Homo sapiens

19 known processes

HLA-C

major histocompatibility complex, class I, C

(Aliases: HLA-Cw,FLJ27082,HLA-JY3,PSORS1,D6S204,HLC-C)

HLA-C biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulus involved in sensory perceptionGO:0050907331.000
Human
antigen processing and presentation via mhc class ibGO:000247531.000
Human
immune response inhibiting cell surface receptor signaling pathwayGO:000276741.000
Human
regulation of regulatory t cell differentiationGO:004558941.000
Human
detection of external biotic stimulusGO:0098581191.000
Human
positive regulation of natural killer cell mediated immunityGO:0002717121.000
Human
sensory perception of chemical stimulusGO:0007606381.000
Human
positive regulation of regulatory t cell differentiationGO:004559131.000
Human
sensory perception of bitter tasteGO:0050913281.000
Human
regulation of natural killer cell mediated cytotoxicityGO:0042269161.000
Human
regulation of dendritic cell differentiationGO:200119831.000
Human
positive regulation of t cell tolerance inductionGO:000266621.000
Human
dendritic cell differentiationGO:0097028131.000
Human
sensory perception of tasteGO:0050909361.000
Human
detection of biotic stimulusGO:0009595211.000
Human
detection of other organismGO:0098543131.000
Human
antigen processing and presentation of endogenous antigenGO:001988371.000
detection of chemical stimulusGO:0009593551.000
Human
negative regulation of t cell proliferationGO:004213081.000
Human
regulation of natural killer cell mediated immunityGO:0002715161.000
Human
negative regulation of natural killer cell mediated cytotoxicityGO:004595350.999
Human
negative regulation of leukocyte mediated immunityGO:0002704140.999
Human
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.999
Human
positive regulation of lymphocyte differentiationGO:0045621130.998
Human
immune response inhibiting signal transductionGO:000276540.998
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.998
retina homeostasisGO:0001895420.997
Human
negative regulation of leukocyte differentiationGO:1902106240.996
Human
transition metal ion transportGO:0000041230.995
Human
natural killer cell mediated immunityGO:0002228230.995
Human
positive regulation of tolerance inductionGO:000264520.994
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independentGO:000248630.992
t cell tolerance inductionGO:000251740.992
Human
tolerance inductionGO:000250760.992
Human
antigen processing and presentation of peptide antigen via mhc class ibGO:000242820.991
Human
detection of stimulusGO:0051606850.989
Human
iron ion import into cellGO:009745920.989
Human
negative regulation of cell proliferationGO:00082852280.986
Human
response to other organismGO:00517072610.984
Human
cell killingGO:0001906340.978
Human
regulation of cell killingGO:0031341220.975
Human
antigen processing and presentationGO:0019882330.973
negative regulation of lymphocyte mediated immunityGO:0002707120.973
Human
t cell mediated cytotoxicityGO:000191390.970
Human
adaptive immune responseGO:0002250490.969
Human
memory t cell activationGO:003570910.967
Human
positive regulation of leukocyte mediated immunityGO:0002705240.966
Human
negative regulation of leukocyte activationGO:0002695260.964
Human
antigen processing and presentation of peptide antigenGO:0048002180.963
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.961
Human
detection of bacteriumGO:0016045130.961
Human
regulation of t cell mediated cytotoxicityGO:000191480.961
Human
regulation of memory t cell activationGO:200056710.961
Human
negative regulation of cell killingGO:003134250.958
Human
tissue homeostasisGO:0001894630.957
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.956
Human
inorganic cation import into cellGO:009865920.951
Human
response to biotic stimulusGO:00096072760.942
Human
positive regulation of memory t cell activationGO:200056810.936
Human
positive regulation of cell killingGO:0031343190.936
Human
antigen processing and presentation of peptide antigen via mhc class iGO:000247460.936
positive regulation of t cell mediated immunityGO:0002711120.936
Human
regulation of leukocyte differentiationGO:1902105610.927
Human
regulation of leukocyte mediated immunityGO:0002703380.921
Human
positive regulation of lymphocyte mediated immunityGO:0002708230.919
Human
regulation of lymphocyte mediated immunityGO:0002706330.917
Human
immune effector processGO:00022521590.914
Human
regulation of tolerance inductionGO:000264340.909
Human
import into cellGO:009865720.909
Human
cation transportGO:00068123310.908
Human
lymphocyte mediated immunityGO:0002449480.906
Human
negative regulation of defense responseGO:0031348470.904
Human
regulation of t cell activationGO:0050863770.904
Human
response to bacteriumGO:00096171440.902
Human
regulation of leukocyte mediated cytotoxicityGO:0001910190.901
Human
innate immune responseGO:00450871780.900
Human
