Homo sapiens

57 known processes

USP28

ubiquitin specific peptidase 28

(Aliases: KIAA1515)

USP28 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification by small protein removalGO:0070646920.178
protein deubiquitinationGO:0016579790.140
protein k63 linked deubiquitinationGO:0070536210.073
Human
response to abiotic stimulusGO:00096283360.061
cellular amino acid metabolic processGO:00065201160.060
amine metabolic processGO:0009308440.051
cellular ketone metabolic processGO:0042180800.050
post embryonic developmentGO:000979120.048
regulation of cellular ketone metabolic processGO:0010565500.044
regulation of cellular amino acid metabolic processGO:000652160.042
regulation of cellular amine metabolic processGO:0033238110.042
apoptotic signaling pathwayGO:00971902680.041
cellular response to abiotic stimulusGO:00712141170.037
multicellular organismal agingGO:001025930.036
female gamete generationGO:000729220.036
cellular amine metabolic processGO:0044106410.036
cytoplasmic transportGO:00164823790.036
negative regulation of cellular protein metabolic processGO:00322693530.035
intrinsic apoptotic signaling pathwayGO:00971931270.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
determination of adult lifespanGO:000834020.034
mitotic cell cycleGO:00002783260.031
chromatin organizationGO:00063253510.030
mitotic cell cycle processGO:19030472860.030
negative regulation of catalytic activityGO:00430863350.029
positive regulation of cellular amine metabolic processGO:003324070.029
histone modificationGO:00165702510.029
neuromuscular junction developmentGO:000752830.029
cellular response to dna damage stimulusGO:00069743790.028
negative regulation of protein metabolic processGO:00512483910.028
oogenesisGO:004847720.028
protein catabolic processGO:00301633250.028
immune responseGO:00069553070.027
cell cycle checkpointGO:00000751170.027
positive regulation of catabolic processGO:00098963100.027
maintenance of locationGO:00512351120.026
proteolysis involved in cellular protein catabolic processGO:00516032440.026
purine ribonucleoside metabolic processGO:00461284370.026
negative regulation of developmental processGO:00510932470.025
regenerationGO:003109940.025
posttranscriptional regulation of gene expressionGO:00106082130.025
response to uvGO:0009411730.024
protein localization to organelleGO:00333652800.024
nucleoside triphosphate metabolic processGO:00091414220.024
cellular response to radiationGO:0071478650.024
membrane organizationGO:00610242920.023
positive regulation of cellular component organizationGO:00511303760.023
positive regulation of cellular catabolic processGO:00313312840.023
segmentationGO:003528240.023
organophosphate catabolic processGO:00464344300.023
purine containing compound catabolic processGO:00725234110.023
cellular macromolecular complex assemblyGO:00346223240.023
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
nucleotide catabolic processGO:00091664080.022
protein k48 linked deubiquitinationGO:0071108190.022
Human
response to light stimulusGO:0009416870.022
signal transduction by phosphorylationGO:00230142970.022
chromatin modificationGO:00165682980.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
purine nucleoside catabolic processGO:00061523980.022
regulation of kinase activityGO:00435493140.022
regulation of proteolysisGO:00301622930.021
response to ionizing radiationGO:0010212650.021
regulation of protein localizationGO:00328802960.021
ribonucleotide catabolic processGO:00092614050.021
protein maturationGO:00516042330.021
positive regulation of hydrolase activityGO:00513453310.020
nucleoside phosphate catabolic processGO:19012924120.020
protein modification by small protein conjugationGO:00324463420.020
negative regulation of phosphorus metabolic processGO:00105632670.020
nucleoside triphosphate catabolic processGO:00091433940.020
cellular lipid metabolic processGO:00442553030.020
ribonucleoside triphosphate metabolic processGO:00091994120.020
regulation of cell cycleGO:00517263930.020
regulation of cell differentiationGO:00455953930.020
endomembrane system organizationGO:00102561960.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
