Homo sapiens

0 known processes

PENK

proenkephalin

PENK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of multicellular organismal processGO:00512413170.155
cellular ketone metabolic processGO:0042180800.148
regulation of cellular amine metabolic processGO:0033238110.147
cellular amine metabolic processGO:0044106410.147
cellular amino acid metabolic processGO:00065201160.128
regulation of cell differentiationGO:00455953930.113
amine metabolic processGO:0009308440.113
enzyme linked receptor protein signaling pathwayGO:00071673030.109
positive regulation of cell proliferationGO:00082843010.108
regulation of locomotionGO:00400123290.105
positive regulation of cellular amino acid metabolic processGO:004576430.103
locomotory behaviorGO:000762610.102
regulation of cellular component movementGO:00512703340.101
system processGO:00030083490.100
regulation of cellular amino acid metabolic processGO:000652160.099
regulation of cellular ketone metabolic processGO:0010565500.098
regulation of anatomical structure morphogenesisGO:00226032860.090
regulation of cell migrationGO:00303342890.087
cellular response to endogenous stimulusGO:00714953360.085
secretionGO:00469032540.081
positive regulation of transportGO:00510503360.078
secretion by cellGO:00329402260.078
positive regulation of developmental processGO:00510943140.075
signal transduction by phosphorylationGO:00230142970.073
nervous system developmentGO:00073992930.072
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.071
response to oxygen containing compoundGO:19017003690.070
cell morphogenesisGO:00009022960.070
circulatory system developmentGO:00723592620.067
positive regulation of cellular component organizationGO:00511303760.067
post embryonic developmentGO:000979120.065
regulation of cell motilityGO:20001452990.065
positive regulation of mapk cascadeGO:00434101900.062
positive regulation of cellular amine metabolic processGO:003324070.061
anatomical structure formation involved in morphogenesisGO:00486462840.060
cell developmentGO:00484683280.060
cellular response to oxygen containing compoundGO:19017012760.058
positive regulation of hydrolase activityGO:00513453310.057
glycosyl compound catabolic processGO:19016584130.057
regulation of response to external stimulusGO:00321012220.054
ion homeostasisGO:00508012300.054
negative regulation of developmental processGO:00510932470.053
neuron differentiationGO:00301821380.053
positive regulation of phosphorylationGO:00423273940.052
positive regulation of nucleotide metabolic processGO:00459812300.052
regulation of hormone levelsGO:00108171250.051
negative regulation of cell proliferationGO:00082852280.051
negative regulation of protein metabolic processGO:00512483910.050
mapk cascadeGO:00001652880.050
response to lipidGO:00339932060.050
chemical homeostasisGO:00488783060.049
regulation of secretionGO:00510461940.049
spinal cord developmentGO:002151040.048
regulation of cellular component biogenesisGO:00440872810.048
single organism cellular localizationGO:19025803320.048
negative regulation of transportGO:00510511760.048
response to abiotic stimulusGO:00096283360.048
positive regulation of epithelial cell proliferationGO:0050679650.047
growthGO:00400072020.047
cell cell signalingGO:00072671550.047
negative regulation of cell deathGO:00605483450.046
small gtpase mediated signal transductionGO:0007264780.046
hindbrain developmentGO:003090230.046
vesicle mediated transportGO:00161923710.046
g protein coupled receptor signaling pathwayGO:00071862070.046
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.046
regulation of secretion by cellGO:19035301770.046
ras protein signal transductionGO:0007265730.045
negative regulation of programmed cell deathGO:00430693210.045
regulation of nucleotide metabolic processGO:00061402690.045
negative regulation of apoptotic processGO:00430663160.044
generation of neuronsGO:00486991520.044
segmentationGO:003528240.044
positive regulation of protein phosphorylationGO:00019343130.044
cellular component morphogenesisGO:00329893140.044
negative regulation of catalytic activityGO:00430863350.044
positive regulation of cell differentiationGO:00455972110.044
