Homo sapiens

113 known processes

HLA-A

major histocompatibility complex, class I, A

(Aliases: FLJ26655,HLAA)

HLA-A biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulus involved in sensory perceptionGO:0050907331.000
Human
antigen processing and presentation via mhc class ibGO:000247531.000
Human
immune response inhibiting cell surface receptor signaling pathwayGO:000276741.000
Human
positive regulation of natural killer cell mediated immunityGO:0002717121.000
Human
sensory perception of chemical stimulusGO:0007606381.000
Human
antigen processing and presentation of endogenous antigenGO:001988371.000
detection of external biotic stimulusGO:0098581191.000
regulation of dendritic cell differentiationGO:200119831.000
Human
regulation of natural killer cell mediated cytotoxicityGO:0042269161.000
sensory perception of tasteGO:0050909361.000
Human
antigen processing and presentation of peptide antigenGO:0048002181.000
detection of biotic stimulusGO:0009595211.000
detection of chemical stimulusGO:0009593551.000
Human
positive regulation of regulatory t cell differentiationGO:004559131.000
Human
negative regulation of leukocyte mediated cytotoxicityGO:000191151.000
negative regulation of dendritic cell differentiationGO:200119921.000
Human
negative regulation of leukocyte mediated immunityGO:0002704141.000
positive regulation of t cell tolerance inductionGO:000266621.000
Human
negative regulation of t cell proliferationGO:004213080.999
Human
antigen processing and presentation of peptide antigen via mhc class iGO:000247460.999
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988550.999
regulation of regulatory t cell differentiationGO:004558940.999
Human
negative regulation of natural killer cell mediated cytotoxicityGO:004595350.999
regulation of leukocyte mediated cytotoxicityGO:0001910190.998
detection of stimulusGO:0051606850.998
antigen processing and presentation of endogenous peptide antigen via mhc class ibGO:000247620.998
Human
tolerance inductionGO:000250760.998
Human
t cell tolerance inductionGO:000251740.997
Human
immune response inhibiting signal transductionGO:000276540.996
Human
dendritic cell differentiationGO:0097028130.996
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway tap independentGO:000248630.996
sensory perception of bitter tasteGO:0050913280.996
Human
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathwayGO:000248430.995
iron ion import into cellGO:009745920.995
Human
retina homeostasisGO:0001895420.995
Human
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.995
Human
antigen processing and presentation of peptide antigen via mhc class ibGO:000242820.993
Human
positive regulation of leukocyte mediated cytotoxicityGO:0001912160.993
detection of other organismGO:0098543130.991
negative regulation of lymphocyte mediated immunityGO:0002707120.988
regulation of t cell mediated immunityGO:0002709180.986
cell killingGO:0001906340.985
transition metal ion transportGO:0000041230.985
Human
tissue homeostasisGO:0001894630.984
Human
negative regulation of leukocyte differentiationGO:1902106240.982
Human
positive regulation of lymphocyte differentiationGO:0045621130.981
Human
regulation of leukocyte mediated immunityGO:0002703380.981
regulation of lymphocyte mediated immunityGO:0002706330.979
adaptive immune responseGO:0002250490.979
positive regulation of lymphocyte mediated immunityGO:0002708230.979
t cell mediated cytotoxicityGO:000191390.979
natural killer cell mediated cytotoxicityGO:0042267230.976
cation transportGO:00068123310.976
Human
positive regulation of leukocyte mediated immunityGO:0002705240.975
regulation of cell killingGO:0031341220.975
regulation of natural killer cell mediated immunityGO:0002715160.975
positive regulation of interleukin 12 productionGO:003273580.974
Human
import into cellGO:009865720.974
Human
natural killer cell mediated immunityGO:0002228230.973
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.968
response to other organismGO:00517072610.967
regulation of t cell mediated cytotoxicityGO:000191480.963