anterior posterior axis specificationGO:000994820.020
negative regulation of multicellular organismal processGO:00512413170.020
actin filament based processGO:00300292240.020
signal transduction by p53 class mediatorGO:0072331720.020
regulation of transferase activityGO:00513383550.020
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.020
ribonucleoside catabolic processGO:00424544060.020
small gtpase mediated signal transductionGO:0007264780.020
protein ubiquitinationGO:00165673140.020
positive regulation of transportGO:00510503360.019
transmembrane transportGO:00550853990.019
defense responseGO:00069523150.019
metal ion transportGO:00300012720.019
locomotory behaviorGO:000762610.019
cell projection organizationGO:00300302520.019
rho protein signal transductionGO:0007266260.019
adult locomotory behaviorGO:000834410.019
regulation of cell cycle processGO:00105642660.019
single organism membrane organizationGO:00448022680.019
chemical homeostasisGO:00488783060.019
proteasomal protein catabolic processGO:00104981760.019
carbohydrate derivative biosynthetic processGO:19011372070.019
modification dependent protein catabolic processGO:00199412090.019
cell morphogenesisGO:00009022960.019
memoryGO:000761330.019
carbohydrate metabolic processGO:00059752070.019
cellular macromolecule catabolic processGO:00442653800.019
purine ribonucleotide catabolic processGO:00091544040.019
ras protein signal transductionGO:0007265730.019
system processGO:00030083490.019
single organism cellular localizationGO:19025803320.019
negative regulation of programmed cell deathGO:00430693210.018
glycosyl compound catabolic processGO:19016584130.018
cellular response to uvGO:0034644320.018
rhythmic behaviorGO:000762220.018
blastoderm segmentationGO:000735020.018
oxidation reduction processGO:00551143960.018
oocyte developmentGO:004859910.018
negative regulation of phosphate metabolic processGO:00459362670.018
response to oxygen containing compoundGO:19017003690.018
microtubule based processGO:00070172100.018
positive regulation of immune system processGO:00026842830.018
biological adhesionGO:00226103310.018
regulation of protein kinase activityGO:00458592890.018
nervous system developmentGO:00073992930.018
Zebrafish
lipid metabolic processGO:00066293810.018
cellular protein catabolic processGO:00442572610.018
regulation of cellular component movementGO:00512703340.018
dephosphorylationGO:00163112090.018
cation transportGO:00068123310.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
negative regulation of hydrolase activityGO:00513461820.017
purine nucleotide catabolic processGO:00061954050.017
cellular response to endogenous stimulusGO:00714953360.017
negative regulation of cellular amine metabolic processGO:003323930.017
positive regulation of organelle organizationGO:00106381950.017
positive regulation of protein phosphorylationGO:00019343130.017
nucleoside catabolic processGO:00091644080.017
cellular component morphogenesisGO:00329893140.017
regulation of protein transportGO:00512232130.017
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.017
response to other organismGO:00517072610.017
ion transmembrane transportGO:00342203380.017
regulation of anatomical structure morphogenesisGO:00226032860.017
negative regulation of cell deathGO:00605483450.017
circadian behaviorGO:004851220.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
regulation of locomotionGO:00400123290.017
positive regulation of cell deathGO:00109422630.017
morphogenesis of embryonic epitheliumGO:001633140.017
positive regulation of developmental processGO:00510943140.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of protein catabolic processGO:00421761550.017
innate immune responseGO:00450871780.017
organonitrogen compound biosynthetic processGO:19015662000.017
positive regulation of apoptotic processGO:00430652460.017
mapk cascadeGO:00001652880.016
regulation of mitotic cell cycleGO:00073461890.016
protein processingGO:00164852260.016
positive regulation of cell proliferationGO:00082843010.016
regulation of response to external stimulusGO:00321012220.016
mitochondrion organizationGO:00070051560.016
purine ribonucleoside catabolic processGO:00461303980.016