cyclic nucleotide metabolic processGO:0009187820.043
regulation of cell cycleGO:00517263930.043
blood vessel developmentGO:00015681720.043
defense responseGO:00069523150.043
regulation of transferase activityGO:00513383550.043
regulation of mapk cascadeGO:00434082620.042
cell adhesionGO:00071553250.042
cardiovascular system developmentGO:00723582620.042
response to growth factorGO:00708482050.042
ion transmembrane transportGO:00342203380.042
regulation of protein localizationGO:00328802960.042
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.042
positive regulation of locomotionGO:00400171860.041
positive regulation of cell motilityGO:20001471770.041
cellular lipid metabolic processGO:00442553030.041
regulation of kinase activityGO:00435493140.040
cellular metal ion homeostasisGO:00068751460.040
ribonucleoside triphosphate catabolic processGO:00092033910.040
carbohydrate derivative biosynthetic processGO:19011372070.040
regulation of protein transportGO:00512232130.039
positive regulation of cellular component movementGO:00512721810.039
single organism membrane organizationGO:00448022680.039
multicellular organismal agingGO:001025930.039
regulation of establishment of protein localizationGO:00702012420.039
regulation of purine nucleotide metabolic processGO:19005422640.038
cellular response to growth factor stimulusGO:00713631970.038
organophosphate biosynthetic processGO:00904071630.038
negative regulation of phosphorus metabolic processGO:00105632670.038
purine ribonucleotide catabolic processGO:00091544040.038
cytokine productionGO:00018162470.038
morphogenesis of embryonic epitheliumGO:001633140.038
nucleoside phosphate biosynthetic processGO:19012931090.038
purine nucleotide catabolic processGO:00061954050.038
purine ribonucleoside triphosphate catabolic processGO:00092073910.037
positive regulation of apoptotic processGO:00430652460.037
cell projection organizationGO:00300302520.037
non canonical wnt signaling pathway via mapk cascadeGO:003803040.037
organonitrogen compound biosynthetic processGO:19015662000.037
positive regulation of synaptic transmissionGO:005080640.037
cytoplasmic transportGO:00164823790.037
vasculature developmentGO:00019441810.036
immune responseGO:00069553070.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.036
positive regulation of programmed cell deathGO:00430682490.036
negative regulation of phosphate metabolic processGO:00459362670.036
negative regulation of cell migrationGO:00303361020.036
organophosphate catabolic processGO:00464344300.036
female gamete generationGO:000729220.036
membrane organizationGO:00610242920.035
metal ion transportGO:00300012720.035
purine nucleoside catabolic processGO:00061523980.035
regulation of protein kinase activityGO:00458592890.035
cation transportGO:00068123310.035
positive regulation of purine nucleotide metabolic processGO:19005442270.035
response to hormoneGO:00097251750.035
negative regulation of cellular protein metabolic processGO:00322693530.035
ossificationGO:00015031210.035
purine ribonucleoside catabolic processGO:00461303980.034
divalent inorganic cation homeostasisGO:00725071360.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
cellular ion homeostasisGO:00068731680.034
determination of adult lifespanGO:000834020.034
response to organic cyclic compoundGO:00140702040.034
memoryGO:000761330.034
oogenesisGO:004847720.034
cellular homeostasisGO:00197251960.034
regulation of sequence specific dna binding transcription factor activityGO:00510902110.034
brain developmentGO:0007420970.034
urogenital system developmentGO:0001655650.034
lipid metabolic processGO:00066293810.033
regulation of response to woundingGO:19030341010.033
ribonucleoside catabolic processGO:00424544060.033
neurogenesisGO:00220081690.033
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.033
blood vessel morphogenesisGO:00485141620.033
negative regulation of cellular component organizationGO:00511292350.033
camp biosynthetic processGO:0006171470.033
positive regulation of transferase activityGO:00513472270.033
actin filament based processGO:00300292240.033
regulation of cellular response to stressGO:00801352440.033
neurological system processGO:00508771630.033
