Homo sapiens

18 known processes

SPPL2A

signal peptide peptidase-like 2A

(Aliases: IMP3,PSL2)

SPPL2A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123310.114
post embryonic developmentGO:000979120.112
secretionGO:00469032540.093
metal ion homeostasisGO:00550651690.090
ribonucleoside triphosphate metabolic processGO:00091994120.070
lipid metabolic processGO:00066293810.067
metal ion transportGO:00300012720.062
cellular homeostasisGO:00197251960.061
cellular metal ion homeostasisGO:00068751460.060
cation homeostasisGO:00550801890.057
cellular cation homeostasisGO:00300031630.055
regulation of response to external stimulusGO:00321012220.054
proteolysis involved in cellular protein catabolic processGO:00516032440.050
intracellular protein transportGO:00068862700.047
ion homeostasisGO:00508012300.045
cellular macromolecule catabolic processGO:00442653800.045
response to oxygen containing compoundGO:19017003690.045
cellular ion homeostasisGO:00068731680.044
purine ribonucleoside metabolic processGO:00461284370.044
cellular chemical homeostasisGO:00550821800.043
organophosphate catabolic processGO:00464344300.043
innate immune responseGO:00450871780.040
female gamete generationGO:000729220.039
purine containing compound catabolic processGO:00725234110.037
negative regulation of cell deathGO:00605483450.036
regulation of cellular amino acid metabolic processGO:000652160.036
negative regulation of programmed cell deathGO:00430693210.035
defense responseGO:00069523150.035
divalent inorganic cation transportGO:00725111580.035
ribonucleotide catabolic processGO:00092614050.034
exocytosisGO:0006887710.034
regulation of i kappab kinase nf kappab signalingGO:00431221620.034
purine nucleoside triphosphate catabolic processGO:00091463920.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
determination of adult lifespanGO:000834020.033
cellular protein catabolic processGO:00442572610.033
nucleoside catabolic processGO:00091644080.033
positive regulation of cellular component organizationGO:00511303760.033
immune responseGO:00069553070.033
purine ribonucleotide catabolic processGO:00091544040.032
cytoplasmic transportGO:00164823790.032
response to biotic stimulusGO:00096072760.032
chemical homeostasisGO:00488783060.031
regulation of immune responseGO:00507762010.031
regulation of protein localizationGO:00328802960.030
cellular lipid metabolic processGO:00442553030.030
divalent inorganic cation homeostasisGO:00725071360.029
purine nucleoside catabolic processGO:00061523980.029
secretion by cellGO:00329402260.029
organic anion transportGO:00157111030.029
positive regulation of transportGO:00510503360.029
multicellular organismal agingGO:001025930.029
ribonucleoside triphosphate catabolic processGO:00092033910.028
cell adhesionGO:00071553250.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
anion transportGO:00068201610.028
signal transduction by phosphorylationGO:00230142970.028
apoptotic signaling pathwayGO:00971902680.027
single organism cellular localizationGO:19025803320.027
cellular component morphogenesisGO:00329893140.026
oogenesisGO:004847720.026
ribonucleoside catabolic processGO:00424544060.026
negative regulation of phosphorus metabolic processGO:00105632670.025
reactive oxygen species metabolic processGO:0072593750.024
biological adhesionGO:00226103310.024
transition metal ion transportGO:0000041230.024
establishment of protein localization to organelleGO:00725941720.024
organophosphate biosynthetic processGO:00904071630.023
neurological system processGO:00508771630.023
carbohydrate derivative biosynthetic processGO:19011372070.023
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.023
negative regulation of intracellular signal transductionGO:19025321830.023
nucleoside triphosphate metabolic processGO:00091414220.023
positive regulation of cellular amino acid metabolic processGO:004576430.023
lipid biosynthetic processGO:00086101770.023
regulation of ion transportGO:00432691890.023
nucleoside phosphate catabolic processGO:19012924120.023
carbohydrate metabolic processGO:00059752070.023
cellular response to endogenous stimulusGO:00714953360.023
guanosine containing compound metabolic processGO:19010682440.022
canonical wnt signaling pathwayGO:00600701160.022
regulation of secretionGO:00510461940.022
positive regulation of cell proliferationGO:00082843010.022
modification dependent macromolecule catabolic processGO:00436322120.022