protein targetingGO:00066051870.016
regulation of cytokine productionGO:00018172320.016
response to external biotic stimulusGO:00432072610.016
cardiac muscle cell contractionGO:008600340.016
negative regulation of intracellular signal transductionGO:19025321830.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of endopeptidase activityGO:00525481700.016
rna interferenceGO:001624640.016
negative regulation of cellular component organizationGO:00511292350.016
spermatid differentiationGO:004851540.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
regulation of cell migrationGO:00303342890.016
hindbrain developmentGO:003090230.016
regulation of nucleoside metabolic processGO:00091182090.016
secretionGO:00469032540.016
intracellular protein transportGO:00068862700.016
nitrogen compound transportGO:00717051910.016
negative regulation of cell proliferationGO:00082852280.016
regulation of establishment of protein localizationGO:00702012420.016
regulation of cell motilityGO:20001452990.016
oocyte differentiationGO:000999420.016
dna repairGO:00062811980.015
microtubule cytoskeleton organizationGO:00002261760.015
regulation of nucleotide metabolic processGO:00061402690.015
regulation of immune responseGO:00507762010.015
secretion by cellGO:00329402260.015
covalent chromatin modificationGO:00165692540.015
positive regulation of nucleotide metabolic processGO:00459812300.015
establishment of protein localization to organelleGO:00725941720.015
reactive oxygen species metabolic processGO:0072593750.015
response to axon injuryGO:004867810.015
nucleocytoplasmic transportGO:00069131760.015
compound eye developmentGO:004874910.015
peripheral nervous system developmentGO:000742220.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
positive regulation of transferase activityGO:00513472270.015
inner ear morphogenesisGO:004247240.015
negative regulation of protein modification processGO:00314002000.015
negative regulation of apoptotic processGO:00430663160.015
cellular homeostasisGO:00197251960.015
cell adhesionGO:00071553250.015
cellular protein complex assemblyGO:00436231880.015
regulation of purine nucleotide metabolic processGO:19005422640.015
tripartite regional subdivisionGO:000735120.015
single organism carbohydrate metabolic processGO:00447231930.015
glycoprotein metabolic processGO:00091001100.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
cellular response to oxygen containing compoundGO:19017012760.014
associative learningGO:000830610.014
reactive oxygen species biosynthetic processGO:190340940.014
lipid biosynthetic processGO:00086101770.014
negative regulation of proteolysisGO:00458611320.014
matingGO:000761810.014
growthGO:00400072020.014
regulation of meiotic cell cycleGO:005144540.014
response to radiationGO:00093141510.014
nuclear transportGO:00511691790.014
metencephalon developmentGO:002203720.014
small molecule biosynthetic processGO:00442831570.014
guanosine containing compound catabolic processGO:19010692390.014
regulation of cellular response to stressGO:00801352440.014
cellular response to light stimulusGO:0071482340.014
regulation of synaptic plasticityGO:004816730.014
regulation of secretionGO:00510461940.014
motor neuron axon guidanceGO:000804520.014
negative regulation of protein processingGO:00109551420.014
actin mediated cell contractionGO:0070252120.014
cation transmembrane transportGO:00986552380.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of intracellular transportGO:00323861950.014
vesicle mediated transportGO:00161923710.014
reactive nitrogen species metabolic processGO:200105730.014
tissue regenerationGO:004224630.014
regulation of growthGO:00400081650.013
ubiquitin dependent protein catabolic processGO:00065112060.013
regulation of peptidase activityGO:00525471800.013
anterior posterior axis specification embryoGO:000859520.013
nuclear divisionGO:00002801280.013
spermatid developmentGO:000728640.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
regulation of purine nucleotide catabolic processGO:00331212050.013
circulatory system developmentGO:00723592620.013
embryonic epithelial tube formationGO:000183840.013
organ formationGO:004864530.013