regulation of growthGO:00400081650.032
cell morphogenesis involved in differentiationGO:00009041440.032
inorganic cation transmembrane transportGO:00986621940.032
negative regulation of cell differentiationGO:00455961710.032
intracellular protein transportGO:00068862700.032
regulation of intracellular transportGO:00323861950.031
nucleoside triphosphate metabolic processGO:00091414220.031
nucleoside triphosphate catabolic processGO:00091433940.031
positive regulation of organelle organizationGO:00106381950.031
purine containing compound catabolic processGO:00725234110.031
regulation of cyclic nucleotide metabolic processGO:0030799630.031
canonical wnt signaling pathwayGO:00600701160.031
metal ion homeostasisGO:00550651690.031
epithelium developmentGO:00604292270.031
positive regulation of cell deathGO:00109422630.031
nucleotide catabolic processGO:00091664080.031
purine ribonucleotide biosynthetic processGO:0009152790.031
neuron fate commitmentGO:004866320.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
transmembrane transportGO:00550853990.030
anterior posterior axis specification embryoGO:000859520.030
multicellular organismal response to stressGO:003355510.030
sex determinationGO:000753030.030
wnt signaling pathwayGO:00160551560.030
cellular macromolecular complex assemblyGO:00346223240.030
regulation of nucleoside metabolic processGO:00091182090.030
nucleoside catabolic processGO:00091644080.029
regulation of canonical wnt signaling pathwayGO:0060828880.029
neuron projection developmentGO:00311751060.029
cell activationGO:00017752130.029
positive regulation of cell migrationGO:00303351720.029
apoptotic signaling pathwayGO:00971902680.029
response to woundingGO:00096111680.029
guanosine containing compound catabolic processGO:19010692390.029
regulation of ion transportGO:00432691890.029
positive regulation of protein kinase activityGO:00458601900.029
positive regulation of catabolic processGO:00098963100.029
central nervous system developmentGO:00074171230.029
regulation of cytokine productionGO:00018172320.029
positive regulation of cellular catabolic processGO:00313312840.029
peptidyl tyrosine phosphorylationGO:00181081700.029
regulation of epithelial cell proliferationGO:00506781130.029
regulation of peptidase activityGO:00525471800.029
protein modification by small protein conjugationGO:00324463420.029
regenerationGO:003109940.028
purine ribonucleoside metabolic processGO:00461284370.028
lipid biosynthetic processGO:00086101770.028
positive regulation of nucleotide catabolic processGO:00308131850.028
regulation of protein serine threonine kinase activityGO:00719001790.028
nucleoside phosphate catabolic processGO:19012924120.028
biological adhesionGO:00226103310.028
protein localization to organelleGO:00333652800.028
head developmentGO:00603221080.028
blastoderm segmentationGO:000735020.028
cation homeostasisGO:00550801890.027
second messenger mediated signalingGO:0019932780.027
ribonucleotide catabolic processGO:00092614050.027
camp metabolic processGO:0046058610.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
cellular divalent inorganic cation homeostasisGO:00725031280.027
gtp catabolic processGO:00061842370.027
cellular macromolecule catabolic processGO:00442653800.027
angiogenesisGO:00015251470.027
gtp metabolic processGO:00460392390.027
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.026
regulation of cell morphogenesisGO:00226041530.026
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.026
digestive system developmentGO:0055123750.026
neuron developmentGO:00486661130.026
regulation of cytoskeleton organizationGO:00514931770.026
embryonic epithelial tube formationGO:000183840.026
regulation of actin filament based processGO:00329701410.026
regulation of proteolysisGO:00301622930.026
cellular chemical homeostasisGO:00550821800.026
response to organonitrogen compoundGO:00102431560.026
regulation of membrane potentialGO:0042391950.026
regulation of synaptic plasticityGO:004816730.026
ameboidal type cell migrationGO:00016671350.026
endomembrane system organizationGO:00102561960.026
inorganic ion transmembrane transportGO:00986602310.026
