Homo sapiens

163 known processes

BIRC5

baculoviral IAP repeat containing 5

(Aliases: API4,EPR-1)

BIRC5 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of microtubule based processGO:0032886740.966
histone serine phosphorylationGO:003540440.852
microtubule cytoskeleton organizationGO:00002261760.851
Mouse
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.833
spindle midzone assemblyGO:005125540.832
regulation of microtubule cytoskeleton organizationGO:0070507610.818
microtubule polymerization or depolymerizationGO:0031109370.815
sister chromatid segregationGO:0000819540.814
spindle assemblyGO:0051225290.801
protein depolymerizationGO:0051261300.594
regulation of microtubule polymerization or depolymerizationGO:0031110270.580
regulation of cell cycleGO:00517263930.571
negative regulation of apoptotic processGO:00430663160.539
positive regulation of cell cycleGO:00457871400.492
spindle assembly involved in mitosisGO:0090307120.462
spindle organizationGO:0007051530.459
chromatin modificationGO:00165682980.439
covalent chromatin modificationGO:00165692540.412
positive regulation of cell cycle processGO:00900681060.379
negative regulation of cytoskeleton organizationGO:0051494450.358
centrosome organizationGO:0051297580.353
mitotic cell cycleGO:00002783260.350
protein complex disassemblyGO:0043241520.349
chromosome segregationGO:00070591140.349
regulation of chromosome segregationGO:0051983440.331
microtubule depolymerizationGO:0007019180.326
regulation of spindle organizationGO:0090224100.326
microtubule based processGO:00070172100.323
Mouse
centrosome separationGO:005129930.318
circulatory system developmentGO:00723592620.311
mitotic nuclear divisionGO:00070671190.305
organelle assemblyGO:00709251760.294
histone phosphorylationGO:0016572160.288
negative regulation of protein depolymerizationGO:1901880170.284
chromatin organizationGO:00063253510.262
histone modificationGO:00165702510.252
cell divisionGO:00513011680.214
organelle fissionGO:00482851490.212
spindle stabilizationGO:004314640.206
negative regulation of organelle organizationGO:00106391260.197
cellular protein complex disassemblyGO:0043624360.195
mitotic sister chromatid segregationGO:0000070530.193
peptidyl serine phosphorylationGO:00181051010.192
centrosome duplicationGO:0051298280.191
negative regulation of cellular protein metabolic processGO:00322693530.176
mitotic spindle elongationGO:000002240.172
single organism cellular localizationGO:19025803320.172
regulation of protein depolymerizationGO:1901879220.164
immune system developmentGO:00025201950.161
regulation of mitotic sister chromatid segregationGO:0033047270.153
negative regulation of phosphorus metabolic processGO:00105632670.152
response to hormoneGO:00097251750.146
negative regulation of cell cycle processGO:00109481210.138
cell type specific apoptotic processGO:00972851250.136
Mouse
regulation of protein complex assemblyGO:00432541470.129
dna repairGO:00062811980.127
mitotic cell cycle processGO:19030472860.123
cell cycle g2 m phase transitionGO:0044839430.123
dephosphorylationGO:00163112090.122
negative regulation of phosphate metabolic processGO:00459362670.119
protein dephosphorylationGO:0006470810.117
mitotic centrosome separationGO:000710010.115
mitotic sister chromatid separationGO:0051306180.111
cellular response to uvGO:0034644320.110
cell fate determinationGO:000170930.110
positive regulation of catabolic processGO:00098963100.110
positive regulation of cellular component organizationGO:00511303760.108
cellular component disassemblyGO:0022411920.102
regulation of cytoskeleton organizationGO:00514931770.101
spindle elongationGO:005123140.101
mitotic spindle midzone assemblyGO:005125640.099
regulation of cell cycle processGO:00105642660.096
negative regulation of protein metabolic processGO:00512483910.096
response to abiotic stimulusGO:00096283360.095
regulation of mitotic metaphase anaphase transitionGO:0030071260.095
proteolysis involved in cellular protein catabolic processGO:00516032440.093
post embryonic developmentGO:000979120.092
regulation of cell growthGO:00015581350.091
regulation of mitosisGO:0007088630.089