regulation of t cell mediated immunityGO:0002709180.897
Human
negative regulation of leukocyte mediated cytotoxicityGO:000191150.896
Human
response to external biotic stimulusGO:00432072610.894
Human
multicellular organismal homeostasisGO:0048871670.890
Human
regulation of innate immune responseGO:0045088970.885
Human
regulation of cytokine productionGO:00018172320.876
Human
regulation of adaptive immune responseGO:0002819330.876
Human
regulation of t cell tolerance inductionGO:000266440.872
Human
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.867
Human
leukocyte mediated cytotoxicityGO:0001909270.864
Human
positive regulation of cytokine productionGO:00018191670.863
Human
regulation of immune responseGO:00507762010.863
Human
positive regulation of interleukin 12 productionGO:003273580.860
Human
immune system developmentGO:00025201950.859
Human
antigen processing and presentation of endogenous peptide antigenGO:000248360.854
interleukin 12 productionGO:0032615150.854
Human
negative regulation of dendritic cell differentiationGO:200119920.853
Human
positive regulation of leukocyte differentiationGO:1902107370.851
Human
type i interferon signaling pathwayGO:0060337110.843
cytokine productionGO:00018162470.842
Human
negative regulation of immune system processGO:00026831360.839
Human
defense responseGO:00069523150.824
Human
leukocyte differentiationGO:0002521980.818
Human
natural killer cell mediated cytotoxicityGO:0042267230.816
Human
positive regulation of immune responseGO:00507781590.807
Human
immune response regulating signaling pathwayGO:0002764970.807
Human
negative regulation of immune responseGO:0050777400.799
Human
inorganic ion import into cellGO:009958720.796
Human
leukocyte mediated immunityGO:0002443590.789
Human
hemopoiesisGO:00300971800.787
Human
negative regulation of multicellular organismal processGO:00512413170.764
Human
regulation of immune effector processGO:0002697910.761
Human
lymphocyte proliferationGO:0046651700.760
Human
negative regulation of innate immune responseGO:0045824180.753
Human
positive regulation of defense responseGO:0031349870.744
Human
positive regulation of interferon gamma productionGO:0032729260.742
Human
negative regulation of immune effector processGO:0002698380.740
Human
positive regulation of innate immune responseGO:0045089790.730
Human
positive regulation of developmental processGO:00510943140.728
Human
leukocyte activationGO:00453211640.709
Human
positive regulation of immune system processGO:00026842830.709
Human
regulation of leukocyte proliferationGO:0070663670.705
Human
positive regulation of leukocyte activationGO:0002696800.704
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.666
Human
positive regulation of cell differentiationGO:00455972110.658
Human
regulation of defense responseGO:00313471540.657
Human
regulation of cell activationGO:00508651250.646
Human
hematopoietic or lymphoid organ developmentGO:00485341860.631
Human
iron ion transportGO:0006826120.631
Human
positive regulation of immune effector processGO:0002699400.617
Human
cell activationGO:00017752130.606
Human
immune responseGO:00069553070.601
Human
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988550.598
positive regulation of adaptive immune responseGO:0002821210.595
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.594
protection from natural killer cell mediated cytotoxicityGO:004227030.591
Human
anatomical structure homeostasisGO:00602491000.565
Human
regulation of cell differentiationGO:00455953930.556
Human
negative regulation of leukocyte proliferationGO:0070664160.553
Human
system processGO:00030083490.543
Human
regulation of leukocyte activationGO:00026941150.543
Human
leukocyte proliferationGO:0070661740.513
Human
mononuclear cell proliferationGO:0032943710.504
Human
detection of stimulus involved in sensory perceptionGO:0050906430.480
Human
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247620.478
Human
regulation of interferon gamma productionGO:0032649360.476
Human
neurological system processGO:00508771630.444
Human
regulation of mononuclear cell proliferationGO:0032944650.443
Human
interferon gamma productionGO:0032609390.433
Human
positive regulation of t cell mediated cytotoxicityGO:000191670.418
Human
t cell mediated immunityGO:0002456250.417
Human
negative regulation of developmental processGO:00510932470.401
Human
positive regulation of t cell differentiationGO:0045582110.392
Human
t cell activationGO:0042110990.370
Human
regulation of interleukin 12 productionGO:0032655150.366
Human
negative regulation of cell differentiationGO:00455961710.363
Human
lymphocyte differentiationGO:0030098350.355
Human
positive regulation of cell activationGO:0050867810.335
Human
regulation of lymphocyte proliferationGO:0050670640.318
Human
positive regulation of t cell activationGO:0050870540.305
Human
lymphocyte activationGO:00466491330.266
Human
cell adhesionGO:00071553250.241