cellular response to oxygen containing compoundGO:19017012760.022
reactive nitrogen species metabolic processGO:200105730.021
compound eye developmentGO:004874910.021
regulation of defense responseGO:00313471540.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
regulation of cellular ketone metabolic processGO:0010565500.021
positive regulation of cellular catabolic processGO:00313312840.021
i kappab kinase nf kappab signalingGO:00072491660.021
cellular amino acid metabolic processGO:00065201160.021
locomotory behaviorGO:000762610.021
positive regulation of developmental processGO:00510943140.021
regulation of purine nucleotide metabolic processGO:19005422640.020
negative regulation of apoptotic processGO:00430663160.020
immune system developmentGO:00025201950.020
response to cytokineGO:00340972320.020
inflammatory responseGO:0006954790.020
ras protein signal transductionGO:0007265730.020
cell morphogenesisGO:00009022960.019
negative regulation of apoptotic signaling pathwayGO:2001234970.019
peripheral nervous system developmentGO:000742220.019
positive regulation of cell migrationGO:00303351720.019
amine metabolic processGO:0009308440.019
calcium ion homeostasisGO:00550741220.019
immune effector processGO:00022521590.019
negative regulation of developmental processGO:00510932470.019
organonitrogen compound biosynthetic processGO:19015662000.019
cellular amine metabolic processGO:0044106410.019
oxidation reduction processGO:00551143960.019
segmentationGO:003528240.018
regulation of cytokine productionGO:00018172320.018
embryonic hemopoiesisGO:003516240.018
nucleotide catabolic processGO:00091664080.018
maintenance of locationGO:00512351120.018
negative regulation of catalytic activityGO:00430863350.018
glycoprotein biosynthetic processGO:0009101910.018
nucleoside triphosphate catabolic processGO:00091433940.018
positive regulation of immune system processGO:00026842830.018
oocyte differentiationGO:000999420.018
mapk cascadeGO:00001652880.018
divalent metal ion transportGO:00708381520.018
cellular response to nitrogen compoundGO:19016991440.018
negative regulation of response to external stimulusGO:0032102830.018
reactive oxygen species biosynthetic processGO:190340940.018
positive regulation of hydrolase activityGO:00513453310.018
anatomical structure homeostasisGO:00602491000.018
negative regulation of hydrolase activityGO:00513461820.018
stem cell divisionGO:001714520.018
system processGO:00030083490.018
regulation of innate immune responseGO:0045088970.018
positive regulation of cellular amine metabolic processGO:003324070.018
negative regulation of protein metabolic processGO:00512483910.017
actin filament based processGO:00300292240.017
cell projection organizationGO:00300302520.017
response to tumor necrosis factorGO:0034612760.017
protein localization to organelleGO:00333652800.017
blood vessel morphogenesisGO:00485141620.017
regulation of cell differentiationGO:00455953930.017
response to other organismGO:00517072610.017
guanosine containing compound catabolic processGO:19010692390.017
gtp catabolic processGO:00061842370.017
cell type specific apoptotic processGO:00972851250.017
myeloid leukocyte differentiationGO:0002573600.017
anatomical structure formation involved in morphogenesisGO:00486462840.017
vesicle mediated transportGO:00161923710.017
regulation of glial cell differentiationGO:004568530.017
small gtpase mediated signal transductionGO:0007264780.016
cellular response to external stimulusGO:00714961110.016
response to nitrogen compoundGO:19016981840.016
regulation of immune effector processGO:0002697910.016
single organism membrane organizationGO:00448022680.016
regulation of cell motilityGO:20001452990.016
positive regulation of nucleoside metabolic processGO:00459791860.016
response to organic cyclic compoundGO:00140702040.016
membrane organizationGO:00610242920.016
regulation of cell developmentGO:00602841610.016
regulation of nucleotide metabolic processGO:00061402690.016
syncytium formation by plasma membrane fusionGO:000076820.016
photoreceptor cell differentiationGO:004653020.016
negative regulation of cellular protein metabolic processGO:00322693530.016
negative regulation of phosphate metabolic processGO:00459362670.015
regulation of cell cycleGO:00517263930.015
blastoderm segmentationGO:000735020.015
purine ribonucleoside catabolic processGO:00461303980.015
protein maturationGO:00516042330.015
cellular response to starvationGO:0009267580.015
