Homo sapiens

130 known processes

HLA-B

major histocompatibility complex, class I, B

(Aliases: SPDA1,Bw-48,HLA-B27,HLA-B73,HLAB,AS,HLA-B-5601,MGC111087,Bw-45,HLA-B-6701,Bw-56)

HLA-B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulus involved in sensory perceptionGO:0050907331.000
antigen processing and presentation via mhc class ibGO:000247531.000
immune response inhibiting cell surface receptor signaling pathwayGO:000276741.000
regulation of dendritic cell differentiationGO:200119831.000
sensory perception of tasteGO:0050909361.000
detection of chemical stimulusGO:0009593551.000
detection of external biotic stimulusGO:0098581191.000
positive regulation of regulatory t cell differentiationGO:004559131.000
regulation of natural killer cell mediated cytotoxicityGO:0042269161.000
positive regulation of natural killer cell mediated immunityGO:0002717121.000
positive regulation of t cell tolerance inductionGO:000266621.000
regulation of regulatory t cell differentiationGO:004558941.000
dendritic cell differentiationGO:0097028131.000
sensory perception of chemical stimulusGO:0007606381.000
retina homeostasisGO:0001895421.000
detection of biotic stimulusGO:0009595211.000
sensory perception of bitter tasteGO:0050913281.000
negative regulation of dendritic cell differentiationGO:200119920.999
negative regulation of leukocyte mediated cytotoxicityGO:000191150.999
negative regulation of t cell proliferationGO:004213080.998
immune response inhibiting signal transductionGO:000276540.998
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.997
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.997
detection of stimulusGO:0051606850.997
t cell tolerance inductionGO:000251740.996
positive regulation of lymphocyte differentiationGO:0045621130.995
antigen processing and presentation of peptide antigenGO:0048002180.994
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independentGO:000248630.991
detection of other organismGO:0098543130.989
iron ion import into cellGO:009745920.988
transition metal ion transportGO:0000041230.988
negative regulation of natural killer cell mediated cytotoxicityGO:004595350.987
antigen processing and presentation of endogenous antigenGO:001988370.984
detection of stimulus involved in sensory perceptionGO:0050906430.983
antigen processing and presentation of peptide antigen via mhc class iGO:000247460.980
negative regulation of leukocyte mediated immunityGO:0002704140.980
negative regulation of cell proliferationGO:00082852280.980
antigen processing and presentationGO:0019882330.977
regulation of cell killingGO:0031341220.975
negative regulation of leukocyte differentiationGO:1902106240.974
antigen processing and presentation of peptide antigen via mhc class ibGO:000242820.960
positive regulation of interleukin 12 productionGO:003273580.950
negative regulation of leukocyte activationGO:0002695260.949
regulation of t cell mediated immunityGO:0002709180.948
regulation of t cell tolerance inductionGO:000266440.944
positive regulation of defense responseGO:0031349870.937
positive regulation of cytokine productionGO:00018191670.935
cytokine productionGO:00018162470.929
hematopoietic or lymphoid organ developmentGO:00485341860.927
regulation of leukocyte proliferationGO:0070663670.927
regulation of leukocyte differentiationGO:1902105610.926
regulation of t cell mediated cytotoxicityGO:000191480.924
negative regulation of innate immune responseGO:0045824180.923
regulation of t cell activationGO:0050863770.917
lymphocyte proliferationGO:0046651700.916
natural killer cell mediated cytotoxicityGO:0042267230.913
positive regulation of interferon gamma productionGO:0032729260.909
inorganic cation import into cellGO:009865920.909
negative regulation of t cell activationGO:0050868180.908
cell adhesionGO:00071553250.907
cation transportGO:00068123310.906
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.904
detection of bacteriumGO:0016045130.903
regulation of leukocyte mediated immunityGO:0002703380.895
interferon gamma productionGO:0032609390.890
t cell mediated cytotoxicityGO:000191390.889
cell killingGO:0001906340.888
regulation of cytokine productionGO:00018172320.885
multicellular organismal homeostasisGO:0048871670.881
mononuclear cell proliferationGO:0032943710.880
interleukin 12 productionGO:0032615150.872
tissue homeostasisGO:0001894630.870
negative regulation of defense responseGO:0031348470.869
positive regulation of memory t cell activationGO:200056810.865
import into cellGO:009865720.864
protection from natural killer cell mediated cytotoxicityGO:004227030.861
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988550.858
