Homo sapiens

32 known processes

PI4K2A

phosphatidylinositol 4-kinase type 2 alpha

(Aliases: RP11-548K23.6,DKFZp761G1923,PIK42A,PI4KII)

PI4K2A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.127
cellular amino acid metabolic processGO:00065201160.063
determination of adult lifespanGO:000834020.059
cellular ketone metabolic processGO:0042180800.056
multicellular organismal agingGO:001025930.053
ribonucleotide catabolic processGO:00092614050.052
vesicle mediated transportGO:00161923710.049
amine metabolic processGO:0009308440.049
regulation of cellular amino acid metabolic processGO:000652160.048
cellular macromolecule catabolic processGO:00442653800.048
regulation of cellular ketone metabolic processGO:0010565500.047
regulation of cellular amine metabolic processGO:0033238110.046
small gtpase mediated signal transductionGO:0007264780.046
ribonucleoside triphosphate metabolic processGO:00091994120.045
cellular amine metabolic processGO:0044106410.045
ribonucleoside catabolic processGO:00424544060.045
lipid metabolic processGO:00066293810.045
purine ribonucleoside metabolic processGO:00461284370.045
positive regulation of catabolic processGO:00098963100.044
defense responseGO:00069523150.044
positive regulation of cellular catabolic processGO:00313312840.044
single organism membrane organizationGO:00448022680.043
positive regulation of hydrolase activityGO:00513453310.043
regulation of protein kinase activityGO:00458592890.043
immune responseGO:00069553070.042
purine nucleoside triphosphate metabolic processGO:00091444120.042
ras protein signal transductionGO:0007265730.042
protein catabolic processGO:00301633250.041
purine ribonucleoside triphosphate metabolic processGO:00092054110.041
nucleoside catabolic processGO:00091644080.040
glycosyl compound catabolic processGO:19016584130.040
nucleoside triphosphate metabolic processGO:00091414220.040
signal transduction by phosphorylationGO:00230142970.040
purine ribonucleoside catabolic processGO:00461303980.040
regulation of transferase activityGO:00513383550.040
ribonucleoside triphosphate catabolic processGO:00092033910.039
nucleotide catabolic processGO:00091664080.039
nucleoside triphosphate catabolic processGO:00091433940.039
purine nucleotide catabolic processGO:00061954050.038
membrane organizationGO:00610242920.038
regulation of protein localizationGO:00328802960.038
purine containing compound catabolic processGO:00725234110.037
organophosphate catabolic processGO:00464344300.037
regulation of nucleotide metabolic processGO:00061402690.037
purine ribonucleotide catabolic processGO:00091544040.037
regulation of kinase activityGO:00435493140.037
transmembrane transportGO:00550853990.037
oogenesisGO:004847720.036
nucleoside phosphate catabolic processGO:19012924120.036
purine nucleoside catabolic processGO:00061523980.036
single organism cellular localizationGO:19025803320.036
negative regulation of catalytic activityGO:00430863350.035
cellular lipid metabolic processGO:00442553030.035
response to oxygen containing compoundGO:19017003690.035
female gamete generationGO:000729220.035
response to abiotic stimulusGO:00096283360.035
guanosine containing compound catabolic processGO:19010692390.034
positive regulation of cellular amine metabolic processGO:003324070.034
regulation of mapk cascadeGO:00434082620.033
positive regulation of cellular amino acid metabolic processGO:004576430.033
cytoplasmic transportGO:00164823790.033
response to cytokineGO:00340972320.033
cation transportGO:00068123310.033
negative regulation of protein metabolic processGO:00512483910.032
positive regulation of phosphorylationGO:00423273940.032
positive regulation of protein phosphorylationGO:00019343130.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
cellular protein catabolic processGO:00442572610.032
nervous system developmentGO:00073992930.032
purine nucleoside triphosphate catabolic processGO:00091463920.031
positive regulation of purine nucleotide metabolic processGO:19005442270.031
negative regulation of phosphorus metabolic processGO:00105632670.031
positive regulation of cellular component organizationGO:00511303760.031
response to biotic stimulusGO:00096072760.031
apoptotic signaling pathwayGO:00971902680.031
positive regulation of cell deathGO:00109422630.030
protein ubiquitinationGO:00165673140.030
chemical homeostasisGO:00488783060.030
cation transmembrane transportGO:00986552380.030
negative regulation of programmed cell deathGO:00430693210.030
mapk cascadeGO:00001652880.030
negative regulation of cellular protein metabolic processGO:00322693530.029
negative regulation of apoptotic processGO:00430663160.028
oxidation reduction processGO:00551143960.028
regulation of cellular component biogenesisGO:00440872810.028
negative regulation of phosphate metabolic processGO:00459362670.028
biological adhesionGO:00226103310.028
locomotory behaviorGO:000762610.028
