Homo sapiens

0 known processes

USP18

ubiquitin specific peptidase 18

(Aliases: ISG43,UBP43)

USP18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
viral life cycleGO:00190581320.476
nucleoside phosphate biosynthetic processGO:19012931090.398
negative regulation of multi organism processGO:0043901920.225
protein modification by small protein conjugationGO:00324463420.186
chemical homeostasisGO:00488783060.179
response to other organismGO:00517072610.178
response to cytokineGO:00340972320.175
response to biotic stimulusGO:00096072760.167
cellular response to cytokine stimulusGO:00713451810.153
multi organism cellular processGO:00447641560.133
regulation of defense response to virusGO:0050688330.131
regulation of viral genome replicationGO:0045069480.122
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.117
regulation of multi organism processGO:00439001570.117
defense response to other organismGO:00985421290.114
positive regulation of myeloid cell differentiationGO:0045639390.111
protein catabolic processGO:00301633250.109
regulation of intracellular transportGO:00323861950.107
cytokine productionGO:00018162470.094
negative regulation of protein metabolic processGO:00512483910.088
cytoplasmic transportGO:00164823790.085
carbohydrate derivative biosynthetic processGO:19011372070.083
nuclear transportGO:00511691790.081
response to external biotic stimulusGO:00432072610.081
single organism cellular localizationGO:19025803320.080
viral genome replicationGO:0019079500.080
cellular macromolecule catabolic processGO:00442653800.079
defense responseGO:00069523150.076
defense response to virusGO:0051607710.075
positive regulation of cell deathGO:00109422630.075
negative regulation of viral processGO:0048525660.074
lipoprotein metabolic processGO:0042157420.071
interspecies interaction between organismsGO:00444191560.071
immune effector processGO:00022521590.070
organophosphate biosynthetic processGO:00904071630.070
immune responseGO:00069553070.067
rna interferenceGO:001624640.065
glycoprotein biosynthetic processGO:0009101910.065
negative regulation of catalytic activityGO:00430863350.063
response to interferon alphaGO:0035455110.061
purine nucleotide biosynthetic processGO:0006164840.061
proteolysis involved in cellular protein catabolic processGO:00516032440.060
carbohydrate metabolic processGO:00059752070.057
response to virusGO:00096151260.056
negative regulation of cellular protein metabolic processGO:00322693530.055
regulation of homeostatic processGO:00328441210.054
organonitrogen compound biosynthetic processGO:19015662000.053
protein ubiquitinationGO:00165673140.052
regulation of defense response to virus by hostGO:0050691220.051
symbiosis encompassing mutualism through parasitismGO:00444031560.050
regulation of cytokine productionGO:00018172320.049
cellular macromolecular complex assemblyGO:00346223240.048
protein localization to organelleGO:00333652800.048
nucleotide biosynthetic processGO:00091651090.048
negative regulation of programmed cell deathGO:00430693210.048
negative regulation of protein modification processGO:00314002000.046
glycosylationGO:0070085710.045
positive regulation of interferon alpha productionGO:0032727110.045
ion homeostasisGO:00508012300.045
interferon beta productionGO:0032608230.045
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.044
modification dependent protein catabolic processGO:00199412090.043
regulation of myeloid cell differentiationGO:0045637810.043
negative regulation of cell deathGO:00605483450.042
positive regulation of erythrocyte differentiationGO:0045648110.042
cellular response to organic cyclic compoundGO:00714071270.040
innate immune responseGO:00450871780.040
lipoprotein biosynthetic processGO:0042158330.039
glucose metabolic processGO:0006006450.039
protein acylationGO:00435431380.037
positive regulation of homeostatic processGO:0032846470.037
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.036
cellular protein catabolic processGO:00442572610.035
positive regulation of cell differentiationGO:00455972110.034
regulation of cellular component movementGO:00512703340.034
purine containing compound biosynthetic processGO:0072522880.033
modification dependent macromolecule catabolic processGO:00436322120.033
regulation of viral processGO:00507921030.032