response to biotic stimulusGO:00096072760.953
inorganic cation import into cellGO:009865920.951
Human
lymphocyte mediated immunityGO:0002449480.950
multicellular organismal homeostasisGO:0048871670.937
Human
interferon gamma productionGO:0032609390.937
response to external biotic stimulusGO:00432072610.935
type i interferon signaling pathwayGO:0060337110.935
regulation of adaptive immune responseGO:0002819330.931
positive regulation of t cell mediated immunityGO:0002711120.929
positive regulation of cell killingGO:0031343190.927
regulation of t cell tolerance inductionGO:000266440.915
Human
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.913
negative regulation of natural killer cell mediated immunityGO:000271650.902
positive regulation of tolerance inductionGO:000264520.893
Human
antigen processing and presentationGO:0019882330.889
defense responseGO:00069523150.881
negative regulation of cell proliferationGO:00082852280.878
Human
negative regulation of leukocyte activationGO:0002695260.875
Human
positive regulation of adaptive immune responseGO:0002821210.875
detection of bacteriumGO:0016045130.868
regulation of innate immune responseGO:0045088970.865
regulation of t cell activationGO:0050863770.864
positive regulation of memory t cell activationGO:200056810.863
regulation of leukocyte proliferationGO:0070663670.861
Human
cell adhesionGO:00071553250.835
Human
positive regulation of cytokine productionGO:00018191670.829
anatomical structure homeostasisGO:00602491000.828
Human
immune response regulating cell surface receptor signaling pathwayGO:0002768510.824
Human
leukocyte mediated cytotoxicityGO:0001909270.824
negative regulation of immune responseGO:0050777400.821
innate immune responseGO:00450871780.809
negative regulation of defense responseGO:0031348470.806
regulation of tolerance inductionGO:000264340.804
Human
negative regulation of multicellular organismal processGO:00512413170.799
Human
t cell mediated immunityGO:0002456250.791
symbiosis encompassing mutualism through parasitismGO:00444031560.786
interleukin 12 productionGO:0032615150.780
Human
antigen processing and presentation of endogenous peptide antigenGO:000248360.777
immune effector processGO:00022521590.775
positive regulation of interferon gamma productionGO:0032729260.771
positive regulation of t cell mediated cytotoxicityGO:000191670.766
positive regulation of developmental processGO:00510943140.758
Human
t cell activationGO:0042110990.754
regulation of immune effector processGO:0002697910.749
regulation of defense responseGO:00313471540.745
negative regulation of innate immune responseGO:0045824180.736
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.716
system processGO:00030083490.712
Human
immune response regulating signaling pathwayGO:0002764970.711
Human
positive regulation of cell differentiationGO:00455972110.705
Human
positive regulation of leukocyte differentiationGO:1902107370.697
Human
lymphocyte proliferationGO:0046651700.693
Human
positive regulation of leukocyte activationGO:0002696800.678
positive regulation of innate immune responseGO:0045089790.670
Human
regulation of cell differentiationGO:00455953930.669
Human
immune responseGO:00069553070.662
hematopoietic or lymphoid organ developmentGO:00485341860.627
Human
response to bacteriumGO:00096171440.627
regulation of lymphocyte activationGO:00512491030.626
cd8 positive alpha beta t cell activationGO:003603730.618
leukocyte proliferationGO:0070661740.608
Human
neurological system processGO:00508771630.600
Human
regulation of cell activationGO:00508651250.595
mononuclear cell proliferationGO:0032943710.588
Human
biological adhesionGO:00226103310.575
Human
detection of stimulus involved in sensory perceptionGO:0050906430.574
Human
sensory perceptionGO:00076001030.558
Human
positive regulation of immune responseGO:00507781590.557
regulation of t cell differentiationGO:0045580190.552
Human
negative regulation of immune effector processGO:0002698380.532
regulation of interferon gamma productionGO:0032649360.524
