Homo sapiens

6 known processes

CTSD

cathepsin D

(Aliases: CPSD,MGC2311,CLN10)

CTSD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
elastin catabolic processGO:006030910.779
regulation of elastin catabolic processGO:006031010.743
regulation of blood vessel remodelingGO:006031220.703
vacuole organizationGO:0007033440.484
Mouse
negative regulation of elastin catabolic processGO:006031110.415
negative regulation of collagen catabolic processGO:001071110.378
regulation of lipid metabolic processGO:0019216960.314
negative regulation of blood vessel remodelingGO:006031310.275
ion homeostasisGO:00508012300.252
cellular amine metabolic processGO:0044106410.233
regulation of mapk cascadeGO:00434082620.219
Human
lipid metabolic processGO:00066293810.211
oxidation reduction processGO:00551143960.205
epithelium developmentGO:00604292270.200
Zebrafish
ion transmembrane transportGO:00342203380.174
negative regulation of cell deathGO:00605483450.169
response to abiotic stimulusGO:00096283360.166
locomotory behaviorGO:000762610.164
response to oxygen containing compoundGO:19017003690.131
carbohydrate metabolic processGO:00059752070.131
regulation of oxidative stress induced cell deathGO:1903201240.124
maintenance of locationGO:00512351120.123
circadian behaviorGO:004851220.118
positive regulation of cellular amine metabolic processGO:003324070.117
regulation of protein processingGO:00706131500.116
neuromuscular processGO:0050905150.114
response to oxidative stressGO:00069791210.106
cellular lipid metabolic processGO:00442553030.099
positive regulation of phosphorylationGO:00423273940.098
regulation of cellular ketone metabolic processGO:0010565500.093
neurological system processGO:00508771630.091
regulation of cellular response to stressGO:00801352440.090
cellular response to hydrogen peroxideGO:0070301370.086
regulation of peptidase activityGO:00525471800.085
negative regulation of response to oxidative stressGO:1902883180.084
peptidyl tyrosine phosphorylationGO:00181081700.081
vesicle mediated transportGO:00161923710.079
epithelial cell differentiationGO:00308551410.079
cellular response to reactive oxygen speciesGO:0034614500.078
positive regulation of cellular amino acid metabolic processGO:004576430.076
chemical homeostasisGO:00488783060.075
Human
central nervous system developmentGO:00074171230.075
cellular response to oxidative stressGO:0034599850.075
regulation of transferase activityGO:00513383550.075
eye developmentGO:0001654420.075
Zebrafish
negative regulation of protein metabolic processGO:00512483910.075
signal transduction by phosphorylationGO:00230142970.073
Human
cellular amide metabolic processGO:0043603690.073
Human
regulation of cellular amino acid metabolic processGO:000652160.072
organ morphogenesisGO:00098871470.072
collagen catabolic processGO:0030574100.071
amine metabolic processGO:0009308440.070
transmembrane transportGO:00550853990.070
negative regulation of collagen metabolic processGO:001071330.069
regulation of cellular response to oxidative stressGO:1900407260.066
cell morphogenesisGO:00009022960.066
cellular amino acid metabolic processGO:00065201160.065
negative regulation of cellular protein metabolic processGO:00322693530.065
cation transportGO:00068123310.063
negative regulation of peptidase activityGO:0010466910.059
cation transmembrane transportGO:00986552380.059
response to hormoneGO:00097251750.059
glycerophospholipid metabolic processGO:0006650840.058
cellular ketone metabolic processGO:0042180800.058
negative regulation of multicellular organismal metabolic processGO:004425230.058
mapk cascadeGO:00001652880.057
Human
response to hydrogen peroxideGO:0042542400.057
carbohydrate catabolic processGO:0016052360.056
sensory perception of bitter tasteGO:0050913280.056
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.055
proteolysis involved in cellular protein catabolic processGO:00516032440.055
Yeast
cell developmentGO:00484683280.055
monovalent inorganic cation transportGO:00156721280.054
inorganic ion transmembrane transportGO:00986602310.054
positive regulation of cell proliferationGO:00082843010.054
positive regulation of protein kinase activityGO:00458601900.054
circulatory system developmentGO:00723592620.053
lipid localizationGO:00108761060.053
post embryonic developmentGO:000979120.052
single organism carbohydrate metabolic processGO:00447231930.052
anatomical structure homeostasisGO:00602491000.052
Human
protein processingGO:00164852260.051
Human
hematopoietic or lymphoid organ developmentGO:00485341860.051
negative regulation of cellular response to oxidative stressGO:1900408180.049
response to cytokineGO:00340972320.048
apoptotic signaling pathwayGO:00971902680.048
cellular carbohydrate metabolic processGO:0044262840.047
nervous system developmentGO:00073992930.047