response to bacteriumGO:00096171440.015
posttranscriptional regulation of gene expressionGO:00106082130.015
glycosyl compound catabolic processGO:19016584130.015
cell developmentGO:00484683280.015
regulation of cell migrationGO:00303342890.015
positive regulation of purine nucleotide metabolic processGO:19005442270.015
regulation of nucleotide catabolic processGO:00308112050.015
myeloid cell differentiationGO:00300991170.015
cell projection morphogenesisGO:00488581290.015
glycoprotein metabolic processGO:00091001100.015
wnt signaling pathwayGO:00160551560.015
positive regulation of catabolic processGO:00098963100.015
memoryGO:000761330.014
mitochondrion organizationGO:00070051560.014
negative regulation of cell proliferationGO:00082852280.014
response to external biotic stimulusGO:00432072610.014
cellular macromolecular complex assemblyGO:00346223240.014
regulation of apoptotic signaling pathwayGO:20012331750.014
modification dependent protein catabolic processGO:00199412090.014
organic hydroxy compound metabolic processGO:19016151470.014
regulation of nucleoside metabolic processGO:00091182090.014
regulation of mapk cascadeGO:00434082620.014
regulation of cellular amine metabolic processGO:0033238110.014
positive regulation of phosphorylationGO:00423273940.014
glycerolipid metabolic processGO:00464861070.014
inorganic cation transmembrane transportGO:00986621940.014
purine nucleotide catabolic processGO:00061954050.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
positive regulation of innate immune responseGO:0045089790.014
regulation of gtpase activityGO:00430871800.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
ubiquitin dependent protein catabolic processGO:00065112060.014
single organism carbohydrate metabolic processGO:00447231930.014
cellular protein complex assemblyGO:00436231880.014
organic hydroxy compound biosynthetic processGO:1901617710.014
regulation of response to woundingGO:19030341010.014
regulation of cellular component biogenesisGO:00440872810.014
monocarboxylic acid metabolic processGO:00327871850.013
response to extracellular stimulusGO:0009991850.013
cellular ketone metabolic processGO:0042180800.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
myoblast fusionGO:000752010.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
regulation of anatomical structure morphogenesisGO:00226032860.013
regulation of multi organism processGO:00439001570.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
regulation of intracellular transportGO:00323861950.013
microtubule based processGO:00070172100.013
regulation of cellular response to stressGO:00801352440.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of cytoplasmic transportGO:19036491490.013
cation transmembrane transportGO:00986552380.013
response to abiotic stimulusGO:00096283360.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
regulation of proteolysisGO:00301622930.013
regulation of homeostatic processGO:00328441210.013
embryo developmentGO:00097901230.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
sulfur compound metabolic processGO:00067901010.013
long term memoryGO:000761620.013
regulation of establishment of protein localizationGO:00702012420.013
protein catabolic processGO:00301633250.013
endosomal transportGO:00161971290.013
organelle assemblyGO:00709251760.013
regulation of kinase activityGO:00435493140.013
establishment of protein localization to membraneGO:00901501210.013
ion transmembrane transportGO:00342203380.013
positive regulation of nucleotide catabolic processGO:00308131850.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
cell growthGO:00160491600.012
hemopoiesisGO:00300971800.012
regulation of wnt signaling pathwayGO:00301111230.012
protein processingGO:00164852260.012
erk1 and erk2 cascadeGO:00703711040.012
positive regulation of nucleotide metabolic processGO:00459812300.012
positive regulation of intracellular transportGO:00323881040.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
response to fungusGO:000962040.012
protein localization to nucleusGO:00345041360.012
hindbrain developmentGO:003090230.012
negative regulation of proteolysisGO:00458611320.012
gastrulation with mouth forming secondGO:000170210.012
sequestering of metal ionGO:0051238240.012
regulation of protein processingGO:00706131500.012
transition metal ion homeostasisGO:0055076310.012
single organism cell adhesionGO:00986021790.012