response to external biotic stimulusGO:00432072610.027
ion transmembrane transportGO:00342203380.027
positive regulation of transportGO:00510503360.027
response to other organismGO:00517072610.027
actin filament based processGO:00300292240.027
mitotic cell cycleGO:00002783260.027
positive regulation of immune system processGO:00026842830.027
secretion by cellGO:00329402260.027
carbohydrate metabolic processGO:00059752070.027
cell adhesionGO:00071553250.027
proteolysis involved in cellular protein catabolic processGO:00516032440.027
cytokine productionGO:00018162470.027
anion transportGO:00068201610.027
positive regulation of nucleotide metabolic processGO:00459812300.026
modification dependent macromolecule catabolic processGO:00436322120.026
regulation of cellular response to stressGO:00801352440.026
negative regulation of cell deathGO:00605483450.026
regulation of purine nucleotide metabolic processGO:19005422640.026
protein modification by small protein conjugationGO:00324463420.025
cellular response to endogenous stimulusGO:00714953360.025
rho protein signal transductionGO:0007266260.025
inorganic ion transmembrane transportGO:00986602310.025
positive regulation of programmed cell deathGO:00430682490.025
single organism carbohydrate metabolic processGO:00447231930.025
cellular component morphogenesisGO:00329893140.025
secretionGO:00469032540.025
negative regulation of cell proliferationGO:00082852280.025
organonitrogen compound biosynthetic processGO:19015662000.025
small molecule biosynthetic processGO:00442831570.025
protein localization to organelleGO:00333652800.025
inorganic cation transmembrane transportGO:00986621940.024
ubiquitin dependent protein catabolic processGO:00065112060.024
reactive nitrogen species metabolic processGO:200105730.024
cellular macromolecular complex assemblyGO:00346223240.024
guanosine containing compound metabolic processGO:19010682440.024
cellular response to dna damage stimulusGO:00069743790.024
protein autophosphorylationGO:00467771230.024
negative regulation of intracellular signal transductionGO:19025321830.024
gtp metabolic processGO:00460392390.024
system processGO:00030083490.024
nitrogen compound transportGO:00717051910.024
regulation of protein serine threonine kinase activityGO:00719001790.023
positive regulation of transferase activityGO:00513472270.023
carbohydrate derivative biosynthetic processGO:19011372070.023
organic anion transportGO:00157111030.023
positive regulation of nucleoside metabolic processGO:00459791860.023
protein maturationGO:00516042330.023
cellular response to oxygen containing compoundGO:19017012760.023
reactive oxygen species biosynthetic processGO:190340940.023
regulation of proteolysisGO:00301622930.023
positive regulation of apoptotic processGO:00430652460.023
dephosphorylationGO:00163112090.023
cell morphogenesisGO:00009022960.023
regulation of establishment of protein localizationGO:00702012420.022
ion homeostasisGO:00508012300.022
modification dependent protein catabolic processGO:00199412090.022
positive regulation of protein kinase activityGO:00458601900.022
positive regulation of kinase activityGO:00336742040.022
endomembrane system organizationGO:00102561960.022
organophosphate biosynthetic processGO:00904071630.022
regulation of cell migrationGO:00303342890.022
memoryGO:000761330.022
neuromuscular junction developmentGO:000752830.022
regulation of response to external stimulusGO:00321012220.022
maintenance of locationGO:00512351120.022
regenerationGO:003109940.022
regulation of cytokine productionGO:00018172320.022
regulation of nucleotide catabolic processGO:00308112050.022
organic hydroxy compound metabolic processGO:19016151470.021
innate immune responseGO:00450871780.021
negative regulation of cellular component organizationGO:00511292350.021
regulation of cell differentiationGO:00455953930.021
cell projection organizationGO:00300302520.021
regulation of cell motilityGO:20001452990.021
metal ion transportGO:00300012720.021
regulation of protein transportGO:00512232130.021
segmentationGO:003528240.021
endosomal transportGO:00161971290.021
alcohol metabolic processGO:00060661140.021
negative regulation of phosphorylationGO:00423261740.021
regulation of locomotionGO:00400123290.020
regulation of gtpase activityGO:00430871800.020
gtp catabolic processGO:00061842370.020
regulation of nucleoside metabolic processGO:00091182090.020
positive regulation of gtp catabolic processGO:00331261660.020
regulation of protein catabolic processGO:00421761550.020
protein processingGO:00164852260.020
regulation of cellular component movementGO:00512703340.019
regulation of purine nucleotide catabolic processGO:00331212050.019
regulation of anatomical structure morphogenesisGO:00226032860.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
positive regulation of nucleotide catabolic processGO:00308131850.019
regulation of secretionGO:00510461940.019