associative learningGO:000830610.025
negative regulation of gliogenesisGO:001401430.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.025
nitrogen compound transportGO:00717051910.025
positive regulation of nucleoside metabolic processGO:00459791860.025
forelimb morphogenesisGO:003513640.025
hormone secretionGO:0046879650.025
limbic system developmentGO:002176130.025
tube developmentGO:00352951250.025
regulation of cytoplasmic transportGO:19036491490.025
cardiac muscle cell contractionGO:008600340.025
regulation of gtp catabolic processGO:00331241800.025
tissue morphogenesisGO:0048729960.025
wound healingGO:00420601150.024
regulation of wnt signaling pathwayGO:00301111230.024
cellular cation homeostasisGO:00300031630.024
specification of organ identityGO:001009230.024
negative regulation of locomotionGO:00400131180.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
regulation of cell developmentGO:00602841610.024
organ morphogenesisGO:00098871470.024
response to nitrogen compoundGO:19016981840.024
response to other organismGO:00517072610.024
behaviorGO:00076101120.024
negative regulation of cellular amine metabolic processGO:003323930.024
purine nucleotide biosynthetic processGO:0006164840.024
regulation of homeostatic processGO:00328441210.024
osteoblast differentiationGO:0001649920.024
positive regulation of secretion by cellGO:19035321080.024
motor neuron axon guidanceGO:000804520.024
epithelial cell proliferationGO:00506731280.024
regulation of cell cycle processGO:00105642660.024
rhythmic behaviorGO:000762220.023
cellular response to organonitrogen compoundGO:00714171240.023
actin cytoskeleton organizationGO:00300362070.023
guanosine containing compound metabolic processGO:19010682440.023
calcium ion homeostasisGO:00550741220.023
nucleotide biosynthetic processGO:00091651090.023
organ formationGO:004864530.023
mitotic cell cycleGO:00002783260.023
regulation of transmembrane transporter activityGO:0022898740.023
positive regulation of ras gtpase activityGO:00323201170.023
renal system developmentGO:0072001630.023
cell fate determinationGO:000170930.023
chemotaxisGO:00069351570.023
protein localization to membraneGO:00726571600.023
peptidyl tyrosine modificationGO:00182121700.023
regulation of endopeptidase activityGO:00525481700.022
neuromuscular junction developmentGO:000752830.022
circadian behaviorGO:004851220.022
positive regulation of erk1 and erk2 cascadeGO:0070374750.022
response to external biotic stimulusGO:00432072610.022
digestive tract developmentGO:0048565750.022
lung alveolus developmentGO:004828640.022
anterior posterior axis specificationGO:000994820.022
matingGO:000761810.022
tripartite regional subdivisionGO:000735120.022
protein catabolic processGO:00301633250.022
regulation of cyclic nucleotide biosynthetic processGO:0030802490.022
regulation of ion transmembrane transportGO:00347651320.022
pituitary gland developmentGO:002198320.022
carbohydrate metabolic processGO:00059752070.022
divalent inorganic cation transportGO:00725111580.022
regulation of gtpase activityGO:00430871800.022
regulation of metal ion transportGO:00109591200.022
cell growthGO:00160491600.021
somatic stem cell maintenanceGO:003501940.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
positive regulation of wnt signaling pathwayGO:0030177540.021
purine containing compound biosynthetic processGO:0072522880.021
cellular response to dna damage stimulusGO:00069743790.021
regulation of nucleotide catabolic processGO:00308112050.021
negative regulation of hydrolase activityGO:00513461820.021
chromatin organizationGO:00063253510.021
positive regulation of kinase activityGO:00336742040.021
posttranscriptional regulation of gene expressionGO:00106082130.021
neural crest cell developmentGO:001403230.021
somitogenesisGO:000175620.021
negative regulation of protein modification processGO:00314002000.021
neural tube formationGO:000184130.021
ribonucleotide biosynthetic processGO:0009260810.021
anion transportGO:00068201610.021
regulation of defense responseGO:00313471540.021
muscle system processGO:0003012810.021
positive regulation of secretionGO:00510471160.021
response to biotic stimulusGO:00096072760.021