regulation of anatomical structure morphogenesisGO:00226032860.032
positive regulation of hydrolase activityGO:00513453310.032
viral processGO:00160321460.032
positive regulation of programmed cell deathGO:00430682490.031
negative regulation of apoptotic signaling pathwayGO:2001234970.031
positive regulation of rig i signaling pathwayGO:190024640.031
positive regulation of immune system processGO:00026842830.030
response to type i interferonGO:0034340140.030
regulation of nucleocytoplasmic transportGO:0046822980.030
positive regulation of proteolysisGO:00458621420.030
regulation of cell motilityGO:20001452990.029
single organism membrane organizationGO:00448022680.028
negative regulation of viral genome replicationGO:0045071350.028
regulation of protein modification by small protein conjugation or removalGO:19033201070.027
glycoprotein metabolic processGO:00091001100.027
regulation of protein ubiquitinationGO:0031396950.027
myeloid cell differentiationGO:00300991170.027
posttranscriptional regulation of gene expressionGO:00106082130.027
negative regulation of apoptotic processGO:00430663160.026
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.026
positive regulation of intracellular protein transportGO:0090316760.026
negative regulation of response to external stimulusGO:0032102830.025
immune system developmentGO:00025201950.025
regulation of defense responseGO:00313471540.025
response to lipidGO:00339932060.025
macromolecule glycosylationGO:0043413630.025
negative regulation of protein ubiquitinationGO:0031397350.024
erythrocyte homeostasisGO:0034101310.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
hemopoiesisGO:00300971800.024
cellular response to interferon alphaGO:003545740.024
homeostasis of number of cellsGO:0048872400.023
regulation of apoptotic signaling pathwayGO:20012331750.023
nucleoside triphosphate metabolic processGO:00091414220.023
negative regulation of intracellular signal transductionGO:19025321830.023
chromatin organizationGO:00063253510.023
protein myristoylationGO:001837710.023
female gamete generationGO:000729220.023
nucleoside catabolic processGO:00091644080.023
nucleic acid phosphodiester bond hydrolysisGO:00903051020.023
protein importGO:00170381300.022
regulation of cytoplasmic transportGO:19036491490.022
nitrogen compound transportGO:00717051910.022
multicellular organismal agingGO:001025930.022
regulation of peptidase activityGO:00525471800.022
cellular response to endogenous stimulusGO:00714953360.022
mitochondrion organizationGO:00070051560.022
protein localization to nucleusGO:00345041360.022
nuclear importGO:00511701060.021
locomotory behaviorGO:000762610.021
regulation of protein catabolic processGO:00421761550.021
positive regulation of cellular catabolic processGO:00313312840.021
regulation of response to biotic stimulusGO:0002831550.021
nucleocytoplasmic transportGO:00069131760.021
negative regulation of hydrolase activityGO:00513461820.021
regulation of membrane potentialGO:0042391950.021
ribonucleoside catabolic processGO:00424544060.021
cellular amino acid metabolic processGO:00065201160.021
single organism nuclear importGO:19025931040.021
nucleoside triphosphate catabolic processGO:00091433940.021
positive regulation of cytoplasmic transportGO:1903651820.021
regulation of nuclease activityGO:0032069110.021
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.021
cellular response to dsrnaGO:0071359190.021
organic hydroxy compound metabolic processGO:19016151470.020
regulation of transferase activityGO:00513383550.020
negative regulation of cysteine type endopeptidase activityGO:2000117480.020
cellular response to oxygen containing compoundGO:19017012760.020
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.020
regulation of protein transportGO:00512232130.019
purine nucleoside catabolic processGO:00061523980.019
positive regulation of apoptotic processGO:00430652460.019
positive regulation of catabolic processGO:00098963100.019
organophosphate catabolic processGO:00464344300.019
hexose metabolic processGO:0019318550.019
response to abiotic stimulusGO:00096283360.019
regulation of cell differentiationGO:00455953930.019
protein targetingGO:00066051870.019
determination of adult lifespanGO:000834020.019
myeloid cell homeostasisGO:0002262340.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