positive regulation of transportGO:00510503360.047
prostate gland developmentGO:003085030.046
negative regulation of apoptotic processGO:00430663160.046
amino acid transportGO:0006865280.046
regulation of secretionGO:00510461940.046
negative regulation of cellular amine metabolic processGO:003323930.046
immune responseGO:00069553070.045
response to reactive oxygen speciesGO:0000302610.045
regulation of collagen catabolic processGO:001071030.045
hexose catabolic processGO:001932070.044
regulation of vesicle mediated transportGO:00606271300.044
regulation of protein maturationGO:19033171500.044
negative regulation of protein maturationGO:19033181420.043
cellular response to oxygen containing compoundGO:19017012760.043
negative regulation of protein processingGO:00109551420.042
response to organic cyclic compoundGO:00140702040.042
negative regulation of cellular component organizationGO:00511292350.041
protein localization to organelleGO:00333652800.040
detection of chemical stimulusGO:0009593550.040
response to axon injuryGO:004867810.040
regulation of cellular amine metabolic processGO:0033238110.039
cell death in response to oxidative stressGO:0036473290.038
alcohol metabolic processGO:00060661140.037
gland developmentGO:0048732480.037
negative regulation of multicellular organismal processGO:00512413170.037
lipid catabolic processGO:0016042840.037
organic hydroxy compound metabolic processGO:19016151470.036
positive regulation of protein phosphorylationGO:00019343130.036
cellular homeostasisGO:00197251960.036
negative regulation of catalytic activityGO:00430863350.035
reproductive processGO:00224141060.035
muscle cell cellular homeostasisGO:004671630.034
cellular macromolecule catabolic processGO:00442653800.033
Yeast
exocytosisGO:0006887710.033
negative regulation of proteolysisGO:00458611320.033
negative regulation of programmed cell deathGO:00430693210.033
system processGO:00030083490.032
Human
monovalent inorganic cation homeostasisGO:0055067370.032
cation homeostasisGO:00550801890.032
positive regulation of mapk cascadeGO:00434101900.032
negative regulation of hydrolase activityGO:00513461820.031
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.031
cell activationGO:00017752130.031
regulation of peptidyl tyrosine phosphorylationGO:00507301080.031
secretion by cellGO:00329402260.030
negative regulation of oxidative stress induced cell deathGO:1903202170.030
regulation of anatomical structure morphogenesisGO:00226032860.030
lipid storageGO:0019915280.030
cytoplasmic transportGO:00164823790.030
negative regulation of intracellular signal transductionGO:19025321830.029
response to decreased oxygen levelsGO:0036293960.029
myeloid cell differentiationGO:00300991170.029
response to oxygen levelsGO:00704821000.028
negative regulation of cellular amino acid metabolic processGO:004576320.028
determination of adult lifespanGO:000834020.028
Worm
cellular component morphogenesisGO:00329893140.028
glycoprotein catabolic processGO:000651670.028
positive regulation of cellular component organizationGO:00511303760.027
membrane lipid metabolic processGO:0006643530.027
hair cell differentiationGO:003531520.027
regulation of kinase activityGO:00435493140.026
rhythmic behaviorGO:000762220.026
positive regulation of protein serine threonine kinase activityGO:00719021190.026
regulation of glycoprotein metabolic processGO:1903018190.026
nuclear divisionGO:00002801280.026
sleepGO:003043120.025
skin developmentGO:0043588760.025
peptide catabolic processGO:0043171100.025
positive regulation of transferase activityGO:00513472270.024
generation of precursor metabolites and energyGO:0006091680.024
amino sugar catabolic processGO:004634830.024
negative regulation of glycoprotein metabolic processGO:190301980.024
chordate embryonic developmentGO:0043009340.024
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.023
multicellular organismal macromolecule metabolic processGO:0044259290.023
response to inorganic substanceGO:00100351270.023
carboxylic acid transportGO:0046942630.023
single organism reproductive processGO:0044702980.023
immune system developmentGO:00025201950.023
response to thyroid hormoneGO:009706690.023
proteasomal protein catabolic processGO:00104981760.023
protein modification by small protein conjugationGO:00324463420.023
posttranscriptional regulation of gene expressionGO:00106082130.023
negative regulation of protein modification processGO:00314002000.022
response to alcoholGO:0097305640.022
regulation of intracellular transportGO:00323861950.022
regulation of cytokine productionGO:00018172320.022
defense responseGO:00069523150.022
Worm
cellular ion homeostasisGO:00068731680.022
peripheral nervous system developmentGO:000742220.022
response to hypoxiaGO:0001666960.022