protein oligomerizationGO:00512591730.013
organelle assemblyGO:00709251760.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
mitotic nuclear divisionGO:00070671190.013
positive regulation of phosphorylationGO:00423273940.013
regulation of protein maturationGO:19033171500.013
chromosome segregationGO:00070591140.013
response to fungusGO:000962040.013
regulation of protein processingGO:00706131500.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
actin filament based movementGO:0030048170.013
response to biotic stimulusGO:00096072760.013
regulation of dna metabolic processGO:00510521530.013
regulation of homeostatic processGO:00328441210.013
ion homeostasisGO:00508012300.013
response to cytokineGO:00340972320.013
regulation of cytoskeleton organizationGO:00514931770.013
inorganic ion transmembrane transportGO:00986602310.013
negative regulation of protein maturationGO:19033181420.013
monocarboxylic acid metabolic processGO:00327871850.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of neural precursor cell proliferationGO:200017740.013
negative regulation of cell differentiationGO:00455961710.013
cellular cation homeostasisGO:00300031630.013
sequestering of metal ionGO:0051238240.013
negative regulation of cell cycleGO:00457861930.013
cell fate determinationGO:000170930.013
positive regulation of kinase activityGO:00336742040.013
regulation of mapk cascadeGO:00434082620.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
cell divisionGO:00513011680.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
inorganic cation transmembrane transportGO:00986621940.013
positive regulation of proteolysisGO:00458621420.013
cytokine productionGO:00018162470.013
neurotransmitter secretionGO:000726940.012
cellular response to cytokine stimulusGO:00713451810.012
cell growthGO:00160491600.012
regulation of multi organism processGO:00439001570.012
nerve developmentGO:002167540.012
negative regulation of phosphorylationGO:00423261740.012
limbic system developmentGO:002176130.012
positive regulation of nucleotide catabolic processGO:00308131850.012
anion transportGO:00068201610.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
rna splicingGO:00083801310.012
endosomal transportGO:00161971290.012
positive regulation of protein transportGO:00512221350.012
cation homeostasisGO:00550801890.012
neural tube formationGO:000184130.012
positive regulation of cell differentiationGO:00455972110.012
positive regulation of synaptic transmissionGO:005080640.012
mitotic cell cycle phase transitionGO:00447721620.012
response to growth factorGO:00708482050.012
wnt signaling pathwayGO:00160551560.012
sequestering of calcium ionGO:0051208170.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
cell developmentGO:00484683280.012
cell projection assemblyGO:00300311260.012
syncytium formation by plasma membrane fusionGO:000076820.012
neurological system processGO:00508771630.012
sex determinationGO:000753030.012
guanosine containing compound metabolic processGO:19010682440.012
cofactor metabolic processGO:0051186870.012
divalent inorganic cation transportGO:00725111580.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
positive regulation of cytokine productionGO:00018191670.012
regulation of secretion by cellGO:19035301770.012
morphogenesis of a polarized epitheliumGO:000173830.012
metal ion homeostasisGO:00550651690.012
atp metabolic processGO:00460341760.012
multi organism cellular processGO:00447641560.012
organophosphate biosynthetic processGO:00904071630.012
modification dependent macromolecule catabolic processGO:00436322120.012
single organism cell adhesionGO:00986021790.012
cerebellum developmentGO:002154920.012
negative regulation of transportGO:00510511760.012
rna processingGO:00063962550.012
gtp catabolic processGO:00061842370.012
photoreceptor cell differentiationGO:004653020.012
gtp metabolic processGO:00460392390.012
cardiovascular system developmentGO:00723582620.011
meiosis iGO:000712740.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
positive regulation of cellular component movementGO:00512721810.011
cell projection morphogenesisGO:00488581290.011
spinal cord developmentGO:002151040.011