positive regulation of type i interferon productionGO:0032481200.019
post embryonic developmentGO:000979120.019
rna processingGO:00063962550.018
nucleotide catabolic processGO:00091664080.018
mitotic cell cycle processGO:19030472860.018
purine ribonucleoside catabolic processGO:00461303980.018
single organism carbohydrate metabolic processGO:00447231930.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
ribonucleoprotein complex subunit organizationGO:0071826810.018
atp metabolic processGO:00460341760.018
regulation of ion homeostasisGO:2000021730.018
protein processingGO:00164852260.018
glycosyl compound catabolic processGO:19016584130.017
protein lipidationGO:0006497330.017
purine ribonucleotide catabolic processGO:00091544040.017
protein glycosylationGO:0006486620.017
posttranscriptional gene silencingGO:0016441250.017
response to nitrogen compoundGO:19016981840.017
positive regulation of transferase activityGO:00513472270.017
purine nucleoside triphosphate metabolic processGO:00091444120.016
behavioral response to ethanolGO:004814920.016
nucleoside phosphate catabolic processGO:19012924120.016
positive regulation of intracellular transportGO:00323881040.016
protein oligomerizationGO:00512591730.016
negative regulation of mitochondrial depolarizationGO:005190220.016
cellular response to glucocorticoid stimulusGO:007138540.016
actin filament based processGO:00300292240.016
negative regulation of phosphate metabolic processGO:00459362670.016
regulation of cellular response to stressGO:00801352440.016
regulation of intracellular protein transportGO:00331571230.015
regulation of erythrocyte differentiationGO:0045646170.015
dsrna fragmentationGO:0031050130.015
establishment of protein localization to organelleGO:00725941720.015
negative regulation of peptidase activityGO:0010466910.015
erythrocyte differentiationGO:0030218280.015
regulation of endopeptidase activityGO:00525481700.015
positive regulation of endopeptidase activityGO:0010950840.015
dephosphorylationGO:00163112090.015
positive regulation of multi organism processGO:0043902560.015
regulation of protein maturationGO:19033171500.015
membrane organizationGO:00610242920.015
regulation of cellular ketone metabolic processGO:0010565500.014
regulation of purine nucleotide metabolic processGO:19005422640.014
small gtpase mediated signal transductionGO:0007264780.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
negative regulation of kinase activityGO:00336731060.014
regulation of interferon beta productionGO:0032648220.014
regulation of response to external stimulusGO:00321012220.014
cellular protein complex assemblyGO:00436231880.014
protein import into nucleusGO:00066061040.014
negative regulation of defense response to virus by hostGO:005068940.014
glucose homeostasisGO:0042593310.014
purine containing compound catabolic processGO:00725234110.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
regulation of cellular amino acid metabolic processGO:000652160.014
positive regulation of cellular amino acid metabolic processGO:004576430.014
ras protein signal transductionGO:0007265730.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
negative regulation of cellular component organizationGO:00511292350.014
positive regulation of synaptic transmissionGO:005080640.013
protein targeting to nucleusGO:00447441040.013
signal transduction by phosphorylationGO:00230142970.013
release of cytochrome c from mitochondriaGO:0001836350.013
stress activated mapk cascadeGO:0051403930.013
small molecule biosynthetic processGO:00442831570.013
epinephrine transportGO:004824110.013
response to organic cyclic compoundGO:00140702040.013
mitotic cell cycleGO:00002783260.013
response to growth factorGO:00708482050.013
regulation of interferon gamma productionGO:0032649360.013
cellular response to nitrogen compoundGO:19016991440.013
regulation of protein kinase activityGO:00458592890.013
protein maturationGO:00516042330.013
type i interferon signaling pathwayGO:0060337110.013
positive regulation of peptidase activityGO:0010952880.013
muscle structure developmentGO:0061061980.013
negative regulation of defense response to virusGO:0050687100.013
intracellular transport of viral protein in host cellGO:001906040.013
cellular component morphogenesisGO:00329893140.013
negative regulation of phosphorus metabolic processGO:00105632670.012