positive regulation of epithelial cell proliferationGO:0050679650.021
positive regulation of kinase activityGO:00336742040.021
cytokine productionGO:00018162470.021
regulation of erk1 and erk2 cascadeGO:0070372990.021
positive regulation of leukocyte degranulationGO:004330230.021
microtubule based processGO:00070172100.021
regulation of proteolysisGO:00301622930.021
regulation of cell adhesionGO:00301551660.021
regulation of endopeptidase activityGO:00525481700.020
regulation of response to oxidative stressGO:1902882260.020
negative regulation of endopeptidase activityGO:0010951840.020
response to organonitrogen compoundGO:00102431560.020
regulation of cellular phGO:0030641170.020
cellular protein catabolic processGO:00442572610.020
Yeast
cellular cation homeostasisGO:00300031630.020
reactive oxygen species biosynthetic processGO:190340940.020
sensory perceptionGO:00076001030.020
wnt signaling pathwayGO:00160551560.020
response to fungusGO:000962040.020
circadian sleep wake cycle processGO:002241020.019
epidermis developmentGO:0008544590.019
regulation of protein kinase activityGO:00458592890.019
sulfur compound metabolic processGO:00067901010.019
negative regulation of cellular catabolic processGO:0031330830.019
cerebellum developmentGO:002154920.019
female gamete generationGO:000729220.019
cellular protein complex assemblyGO:00436231880.019
dna replicationGO:00062601160.019
response to lipidGO:00339932060.018
reproductive system developmentGO:0061458560.018
blood vessel remodelingGO:000197420.018
growthGO:00400072020.018
regulation of wnt signaling pathwayGO:00301111230.018
small molecule biosynthetic processGO:00442831570.018
head developmentGO:00603221080.018
positive regulation of secretion by cellGO:19035321080.018
developmental process involved in reproductionGO:0003006660.017
carbohydrate derivative biosynthetic processGO:19011372070.017
reactive oxygen species metabolic processGO:0072593750.017
phospholipid metabolic processGO:0006644990.017
cellular chemical homeostasisGO:00550821800.017
positive regulation of immune system processGO:00026842830.017
single organism membrane organizationGO:00448022680.017
Yeast
regulation of cellular component movementGO:00512703340.017
protein stabilizationGO:0050821640.017
multicellular organismal metabolic processGO:0044236340.017
protein ubiquitinationGO:00165673140.016
regenerationGO:003109940.016
urogenital system developmentGO:0001655650.016
Human
protein maturationGO:00516042330.016
Human
thiamine transportGO:001588830.016
regulation of cell motilityGO:20001452990.016
reactive nitrogen species metabolic processGO:200105730.016
multicellular organismal agingGO:001025930.016
Worm
divalent metal ion transportGO:00708381520.016
regulation of establishment of protein localizationGO:00702012420.016
developmental growth involved in morphogenesisGO:0060560230.016
neuromuscular process controlling balanceGO:005088570.016
embryo developmentGO:00097901230.016
neurogenesisGO:00220081690.016
positive regulation of necrotic cell deathGO:001094040.015
hemopoiesisGO:00300971800.015
sensory perception of tasteGO:0050909360.015
lysosome organizationGO:0007040240.015
response to nitrogen compoundGO:19016981840.015
ubiquitin dependent protein catabolic processGO:00065112060.015
positive regulation of endocytosisGO:0045807420.015
reproductive structure developmentGO:0048608550.015
embryonic morphogenesisGO:0048598850.015
metal ion homeostasisGO:00550651690.015
leukocyte mediated immunityGO:0002443590.015
activation of protein kinase activityGO:0032147900.015
negative regulation of transferase activityGO:00513481240.015
positive regulation of secretionGO:00510471160.015
azole transportGO:004511740.015
hydrogen transportGO:0006818230.015
hormone metabolic processGO:0042445610.015
Human
brain developmentGO:0007420970.015
leukocyte activationGO:00453211640.015
respiratory system processGO:000301630.014
negative regulation of protein catabolic processGO:0042177590.014
cellular component disassemblyGO:0022411920.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
regulation of exocytosisGO:0017157460.014
cholesterol metabolic processGO:0008203280.014
tissue regenerationGO:004224630.014
regulation of lymphocyte activationGO:00512491030.014
regulation of growthGO:00400081650.014
bone resorptionGO:004545360.014
regulation of homeostatic processGO:00328441210.014
hindbrain developmentGO:003090230.014
internal peptidyl lysine acetylationGO:0018393970.014
neuromuscular junction developmentGO:000752830.014
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.014
neuromuscular process controlling postureGO:005088420.014
cell type specific apoptotic processGO:00972851250.013
alcohol biosynthetic processGO:0046165520.013
negative regulation of protein phosphorylationGO:00019331400.013