positive regulation of defense responseGO:0031349870.521
Human
negative regulation of immune system processGO:00026831360.519
positive regulation of immune system processGO:00026842830.511
regulation of immune responseGO:00507762010.497
regulation of leukocyte differentiationGO:1902105610.495
Human
negative regulation of cell killingGO:003134250.488
negative regulation of developmental processGO:00510932470.487
Human
regulation of leukocyte activationGO:00026941150.484
negative regulation of cell differentiationGO:00455961710.473
Human
regulation of cytokine productionGO:00018172320.466
cell activationGO:00017752130.453
positive regulation of immune effector processGO:0002699400.448
negative regulation of leukocyte proliferationGO:0070664160.427
Human
inorganic ion import into cellGO:009958720.425
Human
negative regulation of lymphocyte proliferationGO:0050672150.417
Human
leukocyte differentiationGO:0002521980.410
Human
immune system developmentGO:00025201950.409
Human
regulation of t cell proliferationGO:0042129420.404
Human
lymphocyte differentiationGO:0030098350.395
Human
regulation of interleukin 12 productionGO:0032655150.385
Human
regulation of mononuclear cell proliferationGO:0032944650.374
Human
lymphocyte activationGO:00466491330.353
memory t cell activationGO:003570910.348
leukocyte mediated immunityGO:0002443590.339
hemopoiesisGO:00300971800.332
Human
positive regulation of t cell differentiationGO:0045582110.308
Human
metal ion transportGO:00300012720.299
Human
negative regulation of cell activationGO:0050866330.286
Human
cytokine productionGO:00018162470.276
leukocyte activationGO:00453211640.252
t cell differentiationGO:0030217290.239
Human
interleukin 6 productionGO:0032635370.220
post embryonic developmentGO:000979120.218
positive regulation of t cell activationGO:0050870540.212
regulation of memory t cell activationGO:200056710.209
positive regulation of cell activationGO:0050867810.204
cytoplasmic transportGO:00164823790.180
protection from natural killer cell mediated cytotoxicityGO:004227030.174
negative regulation of lymphocyte activationGO:0051250240.150
Human
t cell differentiation in thymusGO:003307740.149
viral gene expressionGO:0019080350.124
detection of chemical stimulus involved in sensory perception of bitter tasteGO:0001580280.115
Human
regulation of lymphocyte proliferationGO:0050670640.110
Human
response to interferon gammaGO:0034341390.102
iron ion transportGO:0006826120.099
Human
nucleotide catabolic processGO:00091664080.096
intracellular protein transportGO:00068862700.092
response to type i interferonGO:0034340140.091
regulatory t cell differentiationGO:004506650.090
Human
interaction with hostGO:0051701420.090
regulation of lymphocyte differentiationGO:0045619220.081
Human
chemical homeostasisGO:00488783060.078
cellular response to oxidative stressGO:0034599850.076
negative regulation of cellular protein metabolic processGO:00322693530.073
cation homeostasisGO:00550801890.072
purine containing compound catabolic processGO:00725234110.072
negative regulation of mononuclear cell proliferationGO:0032945150.070
Human
ribonucleoside monophosphate catabolic processGO:00091581580.070
nucleoside monophosphate metabolic processGO:00091231910.066
mapk cascadeGO:00001652880.064
response to muramyl dipeptideGO:003249540.063
ion homeostasisGO:00508012300.061
response to inorganic substanceGO:00100351270.056
purine ribonucleoside metabolic processGO:00461284370.051
ribonucleoside monophosphate metabolic processGO:00091611870.050
detection of muramyl dipeptideGO:003249810.047
purine ribonucleoside triphosphate metabolic processGO:00092054110.046
purine nucleoside catabolic processGO:00061523980.046
cell projection organizationGO:00300302520.046
nucleoside catabolic processGO:00091644080.045
negative regulation of t cell activationGO:0050868180.040
Human
regulation of cell migrationGO:00303342890.039
cytokine production involved in immune responseGO:0002367270.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