negative regulation of cell differentiationGO:00455961710.850
positive regulation of adaptive immune responseGO:0002821210.845
defense responseGO:00069523150.844
positive regulation of innate immune responseGO:0045089790.841
positive regulation of t cell mediated immunityGO:0002711120.831
tolerance inductionGO:000250760.828
regulation of t cell proliferationGO:0042129420.826
regulation of natural killer cell mediated immunityGO:0002715160.825
t cell mediated immunityGO:0002456250.818
negative regulation of lymphocyte mediated immunityGO:0002707120.815
innate immune responseGO:00450871780.812
natural killer cell mediated immunityGO:0002228230.812
immune response regulating signaling pathwayGO:0002764970.807
metal ion transportGO:00300012720.806
regulation of mononuclear cell proliferationGO:0032944650.803
positive regulation of leukocyte activationGO:0002696800.802
negative regulation of natural killer cell mediated immunityGO:000271650.801
regulation of leukocyte activationGO:00026941150.797
negative regulation of multicellular organismal processGO:00512413170.794
immune responseGO:00069553070.792
regulation of interferon gamma productionGO:0032649360.780
response to bacteriumGO:00096171440.780
leukocyte proliferationGO:0070661740.779
memory t cell activationGO:003570910.776
immune system developmentGO:00025201950.774
regulation of lymphocyte differentiationGO:0045619220.773
positive regulation of developmental processGO:00510943140.765
regulation of lymphocyte proliferationGO:0050670640.764
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.763
leukocyte mediated immunityGO:0002443590.760
regulation of adaptive immune responseGO:0002819330.744
regulation of leukocyte mediated cytotoxicityGO:0001910190.742
t cell activationGO:0042110990.737
leukocyte mediated cytotoxicityGO:0001909270.737
positive regulation of tolerance inductionGO:000264520.736
regulation of defense responseGO:00313471540.732
antigen processing and presentation of endogenous peptide antigenGO:000248360.732
response to other organismGO:00517072610.727
regulation of memory t cell activationGO:200056710.723
leukocyte differentiationGO:0002521980.723
negative regulation of immune system processGO:00026831360.714
regulation of innate immune responseGO:0045088970.708
lymphocyte mediated immunityGO:0002449480.707
regulation of cell differentiationGO:00455953930.706
positive regulation of cell activationGO:0050867810.705
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247620.685
positive regulation of lymphocyte mediated immunityGO:0002708230.685
negative regulation of developmental processGO:00510932470.682
positive regulation of t cell differentiationGO:0045582110.680
positive regulation of immune system processGO:00026842830.677
negative regulation of leukocyte proliferationGO:0070664160.677
positive regulation of leukocyte differentiationGO:1902107370.670
positive regulation of cell killingGO:0031343190.668
inorganic ion import into cellGO:009958720.666
positive regulation of t cell activationGO:0050870540.660
regulation of cell activationGO:00508651250.652
positive regulation of cell differentiationGO:00455972110.650
hemopoiesisGO:00300971800.633
positive regulation of lymphocyte activationGO:0051251730.616
immune effector processGO:00022521590.612
response to external biotic stimulusGO:00432072610.612
anatomical structure homeostasisGO:00602491000.609
negative regulation of immune effector processGO:0002698380.583
regulation of tolerance inductionGO:000264340.576
adaptive immune responseGO:0002250490.575
t cell proliferationGO:0042098450.573
neurological system processGO:00508771630.572
symbiosis encompassing mutualism through parasitismGO:00444031560.559
negative regulation of cell activationGO:0050866330.551
sensory perceptionGO:00076001030.537
positive regulation of leukocyte mediated immunityGO:0002705240.532
immune response regulating cell surface receptor signaling pathwayGO:0002768510.513
regulation of interleukin 12 productionGO:0032655150.490
cd8 positive alpha beta t cell activationGO:003603730.487
regulation of lymphocyte activationGO:00512491030.482
positive regulation of immune responseGO:00507781590.472
response to biotic stimulusGO:00096072760.468
leukocyte activationGO:00453211640.462
type i interferon signaling pathwayGO:0060337110.453
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.452
regulation of osteoblast differentiationGO:0045667380.442
lymphocyte activationGO:00466491330.441
negative regulation of immune responseGO:0050777400.440
regulation of immune effector processGO:0002697910.413
negative regulation of mononuclear cell proliferationGO:0032945150.401
lymphocyte differentiationGO:0030098350.394