cellular response to endogenous stimulusGO:00714953360.089
mitotic cytokinesisGO:0000281190.089
negative regulation of protein maturationGO:19033181420.088
nucleocytoplasmic transportGO:00069131760.086
cytokinesisGO:0000910960.082
negative regulation of cellular component organizationGO:00511292350.081
positive regulation of exit from mitosisGO:003153620.080
negative regulation of proteolysisGO:00458611320.080
mitotic spindle organizationGO:0007052270.079
nuclear divisionGO:00002801280.077
regulation of kinase activityGO:00435493140.076
intracellular protein transportGO:00068862700.074
response to radiationGO:00093141510.071
positive regulation of cytokinesisGO:0032467290.069
negative regulation of b cell apoptotic processGO:000290340.067
negative regulation of protein processingGO:00109551420.066
negative regulation of phosphorylationGO:00423261740.065
cellular response to dna damage stimulusGO:00069743790.065
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.060
cyclin catabolic processGO:000805460.060
protein catabolic processGO:00301633250.059
protein localization to chromosomeGO:0034502300.059
protein processingGO:00164852260.058
organelle localizationGO:0051640840.055
immune responseGO:00069553070.055
regulation of cytokinesisGO:0032465450.055
negative regulation of catalytic activityGO:00430863350.054
organophosphate catabolic processGO:00464344300.054
response to oxidative stressGO:00069791210.052
regulation of protein processingGO:00706131500.051
regulation of cell divisionGO:00513021160.051
regulation of proteolysisGO:00301622930.050
cellular response to radiationGO:0071478650.048
meiotic nuclear divisionGO:0007126100.047
ubiquitin dependent protein catabolic processGO:00065112060.046
erythrocyte homeostasisGO:0034101310.046
negative regulation of cell deathGO:00605483450.045
multicellular organismal agingGO:001025930.045
regulation of protein kinase activityGO:00458592890.045
actin cytoskeleton organizationGO:00300362070.044
cellular amine metabolic processGO:0044106410.044
modification dependent macromolecule catabolic processGO:00436322120.043
regulation of metaphase anaphase transition of cell cycleGO:1902099260.043
golgi inheritanceGO:004831320.043
response to uvGO:0009411730.041
regulation of protein localizationGO:00328802960.041
cellular response to abiotic stimulusGO:00712141170.040
response to light stimulusGO:0009416870.040
microtubule cytoskeleton organization involved in mitosisGO:1902850150.040
regulation of proteasomal protein catabolic processGO:0061136870.040
positive regulation of transferase activityGO:00513472270.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
metaphase plate congressionGO:0051310180.039
regulation of transferase activityGO:00513383550.039
actin filament based processGO:00300292240.038
heart developmentGO:0007507950.038
response to biotic stimulusGO:00096072760.038
lymphocyte apoptotic processGO:0070227200.038
regulation of myeloid cell differentiationGO:0045637810.038
establishment of chromosome localizationGO:0051303200.036
negative regulation of hydrolase activityGO:00513461820.036
cellular macromolecular complex assemblyGO:00346223240.036
regulation of cellular response to stressGO:00801352440.036
peptidyl serine modificationGO:00182091060.036
cell part morphogenesisGO:00329901370.035
metaphase anaphase transition of cell cycleGO:0044784210.035
protein localization to organelleGO:00333652800.034
negative regulation of developmental processGO:00510932470.033
regulation of lymphocyte apoptotic processGO:0070228150.033
response to external biotic stimulusGO:00432072610.033
positive regulation of phosphorylationGO:00423273940.033
endocytosisGO:00068971590.032
myeloid cell differentiationGO:00300991170.032
vesicle mediated transportGO:00161923710.032
establishment of ribosome localizationGO:003375340.031
ras protein signal transductionGO:0007265730.031
oocyte differentiationGO:000999420.031
positive regulation of developmental processGO:00510943140.031
establishment of cell polarityGO:0030010220.031
protein autophosphorylationGO:00467771230.030
negative regulation of programmed cell deathGO:00430693210.030
oocyte maturationGO:000155610.029