cellular amine metabolic processGO:0044106410.036
multicellular organismal agingGO:001025930.036
positive regulation of cellular amine metabolic processGO:003324070.035
t cell proliferationGO:0042098450.033
Human
protein refoldingGO:0042026140.032
purine ribonucleoside monophosphate metabolic processGO:00091671860.032
regulation of cellular ketone metabolic processGO:0010565500.031
interleukin 13 biosynthetic processGO:004223110.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
positive regulation of cysteine type endopeptidase activityGO:2001056790.030
entry into host cellGO:0030260250.029
purine ribonucleotide catabolic processGO:00091544040.028
cellular response to oxygen containing compoundGO:19017012760.028
response to drugGO:0042493810.027
peptide transportGO:0015833740.027
purine nucleotide catabolic processGO:00061954050.027
positive regulation of cell deathGO:00109422630.027
multi organism cellular processGO:00447641560.027
detection of peptidoglycanGO:003249910.027
ribonucleoside triphosphate catabolic processGO:00092033910.026
negative regulation of protein activation cascadeGO:200025870.025
purine nucleoside monophosphate metabolic processGO:00091261860.025
ossificationGO:00015031210.025
secretionGO:00469032540.025
regulation of cellular amino acid metabolic processGO:000652160.025
ribonucleotide catabolic processGO:00092614050.025
nucleoside triphosphate catabolic processGO:00091433940.025
metal ion homeostasisGO:00550651690.025
response to molecule of bacterial originGO:0002237820.024
cellular response to interferon gammaGO:0071346240.024
nucleoside phosphate catabolic processGO:19012924120.024
regulation of secretion by cellGO:19035301770.024
protein maturationGO:00516042330.023
atp metabolic processGO:00460341760.023
protein foldingGO:0006457380.023
response to oxygen containing compoundGO:19017003690.022
cellular response to type i interferonGO:0071357120.022
dna catabolic process exonucleolyticGO:0000738170.022
purine nucleoside triphosphate metabolic processGO:00091444120.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
regulation of purine nucleotide metabolic processGO:19005422640.021
regulation of kinase activityGO:00435493140.021
transmission of nerve impulseGO:0019226110.021
amide transportGO:0042886760.020
negative regulation of cell deathGO:00605483450.020
carbohydrate homeostasisGO:0033500310.020
nucleoside monophosphate catabolic processGO:00091251590.020
cellular response to lipidGO:00713961270.020
organophosphate catabolic processGO:00464344300.020
protein localization to organelleGO:00333652800.019
regulation of ossificationGO:0030278580.019
atp catabolic processGO:00062001570.019
nucleoside triphosphate metabolic processGO:00091414220.019
purine nucleoside monophosphate catabolic processGO:00091281580.019
lipid metabolic processGO:00066293810.019
regulation of cell cycleGO:00517263930.018
regulation of cellular amine metabolic processGO:0033238110.018
maintenance of location in cellGO:0051651620.018
collagen catabolic processGO:0030574100.018
negative regulation of protein metabolic processGO:00512483910.018
mitotic spindle organizationGO:0007052270.017
regulation of nucleotide metabolic processGO:00061402690.017
cellular response to nutrient levelsGO:0031669690.017
regulation of branching involved in ureteric bud morphogenesisGO:009018930.017
determination of adult lifespanGO:000834020.017
regulation of protein localizationGO:00328802960.016
negative regulation of multi organism processGO:0043901920.016
sensory perception of sweet tasteGO:005091620.016
blastoderm segmentationGO:000735020.016
regulation of ion homeostasisGO:2000021730.015
negative regulation of protein modification processGO:00314002000.015
response to nitrogen compoundGO:19016981840.015
maintenance of locationGO:00512351120.015
negative regulation of intracellular signal transductionGO:19025321830.015
secretion by cellGO:00329402260.015
negative regulation of type i interferon mediated signaling pathwayGO:006033940.014
regulation of ion transportGO:00432691890.014