iron ion transportGO:0006826120.389
cell activationGO:00017752130.379
system processGO:00030083490.378
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.362
t cell differentiationGO:0030217290.352
regulatory t cell differentiationGO:004506650.349
positive regulation of t cell mediated cytotoxicityGO:000191670.348
negative regulation of cell killingGO:003134250.321
biological adhesionGO:00226103310.299
regulation of t cell differentiationGO:0045580190.269
positive regulation of immune effector processGO:0002699400.248
negative regulation of lymphocyte activationGO:0051250240.240
regulation of immune responseGO:00507762010.220
regulation of lymphocyte mediated immunityGO:0002706330.201
t cell differentiation in thymusGO:003307740.171
response to interferon gammaGO:0034341390.148
negative regulation of lymphocyte proliferationGO:0050672150.131
ubiquitin dependent protein catabolic processGO:00065112060.129
detection of chemical stimulus involved in sensory perception of bitter tasteGO:0001580280.124
post embryonic developmentGO:000979120.121
ossificationGO:00015031210.120
negative regulation of cellular protein metabolic processGO:00322693530.117
regulation of secretionGO:00510461940.105
cell projection organizationGO:00300302520.103
proteolysis involved in cellular protein catabolic processGO:00516032440.092
cellular response to oxidative stressGO:0034599850.085
positive regulation of cellular amine metabolic processGO:003324070.078
negative regulation of phosphorylationGO:00423261740.075
cellular homeostasisGO:00197251960.064
regulation of cellular ketone metabolic processGO:0010565500.063
modification dependent macromolecule catabolic processGO:00436322120.062
negative regulation of intracellular signal transductionGO:19025321830.056
metal ion homeostasisGO:00550651690.055
modification dependent protein catabolic processGO:00199412090.054
multicellular organismal agingGO:001025930.051
response to metal ionGO:0010038840.051
cytoplasmic transportGO:00164823790.050
cellular amino acid metabolic processGO:00065201160.050
mapk cascadeGO:00001652880.043
regulation of growthGO:00400081650.042
response to thyroid hormoneGO:009706690.041
chemical homeostasisGO:00488783060.040
cation homeostasisGO:00550801890.040
intracellular protein transportGO:00068862700.039
regulation of viral genome replicationGO:0045069480.038
regulation of cellular amino acid metabolic processGO:000652160.035
cellular macromolecule catabolic processGO:00442653800.035
viral gene expressionGO:0019080350.034
secretion by cellGO:00329402260.032
cellular response to interferon gammaGO:0071346240.032
cellular protein catabolic processGO:00442572610.032
atp metabolic processGO:00460341760.031
purine ribonucleoside metabolic processGO:00461284370.030
regulation of cell migrationGO:00303342890.030
iron ion importGO:009728650.030
blastoderm segmentationGO:000735020.030
mitotic cell cycle processGO:19030472860.030
regulation of cellular component movementGO:00512703340.030
negative regulation of tyrosine phosphorylation of stat3 proteinGO:004251820.029
cellular amine metabolic processGO:0044106410.029
proteasomal protein catabolic processGO:00104981760.027
regulation of cellular response to stressGO:00801352440.026
ion homeostasisGO:00508012300.026
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.025
negative regulation of cell developmentGO:0010721480.025
regulation of locomotionGO:00400123290.025
determination of adult lifespanGO:000834020.024
response to inorganic substanceGO:00100351270.023
carbohydrate homeostasisGO:0033500310.023
embryo developmentGO:00097901230.023
oocyte differentiationGO:000999420.022
negative regulation of phosphorus metabolic processGO:00105632670.022
regulation of cell cycleGO:00517263930.022
purine containing compound catabolic processGO:00725234110.022
regulation of membrane potentialGO:0042391950.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
purine ribonucleotide catabolic processGO:00091544040.021
purine nucleoside monophosphate metabolic processGO:00091261860.020
growthGO:00400072020.018
atp catabolic processGO:00062001570.018
response to peptidoglycanGO:003249430.018
negative regulation of fibroblast proliferationGO:0048147120.018
segmentationGO:003528240.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.018
negative regulation of cell deathGO:00605483450.018
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.017
neuron projection developmentGO:00311751060.017
secretionGO:00469032540.017
cellular ion homeostasisGO:00068731680.017
single organism cellular localizationGO:19025803320.017
cytokine production involved in immune responseGO:0002367270.016
regulation of calcium ion transportGO:0051924790.016