response to decreased oxygen levelsGO:0036293960.029
negative regulation of protein complex disassemblyGO:0043242200.029
cell cycle arrestGO:0007050710.029
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.029
positive regulation of proteolysisGO:00458621420.028
cytoplasmic transportGO:00164823790.028
cellular amino acid metabolic processGO:00065201160.028
microtubule organizing center organizationGO:0031023620.028
regulation of protein catabolic processGO:00421761550.028
purine nucleoside triphosphate metabolic processGO:00091444120.028
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.027
nervous system developmentGO:00073992930.027
ribonucleoside catabolic processGO:00424544060.027
regulation of protein bindingGO:0043393660.027
positive regulation of protein phosphorylationGO:00019343130.027
negative regulation of peptidase activityGO:0010466910.027
negative regulation of mitotic cell cycle phase transitionGO:1901991850.026
dna damage response signal transduction by p53 class mediatorGO:0030330440.026
macromolecular complex disassemblyGO:0032984600.026
centrosome cycleGO:0007098320.026
regulation of cell differentiationGO:00455953930.025
positive regulation of protein kinase activityGO:00458601900.025
cellular macromolecule catabolic processGO:00442653800.025
determination of adult lifespanGO:000834020.025
regulation of protein serine threonine kinase activityGO:00719001790.025
negative regulation of protein modification processGO:00314002000.025
negative regulation of cell cycleGO:00457861930.024
cytoskeleton dependent cytokinesisGO:0061640220.024
positive regulation of immune system processGO:00026842830.024
mitotic metaphase plate congressionGO:0007080140.024
regulation of bindingGO:00510981110.024
establishment of organelle localizationGO:0051656590.023
intrinsic apoptotic signaling pathwayGO:00971931270.023
regulation of dephosphorylationGO:0035303960.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
cell agingGO:0007569520.022
mitotic cell cycle phase transitionGO:00447721620.022
regulation of cytoplasmic transportGO:19036491490.022
cell cycle g1 s phase transitionGO:0044843800.022
mitotic chromosome condensationGO:0007076110.021
regulation of cellular amino acid metabolic processGO:000652160.021
deoxyribose phosphate metabolic processGO:001969260.021
negative regulation of microtubule depolymerizationGO:0007026120.021
negative regulation of protein phosphorylationGO:00019331400.021
small gtpase mediated signal transductionGO:0007264780.021
g2 m transition of mitotic cell cycleGO:0000086410.020
metaphase anaphase transition of mitotic cell cycleGO:0007091210.020
negative regulation of cellular catabolic processGO:0031330830.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.020
establishment of spindle localizationGO:0051293120.020
regulation of intracellular transportGO:00323861950.020
striated muscle myosin thick filament assemblyGO:007168820.020
receptor mediated endocytosisGO:0006898840.020
regulation of meiotic cell cycleGO:005144540.020
response to oxygen levelsGO:00704821000.019
leukocyte apoptotic processGO:0071887310.019
negative regulation of intracellular signal transductionGO:19025321830.019
regulation of immune responseGO:00507762010.019
positive regulation of cellular catabolic processGO:00313312840.019
purine ribonucleoside catabolic processGO:00461303980.019
regulation of chromosome organizationGO:00330441030.019
embryo developmentGO:00097901230.019
Mouse
neuron projection developmentGO:00311751060.018
regulation of nuclear divisionGO:0051783650.018
nucleoside phosphate catabolic processGO:19012924120.018
cellular response to hypoxiaGO:0071456510.018
regulation of cellular amine metabolic processGO:0033238110.018
regulation of attachment of spindle microtubules to kinetochoreGO:005198890.018
cellular protein catabolic processGO:00442572610.017
cell growthGO:00160491600.017
gtp metabolic processGO:00460392390.017
regulation of endopeptidase activityGO:00525481700.017
negative regulation of cell sizeGO:004579230.017
reproductionGO:0000003630.017
myosin filament organizationGO:003103320.016
regulation of centrosome cycleGO:0046605150.016