cellular response to growth factor stimulusGO:00713631970.019
regulation of immune responseGO:00507762010.019
interspecies interaction between organismsGO:00444191560.019
intracellular protein transportGO:00068862700.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
glycerolipid metabolic processGO:00464861070.019
lipid localizationGO:00108761060.019
negative regulation of cellular amine metabolic processGO:003323930.019
lipid biosynthetic processGO:00086101770.019
mitotic cell cycle processGO:19030472860.019
cell developmentGO:00484683280.019
response to lipidGO:00339932060.019
negative regulation of multicellular organismal processGO:00512413170.019
proteasomal protein catabolic processGO:00104981760.018
negative regulation of protein modification processGO:00314002000.018
endocytosisGO:00068971590.018
cellular response to external stimulusGO:00714961110.018
reactive oxygen species metabolic processGO:0072593750.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
monocarboxylic acid metabolic processGO:00327871850.018
response to nitrogen compoundGO:19016981840.018
regulation of multi organism processGO:00439001570.018
positive regulation of cell proliferationGO:00082843010.018
rhythmic behaviorGO:000762220.018
regulation of secretion by cellGO:19035301770.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
regulation of gtp catabolic processGO:00331241800.018
posttranscriptional regulation of gene expressionGO:00106082130.018
protein oligomerizationGO:00512591730.017
cellular response to organic cyclic compoundGO:00714071270.017
cellular protein complex assemblyGO:00436231880.017
actin cytoskeleton organizationGO:00300362070.017
protein targetingGO:00066051870.017
organelle assemblyGO:00709251760.017
purine nucleoside monophosphate metabolic processGO:00091261860.017
regulation of apoptotic signaling pathwayGO:20012331750.017
regulation of cell cycle processGO:00105642660.017
neurotransmitter secretionGO:000726940.017
regulation of intracellular transportGO:00323861950.017
defense response to other organismGO:00985421290.017
adult locomotory behaviorGO:000834410.017
multi organism cellular processGO:00447641560.017
negative regulation of protein phosphorylationGO:00019331400.017
protein localization to membraneGO:00726571600.017
spermatid developmentGO:000728640.017
growthGO:00400072020.016
response to hormoneGO:00097251750.016
circadian behaviorGO:004851220.016
cell growthGO:00160491600.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
regulation of synaptic plasticityGO:004816730.016
microtubule cytoskeleton organizationGO:00002261760.016
response to fungusGO:000962040.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
hemopoiesisGO:00300971800.016
cell activationGO:00017752130.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
blastoderm segmentationGO:000735020.016
regulation of defense responseGO:00313471540.016
response to axon injuryGO:004867810.016
atp metabolic processGO:00460341760.016
regulation of growthGO:00400081650.016
positive regulation of synaptic transmissionGO:005080640.016
positive regulation of gtpase activityGO:00435471660.016
negative regulation of transportGO:00510511760.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
response to growth factorGO:00708482050.016
spermatid differentiationGO:004851540.016
cellular chemical homeostasisGO:00550821800.016
response to bacteriumGO:00096171440.016
negative regulation of transferase activityGO:00513481240.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
oocyte developmentGO:004859910.015
oocyte differentiationGO:000999420.015
covalent chromatin modificationGO:00165692540.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
hindbrain developmentGO:003090230.015
meiotic chromosome segregationGO:004513240.015
regulation of ras protein signal transductionGO:00465781550.015
positive regulation of cell migrationGO:00303351720.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
establishment of protein localization to membraneGO:00901501210.015
chromatin organizationGO:00063253510.015
response to virusGO:00096151260.015
response to inorganic substanceGO:00100351270.015
regulation of cell cycleGO:00517263930.015
response to organic cyclic compoundGO:00140702040.015
i kappab kinase nf kappab signalingGO:00072491660.015
regulation of hormone levelsGO:00108171250.015
organelle fissionGO:00482851490.015
regulation of vesicle mediated transportGO:00606271300.015
regulation of cytoskeleton organizationGO:00514931770.015
negative regulation of kinase activityGO:00336731060.015
wnt signaling pathwayGO:00160551560.015
negative regulation of hydrolase activityGO:00513461820.015
purine containing compound biosynthetic processGO:0072522880.015
positive regulation of immune responseGO:00507781590.015
establishment of protein localization to organelleGO:00725941720.015
histone modificationGO:00165702510.014
phospholipid metabolic processGO:0006644990.014