cellular response to nitrogen compoundGO:19016991440.021
regulation of purine nucleotide catabolic processGO:00331212050.021
single organism carbohydrate metabolic processGO:00447231930.020
positive regulation of cytokine productionGO:00018191670.020
positive regulation of immune system processGO:00026842830.020
cell projection morphogenesisGO:00488581290.020
regulation of camp metabolic processGO:0030814520.020
oxidation reduction processGO:00551143960.020
regulation of map kinase activityGO:00434051080.020
innate immune responseGO:00450871780.020
regulation of apoptotic signaling pathwayGO:20012331750.020
regulation of vasculature developmentGO:1901342970.020
thymus developmentGO:004853830.020
metencephalon developmentGO:002203720.020
protein targetingGO:00066051870.020
muscle structure developmentGO:0061061980.020
blood circulationGO:00080151130.020
positive regulation of gtp catabolic processGO:00331261660.020
taxisGO:00423301570.020
sequestering of calcium ionGO:0051208170.020
regulation of ras protein signal transductionGO:00465781550.020
ribose phosphate biosynthetic processGO:0046390820.020
cyclic nucleotide biosynthetic processGO:0009190610.019
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.019
cellular protein catabolic processGO:00442572610.019
glycoprotein metabolic processGO:00091001100.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
cellular response to organic cyclic compoundGO:00714071270.019
nerve developmentGO:002167540.019
leukocyte activationGO:00453211640.019
adult locomotory behaviorGO:000834410.019
regulation of sodium dependent phosphate transportGO:200011820.019
immune system developmentGO:00025201950.019
sensory perception of painGO:001923340.019
response to bacteriumGO:00096171440.019
nuclear transportGO:00511691790.019
mitotic cell cycle processGO:19030472860.019
eye developmentGO:0001654420.019
hematopoietic or lymphoid organ developmentGO:00485341860.019
cell type specific apoptotic processGO:00972851250.019
response to cytokineGO:00340972320.019
wnt signaling pathway calcium modulating pathwayGO:000722320.018
negative regulation of cell developmentGO:0010721480.018
epithelial cell migrationGO:00106311190.018
reactive nitrogen species metabolic processGO:200105730.018
negative regulation of immune system processGO:00026831360.018
negative regulation of secretionGO:0051048580.018
protein ubiquitinationGO:00165673140.018
endocytosisGO:00068971590.018
negative regulation of phosphorylationGO:00423261740.018
negative regulation of cellular component movementGO:00512711060.018
neuroblast proliferationGO:000740540.018
skeletal system developmentGO:0001501790.018
protein localization to nucleusGO:00345041360.018
positive regulation of camp biosynthetic processGO:0030819350.018
negative regulation of wnt signaling pathwayGO:0030178690.018
nucleocytoplasmic transportGO:00069131760.018
oocyte developmentGO:004859910.018
protein maturationGO:00516042330.018
regulation of body fluid levelsGO:0050878990.018
regulation of nervous system developmentGO:0051960880.018
establishment of protein localization to organelleGO:00725941720.018
primary neural tube formationGO:001402030.018
stem cell differentiationGO:0048863930.018
sensory organ developmentGO:0007423520.018
mesenchyme developmentGO:0060485590.018
synaptic transmissionGO:0007268610.018
positive regulation of gtpase activityGO:00435471660.018
muscle contractionGO:0006936730.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
receptor metabolic processGO:0043112810.018
small molecule biosynthetic processGO:00442831570.018
negative regulation of intracellular signal transductionGO:19025321830.018
regulation of purine nucleotide biosynthetic processGO:1900371500.018
regulation of immune responseGO:00507762010.018
sequestering of metal ionGO:0051238240.018
signal releaseGO:0023061700.018
chromatin modificationGO:00165682980.017
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131730.017
regulation of cell growthGO:00015581350.017
axis elongationGO:000340140.017
cellular response to lipidGO:00713961270.017
regulation of ion homeostasisGO:2000021730.017
circulatory system processGO:00030131130.017