generation of neuronsGO:00486991520.013
steroid metabolic processGO:0008202940.013
response to external biotic stimulusGO:00432072610.013
Zebrafish
antigen processing and presentationGO:0019882330.013
Human
lipid biosynthetic processGO:00086101770.013
peptidyl lysine modificationGO:00182051440.013
calcium ion homeostasisGO:00550741220.013
cellular metal ion homeostasisGO:00068751460.013
regulation of protein catabolic processGO:00421761550.013
regulation of cell cycle processGO:00105642660.013
regulation of bone remodelingGO:004685060.013
negative regulation of phosphorylationGO:00423261740.013
regulation of multicellular organismal metabolic processGO:0044246170.012
protein localization to endoplasmic reticulumGO:0070972190.012
tissue morphogenesisGO:0048729960.012
cell growthGO:00160491600.012
blastocyst developmentGO:000182430.012
organic hydroxy compound transportGO:0015850630.012
epithelial tube branching involved in lung morphogenesisGO:006044140.012
protein autophosphorylationGO:00467771230.012
negative regulation of phosphate metabolic processGO:00459362670.012
cell projection organizationGO:00300302520.012
segmentationGO:003528240.012
cellular lipid catabolic processGO:0044242650.012
circadian sleep wake cycle sleepGO:005080220.012
negative regulation of catabolic processGO:00098951040.012
monocarboxylic acid metabolic processGO:00327871850.012
heart morphogenesisGO:0003007480.012
regulation of cell cycleGO:00517263930.012
receptor metabolic processGO:0043112810.012
regulation of apoptotic signaling pathwayGO:20012331750.012
negative regulation of hydrogen peroxide induced cell deathGO:190320690.012
organic acid transportGO:0015849650.012
hexose metabolic processGO:0019318550.012
regulation of cell activationGO:00508651250.012
cholesterol transportGO:0030301390.011
innate immune responseGO:00450871780.011
negative regulation of platelet derived growth factor receptor signaling pathwayGO:001064240.011
cellular monovalent inorganic cation homeostasisGO:0030004260.011
divalent inorganic cation homeostasisGO:00725071360.011
regulation of cell divisionGO:00513021160.011
detection of stimulusGO:0051606850.011
extracellular matrix disassemblyGO:0022617160.011
regulation of endocytosisGO:0030100720.011
sequestering of metal ionGO:0051238240.011
cell substrate adhesionGO:00315891320.011
divalent inorganic cation transportGO:00725111580.011
ph reductionGO:0045851110.011
cell part morphogenesisGO:00329901370.011
erbb signaling pathwayGO:0038127440.011
regulation of secretion by cellGO:19035301770.011
response to estrogenGO:0043627470.011
cell adhesionGO:00071553250.011
decidualizationGO:004669740.011
positive regulation of cell deathGO:00109422630.011
modification dependent macromolecule catabolic processGO:00436322120.011
actin filament based processGO:00300292240.011
negative regulation of cell cycleGO:00457861930.010
involuntary skeletal muscle contractionGO:000301110.010
monosaccharide metabolic processGO:0005996740.010
negative regulation of synaptic transmissionGO:005080520.010
mitotic cell cycleGO:00002783260.010
negative regulation of organelle organizationGO:00106391260.010
syncytium formation by plasma membrane fusionGO:000076820.010
secretionGO:00469032540.010
endocrine processGO:0050886250.010
Human
cellular macromolecular complex assemblyGO:00346223240.010
behaviorGO:00076101120.010
erk1 and erk2 cascadeGO:00703711040.010
metencephalon developmentGO:002203720.010

CTSD disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.986
disease of metabolismDOID:00146672950.986
lysosomal storage diseaseDOID:3211470.961
lipid storage diseaseDOID:9455280.961
nervous system diseaseDOID:8634310.595
central nervous system diseaseDOID:3311860.595
brain diseaseDOID:936730.299
cerebral degenerationDOID:1443160.299
leukodystrophyDOID:1057980.299
neuronal ceroid lipofuscinosisDOID:14503110.209
neurodegenerative diseaseDOID:12891020.101
eye and adnexa diseaseDOID:14921500.044
eye diseaseDOID:56141490.044
sensory system diseaseDOID:00501552030.044
acquired metabolic diseaseDOID:0060158580.042
carbohydrate metabolic disorderDOID:2978550.041
glycogen metabolism disorderDOID:0050728100.041
degeneration of macula and posterior poleDOID:2007170.030
retinal diseaseDOID:56791180.030
retinal degenerationDOID:8466890.030
macular degenerationDOID:4448200.030
cognitive disorderDOID:1561290.029
disease of mental healthDOID:150700.029
sphingolipidosisDOID:1927140.028
glycogen storage diseaseDOID:2747100.024
immune system diseaseDOID:29141550.021
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
musculoskeletal system diseaseDOID:172230.012
disease by infectious agentDOID:0050117340.012
age related macular degenerationDOID:10871170.011
hematopoietic system diseaseDOID:741000.010
cardiovascular system diseaseDOID:12871060.010