endocytosisGO:00068971590.011
interspecies interaction between organismsGO:00444191560.011
regulation of apoptotic signaling pathwayGO:20012331750.011
nucleoside monophosphate metabolic processGO:00091231910.011
protein localization to nucleusGO:00345041360.011
protein importGO:00170381300.011
engulfment of apoptotic cellGO:004365220.011
thymus developmentGO:004853830.011
regulation of protein complex assemblyGO:00432541470.011
calcium ion transportGO:00068161470.011
carboxylic acid biosynthetic processGO:0046394970.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
glycoprotein biosynthetic processGO:0009101910.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of nucleotide catabolic processGO:00308112050.011
meiotic chromosome segregationGO:004513240.011
positive regulation of protein kinase activityGO:00458601900.011
cell part morphogenesisGO:00329901370.011
negative regulation of organelle organizationGO:00106391260.011
regulation of defense responseGO:00313471540.011
long term memoryGO:000761620.011
positive regulation of cell migrationGO:00303351720.011
cellular metal ion homeostasisGO:00068751460.011
neuroblast proliferationGO:000740540.011
central nervous system developmentGO:00074171230.011
Zebrafish
regulation of protein serine threonine kinase activityGO:00719001790.011
regulation of cell morphogenesisGO:00226041530.011
tube closureGO:006060630.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
defense response to fungusGO:005083240.011
actin cytoskeleton organizationGO:00300362070.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of cytoplasmic transportGO:19036491490.011
positive regulation of cell cycleGO:00457871400.011
response to woundingGO:00096111680.011
salivary gland morphogenesisGO:000743540.011
methylationGO:00322591060.011
regulation of actin filament based processGO:00329701410.011
regulation of gtp catabolic processGO:00331241800.011
regulation of gtpase activityGO:00430871800.011
embryo developmentGO:00097901230.011
peptidyl tyrosine modificationGO:00182121700.011
divalent metal ion transportGO:00708381520.011
positive regulation of immune responseGO:00507781590.011
epithelium developmentGO:00604292270.011
sensory perception of painGO:001923340.011
neuron projection regenerationGO:003110210.010
single organism reproductive processGO:0044702980.010
response to nitrogen compoundGO:19016981840.010
epithelial cell differentiationGO:00308551410.010
macromolecule glycosylationGO:0043413630.010
organic acid biosynthetic processGO:0016053970.010
visual behaviorGO:000763220.010
regulation of ion transportGO:00432691890.010
sleepGO:003043120.010
regulation of cell divisionGO:00513021160.010
cellular chemical homeostasisGO:00550821800.010
negative regulation of transferase activityGO:00513481240.010
cell cycle phase transitionGO:00447701730.010
axon regenerationGO:003110310.010
positive regulation of transcription during mitosisGO:004589720.010
generation of neuronsGO:00486991520.010
pituitary gland developmentGO:002198320.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
positive regulation of secretionGO:00510471160.010
organelle fissionGO:00482851490.010
myoblast fusionGO:000752010.010
t cell differentiation in thymusGO:003307740.010
negative regulation of cell cycle processGO:00109481210.010

USP28 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.037
inherited metabolic disorderDOID:6552420.025
nervous system diseaseDOID:8634310.025
sensory system diseaseDOID:00501552030.025
musculoskeletal system diseaseDOID:172230.023
central nervous system diseaseDOID:3311860.021
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.017
muscular diseaseDOID:00800001140.015
immune system diseaseDOID:29141550.015
bone diseaseDOID:0080001880.013
connective tissue diseaseDOID:651090.013
myopathyDOID:4231040.013
muscle tissue diseaseDOID:661130.013
neurodegenerative diseaseDOID:12891020.012
brain diseaseDOID:936730.011
hematopoietic system diseaseDOID:741000.011
retinal diseaseDOID:56791180.011
disease of mental healthDOID:150700.011
cardiovascular system diseaseDOID:12871060.011
retinal degenerationDOID:8466890.011
amino acid metabolic disorderDOID:9252500.010