positive regulation of ras gtpase activityGO:00323201170.012
cellular response to cytokine stimulusGO:00713451810.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
response to drugGO:0042493810.012
protein importGO:00170381300.012
positive regulation of gtpase activityGO:00435471660.012
vacuolar transportGO:0007034340.012
cellular response to oxidative stressGO:0034599850.011
atp metabolic processGO:00460341760.011
gtp metabolic processGO:00460392390.011
cellular response to extracellular stimulusGO:0031668720.011
astrocyte differentiationGO:004870840.011
nuclear transportGO:00511691790.011
regulation of cell growthGO:00015581350.011
response to lipidGO:00339932060.011
cellular response to dna damage stimulusGO:00069743790.011
positive regulation of cell differentiationGO:00455972110.011
negative regulation of cell migrationGO:00303361020.011
purine ribonucleotide biosynthetic processGO:0009152790.011
epithelial tube branching involved in lung morphogenesisGO:006044140.011
endomembrane system organizationGO:00102561960.011
phosphatidic acid biosynthetic processGO:000665440.011
inorganic ion transmembrane transportGO:00986602310.011
organ formationGO:004864530.011
regulation of growthGO:00400081650.011
rna interferenceGO:001624640.011
cellular response to hormone stimulusGO:00328701250.011
regulation of gtp catabolic processGO:00331241800.011
cellular response to organonitrogen compoundGO:00714171240.011
phospholipid metabolic processGO:0006644990.011
cell cycle phase transitionGO:00447701730.011
cellular calcium ion homeostasisGO:00068741170.011
regulation of purine nucleotide catabolic processGO:00331212050.011
positive regulation of protein phosphorylationGO:00019343130.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
lysosomal transportGO:0007041330.011
generation of neuronsGO:00486991520.011
membrane lipid metabolic processGO:0006643530.011
mitotic cell cycleGO:00002783260.011
positive regulation of synaptic transmissionGO:005080640.011
regulation of transferase activityGO:00513383550.011
neuroblast proliferationGO:000740540.011
synaptic transmissionGO:0007268610.011
behaviorGO:00076101120.011
somitogenesisGO:000175620.011
response to inorganic substanceGO:00100351270.011
vasculature developmentGO:00019441810.011
negative regulation of transportGO:00510511760.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
golgi vesicle transportGO:0048193800.011
carboxylic acid transportGO:0046942630.011
circulatory system developmentGO:00723592620.011
positive regulation of immune responseGO:00507781590.011
pharynx developmentGO:006046510.011
hair follicle morphogenesisGO:003106920.010
monovalent inorganic cation transportGO:00156721280.010
nucleocytoplasmic transportGO:00069131760.010
regulation of dna metabolic processGO:00510521530.010
meiosis iGO:000712740.010
positive regulation of programmed cell deathGO:00430682490.010
embryonic forelimb morphogenesisGO:003511540.010
growthGO:00400072020.010
response to woundingGO:00096111680.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
regulation of protein transportGO:00512232130.010
cell activationGO:00017752130.010
protein localization to membraneGO:00726571600.010
myosin filament organizationGO:003103320.010
mitotic cell cycle phase transitionGO:00447721620.010
positive regulation of kinase activityGO:00336742040.010
positive regulation of apoptotic processGO:00430652460.010
cd4 positive alpha beta t cell differentiation involved in immune responseGO:000229440.010
negative regulation of protein modification processGO:00314002000.010
regulation of synaptic plasticityGO:004816730.010
response to hormoneGO:00097251750.010
positive regulation of transferase activityGO:00513472270.010
cell cell signalingGO:00072671550.010
positive regulation of locomotionGO:00400171860.010
blood vessel developmentGO:00015681720.010
regulation of cell morphogenesisGO:00226041530.010
epithelium developmentGO:00604292270.010

SPPL2A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.046
inherited metabolic disorderDOID:6552420.034
organ system cancerDOID:00506861640.026
cancerDOID:1621670.026
disease of cellular proliferationDOID:145661740.026
connective tissue diseaseDOID:651090.020
musculoskeletal system diseaseDOID:172230.020
sensory system diseaseDOID:00501552030.017
nervous system diseaseDOID:8634310.017
bone diseaseDOID:0080001880.012
brain diseaseDOID:936730.010
central nervous system diseaseDOID:3311860.010