lipidGO:00713961270.025
endothelial cell migrationGO:0043542860.025
amine metabolic processGO:0009308440.025
response to fungusGO:000962040.025
negative regulation of protein transportGO:0051224750.025
cell matrix adhesionGO:0007160850.025
negative regulation of mapk cascadeGO:0043409560.025
cellular response to oxidative stressGO:0034599850.025
regulation of secretion by cellGO:19035301770.024
arachidonic acid metabolic processGO:0019369140.024
cellular response to external stimulusGO:00714961110.024
Rat
regulation of ion transportGO:00432691890.024
negative regulation of cellular component organizationGO:00511292350.024
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.024
hematopoietic or lymphoid organ developmentGO:00485341860.024
regulation of phospholipase a2 activityGO:003242940.024
regulation of inflammatory responseGO:0050727460.023
positive regulation of rho gtpase activityGO:0032321560.023
protein tetramerizationGO:0051262470.023
ion transmembrane transportGO:00342203380.023
response to axon injuryGO:004867810.023
membrane organizationGO:00610242920.022
regulation of collagen catabolic processGO:001071030.022
regulation of angiotensin levels in bloodGO:000200230.022
regulation of rho protein signal transductionGO:0035023790.022
positive regulation of developmental processGO:00510943140.022
regulation of protein kinase activityGO:00458592890.022
positive regulation of apoptotic processGO:00430652460.022
cellular chemical homeostasisGO:00550821800.022
ameboidal type cell migrationGO:00016671350.022
regulation of adrenergic receptor signaling pathwayGO:007187710.022
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.021
leukocyte differentiationGO:0002521980.021
protein catabolic processGO:00301633250.021
single organism membrane organizationGO:00448022680.021
cellular response to reactive oxygen speciesGO:0034614500.021
regulation of establishment of protein localizationGO:00702012420.021
negative regulation of interleukin 8 secretionGO:200048320.021
regulation of epithelial cell proliferationGO:00506781130.021
midbrain developmentGO:0030901450.021
regulation of protein localizationGO:00328802960.021
peptide metabolic processGO:0006518510.021
cell growthGO:00160491600.021
cellular response to decreased oxygen levelsGO:0036294510.020
regulation of cellular response to stressGO:00801352440.020
negative regulation of blood vessel morphogenesisGO:2000181410.020
fibroblast growth factor receptor signaling pathwayGO:0008543260.020
guanosine containing compound catabolic processGO:19010692390.020
epithelial cell proliferationGO:00506731280.020
vascular process in circulatory systemGO:0003018290.020
positive regulation of protein kinase activityGO:00458601900.020
hemopoiesisGO:00300971800.020
dna replicationGO:00062601160.020
negative regulation of protein modification processGO:00314002000.020
response to extracellular stimulusGO:0009991850.020
response to oxidative stressGO:00069791210.020
regulation of small gtpase mediated signal transductionGO:00510561560.020
lipid localizationGO:00108761060.020
osteoclast developmentGO:003603520.020
zymogen activationGO:0031638700.019
monocarboxylic acid biosynthetic processGO:0072330670.019
adaptive immune responseGO:0002250490.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
cytokine secretionGO:0050663640.019
cellular component morphogenesisGO:00329893140.019
negative regulation of oxidative stress induced cell deathGO:1903202170.019
cellular lipid metabolic processGO:00442553030.019
regulation of protein catabolic processGO:00421761550.019
cellular response to glucocorticoid stimulusGO:007138540.019
neuromuscular process controlling balanceGO:005088570.019
regulation of metalloenzyme activityGO:004855230.019
positive regulation of protein serine threonine kinase activityGO:00719021190.019
glycoprotein biosynthetic processGO:0009101910.019
receptor metabolic processGO:0043112810.018
transmembrane transportGO:00550853990.018
metal ion transportGO:00300012720.018
retina development in camera type eyeGO:0060041150.018
multi organism reproductive processGO:0044703540.018
Mouse Rat
tissue homeostasisGO:0001894630.018
agingGO:0007568660.018
Worm
regulation of lipase activityGO:0060191370.018
response to calcium ionGO:0051592460.018
single organism cellular localizationGO:19025803320.018
maintenance of locationGO:00512351120.017
divalent metal ion transportGO:00708381520.017
wnt signaling pathwayGO:00160551560.017
response to drugGO:0042493810.017
cellular divalent inorganic cation homeostasisGO:00725031280.017
negative regulation of phosphorus metabolic processGO:00105632670.017
neutrophil homeostasisGO:000178030.017
response to hydrogen peroxideGO:0042542400.017
glycoprotein catabolic processGO:000651670.016
mitotic cell cycleGO:00002783260.016
cellular lipid catabolic processGO:0044242650.016
cation transportGO:00068123310.016
ganglioside catabolic processGO:000668930.016
negative regulation of cellular amine metabolic processGO:003323930.016
regulation of cytokine secretionGO:0050707570.016
intracellular protein transportGO:00068862700.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
purine nucleotide catabolic processGO:00061954050.016
relaxation of cardiac muscleGO:005511950.016
response to estradiolGO:0032355230.015
negative regulation of protein kinase activityGO:0006469980.015
positive regulation of nucleotide catabolic processGO:00308131850.015
response to organic cyclic compoundGO:00140702040.015
Rat
negative regulation of muscle contractionGO:004593230.015
membrane protein proteolysisGO:0033619380.015
lipid biosynthetic processGO:00086101770.015
leukocyte migrationGO:00509001070.015