cytosolic calcium ion homeostasisGO:0051480890.017
regulation of protein maturationGO:19033171500.017
compound eye developmentGO:004874910.017
neurotransmitter secretionGO:000726940.017
mesenchymal cell developmentGO:0014031500.017
synaptic transmission cholinergicGO:000727120.017
cell part morphogenesisGO:00329901370.017
dephosphorylationGO:00163112090.017
regulation of transporter activityGO:0032409820.017
tube morphogenesisGO:0035239950.017
organic hydroxy compound metabolic processGO:19016151470.017
negative regulation of canonical wnt signaling pathwayGO:0090090550.017
divalent metal ion transportGO:00708381520.017
regulation of mitotic cell cycleGO:00073461890.017
cyclic purine nucleotide metabolic processGO:0052652600.017
positive regulation of cytosolic calcium ion concentrationGO:0007204820.017
protein processingGO:00164852260.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
negative regulation of growthGO:0045926970.017
reactive oxygen species biosynthetic processGO:190340940.017
cellular response to cytokine stimulusGO:00713451810.017
microtubule cytoskeleton organizationGO:00002261760.017
negative regulation of cell motilityGO:20001461040.016
tissue regenerationGO:004224630.016
somatic muscle developmentGO:000752510.016
negative regulation of cell cycleGO:00457861930.016
spermatid differentiationGO:004851540.016
pharynx developmentGO:006046510.016
forebrain neuron differentiationGO:002187930.016
negative regulation of protein phosphorylationGO:00019331400.016
cellular response to glucocorticoid stimulusGO:007138540.016
cellular protein complex assemblyGO:00436231880.016
embryonic morphogenesisGO:0048598850.016
morphogenesis of a polarized epitheliumGO:000173830.016
cation transmembrane transportGO:00986552380.016
rho protein signal transductionGO:0007266260.016
positive regulation of cyclic nucleotide metabolic processGO:0030801490.016
oocyte differentiationGO:000999420.016
negative regulation of cell fate commitmentGO:001045430.016
extrinsic apoptotic signaling pathwayGO:00971911190.016
intracellular receptor signaling pathwayGO:00305221040.016
reproductive processGO:00224141060.016
regulation of protein secretionGO:0050708860.016
maintenance of locationGO:00512351120.016
receptor internalizationGO:0031623430.016
regulation of neuron differentiationGO:0045664700.016
plasma membrane organizationGO:00070091150.016
regulation of neural precursor cell proliferationGO:200017740.016
stem cell developmentGO:0048864690.016
regulation of cysteine type endopeptidase activityGO:20001161270.016
spermatid developmentGO:000728640.016
regulation of ion transmembrane transporter activityGO:0032412720.016
microtubule based processGO:00070172100.016
regulation of cardiac muscle tissue growthGO:005502140.016
epithelial tube branching involved in lung morphogenesisGO:006044140.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of multi organism processGO:00439001570.016
positive regulation of cellular component biogenesisGO:00440891580.015
long term memoryGO:000761620.015
regulation of camp biosynthetic processGO:0030817450.015
negative regulation of organelle organizationGO:00106391260.015
regulation of protein catabolic processGO:00421761550.015
response to axon injuryGO:004867810.015
regulation of dna metabolic processGO:00510521530.015
ventral spinal cord developmentGO:002151710.015
regulation of ossificationGO:0030278580.015
regulation of transmembrane transportGO:00347621390.015
erk1 and erk2 cascadeGO:00703711040.015
mesenchymal cell differentiationGO:0048762520.015

PENK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.037
disease of cellular proliferationDOID:145661740.026
nervous system diseaseDOID:8634310.025
central nervous system diseaseDOID:3311860.025
sensory system diseaseDOID:00501552030.024
cancerDOID:1621670.024
disease of metabolismDOID:00146672950.023
muscular diseaseDOID:00800001140.021
muscle tissue diseaseDOID:661130.021
organ system cancerDOID:00506861640.020
connective tissue diseaseDOID:651090.018
myopathyDOID:4231040.016
inherited metabolic disorderDOID:6552420.016
cardiovascular system diseaseDOID:12871060.016
eye and adnexa diseaseDOID:14921500.016
eye diseaseDOID:56141490.016