atp catabolic processGO:00062001570.012
growthGO:00400072020.012
cell growthGO:00160491600.012
chromatin modificationGO:00165682980.012
regulation of protein localization to nucleusGO:1900180850.012
regulation of stress activated mapk cascadeGO:0032872840.012
cellular response to hormone stimulusGO:00328701250.012
regulation of synaptic plasticityGO:004816730.012
negative regulation of proteolysisGO:00458611320.012
isg15 protein conjugationGO:003202050.012
regulation of mapk cascadeGO:00434082620.012
ncrna processingGO:0034470830.012
positive regulation of cytokine productionGO:00018191670.012
mapk cascadeGO:00001652880.012
response to oxygen containing compoundGO:19017003690.012
adult locomotory behaviorGO:000834410.012
activation of cysteine type endopeptidase activityGO:0097202570.012
organic acid biosynthetic processGO:0016053970.012
epithelial cell proliferationGO:00506731280.012
negative regulation of protein maturationGO:19033181420.012
wnt signaling pathwayGO:00160551560.012
negative regulation of growthGO:0045926970.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
negative regulation of phosphorylationGO:00423261740.011
memoryGO:000761330.011
actin mediated cell contractionGO:0070252120.011
mrna metabolic processGO:00160711750.011
positive regulation of phosphorylationGO:00423273940.011
nuclear exportGO:0051168690.011
positive regulation of cellular component organizationGO:00511303760.011
regulation of cell migrationGO:00303342890.011
ncrna metabolic processGO:00346601080.011
transforming growth factor beta receptor signaling pathwayGO:0007179760.011
regulation of membrane depolarizationGO:0003254190.011
defense response to bacteriumGO:0042742630.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.011
circulatory system developmentGO:00723592620.011
monosaccharide metabolic processGO:0005996740.011
covalent chromatin modificationGO:00165692540.011
hindbrain developmentGO:003090230.011
cellular homeostasisGO:00197251960.011
neuromuscular junction developmentGO:000752830.011
regenerationGO:003109940.011
regulation of protein localizationGO:00328802960.011
regulation of cellular amine metabolic processGO:0033238110.011
regulation of mda 5 signaling pathwayGO:003953340.011
nervous system developmentGO:00073992930.011
protein sumoylationGO:0016925250.011
regulation of ribonuclease activityGO:006070030.011
intracellular protein transportGO:00068862700.011
inner ear morphogenesisGO:004247240.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of cell motilityGO:20001461040.010
vesicle mediated transportGO:00161923710.010
negative regulation of transferase activityGO:00513481240.010
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
negative regulation of transportGO:00510511760.010
regulation of proteolysisGO:00301622930.010
nucleoside monophosphate catabolic processGO:00091251590.010
regulation of growthGO:00400081650.010
negative regulation of signal transduction in absence of ligandGO:1901099160.010
ribonucleoprotein complex assemblyGO:0022618780.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
regulation of nucleotide metabolic processGO:00061402690.010
transcription factor import into nucleusGO:0042991400.010
nucleoside monophosphate metabolic processGO:00091231910.010
cellular lipid metabolic processGO:00442553030.010
regulation of neural precursor cell proliferationGO:200017740.010
regulation of ras protein signal transductionGO:00465781550.010
purine ribonucleoside metabolic processGO:00461284370.010
response to dsrnaGO:0043331250.010
protein homooligomerizationGO:00512601000.010
positive regulation of wnt signaling pathwayGO:0030177540.010
intracellular receptor signaling pathwayGO:00305221040.010

USP18 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
carbohydrate metabolism diseaseDOID:0050013320.027
disease of metabolismDOID:00146672950.027
glucose metabolism diseaseDOID:4194320.027
acquired metabolic diseaseDOID:0060158580.027
diabetes mellitusDOID:9351310.027
connective tissue diseaseDOID:651090.024
musculoskeletal system diseaseDOID:172230.024
bone diseaseDOID:0080001880.019
bone development diseaseDOID:0080006550.019
nervous system diseaseDOID:8634310.017
sensory system diseaseDOID:00501552030.017
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
central nervous system diseaseDOID:3311860.011