response to starvationGO:0042594590.015
developmental process involved in reproductionGO:0003006660.015
Mouse
negative regulation of serine type endopeptidase activityGO:190000420.015
regulation of ras gtpase activityGO:00323181280.015
carboxylic acid biosynthetic processGO:0046394970.015
positive regulation of t cell tolerance inductionGO:000266620.014
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.014
sphingolipid metabolic processGO:0006665380.014
protein secretionGO:0009306980.014
positive regulation of kinase activityGO:00336742040.014
aminoglycan metabolic processGO:0006022390.014
response to radiationGO:00093141510.014
cellular response to organic cyclic compoundGO:00714071270.014
response to estrogenGO:0043627470.014
cellular protein complex assemblyGO:00436231880.014
positive regulation of nucleotide metabolic processGO:00459812300.014
cellular response to thyroid hormone stimulusGO:009706790.014
regulation of system processGO:00440571010.014
regulation of actin filament bundle assemblyGO:0032231360.014
retina homeostasisGO:0001895420.014
response to external biotic stimulusGO:00432072610.014
transition metal ion homeostasisGO:0055076310.014
response to cytokineGO:00340972320.014
Rat
skeletal system developmentGO:0001501790.014
positive regulation of fibroblast proliferationGO:0048146210.014
transition metal ion transportGO:0000041230.014
negative regulation of cell differentiationGO:00455961710.014
positive regulation of cellular component biogenesisGO:00440891580.013
negative regulation of protein activation cascadeGO:200025870.013
protein localization to organelleGO:00333652800.013
protein oligomerizationGO:00512591730.013
cellular response to nutrient levelsGO:0031669690.013
leukocyte mediated immunityGO:0002443590.013
blastocyst developmentGO:000182430.013
cellular response to tumor necrosis factorGO:0071356630.013
negative regulation of angiogenesisGO:0016525390.013
sterol homeostasisGO:0055092280.013
prostate gland developmentGO:003085030.013
cell death in response to oxidative stressGO:0036473290.013
cell projection assemblyGO:00300311260.013
regulation of exocytosisGO:0017157460.013
negative regulation of leukocyte differentiationGO:1902106240.013
reproductive structure developmentGO:0048608550.013
Mouse
glycosaminoglycan metabolic processGO:0030203350.013
response to steroid hormoneGO:0048545800.013
regulation of serine type peptidase activityGO:190257120.013
positive regulation of rac gtpase activityGO:0032855310.013
circulatory system processGO:00030131130.013
tissue morphogenesisGO:0048729960.013
regulation of cell matrix adhesionGO:0001952420.013
negative regulation of vasculature developmentGO:1901343430.013
peptide catabolic processGO:0043171100.013
response to lipidGO:00339932060.013
positive regulation of vesicle fusionGO:003134040.013
substantia nigra developmentGO:0021762450.013
response to oxygen levelsGO:00704821000.013
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.013
oogenesisGO:004847720.013
regulation of serine type endopeptidase activityGO:190000320.013
positive regulation of bindingGO:0051099450.013
negative regulation of cellular response to oxidative stressGO:1900408180.013
myeloid cell differentiationGO:00300991170.013
regulation of growthGO:00400081650.012
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.012
brain developmentGO:0007420970.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.012
positive regulation of cell differentiationGO:00455972110.012
multi multicellular organism processGO:0044706180.012
Mouse
positive regulation of cell developmentGO:0010720920.012
epithelial cell migrationGO:00106311190.012
sequestering of metal ionGO:0051238240.012
oxidation reduction processGO:00551143960.012
intestinal absorptionGO:005089240.012
cellular response to oxygen levelsGO:0071453550.012
regulation of blood vessel sizeGO:0050880180.012
activation of cysteine type endopeptidase activityGO:0097202570.012
response to bacteriumGO:00096171440.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of nucleoside metabolic processGO:00091182090.012
regulation of cell junction assemblyGO:1901888290.011
lipid transportGO:0006869900.011
detection of stimulusGO:0051606850.011
monosaccharide metabolic processGO:0005996740.011
vesicle mediated transportGO:00161923710.011
Worm
negative regulation of cellular response to growth factor stimulusGO:0090288410.011
regulation of lymphocyte activationGO:00512491030.011
antigen processing and presentation of peptide antigenGO:0048002180.011
inorganic cation transmembrane transportGO:00986621940.011

CTSB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.996
disease of metabolismDOID:00146672950.996
lysosomal storage diseaseDOID:3211470.994
lipid storage diseaseDOID:9455280.838
central nervous system diseaseDOID:3311860.550
nervous system diseaseDOID:8634310.550
variable age at onset electroclinical syndromeDOID:005070680.287
brain diseaseDOID:936730.287
epilepsy syndromeDOID:1826410.287
electroclinical syndromeDOID:0050701320.287
progressive myoclonus epilepsyDOID:89180.180
cerebral degenerationDOID:1443160.134
sensory system diseaseDOID:00501552030.054
eye diseaseDOID:56141490.054
eye and adnexa diseaseDOID:14921500.054
retinal diseaseDOID:56791180.052
sphingolipidosisDOID:1927140.040
neuronal ceroid lipofuscinosisDOID:14503110.030
neurodegenerative diseaseDOID:12891020.029
immune system diseaseDOID:29141550.025
acquired metabolic diseaseDOID:0060158580.023
retinal degenerationDOID:8466890.018
leukodystrophyDOID:1057980.013
macular degenerationDOID:4448200.011
degeneration of macula and posterior poleDOID:2007170.011
age related macular degenerationDOID:10871170.011