Human
regulation of t cell proliferationGO:0042129420.232
Human
negative regulation of cell activationGO:0050866330.203
Human
sensory perceptionGO:00076001030.203
Human
immune response regulating cell surface receptor signaling pathwayGO:0002768510.198
Human
regulation of lymphocyte activationGO:00512491030.190
Human
regulation of t cell differentiationGO:0045580190.184
Human
interleukin 6 productionGO:0032635370.166
detection of chemical stimulus involved in sensory perception of bitter tasteGO:0001580280.136
Human
t cell differentiationGO:0030217290.135
Human
regulation of lymphocyte differentiationGO:0045619220.133
Human
astrocyte chemotaxisGO:003570010.118
negative regulation of cellular protein metabolic processGO:00322693530.115
post embryonic developmentGO:000979120.106
metal ion transportGO:00300012720.105
Human
negative regulation of multi organism processGO:0043901920.103
biological adhesionGO:00226103310.103
Human
t cell differentiation in thymusGO:003307740.096
purine ribonucleoside triphosphate catabolic processGO:00092073910.089
response to interferon gammaGO:0034341390.079
negative regulation of lymphocyte proliferationGO:0050672150.076
Human
response to type i interferonGO:0034340140.073
detection of muramyl dipeptideGO:003249810.065
negative regulation of lymphocyte activationGO:0051250240.063
Human
mapk cascadeGO:00001652880.063
regulation of calcium ion transportGO:0051924790.062
cell projection organizationGO:00300302520.059
cellular response to oxidative stressGO:0034599850.055
cytoplasmic transportGO:00164823790.055
intracellular protein transportGO:00068862700.047
negative regulation of phosphorylationGO:00423261740.046
chemical homeostasisGO:00488783060.046
ribonucleoside triphosphate catabolic processGO:00092033910.045
negative regulation of t cell activationGO:0050868180.045
Human
purine containing compound catabolic processGO:00725234110.044
t cell proliferationGO:0042098450.044
Human
iron ion homeostasisGO:0055072150.043
cytokine production involved in immune responseGO:0002367270.043
positive regulation of interleukin 13 productionGO:003273640.043
negative regulation of protein metabolic processGO:00512483910.043
ossificationGO:00015031210.041
negative regulation of mononuclear cell proliferationGO:0032945150.040
Human
negative regulation of natural killer cell mediated immunityGO:000271650.039
Human
nucleoside catabolic processGO:00091644080.039
interaction with hostGO:0051701420.038
protein maturationGO:00516042330.037
purine ribonucleoside metabolic processGO:00461284370.037
motor neuron axon guidanceGO:000804520.035
regulatory t cell differentiationGO:004506650.034
Human
multicellular organismal agingGO:001025930.033
purine nucleoside monophosphate metabolic processGO:00091261860.033
positive regulation of purine nucleotide metabolic processGO:19005442270.033
cellular amine metabolic processGO:0044106410.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.031
tissue regenerationGO:004224630.029
ribonucleoside monophosphate metabolic processGO:00091611870.029
atp catabolic processGO:00062001570.028
negative regulation of transportGO:00510511760.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
regulation of cellular ketone metabolic processGO:0010565500.026
cellular response to type i interferonGO:0071357120.025
ribonucleotide catabolic processGO:00092614050.025
proteolysis involved in cellular protein catabolic processGO:00516032440.025
protein ubiquitinationGO:00165673140.025
divalent inorganic cation transportGO:00725111580.025
entry into host cellGO:0030260250.024
regulation of mast cell chemotaxisGO:006075340.023
negative regulation of cell deathGO:00605483450.023
ribonucleoside monophosphate catabolic processGO:00091581580.023
secretion by cellGO:00329402260.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
cell growthGO:00160491600.022
negative regulation of phosphorus metabolic processGO:00105632670.022
negative regulation of catalytic activityGO:00430863350.021
regulation of viral transcriptionGO:0046782340.021
regulation of cellular amino acid metabolic processGO:000652160.021
positive regulation of cellular amine metabolic processGO:003324070.021
secretionGO:00469032540.021
regulation of cell migrationGO:00303342890.021
defense response to other organismGO:00985421290.021
inflammatory responseGO:0006954790.021
ion homeostasisGO:00508012300.021
negative regulation of intracellular signal transductionGO:19025321830.020
cellular macromolecule catabolic processGO:00442653800.020
lipid metabolic processGO:00066293810.019
cation homeostasisGO:00550801890.019
cellular ketone metabolic processGO:0042180800.019
cellular response to lipidGO:00713961270.018
maintenance of locationGO:00512351120.018
regulation of secretionGO:00510461940.018
detection of peptidoglycanGO:003249910.018
cellular response to cytokine stimulusGO:00713451810.018
heart contractionGO:0060047620.018