positive regulation of nucleoside metabolic processGO:00459791860.014
response to virusGO:00096151260.014
amine metabolic processGO:0009308440.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.014
negative regulation of hydrolase activityGO:00513461820.013
negative regulation of cytoplasmic transportGO:1903650460.013
positive regulation of cellular catabolic processGO:00313312840.013
regulation of complement activation lectin pathwayGO:000186820.013
regulation of hormone levelsGO:00108171250.013
regulation of cytoplasmic transportGO:19036491490.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
regulation of cellular component movementGO:00512703340.013
muscle structure developmentGO:0061061980.012
multi organism metabolic processGO:0044033410.012
antigen processing and presentation of exogenous peptide antigenGO:000247840.012
viral transcriptionGO:0019083350.012
regulation of calcium ion transportGO:0051924790.012
negative regulation of catalytic activityGO:00430863350.012
osteoblast differentiationGO:0001649920.012
regulation of secretionGO:00510461940.012
positive regulation of secretionGO:00510471160.012
cellular ketone metabolic processGO:0042180800.012
response to thyroid hormoneGO:009706690.012
negative regulation of viral processGO:0048525660.011
positive regulation of programmed cell deathGO:00430682490.011
negative regulation of phosphorus metabolic processGO:00105632670.011
defense response to other organismGO:00985421290.011
regulation of cellular response to stressGO:00801352440.011
regulation of cell motilityGO:20001452990.011
single organism membrane organizationGO:00448022680.011
cellular response to cytokine stimulusGO:00713451810.011
negative regulation of protein transportGO:0051224750.011
positive regulation of hydrolase activityGO:00513453310.011
cellular amino acid metabolic processGO:00065201160.011
actin filament based movementGO:0030048170.011
carbohydrate derivative biosynthetic processGO:19011372070.011
oocyte developmentGO:004859910.011
entry into hostGO:0044409250.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of viral genome replicationGO:0045069480.011
negative regulation of cellular amine metabolic processGO:003323930.011
regulation of cell developmentGO:00602841610.010
apoptotic signaling pathwayGO:00971902680.010
anterior posterior axis specification embryoGO:000859520.010
single organism carbohydrate metabolic processGO:00447231930.010
regulation of purine nucleotide catabolic processGO:00331212050.010
nitrogen compound transportGO:00717051910.010
regulation of elastin catabolic processGO:006031010.010
regulation of osteoblast differentiationGO:0045667380.010
transition metal ion homeostasisGO:0055076310.010
positive regulation of cellular amino acid metabolic processGO:004576430.010
regulation of cell projection organizationGO:00313441070.010

HLA-A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
acquired immunodeficiency syndromeDOID:635130.869
Human
disease by infectious agentDOID:0050117340.869
Human
human immunodeficiency virus infectious diseaseDOID:526130.869
Human
viral infectious diseaseDOID:934130.869
Human
musculoskeletal system diseaseDOID:172230.809
immune system diseaseDOID:29141550.184
combined t cell and b cell immunodeficiencyDOID:628120.184
severe combined immunodeficiencyDOID:627100.184
primary immunodeficiency diseaseDOID:612360.184
connective tissue diseaseDOID:651090.107
bone diseaseDOID:0080001880.107
disease of metabolismDOID:00146672950.033
Human
organ system cancerDOID:00506861640.025
disease of cellular proliferationDOID:145661740.025
cancerDOID:1621670.025
inherited metabolic disorderDOID:6552420.020
Human
integumentary system diseaseDOID:16430.015
Human
vascular diseaseDOID:178250.012
cardiovascular system diseaseDOID:12871060.012
nervous system diseaseDOID:8634310.011
Human
sensory system diseaseDOID:00501552030.011
brain diseaseDOID:936730.010
leukodystrophyDOID:1057980.010
cerebral degenerationDOID:1443160.010
central nervous system diseaseDOID:3311860.010
Human