positive regulation of cell divisionGO:0051781590.016
regulation of mitotic sister chromatid separationGO:0010965270.016
dna conformation changeGO:00711031130.016
erythrocyte differentiationGO:0030218280.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
positive regulation of dna metabolic processGO:0051054730.016
signal transduction by phosphorylationGO:00230142970.015
ribosome assemblyGO:004225590.015
ribonucleoprotein complex localizationGO:007116640.015
protein maturationGO:00516042330.015
nuclear transportGO:00511691790.015
establishment of protein localization to organelleGO:00725941720.015
cell morphogenesisGO:00009022960.015
neurogenesisGO:00220081690.015
nucleotide biosynthetic processGO:00091651090.015
regulation of cellular ketone metabolic processGO:0010565500.015
cellular component morphogenesisGO:00329893140.015
negative regulation of immune system processGO:00026831360.014
regulation of microtubule depolymerizationGO:0031114120.014
regulation of protein maturationGO:19033171500.014
dna packagingGO:0006323770.014
protein localization to nucleusGO:00345041360.014
regulation of peptidase activityGO:00525471800.014
cellular protein complex assemblyGO:00436231880.014
tissue regenerationGO:004224630.014
regulation of mitotic cell cycleGO:00073461890.014
negative regulation of dephosphorylationGO:0035305630.014
positive regulation of mitosisGO:0045840250.014
negative regulation of cell cycle phase transitionGO:1901988890.014
nucleotide catabolic processGO:00091664080.014
regulation of cell cycle g1 s phase transitionGO:1902806420.014
negative regulation of cell growthGO:0030308830.013
regulation of anatomical structure sizeGO:00900661010.013
organophosphate biosynthetic processGO:00904071630.013
regenerationGO:003109940.013
rna interferenceGO:001624640.013
regulation of phosphatase activityGO:0010921810.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
oxidation reduction processGO:00551143960.013
protein targetingGO:00066051870.013
response to hypoxiaGO:0001666960.013
lymphocyte activationGO:00466491330.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
amine metabolic processGO:0009308440.012
regulation of establishment of protein localizationGO:00702012420.012
regulation of purine nucleotide metabolic processGO:19005422640.012
protein import into nucleusGO:00066061040.012
spermatid differentiationGO:004851540.012
reactive oxygen species metabolic processGO:0072593750.012
biological adhesionGO:00226103310.012
attachment of spindle microtubules to kinetochoreGO:0008608170.012
response to organic cyclic compoundGO:00140702040.012
cellular lipid metabolic processGO:00442553030.012
cellular response to hormone stimulusGO:00328701250.012
cellular response to oxygen levelsGO:0071453550.012
posttranscriptional regulation of gene expressionGO:00106082130.012
negative regulation of transportGO:00510511760.012
dna biosynthetic processGO:0071897400.012
meiosis iGO:000712740.011
homeostasis of number of cellsGO:0048872400.011
photoreceptor cell differentiationGO:004653020.011
regulation of lymphocyte activationGO:00512491030.011
regulation of mapk cascadeGO:00434082620.011
regulation of ras protein signal transductionGO:00465781550.011
defense responseGO:00069523150.011
regulation of protein dephosphorylationGO:0035304180.011
protein targeting to nucleusGO:00447441040.011
mapk cascadeGO:00001652880.011
spindle checkpointGO:0031577260.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
regulation of nervous system developmentGO:0051960880.011
regulation of cell activationGO:00508651250.011
female gamete generationGO:000729220.011
positive regulation of cellular amine metabolic processGO:003324070.011
regulation of intracellular protein transportGO:00331571230.011
negative regulation of protein kinase activityGO:0006469980.010
myosin filament assemblyGO:003103420.010
neuromuscular junction developmentGO:000752830.010
protein homooligomerizationGO:00512601000.010
positive regulation of hydrolase activityGO:00513453310.010
cellular response to light stimulusGO:0071482340.010
cell fate commitmentGO:0045165270.010

BIRC5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.013
cancerDOID:1621670.013