mitotic spindle organizationGO:0007052270.016
protein localization to organelleGO:00333652800.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
regulation of proteolysisGO:00301622930.016
single organism membrane organizationGO:00448022680.015
negative regulation of protein metabolic processGO:00512483910.015
amine metabolic processGO:0009308440.015
vesicle mediated transportGO:00161923710.015
regulation of response to woundingGO:19030341010.015
response to type i interferonGO:0034340140.015
negative regulation of phosphate metabolic processGO:00459362670.015
cellular lipid metabolic processGO:00442553030.015
protein maturationGO:00516042330.015
oogenesisGO:004847720.015
ribonucleotide catabolic processGO:00092614050.015
neuron developmentGO:00486661130.014
negative regulation of protein modification processGO:00314002000.014
regulation of cell motilityGO:20001452990.014
mitochondrion organizationGO:00070051560.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
circulatory system developmentGO:00723592620.014
regulation of interleukin 10 secretionGO:200117940.014
microtubule cytoskeleton organizationGO:00002261760.014
single organismal cell cell adhesionGO:00163371480.014
signal transduction by phosphorylationGO:00230142970.014
receptor internalizationGO:0031623430.014
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.014
response to axon injuryGO:004867810.013
intracellular receptor signaling pathwayGO:00305221040.013
defense response to bacteriumGO:0042742630.013
myosin filament organizationGO:003103320.013
cellular protein complex assemblyGO:00436231880.013
lipid metabolic processGO:00066293810.013
microtubule based processGO:00070172100.013
cell developmentGO:00484683280.013
tube morphogenesisGO:0035239950.013
regulation of apoptotic signaling pathwayGO:20012331750.013
chromosome segregationGO:00070591140.012
protein oligomerizationGO:00512591730.012
nervous system developmentGO:00073992930.012
regulation of protein localizationGO:00328802960.012
regulation of mapk cascadeGO:00434082620.012
negative regulation of protein phosphorylationGO:00019331400.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
mitotic sister chromatid segregationGO:0000070530.012
single organism carbohydrate metabolic processGO:00447231930.012
fibroblast proliferationGO:0048144330.012
blood vessel maturationGO:000195510.012
response to oxygen containing compoundGO:19017003690.012
negative regulation of cellular amino acid metabolic processGO:004576320.012
regulation of chromosome organizationGO:00330441030.011
positive regulation of endocytosisGO:0045807420.011
generation of neuronsGO:00486991520.011
epithelium developmentGO:00604292270.011
response to peptideGO:1901652650.011
cellular ketone metabolic processGO:0042180800.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
detection of muramyl dipeptideGO:003249810.011
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.011
purine ribonucleotide biosynthetic processGO:0009152790.011
positive regulation of cytosolic calcium ion concentrationGO:0007204820.011
nucleoside catabolic processGO:00091644080.011
generation of precursor metabolites and energyGO:0006091680.011
sister chromatid segregationGO:0000819540.011
pattern recognition receptor signaling pathwayGO:0002221480.011
tripartite regional subdivisionGO:000735120.011
response to woundingGO:00096111680.011
protein ubiquitinationGO:00165673140.010
single organism reproductive processGO:0044702980.010
negative regulation of catalytic activityGO:00430863350.010
positive regulation of secretionGO:00510471160.010
regulation of purine nucleotide metabolic processGO:19005422640.010
entry into host cellGO:0030260250.010
i kappab kinase nf kappab signalingGO:00072491660.010
defense response to other organismGO:00985421290.010
cellular response to dna damage stimulusGO:00069743790.010
establishment or maintenance of apical basal cell polarityGO:003508820.010

HLA-B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease by infectious agentDOID:0050117340.763
human immunodeficiency virus infectious diseaseDOID:526130.763
viral infectious diseaseDOID:934130.763
acquired immunodeficiency syndromeDOID:635130.763
integumentary system diseaseDOID:16430.240
skin diseaseDOID:37330.061
immune system diseaseDOID:29141550.033
severe combined immunodeficiencyDOID:627100.019
primary immunodeficiency diseaseDOID:612360.019
combined t cell and b cell immunodeficiencyDOID:628120.019
disease of cellular proliferationDOID:145661740.018
musculoskeletal system diseaseDOID:172230.014
bone diseaseDOID:0080001880.009
connective tissue diseaseDOID:651090.009
bone inflammation diseaseDOID:3342100.001