glycoprotein metabolic processGO:00091001100.018
regulation of cell cycleGO:00517263930.017
growthGO:00400072020.017
nucleoside monophosphate metabolic processGO:00091231910.017
nucleoside monophosphate catabolic processGO:00091251590.017
regulation of ligase activityGO:0051340290.017
negative regulation of protein modification processGO:00314002000.016
positive regulation of cell deathGO:00109422630.016
movement in environment of other organism involved in symbiotic interactionGO:0052192250.016
rna catabolic processGO:0006401710.016
signal transduction by phosphorylationGO:00230142970.016
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108110.016
nucleoside triphosphate catabolic processGO:00091433940.015
regulation of proteolysisGO:00301622930.015
epithelial cell differentiationGO:00308551410.015
cellular protein catabolic processGO:00442572610.015
purine nucleotide catabolic processGO:00061954050.015
regulation of intracellular transportGO:00323861950.015
response to thyroid hormoneGO:009706690.014
regulation of nucleotide metabolic processGO:00061402690.014
purine ribonucleotide catabolic processGO:00091544040.014
determination of adult lifespanGO:000834020.014
regulation of cellular amine metabolic processGO:0033238110.014
positive regulation of cell proliferationGO:00082843010.014
purine nucleoside monophosphate catabolic processGO:00091281580.013
negative regulation of peptidase activityGO:0010466910.013
response to inorganic substanceGO:00100351270.013
atp metabolic processGO:00460341760.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
immune response activating signal transductionGO:0002757900.013
negative regulation of programmed cell deathGO:00430693210.013
organophosphate catabolic processGO:00464344300.012
osteoblast differentiationGO:0001649920.012
defense response to virusGO:0051607710.012
negative regulation of cell motilityGO:20001461040.012
single organism membrane organizationGO:00448022680.012
proteasomal protein catabolic processGO:00104981760.012
nucleoside triphosphate metabolic processGO:00091414220.012
negative regulation of phosphate metabolic processGO:00459362670.012
entry into hostGO:0044409250.012
regulation of angiogenesisGO:0045765920.012
regulation of protein maturationGO:19033171500.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
epithelium developmentGO:00604292270.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
mitotic cell cycle processGO:19030472860.011
regulation of cell motilityGO:20001452990.011
pattern recognition receptor signaling pathwayGO:0002221480.011
negative regulation of protein phosphorylationGO:00019331400.011
regulation of purine nucleotide metabolic processGO:19005422640.011
regulation of homeostatic processGO:00328441210.011
cellular homeostasisGO:00197251960.011
positive regulation of purine nucleotide biosynthetic processGO:1900373380.011
negative regulation of viral processGO:0048525660.011
negative regulation of response to external stimulusGO:0032102830.011
regulation of establishment of protein localizationGO:00702012420.011
regulation of membrane potentialGO:0042391950.010
single organism reproductive processGO:0044702980.010
multi organism metabolic processGO:0044033410.010
blastoderm segmentationGO:000735020.010
negative regulation of apoptotic processGO:00430663160.010
amine metabolic processGO:0009308440.010
regulation of protein localizationGO:00328802960.010
regulation of complement activation lectin pathwayGO:000186820.010
nucleotide catabolic processGO:00091664080.010
cellular response to oxygen containing compoundGO:19017012760.010
regulation of camp metabolic processGO:0030814520.010
circulatory system developmentGO:00723592620.010
negative regulation of cellular component organizationGO:00511292350.010

HLA-C disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.828
disease of metabolismDOID:00146672950.547
Human
inherited metabolic disorderDOID:6552420.196
Human
neuronal ceroid lipofuscinosisDOID:14503110.100
lipid storage diseaseDOID:9455280.100
lysosomal storage diseaseDOID:3211470.100
connective tissue diseaseDOID:651090.076
bone diseaseDOID:0080001880.076
primary immunodeficiency diseaseDOID:612360.040
severe combined immunodeficiencyDOID:627100.040
immune system diseaseDOID:29141550.040
combined t cell and b cell immunodeficiencyDOID:628120.040
artery diseaseDOID:0050828230.022
vascular diseaseDOID:178250.022
cardiovascular system diseaseDOID:12871060.022
central nervous system diseaseDOID:3311860.011
Human
nervous system diseaseDOID:8634310.011
Human
sensory system diseaseDOID:00501552030.010
disease by infectious agentDOID:0050117340.002
integumentary system diseaseDOID:16430.001
skin diseaseDOID:37330.000
psoriasisDOID:889340.000
viral infectious diseaseDOID:934130.000
human immunodeficiency virus infectious diseaseDOID:526130.000
acquired immunodeficiency syndromeDOID:635130.000