nucleoside monophosphate metabolic processGO:00091231910.014
epithelial cell differentiationGO:00308551410.014
carboxylic acid biosynthetic processGO:0046394970.014
response to organonitrogen compoundGO:00102431560.014
cellular homeostasisGO:00197251960.014
motor neuron axon guidanceGO:000804520.014
positive regulation of organelle organizationGO:00106381950.014
regulation of protein maturationGO:19033171500.014
regulation of protein complex assemblyGO:00432541470.014
organic acid biosynthetic processGO:0016053970.014
small molecule catabolic processGO:0044282920.014
monovalent inorganic cation transportGO:00156721280.014
peripheral nervous system developmentGO:000742220.014
cellular response to abiotic stimulusGO:00712141170.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
chromatin modificationGO:00165682980.014
generation of neuronsGO:00486991520.014
anterior posterior axis specificationGO:000994820.014
regulation of anatomical structure sizeGO:00900661010.014
dna repairGO:00062811980.014
activation of immune responseGO:00022531140.014
cardiac muscle cell contractionGO:008600340.014
autophagyGO:0006914880.014
negative regulation of protein kinase activityGO:0006469980.014
immune effector processGO:00022521590.014
response to oxidative stressGO:00069791210.014
regulation of neurotransmitter secretionGO:004692830.014
positive regulation of secretion by cellGO:19035321080.014
compound eye developmentGO:004874910.013
cofactor metabolic processGO:0051186870.013
lipid catabolic processGO:0016042840.013
response to woundingGO:00096111680.013
metencephalon developmentGO:002203720.013
negative regulation of developmental processGO:00510932470.013
establishment of nucleus localizationGO:004002310.013
regulation of stress activated protein kinase signaling cascadeGO:0070302850.013
positive regulation of cell motilityGO:20001471770.013
organic hydroxy compound biosynthetic processGO:1901617710.013
regulation of mitotic cell cycleGO:00073461890.013
nucleus localizationGO:005164710.013
viral processGO:00160321460.013
cell part morphogenesisGO:00329901370.013
nuclear transportGO:00511691790.013
multicellular organismal response to stressGO:003355510.013
protein acylationGO:00435431380.013
immune system developmentGO:00025201950.013
nucleotide biosynthetic processGO:00091651090.013
immune response activating signal transductionGO:0002757900.013
immune response regulating signaling pathwayGO:0002764970.013
cation homeostasisGO:00550801890.013
negative regulation of organelle organizationGO:00106391260.013
positive regulation of proteolysisGO:00458621420.013
cell cycle phase transitionGO:00447701730.013
regulation of ras gtpase activityGO:00323181280.013
steroid metabolic processGO:0008202940.013
regulation of peptidase activityGO:00525471800.013
neurogenesisGO:00220081690.013
epithelium developmentGO:00604292270.013
positive regulation of secretionGO:00510471160.013
nucleocytoplasmic transportGO:00069131760.013
neuron differentiationGO:00301821380.013
jnk cascadeGO:0007254800.013
organ formationGO:004864530.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
protein homooligomerizationGO:00512601000.013
glycerophospholipid metabolic processGO:0006650840.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
regulation of endopeptidase activityGO:00525481700.013
positive regulation of mapk cascadeGO:00434101900.013
positive regulation of developmental processGO:00510943140.013
cellular response to nitrogen compoundGO:19016991440.013
plasma membrane organizationGO:00070091150.013
microtubule based processGO:00070172100.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
regulation of stress activated mapk cascadeGO:0032872840.013
cellular response to lipidGO:00713961270.013
leukocyte activationGO:00453211640.012
negative regulation of proteolysisGO:00458611320.012
golgi vesicle transportGO:0048193800.012
stress activated protein kinase signaling cascadeGO:0031098940.012
nuclear migrationGO:000709710.012
syncytium formation by plasma membrane fusionGO:000076820.012
fatty acid metabolic processGO:00066311150.012
vacuole organizationGO:0007033440.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
protein secretionGO:0009306980.012
regulation of intracellular protein transportGO:00331571230.012
anterior posterior axis specification embryoGO:000859520.012
vasodilationGO:004231140.012
photoreceptor cell differentiationGO:004653020.012
mitochondrion organizationGO:00070051560.012
anatomical structure formation involved in morphogenesisGO:00486462840.012
positive regulation of protein transportGO:00512221350.012
sequestering of metal ionGO:0051238240.012
regulation of cytoplasmic transportGO:19036491490.012
sensory perception of smellGO:000760820.012
limbic system developmentGO:002176130.012
cellular cation homeostasisGO:00300031630.012
tripartite regional subdivisionGO:000735120.012
meiosis iGO:000712740.012
nuclear divisionGO:00002801280.012
regulation of cell morphogenesisGO:00226041530.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
inner ear morphogenesisGO:004247240.012
regulation of ion transportGO:00432691890.012
neurological system processGO:00508771630.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
actin filament organizationGO:00070151280.012
regulation of cell developmentGO:00602841610.012
negative regulation of cell cycleGO:00457861930.012
regulation of map kinase activityGO:00434051080.012
peptidyl tyrosine modificationGO:00182121700.012
reproductive processGO:00224141060.012
cell divisionGO:00513011680.012
regulation of jnk cascadeGO:0046328730.012
regulation of protein processingGO:00706131500.012
regulation of cell growthGO:00015581350.012
cell cell signalingGO:00072671550.012
nucleoside monophosphate catabolic processGO:00091251590.012
regulation of cellular protein catabolic processGO:1903362960.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
cellular response to nutrient levelsGO:0031669690.012
cellular ion homeostasisGO:00068731680.012
positive regulation of ras gtpase activityGO:00323201170.012
cellular response to organonitrogen compoundGO:00714171240.012
positive regulation of cell differentiationGO:00455972110.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of dephosphorylationGO:0035303960.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
stress activated mapk cascadeGO:0051403930.012
sulfur compound metabolic processGO:00067901010.012
positive regulation of locomotionGO:00400171860.011
regulation of meiotic cell cycleGO:005144540.011
defense response to fungusGO:005083240.011
sensory perception of painGO:001923340.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
monocarboxylic acid biosynthetic processGO:0072330670.011
protein localization to nucleusGO:00345041360.011
cell fate determinationGO:000170930.011
response to hypoxiaGO:0001666960.011
cerebellum developmentGO:002154920.011
positive regulation of protein catabolic processGO:0045732750.011
regulation of cell adhesionGO:00301551660.011
regulation of proteasomal protein catabolic processGO:0061136870.011
regulation of innate immune responseGO:0045088970.011
rna interferenceGO:001624640.011
negative regulation of cell migrationGO:00303361020.011
inflammatory responseGO:0006954790.011
divalent metal ion transportGO:00708381520.011
positive regulation of intracellular transportGO:00323881040.011
ribose phosphate biosynthetic processGO:0046390820.011
metal ion homeostasisGO:00550651690.011
glycoprotein metabolic processGO:00091001100.011
cell projection assemblyGO:00300311260.011
purine nucleotide biosynthetic processGO:0006164840.011
myoblast fusionGO:000752010.011
visual behaviorGO:000763220.011
gastrulation with mouth forming secondGO:000170210.011
tissue regenerationGO:004224630.011
negative regulation of protein processingGO:00109551420.011
associative learningGO:000830610.011
regulation of bindingGO:00510981110.011
mitotic nuclear divisionGO:00070671190.011
cellular response to extracellular stimulusGO:0031668720.011
mitotic cell cycle phase transitionGO:00447721620.011
actin mediated cell contractionGO:0070252120.011
negative regulation of protein maturationGO:19033181420.011
single organism reproductive processGO:0044702980.011
atp catabolic processGO:00062001570.011
myosin filament assemblyGO:003103420.011
actin filament based movementGO:0030048170.011
lipid transportGO:0006869900.011
epithelium migrationGO:00901321190.011
viral life cycleGO:00190581320.011
negative regulation of immune system processGO:00026831360.011
axon cargo transportGO:000808820.011
response to oxygen levelsGO:00704821000.011
neuroblast proliferationGO:000740540.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.011
regulation of membrane potentialGO:0042391950.011
positive regulation of cellular component movementGO:00512721810.011
morphogenesis of embryonic epitheliumGO:001633140.011
activation of protein kinase activityGO:0032147900.010
sleepGO:003043120.010
nucleoside phosphate biosynthetic processGO:19012931090.010
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.010

PI4K2A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.049
inherited metabolic disorderDOID:6552420.047
central nervous system diseaseDOID:3311860.035
nervous system diseaseDOID:8634310.035
musculoskeletal system diseaseDOID:172230.028
sensory system diseaseDOID:00501552030.019
connective tissue diseaseDOID:651090.018
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
bone diseaseDOID:0080001880.017
cardiovascular system diseaseDOID:12871060.017
immune system diseaseDOID:29141550.016
neurodegenerative diseaseDOID:12891020.015
disease of mental healthDOID:150700.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.013
lysosomal storage diseaseDOID:3211470.013
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
myopathyDOID:4231040.012
retinal diseaseDOID:56791180.012
brain diseaseDOID:936730.011